Last updated: 2022-08-20

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Cancer type RAS Non-RAS RAS(n) non-RAS(n) Group Mean 2.5% 97.5% n_eff Rhat 00 10 01 11 Driver -log10(p)
colorectal cancer KRAS_G12A SPEN 6 23 <40yrs -0.53 -2.46 1.20 1483.67 1.00 199 4 21 2 FALSE 0.25
colorectal cancer KRAS_G12A SPEN 14 25 40-50yrs -0.99 -3.15 0.65 1167.66 1.00 416 14 25 0 FALSE 0.51
colorectal cancer KRAS_G12A SPEN 16 45 50-65yrs -1.00 -3.14 0.52 1348.72 1.00 916 16 45 0 FALSE 0.55
colorectal cancer KRAS_G12A SPEN 16 62 >65yrs -1.07 -3.06 0.45 1324.58 1.00 589 16 62 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A SPEN 25 67 50-65yrs -0.01 -1.74 1.23 1351.08 1.00 1248 24 66 1 FALSE 0.00
non-small cell lung cancer KRAS_G12A SPEN 63 49 >65yrs 0.44 -0.88 1.53 1416.62 1.00 2027 60 46 3 FALSE 0.32
colorectal cancer KRAS_G12A SPEN 52 155 Age:overall -0.89 -2.77 0.61 1348.13 1.00 2120 50 153 2 FALSE 0.52
non-small cell lung cancer KRAS_G12A SPEN 88 116 Age:overall 0.22 -1.62 1.94 1594.23 1.00 3275 84 112 4 FALSE 0.09
non-small cell lung cancer KRAS_G12A KMT2C 25 90 50-65yrs -1.24 -4.23 0.26 1038.13 1.00 1205 25 90 0 FALSE 0.55
non-small cell lung cancer KRAS_G12A KMT2C 63 122 >65yrs -0.68 -2.07 0.46 1391.34 1.00 1945 60 119 3 FALSE 0.54
non-small cell lung cancer KRAS_G12A KMT2C 88 212 Age:overall -0.91 -2.89 0.56 1265.94 1.00 3150 85 209 3 FALSE 0.50
colorectal cancer KRAS_G12A TP53 15 350 40-50yrs -0.49 -1.05 0.14 1381.89 1.00 147 5 340 10 TRUE 0.96
colorectal cancer KRAS_G12A TP53 18 724 50-65yrs -0.66 -1.28 -0.08 1322.64 1.00 386 11 717 7 TRUE 1.49
colorectal cancer KRAS_G12A TP53 18 480 >65yrs -0.55 -1.15 0.05 1397.64 1.00 280 9 471 9 TRUE 1.20
non-small cell lung cancer KRAS_G12A TP53 27 814 50-65yrs -0.69 -1.34 -0.04 1425.50 1.00 604 15 802 12 TRUE 1.42
non-small cell lung cancer KRAS_G12A TP53 66 1113 >65yrs -0.90 -1.44 -0.40 1473.37 1.00 1103 48 1095 18 TRUE 3.18
colorectal cancer KRAS_G12A TP53 56 1719 Age:overall -0.57 -1.13 0.01 1355.33 1.00 893 27 1690 29 TRUE 1.29
non-small cell lung cancer KRAS_G12A TP53 93 2056 Age:overall -0.89 -1.87 -0.02 1460.53 1.00 1848 63 2026 30 TRUE 1.24
colorectal cancer KRAS_G12A ATRX 14 31 40-50yrs -0.36 -2.33 1.09 1202.87 1.00 413 14 31 0 TRUE 0.16
colorectal cancer KRAS_G12A ATRX 16 31 50-65yrs 0.33 -1.38 1.84 1519.12 1.00 924 14 29 2 TRUE 0.17
colorectal cancer KRAS_G12A ATRX 16 48 >65yrs -0.09 -1.75 1.23 1456.68 1.00 595 15 47 1 TRUE 0.04
non-small cell lung cancer KRAS_G12A ATRX 25 74 50-65yrs -0.73 -3.69 0.71 1156.63 1.00 1226 25 74 0 TRUE 0.26
non-small cell lung cancer KRAS_G12A ATRX 64 123 >65yrs 0.01 -1.06 0.95 1464.19 1.00 1964 59 118 5 TRUE 0.01
colorectal cancer KRAS_G12A ATRX 46 110 Age:overall -0.04 -1.68 1.23 1419.99 1.00 1932 43 107 3 TRUE 0.02
non-small cell lung cancer KRAS_G12A ATRX 89 197 Age:overall -0.34 -2.39 0.99 1270.17 1.00 3190 84 192 5 TRUE 0.16
colorectal cancer KRAS_G12A ATR 14 22 40-50yrs -4.55 -11.71 -0.65 132.81 1.05 424 14 22 0 FALSE 0.97
colorectal cancer KRAS_G12A ATR 16 48 50-65yrs -4.54 -11.63 -0.70 135.80 1.05 916 16 48 0 FALSE 0.98
colorectal cancer KRAS_G12A ATR 16 27 >65yrs -4.55 -11.54 -0.72 132.49 1.05 609 16 27 0 FALSE 0.98
non-small cell lung cancer KRAS_G12A ATR 26 50 50-65yrs 1.51 0.15 2.62 1324.28 1.00 1247 21 45 5 FALSE 1.75
non-small cell lung cancer KRAS_G12A ATR 63 73 >65yrs -1.85 -6.89 0.62 1380.98 1.00 1993 63 73 0 FALSE 0.43
colorectal cancer KRAS_G12A ATR 51 114 Age:overall -4.54 -11.63 -0.72 136.47 1.05 2149 51 114 0 FALSE 0.98
non-small cell lung cancer KRAS_G12A ATR 89 123 Age:overall -0.10 -3.95 2.52 1468.80 1.00 3240 84 118 5 FALSE 0.02
colorectal cancer KRAS_G12A PDGFRA 15 14 40-50yrs -4.47 -11.65 -0.02 925.01 1.00 455 15 14 0 TRUE 0.85
colorectal cancer KRAS_G12A PDGFRA 18 22 50-65yrs -4.49 -11.76 -0.10 842.25 1.00 1036 18 22 0 TRUE 0.86
colorectal cancer KRAS_G12A PDGFRA 18 12 >65yrs -4.46 -11.68 -0.08 878.04 1.00 691 18 12 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A PDGFRA 26 57 50-65yrs -0.16 -1.74 1.26 1252.87 1.00 1296 24 55 2 TRUE 0.08
non-small cell lung cancer KRAS_G12A PDGFRA 65 86 >65yrs -0.56 -2.33 0.60 1336.39 1.00 2038 64 85 1 TRUE 0.34
colorectal cancer KRAS_G12A PDGFRA 56 60 Age:overall -4.46 -11.73 -0.08 859.17 1.00 2404 56 60 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A PDGFRA 91 143 Age:overall -0.35 -2.16 1.24 1473.73 1.00 3334 88 140 3 TRUE 0.17
colorectal cancer KRAS_G12A FBXW7 15 60 40-50yrs 0.66 0.01 1.32 867.15 1.00 421 11 56 4 TRUE 1.31
colorectal cancer KRAS_G12A FBXW7 18 144 50-65yrs 0.64 0.00 1.27 955.22 1.00 936 12 138 6 TRUE 1.31
colorectal cancer KRAS_G12A FBXW7 19 107 >65yrs 0.59 -0.12 1.21 695.11 1.00 614 16 104 3 TRUE 1.11
non-small cell lung cancer KRAS_G12A FBXW7 26 32 50-65yrs -1.39 -4.87 0.65 586.93 1.01 1317 26 32 0 TRUE 0.48
non-small cell lung cancer KRAS_G12A FBXW7 65 51 >65yrs -1.17 -4.15 0.69 399.94 1.01 2073 64 50 1 TRUE 0.48
colorectal cancer KRAS_G12A FBXW7 57 339 Age:overall 0.63 0.01 1.23 804.82 1.00 2176 44 326 13 TRUE 1.31
non-small cell lung cancer KRAS_G12A FBXW7 91 83 Age:overall -1.25 -4.35 0.75 445.28 1.01 3390 90 82 1 TRUE 0.48
colorectal cancer KRAS_G12A MAP3K1 14 24 40-50yrs -1.11 -4.11 0.80 1205.72 1.00 418 13 23 1 FALSE 0.42
colorectal cancer KRAS_G12A MAP3K1 16 34 50-65yrs -1.27 -4.22 0.65 1086.44 1.00 919 16 34 0 FALSE 0.49
colorectal cancer KRAS_G12A MAP3K1 16 25 >65yrs -1.26 -4.31 0.66 1095.37 1.00 612 16 25 0 FALSE 0.48
non-small cell lung cancer KRAS_G12A MAP3K1 25 28 50-65yrs 0.07 -2.06 1.60 1279.17 1.00 1264 24 27 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A MAP3K1 63 33 >65yrs -0.05 -1.82 1.39 1259.06 1.00 2034 62 32 1 FALSE 0.02
colorectal cancer KRAS_G12A MAP3K1 46 83 Age:overall -1.21 -4.18 0.67 1065.12 1.00 1949 45 82 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A MAP3K1 88 61 Age:overall 0.03 -1.91 1.66 1240.70 1.00 3298 86 59 2 FALSE 0.01
colorectal cancer KRAS_G12A NSD1 14 16 40-50yrs -4.79 -12.24 -0.40 719.87 1.00 424 14 16 0 FALSE 0.93
colorectal cancer KRAS_G12A NSD1 16 22 50-65yrs -4.78 -12.19 -0.39 804.68 1.00 930 16 22 0 FALSE 0.92
colorectal cancer KRAS_G12A NSD1 16 33 >65yrs -4.81 -12.43 -0.45 748.91 1.00 607 16 33 0 FALSE 0.94
non-small cell lung cancer KRAS_G12A NSD1 25 31 50-65yrs 0.57 -1.00 1.82 444.51 1.01 1261 23 29 2 FALSE 0.40
non-small cell lung cancer KRAS_G12A NSD1 63 55 >65yrs 0.38 -1.01 1.46 394.09 1.00 2013 61 53 2 FALSE 0.26
colorectal cancer KRAS_G12A NSD1 51 86 Age:overall -4.78 -12.28 -0.45 742.81 1.00 2160 51 86 0 FALSE 0.93
non-small cell lung cancer KRAS_G12A NSD1 88 86 Age:overall 0.45 -1.03 1.76 458.28 1.00 3274 84 82 4 FALSE 0.28
colorectal cancer KRAS_G12A FLT4 14 24 40-50yrs -0.83 -3.08 0.73 1526.76 1.00 416 14 24 0 TRUE 0.41
colorectal cancer KRAS_G12A FLT4 16 42 50-65yrs -0.58 -2.50 0.95 1632.08 1.00 912 15 41 1 TRUE 0.29
colorectal cancer KRAS_G12A FLT4 16 63 >65yrs -0.72 -2.69 0.76 1377.14 1.00 582 15 62 1 TRUE 0.39
non-small cell lung cancer KRAS_G12A FLT4 25 43 50-65yrs 0.35 -1.26 1.48 783.30 1.01 1249 24 42 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A FLT4 64 54 >65yrs 0.46 -0.83 1.45 698.86 1.00 2016 61 51 3 TRUE 0.37
colorectal cancer KRAS_G12A FLT4 46 129 Age:overall -0.70 -2.52 0.81 1410.01 1.00 1910 44 127 2 TRUE 0.38
non-small cell lung cancer KRAS_G12A FLT4 89 97 Age:overall 0.42 -1.09 1.64 914.61 1.00 3265 85 93 4 TRUE 0.26
colorectal cancer KRAS_G12A PTPRD 14 18 40-50yrs 0.25 -1.43 1.31 76.26 1.05 424 14 18 0 FALSE 0.14
colorectal cancer KRAS_G12A PTPRD 16 43 50-65yrs 0.36 -1.06 1.45 93.82 1.04 917 14 41 2 FALSE 0.23
colorectal cancer KRAS_G12A PTPRD 16 32 >65yrs 0.31 -1.20 1.35 77.61 1.05 607 15 31 1 FALSE 0.19
non-small cell lung cancer KRAS_G12A PTPRD 26 163 50-65yrs 0.32 -0.52 1.22 86.87 1.05 1158 21 158 5 FALSE 0.30
non-small cell lung cancer KRAS_G12A PTPRD 63 214 >65yrs 0.13 -0.66 0.88 186.86 1.02 1888 56 207 7 FALSE 0.13
colorectal cancer KRAS_G12A PTPRD 46 93 Age:overall 0.31 -1.20 1.32 70.67 1.05 1948 43 90 3 FALSE 0.19
non-small cell lung cancer KRAS_G12A PTPRD 89 390 Age:overall 0.19 -0.98 1.42 1043.98 1.02 3227 77 378 12 FALSE 0.12
colorectal cancer KRAS_G12A RET 18 30 50-65yrs -4.26 -10.81 0.45 1362.62 1.00 1026 18 30 0 TRUE 0.82
colorectal cancer KRAS_G12A RET 18 20 >65yrs -4.28 -10.85 0.21 1374.51 1.00 684 18 20 0 TRUE 0.80
non-small cell lung cancer KRAS_G12A RET 26 29 50-65yrs -0.79 -3.57 0.88 1401.16 1.00 1319 26 29 0 TRUE 0.25
non-small cell lung cancer KRAS_G12A RET 65 61 >65yrs -0.37 -2.19 1.01 1281.31 1.00 2061 63 59 2 TRUE 0.19
colorectal cancer KRAS_G12A RET 36 50 Age:overall -4.20 -10.58 0.35 1421.90 1.00 1710 36 50 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A RET 91 90 Age:overall -0.55 -2.90 1.05 1408.86 1.00 3380 89 88 2 TRUE 0.22
colorectal cancer KRAS_G12A KDM5A 14 21 40-50yrs -4.81 -12.23 -0.42 1175.51 1.00 423 14 21 0 FALSE 0.96
colorectal cancer KRAS_G12A KDM5A 16 35 50-65yrs -4.82 -12.41 -0.39 1159.02 1.00 924 16 35 0 FALSE 0.96
colorectal cancer KRAS_G12A KDM5A 16 30 >65yrs -4.81 -12.44 -0.50 1123.85 1.00 605 16 30 0 FALSE 0.96
non-small cell lung cancer KRAS_G12A KDM5A 25 25 50-65yrs 0.42 -1.21 1.62 1151.28 1.01 1267 24 24 1 FALSE 0.25
non-small cell lung cancer KRAS_G12A KDM5A 63 45 >65yrs 0.36 -1.07 1.44 1286.78 1.00 2025 61 43 2 FALSE 0.26
colorectal cancer KRAS_G12A KDM5A 46 86 Age:overall -4.80 -12.32 -0.54 1124.83 1.00 1952 46 86 0 FALSE 0.97
non-small cell lung cancer KRAS_G12A KDM5A 88 70 Age:overall 0.39 -1.15 1.68 1114.28 1.00 3292 85 67 3 FALSE 0.24
colorectal cancer KRAS_G12A PIK3C2G 13 21 40-50yrs 0.56 -0.88 1.68 967.22 1.00 405 13 21 0 FALSE 0.41
colorectal cancer KRAS_G12A PIK3C2G 16 32 50-65yrs 0.73 -0.52 1.78 950.88 1.00 900 14 30 2 FALSE 0.63
colorectal cancer KRAS_G12A PIK3C2G 17 28 >65yrs 0.70 -0.48 1.82 958.11 1.00 593 15 26 2 FALSE 0.61
non-small cell lung cancer KRAS_G12A PIK3C2G 25 51 50-65yrs -0.22 -3.98 1.23 380.24 1.01 1236 25 51 0 FALSE 0.06
non-small cell lung cancer KRAS_G12A PIK3C2G 63 73 >65yrs 0.83 -0.15 1.62 1067.53 1.00 1996 57 67 6 FALSE 1.15
colorectal cancer KRAS_G12A PIK3C2G 46 81 Age:overall 0.66 -0.62 1.69 861.92 1.00 1898 42 77 4 FALSE 0.57
non-small cell lung cancer KRAS_G12A PIK3C2G 88 124 Age:overall 0.32 -2.16 1.79 1197.15 1.00 3232 82 118 6 FALSE 0.13
non-small cell lung cancer KRAS_G12A TSHR 25 23 50-65yrs -0.39 -3.33 1.34 1017.62 1.00 1267 25 23 0 TRUE 0.12
non-small cell lung cancer KRAS_G12A TSHR 63 42 >65yrs 0.02 -1.89 1.45 1402.41 1.00 2028 61 40 2 TRUE 0.01
non-small cell lung cancer KRAS_G12A TSHR 88 65 Age:overall -0.18 -2.64 1.53 1256.72 1.00 3295 86 63 2 TRUE 0.06
colorectal cancer KRAS_G12A CREBBP 14 31 40-50yrs -1.14 -3.21 0.38 1347.92 1.00 414 14 31 0 TRUE 0.70
colorectal cancer KRAS_G12A CREBBP 16 58 50-65yrs -0.98 -2.93 0.52 1466.21 1.00 908 15 57 1 TRUE 0.59
colorectal cancer KRAS_G12A CREBBP 16 81 >65yrs -1.03 -2.99 0.40 1436.19 1.00 572 15 80 1 TRUE 0.66
non-small cell lung cancer KRAS_G12A CREBBP 25 48 50-65yrs -0.71 -3.48 0.86 637.71 1.00 1245 25 48 0 TRUE 0.26
non-small cell lung cancer KRAS_G12A CREBBP 63 83 >65yrs -0.26 -1.82 0.93 177.19 1.01 1990 60 80 3 TRUE 0.14
colorectal cancer KRAS_G12A CREBBP 51 188 Age:overall -1.05 -2.92 0.35 1463.77 1.00 2092 49 186 2 TRUE 0.71
non-small cell lung cancer KRAS_G12A CREBBP 88 131 Age:overall -0.48 -3.11 0.95 346.96 1.01 3235 85 128 3 TRUE 0.21
non-small cell lung cancer KRAS_G12A BRIP1 25 30 50-65yrs 0.38 -1.32 1.63 1092.87 1.00 1262 24 29 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A BRIP1 63 40 >65yrs 0.40 -1.18 1.54 1243.30 1.00 2027 61 38 2 TRUE 0.25
non-small cell lung cancer KRAS_G12A BRIP1 88 70 Age:overall 0.40 -1.26 1.75 1296.12 1.00 3289 85 67 3 TRUE 0.22
colorectal cancer KRAS_G12A AXIN2 14 25 40-50yrs 0.76 -0.42 1.71 1034.86 1.00 419 12 23 2 TRUE 0.81
colorectal cancer KRAS_G12A AXIN2 16 45 50-65yrs 0.58 -0.70 1.56 847.82 1.01 913 16 45 0 TRUE 0.48
colorectal cancer KRAS_G12A AXIN2 16 39 >65yrs 0.80 -0.34 1.74 1187.38 1.00 602 13 36 3 TRUE 0.91
non-small cell lung cancer KRAS_G12A AXIN2 25 28 50-65yrs -1.02 -4.42 0.86 34.63 1.12 1262 25 28 0 TRUE 0.30
non-small cell lung cancer KRAS_G12A AXIN2 63 30 >65yrs -0.71 -3.52 1.01 42.48 1.12 2036 62 29 1 TRUE 0.24
colorectal cancer KRAS_G12A AXIN2 46 109 Age:overall 0.71 -0.49 1.65 924.69 1.00 1934 41 104 5 TRUE 0.74
non-small cell lung cancer KRAS_G12A AXIN2 88 58 Age:overall -0.84 -3.90 1.16 39.65 1.12 3298 87 57 1 TRUE 0.26
colorectal cancer KRAS_G12A DOT1L 14 12 40-50yrs -0.51 -2.87 1.23 1462.14 1.00 425 14 12 0 FALSE 0.20
colorectal cancer KRAS_G12A DOT1L 17 21 50-65yrs 0.20 -2.00 1.99 1430.11 1.00 935 15 19 2 FALSE 0.08
colorectal cancer KRAS_G12A DOT1L 16 32 >65yrs -0.62 -2.93 1.08 1500.19 1.00 605 16 32 0 FALSE 0.26
non-small cell lung cancer KRAS_G12A DOT1L 25 35 50-65yrs -0.45 -2.34 1.18 1105.29 1.00 1257 24 34 1 FALSE 0.21
non-small cell lung cancer KRAS_G12A DOT1L 63 66 >65yrs -0.64 -2.53 0.82 1166.14 1.00 2002 62 65 1 FALSE 0.34
colorectal cancer KRAS_G12A DOT1L 52 84 Age:overall -0.37 -2.42 1.25 1487.32 1.00 2162 50 82 2 FALSE 0.16
non-small cell lung cancer KRAS_G12A DOT1L 88 101 Age:overall -0.53 -2.50 1.04 1263.24 1.00 3259 86 99 2 FALSE 0.25
non-small cell lung cancer KRAS_G12A PTPRS 25 31 50-65yrs -1.35 -4.47 0.67 1110.29 1.00 1253 25 31 0 FALSE 0.50
non-small cell lung cancer KRAS_G12A PTPRS 63 46 >65yrs -1.14 -3.78 0.73 1005.68 1.00 2019 62 45 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A PTPRS 88 77 Age:overall -1.23 -4.09 0.74 896.60 1.00 3272 87 76 1 FALSE 0.49
colorectal cancer KRAS_G12A SMARCA4 6 19 <40yrs 0.86 -0.17 2.02 1294.43 1.00 200 3 16 3 FALSE 0.92
colorectal cancer KRAS_G12A SMARCA4 14 24 40-50yrs 0.70 -0.31 1.60 1362.74 1.00 418 12 22 2 FALSE 0.82
colorectal cancer KRAS_G12A SMARCA4 17 65 50-65yrs 0.64 -0.38 1.53 1263.85 1.00 903 15 63 2 FALSE 0.74
colorectal cancer KRAS_G12A SMARCA4 16 61 >65yrs 0.43 -0.82 1.32 1295.34 1.00 585 16 61 0 FALSE 0.36
non-small cell lung cancer KRAS_G12A SMARCA4 25 119 50-65yrs -1.32 -4.78 0.30 790.60 1.00 1174 25 119 0 FALSE 0.47
non-small cell lung cancer KRAS_G12A SMARCA4 63 174 >65yrs -0.13 -1.20 0.71 1001.94 1.00 1915 57 168 6 FALSE 0.10
colorectal cancer KRAS_G12A SMARCA4 53 169 Age:overall 0.66 -0.30 1.53 1263.15 1.00 2106 46 162 7 FALSE 0.80
non-small cell lung cancer KRAS_G12A SMARCA4 88 312 Age:overall -0.72 -3.06 0.85 1091.33 1.00 3262 82 306 6 FALSE 0.31
colorectal cancer KRAS_G12A PTPRT 14 39 40-50yrs -1.03 -2.90 0.38 855.56 1.00 405 14 39 0 FALSE 0.67
colorectal cancer KRAS_G12A PTPRT 16 80 50-65yrs -1.04 -2.90 0.34 836.49 1.00 876 16 80 0 FALSE 0.69
colorectal cancer KRAS_G12A PTPRT 16 48 >65yrs -0.98 -2.90 0.39 786.18 1.00 590 15 47 1 FALSE 0.64
non-small cell lung cancer KRAS_G12A PTPRT 25 152 50-65yrs -0.31 -1.58 0.72 1545.07 1.00 1178 23 150 2 FALSE 0.22
non-small cell lung cancer KRAS_G12A PTPRT 65 175 >65yrs -0.02 -0.84 0.73 1592.58 1.00 1916 59 169 6 FALSE 0.02
colorectal cancer KRAS_G12A PTPRT 51 185 Age:overall -1.01 -2.84 0.36 809.29 1.00 2070 49 183 2 FALSE 0.67
non-small cell lung cancer KRAS_G12A PTPRT 90 349 Age:overall -0.20 -1.54 1.02 1570.36 1.00 3265 82 341 8 FALSE 0.12
colorectal cancer KRAS_G12A HGF 16 24 50-65yrs -3.15 -11.32 0.26 8.44 1.13 929 16 24 0 FALSE 0.51
colorectal cancer KRAS_G12A HGF 16 15 >65yrs -3.12 -10.92 0.37 9.02 1.13 619 16 15 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A HGF 25 78 50-65yrs 0.03 -1.24 1.07 1443.41 1.00 1219 23 76 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A HGF 63 105 >65yrs -0.03 -1.17 0.92 1569.37 1.00 1971 60 102 3 FALSE 0.02
colorectal cancer KRAS_G12A HGF 32 39 Age:overall -3.09 -10.99 0.25 8.61 1.13 1548 32 39 0 FALSE 0.52
non-small cell lung cancer KRAS_G12A HGF 88 183 Age:overall 0.00 -1.41 1.16 1442.72 1.00 3190 83 178 5 FALSE 0.00
colorectal cancer KRAS_G12A BLM 14 14 40-50yrs -4.66 -11.89 0.00 507.31 1.01 426 14 14 0 TRUE 0.86
colorectal cancer KRAS_G12A BLM 16 21 50-65yrs -4.65 -11.88 0.09 508.48 1.01 931 16 21 0 TRUE 0.87
colorectal cancer KRAS_G12A BLM 16 26 >65yrs -4.65 -11.71 0.09 507.27 1.01 610 16 26 0 TRUE 0.86
colorectal cancer KRAS_G12A BLM 46 61 Age:overall -4.64 -11.75 -0.04 500.06 1.01 1967 46 61 0 TRUE 0.87
colorectal cancer KRAS_G12A PIK3CA 15 90 40-50yrs -0.01 -0.82 0.65 657.18 1.00 390 14 89 1 TRUE 0.01
colorectal cancer KRAS_G12A PIK3CA 18 213 50-65yrs 0.05 -0.66 0.71 675.25 1.00 870 13 208 5 TRUE 0.05
colorectal cancer KRAS_G12A PIK3CA 19 166 >65yrs 0.06 -0.67 0.72 665.99 1.00 563 14 161 5 TRUE 0.06
non-small cell lung cancer KRAS_G12A PIK3CA 26 90 50-65yrs -0.02 -1.20 0.96 1042.89 1.00 1262 24 88 2 TRUE 0.02
non-small cell lung cancer KRAS_G12A PIK3CA 66 140 >65yrs -0.06 -1.03 0.73 459.60 1.01 1988 62 136 4 TRUE 0.04
colorectal cancer KRAS_G12A PIK3CA 57 511 Age:overall 0.03 -0.69 0.66 578.84 1.00 2016 45 499 12 TRUE 0.03
non-small cell lung cancer KRAS_G12A PIK3CA 92 230 Age:overall -0.04 -1.19 0.94 935.56 1.00 3250 86 224 6 TRUE 0.03
non-small cell lung cancer KRAS_G12A GATA3 25 27 50-65yrs -0.68 -3.60 1.26 444.22 1.01 1266 24 26 1 FALSE 0.25
non-small cell lung cancer KRAS_G12A GATA3 63 36 >65yrs -1.14 -4.66 0.70 270.96 1.01 2031 63 36 0 FALSE 0.34
non-small cell lung cancer KRAS_G12A GATA3 88 63 Age:overall -0.88 -3.90 1.13 424.85 1.02 3297 87 62 1 FALSE 0.32
colorectal cancer KRAS_G12A ESR1 16 24 50-65yrs -0.88 -3.90 1.16 759.47 1.00 927 16 24 0 TRUE 0.30
colorectal cancer KRAS_G12A ESR1 16 28 >65yrs -0.92 -3.97 1.05 642.42 1.00 608 16 28 0 TRUE 0.33
non-small cell lung cancer KRAS_G12A ESR1 25 18 50-65yrs -4.98 -12.00 -0.08 137.56 1.02 1273 25 18 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A ESR1 63 34 >65yrs -4.99 -12.08 -0.24 143.53 1.02 2033 63 34 0 TRUE 0.90
colorectal cancer KRAS_G12A ESR1 37 64 Age:overall -0.80 -3.49 1.14 598.39 1.01 1737 36 63 1 TRUE 0.30
non-small cell lung cancer KRAS_G12A ESR1 88 52 Age:overall -4.95 -12.02 -0.15 135.39 1.02 3306 88 52 0 TRUE 0.89
colorectal cancer KRAS_G12A ALK 15 25 40-50yrs -1.38 -4.08 0.47 176.13 1.02 450 15 25 0 TRUE 0.60
colorectal cancer KRAS_G12A ALK 18 44 50-65yrs -1.34 -4.07 0.48 191.28 1.02 1014 17 43 1 TRUE 0.58
colorectal cancer KRAS_G12A ALK 18 32 >65yrs -1.38 -4.07 0.44 171.01 1.02 673 18 32 0 TRUE 0.60
non-small cell lung cancer KRAS_G12A ALK 26 76 50-65yrs -2.10 -5.42 0.02 1357.22 1.00 1278 26 76 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A ALK 65 81 >65yrs -1.75 -4.51 0.16 1490.59 1.00 2041 64 80 1 TRUE 0.85
colorectal cancer KRAS_G12A ALK 56 115 Age:overall -1.37 -4.00 0.42 175.26 1.02 2361 55 114 1 TRUE 0.60
non-small cell lung cancer KRAS_G12A ALK 91 157 Age:overall -1.85 -4.94 0.29 1398.24 1.00 3319 90 156 1 TRUE 0.82
colorectal cancer KRAS_G12A RNF43 14 26 40-50yrs -2.47 -5.41 -0.26 1315.28 1.00 413 14 26 0 TRUE 1.21
colorectal cancer KRAS_G12A RNF43 16 87 50-65yrs -2.16 -5.11 -0.10 1554.36 1.00 883 15 86 1 TRUE 1.05
colorectal cancer KRAS_G12A RNF43 16 123 >65yrs -2.55 -5.65 -0.57 1355.66 1.00 551 16 123 0 TRUE 1.34
colorectal cancer KRAS_G12A RNF43 51 267 Age:overall -2.40 -5.43 -0.49 1398.05 1.00 2035 50 266 1 TRUE 1.27
non-small cell lung cancer KRAS_G12A U2AF1 25 24 50-65yrs 0.98 -0.44 2.07 1285.91 1.00 1267 24 23 1 FALSE 0.92
non-small cell lung cancer KRAS_G12A U2AF1 64 51 >65yrs 1.16 0.19 2.01 1342.47 1.00 2020 59 46 5 FALSE 1.92
non-small cell lung cancer KRAS_G12A U2AF1 89 75 Age:overall 1.06 -0.36 2.25 1423.69 1.00 3287 83 69 6 FALSE 0.96
non-small cell lung cancer KRAS_G12A LATS1 25 27 50-65yrs -1.36 -4.34 0.87 295.97 1.01 1258 25 27 0 FALSE 0.45
non-small cell lung cancer KRAS_G12A LATS1 63 37 >65yrs -1.10 -3.79 0.94 146.78 1.02 2022 62 36 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A LATS1 88 64 Age:overall -1.21 -4.01 1.03 232.64 1.01 3280 87 63 1 FALSE 0.43
non-small cell lung cancer KRAS_G12A LATS2 25 24 50-65yrs -4.25 -11.22 0.03 609.65 1.00 1263 25 24 0 FALSE 0.79
non-small cell lung cancer KRAS_G12A LATS2 63 36 >65yrs -4.26 -11.16 -0.04 598.12 1.00 2022 63 36 0 FALSE 0.80
non-small cell lung cancer KRAS_G12A LATS2 88 60 Age:overall -4.18 -11.03 0.09 575.95 1.00 3285 88 60 0 FALSE 0.79
colorectal cancer KRAS_G12A PTEN 15 45 40-50yrs -1.00 -3.00 0.34 39.32 1.07 437 14 44 1 TRUE 0.57
colorectal cancer KRAS_G12A PTEN 18 65 50-65yrs -0.99 -3.00 0.41 40.80 1.07 1005 17 64 1 TRUE 0.56
colorectal cancer KRAS_G12A PTEN 18 59 >65yrs -1.06 -3.02 0.30 39.14 1.07 661 18 59 0 TRUE 0.61
non-small cell lung cancer KRAS_G12A PTEN 26 40 50-65yrs -1.11 -4.15 0.66 1420.65 1.00 1309 26 40 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A PTEN 65 87 >65yrs -0.72 -2.52 0.60 1101.20 1.00 2038 63 85 2 TRUE 0.44
colorectal cancer KRAS_G12A PTEN 56 185 Age:overall -1.02 -3.01 0.31 38.72 1.07 2322 54 183 2 TRUE 0.59
non-small cell lung cancer KRAS_G12A PTEN 91 127 Age:overall -0.91 -3.16 0.78 1302.36 1.00 3347 89 125 2 TRUE 0.40
colorectal cancer KRAS_G12A BCOR 14 14 40-50yrs -1.42 -4.42 0.58 1308.22 1.00 423 14 14 0 FALSE 0.61
colorectal cancer KRAS_G12A BCOR 16 40 50-65yrs -1.43 -4.38 0.50 1326.85 1.00 917 16 40 0 FALSE 0.61
colorectal cancer KRAS_G12A BCOR 16 47 >65yrs -1.45 -4.17 0.42 1320.56 1.00 595 16 47 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A BCOR 25 46 50-65yrs -0.67 -2.53 0.92 1155.53 1.00 1249 24 45 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A BCOR 63 84 >65yrs -0.85 -2.70 0.50 1066.47 1.00 1989 62 83 1 FALSE 0.53
colorectal cancer KRAS_G12A BCOR 51 112 Age:overall -1.37 -4.20 0.53 1301.45 1.00 2139 50 111 1 FALSE 0.61
non-small cell lung cancer KRAS_G12A BCOR 88 130 Age:overall -0.76 -2.63 0.84 1017.37 1.00 3238 86 128 2 FALSE 0.40
colorectal cancer KRAS_G12A CTNNB1 15 27 40-50yrs -0.42 -2.00 0.72 578.05 1.00 444 15 27 0 TRUE 0.26
colorectal cancer KRAS_G12A CTNNB1 18 76 50-65yrs -0.40 -1.95 0.76 554.43 1.00 985 17 75 1 TRUE 0.25
colorectal cancer KRAS_G12A CTNNB1 18 40 >65yrs -0.32 -1.67 0.80 497.12 1.00 666 16 38 2 TRUE 0.20
non-small cell lung cancer KRAS_G12A CTNNB1 26 43 50-65yrs -0.52 -2.98 0.94 737.63 1.01 1305 26 43 0 TRUE 0.20
non-small cell lung cancer KRAS_G12A CTNNB1 65 71 >65yrs -0.08 -1.57 1.00 445.25 1.01 2052 62 68 3 TRUE 0.04
colorectal cancer KRAS_G12A CTNNB1 56 163 Age:overall -0.38 -1.84 0.70 533.23 1.00 2307 53 160 3 TRUE 0.25
non-small cell lung cancer KRAS_G12A CTNNB1 91 114 Age:overall -0.29 -2.25 1.02 601.79 1.01 3357 88 111 3 TRUE 0.13
colorectal cancer KRAS_G12A ARID1A 14 51 40-50yrs -0.69 -2.08 0.44 1101.35 1.00 404 13 50 1 TRUE 0.56
colorectal cancer KRAS_G12A ARID1A 16 114 50-65yrs -0.81 -2.24 0.23 1256.00 1.00 865 16 114 0 TRUE 0.70
colorectal cancer KRAS_G12A ARID1A 16 110 >65yrs -0.75 -2.10 0.34 1099.87 1.00 559 15 109 1 TRUE 0.64
non-small cell lung cancer KRAS_G12A ARID1A 25 117 50-65yrs -0.80 -2.37 0.37 699.45 1.00 1185 24 116 1 TRUE 0.57
non-small cell lung cancer KRAS_G12A ARID1A 64 149 >65yrs -0.63 -1.97 0.36 975.67 1.00 1931 61 146 3 TRUE 0.54
colorectal cancer KRAS_G12A ARID1A 51 315 Age:overall -0.70 -2.00 0.33 940.02 1.00 2017 47 311 4 TRUE 0.62
non-small cell lung cancer KRAS_G12A ARID1A 89 282 Age:overall -0.75 -2.52 0.53 1336.75 1.00 3292 85 278 4 TRUE 0.45
colorectal cancer KRAS_G12A PIK3R1 14 21 40-50yrs -1.40 -3.90 0.44 817.99 1.00 419 13 20 1 TRUE 0.68
colorectal cancer KRAS_G12A PIK3R1 16 48 50-65yrs -1.46 -3.93 0.32 780.91 1.00 910 16 48 0 TRUE 0.73
colorectal cancer KRAS_G12A PIK3R1 16 36 >65yrs -1.45 -4.11 0.38 792.37 1.00 604 16 36 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A PIK3R1 25 18 50-65yrs -4.07 -11.22 0.21 240.66 1.02 1272 25 18 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A PIK3R1 63 35 >65yrs -4.10 -11.12 -0.07 228.75 1.02 2032 63 35 0 TRUE 0.86
colorectal cancer KRAS_G12A PIK3R1 51 116 Age:overall -1.44 -3.86 0.35 791.52 1.00 2136 50 115 1 TRUE 0.73
non-small cell lung cancer KRAS_G12A PIK3R1 88 53 Age:overall -4.01 -10.85 0.13 256.37 1.02 3304 88 53 0 TRUE 0.84
colorectal cancer KRAS_G12A IKZF1 14 13 40-50yrs -4.71 -11.86 -0.27 934.71 1.00 423 14 13 0 TRUE 0.90
colorectal cancer KRAS_G12A IKZF1 16 31 50-65yrs -4.71 -11.70 -0.22 930.56 1.00 923 16 31 0 TRUE 0.90
colorectal cancer KRAS_G12A IKZF1 16 33 >65yrs -4.74 -12.06 -0.38 881.41 1.00 603 16 33 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A IKZF1 25 44 50-65yrs 0.16 -1.58 1.50 1261.70 1.00 1248 24 43 1 TRUE 0.08
non-small cell lung cancer KRAS_G12A IKZF1 63 34 >65yrs 0.35 -1.19 1.61 1363.99 1.00 2034 61 32 2 TRUE 0.21
colorectal cancer KRAS_G12A IKZF1 46 77 Age:overall -4.70 -11.71 -0.34 914.22 1.00 1949 46 77 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A IKZF1 88 78 Age:overall 0.24 -1.58 1.90 1434.60 1.00 3282 85 75 3 TRUE 0.11
colorectal cancer KRAS_G12A TERT 14 23 40-50yrs -4.73 -11.55 -0.46 1162.10 1.00 421 14 23 0 TRUE 1.00
colorectal cancer KRAS_G12A TERT 16 39 50-65yrs -4.73 -11.45 -0.44 1162.70 1.00 913 16 39 0 TRUE 1.00
colorectal cancer KRAS_G12A TERT 16 27 >65yrs -4.74 -11.39 -0.52 1130.77 1.00 608 16 27 0 TRUE 1.01
non-small cell lung cancer KRAS_G12A TERT 25 59 50-65yrs 0.21 -0.94 1.30 1018.50 1.00 1235 23 57 2 TRUE 0.14
non-small cell lung cancer KRAS_G12A TERT 63 99 >65yrs 0.11 -1.07 0.98 664.92 1.00 1976 60 96 3 TRUE 0.08
colorectal cancer KRAS_G12A TERT 46 89 Age:overall -4.73 -11.32 -0.50 1150.41 1.00 1942 46 89 0 TRUE 1.01
non-small cell lung cancer KRAS_G12A TERT 88 158 Age:overall 0.15 -1.14 1.27 880.06 1.00 3211 83 153 5 TRUE 0.09
colorectal cancer KRAS_G12A FAT1 6 24 <40yrs 0.36 -0.79 1.57 1360.83 1.00 201 3 21 3 FALSE 0.28
colorectal cancer KRAS_G12A FAT1 14 39 40-50yrs 0.13 -0.97 1.11 1414.33 1.00 413 13 38 1 FALSE 0.09
colorectal cancer KRAS_G12A FAT1 16 81 50-65yrs 0.06 -1.00 0.97 1500.08 1.00 899 15 80 1 FALSE 0.05
colorectal cancer KRAS_G12A FAT1 16 83 >65yrs 0.05 -1.10 0.93 1335.13 1.00 574 15 82 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A FAT1 25 103 50-65yrs -0.65 -1.96 0.40 891.52 1.01 1196 24 102 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A FAT1 63 194 >65yrs -0.54 -1.55 0.42 597.05 1.01 1898 59 190 4 FALSE 0.55
colorectal cancer KRAS_G12A FAT1 52 227 Age:overall 0.15 -0.86 1.02 1428.53 1.00 2087 46 221 6 FALSE 0.13
non-small cell lung cancer KRAS_G12A FAT1 88 297 Age:overall -0.60 -1.98 0.50 715.29 1.01 3094 83 292 5 FALSE 0.44
colorectal cancer KRAS_G12A FGFR4 16 17 50-65yrs -4.28 -11.66 0.52 708.50 1.00 935 16 17 0 TRUE 0.71
colorectal cancer KRAS_G12A FGFR4 16 21 >65yrs -4.27 -11.47 0.55 685.74 1.00 616 16 21 0 TRUE 0.72
colorectal cancer KRAS_G12A FGFR4 32 38 Age:overall -4.19 -11.45 0.57 708.63 1.00 1551 32 38 0 TRUE 0.71
colorectal cancer KRAS_G12A CIC 14 25 40-50yrs -0.37 -2.07 0.91 1378.28 1.00 418 14 25 0 TRUE 0.21
colorectal cancer KRAS_G12A CIC 16 39 50-65yrs -0.25 -1.85 1.07 1400.56 1.00 919 15 38 1 TRUE 0.14
colorectal cancer KRAS_G12A CIC 17 58 >65yrs -0.19 -1.68 0.98 1495.62 1.00 590 15 56 2 TRUE 0.11
non-small cell lung cancer KRAS_G12A CIC 25 21 50-65yrs 0.23 -1.65 1.90 1446.81 1.00 1273 24 20 1 TRUE 0.10
non-small cell lung cancer KRAS_G12A CIC 63 66 >65yrs 0.01 -1.47 1.10 1483.85 1.00 2009 61 64 2 TRUE 0.01
colorectal cancer KRAS_G12A CIC 52 137 Age:overall -0.28 -1.77 0.94 1391.74 1.00 2127 49 134 3 TRUE 0.16
non-small cell lung cancer KRAS_G12A CIC 88 87 Age:overall 0.13 -1.58 1.67 1369.68 1.00 3282 85 84 3 TRUE 0.06
colorectal cancer KRAS_G12A KDM6A 14 11 40-50yrs -0.64 -3.48 1.15 545.60 1.00 426 14 11 0 FALSE 0.23
colorectal cancer KRAS_G12A KDM6A 16 26 50-65yrs -0.65 -3.46 1.12 630.17 1.00 926 16 26 0 FALSE 0.24
colorectal cancer KRAS_G12A KDM6A 16 20 >65yrs -0.55 -3.22 1.22 521.12 1.00 616 15 19 1 FALSE 0.20
non-small cell lung cancer KRAS_G12A KDM6A 25 27 50-65yrs -0.06 -3.47 1.53 1001.53 1.00 1265 25 27 0 FALSE 0.02
non-small cell lung cancer KRAS_G12A KDM6A 64 33 >65yrs 0.68 -0.87 1.86 1281.92 1.00 2036 61 30 3 FALSE 0.49
colorectal cancer KRAS_G12A KDM6A 46 57 Age:overall -0.62 -3.29 1.14 548.24 1.00 1968 45 56 1 FALSE 0.23
non-small cell lung cancer KRAS_G12A KDM6A 89 60 Age:overall 0.33 -2.17 1.95 1059.38 1.00 3301 86 57 3 FALSE 0.12
colorectal cancer KRAS_G12A NCOR1 14 22 40-50yrs -0.20 -1.58 1.01 1134.44 1.00 419 14 22 0 FALSE 0.12
colorectal cancer KRAS_G12A NCOR1 16 56 50-65yrs -0.15 -1.46 0.99 1151.43 1.00 906 15 55 1 FALSE 0.09
colorectal cancer KRAS_G12A NCOR1 16 45 >65yrs -0.11 -1.42 0.97 1167.79 1.00 598 14 43 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A NCOR1 25 41 50-65yrs 0.50 -0.94 1.63 1302.85 1.00 1255 24 40 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A NCOR1 63 56 >65yrs 0.72 -0.36 1.67 1445.93 1.00 2018 59 52 4 FALSE 0.78
colorectal cancer KRAS_G12A NCOR1 51 135 Age:overall -0.15 -1.47 0.96 1176.01 1.00 2127 48 132 3 FALSE 0.10
non-small cell lung cancer KRAS_G12A NCOR1 88 97 Age:overall 0.61 -0.72 1.77 1055.17 1.00 3273 83 92 5 FALSE 0.47
colorectal cancer KRAS_G12A POLE 14 23 40-50yrs -0.31 -1.93 0.96 1270.27 1.00 418 14 23 0 TRUE 0.18
colorectal cancer KRAS_G12A POLE 16 51 50-65yrs -0.13 -1.70 1.08 1280.94 1.00 912 14 49 2 TRUE 0.07
colorectal cancer KRAS_G12A POLE 16 45 >65yrs -0.24 -1.78 1.02 1249.32 1.00 596 15 44 1 TRUE 0.14
non-small cell lung cancer KRAS_G12A POLE 25 56 50-65yrs -0.27 -1.89 1.03 1464.93 1.00 1238 24 55 1 TRUE 0.15
non-small cell lung cancer KRAS_G12A POLE 63 75 >65yrs -0.27 -1.69 0.86 1355.13 1.00 1998 61 73 2 TRUE 0.17
colorectal cancer KRAS_G12A POLE 51 141 Age:overall -0.25 -1.71 0.94 1255.69 1.00 2123 48 138 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A POLE 88 131 Age:overall -0.26 -1.86 1.07 1384.34 1.00 3236 85 128 3 TRUE 0.14
non-small cell lung cancer KRAS_G12A CUL3 25 24 50-65yrs -1.33 -4.33 0.60 1043.43 1.01 1269 25 24 0 FALSE 0.56
non-small cell lung cancer KRAS_G12A CUL3 63 50 >65yrs -1.14 -3.66 0.60 988.58 1.00 2021 62 49 1 FALSE 0.60
non-small cell lung cancer KRAS_G12A CUL3 88 74 Age:overall -1.21 -3.92 0.59 1075.71 1.00 3290 87 73 1 FALSE 0.59
colorectal cancer KRAS_G12A ABL1 15 14 40-50yrs -4.89 -10.87 -0.15 32.74 1.09 459 15 14 0 TRUE 0.92
colorectal cancer KRAS_G12A ABL1 18 29 50-65yrs -4.89 -11.01 -0.15 32.46 1.09 1031 18 29 0 TRUE 0.92
colorectal cancer KRAS_G12A ABL1 18 24 >65yrs -4.92 -11.10 -0.17 32.63 1.08 679 18 24 0 TRUE 0.92
colorectal cancer KRAS_G12A ABL1 51 67 Age:overall -4.90 -11.00 -0.21 32.01 1.09 2169 51 67 0 TRUE 0.93
colorectal cancer KRAS_G12A FOXP1 14 17 40-50yrs -0.95 -3.83 1.06 325.39 1.01 421 14 17 0 FALSE 0.36
colorectal cancer KRAS_G12A FOXP1 16 27 50-65yrs -0.95 -3.64 0.89 365.77 1.01 926 16 27 0 FALSE 0.37
colorectal cancer KRAS_G12A FOXP1 16 14 >65yrs -0.96 -3.87 1.01 343.86 1.01 619 16 14 0 FALSE 0.36
colorectal cancer KRAS_G12A FOXP1 51 70 Age:overall -0.92 -3.64 1.00 342.75 1.01 2169 50 69 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A NOTCH2 25 43 50-65yrs -4.97 -11.76 -0.62 817.61 1.00 1250 25 43 0 TRUE 1.04
non-small cell lung cancer KRAS_G12A NOTCH2 63 67 >65yrs -4.99 -11.71 -0.87 787.14 1.00 1993 63 67 0 TRUE 1.10
non-small cell lung cancer KRAS_G12A NOTCH2 88 110 Age:overall -4.95 -11.68 -0.62 794.39 1.00 3243 88 110 0 TRUE 1.06
non-small cell lung cancer KRAS_G12A DDR2 25 39 50-65yrs -4.84 -11.74 -0.50 957.82 1.00 1251 25 39 0 TRUE 0.94
non-small cell lung cancer KRAS_G12A DDR2 63 56 >65yrs -4.93 -11.90 -0.60 1061.70 1.00 2009 63 56 0 TRUE 0.98
non-small cell lung cancer KRAS_G12A DDR2 88 95 Age:overall -4.82 -11.61 -0.53 1005.08 1.00 3260 88 95 0 TRUE 0.97
colorectal cancer KRAS_G12A TGFBR2 14 18 40-50yrs -1.25 -4.69 0.84 349.05 1.00 420 13 17 1 TRUE 0.47
colorectal cancer KRAS_G12A TGFBR2 16 42 50-65yrs -1.49 -4.84 0.44 367.43 1.00 912 16 42 0 TRUE 0.60
colorectal cancer KRAS_G12A TGFBR2 16 46 >65yrs -1.48 -4.78 0.52 377.29 1.00 589 16 46 0 TRUE 0.62
non-small cell lung cancer KRAS_G12A TGFBR2 25 28 50-65yrs -4.68 -12.16 -0.02 1321.90 1.00 1265 25 28 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A TGFBR2 63 26 >65yrs -4.68 -11.92 -0.05 1341.27 1.00 2040 63 26 0 TRUE 0.90
colorectal cancer KRAS_G12A TGFBR2 46 106 Age:overall -1.41 -4.73 0.55 347.37 1.00 1921 45 105 1 TRUE 0.58
non-small cell lung cancer KRAS_G12A TGFBR2 88 54 Age:overall -4.62 -11.99 0.05 1342.19 1.00 3305 88 54 0 TRUE 0.87
colorectal cancer KRAS_G12A SMO 15 14 40-50yrs -4.53 -11.06 -0.14 155.42 1.01 457 15 14 0 TRUE 0.88
colorectal cancer KRAS_G12A SMO 18 29 50-65yrs -4.52 -11.14 -0.33 152.91 1.01 1030 18 29 0 TRUE 0.88
colorectal cancer KRAS_G12A SMO 18 21 >65yrs -4.54 -11.24 -0.33 153.30 1.01 683 18 21 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A SMO 26 25 50-65yrs -0.07 -2.10 1.54 1276.80 1.00 1325 25 24 1 TRUE 0.03
non-small cell lung cancer KRAS_G12A SMO 65 45 >65yrs -0.25 -2.28 1.20 1213.56 1.00 2075 64 44 1 TRUE 0.11
colorectal cancer KRAS_G12A SMO 51 64 Age:overall -4.51 -10.98 -0.29 151.01 1.01 2170 51 64 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A SMO 91 70 Age:overall -0.13 -2.17 1.51 1292.60 1.00 3400 89 68 2 TRUE 0.05
colorectal cancer KRAS_G12A KMT2A 14 22 40-50yrs -4.98 -11.55 -0.97 1096.43 1.00 421 14 22 0 FALSE 1.11
colorectal cancer KRAS_G12A KMT2A 16 53 50-65yrs -4.99 -11.67 -1.03 1082.81 1.00 909 16 53 0 FALSE 1.12
colorectal cancer KRAS_G12A KMT2A 16 51 >65yrs -5.01 -11.44 -1.04 1062.58 1.00 593 16 51 0 FALSE 1.14
non-small cell lung cancer KRAS_G12A KMT2A 25 33 50-65yrs -1.77 -5.61 0.44 1122.55 1.00 1257 25 33 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A KMT2A 63 75 >65yrs -1.52 -4.54 0.33 1054.67 1.00 1997 62 74 1 FALSE 0.67
colorectal cancer KRAS_G12A KMT2A 51 148 Age:overall -4.99 -11.41 -1.00 1071.89 1.00 2119 51 148 0 FALSE 1.13
non-small cell lung cancer KRAS_G12A KMT2A 88 108 Age:overall -1.63 -4.92 0.54 1047.99 1.00 3254 87 107 1 FALSE 0.63
colorectal cancer KRAS_G12A JAK3 18 28 50-65yrs -4.16 -11.86 0.18 213.05 1.01 1029 18 28 0 TRUE 0.72
colorectal cancer KRAS_G12A JAK3 18 22 >65yrs -4.14 -11.51 0.25 208.33 1.01 684 18 22 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A JAK3 26 33 50-65yrs -0.24 -2.25 1.40 1312.79 1.00 1317 25 32 1 TRUE 0.10
non-small cell lung cancer KRAS_G12A JAK3 65 48 >65yrs -0.38 -2.25 1.04 1286.53 1.00 2072 64 47 1 TRUE 0.19
colorectal cancer KRAS_G12A JAK3 36 50 Age:overall -4.08 -11.44 0.25 244.15 1.01 1713 36 50 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A JAK3 91 81 Age:overall -0.31 -2.31 1.26 1293.17 1.00 3389 89 79 2 TRUE 0.13
non-small cell lung cancer KRAS_G12A PAK7 26 45 50-65yrs 0.51 -1.13 2.01 248.07 1.02 1244 23 42 3 FALSE 0.27
non-small cell lung cancer KRAS_G12A PAK7 63 81 >65yrs -1.46 -6.00 0.57 732.80 1.01 1983 63 81 0 FALSE 0.40
non-small cell lung cancer KRAS_G12A PAK7 89 126 Age:overall -0.43 -3.34 1.92 1263.79 1.00 3227 86 123 3 FALSE 0.13
non-small cell lung cancer KRAS_G12A STAG2 25 38 50-65yrs 0.71 -0.64 1.68 1269.93 1.00 1258 24 37 1 TRUE 0.68
non-small cell lung cancer KRAS_G12A STAG2 63 61 >65yrs 0.90 0.00 1.74 1358.60 1.00 2010 58 56 5 TRUE 1.47
non-small cell lung cancer KRAS_G12A STAG2 88 99 Age:overall 0.79 -0.44 1.81 1475.01 1.00 3268 82 93 6 TRUE 0.81
colorectal cancer KRAS_G12A BRCA2 14 38 40-50yrs -0.70 -2.29 0.60 1262.94 1.00 414 14 38 0 TRUE 0.48
colorectal cancer KRAS_G12A BRCA2 16 61 50-65yrs -0.73 -2.37 0.46 1260.19 1.00 912 16 61 0 TRUE 0.49
colorectal cancer KRAS_G12A BRCA2 18 65 >65yrs -0.39 -1.76 0.78 1316.55 1.00 581 15 62 3 TRUE 0.25
non-small cell lung cancer KRAS_G12A BRCA2 25 58 50-65yrs -0.57 -3.84 0.93 1137.89 1.00 1235 25 58 0 TRUE 0.18
non-small cell lung cancer KRAS_G12A BRCA2 63 72 >65yrs 0.27 -1.03 1.24 1203.95 1.00 2006 59 68 4 TRUE 0.20
colorectal cancer KRAS_G12A BRCA2 53 190 Age:overall -0.61 -2.05 0.53 1228.78 1.00 2107 50 187 3 TRUE 0.45
non-small cell lung cancer KRAS_G12A BRCA2 88 130 Age:overall -0.14 -2.56 1.37 1347.55 1.00 3241 84 126 4 TRUE 0.05
colorectal cancer KRAS_G12A NOTCH3 14 28 40-50yrs -0.14 -1.51 0.98 1337.30 1.00 412 14 28 0 TRUE 0.08
colorectal cancer KRAS_G12A NOTCH3 16 71 50-65yrs 0.04 -1.12 1.05 1356.73 1.00 898 14 69 2 TRUE 0.02
colorectal cancer KRAS_G12A NOTCH3 16 79 >65yrs 0.08 -1.00 1.08 1433.05 1.00 574 13 76 3 TRUE 0.06
non-small cell lung cancer KRAS_G12A NOTCH3 25 44 50-65yrs -0.57 -3.33 0.89 894.27 1.00 1249 25 44 0 TRUE 0.21
non-small cell lung cancer KRAS_G12A NOTCH3 63 78 >65yrs -0.13 -1.50 0.96 1204.09 1.00 1996 60 75 3 TRUE 0.08
colorectal cancer KRAS_G12A NOTCH3 51 200 Age:overall -0.04 -1.16 0.97 1374.02 1.00 2080 46 195 5 TRUE 0.03
non-small cell lung cancer KRAS_G12A NOTCH3 88 122 Age:overall -0.32 -2.31 1.13 1074.01 1.00 3245 85 119 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A NOTCH4 25 49 50-65yrs -0.33 -1.98 1.04 995.30 1.00 1239 24 48 1 TRUE 0.18
non-small cell lung cancer KRAS_G12A NOTCH4 63 84 >65yrs -0.35 -1.97 0.80 892.87 1.00 1979 61 82 2 TRUE 0.21
non-small cell lung cancer KRAS_G12A NOTCH4 88 133 Age:overall -0.33 -2.02 1.08 971.13 1.00 3218 85 130 3 TRUE 0.17
colorectal cancer KRAS_G12A FGFR3 18 25 50-65yrs -0.73 -4.23 1.38 1315.09 1.00 1033 18 25 0 TRUE 0.20
colorectal cancer KRAS_G12A FGFR3 18 24 >65yrs -0.36 -3.00 1.56 1394.90 1.00 682 17 23 1 TRUE 0.12
colorectal cancer KRAS_G12A FGFR3 36 49 Age:overall -0.52 -3.60 1.50 1279.00 1.00 1715 35 48 1 TRUE 0.16
non-small cell lung cancer KRAS_G12A MAP3K13 25 21 50-65yrs -0.99 -4.32 1.12 1148.66 1.00 1263 25 21 0 FALSE 0.32
non-small cell lung cancer KRAS_G12A MAP3K13 63 30 >65yrs -0.75 -3.58 1.07 1006.50 1.00 2030 62 29 1 FALSE 0.28
non-small cell lung cancer KRAS_G12A MAP3K13 88 51 Age:overall -0.86 -3.96 1.27 1099.65 1.00 3293 87 50 1 FALSE 0.28
colorectal cancer KRAS_G12A IGF1R 14 11 40-50yrs -1.18 -3.98 0.80 859.47 1.00 426 14 11 0 TRUE 0.47
colorectal cancer KRAS_G12A IGF1R 16 25 50-65yrs -1.05 -3.73 0.90 887.29 1.00 930 15 24 1 TRUE 0.42
colorectal cancer KRAS_G12A IGF1R 16 33 >65yrs -1.21 -4.11 0.69 1068.02 1.00 604 16 33 0 TRUE 0.49
non-small cell lung cancer KRAS_G12A IGF1R 25 29 50-65yrs -4.70 -12.29 -0.12 231.34 1.01 1261 25 29 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A IGF1R 63 23 >65yrs -4.68 -12.16 -0.06 265.73 1.01 2043 63 23 0 TRUE 0.81
colorectal cancer KRAS_G12A IGF1R 51 80 Age:overall -1.15 -3.88 0.75 866.02 1.00 2164 50 79 1 TRUE 0.47
non-small cell lung cancer KRAS_G12A IGF1R 88 52 Age:overall -4.59 -11.91 0.03 218.98 1.02 3304 88 52 0 TRUE 0.84
non-small cell lung cancer KRAS_G12A KEAP1 25 203 50-65yrs 0.20 -0.64 0.95 1385.71 1.00 1101 20 198 5 FALSE 0.21
non-small cell lung cancer KRAS_G12A KEAP1 64 312 >65yrs 0.20 -0.44 0.77 1075.80 1.00 1777 53 301 11 FALSE 0.28
non-small cell lung cancer KRAS_G12A KEAP1 89 537 Age:overall 0.17 -0.85 1.09 1203.17 1.00 3047 73 521 16 FALSE 0.13
colorectal cancer KRAS_G12A KDM5C 16 24 50-65yrs -3.78 -11.46 0.29 21.67 1.08 930 16 24 0 FALSE 0.62
colorectal cancer KRAS_G12A KDM5C 16 26 >65yrs -3.76 -11.35 0.11 18.88 1.08 611 16 26 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A KDM5C 25 43 50-65yrs -0.46 -2.40 1.08 1294.14 1.00 1251 24 42 1 FALSE 0.22
non-small cell lung cancer KRAS_G12A KDM5C 63 59 >65yrs -0.59 -2.45 0.79 1247.26 1.00 2009 62 58 1 FALSE 0.31
colorectal cancer KRAS_G12A KDM5C 32 50 Age:overall -3.73 -11.16 0.27 17.78 1.09 1541 32 50 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A KDM5C 88 102 Age:overall -0.51 -2.58 1.00 1304.24 1.00 3260 86 100 2 FALSE 0.24
non-small cell lung cancer KRAS_G12A CDKN2A 27 114 50-65yrs -0.01 -1.16 1.04 1087.11 1.00 1244 24 111 3 TRUE 0.00
non-small cell lung cancer KRAS_G12A CDKN2A 65 141 >65yrs -0.30 -1.38 0.57 1214.13 1.00 1986 62 138 3 TRUE 0.26
non-small cell lung cancer KRAS_G12A CDKN2A 92 273 Age:overall -0.18 -1.61 1.06 1303.61 1.00 3416 86 267 6 TRUE 0.10
colorectal cancer KRAS_G12A EPHB1 16 31 50-65yrs -4.68 -11.96 -0.33 965.16 1.01 921 16 31 0 FALSE 0.90
colorectal cancer KRAS_G12A EPHB1 16 28 >65yrs -4.68 -11.87 -0.20 972.09 1.01 607 16 28 0 FALSE 0.90
non-small cell lung cancer KRAS_G12A EPHB1 26 54 50-65yrs 0.35 -0.82 1.57 189.71 1.02 1247 23 51 3 FALSE 0.23
non-small cell lung cancer KRAS_G12A EPHB1 63 99 >65yrs -0.06 -1.28 0.95 471.01 1.01 1973 61 97 2 FALSE 0.03
colorectal cancer KRAS_G12A EPHB1 37 72 Age:overall -4.68 -11.95 -0.26 980.92 1.01 1728 37 72 0 FALSE 0.91
non-small cell lung cancer KRAS_G12A EPHB1 89 153 Age:overall 0.17 -1.13 1.61 418.31 1.01 3220 84 148 5 FALSE 0.09
colorectal cancer KRAS_G12A IRS2 14 19 40-50yrs -1.39 -3.79 0.67 83.82 1.05 419 14 19 0 FALSE 0.59
colorectal cancer KRAS_G12A IRS2 16 30 50-65yrs -1.38 -3.79 0.67 78.96 1.05 925 16 30 0 FALSE 0.59
colorectal cancer KRAS_G12A IRS2 16 25 >65yrs -1.28 -3.71 0.78 71.47 1.05 612 15 24 1 FALSE 0.53
non-small cell lung cancer KRAS_G12A IRS2 25 25 50-65yrs -1.49 -5.00 0.88 1209.62 1.00 1265 25 25 0 FALSE 0.48
non-small cell lung cancer KRAS_G12A IRS2 63 55 >65yrs -1.25 -4.20 0.67 1309.55 1.00 2014 62 54 1 FALSE 0.49
colorectal cancer KRAS_G12A IRS2 51 87 Age:overall -1.36 -3.80 0.63 74.15 1.05 2156 50 86 1 FALSE 0.59
non-small cell lung cancer KRAS_G12A IRS2 88 80 Age:overall -1.33 -4.64 0.85 1241.22 1.00 3279 87 79 1 FALSE 0.48
colorectal cancer KRAS_G12A FANCA 14 11 40-50yrs -4.21 -10.75 -0.18 903.49 1.01 426 14 11 0 TRUE 1.03
colorectal cancer KRAS_G12A FANCA 16 31 50-65yrs -4.22 -10.73 -0.19 893.29 1.01 926 16 31 0 TRUE 1.04
colorectal cancer KRAS_G12A FANCA 16 12 >65yrs -4.20 -10.57 -0.18 902.11 1.01 621 16 12 0 TRUE 1.04
non-small cell lung cancer KRAS_G12A FANCA 25 29 50-65yrs -5.11 -11.46 -0.35 111.55 1.03 1261 25 29 0 TRUE 1.01
non-small cell lung cancer KRAS_G12A FANCA 63 36 >65yrs -5.08 -11.65 -0.39 116.35 1.03 2031 63 36 0 TRUE 1.00
colorectal cancer KRAS_G12A FANCA 51 65 Age:overall -4.21 -10.66 -0.31 888.36 1.01 2174 51 65 0 TRUE 1.05
non-small cell lung cancer KRAS_G12A FANCA 88 65 Age:overall -5.02 -11.37 -0.43 118.68 1.03 3292 88 65 0 TRUE 1.00
non-small cell lung cancer KRAS_G12A IL7R 25 38 50-65yrs -0.75 -3.25 0.94 1089.40 1.00 1257 25 38 0 FALSE 0.28
non-small cell lung cancer KRAS_G12A IL7R 63 49 >65yrs -0.29 -2.26 1.11 849.87 1.00 2022 61 47 2 FALSE 0.14
non-small cell lung cancer KRAS_G12A IL7R 88 87 Age:overall -0.54 -2.81 1.15 1183.35 1.00 3279 86 85 2 FALSE 0.22
colorectal cancer KRAS_G12A ERBB3 14 14 40-50yrs -0.65 -2.63 0.96 772.41 1.00 424 14 14 0 TRUE 0.33
colorectal cancer KRAS_G12A ERBB3 16 48 50-65yrs -0.58 -2.55 0.99 684.48 1.00 908 15 47 1 TRUE 0.29
colorectal cancer KRAS_G12A ERBB3 16 47 >65yrs -0.59 -2.62 0.94 731.77 1.00 594 15 46 1 TRUE 0.29
colorectal cancer KRAS_G12A ERBB3 51 122 Age:overall -0.63 -2.60 0.91 674.28 1.00 2127 49 120 2 TRUE 0.32
colorectal cancer KRAS_G12A SMAD4 15 68 40-50yrs -0.18 -1.14 0.65 570.15 1.00 413 12 65 3 TRUE 0.16
colorectal cancer KRAS_G12A SMAD4 18 151 50-65yrs -0.18 -1.14 0.66 590.63 1.00 917 14 147 4 TRUE 0.16
colorectal cancer KRAS_G12A SMAD4 18 108 >65yrs -0.27 -1.34 0.54 515.51 1.00 608 18 108 0 TRUE 0.25
non-small cell lung cancer KRAS_G12A SMAD4 26 45 50-65yrs -0.92 -3.94 0.77 1108.38 1.00 1306 26 45 0 TRUE 0.33
non-small cell lung cancer KRAS_G12A SMAD4 65 64 >65yrs -0.48 -2.35 0.82 1143.16 1.00 2056 63 62 2 TRUE 0.25
colorectal cancer KRAS_G12A SMAD4 56 360 Age:overall -0.22 -1.16 0.56 548.43 1.00 2139 49 353 7 TRUE 0.20
non-small cell lung cancer KRAS_G12A SMAD4 91 109 Age:overall -0.67 -2.77 0.96 1329.09 1.00 3362 89 107 2 TRUE 0.31
colorectal cancer KRAS_G12A ATM 15 33 40-50yrs -0.08 -1.19 0.92 1305.97 1.00 445 15 33 0 TRUE 0.05
colorectal cancer KRAS_G12A ATM 18 87 50-65yrs 0.04 -0.97 0.98 1280.62 1.00 989 16 85 2 TRUE 0.03
colorectal cancer KRAS_G12A ATM 20 87 >65yrs 0.13 -0.88 1.04 1288.86 1.00 637 16 83 4 TRUE 0.10
non-small cell lung cancer KRAS_G12A ATM 26 100 50-65yrs 0.06 -1.91 1.25 1447.32 1.00 1258 25 99 1 TRUE 0.02
non-small cell lung cancer KRAS_G12A ATM 69 179 >65yrs 1.15 0.52 1.73 1490.83 1.00 1974 53 163 16 TRUE 3.77
colorectal cancer KRAS_G12A ATM 58 231 Age:overall 0.02 -1.00 0.88 1218.96 1.00 2287 52 225 6 TRUE 0.01
non-small cell lung cancer KRAS_G12A ATM 95 279 Age:overall 0.57 -1.44 1.94 1435.08 1.00 3232 78 262 17 TRUE 0.31
colorectal cancer KRAS_G12A RB1 15 15 40-50yrs -4.58 -11.18 -0.15 728.46 1.00 457 15 15 0 TRUE 0.89
colorectal cancer KRAS_G12A RB1 18 20 50-65yrs -4.57 -11.23 -0.12 749.97 1.00 1041 18 20 0 TRUE 0.89
colorectal cancer KRAS_G12A RB1 18 24 >65yrs -4.58 -11.18 -0.01 716.06 1.00 683 18 24 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A RB1 26 82 50-65yrs -1.50 -4.27 0.06 1230.16 1.00 1267 26 82 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A RB1 65 131 >65yrs -1.20 -3.02 0.08 1305.11 1.00 1992 63 129 2 TRUE 0.92
colorectal cancer KRAS_G12A RB1 51 59 Age:overall -4.57 -11.22 -0.11 737.73 1.00 2181 51 59 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A RB1 91 213 Age:overall -1.36 -3.65 0.18 1305.67 1.00 3259 89 211 2 TRUE 0.77
colorectal cancer KRAS_G12A KMT2D 6 41 <40yrs -0.66 -2.11 0.68 1446.85 1.00 187 4 39 2 FALSE 0.46
colorectal cancer KRAS_G12A KMT2D 14 52 40-50yrs -1.10 -2.63 0.11 1429.91 1.00 402 14 52 0 FALSE 0.94
colorectal cancer KRAS_G12A KMT2D 16 122 50-65yrs -0.97 -2.33 0.25 1395.86 1.00 870 15 121 1 FALSE 0.85
colorectal cancer KRAS_G12A KMT2D 16 173 >65yrs -1.09 -2.43 -0.03 1523.05 1.00 541 15 172 1 FALSE 1.12
non-small cell lung cancer KRAS_G12A KMT2D 25 130 50-65yrs -1.29 -5.16 0.23 1153.39 1.00 1182 25 130 0 FALSE 0.42
non-small cell lung cancer KRAS_G12A KMT2D 64 188 >65yrs -0.23 -1.26 0.64 1457.78 1.00 1906 58 182 6 FALSE 0.20
colorectal cancer KRAS_G12A KMT2D 52 388 Age:overall -0.94 -2.23 0.14 1427.70 1.00 2000 48 384 4 FALSE 0.95
non-small cell lung cancer KRAS_G12A KMT2D 89 318 Age:overall -0.71 -3.10 0.90 1071.09 1.00 3088 83 312 6 FALSE 0.32
colorectal cancer KRAS_G12A TSC2 14 19 40-50yrs 0.00 -1.86 1.31 1082.06 1.00 419 14 19 0 TRUE 0.00
colorectal cancer KRAS_G12A TSC2 17 36 50-65yrs 0.71 -0.68 2.10 339.05 1.01 924 13 32 4 TRUE 0.49
colorectal cancer KRAS_G12A TSC2 16 46 >65yrs -0.14 -2.13 1.19 1339.10 1.00 598 16 46 0 TRUE 0.06
non-small cell lung cancer KRAS_G12A TSC2 26 23 50-65yrs 0.91 -0.44 2.24 1364.25 1.00 1270 24 21 2 TRUE 0.75
non-small cell lung cancer KRAS_G12A TSC2 63 44 >65yrs 0.65 -0.60 1.68 1332.18 1.00 2025 61 42 2 TRUE 0.56
colorectal cancer KRAS_G12A TSC2 52 115 Age:overall 0.17 -1.30 1.33 923.78 1.00 2141 48 111 4 TRUE 0.09
non-small cell lung cancer KRAS_G12A TSC2 89 67 Age:overall 0.78 -0.58 2.12 1360.21 1.00 3295 85 63 4 TRUE 0.55
colorectal cancer KRAS_G12A APC 8 246 <40yrs 0.22 -0.34 0.86 1257.67 1.00 89 0 238 8 TRUE 0.33
colorectal cancer KRAS_G12A APC 17 494 40-50yrs 0.18 -0.36 0.82 966.43 1.00 162 7 484 10 TRUE 0.26
colorectal cancer KRAS_G12A APC 24 1094 50-65yrs 0.16 -0.40 0.77 1233.88 1.00 365 5 1075 19 TRUE 0.23
colorectal cancer KRAS_G12A APC 25 704 >65yrs 0.22 -0.32 0.84 1167.12 1.00 258 5 684 20 TRUE 0.34
non-small cell lung cancer KRAS_G12A APC 26 60 50-65yrs -0.45 -3.50 0.98 833.95 1.00 1291 26 60 0 TRUE 0.15
non-small cell lung cancer KRAS_G12A APC 65 87 >65yrs 0.34 -0.85 1.30 1066.50 1.00 2041 60 82 5 TRUE 0.29
colorectal cancer KRAS_G12A APC 74 2538 Age:overall 0.20 -0.32 0.82 1161.54 1.00 874 17 2481 57 TRUE 0.30
non-small cell lung cancer KRAS_G12A APC 91 147 Age:overall -0.06 -2.31 1.29 1063.47 1.00 3332 86 142 5 TRUE 0.02
colorectal cancer KRAS_G12A ERBB2 15 13 40-50yrs -4.73 -11.88 -0.54 1193.53 1.00 457 15 13 0 TRUE 1.01
colorectal cancer KRAS_G12A ERBB2 18 49 50-65yrs -4.74 -11.88 -0.58 1224.31 1.00 1013 18 49 0 TRUE 1.01
colorectal cancer KRAS_G12A ERBB2 18 29 >65yrs -4.72 -11.89 -0.51 1224.08 1.00 676 18 29 0 TRUE 1.01
non-small cell lung cancer KRAS_G12A ERBB2 26 53 50-65yrs -5.19 -11.90 -0.70 199.37 1.01 1296 26 53 0 TRUE 1.05
non-small cell lung cancer KRAS_G12A ERBB2 65 68 >65yrs -5.20 -11.59 -0.92 192.99 1.01 2053 65 68 0 TRUE 1.08
colorectal cancer KRAS_G12A ERBB2 56 104 Age:overall -4.72 -11.96 -0.58 1190.25 1.00 2364 56 104 0 TRUE 1.02
non-small cell lung cancer KRAS_G12A ERBB2 91 121 Age:overall -5.09 -11.64 -0.75 194.83 1.01 3349 91 121 0 TRUE 1.05
colorectal cancer KRAS_G12A JAK1 14 13 40-50yrs -0.23 -2.27 1.29 961.06 1.00 426 14 13 0 TRUE 0.10
colorectal cancer KRAS_G12A JAK1 16 20 50-65yrs -0.25 -2.40 1.23 1198.86 1.00 933 16 20 0 TRUE 0.10
colorectal cancer KRAS_G12A JAK1 16 26 >65yrs -0.09 -1.92 1.39 984.96 1.00 611 15 25 1 TRUE 0.04
non-small cell lung cancer KRAS_G12A JAK1 25 15 50-65yrs 0.34 -1.59 2.00 953.95 1.01 1276 24 14 1 TRUE 0.15
non-small cell lung cancer KRAS_G12A JAK1 63 34 >65yrs 0.13 -1.78 1.52 409.32 1.01 2035 62 33 1 TRUE 0.06
colorectal cancer KRAS_G12A JAK1 51 75 Age:overall -0.13 -1.99 1.32 968.63 1.00 2174 49 73 2 TRUE 0.06
non-small cell lung cancer KRAS_G12A JAK1 88 49 Age:overall 0.23 -1.74 1.79 589.77 1.01 3311 86 47 2 TRUE 0.09
colorectal cancer KRAS_G12A ARID2 14 21 40-50yrs -0.65 -2.96 1.08 880.41 1.00 418 14 21 0 FALSE 0.27
colorectal cancer KRAS_G12A ARID2 16 36 50-65yrs -0.21 -2.07 1.50 335.24 1.00 923 14 34 2 FALSE 0.09
colorectal cancer KRAS_G12A ARID2 16 44 >65yrs -0.71 -2.91 0.89 1053.23 1.00 593 16 44 0 FALSE 0.30
non-small cell lung cancer KRAS_G12A ARID2 25 71 50-65yrs 0.10 -1.11 1.15 943.87 1.00 1224 23 69 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A ARID2 63 105 >65yrs -0.01 -1.18 0.90 992.62 1.00 1974 60 102 3 FALSE 0.00
colorectal cancer KRAS_G12A ARID2 46 101 Age:overall -0.52 -2.37 1.06 460.23 1.01 1934 44 99 2 FALSE 0.24
non-small cell lung cancer KRAS_G12A ARID2 88 176 Age:overall 0.05 -1.30 1.23 1157.30 1.00 3198 83 171 5 FALSE 0.03
non-small cell lung cancer KRAS_G12A SOX17 25 26 50-65yrs -1.08 -4.51 1.00 1117.22 1.00 1259 25 26 0 FALSE 0.34
non-small cell lung cancer KRAS_G12A SOX17 63 32 >65yrs -0.80 -3.80 1.04 1373.36 1.00 2028 62 31 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A SOX17 88 58 Age:overall -0.90 -4.03 1.13 1206.65 1.00 3287 87 57 1 FALSE 0.31
colorectal cancer KRAS_G12A MTOR 14 26 40-50yrs -1.35 -3.90 0.12 40.47 1.08 416 13 25 1 TRUE 0.68
colorectal cancer KRAS_G12A MTOR 16 54 50-65yrs -1.38 -4.01 0.01 39.43 1.08 904 16 54 0 TRUE 0.69
colorectal cancer KRAS_G12A MTOR 16 45 >65yrs -1.38 -3.94 0.04 41.26 1.08 594 16 45 0 TRUE 0.70
non-small cell lung cancer KRAS_G12A MTOR 25 39 50-65yrs -1.24 -3.01 0.63 4.31 1.24 1252 25 39 0 TRUE 0.61
non-small cell lung cancer KRAS_G12A MTOR 63 70 >65yrs -1.07 -2.13 0.66 2.48 1.55 1999 61 68 2 TRUE 0.59
colorectal cancer KRAS_G12A MTOR 51 140 Age:overall -1.37 -3.94 0.04 41.15 1.08 2115 50 139 1 TRUE 0.69
non-small cell lung cancer KRAS_G12A MTOR 88 109 Age:overall -1.15 -2.53 0.68 3.20 1.35 3251 86 107 2 TRUE 0.60
non-small cell lung cancer KRAS_G12A RFWD2 25 25 50-65yrs 0.17 -1.79 1.77 873.85 1.00 1260 24 24 1 FALSE 0.07
non-small cell lung cancer KRAS_G12A RFWD2 63 31 >65yrs 0.00 -1.94 1.41 1013.44 1.00 2028 62 30 1 FALSE 0.00
non-small cell lung cancer KRAS_G12A RFWD2 88 56 Age:overall 0.08 -1.95 1.66 1014.64 1.00 3288 86 54 2 FALSE 0.03
non-small cell lung cancer KRAS_G12A IRS1 25 28 50-65yrs -1.27 -4.98 0.88 1343.32 1.00 1256 25 28 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A IRS1 63 42 >65yrs -1.00 -3.77 0.80 919.01 1.00 2020 62 41 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A IRS1 88 70 Age:overall -1.09 -4.19 0.94 1034.78 1.00 3276 87 69 1 FALSE 0.39
colorectal cancer KRAS_G12A NOTCH1 15 27 40-50yrs -0.54 -2.21 0.75 1421.56 1.00 450 15 27 0 TRUE 0.33
colorectal cancer KRAS_G12A NOTCH1 19 55 50-65yrs -0.28 -1.77 0.98 1461.35 1.00 1013 17 53 2 TRUE 0.16
colorectal cancer KRAS_G12A NOTCH1 18 72 >65yrs -0.60 -2.20 0.69 1073.54 1.00 649 18 72 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A NOTCH1 26 45 50-65yrs 0.49 -0.70 1.57 1221.02 1.00 1305 24 43 2 TRUE 0.40
non-small cell lung cancer KRAS_G12A NOTCH1 65 77 >65yrs 0.36 -0.73 1.22 1019.24 1.00 2048 62 74 3 TRUE 0.33
colorectal cancer KRAS_G12A NOTCH1 57 172 Age:overall -0.44 -1.92 0.72 1417.32 1.00 2331 54 169 3 TRUE 0.29
non-small cell lung cancer KRAS_G12A NOTCH1 91 122 Age:overall 0.43 -0.87 1.55 1322.77 1.00 3353 86 117 5 TRUE 0.32
colorectal cancer KRAS_G12A NTRK1 16 19 50-65yrs 1.36 0.06 2.63 1091.17 1.00 934 14 17 2 TRUE 1.41
colorectal cancer KRAS_G12A NTRK1 16 26 >65yrs 1.03 -0.42 2.25 909.41 1.00 610 15 25 1 TRUE 0.87
non-small cell lung cancer KRAS_G12A NTRK1 25 35 50-65yrs 0.67 -0.67 1.78 1359.92 1.00 1259 23 33 2 TRUE 0.52
non-small cell lung cancer KRAS_G12A NTRK1 63 46 >65yrs 0.49 -0.90 1.53 1269.70 1.00 2021 61 44 2 TRUE 0.37
colorectal cancer KRAS_G12A NTRK1 37 57 Age:overall 1.18 -0.16 2.41 925.66 1.00 1747 33 53 4 TRUE 1.13
non-small cell lung cancer KRAS_G12A NTRK1 88 81 Age:overall 0.59 -0.88 1.89 1310.65 1.00 3280 84 77 4 TRUE 0.40
non-small cell lung cancer KRAS_G12A INPP4A 25 21 50-65yrs -0.47 -3.31 1.60 1328.71 1.00 1264 24 20 1 FALSE 0.15
non-small cell lung cancer KRAS_G12A INPP4A 63 29 >65yrs -1.06 -4.80 1.03 1078.61 1.00 2029 63 29 0 FALSE 0.33
non-small cell lung cancer KRAS_G12A INPP4A 88 50 Age:overall -0.73 -3.87 1.49 1429.99 1.00 3293 87 49 1 FALSE 0.23
colorectal cancer KRAS_G12A SETD2 14 15 40-50yrs -0.64 -2.50 0.96 362.98 1.01 424 14 15 0 FALSE 0.31
colorectal cancer KRAS_G12A SETD2 16 49 50-65yrs -0.68 -2.54 0.89 458.12 1.01 912 16 49 0 FALSE 0.34
colorectal cancer KRAS_G12A SETD2 16 29 >65yrs -0.52 -2.39 1.04 340.44 1.01 609 15 28 1 FALSE 0.24
non-small cell lung cancer KRAS_G12A SETD2 25 82 50-65yrs -0.74 -4.05 0.70 968.72 1.00 1220 25 82 0 FALSE 0.26
non-small cell lung cancer KRAS_G12A SETD2 64 132 >65yrs 0.12 -0.78 0.96 1031.15 1.00 1960 58 126 6 FALSE 0.10
colorectal cancer KRAS_G12A SETD2 51 113 Age:overall -0.58 -2.41 0.92 331.04 1.01 2143 49 111 2 FALSE 0.29
non-small cell lung cancer KRAS_G12A SETD2 89 214 Age:overall -0.30 -2.44 1.04 1336.00 1.00 3180 83 208 6 FALSE 0.13
colorectal cancer KRAS_G12A PBRM1 14 21 40-50yrs -4.71 -11.69 -0.46 1023.74 1.00 418 14 21 0 TRUE 0.97
colorectal cancer KRAS_G12A PBRM1 16 32 50-65yrs -4.71 -11.73 -0.30 1033.88 1.00 925 16 32 0 TRUE 0.96
colorectal cancer KRAS_G12A PBRM1 16 31 >65yrs -4.73 -11.88 -0.42 1020.60 1.00 604 16 31 0 TRUE 0.97
non-small cell lung cancer KRAS_G12A PBRM1 25 37 50-65yrs -0.53 -3.58 1.02 1248.92 1.00 1259 25 37 0 TRUE 0.19
non-small cell lung cancer KRAS_G12A PBRM1 63 71 >65yrs -0.05 -1.43 1.07 1264.09 1.00 2005 60 68 3 TRUE 0.03
colorectal cancer KRAS_G12A PBRM1 46 84 Age:overall -4.71 -11.54 -0.38 1016.80 1.00 1947 46 84 0 TRUE 0.98
non-small cell lung cancer KRAS_G12A PBRM1 88 108 Age:overall -0.29 -2.45 1.17 1274.87 1.00 3264 85 105 3 TRUE 0.12
colorectal cancer KRAS_G12A EPHA3 14 15 40-50yrs -0.09 -1.64 1.16 1611.31 1.00 424 14 15 0 FALSE 0.04
colorectal cancer KRAS_G12A EPHA3 16 39 50-65yrs 0.17 -1.33 1.49 1430.97 1.00 915 14 37 2 FALSE 0.09
colorectal cancer KRAS_G12A EPHA3 16 45 >65yrs -0.14 -1.71 1.09 1440.13 1.00 593 16 45 0 FALSE 0.07
non-small cell lung cancer KRAS_G12A EPHA3 25 103 50-65yrs 0.12 -1.20 1.14 1252.77 1.00 1201 23 101 2 FALSE 0.08
non-small cell lung cancer KRAS_G12A EPHA3 64 126 >65yrs 0.37 -0.52 1.16 1448.59 1.00 1951 58 120 6 FALSE 0.41
colorectal cancer KRAS_G12A EPHA3 51 113 Age:overall 0.01 -1.40 1.20 1616.56 1.00 2134 48 110 3 FALSE 0.01
non-small cell lung cancer KRAS_G12A EPHA3 89 240 Age:overall 0.21 -1.17 1.40 1335.00 1.00 3334 81 232 8 FALSE 0.12
colorectal cancer KRAS_G12A KIT 15 13 40-50yrs -4.60 -13.65 0.35 92.03 1.01 458 15 13 0 TRUE 0.81
colorectal cancer KRAS_G12A KIT 18 20 50-65yrs -4.59 -13.60 0.32 90.01 1.01 1038 18 20 0 TRUE 0.81
colorectal cancer KRAS_G12A KIT 18 17 >65yrs -4.61 -13.57 0.28 91.50 1.01 687 18 17 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A KIT 26 25 50-65yrs -4.60 -12.04 -0.16 1143.53 1.00 1322 26 25 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A KIT 65 52 >65yrs -4.70 -11.88 -0.42 1216.48 1.00 2069 65 52 0 TRUE 0.94
colorectal cancer KRAS_G12A KIT 51 50 Age:overall -4.60 -13.62 0.36 90.99 1.01 2183 51 50 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A KIT 91 77 Age:overall -4.58 -11.32 -0.20 1246.21 1.00 3391 91 77 0 TRUE 0.92
colorectal cancer KRAS_G12A KDR 18 29 50-65yrs -0.86 -3.54 1.19 133.41 1.04 1030 17 28 1 TRUE 0.32
colorectal cancer KRAS_G12A KDR 18 26 >65yrs -0.96 -3.60 1.03 223.59 1.03 683 18 26 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A KDR 26 58 50-65yrs -0.52 -5.01 1.11 1256.96 1.00 1294 26 58 0 TRUE 0.12
non-small cell lung cancer KRAS_G12A KDR 65 88 >65yrs 0.61 -0.40 1.48 1258.56 1.00 2038 59 82 6 TRUE 0.71
colorectal cancer KRAS_G12A KDR 41 66 Age:overall -0.93 -3.55 1.01 155.04 1.04 1936 40 65 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A KDR 91 146 Age:overall 0.06 -2.85 1.58 1298.25 1.00 3332 85 140 6 TRUE 0.02
colorectal cancer KRAS_G12A RICTOR 14 13 40-50yrs -0.99 -4.08 1.14 956.99 1.00 427 14 13 0 FALSE 0.35
colorectal cancer KRAS_G12A RICTOR 16 24 50-65yrs -0.99 -4.09 1.06 863.89 1.00 929 16 24 0 FALSE 0.36
colorectal cancer KRAS_G12A RICTOR 16 25 >65yrs -0.86 -3.82 1.18 1036.88 1.00 613 15 24 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A RICTOR 25 24 50-65yrs -1.18 -4.52 0.93 1074.70 1.00 1266 25 24 0 FALSE 0.38
non-small cell lung cancer KRAS_G12A RICTOR 63 37 >65yrs -0.91 -3.70 0.95 878.18 1.00 2031 62 36 1 FALSE 0.36
colorectal cancer KRAS_G12A RICTOR 46 62 Age:overall -0.93 -3.82 1.12 933.30 1.00 1969 45 61 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A RICTOR 88 61 Age:overall -1.02 -4.04 1.00 1064.51 1.00 3297 87 60 1 FALSE 0.36
colorectal cancer KRAS_G12A RAD50 14 13 40-50yrs -1.08 -3.60 1.07 161.98 1.02 425 14 13 0 FALSE 0.43
colorectal cancer KRAS_G12A RAD50 16 22 50-65yrs -0.97 -3.33 1.18 112.22 1.03 932 15 21 1 FALSE 0.38
colorectal cancer KRAS_G12A RAD50 16 20 >65yrs -1.10 -3.49 0.97 152.67 1.02 616 16 20 0 FALSE 0.45
colorectal cancer KRAS_G12A RAD50 46 55 Age:overall -1.06 -3.43 1.01 137.07 1.02 1973 45 54 1 FALSE 0.44
colorectal cancer KRAS_G12A CSF1R 15 15 40-50yrs 0.16 -2.06 1.63 937.85 1.01 458 15 15 0 TRUE 0.06
colorectal cancer KRAS_G12A CSF1R 19 21 50-65yrs 0.45 -1.37 1.93 1073.11 1.01 1039 17 19 2 TRUE 0.22
colorectal cancer KRAS_G12A CSF1R 18 15 >65yrs 0.17 -2.08 1.64 806.30 1.01 689 18 15 0 TRUE 0.07
non-small cell lung cancer KRAS_G12A CSF1R 26 22 50-65yrs 0.41 -1.33 1.83 1420.91 1.00 1328 25 21 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A CSF1R 65 45 >65yrs 0.36 -1.19 1.53 1324.05 1.00 2076 63 43 2 TRUE 0.22
colorectal cancer KRAS_G12A CSF1R 52 51 Age:overall 0.26 -1.62 1.69 880.72 1.01 2186 50 49 2 TRUE 0.12
non-small cell lung cancer KRAS_G12A CSF1R 91 67 Age:overall 0.36 -1.38 1.80 1233.77 1.00 3404 88 64 3 TRUE 0.17
non-small cell lung cancer KRAS_G12A PARK2 25 27 50-65yrs -1.21 -4.50 0.95 1412.80 1.00 1263 25 27 0 FALSE 0.41
non-small cell lung cancer KRAS_G12A PARK2 63 36 >65yrs -0.93 -3.69 0.95 1229.38 1.00 2030 62 35 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A PARK2 88 63 Age:overall -1.06 -4.08 0.91 1459.86 1.00 3293 87 62 1 FALSE 0.39
non-small cell lung cancer KRAS_G12A NTRK2 25 24 50-65yrs 0.78 -0.86 2.20 1391.06 1.00 1269 23 22 2 FALSE 0.50
non-small cell lung cancer KRAS_G12A NTRK2 63 39 >65yrs 0.27 -1.54 1.53 1256.86 1.00 2031 62 38 1 FALSE 0.13
non-small cell lung cancer KRAS_G12A NTRK2 88 63 Age:overall 0.51 -1.24 1.95 1387.04 1.00 3300 85 60 3 FALSE 0.26
colorectal cancer KRAS_G12A PTCH1 14 21 40-50yrs -1.80 -4.28 0.12 268.87 1.00 418 14 21 0 TRUE 0.90
colorectal cancer KRAS_G12A PTCH1 16 53 50-65yrs -1.70 -4.14 0.20 236.18 1.00 916 15 52 1 TRUE 0.85
colorectal cancer KRAS_G12A PTCH1 16 55 >65yrs -1.80 -4.29 0.04 264.41 1.00 587 16 55 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A PTCH1 25 21 50-65yrs -4.33 -10.64 0.00 1191.63 1.00 1269 25 21 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A PTCH1 63 35 >65yrs -4.43 -11.11 -0.16 1095.39 1.00 2030 63 35 0 TRUE 0.93
colorectal cancer KRAS_G12A PTCH1 51 145 Age:overall -1.77 -4.34 0.07 252.90 1.00 2122 50 144 1 TRUE 0.91
non-small cell lung cancer KRAS_G12A PTCH1 88 56 Age:overall -4.32 -10.56 -0.08 1114.96 1.00 3299 88 56 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A TET1 25 35 50-65yrs 0.33 -1.28 1.53 1185.86 1.00 1254 24 34 1 FALSE 0.19
non-small cell lung cancer KRAS_G12A TET1 64 82 >65yrs 0.44 -0.64 1.32 1578.03 1.00 1987 60 78 4 FALSE 0.42
non-small cell lung cancer KRAS_G12A TET1 89 117 Age:overall 0.39 -1.11 1.60 1489.60 1.00 3241 84 112 5 FALSE 0.23
colorectal cancer KRAS_G12A FGFR2 15 14 40-50yrs -0.76 -3.93 1.28 1219.08 1.00 457 15 14 0 TRUE 0.24
colorectal cancer KRAS_G12A FGFR2 18 15 50-65yrs -0.48 -3.51 1.54 1212.87 1.00 1042 17 14 1 TRUE 0.15
colorectal cancer KRAS_G12A FGFR2 18 17 >65yrs -0.71 -3.83 1.38 1341.63 1.00 687 18 17 0 TRUE 0.23
colorectal cancer KRAS_G12A FGFR2 51 46 Age:overall -0.65 -3.62 1.31 1300.21 1.00 2186 50 45 1 TRUE 0.22
colorectal cancer KRAS_G12A TBX3 14 13 40-50yrs -1.02 -3.98 0.89 1124.92 1.00 426 14 13 0 FALSE 0.38
colorectal cancer KRAS_G12A TBX3 16 30 50-65yrs -1.02 -3.93 0.86 1195.49 1.00 924 16 30 0 FALSE 0.38
colorectal cancer KRAS_G12A TBX3 16 30 >65yrs -0.90 -3.68 0.95 1128.47 1.00 610 15 29 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A TBX3 25 58 50-65yrs -0.80 -3.77 0.79 1013.89 1.00 1239 25 58 0 FALSE 0.29
non-small cell lung cancer KRAS_G12A TBX3 63 74 >65yrs -0.19 -1.69 0.94 1155.47 1.00 1996 60 71 3 FALSE 0.11
colorectal cancer KRAS_G12A TBX3 46 73 Age:overall -0.98 -3.83 0.88 1111.99 1.00 1960 45 72 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A TBX3 88 132 Age:overall -0.45 -2.63 1.24 1309.20 1.00 3235 85 129 3 FALSE 0.20
colorectal cancer KRAS_G12A HNF1A 18 25 50-65yrs -4.17 -11.28 0.31 1404.13 1.00 1033 18 25 0 TRUE 0.75
colorectal cancer KRAS_G12A HNF1A 18 19 >65yrs -4.21 -11.36 0.38 1422.12 1.00 684 18 19 0 TRUE 0.77
colorectal cancer KRAS_G12A HNF1A 36 44 Age:overall -4.14 -11.09 0.44 1405.48 1.00 1717 36 44 0 TRUE 0.77
colorectal cancer KRAS_G12A DICER1 14 19 40-50yrs -4.60 -12.05 -0.33 986.39 1.00 421 14 19 0 TRUE 0.92
colorectal cancer KRAS_G12A DICER1 16 23 50-65yrs -4.59 -11.99 -0.34 995.29 1.00 932 16 23 0 TRUE 0.93
colorectal cancer KRAS_G12A DICER1 16 23 >65yrs -4.60 -12.02 -0.39 945.65 1.00 613 16 23 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A DICER1 25 26 50-65yrs -4.52 -11.75 -0.32 750.91 1.00 1264 25 26 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A DICER1 63 59 >65yrs -4.61 -12.08 -0.55 598.12 1.00 2011 63 59 0 TRUE 0.92
colorectal cancer KRAS_G12A DICER1 51 76 Age:overall -4.60 -12.04 -0.46 963.91 1.00 2171 51 76 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A DICER1 88 85 Age:overall -4.48 -11.53 -0.46 651.31 1.00 3275 88 85 0 TRUE 0.92
colorectal cancer KRAS_G12A SMAD3 16 33 40-50yrs 0.80 -0.33 1.84 1393.52 1.00 412 13 30 3 TRUE 0.81
colorectal cancer KRAS_G12A SMAD3 17 44 50-65yrs 0.72 -0.46 1.84 1440.92 1.00 914 15 42 2 TRUE 0.67
colorectal cancer KRAS_G12A SMAD3 16 23 >65yrs 0.43 -1.22 1.65 1273.12 1.00 611 16 23 0 TRUE 0.25
colorectal cancer KRAS_G12A SMAD3 49 100 Age:overall 0.66 -0.58 1.72 1174.98 1.00 1937 44 95 5 TRUE 0.58
colorectal cancer KRAS_G12A NTRK3 14 16 40-50yrs -0.87 -3.72 0.98 664.70 1.00 426 13 15 1 FALSE 0.33
colorectal cancer KRAS_G12A NTRK3 16 21 50-65yrs -0.96 -3.77 0.92 628.77 1.00 931 16 21 0 FALSE 0.37
colorectal cancer KRAS_G12A NTRK3 16 22 >65yrs -0.99 -3.86 0.85 699.36 1.00 613 16 22 0 FALSE 0.38
non-small cell lung cancer KRAS_G12A NTRK3 27 64 50-65yrs 0.63 -0.50 1.76 1370.74 1.00 1234 23 60 4 FALSE 0.57
non-small cell lung cancer KRAS_G12A NTRK3 63 134 >65yrs 0.02 -1.12 0.92 1315.52 1.00 1952 60 131 3 FALSE 0.01
colorectal cancer KRAS_G12A NTRK3 51 70 Age:overall -0.95 -3.76 0.86 626.91 1.00 2172 50 69 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A NTRK3 90 198 Age:overall 0.31 -1.03 1.63 1549.92 1.00 3186 83 191 7 FALSE 0.20
colorectal cancer KRAS_G12A AXIN1 16 22 50-65yrs -4.61 -11.87 0.39 1189.85 1.00 932 16 22 0 FALSE 0.81
colorectal cancer KRAS_G12A AXIN1 16 37 >65yrs -4.71 -11.76 -0.02 1167.34 1.00 601 16 37 0 FALSE 0.87
colorectal cancer KRAS_G12A AXIN1 32 59 Age:overall -4.49 -11.36 0.36 1170.32 1.00 1533 32 59 0 FALSE 0.85
colorectal cancer KRAS_G12A GRIN2A 14 29 40-50yrs -0.84 -2.47 0.60 251.16 1.02 414 14 29 0 FALSE 0.51
colorectal cancer KRAS_G12A GRIN2A 16 50 50-65yrs -0.84 -2.57 0.55 244.36 1.01 902 16 50 0 FALSE 0.51
colorectal cancer KRAS_G12A GRIN2A 17 42 >65yrs -0.76 -2.44 0.70 225.61 1.02 597 15 40 2 FALSE 0.43
non-small cell lung cancer KRAS_G12A GRIN2A 25 70 50-65yrs -1.69 -4.53 0.38 1320.27 1.00 1226 24 69 1 FALSE 0.74
non-small cell lung cancer KRAS_G12A GRIN2A 63 110 >65yrs -2.32 -5.72 -0.35 960.52 1.00 1961 63 110 0 FALSE 1.00
colorectal cancer KRAS_G12A GRIN2A 52 136 Age:overall -0.81 -2.43 0.60 221.62 1.02 2112 50 134 2 FALSE 0.49
non-small cell lung cancer KRAS_G12A GRIN2A 88 191 Age:overall -1.97 -4.82 0.08 1281.87 1.00 3368 87 190 1 FALSE 0.88
colorectal cancer KRAS_G12A PALB2 16 18 50-65yrs -0.70 -3.74 1.37 1422.85 1.00 934 16 18 0 TRUE 0.22
colorectal cancer KRAS_G12A PALB2 16 20 >65yrs -0.74 -3.82 1.35 1450.78 1.00 615 16 20 0 TRUE 0.25
non-small cell lung cancer KRAS_G12A PALB2 25 30 50-65yrs -1.24 -4.63 0.88 814.60 1.00 1263 25 30 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A PALB2 63 29 >65yrs -0.82 -3.70 1.10 1012.48 1.00 2037 62 28 1 TRUE 0.29
colorectal cancer KRAS_G12A PALB2 37 51 Age:overall -0.58 -3.47 1.46 1381.99 1.00 1751 36 50 1 TRUE 0.19
non-small cell lung cancer KRAS_G12A PALB2 88 59 Age:overall -0.99 -4.22 1.19 690.46 1.00 3300 87 58 1 TRUE 0.32
colorectal cancer KRAS_G12A CTCF 14 20 40-50yrs -4.59 -11.15 -0.26 937.48 1.00 420 14 20 0 FALSE 1.08
colorectal cancer KRAS_G12A CTCF 16 30 50-65yrs -4.58 -11.14 -0.35 900.55 1.01 924 16 30 0 FALSE 1.08
colorectal cancer KRAS_G12A CTCF 16 32 >65yrs -4.56 -11.12 -0.24 940.94 1.00 606 16 32 0 FALSE 1.09
colorectal cancer KRAS_G12A CTCF 46 82 Age:overall -4.58 -11.07 -0.30 931.22 1.00 1950 46 82 0 FALSE 1.10
colorectal cancer KRAS_G12A CDH1 18 22 50-65yrs -0.11 -2.67 1.89 1172.47 1.00 1038 17 21 1 TRUE 0.03
colorectal cancer KRAS_G12A CDH1 18 18 >65yrs -0.50 -3.79 1.59 1135.51 1.00 689 18 18 0 TRUE 0.14
colorectal cancer KRAS_G12A CDH1 36 40 Age:overall -0.29 -3.01 1.83 1200.16 1.00 1727 35 39 1 TRUE 0.08
colorectal cancer KRAS_G12A CDK12 14 13 40-50yrs -0.25 -2.34 1.26 1506.21 1.00 424 14 13 0 FALSE 0.10
colorectal cancer KRAS_G12A CDK12 16 39 50-65yrs -0.27 -2.35 1.24 1476.70 1.00 917 16 39 0 FALSE 0.12
colorectal cancer KRAS_G12A CDK12 17 28 >65yrs -0.05 -2.00 1.37 1416.98 1.00 613 15 26 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A CDK12 25 15 50-65yrs -1.10 -5.06 1.15 774.64 1.00 1275 25 15 0 FALSE 0.31
non-small cell lung cancer KRAS_G12A CDK12 63 42 >65yrs -0.83 -3.65 0.91 723.94 1.00 2026 62 41 1 FALSE 0.31
colorectal cancer KRAS_G12A CDK12 47 80 Age:overall -0.20 -2.10 1.26 1540.78 1.00 1954 45 78 2 FALSE 0.09
non-small cell lung cancer KRAS_G12A CDK12 88 57 Age:overall -0.92 -4.02 1.29 580.97 1.00 3301 87 56 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A STK11 26 196 50-65yrs 0.68 -0.05 1.42 1439.38 1.00 1165 19 189 7 TRUE 1.13
non-small cell lung cancer KRAS_G12A STK11 66 326 >65yrs 0.58 0.00 1.11 1153.31 1.00 1818 51 311 15 TRUE 1.32
non-small cell lung cancer KRAS_G12A STK11 92 541 Age:overall 0.57 -0.64 1.62 1411.55 1.00 3165 70 519 22 TRUE 0.49
colorectal cancer KRAS_G12A BRD4 16 40 50-65yrs -1.06 -4.33 0.94 854.13 1.00 916 16 40 0 FALSE 0.35
colorectal cancer KRAS_G12A BRD4 16 33 >65yrs -0.80 -3.77 1.16 992.58 1.00 603 15 32 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A BRD4 25 15 50-65yrs -4.82 -12.18 0.06 91.79 1.03 1275 25 15 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A BRD4 63 37 >65yrs -4.87 -12.30 -0.19 86.82 1.03 2030 63 37 0 FALSE 0.88
colorectal cancer KRAS_G12A BRD4 32 73 Age:overall -0.91 -4.09 1.05 958.22 1.00 1519 31 72 1 FALSE 0.32
non-small cell lung cancer KRAS_G12A BRD4 88 52 Age:overall -4.77 -12.02 -0.03 81.96 1.03 3305 88 52 0 FALSE 0.87
colorectal cancer KRAS_G12A ASXL1 14 21 40-50yrs -1.44 -4.48 0.53 549.53 1.01 417 14 21 0 TRUE 0.59
colorectal cancer KRAS_G12A ASXL1 16 40 50-65yrs -1.29 -4.00 0.64 572.97 1.00 914 15 39 1 TRUE 0.53
colorectal cancer KRAS_G12A ASXL1 16 40 >65yrs -1.43 -4.22 0.48 478.49 1.01 599 16 40 0 TRUE 0.60
non-small cell lung cancer KRAS_G12A ASXL1 25 29 50-65yrs -1.32 -4.50 0.82 561.48 1.01 1261 25 29 0 TRUE 0.47
non-small cell lung cancer KRAS_G12A ASXL1 63 53 >65yrs -1.11 -3.94 0.80 589.53 1.00 2027 62 52 1 TRUE 0.45
colorectal cancer KRAS_G12A ASXL1 46 101 Age:overall -1.38 -4.18 0.53 539.83 1.01 1930 45 100 1 TRUE 0.59
non-small cell lung cancer KRAS_G12A ASXL1 88 82 Age:overall -1.20 -4.23 0.87 519.54 1.00 3288 87 81 1 TRUE 0.44
colorectal cancer KRAS_G12A EP300 14 16 40-50yrs 0.11 -1.39 1.34 1371.51 1.00 422 14 16 0 TRUE 0.06
colorectal cancer KRAS_G12A EP300 16 38 50-65yrs 0.22 -1.20 1.34 1488.32 1.00 922 15 37 1 TRUE 0.13
colorectal cancer KRAS_G12A EP300 16 56 >65yrs 0.26 -1.01 1.28 1450.00 1.00 591 14 54 2 TRUE 0.18
non-small cell lung cancer KRAS_G12A EP300 25 30 50-65yrs 0.76 -0.52 2.04 1260.82 1.00 1264 23 28 2 TRUE 0.61
non-small cell lung cancer KRAS_G12A EP300 63 74 >65yrs 0.45 -0.67 1.42 1340.42 1.00 2003 60 71 3 TRUE 0.39
colorectal cancer KRAS_G12A EP300 51 125 Age:overall 0.22 -1.05 1.23 1393.75 1.00 2136 47 121 4 TRUE 0.14
non-small cell lung cancer KRAS_G12A EP300 88 104 Age:overall 0.59 -0.89 2.00 1477.26 1.00 3267 83 99 5 TRUE 0.36
colorectal cancer KRAS_G12A ERBB4 15 20 40-50yrs 0.11 -1.29 1.22 1016.58 1.00 453 15 20 0 TRUE 0.06
colorectal cancer KRAS_G12A ERBB4 19 60 50-65yrs 0.24 -1.01 1.33 1235.84 1.00 1006 16 57 3 TRUE 0.16
colorectal cancer KRAS_G12A ERBB4 18 41 >65yrs 0.10 -1.28 1.17 1041.90 1.00 665 18 41 0 TRUE 0.05
non-small cell lung cancer KRAS_G12A ERBB4 28 80 50-65yrs 0.53 -0.47 1.55 1292.56 1.00 1283 24 76 4 TRUE 0.52
non-small cell lung cancer KRAS_G12A ERBB4 65 105 >65yrs 0.20 -0.84 1.00 1207.04 1.00 2030 62 102 3 TRUE 0.18
colorectal cancer KRAS_G12A ERBB4 57 138 Age:overall 0.16 -1.17 1.16 1083.27 1.00 2344 53 134 4 TRUE 0.10
non-small cell lung cancer KRAS_G12A ERBB4 93 185 Age:overall 0.36 -0.85 1.47 1369.30 1.00 3313 86 178 7 TRUE 0.27
non-small cell lung cancer KRAS_G12A MDC1 25 36 50-65yrs -1.10 -4.11 1.01 1184.96 1.00 1250 24 35 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A MDC1 63 53 >65yrs -1.58 -4.95 0.40 1099.83 1.00 2014 63 53 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A MDC1 88 89 Age:overall -1.31 -4.34 0.74 1095.00 1.00 3264 87 88 1 FALSE 0.50
non-small cell lung cancer KRAS_G12A RECQL4 25 25 50-65yrs -4.53 -11.30 -0.13 1335.74 1.00 1259 25 25 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A RECQL4 63 35 >65yrs -4.54 -11.14 -0.24 1381.49 1.00 2026 63 35 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A RECQL4 88 60 Age:overall -4.47 -11.13 -0.04 1352.33 1.00 3285 88 60 0 TRUE 0.90
colorectal cancer KRAS_G12A MED12 14 18 40-50yrs -4.84 -11.76 -0.50 565.23 1.01 419 14 18 0 TRUE 0.99
colorectal cancer KRAS_G12A MED12 16 35 50-65yrs -4.83 -11.76 -0.46 556.26 1.01 924 16 35 0 TRUE 1.00
colorectal cancer KRAS_G12A MED12 16 42 >65yrs -4.84 -11.71 -0.63 569.24 1.01 596 16 42 0 TRUE 1.00
non-small cell lung cancer KRAS_G12A MED12 25 64 50-65yrs -0.34 -3.77 0.93 80.61 1.04 1233 25 64 0 TRUE 0.10
non-small cell lung cancer KRAS_G12A MED12 63 104 >65yrs 0.40 -0.58 1.24 293.24 1.01 1973 57 98 6 TRUE 0.44
colorectal cancer KRAS_G12A MED12 51 108 Age:overall -4.83 -11.77 -0.60 562.22 1.01 2140 51 108 0 TRUE 1.00
non-small cell lung cancer KRAS_G12A MED12 88 168 Age:overall 0.06 -2.29 1.24 461.89 1.02 3206 82 162 6 TRUE 0.02
non-small cell lung cancer KRAS_G12A ERCC5 25 28 50-65yrs -0.73 -3.50 1.26 105.75 1.02 1258 24 27 1 TRUE 0.24
non-small cell lung cancer KRAS_G12A ERCC5 63 43 >65yrs -1.20 -4.60 1.10 72.47 1.03 2020 63 43 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A ERCC5 88 71 Age:overall -0.96 -3.88 1.09 81.52 1.02 3278 87 70 1 TRUE 0.32
colorectal cancer KRAS_G12A BRCA1 14 15 40-50yrs -1.30 -4.21 0.83 1240.12 1.00 423 14 15 0 TRUE 0.51
colorectal cancer KRAS_G12A BRCA1 16 19 50-65yrs -1.28 -4.40 0.89 1291.12 1.00 933 16 19 0 TRUE 0.49
colorectal cancer KRAS_G12A BRCA1 16 26 >65yrs -1.33 -4.19 0.66 1257.92 1.00 611 16 26 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A BRCA1 26 32 50-65yrs 0.86 -0.50 2.28 1162.63 1.00 1261 23 29 3 TRUE 0.66
non-small cell lung cancer KRAS_G12A BRCA1 63 61 >65yrs 0.03 -1.89 1.25 1124.21 1.00 2009 62 60 1 TRUE 0.01
colorectal cancer KRAS_G12A BRCA1 51 79 Age:overall -1.20 -3.98 0.69 1172.05 1.00 2169 50 78 1 TRUE 0.50
non-small cell lung cancer KRAS_G12A BRCA1 89 93 Age:overall 0.47 -1.08 1.90 1412.01 1.00 3270 85 89 4 TRUE 0.27
colorectal cancer KRAS_G12A RBM10 16 38 50-65yrs -4.52 -11.37 -0.01 518.44 1.00 915 16 38 0 FALSE 0.87
colorectal cancer KRAS_G12A RBM10 16 22 >65yrs -4.51 -11.23 0.07 499.91 1.00 615 16 22 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A RBM10 25 106 50-65yrs 0.78 -0.21 1.62 1453.54 1.00 1197 21 102 4 FALSE 1.04
non-small cell lung cancer KRAS_G12A RBM10 63 265 >65yrs 0.90 0.32 1.44 1450.07 1.00 1826 47 249 16 FALSE 2.87
colorectal cancer KRAS_G12A RBM10 32 60 Age:overall -4.42 -11.01 0.16 519.52 1.00 1530 32 60 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A RBM10 88 382 Age:overall 0.79 -0.57 2.01 1530.74 1.00 3204 68 362 20 FALSE 0.69
colorectal cancer KRAS_G12A TSC1 16 23 50-65yrs -3.84 -10.87 -0.10 107.46 1.03 931 16 23 0 TRUE 0.78
colorectal cancer KRAS_G12A TSC1 16 27 >65yrs -3.87 -10.84 -0.14 116.27 1.03 611 16 27 0 TRUE 0.78
non-small cell lung cancer KRAS_G12A TSC1 25 23 50-65yrs 1.35 -0.01 2.70 916.06 1.00 1271 22 20 3 TRUE 1.28
non-small cell lung cancer KRAS_G12A TSC1 63 33 >65yrs 0.66 -1.02 1.82 1065.19 1.00 2033 62 32 1 TRUE 0.44
colorectal cancer KRAS_G12A TSC1 32 50 Age:overall -3.79 -10.36 0.06 122.29 1.03 1542 32 50 0 TRUE 0.78
non-small cell lung cancer KRAS_G12A TSC1 88 56 Age:overall 0.99 -0.72 2.54 1511.28 1.00 3304 84 52 4 TRUE 0.63
colorectal cancer KRAS_G12A FLCN 16 23 50-65yrs 0.17 -3.55 2.03 1108.01 1.00 933 16 23 0 TRUE 0.04
colorectal cancer KRAS_G12A FLCN 16 19 >65yrs 0.83 -1.17 2.36 1210.71 1.00 616 14 17 2 TRUE 0.43
colorectal cancer KRAS_G12A FLCN 32 42 Age:overall 0.50 -1.86 2.23 1094.85 1.00 1549 30 40 2 TRUE 0.18
colorectal cancer KRAS_G12A NF1 6 23 <40yrs 0.16 -1.44 1.81 1202.36 1.00 199 3 20 3 TRUE 0.08
colorectal cancer KRAS_G12A NF1 14 21 40-50yrs -0.37 -2.22 0.96 1003.07 1.00 423 14 21 0 TRUE 0.19
colorectal cancer KRAS_G12A NF1 16 58 50-65yrs -0.42 -2.29 0.92 1025.78 1.00 902 16 58 0 TRUE 0.21
colorectal cancer KRAS_G12A NF1 16 40 >65yrs -0.43 -2.36 0.90 1163.47 1.00 604 16 40 0 TRUE 0.21
non-small cell lung cancer KRAS_G12A NF1 25 110 50-65yrs -1.17 -2.87 0.25 1361.38 1.00 1197 24 109 1 TRUE 0.84
non-small cell lung cancer KRAS_G12A NF1 63 191 >65yrs -1.22 -2.79 -0.07 1330.43 1.00 1903 61 189 2 TRUE 1.12
colorectal cancer KRAS_G12A NF1 52 142 Age:overall -0.27 -1.80 0.99 1106.17 1.00 2128 49 139 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A NF1 88 313 Age:overall -1.21 -3.04 0.31 1311.32 1.00 3281 85 310 3 TRUE 0.85
colorectal cancer KRAS_G12A FLT1 14 13 40-50yrs -4.60 -11.36 -0.32 856.91 1.00 426 14 13 0 FALSE 1.03
colorectal cancer KRAS_G12A FLT1 16 40 50-65yrs -4.60 -11.21 -0.35 1058.95 1.00 918 16 40 0 FALSE 1.03
colorectal cancer KRAS_G12A FLT1 16 25 >65yrs -4.61 -11.34 -0.40 832.37 1.00 613 16 25 0 FALSE 1.05
non-small cell lung cancer KRAS_G12A FLT1 26 51 50-65yrs 0.72 -0.31 2.02 23.40 1.16 1247 22 47 4 FALSE 0.54
non-small cell lung cancer KRAS_G12A FLT1 63 80 >65yrs -0.16 -1.89 0.93 838.13 1.00 1993 62 79 1 FALSE 0.08
colorectal cancer KRAS_G12A FLT1 46 78 Age:overall -4.60 -11.15 -0.36 908.66 1.00 1957 46 78 0 FALSE 1.04
non-small cell lung cancer KRAS_G12A FLT1 89 131 Age:overall 0.27 -1.20 1.89 612.37 1.02 3240 84 126 5 FALSE 0.13
colorectal cancer KRAS_G12A RPTOR 14 16 40-50yrs -0.83 -3.85 1.04 705.81 1.01 423 14 16 0 FALSE 0.31
colorectal cancer KRAS_G12A RPTOR 16 23 50-65yrs -0.68 -3.54 1.23 830.63 1.00 930 15 22 1 FALSE 0.24
colorectal cancer KRAS_G12A RPTOR 16 24 >65yrs -0.84 -3.78 1.06 605.09 1.01 612 16 24 0 FALSE 0.31
non-small cell lung cancer KRAS_G12A RPTOR 25 22 50-65yrs -1.23 -4.66 0.93 1068.44 1.00 1268 25 22 0 FALSE 0.40
non-small cell lung cancer KRAS_G12A RPTOR 63 40 >65yrs -1.01 -4.01 0.90 1290.07 1.00 2027 62 39 1 FALSE 0.40
colorectal cancer KRAS_G12A RPTOR 46 63 Age:overall -0.77 -3.56 1.05 684.42 1.01 1965 45 62 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A RPTOR 88 62 Age:overall -1.12 -4.29 0.97 1104.99 1.00 3295 87 61 1 FALSE 0.41
colorectal cancer KRAS_G12A RASA1 14 21 40-50yrs 0.12 -2.44 1.68 967.49 1.00 421 14 21 0 FALSE 0.04
colorectal cancer KRAS_G12A RASA1 16 24 50-65yrs 0.16 -2.46 1.68 844.16 1.00 933 16 24 0 FALSE 0.06
colorectal cancer KRAS_G12A RASA1 18 20 >65yrs 0.86 -0.80 2.31 1053.49 1.00 619 15 17 3 FALSE 0.54
non-small cell lung cancer KRAS_G12A RASA1 25 26 50-65yrs -4.96 -12.15 -0.41 568.01 1.00 1264 25 26 0 FALSE 0.95
non-small cell lung cancer KRAS_G12A RASA1 63 67 >65yrs -5.01 -11.94 -0.67 622.23 1.00 2000 63 67 0 FALSE 1.01
colorectal cancer KRAS_G12A RASA1 48 65 Age:overall 0.39 -1.55 1.80 1064.78 1.00 1973 45 62 3 FALSE 0.19
non-small cell lung cancer KRAS_G12A RASA1 88 93 Age:overall -4.89 -11.88 -0.24 584.74 1.00 3264 88 93 0 FALSE 0.97
colorectal cancer KRAS_G12A EPHA5 14 27 40-50yrs -0.85 -2.94 0.65 1148.90 1.00 418 14 27 0 FALSE 0.44
colorectal cancer KRAS_G12A EPHA5 16 46 50-65yrs -0.87 -3.01 0.60 992.54 1.00 911 16 46 0 FALSE 0.47
colorectal cancer KRAS_G12A EPHA5 16 54 >65yrs -0.87 -2.82 0.51 1177.97 1.00 587 16 54 0 FALSE 0.48
non-small cell lung cancer KRAS_G12A EPHA5 26 99 50-65yrs -0.17 -1.36 0.95 673.98 1.00 1206 23 96 3 FALSE 0.11
non-small cell lung cancer KRAS_G12A EPHA5 63 151 >65yrs -0.53 -1.86 0.38 1019.61 1.00 1927 61 149 2 FALSE 0.47
colorectal cancer KRAS_G12A EPHA5 51 144 Age:overall -0.76 -2.60 0.62 1063.29 1.00 2116 49 142 2 FALSE 0.43
non-small cell lung cancer KRAS_G12A EPHA5 89 250 Age:overall -0.35 -1.67 0.84 1225.60 1.00 3133 84 245 5 FALSE 0.22
colorectal cancer KRAS_G12A AR 14 22 40-50yrs -1.22 -3.97 0.76 1332.33 1.00 418 13 21 1 TRUE 0.49
colorectal cancer KRAS_G12A AR 16 38 50-65yrs -1.47 -4.41 0.53 1310.15 1.00 914 16 38 0 TRUE 0.60
colorectal cancer KRAS_G12A AR 16 48 >65yrs -1.52 -4.46 0.54 1390.00 1.00 592 16 48 0 TRUE 0.65
non-small cell lung cancer KRAS_G12A AR 25 48 50-65yrs -0.47 -2.48 1.05 1561.63 1.00 1249 24 47 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A AR 63 55 >65yrs -0.60 -2.51 0.82 1523.12 1.00 2014 62 54 1 TRUE 0.31
colorectal cancer KRAS_G12A AR 46 108 Age:overall -1.41 -4.23 0.57 1364.67 1.00 1924 45 107 1 TRUE 0.61
non-small cell lung cancer KRAS_G12A AR 88 103 Age:overall -0.54 -2.69 1.06 1516.10 1.00 3263 86 101 2 TRUE 0.24
colorectal cancer KRAS_G12A GNAS 15 16 40-50yrs -0.04 -1.88 1.45 863.15 1.00 454 14 15 1 TRUE 0.02
colorectal cancer KRAS_G12A GNAS 18 29 50-65yrs -0.04 -1.88 1.38 802.34 1.00 1031 17 28 1 TRUE 0.02
colorectal cancer KRAS_G12A GNAS 18 25 >65yrs -0.14 -2.06 1.27 834.71 1.00 680 18 25 0 TRUE 0.06
colorectal cancer KRAS_G12A GNAS 51 70 Age:overall -0.08 -1.95 1.39 825.15 1.00 2165 49 68 2 TRUE 0.03
colorectal cancer KRAS_G12A ASXL2 14 16 40-50yrs -4.55 -12.03 -0.09 867.58 1.00 427 14 16 0 FALSE 0.85
colorectal cancer KRAS_G12A ASXL2 16 26 50-65yrs -4.58 -12.02 -0.08 846.35 1.00 931 16 26 0 FALSE 0.86
colorectal cancer KRAS_G12A ASXL2 16 20 >65yrs -4.55 -11.90 -0.15 866.74 1.00 616 16 20 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A ASXL2 25 22 50-65yrs -0.64 -3.45 1.60 1365.95 1.00 1269 24 21 1 FALSE 0.21
non-small cell lung cancer KRAS_G12A ASXL2 63 36 >65yrs -1.19 -4.61 0.87 1315.80 1.00 2032 63 36 0 FALSE 0.39
colorectal cancer KRAS_G12A ASXL2 46 62 Age:overall -4.55 -11.91 -0.10 835.56 1.00 1974 46 62 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A ASXL2 88 58 Age:overall -0.88 -3.78 1.35 1356.31 1.00 3301 87 57 1 FALSE 0.30
colorectal cancer KRAS_G12A SF3B1 14 16 40-50yrs -0.90 -3.82 1.04 940.29 1.00 424 14 16 0 TRUE 0.33
colorectal cancer KRAS_G12A SF3B1 16 24 50-65yrs -0.91 -3.75 0.97 846.33 1.00 931 16 24 0 TRUE 0.34
colorectal cancer KRAS_G12A SF3B1 16 24 >65yrs -0.76 -3.56 1.14 883.65 1.00 617 15 23 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A SF3B1 25 36 50-65yrs 1.16 -0.03 2.27 1423.43 1.00 1257 22 33 3 TRUE 1.35
non-small cell lung cancer KRAS_G12A SF3B1 64 49 >65yrs 0.91 -0.19 1.84 849.53 1.00 2023 61 46 3 TRUE 1.10
colorectal cancer KRAS_G12A SF3B1 46 64 Age:overall -0.86 -3.65 0.95 816.22 1.00 1972 45 63 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A SF3B1 89 85 Age:overall 1.04 -0.21 2.25 1081.75 1.00 3280 83 79 6 TRUE 0.99
colorectal cancer KRAS_G12A MLH1 18 25 50-65yrs -4.27 -11.32 0.50 783.36 1.00 1035 18 25 0 TRUE 0.75
colorectal cancer KRAS_G12A MLH1 18 12 >65yrs -4.30 -11.46 0.53 801.38 1.00 693 18 12 0 TRUE 0.75
colorectal cancer KRAS_G12A MLH1 36 37 Age:overall -4.21 -11.35 0.56 753.06 1.00 1728 36 37 0 TRUE 0.75
colorectal cancer KRAS_G12A ROS1 14 19 40-50yrs -4.58 -11.25 -0.38 495.48 1.01 420 14 19 0 TRUE 0.93
colorectal cancer KRAS_G12A ROS1 16 43 50-65yrs -4.60 -11.39 -0.43 497.49 1.01 917 16 43 0 TRUE 0.93
colorectal cancer KRAS_G12A ROS1 16 31 >65yrs -4.59 -11.29 -0.44 491.88 1.00 607 16 31 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A ROS1 25 37 50-65yrs -0.36 -3.10 1.08 821.17 1.01 1253 25 37 0 TRUE 0.12
non-small cell lung cancer KRAS_G12A ROS1 63 66 >65yrs 0.08 -1.25 1.18 1297.74 1.00 2007 60 63 3 TRUE 0.05
colorectal cancer KRAS_G12A ROS1 46 93 Age:overall -4.58 -11.15 -0.45 494.22 1.00 1944 46 93 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A ROS1 88 103 Age:overall -0.13 -2.18 1.29 1104.85 1.00 3260 85 100 3 TRUE 0.06
colorectal cancer KRAS_G12A PIK3R2 14 11 40-50yrs -0.68 -4.04 1.38 1095.38 1.00 427 14 11 0 FALSE 0.21
colorectal cancer KRAS_G12A PIK3R2 16 13 50-65yrs -0.33 -3.31 1.86 808.61 1.00 939 15 12 1 FALSE 0.10
colorectal cancer KRAS_G12A PIK3R2 16 21 >65yrs -0.69 -3.71 1.40 1033.50 1.00 614 16 21 0 FALSE 0.23
colorectal cancer KRAS_G12A PIK3R2 46 45 Age:overall -0.57 -3.58 1.42 892.48 1.00 1980 45 44 1 FALSE 0.19
colorectal cancer KRAS_G12A FLT3 18 17 50-65yrs -4.10 -11.59 0.57 655.37 1.00 1041 18 17 0 TRUE 0.73
colorectal cancer KRAS_G12A FLT3 18 17 >65yrs -4.18 -11.77 0.68 701.15 1.00 687 18 17 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A FLT3 26 31 50-65yrs -0.17 -2.14 1.41 1213.42 1.00 1320 25 30 1 TRUE 0.07
non-small cell lung cancer KRAS_G12A FLT3 65 44 >65yrs -0.32 -2.25 1.13 1128.36 1.00 2077 64 43 1 TRUE 0.15
colorectal cancer KRAS_G12A FLT3 36 34 Age:overall -4.08 -11.63 0.66 671.63 1.00 1728 36 34 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A FLT3 91 75 Age:overall -0.23 -2.34 1.51 1212.02 1.00 3397 89 73 2 TRUE 0.09
colorectal cancer KRAS_G12A MSH2 14 24 40-50yrs -4.50 -11.30 -0.37 873.46 1.00 422 14 24 0 TRUE 0.93
colorectal cancer KRAS_G12A MSH2 16 26 50-65yrs -4.47 -11.38 -0.29 857.05 1.00 929 16 26 0 TRUE 0.92
colorectal cancer KRAS_G12A MSH2 16 23 >65yrs -4.49 -11.40 -0.28 859.25 1.00 617 16 23 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A MSH2 25 18 50-65yrs -4.52 -11.51 -0.02 1411.50 1.00 1273 25 18 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A MSH2 63 37 >65yrs -4.64 -11.46 -0.25 1401.76 1.00 2031 63 37 0 TRUE 0.90
colorectal cancer KRAS_G12A MSH2 46 73 Age:overall -4.48 -11.31 -0.38 844.15 1.00 1968 46 73 0 TRUE 0.94
non-small cell lung cancer KRAS_G12A MSH2 88 55 Age:overall -4.49 -11.19 0.00 1400.66 1.00 3304 88 55 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A DIS3 25 27 50-65yrs 0.49 -1.10 1.74 1020.68 1.00 1264 24 26 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A DIS3 63 34 >65yrs 0.52 -0.97 1.63 1169.01 1.00 2035 61 32 2 FALSE 0.37
non-small cell lung cancer KRAS_G12A DIS3 88 61 Age:overall 0.52 -1.08 1.91 1068.70 1.00 3299 85 58 3 FALSE 0.30
colorectal cancer KRAS_G12A AXL 14 16 40-50yrs -1.09 -3.69 0.77 1321.68 1.00 425 13 15 1 FALSE 0.47
colorectal cancer KRAS_G12A AXL 16 30 50-65yrs -1.18 -3.95 0.58 1291.14 1.00 926 16 30 0 FALSE 0.51
colorectal cancer KRAS_G12A AXL 16 29 >65yrs -1.18 -3.92 0.69 1210.16 1.00 607 16 29 0 FALSE 0.51
colorectal cancer KRAS_G12A AXL 51 88 Age:overall -1.16 -3.91 0.67 1229.64 1.00 2160 50 87 1 FALSE 0.51
colorectal cancer KRAS_G12A PIK3CG 14 22 40-50yrs -0.51 -2.43 1.02 772.99 1.00 419 14 22 0 FALSE 0.24
colorectal cancer KRAS_G12A PIK3CG 16 37 50-65yrs -0.38 -2.38 1.11 669.21 1.00 921 15 36 1 FALSE 0.17
colorectal cancer KRAS_G12A PIK3CG 16 42 >65yrs -0.41 -2.30 1.04 769.85 1.00 595 15 41 1 FALSE 0.19
non-small cell lung cancer KRAS_G12A PIK3CG 25 69 50-65yrs -0.74 -5.04 0.87 1162.33 1.00 1227 25 69 0 FALSE 0.19
non-small cell lung cancer KRAS_G12A PIK3CG 64 105 >65yrs 0.42 -0.50 1.29 1418.88 1.00 1978 58 99 6 FALSE 0.44
colorectal cancer KRAS_G12A PIK3CG 46 101 Age:overall -0.43 -2.33 1.03 763.59 1.00 1935 44 99 2 FALSE 0.21
non-small cell lung cancer KRAS_G12A PIK3CG 89 174 Age:overall -0.14 -2.82 1.29 1217.27 1.00 3205 83 168 6 FALSE 0.05
colorectal cancer KRAS_G12A MAP2K4 14 11 40-50yrs -0.63 -3.56 1.30 693.87 1.01 426 13 10 1 TRUE 0.22
colorectal cancer KRAS_G12A MAP2K4 16 29 50-65yrs -0.76 -3.61 1.03 491.73 1.02 924 16 29 0 TRUE 0.28
colorectal cancer KRAS_G12A MAP2K4 16 18 >65yrs -0.75 -3.74 1.13 582.79 1.01 616 16 18 0 TRUE 0.27
colorectal cancer KRAS_G12A MAP2K4 46 58 Age:overall -0.71 -3.59 1.18 624.52 1.01 1966 45 57 1 TRUE 0.26
colorectal cancer KRAS_G12A EGFR 15 12 40-50yrs -4.64 -11.89 -0.16 381.92 1.00 458 15 12 0 TRUE 0.86
colorectal cancer KRAS_G12A EGFR 18 27 50-65yrs -4.64 -12.02 -0.14 371.12 1.00 1031 18 27 0 TRUE 0.86
colorectal cancer KRAS_G12A EGFR 18 23 >65yrs -4.65 -11.87 -0.04 367.98 1.00 683 18 23 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A EGFR 26 403 50-65yrs -3.92 -6.89 -2.00 964.43 1.00 1007 26 403 0 TRUE 2.86
non-small cell lung cancer KRAS_G12A EGFR 65 550 >65yrs -3.77 -6.35 -2.07 915.09 1.00 1675 64 549 1 TRUE 3.13
colorectal cancer KRAS_G12A EGFR 51 62 Age:overall -4.64 -11.91 -0.20 374.28 1.00 2172 51 62 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A EGFR 91 1042 Age:overall -3.82 -6.33 -2.04 1067.32 1.00 2876 90 1041 1 TRUE 3.08
colorectal cancer KRAS_G12A ARID1B 14 22 40-50yrs -1.57 -4.23 0.17 843.23 1.01 421 14 22 0 TRUE 0.81
colorectal cancer KRAS_G12A ARID1B 16 54 50-65yrs -1.47 -4.13 0.26 841.61 1.00 906 15 53 1 TRUE 0.76
colorectal cancer KRAS_G12A ARID1B 16 53 >65yrs -1.58 -4.16 0.07 914.55 1.00 584 16 53 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A ARID1B 25 43 50-65yrs 0.42 -0.82 1.75 1306.70 1.00 1251 23 41 2 TRUE 0.30
non-small cell lung cancer KRAS_G12A ARID1B 63 64 >65yrs 0.24 -1.05 1.26 982.90 1.00 2007 61 62 2 TRUE 0.17
colorectal cancer KRAS_G12A ARID1B 51 140 Age:overall -1.55 -4.16 0.12 844.10 1.00 2116 50 139 1 TRUE 0.82
non-small cell lung cancer KRAS_G12A ARID1B 88 107 Age:overall 0.33 -1.01 1.53 1134.63 1.00 3258 84 103 4 TRUE 0.21
non-small cell lung cancer KRAS_G12A INSR 25 23 50-65yrs -1.06 -4.57 1.09 1038.08 1.00 1264 25 23 0 FALSE 0.33
non-small cell lung cancer KRAS_G12A INSR 63 28 >65yrs -0.76 -3.62 1.09 897.82 1.00 2031 62 27 1 FALSE 0.27
non-small cell lung cancer KRAS_G12A INSR 88 51 Age:overall -0.88 -4.06 1.27 944.32 1.00 3295 87 50 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A NKX2-1 25 31 50-65yrs 1.06 -0.45 2.39 1286.74 1.00 1265 22 28 3 TRUE 0.90
non-small cell lung cancer KRAS_G12A NKX2-1 63 42 >65yrs 0.37 -1.36 1.52 331.93 1.02 2031 62 41 1 TRUE 0.20
non-small cell lung cancer KRAS_G12A NKX2-1 88 73 Age:overall 0.72 -1.14 2.14 1337.62 1.00 3296 84 69 4 TRUE 0.42
colorectal cancer KRAS_G12A ARID5B 14 20 40-50yrs -0.96 -4.11 1.05 1065.22 1.00 425 14 20 0 FALSE 0.32
colorectal cancer KRAS_G12A ARID5B 16 22 50-65yrs -0.96 -4.07 1.12 938.58 1.00 931 16 22 0 FALSE 0.32
colorectal cancer KRAS_G12A ARID5B 16 17 >65yrs -0.75 -3.72 1.25 1237.52 1.00 619 15 16 1 FALSE 0.26
colorectal cancer KRAS_G12A ARID5B 46 59 Age:overall -0.89 -3.86 1.12 1098.18 1.00 1975 45 58 1 FALSE 0.31
non-small cell lung cancer KRAS_G12A WT1 25 30 50-65yrs -0.77 -3.72 1.31 1025.96 1.00 1261 24 29 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A WT1 63 36 >65yrs -1.26 -4.68 0.64 1333.86 1.00 2033 63 36 0 TRUE 0.46
non-small cell lung cancer KRAS_G12A WT1 88 66 Age:overall -1.02 -4.03 1.06 1186.08 1.00 3294 87 65 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A MET 26 48 50-65yrs -0.57 -2.15 0.94 85.44 1.05 1307 25 47 1 TRUE 0.31
non-small cell lung cancer KRAS_G12A MET 65 111 >65yrs -0.66 -2.01 0.53 82.99 1.05 2018 63 109 2 TRUE 0.48
non-small cell lung cancer KRAS_G12A MET 91 159 Age:overall -0.58 -2.19 0.88 84.78 1.05 3325 88 156 3 TRUE 0.32
non-small cell lung cancer KRAS_G12A PMS1 25 17 50-65yrs -0.20 -3.07 1.63 1307.60 1.00 1273 25 17 0 TRUE 0.06
non-small cell lung cancer KRAS_G12A PMS1 63 35 >65yrs 0.16 -1.55 1.55 1042.73 1.00 2033 61 33 2 TRUE 0.08
non-small cell lung cancer KRAS_G12A PMS1 88 52 Age:overall -0.03 -2.35 1.75 1320.03 1.00 3306 86 50 2 TRUE 0.01
non-small cell lung cancer KRAS_G12A PIK3C3 25 29 50-65yrs 0.18 -2.63 1.57 358.55 1.01 1256 25 29 0 FALSE 0.05
non-small cell lung cancer KRAS_G12A PIK3C3 63 44 >65yrs 0.80 -0.50 1.82 612.77 1.01 2019 59 40 4 FALSE 0.78
non-small cell lung cancer KRAS_G12A PIK3C3 88 73 Age:overall 0.50 -1.67 1.81 420.06 1.01 3275 84 69 4 FALSE 0.24
colorectal cancer KRAS_G12A BRAF 15 34 40-50yrs -2.29 -5.08 -0.37 1236.66 1.00 437 15 34 0 TRUE 1.25
colorectal cancer KRAS_G12A BRAF 18 93 50-65yrs -2.15 -4.86 -0.26 1507.87 1.00 966 17 92 1 TRUE 1.16
colorectal cancer KRAS_G12A BRAF 18 105 >65yrs -2.31 -4.99 -0.43 1591.28 1.00 606 18 105 0 TRUE 1.31
non-small cell lung cancer KRAS_G12A BRAF 26 62 50-65yrs -2.35 -5.26 -0.12 140.57 1.04 1286 26 62 0 TRUE 1.02
non-small cell lung cancer KRAS_G12A BRAF 65 122 >65yrs -2.21 -4.64 -0.32 70.33 1.06 1999 64 121 1 TRUE 1.15
colorectal cancer KRAS_G12A BRAF 56 253 Age:overall -2.25 -4.95 -0.43 1531.42 1.00 2220 55 252 1 TRUE 1.27
non-small cell lung cancer KRAS_G12A BRAF 91 184 Age:overall -2.24 -4.80 -0.05 105.66 1.05 3285 90 183 1 TRUE 1.05
non-small cell lung cancer KRAS_G12A TGFBR1 25 16 50-65yrs 0.82 -0.95 2.17 1546.03 1.00 1269 24 15 1 FALSE 0.53
non-small cell lung cancer KRAS_G12A TGFBR1 63 31 >65yrs 0.76 -0.81 1.96 1346.13 1.00 2029 61 29 2 FALSE 0.58
non-small cell lung cancer KRAS_G12A TGFBR1 88 47 Age:overall 0.76 -1.08 2.15 1537.98 1.00 3298 85 44 3 FALSE 0.46
colorectal cancer KRAS_G12A TET2 14 19 40-50yrs -1.14 -3.85 0.68 920.78 1.00 423 13 18 1 TRUE 0.51
colorectal cancer KRAS_G12A TET2 16 29 50-65yrs -1.26 -4.01 0.57 891.34 1.00 925 16 29 0 TRUE 0.56
colorectal cancer KRAS_G12A TET2 16 27 >65yrs -1.26 -4.16 0.47 935.92 1.00 611 16 27 0 TRUE 0.57
non-small cell lung cancer KRAS_G12A TET2 25 33 50-65yrs -1.41 -4.68 0.69 1054.06 1.00 1260 25 33 0 TRUE 0.53
non-small cell lung cancer KRAS_G12A TET2 63 45 >65yrs -1.19 -4.02 0.76 1041.99 1.00 2023 62 44 1 TRUE 0.48
colorectal cancer KRAS_G12A TET2 51 91 Age:overall -1.23 -4.00 0.43 877.79 1.00 2160 50 90 1 TRUE 0.56
non-small cell lung cancer KRAS_G12A TET2 88 78 Age:overall -1.30 -4.31 0.81 1086.91 1.00 3283 87 77 1 TRUE 0.50
colorectal cancer KRAS_G12A PDGFRB 14 11 40-50yrs -0.84 -4.20 1.38 1195.99 1.00 425 14 11 0 TRUE 0.25
colorectal cancer KRAS_G12A PDGFRB 16 11 50-65yrs -0.31 -3.51 1.96 1326.05 1.00 941 15 10 1 TRUE 0.08
colorectal cancer KRAS_G12A PDGFRB 16 24 >65yrs -0.86 -4.08 1.32 1238.65 1.00 609 16 24 0 TRUE 0.27
non-small cell lung cancer KRAS_G12A PDGFRB 25 33 50-65yrs -0.70 -3.42 0.96 937.12 1.00 1260 25 33 0 TRUE 0.28
non-small cell lung cancer KRAS_G12A PDGFRB 63 55 >65yrs -0.36 -2.15 1.05 854.02 1.00 2018 61 53 2 TRUE 0.18
colorectal cancer KRAS_G12A PDGFRB 46 46 Age:overall -0.67 -3.68 1.49 1217.96 1.00 1975 45 45 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A PDGFRB 88 88 Age:overall -0.53 -2.85 1.12 1122.99 1.00 3278 86 86 2 TRUE 0.23
colorectal cancer KRAS_G12A CARD11 6 21 <40yrs 0.59 -0.72 1.73 1285.18 1.00 194 4 19 2 FALSE 0.46
colorectal cancer KRAS_G12A CARD11 14 20 40-50yrs 0.33 -1.23 1.48 1381.87 1.00 418 14 20 0 FALSE 0.21
colorectal cancer KRAS_G12A CARD11 16 45 50-65yrs 0.51 -0.72 1.54 1204.72 1.00 912 14 43 2 FALSE 0.41
colorectal cancer KRAS_G12A CARD11 16 42 >65yrs 0.39 -0.85 1.44 1316.20 1.00 597 15 41 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A CARD11 25 50 50-65yrs -0.44 -3.48 1.08 1160.90 1.00 1241 25 50 0 FALSE 0.13
non-small cell lung cancer KRAS_G12A CARD11 63 75 >65yrs 0.23 -0.94 1.25 1390.44 1.00 2000 59 71 4 FALSE 0.17
colorectal cancer KRAS_G12A CARD11 52 128 Age:overall 0.46 -0.72 1.48 1296.70 1.00 2121 47 123 5 FALSE 0.38
non-small cell lung cancer KRAS_G12A CARD11 88 125 Age:overall -0.10 -2.29 1.42 1348.13 1.00 3241 84 121 4 FALSE 0.04
colorectal cancer KRAS_G12A DNMT3A 14 11 40-50yrs -4.25 -11.08 -0.02 821.38 1.00 427 14 11 0 TRUE 0.81
colorectal cancer KRAS_G12A DNMT3A 16 21 50-65yrs -4.22 -11.16 0.04 793.79 1.00 931 16 21 0 TRUE 0.81
colorectal cancer KRAS_G12A DNMT3A 16 19 >65yrs -4.24 -11.08 -0.01 795.41 1.00 618 16 19 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A DNMT3A 25 30 50-65yrs -4.75 -11.73 -0.28 1027.36 1.00 1260 25 30 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A DNMT3A 63 42 >65yrs -4.75 -12.02 -0.23 1045.33 1.00 2024 63 42 0 TRUE 0.93
colorectal cancer KRAS_G12A DNMT3A 46 51 Age:overall -4.22 -11.07 0.00 799.27 1.00 1976 46 51 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A DNMT3A 88 72 Age:overall -4.68 -11.65 -0.23 1048.74 1.00 3284 88 72 0 TRUE 0.94
colorectal cancer KRAS_G12A MSH6 14 24 40-50yrs -0.42 -2.25 0.99 295.76 1.01 417 14 24 0 TRUE 0.20
colorectal cancer KRAS_G12A MSH6 16 38 50-65yrs -0.42 -2.31 0.96 255.49 1.02 923 16 38 0 TRUE 0.20
colorectal cancer KRAS_G12A MSH6 16 26 >65yrs -0.43 -2.32 1.00 303.46 1.01 610 16 26 0 TRUE 0.20
colorectal cancer KRAS_G12A MSH6 51 100 Age:overall -0.38 -2.25 0.98 247.12 1.01 2153 49 98 2 TRUE 0.18
non-small cell lung cancer KRAS_G12A MAX 25 15 50-65yrs 1.18 -0.39 2.38 1517.90 1.00 1270 24 14 1 FALSE 1.06
non-small cell lung cancer KRAS_G12A MAX 63 39 >65yrs 1.24 0.12 2.20 1478.13 1.00 2024 59 35 4 FALSE 1.75
non-small cell lung cancer KRAS_G12A MAX 88 54 Age:overall 1.20 -0.37 2.53 1675.46 1.00 3294 83 49 5 FALSE 0.97
non-small cell lung cancer KRAS_G12A INPP4B 25 46 50-65yrs 0.45 -0.79 1.48 1348.76 1.00 1249 23 44 2 FALSE 0.35
non-small cell lung cancer KRAS_G12A INPP4B 63 76 >65yrs 0.34 -0.83 1.25 1473.75 1.00 2000 60 73 3 FALSE 0.29
non-small cell lung cancer KRAS_G12A INPP4B 88 122 Age:overall 0.39 -0.97 1.53 1434.05 1.00 3249 83 117 5 FALSE 0.27
non-small cell lung cancer KRAS_G12A NFE2L2 25 39 50-65yrs -1.89 -5.28 0.34 1163.79 1.00 1253 25 39 0 FALSE 0.67
non-small cell lung cancer KRAS_G12A NFE2L2 63 85 >65yrs -1.63 -4.38 0.21 1378.13 1.00 1992 62 84 1 FALSE 0.78
non-small cell lung cancer KRAS_G12A NFE2L2 88 124 Age:overall -1.72 -4.60 0.32 1340.28 1.00 3245 87 123 1 FALSE 0.73
colorectal cancer KRAS_G12A SOX9 6 22 <40yrs 0.78 -0.05 1.65 1262.47 1.00 194 3 19 3 FALSE 1.12
colorectal cancer KRAS_G12A SOX9 15 41 40-50yrs 0.64 -0.19 1.42 966.72 1.00 397 13 39 2 FALSE 0.90
colorectal cancer KRAS_G12A SOX9 17 114 50-65yrs 0.67 -0.09 1.43 1143.66 1.00 856 13 110 4 FALSE 1.05
colorectal cancer KRAS_G12A SOX9 16 87 >65yrs 0.59 -0.25 1.33 1028.82 1.00 554 14 85 2 FALSE 0.81
colorectal cancer KRAS_G12A SOX9 54 264 Age:overall 0.67 -0.06 1.37 1172.78 1.00 2001 43 253 11 FALSE 1.10
colorectal cancer KRAS_G12A ARAF 16 22 50-65yrs -4.53 -12.06 0.44 255.88 1.02 932 16 22 0 FALSE 0.75
colorectal cancer KRAS_G12A ARAF 16 23 >65yrs -4.50 -11.99 0.24 247.38 1.02 612 16 23 0 FALSE 0.77
non-small cell lung cancer KRAS_G12A ARAF 25 26 50-65yrs -0.02 -1.91 1.50 970.62 1.00 1269 24 25 1 FALSE 0.01
non-small cell lung cancer KRAS_G12A ARAF 63 42 >65yrs -0.18 -2.02 1.19 1128.48 1.00 2029 62 41 1 FALSE 0.08
colorectal cancer KRAS_G12A ARAF 32 45 Age:overall -4.43 -11.84 0.31 224.38 1.02 1544 32 45 0 FALSE 0.76
non-small cell lung cancer KRAS_G12A ARAF 88 68 Age:overall -0.10 -2.04 1.49 1106.51 1.00 3298 86 66 2 FALSE 0.04
non-small cell lung cancer KRAS_G12A JAK2 27 38 50-65yrs 0.15 -1.96 1.79 1297.70 1.00 1313 25 36 2 TRUE 0.06
non-small cell lung cancer KRAS_G12A JAK2 65 35 >65yrs -0.93 -4.08 0.95 1248.98 1.00 2083 65 35 0 TRUE 0.29
non-small cell lung cancer KRAS_G12A JAK2 92 73 Age:overall -0.35 -3.06 1.75 1381.90 1.00 3396 90 71 2 TRUE 0.11
colorectal cancer KRAS_G12A SMAD2 14 33 40-50yrs -0.32 -2.20 1.14 1320.04 1.00 411 13 32 1 TRUE 0.15
colorectal cancer KRAS_G12A SMAD2 16 39 50-65yrs -0.25 -2.15 1.28 1176.28 1.00 917 15 38 1 TRUE 0.11
colorectal cancer KRAS_G12A SMAD2 16 20 >65yrs -0.47 -2.56 1.14 1169.76 1.00 613 16 20 0 TRUE 0.19
colorectal cancer KRAS_G12A SMAD2 46 92 Age:overall -0.35 -2.23 1.12 1213.68 1.00 1941 44 90 2 TRUE 0.16
non-small cell lung cancer KRAS_G12A TP63 25 31 50-65yrs -0.98 -4.18 1.27 217.65 1.01 1255 24 30 1 FALSE 0.32
non-small cell lung cancer KRAS_G12A TP63 63 38 >65yrs -1.46 -4.93 0.75 698.52 1.00 2021 63 38 0 FALSE 0.49
non-small cell lung cancer KRAS_G12A TP63 88 69 Age:overall -1.19 -4.42 1.21 335.47 1.00 3276 87 68 1 FALSE 0.39
non-small cell lung cancer KRAS_G12A MYOD1 25 21 50-65yrs -4.66 -12.14 0.27 527.90 1.00 1267 25 21 0 FALSE 0.90
non-small cell lung cancer KRAS_G12A MYOD1 63 31 >65yrs -4.70 -12.13 0.10 506.28 1.00 2027 63 31 0 FALSE 0.94
non-small cell lung cancer KRAS_G12A MYOD1 88 52 Age:overall -4.62 -11.99 0.19 500.80 1.00 3294 88 52 0 FALSE 0.93
colorectal cancer KRAS_G12A FGFR1 15 12 40-50yrs -4.59 -11.28 0.13 179.76 1.02 458 15 12 0 TRUE 0.89
colorectal cancer KRAS_G12A FGFR1 18 21 50-65yrs -4.57 -11.17 0.16 173.23 1.02 1038 18 21 0 TRUE 0.88
colorectal cancer KRAS_G12A FGFR1 18 11 >65yrs -4.59 -11.16 0.12 181.15 1.02 693 18 11 0 TRUE 0.89
colorectal cancer KRAS_G12A FGFR1 51 44 Age:overall -4.58 -11.14 0.13 173.75 1.02 2189 51 44 0 TRUE 0.89
colorectal cancer KRAS_G12A MITF 16 25 50-65yrs -4.22 -11.18 0.34 95.78 1.03 927 16 25 0 FALSE 0.78
colorectal cancer KRAS_G12A MITF 16 14 >65yrs -4.20 -11.11 0.44 97.82 1.03 619 16 14 0 FALSE 0.76
colorectal cancer KRAS_G12A MITF 32 39 Age:overall -4.16 -10.89 0.41 97.92 1.03 1546 32 39 0 FALSE 0.77
non-small cell lung cancer KRAS_G12A BTK 25 28 50-65yrs -4.38 -11.55 0.06 920.73 1.00 1262 25 28 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A BTK 63 29 >65yrs -4.42 -11.51 -0.16 1002.31 1.00 2037 63 29 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A BTK 88 57 Age:overall -4.30 -11.29 0.08 957.16 1.00 3299 88 57 0 TRUE 0.84
non-small cell lung cancer KRAS_G12A GLI1 23 35 50-65yrs -1.31 -4.26 0.87 686.57 1.00 1105 22 34 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A GLI1 60 64 >65yrs -1.73 -4.91 0.26 902.51 1.00 1843 60 64 0 FALSE 0.68
non-small cell lung cancer KRAS_G12A GLI1 83 99 Age:overall -1.52 -4.60 0.60 789.91 1.00 2948 82 98 1 FALSE 0.62
non-small cell lung cancer KRAS_G12A ZFHX3 23 57 50-65yrs 0.18 -1.02 1.27 666.71 1.01 1084 21 55 2 FALSE 0.12
non-small cell lung cancer KRAS_G12A ZFHX3 60 96 >65yrs 0.09 -1.02 0.94 467.45 1.00 1813 57 93 3 FALSE 0.07
non-small cell lung cancer KRAS_G12A ZFHX3 83 153 Age:overall 0.14 -1.17 1.36 857.82 1.00 2897 78 148 5 FALSE 0.08
non-small cell lung cancer KRAS_G12A MGA 23 60 50-65yrs -0.01 -1.21 1.19 1045.50 1.00 1082 21 58 2 FALSE 0.00
non-small cell lung cancer KRAS_G12A MGA 60 129 >65yrs -0.21 -1.40 0.77 907.12 1.00 1795 57 126 3 FALSE 0.15
non-small cell lung cancer KRAS_G12A MGA 83 189 Age:overall -0.13 -1.55 1.10 1121.18 1.00 2877 78 184 5 FALSE 0.07
non-small cell lung cancer KRAS_G12A ANKRD11 23 21 50-65yrs -0.52 -3.31 1.20 1145.89 1.00 1110 23 21 0 FALSE 0.19
non-small cell lung cancer KRAS_G12A ANKRD11 60 50 >65yrs -0.22 -2.11 1.14 1076.52 1.00 1851 58 48 2 FALSE 0.10
non-small cell lung cancer KRAS_G12A ANKRD11 83 71 Age:overall -0.35 -2.68 1.25 1204.85 1.00 2961 81 69 2 FALSE 0.14
non-small cell lung cancer KRAS_G12A PGR 23 35 50-65yrs -1.29 -4.68 0.58 200.74 1.02 1098 23 35 0 FALSE 0.34
non-small cell lung cancer KRAS_G12A PGR 60 49 >65yrs -1.11 -3.96 0.55 119.50 1.02 1848 59 48 1 FALSE 0.46
non-small cell lung cancer KRAS_G12A PGR 83 84 Age:overall -1.17 -4.19 0.63 130.45 1.02 2946 82 83 1 FALSE 0.46
non-small cell lung cancer KRAS_G12A PLCG2 23 13 50-65yrs -1.25 -5.04 1.21 1305.94 1.00 1119 23 13 0 FALSE 0.35
non-small cell lung cancer KRAS_G12A PLCG2 60 43 >65yrs -0.97 -3.87 0.97 1212.75 1.00 1858 59 42 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A PLCG2 83 56 Age:overall -1.07 -4.31 1.13 1208.59 1.00 2977 82 55 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A POLD1 23 23 50-65yrs -4.69 -12.61 0.14 559.06 1.00 1114 23 23 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A POLD1 60 32 >65yrs -4.76 -12.16 -0.05 547.49 1.00 1870 60 32 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A POLD1 83 55 Age:overall -4.65 -12.15 0.01 549.17 1.00 2984 83 55 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A INHBA 23 29 50-65yrs -1.50 -5.05 0.59 1165.10 1.00 1108 23 29 0 FALSE 0.55
non-small cell lung cancer KRAS_G12A INHBA 60 55 >65yrs -1.29 -3.96 0.55 1200.63 1.00 1854 59 54 1 FALSE 0.58
non-small cell lung cancer KRAS_G12A INHBA 83 84 Age:overall -1.36 -4.17 0.66 1352.41 1.00 2962 82 83 1 FALSE 0.55
colorectal cancer KRAS_G12A AMER1 14 33 40-50yrs -1.93 -4.95 -0.03 730.72 1.00 405 14 33 0 FALSE 0.90
colorectal cancer KRAS_G12A AMER1 16 53 50-65yrs -1.94 -4.84 0.02 815.13 1.00 901 16 53 0 FALSE 0.92
colorectal cancer KRAS_G12A AMER1 16 70 >65yrs -1.81 -4.61 0.04 662.53 1.00 570 15 69 1 FALSE 0.85
non-small cell lung cancer KRAS_G12A AMER1 25 48 50-65yrs 0.33 -0.90 1.51 1430.24 1.00 1248 23 46 2 FALSE 0.23
non-small cell lung cancer KRAS_G12A AMER1 63 93 >65yrs 0.17 -0.94 1.13 1382.78 1.00 1990 60 90 3 FALSE 0.13
colorectal cancer KRAS_G12A AMER1 51 169 Age:overall -1.89 -4.78 -0.06 712.70 1.00 2078 50 168 1 FALSE 0.92
non-small cell lung cancer KRAS_G12A AMER1 88 141 Age:overall 0.27 -1.02 1.46 1484.88 1.00 3238 83 136 5 FALSE 0.17
non-small cell lung cancer KRAS_G12A EPHA7 23 48 50-65yrs -0.66 -2.62 0.82 1037.41 1.00 1094 22 47 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A EPHA7 60 77 >65yrs -0.82 -2.75 0.54 988.00 1.00 1828 59 76 1 FALSE 0.49
non-small cell lung cancer KRAS_G12A EPHA7 83 125 Age:overall -0.73 -2.74 0.89 1176.66 1.00 2922 81 123 2 FALSE 0.37
colorectal cancer KRAS_G12C SPEN 6 23 <40yrs -5.36 -12.07 -1.18 1186.54 1.00 197 6 23 0 FALSE 1.20
colorectal cancer KRAS_G12C SPEN 10 25 40-50yrs -5.38 -12.28 -1.36 1168.76 1.00 420 10 25 0 FALSE 1.19
colorectal cancer KRAS_G12C SPEN 31 45 50-65yrs -5.37 -12.30 -1.31 1204.96 1.00 901 31 45 0 FALSE 1.21
colorectal cancer KRAS_G12C SPEN 23 62 >65yrs -5.38 -12.42 -1.37 1161.84 1.00 582 23 62 0 FALSE 1.21
non-small cell lung cancer KRAS_G12C SPEN 152 67 50-65yrs -1.10 -2.20 -0.17 1405.03 1.00 1123 149 64 3 FALSE 1.50
non-small cell lung cancer KRAS_G12C SPEN 292 49 >65yrs -1.08 -2.25 -0.11 1504.02 1.00 1798 289 46 3 FALSE 1.38
colorectal cancer KRAS_G12C SPEN 70 155 Age:overall -5.37 -12.25 -1.36 1191.47 1.00 2100 70 155 0 FALSE 1.21
non-small cell lung cancer KRAS_G12C SPEN 444 116 Age:overall -1.08 -2.44 0.15 1472.14 1.00 2921 438 110 6 FALSE 0.99
colorectal cancer KRAS_G12C KMT2C 10 39 40-50yrs -5.62 -12.82 -1.27 110.87 1.02 402 10 39 0 FALSE 1.26
colorectal cancer KRAS_G12C KMT2C 29 65 50-65yrs -5.61 -12.89 -1.31 110.38 1.02 860 29 65 0 FALSE 1.25
colorectal cancer KRAS_G12C KMT2C 22 69 >65yrs -5.62 -12.85 -1.23 111.54 1.02 559 22 69 0 FALSE 1.25
non-small cell lung cancer KRAS_G12C KMT2C 153 90 50-65yrs -0.01 -0.56 0.44 1370.50 1.00 1087 143 80 10 FALSE 0.02
non-small cell lung cancer KRAS_G12C KMT2C 291 122 >65yrs 0.04 -0.42 0.46 1252.14 1.00 1732 273 104 18 FALSE 0.06
colorectal cancer KRAS_G12C KMT2C 66 198 Age:overall -5.61 -12.85 -1.32 109.95 1.02 2011 66 198 0 FALSE 1.26
non-small cell lung cancer KRAS_G12C KMT2C 444 212 Age:overall 0.02 -0.61 0.63 1470.64 1.00 2819 416 184 28 FALSE 0.02
colorectal cancer KRAS_G12C TP53 8 165 <40yrs -0.36 -0.88 0.18 1255.48 1.00 80 2 159 6 TRUE 0.72
colorectal cancer KRAS_G12C TP53 10 350 40-50yrs -0.44 -1.02 0.08 1179.84 1.00 148 4 344 6 TRUE 0.97
colorectal cancer KRAS_G12C TP53 41 724 50-65yrs -0.38 -0.83 0.07 1263.51 1.00 379 18 701 23 TRUE 0.92
colorectal cancer KRAS_G12C TP53 25 480 >65yrs -0.42 -0.92 0.05 1117.38 1.00 276 13 468 12 TRUE 1.01
non-small cell lung cancer KRAS_G12C TP53 11 102 40-50yrs 0.10 -0.86 1.37 1455.19 1.00 100 3 94 8 TRUE 0.07
non-small cell lung cancer KRAS_G12C TP53 163 814 50-65yrs -0.73 -1.08 -0.40 1509.31 1.00 521 98 749 65 TRUE 4.90
non-small cell lung cancer KRAS_G12C TP53 307 1113 >65yrs -0.68 -0.92 -0.44 1332.41 1.00 950 201 1007 106 TRUE 7.23
colorectal cancer KRAS_G12C TP53 84 1719 Age:overall -0.40 -0.88 0.06 1258.98 1.00 883 37 1672 47 TRUE 0.99
non-small cell lung cancer KRAS_G12C TP53 482 2056 Age:overall -0.41 -1.19 0.62 1410.17 1.00 1609 302 1876 180 TRUE 0.44
colorectal cancer KRAS_G12C ATRX 10 31 40-50yrs -1.59 -4.21 0.46 1419.02 1.00 418 9 30 1 TRUE 0.71
colorectal cancer KRAS_G12C ATRX 31 31 50-65yrs -1.93 -4.81 0.03 1535.35 1.00 907 31 31 0 TRUE 0.90
colorectal cancer KRAS_G12C ATRX 23 48 >65yrs -1.97 -4.71 -0.11 1465.74 1.00 587 23 48 0 TRUE 0.98
non-small cell lung cancer KRAS_G12C ATRX 154 74 50-65yrs 0.66 0.20 1.12 1194.76 1.00 1113 138 58 16 TRUE 2.31
non-small cell lung cancer KRAS_G12C ATRX 294 123 >65yrs 0.58 0.16 0.94 1282.96 1.00 1754 269 98 25 TRUE 2.38
colorectal cancer KRAS_G12C ATRX 64 110 Age:overall -1.81 -4.40 0.06 1501.69 1.00 1912 63 109 1 TRUE 0.90
non-small cell lung cancer KRAS_G12C ATRX 448 197 Age:overall 0.63 0.11 1.17 1504.83 1.00 2867 407 156 41 TRUE 1.57
colorectal cancer KRAS_G12C ATR 6 17 <40yrs -4.71 -10.90 -0.85 259.07 1.01 199 6 17 0 FALSE 1.09
colorectal cancer KRAS_G12C ATR 10 22 40-50yrs -4.71 -10.85 -0.91 263.67 1.01 428 10 22 0 FALSE 1.09
colorectal cancer KRAS_G12C ATR 31 48 50-65yrs -4.70 -10.79 -0.88 258.07 1.01 901 31 48 0 FALSE 1.09
colorectal cancer KRAS_G12C ATR 23 27 >65yrs -4.70 -10.87 -0.89 261.64 1.01 602 23 27 0 FALSE 1.10
non-small cell lung cancer KRAS_G12C ATR 152 50 50-65yrs 0.05 -0.60 0.60 1333.94 1.00 1122 146 44 6 FALSE 0.05
non-small cell lung cancer KRAS_G12C ATR 291 73 >65yrs 0.07 -0.47 0.62 1423.23 1.00 1776 280 62 11 FALSE 0.10
colorectal cancer KRAS_G12C ATR 70 114 Age:overall -4.70 -10.85 -0.91 259.25 1.01 2130 70 114 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C ATR 443 123 Age:overall 0.06 -0.63 0.69 1398.14 1.00 2898 426 106 17 FALSE 0.06
colorectal cancer KRAS_G12C PDGFRA 7 12 <40yrs 0.21 -1.45 1.50 1235.82 1.00 220 7 12 0 TRUE 0.11
colorectal cancer KRAS_G12C PDGFRA 10 14 40-50yrs 0.20 -1.47 1.48 1224.68 1.00 460 10 14 0 TRUE 0.11
colorectal cancer KRAS_G12C PDGFRA 39 22 50-65yrs 0.36 -1.11 1.54 1189.87 1.00 1017 37 20 2 TRUE 0.23
colorectal cancer KRAS_G12C PDGFRA 25 12 >65yrs 0.30 -1.29 1.56 1244.30 1.00 685 24 11 1 TRUE 0.17
non-small cell lung cancer KRAS_G12C PDGFRA 160 57 50-65yrs 0.50 -0.03 1.05 1459.00 1.00 1171 149 46 11 TRUE 1.18
non-small cell lung cancer KRAS_G12C PDGFRA 301 86 >65yrs 0.43 -0.06 0.88 1464.56 1.00 1817 285 70 16 TRUE 1.14
colorectal cancer KRAS_G12C PDGFRA 81 60 Age:overall 0.28 -1.26 1.43 1250.32 1.00 2382 78 57 3 TRUE 0.17
non-small cell lung cancer KRAS_G12C PDGFRA 461 143 Age:overall 0.46 -0.15 1.10 1409.63 1.00 2988 434 116 27 TRUE 0.79
colorectal cancer KRAS_G12C FBXW7 7 28 <40yrs -0.16 -0.97 0.58 813.44 1.01 203 7 28 0 TRUE 0.16
colorectal cancer KRAS_G12C FBXW7 10 60 40-50yrs -0.13 -0.94 0.57 839.14 1.01 424 8 58 2 TRUE 0.13
colorectal cancer KRAS_G12C FBXW7 40 144 50-65yrs -0.15 -0.90 0.54 643.06 1.01 912 36 140 4 TRUE 0.17
colorectal cancer KRAS_G12C FBXW7 26 107 >65yrs -0.12 -0.89 0.56 741.49 1.00 608 22 103 4 TRUE 0.13
non-small cell lung cancer KRAS_G12C FBXW7 160 32 50-65yrs -0.49 -1.50 0.36 1050.77 1.00 1185 158 30 2 TRUE 0.51
non-small cell lung cancer KRAS_G12C FBXW7 302 51 >65yrs -0.37 -1.17 0.38 1375.97 1.00 1841 296 45 6 TRUE 0.46
colorectal cancer KRAS_G12C FBXW7 83 339 Age:overall -0.14 -0.90 0.56 701.26 1.00 2147 73 329 10 TRUE 0.16
non-small cell lung cancer KRAS_G12C FBXW7 462 83 Age:overall -0.43 -1.42 0.50 1377.98 1.00 3026 454 75 8 TRUE 0.40
colorectal cancer KRAS_G12C MAP3K1 10 24 40-50yrs -0.57 -2.55 0.79 455.83 1.00 421 10 24 0 FALSE 0.30
colorectal cancer KRAS_G12C MAP3K1 31 34 50-65yrs -0.40 -2.17 0.94 641.54 1.00 906 29 32 2 FALSE 0.21
colorectal cancer KRAS_G12C MAP3K1 23 25 >65yrs -0.59 -2.53 0.75 611.72 1.00 605 23 25 0 FALSE 0.30
non-small cell lung cancer KRAS_G12C MAP3K1 152 28 50-65yrs 0.92 0.18 1.65 1372.57 1.00 1144 144 20 8 FALSE 1.89
non-small cell lung cancer KRAS_G12C MAP3K1 291 33 >65yrs 0.70 -0.02 1.39 1341.31 1.00 1812 284 26 7 FALSE 1.31
colorectal cancer KRAS_G12C MAP3K1 64 83 Age:overall -0.52 -2.40 0.79 606.00 1.00 1932 62 81 2 FALSE 0.28
non-small cell lung cancer KRAS_G12C MAP3K1 443 61 Age:overall 0.81 -0.06 1.69 1200.87 1.00 2956 428 46 15 FALSE 0.99
colorectal cancer KRAS_G12C NSD1 6 15 <40yrs -1.54 -4.54 0.46 1450.14 1.00 198 6 15 0 FALSE 0.66
colorectal cancer KRAS_G12C NSD1 10 16 40-50yrs -1.52 -4.42 0.49 1435.68 1.00 428 10 16 0 FALSE 0.66
colorectal cancer KRAS_G12C NSD1 31 22 50-65yrs -1.55 -4.51 0.52 1515.47 1.00 915 31 22 0 FALSE 0.67
colorectal cancer KRAS_G12C NSD1 23 33 >65yrs -1.39 -4.24 0.51 1488.34 1.00 601 22 32 1 FALSE 0.62
non-small cell lung cancer KRAS_G12C NSD1 152 31 50-65yrs -0.29 -1.33 0.48 1101.43 1.00 1134 150 29 2 FALSE 0.27
non-small cell lung cancer KRAS_G12C NSD1 291 55 >65yrs -0.11 -0.90 0.55 1026.57 1.00 1791 283 47 8 FALSE 0.12
colorectal cancer KRAS_G12C NSD1 70 86 Age:overall -1.49 -4.45 0.40 1421.62 1.00 2142 69 85 1 FALSE 0.68
non-small cell lung cancer KRAS_G12C NSD1 443 86 Age:overall -0.20 -1.34 0.70 1327.31 1.00 2925 433 76 10 FALSE 0.16
colorectal cancer KRAS_G12C FLT4 10 24 40-50yrs -2.02 -4.94 0.00 1437.75 1.00 420 10 24 0 TRUE 0.93
colorectal cancer KRAS_G12C FLT4 31 42 50-65yrs -2.04 -5.01 -0.05 1409.22 1.00 896 31 42 0 TRUE 1.01
colorectal cancer KRAS_G12C FLT4 23 63 >65yrs -1.83 -4.50 -0.04 1458.00 1.00 575 22 62 1 TRUE 0.95
non-small cell lung cancer KRAS_G12C FLT4 153 43 50-65yrs 0.57 -0.13 1.27 1210.80 1.00 1130 143 33 10 TRUE 0.97
non-small cell lung cancer KRAS_G12C FLT4 291 54 >65yrs 0.18 -0.58 0.79 1116.66 1.00 1793 284 47 7 TRUE 0.21
colorectal cancer KRAS_G12C FLT4 64 129 Age:overall -1.96 -4.69 -0.09 1377.72 1.00 1891 63 128 1 TRUE 1.00
non-small cell lung cancer KRAS_G12C FLT4 444 97 Age:overall 0.38 -0.55 1.36 1144.98 1.00 2923 427 80 17 TRUE 0.37
colorectal cancer KRAS_G12C PTPRD 10 18 40-50yrs -1.16 -3.84 0.41 5.66 1.22 428 10 18 0 FALSE 0.44
colorectal cancer KRAS_G12C PTPRD 31 43 50-65yrs -1.13 -3.82 0.41 5.80 1.22 901 30 42 1 FALSE 0.44
colorectal cancer KRAS_G12C PTPRD 23 32 >65yrs -1.17 -3.87 0.40 5.48 1.23 599 23 32 0 FALSE 0.44
non-small cell lung cancer KRAS_G12C PTPRD 11 13 40-50yrs 0.16 -0.81 1.09 1663.50 1.00 171 10 12 1 FALSE 0.13
non-small cell lung cancer KRAS_G12C PTPRD 157 163 50-65yrs 0.30 -0.12 0.72 1352.28 1.00 1047 132 138 25 FALSE 0.84
non-small cell lung cancer KRAS_G12C PTPRD 296 214 >65yrs 0.11 -0.29 0.47 1187.23 1.00 1679 265 183 31 FALSE 0.24
colorectal cancer KRAS_G12C PTPRD 64 93 Age:overall -1.15 -3.89 0.40 5.47 1.22 1928 63 92 1 FALSE 0.45
non-small cell lung cancer KRAS_G12C PTPRD 464 390 Age:overall 0.20 -0.48 0.86 1435.26 1.00 2897 407 333 57 FALSE 0.26
colorectal cancer KRAS_G12C RET 39 30 50-65yrs 0.41 -1.13 1.58 906.53 1.00 1007 37 28 2 TRUE 0.26
colorectal cancer KRAS_G12C RET 25 20 >65yrs 0.36 -1.20 1.63 945.81 1.00 678 24 19 1 TRUE 0.21
non-small cell lung cancer KRAS_G12C RET 159 29 50-65yrs 0.56 -0.14 1.22 845.58 1.00 1192 153 23 6 TRUE 0.99
non-small cell lung cancer KRAS_G12C RET 300 61 >65yrs 0.57 -0.01 1.12 1271.90 1.00 1837 287 48 13 TRUE 1.33
colorectal cancer KRAS_G12C RET 64 50 Age:overall 0.37 -1.34 1.65 820.93 1.00 1685 61 47 3 TRUE 0.21
non-small cell lung cancer KRAS_G12C RET 459 90 Age:overall 0.57 -0.17 1.33 1271.77 1.00 3029 440 71 19 TRUE 0.82
colorectal cancer KRAS_G12C KDM5A 10 21 40-50yrs -4.67 -10.76 -0.73 35.04 1.14 427 10 21 0 FALSE 1.04
colorectal cancer KRAS_G12C KDM5A 31 35 50-65yrs -4.69 -10.68 -0.71 34.38 1.14 909 31 35 0 FALSE 1.05
colorectal cancer KRAS_G12C KDM5A 23 30 >65yrs -4.69 -10.70 -0.68 34.89 1.14 598 23 30 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C KDM5A 152 25 50-65yrs 0.39 -0.40 1.12 1389.49 1.00 1143 148 21 4 FALSE 0.52
non-small cell lung cancer KRAS_G12C KDM5A 292 45 >65yrs 0.41 -0.28 1.02 1434.26 1.00 1803 283 36 9 FALSE 0.67
colorectal cancer KRAS_G12C KDM5A 64 86 Age:overall -4.68 -10.70 -0.72 34.58 1.14 1934 64 86 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C KDM5A 444 70 Age:overall 0.39 -0.45 1.12 1448.57 1.00 2946 431 57 13 FALSE 0.44
colorectal cancer KRAS_G12C PIK3C2G 10 21 40-50yrs -1.45 -4.21 0.57 250.26 1.01 408 10 21 0 FALSE 0.62
colorectal cancer KRAS_G12C PIK3C2G 29 32 50-65yrs -1.46 -4.18 0.49 246.92 1.01 885 29 32 0 FALSE 0.64
colorectal cancer KRAS_G12C PIK3C2G 22 28 >65yrs -1.39 -4.04 0.53 240.96 1.01 587 21 27 1 FALSE 0.61
non-small cell lung cancer KRAS_G12C PIK3C2G 153 51 50-65yrs -0.20 -0.97 0.50 1298.38 1.00 1115 146 44 7 FALSE 0.22
non-small cell lung cancer KRAS_G12C PIK3C2G 291 73 >65yrs -0.49 -1.31 0.17 672.02 1.00 1767 286 68 5 FALSE 0.66
colorectal cancer KRAS_G12C PIK3C2G 61 81 Age:overall -1.43 -4.12 0.49 241.51 1.01 1880 60 80 1 FALSE 0.64
non-small cell lung cancer KRAS_G12C PIK3C2G 444 124 Age:overall -0.35 -1.25 0.45 943.95 1.00 2882 432 112 12 FALSE 0.37
non-small cell lung cancer KRAS_G12C TSHR 152 23 50-65yrs 0.49 -0.30 1.18 1113.59 1.00 1144 148 19 4 TRUE 0.68
non-small cell lung cancer KRAS_G12C TSHR 292 42 >65yrs 0.52 -0.18 1.15 1245.05 1.00 1806 283 33 9 TRUE 0.89
non-small cell lung cancer KRAS_G12C TSHR 444 65 Age:overall 0.50 -0.29 1.26 1239.57 1.00 2950 431 52 13 TRUE 0.63
colorectal cancer KRAS_G12C CREBBP 6 18 <40yrs -0.92 -2.52 0.43 1606.93 1.00 197 6 18 0 TRUE 0.64
colorectal cancer KRAS_G12C CREBBP 10 31 40-50yrs -0.82 -2.40 0.53 1568.00 1.00 419 9 30 1 TRUE 0.57
colorectal cancer KRAS_G12C CREBBP 31 58 50-65yrs -0.88 -2.45 0.32 1525.86 1.00 893 30 57 1 TRUE 0.67
colorectal cancer KRAS_G12C CREBBP 23 81 >65yrs -0.92 -2.45 0.26 1517.19 1.00 565 22 80 1 TRUE 0.73
non-small cell lung cancer KRAS_G12C CREBBP 152 48 50-65yrs -0.30 -1.00 0.38 1406.88 1.00 1122 148 44 4 TRUE 0.40
non-small cell lung cancer KRAS_G12C CREBBP 291 83 >65yrs -0.22 -0.84 0.33 1205.78 1.00 1769 281 73 10 TRUE 0.34
colorectal cancer KRAS_G12C CREBBP 70 188 Age:overall -0.88 -2.38 0.26 1549.65 1.00 2074 67 185 3 TRUE 0.72
non-small cell lung cancer KRAS_G12C CREBBP 443 131 Age:overall -0.26 -0.99 0.42 1117.19 1.00 2891 429 117 14 TRUE 0.31
non-small cell lung cancer KRAS_G12C BRIP1 152 30 50-65yrs 0.00 -0.94 0.80 1191.31 1.00 1137 149 27 3 TRUE 0.00
non-small cell lung cancer KRAS_G12C BRIP1 291 40 >65yrs 0.10 -0.67 0.80 916.75 1.00 1804 284 33 7 TRUE 0.10
non-small cell lung cancer KRAS_G12C BRIP1 443 70 Age:overall 0.04 -0.93 0.93 997.50 1.00 2941 433 60 10 TRUE 0.03
colorectal cancer KRAS_G12C AXIN2 10 25 40-50yrs -5.31 -11.32 -1.14 49.83 1.04 421 10 25 0 TRUE 1.51
colorectal cancer KRAS_G12C AXIN2 31 45 50-65yrs -5.32 -11.44 -1.13 55.36 1.04 898 31 45 0 TRUE 1.51
colorectal cancer KRAS_G12C AXIN2 23 39 >65yrs -5.33 -11.16 -1.21 48.57 1.04 592 23 39 0 TRUE 1.53
non-small cell lung cancer KRAS_G12C AXIN2 152 28 50-65yrs 0.09 -0.85 0.96 1417.34 1.00 1138 149 25 3 TRUE 0.07
non-small cell lung cancer KRAS_G12C AXIN2 291 30 >65yrs 0.25 -0.64 1.05 1457.07 1.00 1813 285 24 6 TRUE 0.25
colorectal cancer KRAS_G12C AXIN2 64 109 Age:overall -5.32 -11.31 -1.16 49.58 1.04 1911 64 109 0 TRUE 1.52
non-small cell lung cancer KRAS_G12C AXIN2 443 58 Age:overall 0.16 -0.91 1.20 1465.05 1.00 2951 434 49 9 TRUE 0.12
colorectal cancer KRAS_G12C DOT1L 6 19 <40yrs -1.58 -4.60 0.51 1202.17 1.00 196 6 19 0 FALSE 0.67
colorectal cancer KRAS_G12C DOT1L 10 12 40-50yrs -1.58 -4.54 0.61 1277.07 1.00 429 10 12 0 FALSE 0.66
colorectal cancer KRAS_G12C DOT1L 31 21 50-65yrs -1.61 -4.59 0.40 1196.09 1.00 919 31 21 0 FALSE 0.71
colorectal cancer KRAS_G12C DOT1L 23 32 >65yrs -1.37 -4.18 0.64 1177.58 1.00 599 22 31 1 FALSE 0.60
non-small cell lung cancer KRAS_G12C DOT1L 153 35 50-65yrs 0.13 -0.60 0.85 1162.40 1.00 1134 147 29 6 FALSE 0.14
non-small cell lung cancer KRAS_G12C DOT1L 291 66 >65yrs -0.01 -0.68 0.58 1170.32 1.00 1781 283 58 8 FALSE 0.01
colorectal cancer KRAS_G12C DOT1L 70 84 Age:overall -1.53 -4.45 0.38 1169.19 1.00 2143 69 83 1 FALSE 0.72
non-small cell lung cancer KRAS_G12C DOT1L 444 101 Age:overall 0.06 -0.69 0.80 1306.19 1.00 2915 430 87 14 FALSE 0.05
colorectal cancer KRAS_G12C PTPRS 10 51 40-50yrs -0.97 -2.46 -0.01 10.56 1.14 386 10 51 0 FALSE 0.77
colorectal cancer KRAS_G12C PTPRS 29 98 50-65yrs -0.96 -2.51 -0.01 11.73 1.13 833 28 97 1 FALSE 0.77
colorectal cancer KRAS_G12C PTPRS 22 79 >65yrs -0.95 -2.46 0.01 10.84 1.14 545 21 78 1 FALSE 0.77
non-small cell lung cancer KRAS_G12C PTPRS 152 31 50-65yrs 0.41 -0.39 1.08 834.27 1.00 1130 148 27 4 FALSE 0.57
non-small cell lung cancer KRAS_G12C PTPRS 295 46 >65yrs 0.58 -0.03 1.19 407.42 1.01 1798 283 34 12 FALSE 1.23
colorectal cancer KRAS_G12C PTPRS 66 254 Age:overall -0.96 -2.43 -0.02 10.97 1.14 1951 63 251 3 FALSE 0.78
non-small cell lung cancer KRAS_G12C PTPRS 447 77 Age:overall 0.49 -0.36 1.28 1108.87 1.00 2928 431 61 16 FALSE 0.59
colorectal cancer KRAS_G12C SMARCA4 6 19 <40yrs -2.34 -4.91 -0.45 223.67 1.01 197 6 19 0 FALSE 1.30
colorectal cancer KRAS_G12C SMARCA4 10 24 40-50yrs -2.34 -4.98 -0.42 263.74 1.01 420 10 24 0 FALSE 1.29
colorectal cancer KRAS_G12C SMARCA4 31 65 50-65yrs -2.36 -4.91 -0.48 243.84 1.01 887 31 65 0 FALSE 1.34
colorectal cancer KRAS_G12C SMARCA4 23 61 >65yrs -2.30 -4.79 -0.42 204.19 1.01 579 22 60 1 FALSE 1.33
non-small cell lung cancer KRAS_G12C SMARCA4 11 19 40-50yrs 0.08 -0.75 0.84 1391.41 1.00 163 10 18 1 FALSE 0.07
non-small cell lung cancer KRAS_G12C SMARCA4 152 119 50-65yrs 0.23 -0.21 0.71 1521.86 1.00 1065 134 101 18 FALSE 0.48
non-small cell lung cancer KRAS_G12C SMARCA4 295 174 >65yrs 0.08 -0.30 0.45 1150.90 1.00 1702 270 149 25 FALSE 0.18
colorectal cancer KRAS_G12C SMARCA4 70 169 Age:overall -2.33 -4.85 -0.51 217.09 1.01 2083 69 168 1 FALSE 1.35
non-small cell lung cancer KRAS_G12C SMARCA4 458 312 Age:overall 0.14 -0.42 0.72 1468.13 1.00 2930 414 268 44 FALSE 0.21
colorectal cancer KRAS_G12C PTPRT 6 18 <40yrs -0.04 -1.03 0.74 422.41 1.00 197 6 18 0 FALSE 0.03
colorectal cancer KRAS_G12C PTPRT 11 39 40-50yrs 0.00 -0.88 0.81 426.90 1.00 411 8 36 3 FALSE 0.00
colorectal cancer KRAS_G12C PTPRT 32 80 50-65yrs -0.03 -0.88 0.76 372.87 1.00 863 29 77 3 FALSE 0.02
colorectal cancer KRAS_G12C PTPRT 23 48 >65yrs -0.06 -1.00 0.70 367.55 1.00 582 23 48 0 FALSE 0.05
non-small cell lung cancer KRAS_G12C PTPRT 12 22 40-50yrs 0.84 -0.19 2.10 923.79 1.00 164 7 17 5 FALSE 0.74
non-small cell lung cancer KRAS_G12C PTPRT 152 152 50-65yrs -0.32 -0.96 0.23 1449.12 1.00 1060 141 141 11 FALSE 0.53
non-small cell lung cancer KRAS_G12C PTPRT 292 175 >65yrs 0.26 -0.16 0.65 1087.30 1.00 1713 262 145 30 FALSE 0.68
colorectal cancer KRAS_G12C PTPRT 72 185 Age:overall -0.03 -0.94 0.73 367.82 1.00 2053 66 179 6 FALSE 0.03
non-small cell lung cancer KRAS_G12C PTPRT 456 349 Age:overall 0.26 -0.58 1.27 1301.02 1.00 2937 410 303 46 FALSE 0.23
colorectal cancer KRAS_G12C HGF 31 24 50-65yrs 0.21 -1.73 1.57 667.17 1.00 915 30 23 1 FALSE 0.09
colorectal cancer KRAS_G12C HGF 23 15 >65yrs 0.25 -1.68 1.61 697.53 1.00 613 22 14 1 FALSE 0.12
non-small cell lung cancer KRAS_G12C HGF 153 78 50-65yrs 0.12 -0.46 0.63 1148.66 1.00 1100 142 67 11 FALSE 0.19
non-small cell lung cancer KRAS_G12C HGF 292 105 >65yrs 0.07 -0.44 0.54 622.04 1.00 1754 277 90 15 FALSE 0.12
colorectal cancer KRAS_G12C HGF 54 39 Age:overall 0.23 -1.75 1.70 664.29 1.00 1528 52 37 2 FALSE 0.10
non-small cell lung cancer KRAS_G12C HGF 445 183 Age:overall 0.10 -0.50 0.70 931.24 1.00 2854 419 157 26 FALSE 0.12
colorectal cancer KRAS_G12C BLM 10 14 40-50yrs -4.83 -11.43 -0.62 317.56 1.02 430 10 14 0 TRUE 1.12
colorectal cancer KRAS_G12C BLM 31 21 50-65yrs -4.85 -11.16 -0.72 307.07 1.03 916 31 21 0 TRUE 1.14
colorectal cancer KRAS_G12C BLM 23 26 >65yrs -4.84 -11.32 -0.66 309.66 1.03 603 23 26 0 TRUE 1.13
colorectal cancer KRAS_G12C BLM 64 61 Age:overall -4.84 -11.23 -0.62 310.81 1.02 1949 64 61 0 TRUE 1.14
colorectal cancer KRAS_G12C PIK3CA 7 42 <40yrs -0.46 -1.22 0.26 64.06 1.05 191 6 41 1 TRUE 0.58
colorectal cancer KRAS_G12C PIK3CA 10 90 40-50yrs -0.39 -1.19 0.43 61.52 1.05 398 6 86 4 TRUE 0.45
colorectal cancer KRAS_G12C PIK3CA 39 213 50-65yrs -0.46 -1.16 0.21 61.66 1.05 849 34 208 5 TRUE 0.68
colorectal cancer KRAS_G12C PIK3CA 25 166 >65yrs -0.52 -1.22 0.19 98.28 1.03 554 23 164 2 TRUE 0.73
non-small cell lung cancer KRAS_G12C PIK3CA 159 90 50-65yrs -0.02 -0.53 0.61 166.36 1.03 1140 146 77 13 TRUE 0.03
non-small cell lung cancer KRAS_G12C PIK3CA 301 140 >65yrs -0.22 -0.70 0.23 606.65 1.00 1763 287 126 14 TRUE 0.44
colorectal cancer KRAS_G12C PIK3CA 81 511 Age:overall -0.46 -1.16 0.25 68.12 1.04 1992 69 499 12 TRUE 0.64
non-small cell lung cancer KRAS_G12C PIK3CA 460 230 Age:overall -0.11 -0.70 0.57 580.34 1.01 2903 433 203 27 TRUE 0.13
non-small cell lung cancer KRAS_G12C GATA3 152 27 50-65yrs 0.78 0.02 1.47 1090.38 1.00 1143 147 22 5 FALSE 1.44
non-small cell lung cancer KRAS_G12C GATA3 291 36 >65yrs 0.87 0.20 1.45 1359.84 1.00 1814 280 25 11 FALSE 2.19
non-small cell lung cancer KRAS_G12C GATA3 443 63 Age:overall 0.81 -0.01 1.57 1358.72 1.00 2957 427 47 16 FALSE 1.23
colorectal cancer KRAS_G12C ESR1 6 12 <40yrs -1.30 -4.30 0.58 602.72 1.01 200 6 12 0 TRUE 0.52
colorectal cancer KRAS_G12C ESR1 31 24 50-65yrs -1.37 -4.54 0.54 586.62 1.01 912 31 24 0 TRUE 0.54
colorectal cancer KRAS_G12C ESR1 23 28 >65yrs -1.19 -4.24 0.59 553.66 1.01 602 22 27 1 TRUE 0.48
non-small cell lung cancer KRAS_G12C ESR1 152 18 50-65yrs -0.54 -1.93 0.55 1414.22 1.00 1147 151 17 1 TRUE 0.42
non-small cell lung cancer KRAS_G12C ESR1 291 34 >65yrs -0.40 -1.46 0.54 1265.88 1.00 1809 287 30 4 TRUE 0.36
colorectal cancer KRAS_G12C ESR1 60 64 Age:overall -1.28 -4.25 0.53 526.83 1.01 1714 59 63 1 TRUE 0.53
non-small cell lung cancer KRAS_G12C ESR1 443 52 Age:overall -0.46 -1.72 0.69 1292.05 1.00 2956 438 47 5 TRUE 0.35
colorectal cancer KRAS_G12C ALK 7 14 <40yrs -0.87 -2.78 0.50 1107.83 1.00 222 7 14 0 TRUE 0.55
colorectal cancer KRAS_G12C ALK 10 25 40-50yrs -0.89 -2.75 0.46 1167.24 1.00 455 10 25 0 TRUE 0.57
colorectal cancer KRAS_G12C ALK 39 44 50-65yrs -0.90 -2.70 0.42 1095.65 1.00 992 39 44 0 TRUE 0.60
colorectal cancer KRAS_G12C ALK 25 32 >65yrs -0.82 -2.69 0.57 1122.21 1.00 668 23 30 2 TRUE 0.51
non-small cell lung cancer KRAS_G12C ALK 159 76 50-65yrs 0.56 0.03 1.02 1078.38 1.00 1159 145 62 14 TRUE 1.66
non-small cell lung cancer KRAS_G12C ALK 300 81 >65yrs 0.49 -0.03 0.90 146.78 1.03 1821 284 65 16 TRUE 1.41
colorectal cancer KRAS_G12C ALK 81 115 Age:overall -0.86 -2.73 0.45 1113.32 1.00 2337 79 113 2 TRUE 0.57
non-small cell lung cancer KRAS_G12C ALK 459 157 Age:overall 0.53 -0.29 1.25 840.74 1.00 2980 429 127 30 TRUE 0.68
colorectal cancer KRAS_G12C RNF43 6 31 <40yrs -1.94 -4.24 -0.18 1629.23 1.00 187 6 31 0 TRUE 1.20
colorectal cancer KRAS_G12C RNF43 10 26 40-50yrs -1.96 -4.27 -0.12 1519.26 1.00 417 10 26 0 TRUE 1.18
colorectal cancer KRAS_G12C RNF43 31 87 50-65yrs -1.51 -3.41 -0.01 1450.82 1.00 869 29 85 2 TRUE 1.09
colorectal cancer KRAS_G12C RNF43 23 123 >65yrs -2.13 -4.31 -0.59 1551.99 1.00 544 23 123 0 TRUE 1.65
colorectal cancer KRAS_G12C RNF43 70 267 Age:overall -1.89 -3.96 -0.43 1557.48 1.00 2017 68 265 2 TRUE 1.46
non-small cell lung cancer KRAS_G12C U2AF1 152 24 50-65yrs 0.46 -0.33 1.11 538.02 1.01 1143 148 20 4 FALSE 0.68
non-small cell lung cancer KRAS_G12C U2AF1 291 51 >65yrs 0.52 -0.09 1.06 488.94 1.01 1799 280 40 11 FALSE 1.11
non-small cell lung cancer KRAS_G12C U2AF1 443 75 Age:overall 0.51 -0.25 1.24 1133.81 1.00 2942 428 60 15 FALSE 0.70
colorectal cancer KRAS_G12C LATS1 29 26 50-65yrs -4.64 -11.14 -0.14 302.86 1.02 889 29 26 0 FALSE 0.97
colorectal cancer KRAS_G12C LATS1 22 14 >65yrs -4.65 -11.14 -0.24 333.41 1.02 597 22 14 0 FALSE 0.98
non-small cell lung cancer KRAS_G12C LATS1 152 27 50-65yrs -0.89 -2.24 0.16 1191.15 1.00 1133 150 25 2 FALSE 0.82
non-small cell lung cancer KRAS_G12C LATS1 291 37 >65yrs -0.98 -2.36 0.00 1033.76 1.00 1795 289 35 2 FALSE 0.97
colorectal cancer KRAS_G12C LATS1 51 40 Age:overall -4.62 -11.01 -0.08 303.90 1.02 1486 51 40 0 FALSE 0.98
non-small cell lung cancer KRAS_G12C LATS1 443 64 Age:overall -0.94 -2.42 0.11 1347.28 1.00 2928 439 60 4 FALSE 0.85
colorectal cancer KRAS_G12C LATS2 29 35 50-65yrs -1.03 -4.28 0.87 1307.31 1.00 879 28 34 1 FALSE 0.38
colorectal cancer KRAS_G12C LATS2 22 21 >65yrs -1.25 -4.66 0.81 1271.27 1.00 591 22 21 0 FALSE 0.37
non-small cell lung cancer KRAS_G12C LATS2 153 24 50-65yrs 0.24 -0.61 1.07 1065.68 1.00 1140 148 19 5 FALSE 0.23
non-small cell lung cancer KRAS_G12C LATS2 291 36 >65yrs 0.02 -0.86 0.76 1097.87 1.00 1798 287 32 4 FALSE 0.02
colorectal cancer KRAS_G12C LATS2 51 56 Age:overall -1.11 -4.42 0.95 1239.05 1.00 1470 50 55 1 FALSE 0.39
non-small cell lung cancer KRAS_G12C LATS2 444 60 Age:overall 0.13 -0.88 1.04 1127.46 1.00 2938 435 51 9 FALSE 0.10
colorectal cancer KRAS_G12C PTEN 7 16 <40yrs -0.99 -2.34 0.18 435.10 1.01 217 7 16 0 TRUE 0.81
colorectal cancer KRAS_G12C PTEN 10 45 40-50yrs -1.00 -2.35 0.17 426.04 1.00 441 10 45 0 TRUE 0.83
colorectal cancer KRAS_G12C PTEN 39 65 50-65yrs -0.93 -2.32 0.24 348.99 1.01 985 37 63 2 TRUE 0.78
colorectal cancer KRAS_G12C PTEN 25 59 >65yrs -0.96 -2.33 0.24 371.24 1.01 655 24 58 1 TRUE 0.81
non-small cell lung cancer KRAS_G12C PTEN 159 40 50-65yrs -0.38 -1.21 0.58 1150.27 1.00 1181 154 35 5 TRUE 0.40
non-small cell lung cancer KRAS_G12C PTEN 300 87 >65yrs -0.76 -1.59 -0.06 1207.74 1.00 1806 295 82 5 TRUE 1.30
colorectal cancer KRAS_G12C PTEN 81 185 Age:overall -0.97 -2.27 0.14 379.37 1.00 2298 78 182 3 TRUE 0.85
non-small cell lung cancer KRAS_G12C PTEN 459 127 Age:overall -0.56 -1.63 0.53 1156.34 1.00 2987 449 117 10 TRUE 0.49
colorectal cancer KRAS_G12C BCOR 6 11 <40yrs -1.92 -4.90 0.11 304.40 1.00 202 6 11 0 FALSE 0.81
colorectal cancer KRAS_G12C BCOR 10 14 40-50yrs -1.91 -4.83 0.13 296.55 1.00 427 10 14 0 FALSE 0.84
colorectal cancer KRAS_G12C BCOR 31 40 50-65yrs -1.93 -4.75 0.03 264.94 1.00 902 31 40 0 FALSE 0.88
colorectal cancer KRAS_G12C BCOR 23 47 >65yrs -1.84 -4.79 0.18 276.28 1.00 589 22 46 1 FALSE 0.81
non-small cell lung cancer KRAS_G12C BCOR 153 46 50-65yrs 0.20 -0.43 0.77 1397.00 1.00 1126 147 40 6 FALSE 0.28
non-small cell lung cancer KRAS_G12C BCOR 294 84 >65yrs 0.26 -0.27 0.75 1030.82 1.01 1772 279 69 15 FALSE 0.51
colorectal cancer KRAS_G12C BCOR 70 112 Age:overall -1.89 -4.76 0.05 267.94 1.00 2120 69 111 1 FALSE 0.86
non-small cell lung cancer KRAS_G12C BCOR 447 130 Age:overall 0.24 -0.40 0.86 1460.38 1.00 2898 426 109 21 FALSE 0.31
colorectal cancer KRAS_G12C CTNNB1 7 20 <40yrs 0.06 -0.96 0.94 1240.15 1.00 211 6 19 1 TRUE 0.05
colorectal cancer KRAS_G12C CTNNB1 10 27 40-50yrs 0.01 -1.07 0.89 1239.78 1.00 449 10 27 0 TRUE 0.00
colorectal cancer KRAS_G12C CTNNB1 39 76 50-65yrs 0.01 -0.95 0.81 1323.79 1.00 965 37 74 2 TRUE 0.01
colorectal cancer KRAS_G12C CTNNB1 25 40 >65yrs 0.11 -0.86 1.00 1303.07 1.00 660 22 37 3 TRUE 0.09
non-small cell lung cancer KRAS_G12C CTNNB1 159 43 50-65yrs -0.62 -1.60 0.14 1273.61 1.00 1174 157 41 2 TRUE 0.79
non-small cell lung cancer KRAS_G12C CTNNB1 301 71 >65yrs -0.44 -1.17 0.23 1440.67 1.00 1821 293 63 8 TRUE 0.65
colorectal cancer KRAS_G12C CTNNB1 81 163 Age:overall 0.04 -0.90 0.86 1269.11 1.00 2285 75 157 6 TRUE 0.03
non-small cell lung cancer KRAS_G12C CTNNB1 460 114 Age:overall -0.53 -1.51 0.27 1260.62 1.00 2995 450 104 10 TRUE 0.60
colorectal cancer KRAS_G12C ARID1A 6 40 <40yrs -1.07 -2.50 0.11 1223.28 1.00 186 6 40 0 TRUE 1.00
colorectal cancer KRAS_G12C ARID1A 10 51 40-50yrs -1.00 -2.40 0.13 961.99 1.00 408 9 50 1 TRUE 0.96
colorectal cancer KRAS_G12C ARID1A 31 114 50-65yrs -1.06 -2.33 0.05 938.86 1.00 851 30 113 1 TRUE 1.10
colorectal cancer KRAS_G12C ARID1A 23 110 >65yrs -1.00 -2.28 0.06 922.03 1.00 553 21 108 2 TRUE 1.04
non-small cell lung cancer KRAS_G12C ARID1A 11 16 40-50yrs -0.03 -1.17 0.77 1238.31 1.00 165 11 16 0 TRUE 0.02
non-small cell lung cancer KRAS_G12C ARID1A 155 117 50-65yrs 0.22 -0.28 0.67 1386.07 1.00 1071 138 100 17 TRUE 0.43
non-small cell lung cancer KRAS_G12C ARID1A 294 149 >65yrs 0.21 -0.20 0.63 1306.64 1.00 1723 269 124 25 TRUE 0.50
colorectal cancer KRAS_G12C ARID1A 70 315 Age:overall -1.03 -2.33 0.06 962.88 1.00 1998 66 311 4 TRUE 1.09
non-small cell lung cancer KRAS_G12C ARID1A 460 282 Age:overall 0.14 -0.61 0.70 1481.98 1.00 2959 418 240 42 TRUE 0.17
colorectal cancer KRAS_G12C PIK3R1 6 11 <40yrs -0.78 -2.66 0.47 328.11 1.00 202 6 11 0 TRUE 0.48
colorectal cancer KRAS_G12C PIK3R1 10 21 40-50yrs -0.76 -2.67 0.58 345.04 1.00 423 9 20 1 TRUE 0.46
colorectal cancer KRAS_G12C PIK3R1 31 48 50-65yrs -0.78 -2.75 0.44 365.11 1.00 896 30 47 1 TRUE 0.49
colorectal cancer KRAS_G12C PIK3R1 23 36 >65yrs -0.79 -2.67 0.51 296.20 1.00 597 23 36 0 TRUE 0.49
non-small cell lung cancer KRAS_G12C PIK3R1 152 18 50-65yrs 0.41 -0.50 1.18 1219.42 1.00 1148 149 15 3 TRUE 0.46
non-small cell lung cancer KRAS_G12C PIK3R1 292 35 >65yrs 0.43 -0.39 1.14 867.83 1.00 1810 285 28 7 TRUE 0.60
colorectal cancer KRAS_G12C PIK3R1 70 116 Age:overall -0.78 -2.68 0.45 327.96 1.00 2118 68 114 2 TRUE 0.49
non-small cell lung cancer KRAS_G12C PIK3R1 444 53 Age:overall 0.41 -0.60 1.23 995.20 1.00 2958 434 43 10 TRUE 0.42
colorectal cancer KRAS_G12C IKZF1 10 13 40-50yrs -0.51 -2.57 0.95 1532.11 1.00 427 10 13 0 TRUE 0.26
colorectal cancer KRAS_G12C IKZF1 31 31 50-65yrs -0.45 -2.32 0.94 1492.05 1.00 909 30 30 1 TRUE 0.23
colorectal cancer KRAS_G12C IKZF1 23 33 >65yrs -0.46 -2.44 0.91 1437.58 1.00 597 22 32 1 TRUE 0.23
non-small cell lung cancer KRAS_G12C IKZF1 152 44 50-65yrs 0.66 -0.10 1.38 1424.11 1.00 1130 142 34 10 TRUE 1.09
non-small cell lung cancer KRAS_G12C IKZF1 291 34 >65yrs -0.22 -1.40 0.64 1304.18 1.00 1807 288 31 3 TRUE 0.18
colorectal cancer KRAS_G12C IKZF1 64 77 Age:overall -0.47 -2.47 0.98 1405.77 1.00 1933 62 75 2 TRUE 0.24
non-small cell lung cancer KRAS_G12C IKZF1 443 78 Age:overall 0.25 -1.22 1.78 1437.96 1.00 2937 430 65 13 TRUE 0.12
colorectal cancer KRAS_G12C TERT 10 23 40-50yrs 0.12 -1.82 1.31 1077.95 1.00 425 10 23 0 TRUE 0.05
colorectal cancer KRAS_G12C TERT 31 39 50-65yrs 0.44 -0.80 1.52 1017.39 1.00 902 27 35 4 TRUE 0.34
colorectal cancer KRAS_G12C TERT 23 27 >65yrs 0.08 -1.86 1.25 1084.19 1.00 601 23 27 0 TRUE 0.03
non-small cell lung cancer KRAS_G12C TERT 154 59 50-65yrs 0.58 0.08 1.07 488.71 1.01 1115 143 48 11 TRUE 1.60
non-small cell lung cancer KRAS_G12C TERT 292 99 >65yrs 0.59 0.14 1.00 425.73 1.01 1766 270 77 22 TRUE 2.01
colorectal cancer KRAS_G12C TERT 64 89 Age:overall 0.22 -1.29 1.35 1234.83 1.00 1928 60 85 4 TRUE 0.12
non-small cell lung cancer KRAS_G12C TERT 446 158 Age:overall 0.58 0.00 1.11 663.23 1.01 2881 413 125 33 TRUE 1.32
colorectal cancer KRAS_G12C FAT1 6 24 <40yrs -4.17 -11.29 -0.14 3.24 1.40 198 6 24 0 FALSE 0.74
colorectal cancer KRAS_G12C FAT1 10 39 40-50yrs -4.17 -11.30 -0.19 3.19 1.40 416 10 39 0 FALSE 0.74
colorectal cancer KRAS_G12C FAT1 31 81 50-65yrs -4.19 -11.23 -0.17 3.18 1.41 883 31 81 0 FALSE 0.74
colorectal cancer KRAS_G12C FAT1 23 83 >65yrs -4.19 -11.35 -0.15 3.20 1.40 566 23 83 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C FAT1 152 103 50-65yrs 0.26 -0.20 0.66 180.54 1.00 1082 138 89 14 FALSE 0.55
non-small cell lung cancer KRAS_G12C FAT1 295 194 >65yrs 0.31 -0.06 0.66 199.31 1.01 1696 261 160 34 FALSE 1.04
colorectal cancer KRAS_G12C FAT1 70 227 Age:overall -4.18 -11.31 -0.19 3.21 1.40 2063 70 227 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C FAT1 447 297 Age:overall 0.29 -0.23 0.80 538.90 1.00 2778 399 249 48 FALSE 0.50
colorectal cancer KRAS_G12C FGFR4 31 17 50-65yrs -4.60 -11.55 -0.07 494.90 1.00 920 31 17 0 TRUE 0.87
colorectal cancer KRAS_G12C FGFR4 23 21 >65yrs -4.62 -11.63 -0.19 537.64 1.00 609 23 21 0 TRUE 0.88
colorectal cancer KRAS_G12C FGFR4 54 38 Age:overall -4.52 -11.41 0.00 503.58 1.00 1529 54 38 0 TRUE 0.87
colorectal cancer KRAS_G12C CIC 6 15 <40yrs -1.08 -3.19 0.38 1234.10 1.00 199 6 15 0 TRUE 0.64
colorectal cancer KRAS_G12C CIC 10 25 40-50yrs -1.06 -3.10 0.36 1239.64 1.00 422 10 25 0 TRUE 0.63
colorectal cancer KRAS_G12C CIC 31 39 50-65yrs -0.84 -2.63 0.56 1407.47 1.00 905 29 37 2 TRUE 0.51
colorectal cancer KRAS_G12C CIC 23 58 >65yrs -1.16 -3.10 0.19 953.46 1.01 582 23 58 0 TRUE 0.75
non-small cell lung cancer KRAS_G12C CIC 152 21 50-65yrs 0.09 -0.94 0.98 1331.61 1.00 1148 149 18 3 TRUE 0.07
non-small cell lung cancer KRAS_G12C CIC 295 66 >65yrs 0.12 -0.56 0.73 1301.97 1.00 1785 285 56 10 TRUE 0.14
colorectal cancer KRAS_G12C CIC 70 137 Age:overall -1.04 -2.96 0.28 1235.69 1.00 2108 68 135 2 TRUE 0.67
non-small cell lung cancer KRAS_G12C CIC 447 87 Age:overall 0.10 -0.94 1.14 1538.10 1.00 2933 434 74 13 TRUE 0.06
colorectal cancer KRAS_G12C KDM6A 10 11 40-50yrs -4.55 -11.50 0.15 71.09 1.05 430 10 11 0 FALSE 0.94
colorectal cancer KRAS_G12C KDM6A 31 26 50-65yrs -4.55 -11.52 0.12 66.80 1.05 911 31 26 0 FALSE 0.94
colorectal cancer KRAS_G12C KDM6A 23 20 >65yrs -4.55 -11.37 0.10 70.38 1.05 608 23 20 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C KDM6A 152 27 50-65yrs -0.45 -1.51 0.48 850.22 1.00 1140 150 25 2 FALSE 0.45
non-small cell lung cancer KRAS_G12C KDM6A 291 33 >65yrs -0.37 -1.26 0.47 482.01 1.01 1810 287 29 4 FALSE 0.40
colorectal cancer KRAS_G12C KDM6A 64 57 Age:overall -4.55 -11.58 0.11 68.37 1.05 1949 64 57 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C KDM6A 443 60 Age:overall -0.39 -1.48 0.62 762.40 1.01 2950 437 54 6 FALSE 0.35
colorectal cancer KRAS_G12C NCOR1 6 12 <40yrs -5.29 -13.56 -0.95 238.65 1.01 203 6 12 0 FALSE 1.06
colorectal cancer KRAS_G12C NCOR1 10 22 40-50yrs -5.28 -13.71 -1.01 240.79 1.01 423 10 22 0 FALSE 1.05
colorectal cancer KRAS_G12C NCOR1 31 56 50-65yrs -5.28 -13.32 -1.01 240.35 1.01 890 31 56 0 FALSE 1.05
colorectal cancer KRAS_G12C NCOR1 23 45 >65yrs -5.28 -13.78 -0.99 242.02 1.01 589 23 45 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C NCOR1 153 41 50-65yrs 0.15 -0.55 0.84 1464.53 1.00 1132 147 35 6 FALSE 0.17
non-small cell lung cancer KRAS_G12C NCOR1 292 56 >65yrs 0.08 -0.59 0.67 1476.42 1.00 1793 284 48 8 FALSE 0.09
colorectal cancer KRAS_G12C NCOR1 70 135 Age:overall -5.28 -13.46 -0.99 239.38 1.01 2105 70 135 0 FALSE 1.06
non-small cell lung cancer KRAS_G12C NCOR1 445 97 Age:overall 0.11 -0.67 0.85 1469.11 1.00 2925 431 83 14 FALSE 0.11
colorectal cancer KRAS_G12C POLE 6 22 <40yrs -5.09 -11.94 -1.09 516.12 1.01 196 6 22 0 TRUE 1.17
colorectal cancer KRAS_G12C POLE 10 23 40-50yrs -5.08 -11.86 -1.13 521.38 1.01 422 10 23 0 TRUE 1.17
colorectal cancer KRAS_G12C POLE 31 51 50-65yrs -5.08 -11.94 -1.09 542.63 1.01 895 31 51 0 TRUE 1.16
colorectal cancer KRAS_G12C POLE 23 45 >65yrs -5.08 -11.88 -1.07 503.92 1.01 588 23 45 0 TRUE 1.17
non-small cell lung cancer KRAS_G12C POLE 152 56 50-65yrs 0.71 0.18 1.22 661.89 1.00 1122 140 44 12 TRUE 2.23
non-small cell lung cancer KRAS_G12C POLE 292 75 >65yrs 0.67 0.19 1.10 448.41 1.01 1784 275 58 17 TRUE 2.26
colorectal cancer KRAS_G12C POLE 70 141 Age:overall -5.08 -11.87 -1.10 502.61 1.01 2101 70 141 0 TRUE 1.17
non-small cell lung cancer KRAS_G12C POLE 444 131 Age:overall 0.70 0.07 1.37 983.24 1.00 2906 415 102 29 TRUE 1.37
non-small cell lung cancer KRAS_G12C CUL3 152 24 50-65yrs 0.37 -0.26 1.13 12.21 1.09 1146 148 20 4 FALSE 0.54
non-small cell lung cancer KRAS_G12C CUL3 292 50 >65yrs 0.41 -0.04 1.05 5.71 1.17 1802 281 39 11 FALSE 0.74
non-small cell lung cancer KRAS_G12C CUL3 444 74 Age:overall 0.39 -0.26 1.18 13.23 1.08 2948 429 59 15 FALSE 0.52
colorectal cancer KRAS_G12C ABL1 10 14 40-50yrs -4.68 -11.74 -0.32 949.74 1.00 464 10 14 0 TRUE 0.95
colorectal cancer KRAS_G12C ABL1 39 29 50-65yrs -4.68 -11.66 -0.35 967.37 1.00 1010 39 29 0 TRUE 0.95
colorectal cancer KRAS_G12C ABL1 25 24 >65yrs -4.69 -11.56 -0.36 940.37 1.00 672 25 24 0 TRUE 0.96
colorectal cancer KRAS_G12C ABL1 74 67 Age:overall -4.67 -11.39 -0.32 938.02 1.00 2146 74 67 0 TRUE 0.96
colorectal cancer KRAS_G12C FOXP1 6 12 <40yrs -1.17 -4.04 0.79 776.96 1.00 202 5 11 1 FALSE 0.48
colorectal cancer KRAS_G12C FOXP1 10 17 40-50yrs -1.30 -4.24 0.65 911.70 1.00 425 10 17 0 FALSE 0.55
colorectal cancer KRAS_G12C FOXP1 31 27 50-65yrs -1.31 -4.08 0.56 862.95 1.00 911 31 27 0 FALSE 0.58
colorectal cancer KRAS_G12C FOXP1 23 14 >65yrs -1.28 -4.26 0.64 838.89 1.00 612 23 14 0 FALSE 0.56
colorectal cancer KRAS_G12C FOXP1 70 70 Age:overall -1.26 -4.10 0.61 840.71 1.00 2150 69 69 1 FALSE 0.55
colorectal cancer KRAS_G12C NOTCH2 29 24 50-65yrs -4.47 -11.48 -0.14 678.73 1.00 887 29 24 0 TRUE 0.90
colorectal cancer KRAS_G12C NOTCH2 22 31 >65yrs -4.54 -11.45 -0.26 716.22 1.00 586 22 31 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C NOTCH2 152 43 50-65yrs -0.32 -1.18 0.38 1475.32 1.00 1126 149 40 3 TRUE 0.37
non-small cell lung cancer KRAS_G12C NOTCH2 291 67 >65yrs -0.20 -0.88 0.40 1297.25 1.00 1774 282 58 9 TRUE 0.26
colorectal cancer KRAS_G12C NOTCH2 51 55 Age:overall -4.41 -11.15 -0.12 695.83 1.00 1473 51 55 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C NOTCH2 443 110 Age:overall -0.26 -1.15 0.55 1499.52 1.00 2900 431 98 12 TRUE 0.24
non-small cell lung cancer KRAS_G12C DDR2 152 39 50-65yrs 0.17 -0.48 0.83 1233.07 1.00 1130 146 33 6 TRUE 0.20
non-small cell lung cancer KRAS_G12C DDR2 291 56 >65yrs 0.10 -0.54 0.69 1254.60 1.00 1789 283 48 8 TRUE 0.13
non-small cell lung cancer KRAS_G12C DDR2 443 95 Age:overall 0.14 -0.60 0.90 1375.94 1.00 2919 429 81 14 TRUE 0.14
colorectal cancer KRAS_G12C TGFBR2 10 18 40-50yrs -1.55 -4.35 0.55 831.06 1.00 424 9 17 1 TRUE 0.64
colorectal cancer KRAS_G12C TGFBR2 31 42 50-65yrs -1.79 -4.74 0.27 881.92 1.00 897 31 42 0 TRUE 0.80
colorectal cancer KRAS_G12C TGFBR2 23 46 >65yrs -1.80 -4.70 0.26 944.05 1.00 582 23 46 0 TRUE 0.80
non-small cell lung cancer KRAS_G12C TGFBR2 153 28 50-65yrs 0.77 -0.04 1.51 1318.78 1.00 1144 146 21 7 TRUE 1.30
non-small cell lung cancer KRAS_G12C TGFBR2 291 26 >65yrs 0.50 -0.30 1.24 1513.31 1.00 1817 286 21 5 TRUE 0.68
colorectal cancer KRAS_G12C TGFBR2 64 106 Age:overall -1.72 -4.47 0.26 885.90 1.00 1903 63 105 1 TRUE 0.77
non-small cell lung cancer KRAS_G12C TGFBR2 444 54 Age:overall 0.62 -0.54 1.63 1515.24 1.01 2961 432 42 12 TRUE 0.60
colorectal cancer KRAS_G12C SMO 10 14 40-50yrs -4.94 -11.26 -0.49 142.26 1.03 462 10 14 0 TRUE 1.04
colorectal cancer KRAS_G12C SMO 39 29 50-65yrs -4.94 -11.34 -0.53 141.77 1.03 1009 39 29 0 TRUE 1.04
colorectal cancer KRAS_G12C SMO 25 21 >65yrs -4.94 -11.18 -0.57 144.73 1.03 676 25 21 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C SMO 159 25 50-65yrs 0.22 -0.62 0.97 1136.34 1.00 1195 155 21 4 TRUE 0.23
non-small cell lung cancer KRAS_G12C SMO 300 45 >65yrs 0.17 -0.58 0.82 1119.34 1.00 1846 293 38 7 TRUE 0.20
colorectal cancer KRAS_G12C SMO 74 64 Age:overall -4.93 -11.20 -0.53 140.41 1.03 2147 74 64 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C SMO 459 70 Age:overall 0.20 -0.66 1.03 1157.47 1.00 3041 448 59 11 TRUE 0.20
colorectal cancer KRAS_G12C RPS6KA4 29 28 50-65yrs -5.08 -12.05 -0.22 23.80 1.13 883 29 28 0 FALSE 0.93
colorectal cancer KRAS_G12C RPS6KA4 22 16 >65yrs -5.04 -12.46 -0.20 24.13 1.13 596 22 16 0 FALSE 0.91
colorectal cancer KRAS_G12C RPS6KA4 51 44 Age:overall -5.04 -12.10 -0.20 23.27 1.13 1479 51 44 0 FALSE 0.92
colorectal cancer KRAS_G12C KMT2A 6 22 <40yrs -1.17 -3.15 0.29 928.52 1.00 195 6 22 0 FALSE 0.74
colorectal cancer KRAS_G12C KMT2A 10 22 40-50yrs -1.19 -3.02 0.22 834.68 1.00 425 10 22 0 FALSE 0.79
colorectal cancer KRAS_G12C KMT2A 31 53 50-65yrs -1.24 -3.13 0.14 760.58 1.00 894 31 53 0 FALSE 0.87
colorectal cancer KRAS_G12C KMT2A 23 51 >65yrs -1.03 -2.77 0.35 691.63 1.00 588 21 49 2 FALSE 0.69
non-small cell lung cancer KRAS_G12C KMT2A 152 33 50-65yrs 0.17 -0.56 0.97 445.72 1.01 1136 146 27 6 FALSE 0.17
non-small cell lung cancer KRAS_G12C KMT2A 291 75 >65yrs -0.03 -0.69 0.60 558.61 1.00 1777 282 66 9 FALSE 0.04
colorectal cancer KRAS_G12C KMT2A 70 148 Age:overall -1.16 -2.96 0.16 777.75 1.00 2102 68 146 2 FALSE 0.82
non-small cell lung cancer KRAS_G12C KMT2A 443 108 Age:overall 0.06 -0.75 0.92 804.49 1.00 2913 428 93 15 FALSE 0.05
colorectal cancer KRAS_G12C JAK3 39 28 50-65yrs -1.06 -3.91 0.82 912.06 1.00 1009 38 27 1 TRUE 0.41
colorectal cancer KRAS_G12C JAK3 25 22 >65yrs -1.26 -4.76 0.74 783.16 1.00 677 25 22 0 TRUE 0.42
non-small cell lung cancer KRAS_G12C JAK3 159 33 50-65yrs 0.48 -0.20 1.11 726.16 1.00 1190 152 26 7 TRUE 0.87
non-small cell lung cancer KRAS_G12C JAK3 301 48 >65yrs 0.39 -0.31 0.92 271.36 1.03 1843 293 40 8 TRUE 0.67
colorectal cancer KRAS_G12C JAK3 64 50 Age:overall -1.17 -4.15 0.84 908.28 1.00 1686 63 49 1 TRUE 0.43
non-small cell lung cancer KRAS_G12C JAK3 460 81 Age:overall 0.42 -0.38 1.12 927.77 1.00 3033 445 66 15 TRUE 0.52
non-small cell lung cancer KRAS_G12C PAK7 152 45 50-65yrs -0.01 -0.70 0.71 613.05 1.01 1122 145 38 7 FALSE 0.01
non-small cell lung cancer KRAS_G12C PAK7 291 81 >65yrs -0.21 -0.91 0.43 680.04 1.00 1763 283 73 8 FALSE 0.29
non-small cell lung cancer KRAS_G12C PAK7 443 126 Age:overall -0.10 -0.88 0.66 857.23 1.00 2885 428 111 15 FALSE 0.09
non-small cell lung cancer KRAS_G12C STAG2 152 38 50-65yrs 0.10 -0.64 0.74 1390.63 1.00 1134 148 34 4 TRUE 0.11
non-small cell lung cancer KRAS_G12C STAG2 291 61 >65yrs 0.22 -0.41 0.78 1538.70 1.00 1788 280 50 11 TRUE 0.32
non-small cell lung cancer KRAS_G12C STAG2 443 99 Age:overall 0.16 -0.64 0.88 1408.38 1.00 2922 428 84 15 TRUE 0.17
colorectal cancer KRAS_G12C BRCA2 6 26 <40yrs -1.27 -3.11 0.17 932.19 1.00 200 5 25 1 TRUE 0.89
colorectal cancer KRAS_G12C BRCA2 10 38 40-50yrs -1.39 -3.25 0.03 1230.02 1.00 418 10 38 0 TRUE 0.99
colorectal cancer KRAS_G12C BRCA2 31 61 50-65yrs -1.42 -3.19 -0.13 893.97 1.00 897 31 61 0 TRUE 1.10
colorectal cancer KRAS_G12C BRCA2 23 65 >65yrs -1.34 -3.13 -0.01 699.28 1.00 574 22 64 1 TRUE 1.00
non-small cell lung cancer KRAS_G12C BRCA2 152 58 50-65yrs 0.30 -0.35 1.02 1489.79 1.00 1119 141 47 11 TRUE 0.42
non-small cell lung cancer KRAS_G12C BRCA2 291 72 >65yrs -0.14 -0.91 0.46 1314.52 1.00 1781 284 65 7 TRUE 0.16
colorectal cancer KRAS_G12C BRCA2 70 190 Age:overall -1.35 -3.11 -0.04 953.19 1.00 2089 68 188 2 TRUE 1.05
non-small cell lung cancer KRAS_G12C BRCA2 443 130 Age:overall 0.09 -0.81 0.99 1441.00 1.00 2900 425 112 18 TRUE 0.07
colorectal cancer KRAS_G12C NOTCH3 6 22 <40yrs -5.68 -13.65 -1.45 78.04 1.03 195 6 22 0 TRUE 1.23
colorectal cancer KRAS_G12C NOTCH3 10 28 40-50yrs -5.68 -13.70 -1.43 78.73 1.03 416 10 28 0 TRUE 1.23
colorectal cancer KRAS_G12C NOTCH3 31 71 50-65yrs -5.69 -13.69 -1.46 77.74 1.03 881 31 71 0 TRUE 1.23
colorectal cancer KRAS_G12C NOTCH3 23 79 >65yrs -5.68 -13.70 -1.41 78.99 1.03 564 23 79 0 TRUE 1.22
non-small cell lung cancer KRAS_G12C NOTCH3 152 44 50-65yrs -0.03 -0.70 0.64 821.51 1.00 1128 146 38 6 TRUE 0.03
non-small cell lung cancer KRAS_G12C NOTCH3 291 78 >65yrs -0.12 -0.75 0.44 806.96 1.00 1774 282 69 9 TRUE 0.16
colorectal cancer KRAS_G12C NOTCH3 70 200 Age:overall -5.67 -13.68 -1.34 78.39 1.03 2056 70 200 0 TRUE 1.23
non-small cell lung cancer KRAS_G12C NOTCH3 443 122 Age:overall -0.07 -0.80 0.62 1325.36 1.00 2902 428 107 15 TRUE 0.07
colorectal cancer KRAS_G12C NOTCH4 10 19 40-50yrs -0.49 -1.93 0.91 43.22 1.08 410 9 18 1 TRUE 0.26
colorectal cancer KRAS_G12C NOTCH4 29 43 50-65yrs -0.48 -1.85 0.80 33.51 1.10 872 27 41 2 TRUE 0.27
colorectal cancer KRAS_G12C NOTCH4 22 48 >65yrs -0.62 -2.03 0.66 56.15 1.06 571 22 48 0 TRUE 0.37
non-small cell lung cancer KRAS_G12C NOTCH4 152 49 50-65yrs -0.31 -1.06 0.34 1453.31 1.00 1115 148 45 4 TRUE 0.42
non-small cell lung cancer KRAS_G12C NOTCH4 291 84 >65yrs -0.24 -0.87 0.30 1432.15 1.00 1759 281 74 10 TRUE 0.38
colorectal cancer KRAS_G12C NOTCH4 66 122 Age:overall -0.54 -1.85 0.69 41.85 1.08 2049 63 119 3 TRUE 0.32
non-small cell lung cancer KRAS_G12C NOTCH4 443 133 Age:overall -0.28 -1.07 0.39 1426.60 1.00 2874 429 119 14 TRUE 0.31
colorectal cancer KRAS_G12C FGFR3 39 25 50-65yrs -4.43 -11.25 -0.42 707.35 1.00 1012 39 25 0 TRUE 0.95
colorectal cancer KRAS_G12C FGFR3 25 24 >65yrs -4.40 -10.71 -0.41 696.42 1.00 674 25 24 0 TRUE 0.95
colorectal cancer KRAS_G12C FGFR3 64 49 Age:overall -4.36 -10.87 -0.38 715.43 1.00 1686 64 49 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C MAP3K13 152 21 50-65yrs -0.66 -2.02 0.41 713.10 1.00 1138 150 19 2 FALSE 0.56
non-small cell lung cancer KRAS_G12C MAP3K13 291 30 >65yrs -0.75 -2.08 0.21 852.67 1.00 1803 289 28 2 FALSE 0.69
non-small cell lung cancer KRAS_G12C MAP3K13 443 51 Age:overall -0.71 -2.08 0.39 750.16 1.00 2941 439 47 4 FALSE 0.57
colorectal cancer KRAS_G12C IGF1R 6 11 <40yrs -5.01 -11.24 -0.86 396.79 1.01 203 6 11 0 TRUE 1.30
colorectal cancer KRAS_G12C IGF1R 10 11 40-50yrs -5.02 -11.26 -0.87 405.44 1.01 430 10 11 0 TRUE 1.31
colorectal cancer KRAS_G12C IGF1R 31 25 50-65yrs -5.02 -11.12 -0.90 407.97 1.01 914 31 25 0 TRUE 1.31
colorectal cancer KRAS_G12C IGF1R 23 33 >65yrs -5.01 -11.34 -0.96 437.48 1.01 597 23 33 0 TRUE 1.30
non-small cell lung cancer KRAS_G12C IGF1R 152 29 50-65yrs 0.44 -0.59 1.28 1168.55 1.00 1138 148 25 4 TRUE 0.45
non-small cell lung cancer KRAS_G12C IGF1R 291 23 >65yrs 0.94 0.14 1.81 1531.61 1.00 1823 283 15 8 TRUE 1.59
colorectal cancer KRAS_G12C IGF1R 70 80 Age:overall -5.00 -11.12 -0.92 415.00 1.01 2144 70 80 0 TRUE 1.32
non-small cell lung cancer KRAS_G12C IGF1R 443 52 Age:overall 0.68 -0.71 1.95 1473.69 1.00 2961 431 40 12 TRUE 0.50
non-small cell lung cancer KRAS_G12C KEAP1 11 22 40-50yrs 0.66 0.07 1.63 1142.17 1.00 162 7 18 4 FALSE 1.03
non-small cell lung cancer KRAS_G12C KEAP1 154 203 50-65yrs 0.52 0.15 0.87 1405.08 1.00 1001 120 169 34 FALSE 2.32
non-small cell lung cancer KRAS_G12C KEAP1 294 312 >65yrs 0.47 0.16 0.77 1323.37 1.00 1594 236 254 58 FALSE 2.75
non-small cell lung cancer KRAS_G12C KEAP1 459 537 Age:overall 0.55 0.06 1.16 1400.30 1.00 2757 363 441 96 FALSE 1.21
colorectal cancer KRAS_G12C KDM5C 31 24 50-65yrs -1.25 -5.25 0.86 964.12 1.00 915 31 24 0 FALSE 0.37
colorectal cancer KRAS_G12C KDM5C 23 26 >65yrs -0.87 -3.71 1.06 1068.67 1.00 605 22 25 1 FALSE 0.32
non-small cell lung cancer KRAS_G12C KDM5C 153 43 50-65yrs 0.13 -0.59 0.85 1277.01 1.00 1129 146 36 7 FALSE 0.14
non-small cell lung cancer KRAS_G12C KDM5C 291 59 >65yrs -0.02 -0.74 0.59 1113.76 1.00 1787 284 52 7 FALSE 0.02
colorectal cancer KRAS_G12C KDM5C 54 50 Age:overall -1.02 -4.21 1.09 1128.79 1.00 1520 53 49 1 FALSE 0.34
non-small cell lung cancer KRAS_G12C KDM5C 444 102 Age:overall 0.05 -0.77 0.86 1083.83 1.00 2916 430 88 14 FALSE 0.05
non-small cell lung cancer KRAS_G12C CDKN2A 11 18 40-50yrs -0.51 -2.03 0.52 1353.88 1.00 175 11 18 0 TRUE 0.38
non-small cell lung cancer KRAS_G12C CDKN2A 161 114 50-65yrs -0.48 -1.21 0.10 1232.69 1.00 1115 153 106 8 TRUE 0.85
non-small cell lung cancer KRAS_G12C CDKN2A 302 141 >65yrs 0.02 -0.45 0.49 1317.25 1.00 1768 280 119 22 TRUE 0.02
non-small cell lung cancer KRAS_G12C CDKN2A 474 273 Age:overall -0.30 -1.16 0.50 1494.68 1.00 3058 444 243 30 TRUE 0.32
colorectal cancer KRAS_G12C EPHB1 6 13 <40yrs -4.86 -11.71 -0.63 482.28 1.01 199 6 13 0 FALSE 1.00
colorectal cancer KRAS_G12C EPHB1 31 31 50-65yrs -4.88 -11.73 -0.58 512.25 1.01 906 31 31 0 FALSE 1.01
colorectal cancer KRAS_G12C EPHB1 23 28 >65yrs -4.87 -11.76 -0.56 468.93 1.01 600 23 28 0 FALSE 1.00
non-small cell lung cancer KRAS_G12C EPHB1 152 54 50-65yrs -0.38 -1.41 0.30 1145.40 1.00 1121 149 51 3 FALSE 0.42
non-small cell lung cancer KRAS_G12C EPHB1 292 99 >65yrs -0.05 -0.61 0.49 1536.07 1.00 1757 277 84 15 FALSE 0.06
colorectal cancer KRAS_G12C EPHB1 60 72 Age:overall -4.85 -11.69 -0.58 504.65 1.01 1705 60 72 0 FALSE 1.01
non-small cell lung cancer KRAS_G12C EPHB1 444 153 Age:overall -0.21 -1.14 0.57 1283.54 1.00 2878 426 135 18 FALSE 0.20
colorectal cancer KRAS_G12C IRS2 6 13 <40yrs -1.55 -4.53 0.41 1394.78 1.00 199 6 13 0 FALSE 0.69
colorectal cancer KRAS_G12C IRS2 10 19 40-50yrs -1.53 -4.45 0.37 1393.93 1.00 423 10 19 0 FALSE 0.69
colorectal cancer KRAS_G12C IRS2 31 30 50-65yrs -1.49 -4.35 0.41 1346.69 1.00 911 30 29 1 FALSE 0.67
colorectal cancer KRAS_G12C IRS2 23 25 >65yrs -1.55 -4.49 0.37 1333.68 1.00 604 23 25 0 FALSE 0.71
non-small cell lung cancer KRAS_G12C IRS2 152 25 50-65yrs -0.55 -1.58 0.41 1404.60 1.00 1140 150 23 2 FALSE 0.57
non-small cell lung cancer KRAS_G12C IRS2 291 55 >65yrs -0.53 -1.45 0.21 1379.65 1.00 1790 286 50 5 FALSE 0.67
colorectal cancer KRAS_G12C IRS2 70 87 Age:overall -1.53 -4.43 0.36 1362.53 1.00 2137 69 86 1 FALSE 0.70
non-small cell lung cancer KRAS_G12C IRS2 443 80 Age:overall -0.54 -1.58 0.36 1455.65 1.00 2930 436 73 7 FALSE 0.52
colorectal cancer KRAS_G12C FANCA 6 11 <40yrs -4.86 -11.66 -0.46 377.56 1.01 200 6 11 0 TRUE 1.03
colorectal cancer KRAS_G12C FANCA 10 11 40-50yrs -4.87 -11.80 -0.45 398.55 1.01 430 10 11 0 TRUE 1.03
colorectal cancer KRAS_G12C FANCA 31 31 50-65yrs -4.88 -11.81 -0.57 406.39 1.01 911 31 31 0 TRUE 1.05
colorectal cancer KRAS_G12C FANCA 23 12 >65yrs -4.86 -11.71 -0.48 362.85 1.01 614 23 12 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C FANCA 152 29 50-65yrs 0.13 -0.75 1.00 1602.56 1.00 1139 147 24 5 TRUE 0.12
non-small cell lung cancer KRAS_G12C FANCA 291 36 >65yrs -0.06 -0.93 0.69 1489.11 1.00 1807 287 32 4 TRUE 0.05
colorectal cancer KRAS_G12C FANCA 70 65 Age:overall -4.86 -11.78 -0.57 375.40 1.01 2155 70 65 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C FANCA 443 65 Age:overall 0.03 -1.00 0.95 1521.15 1.00 2946 434 56 9 TRUE 0.02
non-small cell lung cancer KRAS_G12C IL7R 153 38 50-65yrs -0.21 -1.00 0.52 864.25 1.01 1133 149 34 4 FALSE 0.22
non-small cell lung cancer KRAS_G12C IL7R 291 49 >65yrs -0.21 -0.97 0.48 861.73 1.00 1798 285 43 6 FALSE 0.24
non-small cell lung cancer KRAS_G12C IL7R 444 87 Age:overall -0.20 -1.05 0.57 836.59 1.01 2931 434 77 10 FALSE 0.19
colorectal cancer KRAS_G12C PIK3CB 10 21 40-50yrs -1.21 -4.16 0.85 1327.54 1.00 410 10 21 0 FALSE 0.46
colorectal cancer KRAS_G12C PIK3CB 29 17 50-65yrs -1.26 -4.22 0.81 1381.97 1.00 898 29 17 0 FALSE 0.48
colorectal cancer KRAS_G12C PIK3CB 22 22 >65yrs -0.99 -3.79 0.95 1375.94 1.00 593 21 21 1 FALSE 0.38
colorectal cancer KRAS_G12C PIK3CB 61 60 Age:overall -1.16 -3.88 0.87 1350.35 1.00 1901 60 59 1 FALSE 0.47
colorectal cancer KRAS_G12C ERBB3 6 13 <40yrs -0.43 -2.07 0.79 1257.17 1.00 200 6 13 0 TRUE 0.27
colorectal cancer KRAS_G12C ERBB3 10 14 40-50yrs -0.44 -1.95 0.82 1348.21 1.00 428 10 14 0 TRUE 0.27
colorectal cancer KRAS_G12C ERBB3 31 48 50-65yrs -0.35 -1.84 0.78 1371.68 1.00 894 29 46 2 TRUE 0.23
colorectal cancer KRAS_G12C ERBB3 23 47 >65yrs -0.45 -1.98 0.74 1152.01 1.00 587 22 46 1 TRUE 0.29
colorectal cancer KRAS_G12C ERBB3 70 122 Age:overall -0.42 -1.85 0.69 1212.14 1.00 2109 67 119 3 TRUE 0.28
colorectal cancer KRAS_G12C SMAD4 7 33 <40yrs 0.15 -0.50 0.72 262.57 1.01 200 6 32 1 TRUE 0.20
colorectal cancer KRAS_G12C SMAD4 10 68 40-50yrs 0.14 -0.50 0.68 253.70 1.01 417 8 66 2 TRUE 0.19
colorectal cancer KRAS_G12C SMAD4 39 151 50-65yrs 0.14 -0.48 0.69 209.31 1.01 897 34 146 5 TRUE 0.19
colorectal cancer KRAS_G12C SMAD4 25 108 >65yrs 0.16 -0.49 0.70 225.44 1.01 606 20 103 5 TRUE 0.22
non-small cell lung cancer KRAS_G12C SMAD4 159 45 50-65yrs -0.44 -1.74 0.35 1294.09 1.00 1175 157 43 2 TRUE 0.39
non-small cell lung cancer KRAS_G12C SMAD4 300 64 >65yrs 0.00 -0.63 0.59 1094.45 1.00 1830 289 53 11 TRUE 0.00
colorectal cancer KRAS_G12C SMAD4 81 360 Age:overall 0.15 -0.45 0.68 224.15 1.01 2120 68 347 13 TRUE 0.21
non-small cell lung cancer KRAS_G12C SMAD4 459 109 Age:overall -0.21 -1.43 0.77 1373.94 1.00 3005 446 96 13 TRUE 0.16
colorectal cancer KRAS_G12C ATM 7 24 <40yrs -0.90 -2.34 0.31 1388.11 1.00 214 7 24 0 TRUE 0.74
colorectal cancer KRAS_G12C ATM 10 33 40-50yrs -0.88 -2.29 0.29 1434.53 1.00 450 10 33 0 TRUE 0.76
colorectal cancer KRAS_G12C ATM 39 87 50-65yrs -0.90 -2.23 0.15 1470.61 1.00 967 38 86 1 TRUE 0.87
colorectal cancer KRAS_G12C ATM 26 87 >65yrs -0.73 -2.04 0.33 1486.04 1.00 630 23 84 3 TRUE 0.65
non-small cell lung cancer KRAS_G12C ATM 164 100 50-65yrs 1.27 0.86 1.73 946.39 1.00 1152 131 67 33 TRUE 7.91
non-small cell lung cancer KRAS_G12C ATM 308 179 >65yrs 0.93 0.55 1.28 176.33 1.02 1764 263 134 45 TRUE 6.00
colorectal cancer KRAS_G12C ATM 82 231 Age:overall -0.85 -2.13 0.20 1439.83 1.00 2261 78 227 4 TRUE 0.81
non-small cell lung cancer KRAS_G12C ATM 472 279 Age:overall 1.09 0.34 1.80 1196.18 1.00 2916 394 201 78 TRUE 2.37
colorectal cancer KRAS_G12C RB1 10 15 40-50yrs -1.21 -4.12 0.70 1068.38 1.00 462 10 15 0 TRUE 0.47
colorectal cancer KRAS_G12C RB1 39 20 50-65yrs -1.27 -4.28 0.64 1116.66 1.00 1020 39 20 0 TRUE 0.50
colorectal cancer KRAS_G12C RB1 25 24 >65yrs -1.10 -3.94 0.75 1121.06 1.00 677 24 23 1 TRUE 0.44
non-small cell lung cancer KRAS_G12C RB1 159 82 50-65yrs -0.83 -1.57 -0.21 1325.66 1.00 1139 154 77 5 TRUE 1.85
non-small cell lung cancer KRAS_G12C RB1 300 131 >65yrs -0.82 -1.45 -0.26 1186.85 1.00 1764 291 122 9 TRUE 2.23
colorectal cancer KRAS_G12C RB1 74 59 Age:overall -1.19 -3.99 0.64 1115.75 1.00 2159 73 58 1 TRUE 0.48
non-small cell lung cancer KRAS_G12C RB1 459 213 Age:overall -0.82 -1.60 -0.14 1273.92 1.00 2903 445 199 14 TRUE 1.54
colorectal cancer KRAS_G12C KMT2D 6 41 <40yrs -2.17 -4.28 -0.53 1456.81 1.00 185 6 41 0 FALSE 1.71
colorectal cancer KRAS_G12C KMT2D 10 52 40-50yrs -1.94 -4.00 -0.36 1263.13 1.00 407 9 51 1 FALSE 1.49
colorectal cancer KRAS_G12C KMT2D 31 122 50-65yrs -2.05 -4.04 -0.61 1388.41 1.00 855 30 121 1 FALSE 1.84
colorectal cancer KRAS_G12C KMT2D 23 173 >65yrs -2.30 -4.21 -0.92 1395.01 1.00 533 23 173 0 FALSE 2.20
non-small cell lung cancer KRAS_G12C KMT2D 154 130 50-65yrs -0.17 -0.67 0.24 1107.92 1.00 1065 142 118 12 FALSE 0.35
non-small cell lung cancer KRAS_G12C KMT2D 291 188 >65yrs -0.10 -0.49 0.30 926.63 1.00 1698 266 163 25 FALSE 0.22
colorectal cancer KRAS_G12C KMT2D 70 388 Age:overall -2.11 -4.08 -0.76 1389.73 1.00 1980 68 386 2 FALSE 1.99
non-small cell lung cancer KRAS_G12C KMT2D 445 318 Age:overall -0.13 -0.69 0.40 1195.60 1.00 2763 408 281 37 FALSE 0.20
colorectal cancer KRAS_G12C TSC2 6 14 <40yrs -5.44 -13.82 -0.84 303.33 1.01 199 6 14 0 TRUE 1.00
colorectal cancer KRAS_G12C TSC2 10 19 40-50yrs -5.43 -13.80 -0.80 308.88 1.01 423 10 19 0 TRUE 1.00
colorectal cancer KRAS_G12C TSC2 31 36 50-65yrs -5.44 -13.79 -0.92 310.23 1.01 906 31 36 0 TRUE 1.00
colorectal cancer KRAS_G12C TSC2 23 46 >65yrs -5.44 -13.75 -0.90 308.66 1.01 591 23 46 0 TRUE 1.00
non-small cell lung cancer KRAS_G12C TSC2 152 23 50-65yrs -0.87 -2.25 0.23 1508.59 1.00 1144 150 21 2 TRUE 0.79
non-small cell lung cancer KRAS_G12C TSC2 291 44 >65yrs -1.02 -2.38 0.03 1439.46 1.00 1797 289 42 2 TRUE 1.08
colorectal cancer KRAS_G12C TSC2 70 115 Age:overall -5.43 -13.81 -0.95 298.37 1.01 2119 70 115 0 TRUE 1.01
non-small cell lung cancer KRAS_G12C TSC2 443 67 Age:overall -0.95 -2.39 0.32 1603.99 1.00 2941 439 63 4 TRUE 0.79
colorectal cancer KRAS_G12C APC 7 246 <40yrs 0.01 -0.59 0.57 846.35 1.00 85 4 243 3 TRUE 0.01
colorectal cancer KRAS_G12C APC 14 494 40-50yrs 0.10 -0.41 0.70 896.59 1.00 169 0 480 14 TRUE 0.15
colorectal cancer KRAS_G12C APC 51 1094 50-65yrs 0.06 -0.46 0.54 782.12 1.00 354 16 1059 35 TRUE 0.08
colorectal cancer KRAS_G12C APC 35 704 >65yrs 0.14 -0.34 0.67 843.93 1.00 257 6 675 29 TRUE 0.25
non-small cell lung cancer KRAS_G12C APC 159 60 50-65yrs -0.71 -2.00 0.12 1185.52 1.00 1160 157 58 2 TRUE 0.70
non-small cell lung cancer KRAS_G12C APC 303 87 >65yrs -0.14 -0.80 0.48 1342.58 1.00 1811 290 74 13 TRUE 0.18
colorectal cancer KRAS_G12C APC 107 2538 Age:overall 0.08 -0.42 0.58 865.16 1.00 865 26 2457 81 TRUE 0.13
non-small cell lung cancer KRAS_G12C APC 462 147 Age:overall -0.42 -1.72 0.56 1453.16 1.00 2971 447 132 15 TRUE 0.32
colorectal cancer KRAS_G12C ERBB2 7 13 <40yrs 0.29 -0.94 1.28 1107.06 1.00 216 7 13 0 TRUE 0.22
colorectal cancer KRAS_G12C ERBB2 10 13 40-50yrs 0.36 -0.81 1.38 1091.54 1.00 463 9 12 1 TRUE 0.27
colorectal cancer KRAS_G12C ERBB2 39 49 50-65yrs 0.36 -0.74 1.27 1165.83 1.00 995 36 46 3 TRUE 0.32
colorectal cancer KRAS_G12C ERBB2 25 29 >65yrs 0.30 -0.89 1.30 1136.89 1.00 670 24 28 1 TRUE 0.23
non-small cell lung cancer KRAS_G12C ERBB2 159 53 50-65yrs -3.20 -5.62 -1.19 909.47 1.00 1164 158 52 1 TRUE 2.25
non-small cell lung cancer KRAS_G12C ERBB2 300 68 >65yrs -3.47 -6.49 -1.42 754.96 1.00 1818 300 68 0 TRUE 2.08
colorectal cancer KRAS_G12C ERBB2 81 104 Age:overall 0.33 -0.75 1.27 1096.43 1.00 2344 76 99 5 TRUE 0.28
non-small cell lung cancer KRAS_G12C ERBB2 459 121 Age:overall -3.32 -5.93 -1.36 980.08 1.00 2982 458 120 1 TRUE 2.29
colorectal cancer KRAS_G12C JAK1 6 16 <40yrs -5.23 -11.04 -0.52 45.79 1.08 202 6 16 0 TRUE 1.03
colorectal cancer KRAS_G12C JAK1 10 13 40-50yrs -5.20 -11.05 -0.44 44.65 1.08 430 10 13 0 TRUE 1.02
colorectal cancer KRAS_G12C JAK1 31 20 50-65yrs -5.24 -11.06 -0.62 46.03 1.08 918 31 20 0 TRUE 1.05
colorectal cancer KRAS_G12C JAK1 23 26 >65yrs -5.24 -11.04 -0.60 46.04 1.09 603 23 26 0 TRUE 1.05
non-small cell lung cancer KRAS_G12C JAK1 152 15 50-65yrs -0.46 -1.86 0.64 1320.19 1.00 1149 151 14 1 TRUE 0.34
non-small cell lung cancer KRAS_G12C JAK1 291 34 >65yrs -0.35 -1.39 0.56 1068.85 1.00 1810 287 30 4 TRUE 0.32
colorectal cancer KRAS_G12C JAK1 70 75 Age:overall -5.22 -11.06 -0.55 44.84 1.09 2153 70 75 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C JAK1 443 49 Age:overall -0.39 -1.64 0.69 1236.26 1.00 2959 438 44 5 TRUE 0.29
colorectal cancer KRAS_G12C ARID2 10 21 40-50yrs -1.77 -4.70 0.16 1503.22 1.00 422 10 21 0 FALSE 0.81
colorectal cancer KRAS_G12C ARID2 31 36 50-65yrs -1.63 -4.34 0.24 1434.27 1.00 907 30 35 1 FALSE 0.75
colorectal cancer KRAS_G12C ARID2 23 44 >65yrs -1.80 -4.70 0.10 1301.62 1.00 586 23 44 0 FALSE 0.85
non-small cell lung cancer KRAS_G12C ARID2 152 71 50-65yrs 0.28 -0.27 0.87 598.61 1.00 1108 139 58 13 FALSE 0.47
non-small cell lung cancer KRAS_G12C ARID2 292 105 >65yrs 0.05 -0.50 0.52 1027.46 1.00 1755 279 92 13 FALSE 0.07
colorectal cancer KRAS_G12C ARID2 64 101 Age:overall -1.72 -4.52 0.16 1323.62 1.00 1915 63 100 1 FALSE 0.83
non-small cell lung cancer KRAS_G12C ARID2 444 176 Age:overall 0.16 -0.54 0.86 1373.38 1.00 2863 418 150 26 FALSE 0.17
colorectal cancer KRAS_G12C SOX17 10 11 40-50yrs -0.46 -2.93 1.36 1498.22 1.00 415 10 11 0 FALSE 0.16
colorectal cancer KRAS_G12C SOX17 29 32 50-65yrs -0.64 -3.29 0.98 1543.77 1.00 880 29 32 0 FALSE 0.25
colorectal cancer KRAS_G12C SOX17 22 47 >65yrs 0.09 -1.53 1.39 1398.45 1.00 572 19 44 3 FALSE 0.05
non-small cell lung cancer KRAS_G12C SOX17 152 26 50-65yrs 1.04 0.16 1.96 1101.09 1.00 1141 143 17 9 FALSE 1.64
non-small cell lung cancer KRAS_G12C SOX17 291 32 >65yrs 0.25 -0.88 1.10 1389.90 1.00 1803 287 28 4 FALSE 0.21
colorectal cancer KRAS_G12C SOX17 61 90 Age:overall -0.34 -2.49 1.22 1502.71 1.00 1867 58 87 3 FALSE 0.14
non-small cell lung cancer KRAS_G12C SOX17 443 58 Age:overall 0.64 -0.69 1.87 1356.44 1.00 2944 430 45 13 FALSE 0.51
colorectal cancer KRAS_G12C MTOR 6 15 <40yrs -0.21 -1.33 0.79 87.30 1.03 200 6 15 0 TRUE 0.14
colorectal cancer KRAS_G12C MTOR 10 26 40-50yrs -0.20 -1.28 0.77 85.46 1.03 420 9 25 1 TRUE 0.14
colorectal cancer KRAS_G12C MTOR 31 54 50-65yrs -0.22 -1.32 0.74 79.21 1.04 890 30 53 1 TRUE 0.16
colorectal cancer KRAS_G12C MTOR 23 45 >65yrs -0.18 -1.30 0.77 78.06 1.04 589 21 43 2 TRUE 0.13
non-small cell lung cancer KRAS_G12C MTOR 153 39 50-65yrs 0.60 0.02 1.17 806.80 1.00 1132 145 31 8 TRUE 1.37
non-small cell lung cancer KRAS_G12C MTOR 292 70 >65yrs 0.58 0.07 1.08 968.65 1.00 1783 277 55 15 TRUE 1.57
colorectal cancer KRAS_G12C MTOR 70 140 Age:overall -0.20 -1.29 0.74 77.66 1.04 2099 66 136 4 TRUE 0.14
non-small cell lung cancer KRAS_G12C MTOR 445 109 Age:overall 0.59 -0.04 1.19 1245.40 1.00 2915 422 86 23 TRUE 1.11
non-small cell lung cancer KRAS_G12C RFWD2 152 25 50-65yrs 0.65 -0.10 1.40 1481.35 1.00 1138 146 19 6 FALSE 1.07
non-small cell lung cancer KRAS_G12C RFWD2 291 31 >65yrs 0.52 -0.23 1.16 1415.75 1.00 1805 285 25 6 FALSE 0.84
non-small cell lung cancer KRAS_G12C RFWD2 443 56 Age:overall 0.59 -0.28 1.47 1541.48 1.00 2943 431 44 12 FALSE 0.73
colorectal cancer KRAS_G12C IRS1 10 17 40-50yrs -1.50 -4.02 0.36 1444.28 1.00 412 10 17 0 FALSE 0.73
colorectal cancer KRAS_G12C IRS1 29 34 50-65yrs -1.40 -3.98 0.37 1404.06 1.00 883 28 33 1 FALSE 0.69
colorectal cancer KRAS_G12C IRS1 22 36 >65yrs -1.53 -4.13 0.36 1311.34 1.00 578 22 36 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C IRS1 152 28 50-65yrs -0.41 -1.38 0.49 236.34 1.01 1131 150 26 2 FALSE 0.38
non-small cell lung cancer KRAS_G12C IRS1 291 42 >65yrs -0.35 -1.30 0.48 192.94 1.01 1796 286 37 5 FALSE 0.35
colorectal cancer KRAS_G12C IRS1 61 87 Age:overall -1.48 -4.02 0.33 1399.37 1.00 1873 60 86 1 FALSE 0.74
non-small cell lung cancer KRAS_G12C IRS1 443 70 Age:overall -0.38 -1.38 0.50 330.30 1.01 2927 436 63 7 FALSE 0.33
colorectal cancer KRAS_G12C NOTCH1 7 18 <40yrs -5.31 -11.94 -1.40 1239.56 1.00 216 7 18 0 TRUE 1.25
colorectal cancer KRAS_G12C NOTCH1 10 27 40-50yrs -5.32 -12.13 -1.31 1254.02 1.00 455 10 27 0 TRUE 1.25
colorectal cancer KRAS_G12C NOTCH1 39 55 50-65yrs -5.33 -11.86 -1.40 1178.34 1.00 991 39 55 0 TRUE 1.25
colorectal cancer KRAS_G12C NOTCH1 25 72 >65yrs -5.33 -11.93 -1.45 1195.91 1.00 642 25 72 0 TRUE 1.26
non-small cell lung cancer KRAS_G12C NOTCH1 160 45 50-65yrs -0.18 -0.94 0.56 1245.97 1.00 1175 154 39 6 TRUE 0.20
non-small cell lung cancer KRAS_G12C NOTCH1 300 77 >65yrs -0.32 -1.02 0.30 1366.69 1.00 1817 293 70 7 TRUE 0.48
colorectal cancer KRAS_G12C NOTCH1 81 172 Age:overall -5.32 -11.94 -1.44 1216.71 1.00 2304 81 172 0 TRUE 1.26
non-small cell lung cancer KRAS_G12C NOTCH1 460 122 Age:overall -0.26 -1.04 0.52 1391.23 1.00 2992 447 109 13 TRUE 0.28
colorectal cancer KRAS_G12C NTRK1 6 12 <40yrs -4.82 -11.57 -0.23 235.66 1.01 201 6 12 0 TRUE 0.96
colorectal cancer KRAS_G12C NTRK1 31 19 50-65yrs -4.81 -11.67 -0.28 224.01 1.01 917 31 19 0 TRUE 0.96
colorectal cancer KRAS_G12C NTRK1 23 26 >65yrs -4.81 -11.60 -0.33 218.26 1.01 602 23 26 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C NTRK1 152 35 50-65yrs 0.66 -0.06 1.32 1334.66 1.00 1138 144 27 8 TRUE 1.24
non-small cell lung cancer KRAS_G12C NTRK1 291 46 >65yrs 0.53 -0.12 1.10 1343.33 1.00 1800 282 37 9 TRUE 1.05
colorectal cancer KRAS_G12C NTRK1 60 57 Age:overall -4.79 -11.59 -0.35 219.09 1.01 1720 60 57 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C NTRK1 443 81 Age:overall 0.60 -0.21 1.36 1140.28 1.00 2938 426 64 17 TRUE 0.78
non-small cell lung cancer KRAS_G12C INPP4A 152 21 50-65yrs 0.38 -0.46 1.21 460.67 1.01 1140 148 17 4 FALSE 0.43
non-small cell lung cancer KRAS_G12C INPP4A 291 29 >65yrs 0.31 -0.55 1.04 357.41 1.02 1806 286 24 5 FALSE 0.36
non-small cell lung cancer KRAS_G12C INPP4A 443 50 Age:overall 0.33 -0.69 1.19 641.78 1.01 2946 434 41 9 FALSE 0.32
colorectal cancer KRAS_G12C CASP8 10 11 40-50yrs -5.02 -12.43 -0.49 631.46 1.01 416 10 11 0 FALSE 1.02
colorectal cancer KRAS_G12C CASP8 29 30 50-65yrs -5.00 -12.51 -0.67 668.70 1.00 885 29 30 0 FALSE 1.03
colorectal cancer KRAS_G12C CASP8 22 46 >65yrs -5.01 -12.53 -0.60 703.96 1.00 572 22 46 0 FALSE 1.03
colorectal cancer KRAS_G12C CASP8 61 87 Age:overall -4.98 -12.47 -0.68 638.29 1.01 1873 61 87 0 FALSE 1.04
colorectal cancer KRAS_G12C SETD2 6 20 <40yrs -5.21 -11.60 -1.10 1069.35 1.01 196 6 20 0 FALSE 1.15
colorectal cancer KRAS_G12C SETD2 10 15 40-50yrs -5.23 -11.98 -1.04 1048.33 1.01 428 10 15 0 FALSE 1.14
colorectal cancer KRAS_G12C SETD2 31 49 50-65yrs -5.22 -11.70 -1.20 1053.61 1.00 897 31 49 0 FALSE 1.15
colorectal cancer KRAS_G12C SETD2 23 29 >65yrs -5.24 -11.73 -1.04 1058.48 1.01 601 23 29 0 FALSE 1.14
non-small cell lung cancer KRAS_G12C SETD2 154 82 50-65yrs 0.22 -0.23 0.71 881.10 1.00 1103 142 70 12 FALSE 0.43
non-small cell lung cancer KRAS_G12C SETD2 294 132 >65yrs 0.20 -0.22 0.63 873.59 1.00 1745 273 111 21 FALSE 0.46
colorectal cancer KRAS_G12C SETD2 70 113 Age:overall -5.21 -11.73 -1.08 1058.83 1.01 2122 70 113 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C SETD2 448 214 Age:overall 0.20 -0.34 0.70 1097.04 1.00 2848 415 181 33 FALSE 0.32
colorectal cancer KRAS_G12C PBRM1 10 21 40-50yrs -3.69 -10.76 -0.91 4.14 1.25 422 10 21 0 TRUE 0.73
colorectal cancer KRAS_G12C PBRM1 31 32 50-65yrs -3.69 -10.83 -0.89 4.18 1.25 910 31 32 0 TRUE 0.73
colorectal cancer KRAS_G12C PBRM1 23 31 >65yrs -3.69 -10.78 -0.94 4.18 1.25 597 23 31 0 TRUE 0.73
non-small cell lung cancer KRAS_G12C PBRM1 152 37 50-65yrs -0.05 -0.86 0.60 1436.89 1.00 1136 148 33 4 TRUE 0.05
non-small cell lung cancer KRAS_G12C PBRM1 291 71 >65yrs -0.01 -0.63 0.57 1196.51 1.00 1784 281 61 10 TRUE 0.01
colorectal cancer KRAS_G12C PBRM1 64 84 Age:overall -3.69 -10.75 -0.88 4.17 1.25 1929 64 84 0 TRUE 0.73
non-small cell lung cancer KRAS_G12C PBRM1 443 108 Age:overall -0.02 -0.84 0.65 1499.74 1.00 2920 429 94 14 TRUE 0.02
colorectal cancer KRAS_G12C EPHA3 6 14 <40yrs -0.86 -2.81 0.53 1419.52 1.00 200 6 14 0 FALSE 0.51
colorectal cancer KRAS_G12C EPHA3 10 15 40-50yrs -0.85 -2.71 0.53 1365.12 1.00 428 10 15 0 FALSE 0.51
colorectal cancer KRAS_G12C EPHA3 31 39 50-65yrs -0.81 -2.70 0.53 1340.20 1.00 899 30 38 1 FALSE 0.50
colorectal cancer KRAS_G12C EPHA3 23 45 >65yrs -0.83 -2.76 0.51 1380.17 1.00 587 22 44 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C EPHA3 11 11 40-50yrs 0.76 -0.09 2.10 1380.50 1.00 174 8 8 3 FALSE 0.82
non-small cell lung cancer KRAS_G12C EPHA3 156 103 50-65yrs 0.51 0.02 0.98 1446.20 1.00 1086 138 85 18 FALSE 1.44
non-small cell lung cancer KRAS_G12C EPHA3 293 126 >65yrs 0.37 -0.10 0.77 1339.07 1.00 1738 271 104 22 FALSE 0.99
colorectal cancer KRAS_G12C EPHA3 70 113 Age:overall -0.84 -2.73 0.46 1378.16 1.00 2114 68 111 2 FALSE 0.54
non-small cell lung cancer KRAS_G12C EPHA3 460 240 Age:overall 0.56 -0.10 1.43 1566.94 1.00 2998 417 197 43 FALSE 0.88
colorectal cancer KRAS_G12C KIT 10 13 40-50yrs 0.51 -1.07 1.84 1520.20 1.00 464 9 12 1 TRUE 0.32
colorectal cancer KRAS_G12C KIT 39 20 50-65yrs 0.54 -0.92 1.71 1408.55 1.00 1019 37 18 2 TRUE 0.38
colorectal cancer KRAS_G12C KIT 25 17 >65yrs 0.38 -1.39 1.60 1417.71 1.00 680 25 17 0 TRUE 0.21
non-small cell lung cancer KRAS_G12C KIT 159 25 50-65yrs 0.68 -0.01 1.37 1261.36 1.00 1195 153 19 6 TRUE 1.27
non-small cell lung cancer KRAS_G12C KIT 300 52 >65yrs 0.60 -0.01 1.18 1318.63 1.00 1845 289 41 11 TRUE 1.33
colorectal cancer KRAS_G12C KIT 74 50 Age:overall 0.48 -0.99 1.66 1471.30 1.00 2163 71 47 3 TRUE 0.31
non-small cell lung cancer KRAS_G12C KIT 459 77 Age:overall 0.63 -0.18 1.41 1496.11 1.00 3040 442 60 17 TRUE 0.86
colorectal cancer KRAS_G12C KDR 7 11 <40yrs -0.60 -2.81 1.07 80.87 1.04 221 7 11 0 TRUE 0.26
colorectal cancer KRAS_G12C KDR 39 29 50-65yrs -0.66 -2.76 0.88 93.55 1.04 1008 39 29 0 TRUE 0.30
colorectal cancer KRAS_G12C KDR 25 26 >65yrs -0.46 -2.59 1.10 56.62 1.06 678 23 24 2 TRUE 0.20
non-small cell lung cancer KRAS_G12C KDR 160 58 50-65yrs 0.08 -0.49 0.63 1414.06 1.00 1167 153 51 7 TRUE 0.11
non-small cell lung cancer KRAS_G12C KDR 300 88 >65yrs 0.12 -0.37 0.63 1494.63 1.00 1811 286 74 14 TRUE 0.20
colorectal cancer KRAS_G12C KDR 71 66 Age:overall -0.57 -2.67 0.98 67.15 1.05 1907 69 64 2 TRUE 0.27
non-small cell lung cancer KRAS_G12C KDR 460 146 Age:overall 0.10 -0.54 0.70 1420.96 1.00 2978 439 125 21 TRUE 0.12
colorectal cancer KRAS_G12C RICTOR 10 13 40-50yrs -0.34 -2.32 1.12 586.43 1.00 431 10 13 0 FALSE 0.16
colorectal cancer KRAS_G12C RICTOR 31 24 50-65yrs -0.29 -2.22 1.11 723.49 1.01 915 30 23 1 FALSE 0.14
colorectal cancer KRAS_G12C RICTOR 23 25 >65yrs -0.29 -2.21 1.16 848.11 1.00 606 22 24 1 FALSE 0.14
non-small cell lung cancer KRAS_G12C RICTOR 152 24 50-65yrs -0.53 -1.94 0.44 1279.08 1.00 1140 151 23 1 FALSE 0.43
non-small cell lung cancer KRAS_G12C RICTOR 291 37 >65yrs -0.31 -1.27 0.57 1163.14 1.00 1807 286 32 5 FALSE 0.29
colorectal cancer KRAS_G12C RICTOR 64 62 Age:overall -0.30 -2.20 1.10 651.79 1.00 1952 62 60 2 FALSE 0.14
non-small cell lung cancer KRAS_G12C RICTOR 443 61 Age:overall -0.42 -1.67 0.67 1505.63 1.00 2947 437 55 6 FALSE 0.31
colorectal cancer KRAS_G12C RAD50 10 13 40-50yrs -0.90 -3.88 0.86 61.90 1.05 429 10 13 0 FALSE 0.33
colorectal cancer KRAS_G12C RAD50 31 22 50-65yrs -0.92 -3.86 0.75 57.19 1.06 916 31 22 0 FALSE 0.34
colorectal cancer KRAS_G12C RAD50 23 20 >65yrs -0.85 -3.72 0.84 61.66 1.05 610 22 19 1 FALSE 0.32
colorectal cancer KRAS_G12C RAD50 64 55 Age:overall -0.88 -3.69 0.83 59.16 1.05 1955 63 54 1 FALSE 0.33
colorectal cancer KRAS_G12C CSF1R 10 15 40-50yrs -4.20 -10.84 0.23 81.89 1.01 463 10 15 0 TRUE 0.83
colorectal cancer KRAS_G12C CSF1R 39 21 50-65yrs -4.18 -10.67 0.23 79.72 1.01 1017 39 21 0 TRUE 0.82
colorectal cancer KRAS_G12C CSF1R 25 15 >65yrs -4.20 -10.88 0.22 81.96 1.01 682 25 15 0 TRUE 0.82
non-small cell lung cancer KRAS_G12C CSF1R 159 22 50-65yrs -0.12 -1.95 0.85 1076.23 1.00 1195 158 21 1 TRUE 0.06
non-small cell lung cancer KRAS_G12C CSF1R 300 45 >65yrs 0.48 -0.24 1.18 853.49 1.00 1850 289 34 11 TRUE 0.74
colorectal cancer KRAS_G12C CSF1R 74 51 Age:overall -4.18 -10.76 0.20 80.49 1.01 2162 74 51 0 TRUE 0.83
non-small cell lung cancer KRAS_G12C CSF1R 459 67 Age:overall 0.18 -1.37 1.17 1317.32 1.00 3045 447 55 12 TRUE 0.11
non-small cell lung cancer KRAS_G12C PARK2 152 27 50-65yrs 0.30 -0.55 1.09 1344.28 1.00 1141 147 22 5 FALSE 0.33
non-small cell lung cancer KRAS_G12C PARK2 291 36 >65yrs 0.16 -0.68 0.88 1211.80 1.00 1806 286 31 5 FALSE 0.16
non-small cell lung cancer KRAS_G12C PARK2 443 63 Age:overall 0.22 -0.70 1.12 1337.08 1.00 2947 433 53 10 FALSE 0.19
non-small cell lung cancer KRAS_G12C NTRK2 153 24 50-65yrs 0.55 -0.28 1.31 1368.74 1.00 1145 147 18 6 FALSE 0.75
non-small cell lung cancer KRAS_G12C NTRK2 291 39 >65yrs 0.35 -0.46 1.03 1236.06 1.00 1808 285 33 6 FALSE 0.44
non-small cell lung cancer KRAS_G12C NTRK2 444 63 Age:overall 0.45 -0.44 1.27 1410.39 1.00 2953 432 51 12 FALSE 0.51
colorectal cancer KRAS_G12C PTCH1 6 16 <40yrs -2.03 -4.76 -0.04 1006.54 1.00 200 6 16 0 TRUE 0.99
colorectal cancer KRAS_G12C PTCH1 10 21 40-50yrs -2.03 -4.88 -0.08 934.60 1.00 422 10 21 0 TRUE 1.01
colorectal cancer KRAS_G12C PTCH1 31 53 50-65yrs -2.05 -4.90 -0.08 911.49 1.00 900 31 53 0 TRUE 1.02
colorectal cancer KRAS_G12C PTCH1 23 55 >65yrs -1.96 -4.72 -0.04 957.53 1.00 581 22 54 1 TRUE 0.98
non-small cell lung cancer KRAS_G12C PTCH1 152 21 50-65yrs 0.48 -0.33 1.23 1049.21 1.00 1146 148 17 4 TRUE 0.64
non-small cell lung cancer KRAS_G12C PTCH1 291 35 >65yrs 0.46 -0.30 1.11 1073.95 1.00 1809 284 28 7 TRUE 0.69
colorectal cancer KRAS_G12C PTCH1 70 145 Age:overall -2.01 -4.84 -0.15 951.30 1.00 2103 69 144 1 TRUE 1.03
non-small cell lung cancer KRAS_G12C PTCH1 443 56 Age:overall 0.46 -0.44 1.24 1127.03 1.00 2955 432 45 11 TRUE 0.51
colorectal cancer KRAS_G12C TET1 10 23 40-50yrs -1.66 -4.51 0.19 1322.19 1.00 412 10 23 0 FALSE 0.75
colorectal cancer KRAS_G12C TET1 29 27 50-65yrs -1.67 -4.48 0.21 1204.04 1.00 887 29 27 0 FALSE 0.77
colorectal cancer KRAS_G12C TET1 22 37 >65yrs -1.55 -4.35 0.31 1106.24 1.00 581 21 36 1 FALSE 0.71
non-small cell lung cancer KRAS_G12C TET1 153 35 50-65yrs -0.32 -1.22 0.43 1359.10 1.00 1128 150 32 3 FALSE 0.36
non-small cell lung cancer KRAS_G12C TET1 291 82 >65yrs -0.22 -0.88 0.41 977.66 1.00 1766 281 72 10 FALSE 0.31
colorectal cancer KRAS_G12C TET1 66 103 Age:overall -1.63 -4.42 0.23 1189.43 1.00 2076 65 102 1 FALSE 0.78
non-small cell lung cancer KRAS_G12C TET1 444 117 Age:overall -0.26 -1.17 0.61 1368.40 1.00 2894 431 104 13 FALSE 0.24
colorectal cancer KRAS_G12C FGFR2 10 14 40-50yrs -4.71 -10.99 -0.25 399.65 1.01 462 10 14 0 TRUE 1.03
colorectal cancer KRAS_G12C FGFR2 39 15 50-65yrs -4.75 -11.06 -0.38 351.52 1.02 1020 39 15 0 TRUE 1.05
colorectal cancer KRAS_G12C FGFR2 25 17 >65yrs -4.74 -11.22 -0.36 368.70 1.02 680 25 17 0 TRUE 1.04
colorectal cancer KRAS_G12C FGFR2 74 46 Age:overall -4.71 -11.04 -0.32 348.63 1.02 2162 74 46 0 TRUE 1.05
colorectal cancer KRAS_G12C TBX3 10 13 40-50yrs -4.83 -11.49 -0.56 649.70 1.01 430 10 13 0 FALSE 1.02
colorectal cancer KRAS_G12C TBX3 31 30 50-65yrs -4.83 -11.55 -0.58 745.57 1.01 909 31 30 0 FALSE 1.02
colorectal cancer KRAS_G12C TBX3 23 30 >65yrs -4.84 -11.61 -0.58 718.01 1.01 602 23 30 0 FALSE 1.03
non-small cell lung cancer KRAS_G12C TBX3 152 58 50-65yrs 0.49 -0.06 1.05 1344.31 1.00 1123 141 47 11 FALSE 1.10
non-small cell lung cancer KRAS_G12C TBX3 291 74 >65yrs 0.38 -0.16 0.88 1347.26 1.00 1778 278 61 13 FALSE 0.80
colorectal cancer KRAS_G12C TBX3 64 73 Age:overall -4.82 -11.57 -0.57 702.50 1.01 1941 64 73 0 FALSE 1.03
non-small cell lung cancer KRAS_G12C TBX3 443 132 Age:overall 0.43 -0.26 1.10 1560.79 1.00 2901 419 108 24 FALSE 0.63
colorectal cancer KRAS_G12C HNF1A 39 25 50-65yrs -4.82 -11.65 -0.18 154.53 1.01 1012 39 25 0 TRUE 0.89
colorectal cancer KRAS_G12C HNF1A 25 19 >65yrs -4.85 -11.74 -0.18 163.89 1.01 677 25 19 0 TRUE 0.88
colorectal cancer KRAS_G12C HNF1A 64 44 Age:overall -4.80 -11.67 -0.22 155.72 1.01 1689 64 44 0 TRUE 0.89
colorectal cancer KRAS_G12C DICER1 6 11 <40yrs -4.70 -12.09 -0.42 1120.89 1.00 204 6 11 0 TRUE 0.96
colorectal cancer KRAS_G12C DICER1 10 19 40-50yrs -4.69 -12.25 -0.47 1150.31 1.00 425 10 19 0 TRUE 0.96
colorectal cancer KRAS_G12C DICER1 31 23 50-65yrs -4.71 -11.97 -0.49 1129.24 1.00 917 31 23 0 TRUE 0.97
colorectal cancer KRAS_G12C DICER1 23 23 >65yrs -4.70 -12.04 -0.47 1128.55 1.00 606 23 23 0 TRUE 0.97
non-small cell lung cancer KRAS_G12C DICER1 152 26 50-65yrs 0.28 -0.53 1.03 594.62 1.01 1142 147 21 5 TRUE 0.32
non-small cell lung cancer KRAS_G12C DICER1 291 59 >65yrs 0.14 -0.56 0.69 318.94 1.01 1791 283 51 8 TRUE 0.17
colorectal cancer KRAS_G12C DICER1 70 76 Age:overall -4.70 -12.10 -0.48 1136.05 1.00 2152 70 76 0 TRUE 0.97
non-small cell lung cancer KRAS_G12C DICER1 443 85 Age:overall 0.20 -0.66 1.00 622.60 1.00 2933 430 72 13 TRUE 0.19
colorectal cancer KRAS_G12C SMAD3 10 33 40-50yrs -1.51 -4.50 0.54 1177.72 1.00 416 9 32 1 TRUE 0.64
colorectal cancer KRAS_G12C SMAD3 31 44 50-65yrs -1.75 -4.74 0.21 1208.29 1.00 898 31 44 0 TRUE 0.81
colorectal cancer KRAS_G12C SMAD3 23 23 >65yrs -1.71 -4.78 0.22 1192.98 1.00 604 23 23 0 TRUE 0.74
colorectal cancer KRAS_G12C SMAD3 64 100 Age:overall -1.66 -4.59 0.22 1154.28 1.00 1918 63 99 1 TRUE 0.76
colorectal cancer KRAS_G12C NTRK3 6 11 <40yrs -1.32 -4.19 0.61 939.01 1.00 201 6 11 0 FALSE 0.56
colorectal cancer KRAS_G12C NTRK3 10 16 40-50yrs -1.23 -4.01 0.78 940.91 1.00 430 9 15 1 FALSE 0.52
colorectal cancer KRAS_G12C NTRK3 31 21 50-65yrs -1.34 -4.00 0.55 930.01 1.00 916 31 21 0 FALSE 0.58
colorectal cancer KRAS_G12C NTRK3 23 22 >65yrs -1.32 -4.11 0.60 871.22 1.00 606 23 22 0 FALSE 0.57
non-small cell lung cancer KRAS_G12C NTRK3 152 64 50-65yrs 0.91 0.44 1.37 1269.25 1.00 1121 136 48 16 FALSE 4.07
non-small cell lung cancer KRAS_G12C NTRK3 295 134 >65yrs 0.86 0.47 1.21 1413.42 1.00 1751 261 100 34 FALSE 5.16
colorectal cancer KRAS_G12C NTRK3 70 70 Age:overall -1.30 -4.00 0.64 915.97 1.00 2153 69 69 1 FALSE 0.57
non-small cell lung cancer KRAS_G12C NTRK3 447 198 Age:overall 0.89 0.30 1.46 1444.35 1.00 2872 397 148 50 FALSE 2.51
colorectal cancer KRAS_G12C AXIN1 31 22 50-65yrs -5.16 -11.87 -0.39 767.61 1.01 917 31 22 0 FALSE 1.01
colorectal cancer KRAS_G12C AXIN1 23 37 >65yrs -5.18 -11.89 -0.52 676.19 1.01 594 23 37 0 FALSE 1.03
colorectal cancer KRAS_G12C AXIN1 54 59 Age:overall -5.06 -11.67 -0.32 684.02 1.01 1511 54 59 0 FALSE 1.01
colorectal cancer KRAS_G12C GRIN2A 6 15 <40yrs -0.18 -1.49 0.81 325.65 1.01 198 6 15 0 FALSE 0.12
colorectal cancer KRAS_G12C GRIN2A 10 29 40-50yrs -0.19 -1.50 0.85 315.07 1.01 418 10 29 0 FALSE 0.13
colorectal cancer KRAS_G12C GRIN2A 31 50 50-65yrs -0.13 -1.46 0.90 327.87 1.01 890 28 47 3 FALSE 0.09
colorectal cancer KRAS_G12C GRIN2A 23 42 >65yrs -0.17 -1.48 0.85 324.05 1.01 590 22 41 1 FALSE 0.12
non-small cell lung cancer KRAS_G12C GRIN2A 11 11 40-50yrs 0.18 -0.77 1.14 1542.82 1.00 171 10 10 1 FALSE 0.15
non-small cell lung cancer KRAS_G12C GRIN2A 154 70 50-65yrs 0.35 -0.20 0.96 753.46 1.00 1109 141 57 13 FALSE 0.62
non-small cell lung cancer KRAS_G12C GRIN2A 292 110 >65yrs -0.02 -0.56 0.43 1408.34 1.00 1745 279 97 13 FALSE 0.04
colorectal cancer KRAS_G12C GRIN2A 70 136 Age:overall -0.16 -1.45 0.82 308.86 1.01 2096 66 132 4 FALSE 0.12
non-small cell lung cancer KRAS_G12C GRIN2A 457 191 Age:overall 0.16 -0.54 0.83 1315.86 1.00 3025 430 164 27 FALSE 0.19
colorectal cancer KRAS_G12C PALB2 6 13 <40yrs -4.61 -10.98 -0.17 1104.84 1.00 200 6 13 0 TRUE 0.93
colorectal cancer KRAS_G12C PALB2 31 18 50-65yrs -4.64 -11.14 -0.30 996.84 1.00 919 31 18 0 TRUE 0.94
colorectal cancer KRAS_G12C PALB2 23 20 >65yrs -4.68 -11.24 -0.37 1019.72 1.00 608 23 20 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C PALB2 152 30 50-65yrs 0.41 -0.39 1.21 1287.94 1.00 1141 147 25 5 TRUE 0.50
non-small cell lung cancer KRAS_G12C PALB2 291 29 >65yrs 0.40 -0.43 1.12 1328.68 1.00 1814 285 23 6 TRUE 0.50
colorectal cancer KRAS_G12C PALB2 60 51 Age:overall -4.63 -11.10 -0.34 1099.90 1.00 1727 60 51 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C PALB2 443 59 Age:overall 0.42 -0.59 1.39 1400.32 1.00 2955 432 48 11 TRUE 0.38
colorectal cancer KRAS_G12C CTCF 10 20 40-50yrs -0.59 -2.62 0.90 978.08 1.00 424 10 20 0 FALSE 0.28
colorectal cancer KRAS_G12C CTCF 31 30 50-65yrs -0.64 -2.59 0.84 967.33 1.00 909 31 30 0 FALSE 0.31
colorectal cancer KRAS_G12C CTCF 23 32 >65yrs -0.42 -2.36 1.00 1091.70 1.00 601 21 30 2 FALSE 0.20
colorectal cancer KRAS_G12C CTCF 64 82 Age:overall -0.54 -2.45 0.93 1038.75 1.00 1934 62 80 2 FALSE 0.27
colorectal cancer KRAS_G12C CDH1 39 22 50-65yrs -4.75 -11.60 -0.35 23.52 1.09 1016 39 22 0 TRUE 0.86
colorectal cancer KRAS_G12C CDH1 25 18 >65yrs -4.72 -11.63 -0.30 25.27 1.08 682 25 18 0 TRUE 0.85
colorectal cancer KRAS_G12C CDH1 64 40 Age:overall -4.69 -11.55 -0.27 26.54 1.08 1698 64 40 0 TRUE 0.85
colorectal cancer KRAS_G12C CDK12 10 13 40-50yrs -0.53 -2.37 0.88 674.09 1.00 428 10 13 0 FALSE 0.28
colorectal cancer KRAS_G12C CDK12 31 39 50-65yrs -0.58 -2.41 0.76 631.54 1.00 902 31 39 0 FALSE 0.30
colorectal cancer KRAS_G12C CDK12 24 28 >65yrs -0.36 -2.08 1.01 627.05 1.00 606 22 26 2 FALSE 0.19
non-small cell lung cancer KRAS_G12C CDK12 152 15 50-65yrs -0.65 -2.18 0.49 1384.55 1.00 1149 151 14 1 FALSE 0.48
non-small cell lung cancer KRAS_G12C CDK12 291 42 >65yrs -0.53 -1.56 0.36 1515.14 1.00 1801 287 38 4 FALSE 0.54
colorectal cancer KRAS_G12C CDK12 65 80 Age:overall -0.50 -2.22 0.82 683.26 1.00 1936 63 78 2 FALSE 0.27
non-small cell lung cancer KRAS_G12C CDK12 443 57 Age:overall -0.60 -2.12 0.62 1517.30 1.00 2950 438 52 5 FALSE 0.43
non-small cell lung cancer KRAS_G12C STK11 11 19 40-50yrs 0.94 0.21 1.73 1580.16 1.00 174 8 16 3 TRUE 2.02
non-small cell lung cancer KRAS_G12C STK11 161 196 50-65yrs 0.94 0.60 1.27 1556.42 1.00 1066 118 153 43 TRUE 7.45
non-small cell lung cancer KRAS_G12C STK11 303 326 >65yrs 0.97 0.71 1.24 1457.49 1.00 1650 219 242 84 TRUE 11.67
non-small cell lung cancer KRAS_G12C STK11 475 541 Age:overall 0.96 0.47 1.53 1515.51 1.00 2890 345 411 130 TRUE 3.32
colorectal cancer KRAS_G12C DNMT1 10 18 40-50yrs -4.89 -11.57 -0.70 1421.94 1.00 412 10 18 0 FALSE 1.05
colorectal cancer KRAS_G12C DNMT1 29 36 50-65yrs -4.88 -11.47 -0.68 1403.11 1.00 879 29 36 0 FALSE 1.05
colorectal cancer KRAS_G12C DNMT1 22 23 >65yrs -4.88 -11.57 -0.73 1421.66 1.00 589 22 23 0 FALSE 1.05
colorectal cancer KRAS_G12C DNMT1 66 90 Age:overall -4.88 -11.60 -0.77 1413.18 1.00 2073 66 90 0 FALSE 1.05
colorectal cancer KRAS_G12C BRD4 31 40 50-65yrs -0.87 -3.68 0.77 845.75 1.00 901 31 40 0 FALSE 0.29
colorectal cancer KRAS_G12C BRD4 24 33 >65yrs -0.32 -2.19 1.12 761.63 1.00 596 22 31 2 FALSE 0.15
non-small cell lung cancer KRAS_G12C BRD4 152 15 50-65yrs -0.22 -1.46 0.80 1402.42 1.00 1149 151 14 1 FALSE 0.15
non-small cell lung cancer KRAS_G12C BRD4 292 37 >65yrs 0.02 -0.84 0.82 1396.49 1.00 1807 286 31 6 FALSE 0.02
colorectal cancer KRAS_G12C BRD4 55 73 Age:overall -0.58 -2.86 1.01 1063.28 1.00 1497 53 71 2 FALSE 0.26
non-small cell lung cancer KRAS_G12C BRD4 444 52 Age:overall -0.09 -1.28 0.96 1387.60 1.00 2956 437 45 7 FALSE 0.06
colorectal cancer KRAS_G12C ASXL1 10 21 40-50yrs -0.73 -2.78 0.63 345.43 1.01 421 10 21 0 TRUE 0.39
colorectal cancer KRAS_G12C ASXL1 31 40 50-65yrs -0.57 -2.36 0.83 424.57 1.01 900 29 38 2 TRUE 0.32
colorectal cancer KRAS_G12C ASXL1 23 40 >65yrs -0.76 -2.70 0.64 300.26 1.01 592 23 40 0 TRUE 0.42
non-small cell lung cancer KRAS_G12C ASXL1 152 29 50-65yrs -0.14 -1.00 0.65 819.23 1.00 1137 149 26 3 TRUE 0.13
non-small cell lung cancer KRAS_G12C ASXL1 291 53 >65yrs -0.11 -0.83 0.58 722.84 1.00 1805 284 46 7 TRUE 0.11
colorectal cancer KRAS_G12C ASXL1 64 101 Age:overall -0.68 -2.50 0.68 311.95 1.01 1913 62 99 2 TRUE 0.38
non-small cell lung cancer KRAS_G12C ASXL1 443 82 Age:overall -0.12 -1.02 0.69 1093.41 1.00 2942 433 72 10 TRUE 0.10
colorectal cancer KRAS_G12C EP300 6 15 <40yrs -1.87 -4.72 0.11 1346.72 1.00 199 6 15 0 TRUE 0.89
colorectal cancer KRAS_G12C EP300 10 16 40-50yrs -1.88 -4.61 0.18 1369.48 1.00 426 10 16 0 TRUE 0.92
colorectal cancer KRAS_G12C EP300 31 38 50-65yrs -1.75 -4.33 0.15 1346.01 1.00 907 30 37 1 TRUE 0.88
colorectal cancer KRAS_G12C EP300 23 56 >65yrs -1.93 -4.60 -0.15 1321.08 1.00 582 23 56 0 TRUE 0.99
non-small cell lung cancer KRAS_G12C EP300 152 30 50-65yrs 0.04 -0.83 0.95 1569.33 1.00 1140 147 25 5 TRUE 0.03
non-small cell lung cancer KRAS_G12C EP300 291 74 >65yrs -0.28 -1.07 0.38 1290.30 1.00 1779 284 67 7 TRUE 0.35
colorectal cancer KRAS_G12C EP300 70 125 Age:overall -1.85 -4.52 -0.03 1350.41 1.00 2114 69 124 1 TRUE 0.97
non-small cell lung cancer KRAS_G12C EP300 443 104 Age:overall -0.12 -1.13 0.96 1595.28 1.00 2919 431 92 12 TRUE 0.08
colorectal cancer KRAS_G12C ERBB4 7 17 <40yrs -1.11 -2.96 0.23 984.22 1.00 217 7 17 0 TRUE 0.75
colorectal cancer KRAS_G12C ERBB4 10 20 40-50yrs -1.12 -2.95 0.25 1044.36 1.00 458 10 20 0 TRUE 0.77
colorectal cancer KRAS_G12C ERBB4 39 60 50-65yrs -1.15 -2.90 0.16 1008.07 1.00 983 39 60 0 TRUE 0.80
colorectal cancer KRAS_G12C ERBB4 25 41 >65yrs -1.02 -2.80 0.26 991.01 1.00 660 23 39 2 TRUE 0.71
non-small cell lung cancer KRAS_G12C ERBB4 160 80 50-65yrs -0.64 -1.28 -0.02 898.43 1.00 1153 154 74 6 TRUE 1.31
non-small cell lung cancer KRAS_G12C ERBB4 300 105 >65yrs -0.68 -1.30 -0.11 1090.15 1.00 1800 292 97 8 TRUE 1.58
colorectal cancer KRAS_G12C ERBB4 81 138 Age:overall -1.10 -2.93 0.22 979.12 1.00 2318 79 136 2 TRUE 0.77
non-small cell lung cancer KRAS_G12C ERBB4 460 185 Age:overall -0.66 -1.40 0.06 1247.47 1.00 2953 446 171 14 TRUE 1.01
colorectal cancer KRAS_G12C MDC1 29 30 50-65yrs -4.59 -11.40 -0.25 789.62 1.00 885 29 30 0 FALSE 0.95
colorectal cancer KRAS_G12C MDC1 22 19 >65yrs -4.60 -11.53 -0.16 769.52 1.00 592 22 19 0 FALSE 0.94
non-small cell lung cancer KRAS_G12C MDC1 152 36 50-65yrs -0.65 -2.72 0.49 1192.28 1.00 1123 151 35 1 FALSE 0.36
non-small cell lung cancer KRAS_G12C MDC1 294 53 >65yrs 0.25 -0.49 0.97 1358.86 1.00 1794 283 42 11 FALSE 0.30
colorectal cancer KRAS_G12C MDC1 51 49 Age:overall -4.54 -11.36 -0.14 768.78 1.00 1477 51 49 0 FALSE 0.94
non-small cell lung cancer KRAS_G12C MDC1 446 89 Age:overall -0.19 -2.14 1.08 1421.72 1.00 2917 434 77 12 FALSE 0.10
colorectal cancer KRAS_G12C RECQL4 10 13 40-50yrs -4.86 -12.04 -0.46 889.53 1.00 414 10 13 0 TRUE 0.97
colorectal cancer KRAS_G12C RECQL4 29 34 50-65yrs -4.86 -12.02 -0.59 865.01 1.00 881 29 34 0 TRUE 0.97
colorectal cancer KRAS_G12C RECQL4 22 21 >65yrs -4.87 -12.10 -0.59 896.48 1.00 591 22 21 0 TRUE 0.98
non-small cell lung cancer KRAS_G12C RECQL4 152 25 50-65yrs -0.96 -2.34 0.10 625.96 1.00 1133 151 24 1 TRUE 0.90
non-small cell lung cancer KRAS_G12C RECQL4 291 35 >65yrs -0.84 -2.12 0.18 414.03 1.00 1801 288 32 3 TRUE 0.81
colorectal cancer KRAS_G12C RECQL4 66 81 Age:overall -4.86 -11.93 -0.52 884.89 1.00 2082 66 81 0 TRUE 0.98
non-small cell lung cancer KRAS_G12C RECQL4 443 60 Age:overall -0.90 -2.21 0.19 584.99 1.00 2934 439 56 4 TRUE 0.80
colorectal cancer KRAS_G12C MED12 6 13 <40yrs 0.47 -0.76 1.47 1173.73 1.00 200 6 13 0 TRUE 0.39
colorectal cancer KRAS_G12C MED12 10 18 40-50yrs 0.53 -0.55 1.49 1322.88 1.00 424 9 17 1 TRUE 0.50
colorectal cancer KRAS_G12C MED12 32 35 50-65yrs 0.58 -0.47 1.48 1362.10 1.00 911 29 32 3 TRUE 0.61
colorectal cancer KRAS_G12C MED12 23 42 >65yrs 0.50 -0.53 1.39 1328.84 1.00 591 21 40 2 TRUE 0.49
non-small cell lung cancer KRAS_G12C MED12 154 64 50-65yrs -0.06 -0.61 0.51 833.65 1.00 1112 146 56 8 TRUE 0.07
non-small cell lung cancer KRAS_G12C MED12 292 104 >65yrs -0.09 -0.60 0.40 809.32 1.00 1751 279 91 13 TRUE 0.14
colorectal cancer KRAS_G12C MED12 71 108 Age:overall 0.52 -0.51 1.43 1344.24 1.00 2126 65 102 6 TRUE 0.54
non-small cell lung cancer KRAS_G12C MED12 446 168 Age:overall -0.06 -0.65 0.52 1039.66 1.00 2863 425 147 21 TRUE 0.08
colorectal cancer KRAS_G12C ERCC5 10 13 40-50yrs -1.13 -4.24 0.88 1284.00 1.00 415 10 13 0 TRUE 0.41
colorectal cancer KRAS_G12C ERCC5 29 20 50-65yrs -1.17 -4.19 0.82 1232.93 1.00 891 29 20 0 TRUE 0.43
colorectal cancer KRAS_G12C ERCC5 22 22 >65yrs -1.05 -4.03 0.96 1206.39 1.00 592 21 21 1 TRUE 0.38
non-small cell lung cancer KRAS_G12C ERCC5 152 28 50-65yrs 0.33 -0.42 1.02 1180.96 1.00 1135 147 23 5 TRUE 0.43
non-small cell lung cancer KRAS_G12C ERCC5 291 43 >65yrs 0.26 -0.47 0.91 1369.07 1.00 1799 284 36 7 TRUE 0.32
colorectal cancer KRAS_G12C ERCC5 61 55 Age:overall -1.11 -4.06 0.85 1232.56 1.00 1898 60 54 1 TRUE 0.41
non-small cell lung cancer KRAS_G12C ERCC5 443 71 Age:overall 0.30 -0.54 1.07 1197.69 1.00 2934 431 59 12 TRUE 0.31
colorectal cancer KRAS_G12C PIK3CD 10 17 40-50yrs -0.10 -2.13 1.51 519.10 1.01 412 9 16 1 FALSE 0.04
colorectal cancer KRAS_G12C PIK3CD 29 18 50-65yrs -0.16 -2.13 1.30 441.64 1.01 893 28 17 1 FALSE 0.07
colorectal cancer KRAS_G12C PIK3CD 22 31 >65yrs -0.43 -2.57 0.93 232.75 1.01 584 22 31 0 FALSE 0.19
colorectal cancer KRAS_G12C PIK3CD 61 66 Age:overall -0.22 -2.08 1.17 288.17 1.01 1889 59 64 2 FALSE 0.10
colorectal cancer KRAS_G12C BRCA1 6 19 <40yrs -4.94 -11.95 -0.60 1117.86 1.00 200 6 19 0 TRUE 1.00
colorectal cancer KRAS_G12C BRCA1 10 15 40-50yrs -4.94 -12.06 -0.51 1104.41 1.00 427 10 15 0 TRUE 0.99
colorectal cancer KRAS_G12C BRCA1 31 19 50-65yrs -4.94 -11.81 -0.62 1221.00 1.00 918 31 19 0 TRUE 1.01
colorectal cancer KRAS_G12C BRCA1 23 26 >65yrs -4.93 -12.06 -0.64 1171.87 1.00 604 23 26 0 TRUE 1.00
non-small cell lung cancer KRAS_G12C BRCA1 152 32 50-65yrs -0.03 -0.91 0.65 1316.80 1.00 1135 149 29 3 TRUE 0.02
non-small cell lung cancer KRAS_G12C BRCA1 291 61 >65yrs 0.09 -0.63 0.69 1190.36 1.00 1790 281 51 10 TRUE 0.10
colorectal cancer KRAS_G12C BRCA1 70 79 Age:overall -4.92 -11.91 -0.70 1150.55 1.00 2149 70 79 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C BRCA1 443 93 Age:overall 0.02 -0.91 0.80 1216.16 1.00 2925 430 80 13 TRUE 0.02
colorectal cancer KRAS_G12C RBM10 31 38 50-65yrs -4.57 -11.06 -0.28 761.55 1.00 900 31 38 0 FALSE 0.96
colorectal cancer KRAS_G12C RBM10 23 22 >65yrs -4.58 -11.08 -0.31 748.17 1.00 608 23 22 0 FALSE 0.94
non-small cell lung cancer KRAS_G12C RBM10 11 11 40-50yrs 0.13 -1.57 1.22 1504.60 1.00 170 11 11 0 FALSE 0.07
non-small cell lung cancer KRAS_G12C RBM10 154 106 50-65yrs 0.89 0.43 1.37 1397.75 1.00 1090 128 80 26 FALSE 3.66
non-small cell lung cancer KRAS_G12C RBM10 293 265 >65yrs 0.36 0.02 0.69 1427.37 1.00 1626 247 219 46 FALSE 1.46
colorectal cancer KRAS_G12C RBM10 54 60 Age:overall -4.54 -11.04 -0.26 734.96 1.00 1508 54 60 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C RBM10 458 382 Age:overall 0.44 -0.65 1.26 1378.94 1.00 2886 386 310 72 FALSE 0.49
colorectal cancer KRAS_G12C TSC1 31 23 50-65yrs -1.28 -4.53 0.81 1049.46 1.00 916 31 23 0 TRUE 0.43
colorectal cancer KRAS_G12C TSC1 23 27 >65yrs -0.88 -3.77 1.03 886.44 1.00 605 22 26 1 TRUE 0.33
non-small cell lung cancer KRAS_G12C TSC1 152 23 50-65yrs 0.18 -0.96 1.01 1358.83 1.00 1143 150 21 2 TRUE 0.15
non-small cell lung cancer KRAS_G12C TSC1 291 33 >65yrs 0.42 -0.37 1.16 1292.36 1.00 1812 283 25 8 TRUE 0.57
colorectal cancer KRAS_G12C TSC1 54 50 Age:overall -1.07 -4.00 1.05 980.80 1.00 1521 53 49 1 TRUE 0.40
non-small cell lung cancer KRAS_G12C TSC1 443 56 Age:overall 0.32 -0.71 1.22 1465.55 1.00 2955 433 46 10 TRUE 0.26
colorectal cancer KRAS_G12C FLCN 31 23 50-65yrs -4.55 -11.93 -0.14 324.21 1.00 918 31 23 0 TRUE 0.84
colorectal cancer KRAS_G12C FLCN 23 19 >65yrs -4.55 -12.21 -0.02 331.63 1.01 607 23 19 0 TRUE 0.83
colorectal cancer KRAS_G12C FLCN 54 42 Age:overall -4.52 -12.09 -0.04 330.39 1.01 1525 54 42 0 TRUE 0.83
colorectal cancer KRAS_G12C NF1 6 23 <40yrs -2.04 -4.90 -0.08 1367.98 1.00 196 6 23 0 TRUE 1.03
colorectal cancer KRAS_G12C NF1 10 21 40-50yrs -2.04 -5.03 -0.05 1219.65 1.00 427 10 21 0 TRUE 1.02
colorectal cancer KRAS_G12C NF1 31 58 50-65yrs -1.97 -4.77 -0.10 1201.76 1.00 888 30 57 1 TRUE 1.03
colorectal cancer KRAS_G12C NF1 23 40 >65yrs -2.03 -4.83 -0.15 1240.25 1.00 597 23 40 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C NF1 11 12 40-50yrs -0.51 -1.62 0.37 1472.84 1.00 170 11 12 0 TRUE 0.52
non-small cell lung cancer KRAS_G12C NF1 153 110 50-65yrs -0.24 -0.82 0.32 1487.92 1.00 1080 141 98 12 TRUE 0.38
non-small cell lung cancer KRAS_G12C NF1 293 191 >65yrs -0.45 -0.96 -0.01 1361.33 1.00 1688 276 174 17 TRUE 1.23
colorectal cancer KRAS_G12C NF1 70 142 Age:overall -2.02 -4.85 -0.16 1241.58 1.00 2108 69 141 1 TRUE 1.07
non-small cell lung cancer KRAS_G12C NF1 457 313 Age:overall -0.40 -1.19 0.31 1461.64 1.00 2938 428 284 29 TRUE 0.56
colorectal cancer KRAS_G12C FLT1 10 13 40-50yrs -4.88 -11.69 -0.60 1412.44 1.00 430 10 13 0 FALSE 1.03
colorectal cancer KRAS_G12C FLT1 31 40 50-65yrs -4.88 -11.69 -0.77 1397.67 1.00 903 31 40 0 FALSE 1.05
colorectal cancer KRAS_G12C FLT1 23 25 >65yrs -4.89 -11.53 -0.69 1410.27 1.00 606 23 25 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C FLT1 153 51 50-65yrs 0.47 -0.28 0.97 16.46 1.19 1123 146 44 7 FALSE 0.75
non-small cell lung cancer KRAS_G12C FLT1 293 80 >65yrs 0.58 0.04 0.99 24.27 1.13 1780 275 62 18 FALSE 1.53
colorectal cancer KRAS_G12C FLT1 64 78 Age:overall -4.88 -11.59 -0.73 1404.55 1.00 1939 64 78 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C FLT1 446 131 Age:overall 0.53 -0.12 1.04 21.82 1.13 2903 421 106 25 FALSE 0.92
colorectal cancer KRAS_G12C RPTOR 10 16 40-50yrs -1.26 -4.19 0.70 568.49 1.00 427 10 16 0 FALSE 0.49
colorectal cancer KRAS_G12C RPTOR 31 23 50-65yrs -1.30 -4.33 0.63 569.79 1.00 914 31 23 0 FALSE 0.51
colorectal cancer KRAS_G12C RPTOR 23 24 >65yrs -1.17 -4.08 0.68 576.46 1.00 606 22 23 1 FALSE 0.45
non-small cell lung cancer KRAS_G12C RPTOR 152 22 50-65yrs -0.11 -1.13 0.78 1400.84 1.00 1143 150 20 2 FALSE 0.09
non-small cell lung cancer KRAS_G12C RPTOR 291 40 >65yrs -0.03 -0.84 0.74 1452.51 1.00 1804 285 34 6 FALSE 0.03
colorectal cancer KRAS_G12C RPTOR 64 63 Age:overall -1.24 -4.13 0.64 575.98 1.00 1947 63 62 1 FALSE 0.49
non-small cell lung cancer KRAS_G12C RPTOR 443 62 Age:overall -0.07 -1.04 0.84 1511.71 1.00 2947 435 54 8 FALSE 0.05
colorectal cancer KRAS_G12C RASA1 10 21 40-50yrs -1.34 -4.49 0.58 343.37 1.00 425 10 21 0 FALSE 0.52
colorectal cancer KRAS_G12C RASA1 31 24 50-65yrs -1.21 -4.40 0.67 321.36 1.00 919 30 23 1 FALSE 0.47
colorectal cancer KRAS_G12C RASA1 23 20 >65yrs -1.37 -4.71 0.60 367.50 1.00 611 23 20 0 FALSE 0.52
non-small cell lung cancer KRAS_G12C RASA1 152 26 50-65yrs -0.98 -2.27 0.12 1453.16 1.00 1139 150 24 2 FALSE 0.99
non-small cell lung cancer KRAS_G12C RASA1 291 67 >65yrs -1.17 -2.34 -0.24 1340.05 1.00 1775 288 64 3 FALSE 1.57
colorectal cancer KRAS_G12C RASA1 64 65 Age:overall -1.31 -4.49 0.55 343.15 1.00 1955 63 64 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C RASA1 443 93 Age:overall -1.07 -2.40 0.18 1324.21 1.00 2914 438 88 5 FALSE 0.95
colorectal cancer KRAS_G12C EPHA5 6 17 <40yrs -1.12 -2.88 0.33 593.06 1.01 197 6 17 0 FALSE 0.77
colorectal cancer KRAS_G12C EPHA5 10 27 40-50yrs -1.12 -2.85 0.31 711.21 1.01 422 10 27 0 FALSE 0.78
colorectal cancer KRAS_G12C EPHA5 31 46 50-65yrs -1.07 -2.85 0.30 686.75 1.01 897 30 45 1 FALSE 0.75
colorectal cancer KRAS_G12C EPHA5 23 54 >65yrs -1.06 -2.82 0.32 555.17 1.01 581 22 53 1 FALSE 0.75
non-small cell lung cancer KRAS_G12C EPHA5 153 99 50-65yrs 0.55 0.16 0.94 1239.14 1.01 1094 135 81 18 FALSE 2.37
non-small cell lung cancer KRAS_G12C EPHA5 292 151 >65yrs 0.56 0.21 0.91 422.24 1.01 1728 260 119 32 FALSE 2.82
colorectal cancer KRAS_G12C EPHA5 70 144 Age:overall -1.10 -2.79 0.25 532.63 1.01 2097 68 142 2 FALSE 0.80
non-small cell lung cancer KRAS_G12C EPHA5 445 250 Age:overall 0.55 0.09 1.03 887.99 1.01 2822 395 200 50 FALSE 1.63
colorectal cancer KRAS_G12C AR 10 22 40-50yrs -5.08 -12.11 -0.86 327.98 1.01 421 10 22 0 TRUE 1.05
colorectal cancer KRAS_G12C AR 31 38 50-65yrs -5.09 -12.13 -1.04 304.99 1.01 899 31 38 0 TRUE 1.08
colorectal cancer KRAS_G12C AR 23 48 >65yrs -5.10 -12.09 -0.86 322.31 1.01 585 23 48 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C AR 154 48 50-65yrs 0.24 -0.55 0.87 964.50 1.00 1125 148 42 6 TRUE 0.31
non-small cell lung cancer KRAS_G12C AR 292 55 >65yrs 0.42 -0.16 1.03 1046.44 1.00 1796 280 43 12 TRUE 0.80
colorectal cancer KRAS_G12C AR 64 108 Age:overall -5.05 -12.10 -0.97 320.33 1.01 1905 64 108 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C AR 446 103 Age:overall 0.32 -0.50 1.12 1177.87 1.00 2921 428 85 18 TRUE 0.36
colorectal cancer KRAS_G12C GNAS 10 16 40-50yrs -4.74 -11.40 -0.51 1211.73 1.00 458 10 16 0 TRUE 1.00
colorectal cancer KRAS_G12C GNAS 39 29 50-65yrs -4.76 -11.47 -0.59 1247.52 1.00 1009 39 29 0 TRUE 1.02
colorectal cancer KRAS_G12C GNAS 25 25 >65yrs -4.75 -11.34 -0.55 1180.00 1.00 673 25 25 0 TRUE 1.02
colorectal cancer KRAS_G12C GNAS 74 70 Age:overall -4.74 -11.37 -0.52 1245.32 1.00 2140 74 70 0 TRUE 1.01
colorectal cancer KRAS_G12C ASXL2 10 16 40-50yrs -1.06 -3.86 0.89 247.41 1.02 431 10 16 0 FALSE 0.44
colorectal cancer KRAS_G12C ASXL2 31 26 50-65yrs -1.09 -3.63 0.83 263.08 1.02 916 31 26 0 FALSE 0.46
colorectal cancer KRAS_G12C ASXL2 23 20 >65yrs -1.00 -3.64 0.89 294.18 1.02 610 22 19 1 FALSE 0.41
non-small cell lung cancer KRAS_G12C ASXL2 152 22 50-65yrs 0.52 -0.40 1.22 1188.51 1.00 1144 149 19 3 FALSE 0.67
non-small cell lung cancer KRAS_G12C ASXL2 292 36 >65yrs 0.71 0.06 1.35 1302.08 1.00 1813 282 26 10 FALSE 1.46
colorectal cancer KRAS_G12C ASXL2 64 62 Age:overall -1.05 -3.66 0.82 251.61 1.02 1957 63 61 1 FALSE 0.44
non-small cell lung cancer KRAS_G12C ASXL2 444 58 Age:overall 0.62 -0.28 1.43 1302.78 1.00 2957 431 45 13 FALSE 0.72
colorectal cancer KRAS_G12C SF3B1 10 16 40-50yrs -4.11 -11.28 -0.20 100.19 1.05 428 10 16 0 TRUE 0.79
colorectal cancer KRAS_G12C SF3B1 31 24 50-65yrs -4.12 -11.37 -0.23 101.25 1.05 916 31 24 0 TRUE 0.79
colorectal cancer KRAS_G12C SF3B1 23 24 >65yrs -4.11 -11.45 -0.20 100.19 1.05 609 23 24 0 TRUE 0.78
non-small cell lung cancer KRAS_G12C SF3B1 152 36 50-65yrs -1.45 -5.16 0.01 339.86 1.01 1127 152 36 0 TRUE 0.54
non-small cell lung cancer KRAS_G12C SF3B1 293 49 >65yrs -0.52 -1.56 0.31 724.14 1.00 1797 287 43 6 TRUE 0.58
colorectal cancer KRAS_G12C SF3B1 64 64 Age:overall -4.10 -11.37 -0.20 102.03 1.05 1953 64 64 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C SF3B1 445 85 Age:overall -0.94 -3.43 0.44 852.40 1.00 2924 439 79 6 TRUE 0.49
colorectal cancer KRAS_G12C MLH1 39 25 50-65yrs -4.10 -10.31 0.90 33.72 1.10 1014 39 25 0 TRUE 0.78
colorectal cancer KRAS_G12C MLH1 25 12 >65yrs -4.14 -10.44 0.79 32.83 1.10 686 25 12 0 TRUE 0.80
colorectal cancer KRAS_G12C MLH1 64 37 Age:overall -4.07 -9.82 0.81 31.60 1.10 1700 64 37 0 TRUE 0.80
colorectal cancer KRAS_G12C ROS1 10 19 40-50yrs -1.57 -4.21 0.29 1316.86 1.00 424 10 19 0 TRUE 0.77
colorectal cancer KRAS_G12C ROS1 31 43 50-65yrs -1.52 -4.18 0.32 1321.58 1.00 903 30 42 1 TRUE 0.74
colorectal cancer KRAS_G12C ROS1 23 31 >65yrs -1.57 -4.29 0.29 1340.82 1.00 600 23 31 0 TRUE 0.77
non-small cell lung cancer KRAS_G12C ROS1 152 37 50-65yrs -0.51 -1.41 0.26 1159.02 1.00 1129 149 34 3 TRUE 0.63
non-small cell lung cancer KRAS_G12C ROS1 292 66 >65yrs -0.52 -1.31 0.15 1121.90 1.00 1781 286 60 6 TRUE 0.77
colorectal cancer KRAS_G12C ROS1 64 93 Age:overall -1.55 -4.21 0.27 1331.79 1.00 1927 63 92 1 TRUE 0.77
non-small cell lung cancer KRAS_G12C ROS1 444 103 Age:overall -0.52 -1.49 0.33 1210.95 1.00 2910 435 94 9 TRUE 0.55
colorectal cancer KRAS_G12C PIK3R2 10 11 40-50yrs -4.64 -11.67 0.03 1320.83 1.00 431 10 11 0 FALSE 0.84
colorectal cancer KRAS_G12C PIK3R2 31 13 50-65yrs -4.65 -11.60 -0.05 1319.64 1.00 923 31 13 0 FALSE 0.85
colorectal cancer KRAS_G12C PIK3R2 23 21 >65yrs -4.68 -11.53 0.02 1317.64 1.00 607 23 21 0 FALSE 0.86
colorectal cancer KRAS_G12C PIK3R2 64 45 Age:overall -4.63 -11.67 0.01 1319.04 1.00 1961 64 45 0 FALSE 0.85
colorectal cancer KRAS_G12C FLT3 39 17 50-65yrs -4.11 -11.22 0.01 724.17 1.01 1020 39 17 0 TRUE 0.82
colorectal cancer KRAS_G12C FLT3 25 17 >65yrs -4.13 -11.34 0.06 735.68 1.01 680 25 17 0 TRUE 0.82
non-small cell lung cancer KRAS_G12C FLT3 160 31 50-65yrs 0.23 -0.51 0.93 908.75 1.00 1190 155 26 5 TRUE 0.26
non-small cell lung cancer KRAS_G12C FLT3 300 44 >65yrs 0.20 -0.51 0.84 933.78 1.00 1848 293 37 7 TRUE 0.24
colorectal cancer KRAS_G12C FLT3 64 34 Age:overall -4.09 -11.28 0.05 693.54 1.01 1700 64 34 0 TRUE 0.82
non-small cell lung cancer KRAS_G12C FLT3 460 75 Age:overall 0.20 -0.65 0.93 1031.81 1.00 3038 448 63 12 TRUE 0.19
colorectal cancer KRAS_G12C MSH2 10 24 40-50yrs -1.37 -4.06 0.48 1117.82 1.00 426 10 24 0 TRUE 0.62
colorectal cancer KRAS_G12C MSH2 31 26 50-65yrs -1.37 -4.07 0.47 1179.96 1.00 914 31 26 0 TRUE 0.62
colorectal cancer KRAS_G12C MSH2 23 23 >65yrs -1.19 -3.74 0.61 1102.28 1.00 611 22 22 1 TRUE 0.53
non-small cell lung cancer KRAS_G12C MSH2 152 18 50-65yrs -0.60 -1.85 0.50 582.09 1.01 1147 151 17 1 TRUE 0.49
non-small cell lung cancer KRAS_G12C MSH2 291 37 >65yrs -0.50 -1.55 0.45 386.10 1.01 1807 287 33 4 TRUE 0.50
colorectal cancer KRAS_G12C MSH2 64 73 Age:overall -1.30 -3.90 0.48 1077.41 1.00 1951 63 72 1 TRUE 0.61
non-small cell lung cancer KRAS_G12C MSH2 443 55 Age:overall -0.55 -1.70 0.56 655.55 1.00 2954 438 50 5 TRUE 0.41
non-small cell lung cancer KRAS_G12C DIS3 152 27 50-65yrs 0.55 -0.25 1.26 1434.65 1.00 1141 147 22 5 FALSE 0.78
non-small cell lung cancer KRAS_G12C DIS3 291 34 >65yrs 0.58 -0.16 1.25 1231.16 1.00 1813 283 26 8 FALSE 0.99
non-small cell lung cancer KRAS_G12C DIS3 443 61 Age:overall 0.56 -0.43 1.37 1586.19 1.00 2954 430 48 13 FALSE 0.62
colorectal cancer KRAS_G12C AXL 6 13 <40yrs -1.39 -3.72 0.40 684.56 1.02 201 6 13 0 FALSE 0.71
colorectal cancer KRAS_G12C AXL 10 16 40-50yrs -1.42 -3.88 0.32 689.79 1.01 428 10 16 0 FALSE 0.73
colorectal cancer KRAS_G12C AXL 31 30 50-65yrs -1.36 -3.80 0.42 657.39 1.02 912 30 29 1 FALSE 0.70
colorectal cancer KRAS_G12C AXL 23 29 >65yrs -1.42 -3.88 0.31 622.26 1.01 600 23 29 0 FALSE 0.74
colorectal cancer KRAS_G12C AXL 70 88 Age:overall -1.39 -3.77 0.33 662.32 1.02 2141 69 87 1 FALSE 0.73
colorectal cancer KRAS_G12C PIK3CG 10 22 40-50yrs -5.05 -11.60 -0.90 534.07 1.01 423 10 22 0 FALSE 1.12
colorectal cancer KRAS_G12C PIK3CG 31 37 50-65yrs -5.05 -11.51 -0.87 505.30 1.01 905 31 37 0 FALSE 1.13
colorectal cancer KRAS_G12C PIK3CG 23 42 >65yrs -5.07 -11.53 -0.92 494.25 1.01 587 23 42 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C PIK3CG 152 69 50-65yrs 0.36 -0.15 0.89 1315.10 1.00 1112 140 57 12 FALSE 0.77
non-small cell lung cancer KRAS_G12C PIK3CG 294 105 >65yrs 0.28 -0.19 0.69 1405.15 1.00 1759 277 88 17 FALSE 0.65
colorectal cancer KRAS_G12C PIK3CG 64 101 Age:overall -5.06 -11.48 -0.98 519.71 1.01 1915 64 101 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C PIK3CG 446 174 Age:overall 0.32 -0.22 0.93 1254.01 1.00 2871 417 145 29 FALSE 0.53
colorectal cancer KRAS_G12C MAP2K4 10 11 40-50yrs -0.69 -3.50 0.80 13.36 1.23 429 10 11 0 TRUE 0.22
colorectal cancer KRAS_G12C MAP2K4 31 29 50-65yrs -0.72 -3.57 0.80 12.53 1.24 909 31 29 0 TRUE 0.23
colorectal cancer KRAS_G12C MAP2K4 23 18 >65yrs -0.66 -3.29 0.76 12.65 1.23 610 22 17 1 TRUE 0.21
colorectal cancer KRAS_G12C MAP2K4 64 58 Age:overall -0.69 -3.40 0.77 12.66 1.24 1948 63 57 1 TRUE 0.22
colorectal cancer KRAS_G12C EGFR 10 12 40-50yrs -4.38 -11.14 -0.56 199.52 1.02 463 10 12 0 TRUE 0.92
colorectal cancer KRAS_G12C EGFR 39 27 50-65yrs -4.39 -10.93 -0.63 175.27 1.02 1010 39 27 0 TRUE 0.93
colorectal cancer KRAS_G12C EGFR 25 23 >65yrs -4.38 -11.06 -0.52 172.06 1.02 676 25 23 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C EGFR 11 68 40-50yrs -3.19 -4.65 -1.94 1277.76 1.00 136 11 68 0 TRUE 5.75
non-small cell lung cancer KRAS_G12C EGFR 159 403 50-65yrs -3.06 -3.97 -2.27 1428.27 1.00 878 155 399 4 TRUE 12.05
non-small cell lung cancer KRAS_G12C EGFR 300 550 >65yrs -3.13 -3.98 -2.41 1435.99 1.00 1444 295 545 5 TRUE 14.43
colorectal cancer KRAS_G12C EGFR 74 62 Age:overall -4.36 -11.04 -0.53 179.01 1.02 2149 74 62 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C EGFR 471 1042 Age:overall -3.13 -4.14 -2.28 1369.66 1.00 2504 462 1033 9 TRUE 10.52
colorectal cancer KRAS_G12C ARID1B 6 11 <40yrs -5.24 -12.00 -1.09 617.53 1.00 204 6 11 0 TRUE 1.16
colorectal cancer KRAS_G12C ARID1B 10 22 40-50yrs -5.24 -11.95 -1.08 623.11 1.00 425 10 22 0 TRUE 1.16
colorectal cancer KRAS_G12C ARID1B 31 54 50-65yrs -5.25 -11.97 -1.21 617.47 1.00 890 31 54 0 TRUE 1.17
colorectal cancer KRAS_G12C ARID1B 23 53 >65yrs -5.25 -12.11 -1.11 639.36 1.00 577 23 53 0 TRUE 1.16
non-small cell lung cancer KRAS_G12C ARID1B 152 43 50-65yrs -0.01 -0.80 0.66 637.04 1.00 1126 148 39 4 TRUE 0.01
non-small cell lung cancer KRAS_G12C ARID1B 292 64 >65yrs 0.12 -0.52 0.70 751.83 1.00 1787 281 53 11 TRUE 0.16
colorectal cancer KRAS_G12C ARID1B 70 140 Age:overall -5.24 -11.90 -1.13 625.28 1.00 2096 70 140 0 TRUE 1.17
non-small cell lung cancer KRAS_G12C ARID1B 444 107 Age:overall 0.05 -0.85 0.78 994.87 1.00 2913 429 92 15 TRUE 0.04
non-small cell lung cancer KRAS_G12C INSR 152 23 50-65yrs -0.63 -1.87 0.44 1282.25 1.00 1139 150 21 2 FALSE 0.55
non-small cell lung cancer KRAS_G12C INSR 291 28 >65yrs -0.72 -1.99 0.26 1237.86 1.00 1804 289 26 2 FALSE 0.68
non-small cell lung cancer KRAS_G12C INSR 443 51 Age:overall -0.68 -2.03 0.50 1360.57 1.00 2943 439 47 4 FALSE 0.52
non-small cell lung cancer KRAS_G12C NKX2-1 152 31 50-65yrs 0.42 -0.40 1.07 1247.74 1.00 1139 148 27 4 TRUE 0.54
non-small cell lung cancer KRAS_G12C NKX2-1 294 42 >65yrs 0.61 -0.08 1.28 1330.77 1.00 1810 283 31 11 TRUE 1.18
non-small cell lung cancer KRAS_G12C NKX2-1 446 73 Age:overall 0.52 -0.44 1.32 1376.98 1.00 2949 431 58 15 TRUE 0.61
colorectal cancer KRAS_G12C ARID5B 10 20 40-50yrs -4.80 -12.29 -0.33 867.32 1.00 429 10 20 0 FALSE 0.91
colorectal cancer KRAS_G12C ARID5B 31 22 50-65yrs -4.78 -12.33 -0.32 848.82 1.00 916 31 22 0 FALSE 0.90
colorectal cancer KRAS_G12C ARID5B 23 17 >65yrs -4.79 -12.37 -0.24 825.58 1.00 611 23 17 0 FALSE 0.91
colorectal cancer KRAS_G12C ARID5B 64 59 Age:overall -4.77 -12.29 -0.29 839.43 1.00 1956 64 59 0 FALSE 0.91
non-small cell lung cancer KRAS_G12C WT1 152 30 50-65yrs -0.30 -1.36 0.67 1007.71 1.00 1137 148 26 4 TRUE 0.25
non-small cell lung cancer KRAS_G12C WT1 291 36 >65yrs -0.65 -1.94 0.31 1462.78 1.00 1807 289 34 2 TRUE 0.61
non-small cell lung cancer KRAS_G12C WT1 443 66 Age:overall -0.48 -1.68 0.65 1340.79 1.00 2944 437 60 6 TRUE 0.33
non-small cell lung cancer KRAS_G12C MET 159 48 50-65yrs -1.01 -2.00 -0.06 1391.24 1.00 1176 156 45 3 TRUE 1.45
non-small cell lung cancer KRAS_G12C MET 300 111 >65yrs -1.19 -2.06 -0.48 1406.94 1.00 1786 295 106 5 TRUE 2.47
non-small cell lung cancer KRAS_G12C MET 459 159 Age:overall -1.09 -2.16 -0.04 1499.46 1.00 2962 451 151 8 TRUE 1.33
non-small cell lung cancer KRAS_G12C PMS1 152 17 50-65yrs 0.11 -0.97 1.00 1458.23 1.00 1148 150 15 2 TRUE 0.08
non-small cell lung cancer KRAS_G12C PMS1 291 35 >65yrs 0.18 -0.70 0.97 1427.05 1.00 1809 285 29 6 TRUE 0.17
non-small cell lung cancer KRAS_G12C PMS1 443 52 Age:overall 0.14 -0.91 1.09 1451.57 1.00 2957 435 44 8 TRUE 0.10
non-small cell lung cancer KRAS_G12C PIK3C3 152 29 50-65yrs -0.40 -1.38 0.42 1216.59 1.00 1132 149 26 3 FALSE 0.41
non-small cell lung cancer KRAS_G12C PIK3C3 291 44 >65yrs -0.45 -1.33 0.35 1357.98 1.00 1791 287 40 4 FALSE 0.52
non-small cell lung cancer KRAS_G12C PIK3C3 443 73 Age:overall -0.43 -1.43 0.42 1220.08 1.00 2923 436 66 7 FALSE 0.43
colorectal cancer KRAS_G12C BRAF 7 21 <40yrs -5.73 -12.46 -1.80 1243.40 1.00 209 7 21 0 TRUE 1.37
colorectal cancer KRAS_G12C BRAF 10 34 40-50yrs -5.73 -12.30 -1.77 1260.98 1.00 442 10 34 0 TRUE 1.38
colorectal cancer KRAS_G12C BRAF 39 93 50-65yrs -5.72 -12.51 -1.78 1218.43 1.00 944 39 93 0 TRUE 1.40
colorectal cancer KRAS_G12C BRAF 25 105 >65yrs -5.72 -12.34 -1.91 1234.08 1.00 599 25 105 0 TRUE 1.40
non-small cell lung cancer KRAS_G12C BRAF 159 62 50-65yrs -1.36 -2.40 -0.54 1178.34 1.00 1155 157 60 2 TRUE 2.43
non-small cell lung cancer KRAS_G12C BRAF 300 122 >65yrs -1.28 -2.05 -0.57 1159.23 1.00 1769 294 116 6 TRUE 3.04
colorectal cancer KRAS_G12C BRAF 81 253 Age:overall -5.71 -12.41 -1.77 1243.74 1.00 2194 81 253 0 TRUE 1.40
non-small cell lung cancer KRAS_G12C BRAF 459 184 Age:overall -1.31 -2.22 -0.51 962.85 1.00 2924 451 176 8 TRUE 2.22
colorectal cancer KRAS_G12C B2M 10 21 40-50yrs -0.57 -2.10 0.70 1416.74 1.00 415 10 21 0 FALSE 0.37
colorectal cancer KRAS_G12C B2M 29 52 50-65yrs -0.64 -2.10 0.55 1429.62 1.00 876 29 52 0 FALSE 0.44
colorectal cancer KRAS_G12C B2M 23 54 >65yrs -0.41 -1.82 0.74 1320.81 1.00 581 20 51 3 FALSE 0.26
colorectal cancer KRAS_G12C B2M 67 139 Age:overall -0.55 -1.94 0.63 1368.67 1.00 2067 64 136 3 FALSE 0.38
colorectal cancer KRAS_G12C TGFBR1 29 18 50-65yrs -0.94 -4.05 1.08 623.01 1.00 895 29 18 0 FALSE 0.33
colorectal cancer KRAS_G12C TGFBR1 22 13 >65yrs -0.69 -3.56 1.31 618.44 1.00 599 21 12 1 FALSE 0.23
non-small cell lung cancer KRAS_G12C TGFBR1 152 16 50-65yrs 0.81 -0.08 1.66 1254.56 1.00 1146 147 11 5 FALSE 1.14
non-small cell lung cancer KRAS_G12C TGFBR1 291 31 >65yrs 0.61 -0.24 1.34 1224.96 1.00 1805 285 25 6 FALSE 0.89
colorectal cancer KRAS_G12C TGFBR1 56 42 Age:overall -0.83 -3.66 1.22 574.78 1.00 1690 55 41 1 FALSE 0.30
non-small cell lung cancer KRAS_G12C TGFBR1 443 47 Age:overall 0.70 -0.32 1.66 1224.41 1.00 2951 432 36 11 FALSE 0.76
colorectal cancer KRAS_G12C TET2 6 16 <40yrs -4.99 -11.74 -0.70 439.79 1.00 200 6 16 0 TRUE 1.13
colorectal cancer KRAS_G12C TET2 10 19 40-50yrs -5.01 -11.61 -0.85 444.67 1.00 426 10 19 0 TRUE 1.14
colorectal cancer KRAS_G12C TET2 31 29 50-65yrs -5.01 -11.58 -0.79 440.29 1.00 910 31 29 0 TRUE 1.14
colorectal cancer KRAS_G12C TET2 23 27 >65yrs -5.00 -11.68 -0.85 469.81 1.00 604 23 27 0 TRUE 1.14
non-small cell lung cancer KRAS_G12C TET2 152 33 50-65yrs -0.85 -2.22 0.08 1435.93 1.00 1134 151 32 1 TRUE 0.86
non-small cell lung cancer KRAS_G12C TET2 291 45 >65yrs -0.62 -1.48 0.21 816.58 1.01 1799 286 40 5 TRUE 0.81
colorectal cancer KRAS_G12C TET2 70 91 Age:overall -4.99 -11.69 -0.84 442.12 1.00 2140 70 91 0 TRUE 1.14
non-small cell lung cancer KRAS_G12C TET2 443 78 Age:overall -0.73 -1.88 0.24 1390.46 1.00 2933 437 72 6 TRUE 0.77
colorectal cancer KRAS_G12C PDGFRB 10 11 40-50yrs -1.02 -4.05 1.02 948.50 1.00 429 10 11 0 TRUE 0.34
colorectal cancer KRAS_G12C PDGFRB 31 11 50-65yrs -1.00 -3.93 1.00 1081.50 1.00 925 31 11 0 TRUE 0.35
colorectal cancer KRAS_G12C PDGFRB 23 24 >65yrs -0.79 -3.44 1.08 1137.93 1.00 603 22 23 1 TRUE 0.30
non-small cell lung cancer KRAS_G12C PDGFRB 154 33 50-65yrs 0.40 -0.34 1.06 1199.65 1.00 1137 148 27 6 TRUE 0.64
non-small cell lung cancer KRAS_G12C PDGFRB 292 55 >65yrs 0.37 -0.29 0.95 1307.18 1.00 1797 282 45 10 TRUE 0.68
colorectal cancer KRAS_G12C PDGFRB 64 46 Age:overall -0.94 -3.81 1.06 991.73 1.00 1957 63 45 1 TRUE 0.35
non-small cell lung cancer KRAS_G12C PDGFRB 446 88 Age:overall 0.40 -0.34 1.10 1233.78 1.00 2934 430 72 16 TRUE 0.55
colorectal cancer KRAS_G12C CARD11 6 21 <40yrs -0.09 -1.49 1.18 1312.54 1.00 193 5 20 1 FALSE 0.05
colorectal cancer KRAS_G12C CARD11 10 20 40-50yrs -0.09 -1.50 1.15 1279.61 1.00 423 9 19 1 FALSE 0.05
colorectal cancer KRAS_G12C CARD11 31 45 50-65yrs -0.26 -1.63 0.86 1346.60 1.00 895 31 45 0 FALSE 0.17
colorectal cancer KRAS_G12C CARD11 23 42 >65yrs -0.10 -1.40 1.02 1232.00 1.00 591 21 40 2 FALSE 0.06
non-small cell lung cancer KRAS_G12C CARD11 152 50 50-65yrs 0.32 -0.29 0.89 1504.59 1.00 1122 144 42 8 FALSE 0.55
non-small cell lung cancer KRAS_G12C CARD11 292 75 >65yrs 0.30 -0.27 0.83 1510.87 1.00 1780 279 62 13 FALSE 0.58
colorectal cancer KRAS_G12C CARD11 70 128 Age:overall -0.14 -1.43 0.97 1193.91 1.00 2102 66 124 4 FALSE 0.09
non-small cell lung cancer KRAS_G12C CARD11 444 125 Age:overall 0.31 -0.38 0.92 1482.07 1.00 2902 423 104 21 FALSE 0.46
colorectal cancer KRAS_G12C DNMT3A 10 11 40-50yrs -5.97 -10.90 -0.47 3.58 1.33 431 10 11 0 TRUE 1.08
colorectal cancer KRAS_G12C DNMT3A 31 21 50-65yrs -5.98 -10.97 -0.48 3.57 1.33 916 31 21 0 TRUE 1.09
colorectal cancer KRAS_G12C DNMT3A 23 19 >65yrs -5.99 -10.96 -0.50 3.58 1.33 611 23 19 0 TRUE 1.09
non-small cell lung cancer KRAS_G12C DNMT3A 152 30 50-65yrs 0.57 -0.16 1.22 1330.20 1.00 1139 146 24 6 TRUE 1.08
non-small cell lung cancer KRAS_G12C DNMT3A 291 42 >65yrs 0.54 -0.10 1.14 1299.12 1.00 1805 282 33 9 TRUE 1.07
colorectal cancer KRAS_G12C DNMT3A 64 51 Age:overall -5.97 -10.89 -0.50 3.56 1.34 1958 64 51 0 TRUE 1.09
non-small cell lung cancer KRAS_G12C DNMT3A 443 72 Age:overall 0.56 -0.18 1.30 1399.70 1.00 2944 428 57 15 TRUE 0.87
colorectal cancer KRAS_G12C MSH6 6 12 <40yrs -5.21 -11.29 -0.97 713.34 1.00 200 6 12 0 TRUE 1.30
colorectal cancer KRAS_G12C MSH6 10 24 40-50yrs -5.20 -11.40 -0.92 748.21 1.00 421 10 24 0 TRUE 1.30
colorectal cancer KRAS_G12C MSH6 31 38 50-65yrs -5.21 -11.46 -1.00 704.87 1.00 908 31 38 0 TRUE 1.31
colorectal cancer KRAS_G12C MSH6 23 26 >65yrs -5.21 -11.33 -1.01 739.21 1.00 603 23 26 0 TRUE 1.31
colorectal cancer KRAS_G12C MSH6 70 100 Age:overall -5.21 -11.39 -1.02 709.56 1.00 2132 70 100 0 TRUE 1.31
non-small cell lung cancer KRAS_G12C MAX 152 15 50-65yrs 0.96 0.12 1.86 1500.28 1.00 1147 147 10 5 FALSE 1.53
non-small cell lung cancer KRAS_G12C MAX 292 39 >65yrs 0.76 0.05 1.44 1391.26 1.00 1800 283 30 9 FALSE 1.52
non-small cell lung cancer KRAS_G12C MAX 444 54 Age:overall 0.86 -0.14 1.88 1486.57 1.00 2947 430 40 14 FALSE 1.00
non-small cell lung cancer KRAS_G12C INPP4B 152 46 50-65yrs 0.65 0.11 1.19 776.93 1.00 1129 143 37 9 FALSE 1.77
non-small cell lung cancer KRAS_G12C INPP4B 293 76 >65yrs 0.68 0.22 1.17 662.36 1.00 1785 275 58 18 FALSE 2.36
non-small cell lung cancer KRAS_G12C INPP4B 445 122 Age:overall 0.66 0.02 1.25 790.80 1.00 2914 418 95 27 FALSE 1.11
non-small cell lung cancer KRAS_G12C NFE2L2 152 39 50-65yrs -0.62 -1.64 0.16 1207.47 1.00 1128 150 37 2 FALSE 0.75
non-small cell lung cancer KRAS_G12C NFE2L2 292 85 >65yrs -0.43 -1.14 0.18 1414.96 1.00 1771 283 76 9 FALSE 0.70
non-small cell lung cancer KRAS_G12C NFE2L2 444 124 Age:overall -0.52 -1.53 0.36 1289.32 1.00 2899 433 113 11 FALSE 0.55
colorectal cancer KRAS_G12C SOX9 6 22 <40yrs 0.02 -0.92 0.81 787.40 1.00 191 6 22 0 FALSE 0.02
colorectal cancer KRAS_G12C SOX9 10 41 40-50yrs 0.08 -0.80 0.86 872.77 1.00 402 8 39 2 FALSE 0.07
colorectal cancer KRAS_G12C SOX9 31 114 50-65yrs 0.02 -0.84 0.75 932.25 1.00 841 28 111 3 FALSE 0.02
colorectal cancer KRAS_G12C SOX9 25 87 >65yrs 0.08 -0.75 0.80 784.69 1.00 547 21 83 4 FALSE 0.08
colorectal cancer KRAS_G12C SOX9 72 264 Age:overall 0.05 -0.78 0.75 736.01 1.00 1981 63 255 9 FALSE 0.04
colorectal cancer KRAS_G12C ETV1 29 15 50-65yrs -4.55 -12.01 0.15 1008.82 1.01 897 29 15 0 TRUE 0.79
colorectal cancer KRAS_G12C ETV1 22 23 >65yrs -4.60 -11.95 -0.05 987.48 1.01 590 22 23 0 TRUE 0.85
colorectal cancer KRAS_G12C ETV1 51 38 Age:overall -4.46 -11.51 0.04 1001.79 1.01 1487 51 38 0 TRUE 0.84
colorectal cancer KRAS_G12C ARAF 31 22 50-65yrs -0.77 -3.52 1.21 1211.85 1.00 918 30 21 1 FALSE 0.28
colorectal cancer KRAS_G12C ARAF 23 23 >65yrs -1.09 -4.30 0.98 1282.22 1.00 605 23 23 0 FALSE 0.38
non-small cell lung cancer KRAS_G12C ARAF 152 26 50-65yrs -0.03 -0.91 0.74 1411.50 1.00 1144 149 23 3 FALSE 0.02
non-small cell lung cancer KRAS_G12C ARAF 292 42 >65yrs -0.01 -0.77 0.72 1220.01 1.00 1805 286 36 6 FALSE 0.01
colorectal cancer KRAS_G12C ARAF 54 45 Age:overall -0.92 -3.71 1.23 1266.45 1.00 1523 53 44 1 FALSE 0.33
non-small cell lung cancer KRAS_G12C ARAF 444 68 Age:overall -0.02 -0.96 0.74 1260.68 1.00 2949 435 59 9 FALSE 0.02
non-small cell lung cancer KRAS_G12C JAK2 159 38 50-65yrs -0.33 -1.26 0.53 1445.11 1.00 1183 155 34 4 TRUE 0.32
non-small cell lung cancer KRAS_G12C JAK2 300 35 >65yrs -0.48 -1.43 0.35 1315.42 1.00 1851 297 32 3 TRUE 0.51
non-small cell lung cancer KRAS_G12C JAK2 459 73 Age:overall -0.41 -1.50 0.62 1407.88 1.00 3034 452 66 7 TRUE 0.33
colorectal cancer KRAS_G12C SMAD2 10 33 40-50yrs 0.90 -0.10 2.09 81.69 1.03 417 7 30 3 TRUE 0.87
colorectal cancer KRAS_G12C SMAD2 31 39 50-65yrs 0.62 -0.47 1.67 304.81 1.02 903 29 37 2 TRUE 0.62
colorectal cancer KRAS_G12C SMAD2 23 20 >65yrs 0.60 -0.65 1.80 604.80 1.01 607 22 19 1 TRUE 0.51
colorectal cancer KRAS_G12C SMAD2 64 92 Age:overall 0.71 -0.38 1.76 247.46 1.02 1927 58 86 6 TRUE 0.70
non-small cell lung cancer KRAS_G12C TP63 152 31 50-65yrs -0.64 -2.08 0.34 1170.01 1.00 1128 151 30 1 FALSE 0.54
non-small cell lung cancer KRAS_G12C TP63 291 38 >65yrs -0.24 -1.19 0.56 685.94 1.00 1799 285 32 6 FALSE 0.22
non-small cell lung cancer KRAS_G12C TP63 443 69 Age:overall -0.45 -1.75 0.65 930.98 1.00 2927 436 62 7 FALSE 0.31
colorectal cancer KRAS_G12C JUN 10 11 40-50yrs -4.58 -11.46 -0.28 449.26 1.00 416 10 11 0 FALSE 0.89
colorectal cancer KRAS_G12C JUN 29 18 50-65yrs -4.57 -11.46 -0.24 467.36 1.00 893 29 18 0 FALSE 0.89
colorectal cancer KRAS_G12C JUN 22 19 >65yrs -4.57 -11.41 -0.28 455.24 1.00 594 22 19 0 FALSE 0.89
colorectal cancer KRAS_G12C JUN 61 48 Age:overall -4.56 -11.41 -0.31 458.83 1.00 1903 61 48 0 FALSE 0.89
colorectal cancer KRAS_G12C DNMT3B 29 28 50-65yrs -4.57 -11.45 -0.26 534.56 1.01 883 29 28 0 FALSE 0.91
colorectal cancer KRAS_G12C DNMT3B 22 15 >65yrs -4.56 -11.30 -0.24 546.38 1.01 597 22 15 0 FALSE 0.90
colorectal cancer KRAS_G12C DNMT3B 56 55 Age:overall -4.54 -11.22 -0.27 539.35 1.01 1678 56 55 0 FALSE 0.92
non-small cell lung cancer KRAS_G12C MYOD1 152 21 50-65yrs 0.13 -0.85 1.08 962.05 1.00 1144 148 17 4 FALSE 0.10
non-small cell lung cancer KRAS_G12C MYOD1 291 31 >65yrs -0.10 -1.15 0.77 540.03 1.00 1802 288 28 3 FALSE 0.07
non-small cell lung cancer KRAS_G12C MYOD1 443 52 Age:overall 0.02 -1.10 1.09 799.28 1.00 2946 436 45 7 FALSE 0.01
colorectal cancer KRAS_G12C FGFR1 10 12 40-50yrs -4.42 -11.44 -0.15 481.06 1.00 463 10 12 0 TRUE 0.94
colorectal cancer KRAS_G12C FGFR1 39 21 50-65yrs -4.44 -11.47 -0.35 484.90 1.00 1017 39 21 0 TRUE 0.95
colorectal cancer KRAS_G12C FGFR1 25 11 >65yrs -4.44 -11.52 -0.34 487.80 1.00 686 25 11 0 TRUE 0.95
colorectal cancer KRAS_G12C FGFR1 74 44 Age:overall -4.42 -11.39 -0.34 470.91 1.00 2166 74 44 0 TRUE 0.95
colorectal cancer KRAS_G12C MITF 31 25 50-65yrs 0.87 -0.58 2.08 954.72 1.00 915 28 22 3 FALSE 0.69
colorectal cancer KRAS_G12C MITF 23 14 >65yrs 0.29 -2.93 1.76 912.58 1.00 612 23 14 0 FALSE 0.09
colorectal cancer KRAS_G12C MITF 54 39 Age:overall 0.57 -1.55 2.04 907.99 1.00 1527 51 36 3 FALSE 0.27
non-small cell lung cancer KRAS_G12C BTK 152 28 50-65yrs 0.29 -0.54 1.12 1354.99 1.00 1139 148 24 4 TRUE 0.31
non-small cell lung cancer KRAS_G12C BTK 291 29 >65yrs 0.36 -0.46 1.09 1100.81 1.00 1815 285 23 6 TRUE 0.44
non-small cell lung cancer KRAS_G12C BTK 443 57 Age:overall 0.32 -0.66 1.36 1381.75 1.00 2954 433 47 10 TRUE 0.26
colorectal cancer KRAS_G12C SH2B3 29 25 50-65yrs -4.50 -12.04 -0.24 291.10 1.01 831 29 25 0 FALSE 0.82
colorectal cancer KRAS_G12C SH2B3 20 19 >65yrs -4.49 -12.01 -0.18 281.69 1.01 556 20 19 0 FALSE 0.83
colorectal cancer KRAS_G12C SH2B3 49 44 Age:overall -4.44 -11.93 -0.09 291.93 1.01 1387 49 44 0 FALSE 0.82
colorectal cancer KRAS_G12C GLI1 8 17 40-50yrs -4.87 -11.50 -0.62 960.63 1.00 391 8 17 0 FALSE 1.08
colorectal cancer KRAS_G12C GLI1 29 36 50-65yrs -4.87 -11.50 -0.61 949.33 1.00 819 29 36 0 FALSE 1.08
colorectal cancer KRAS_G12C GLI1 20 25 >65yrs -4.86 -11.54 -0.65 953.22 1.00 551 20 25 0 FALSE 1.08
non-small cell lung cancer KRAS_G12C GLI1 134 35 50-65yrs 0.57 -0.06 1.17 1317.42 1.00 999 128 29 6 FALSE 1.16
non-small cell lung cancer KRAS_G12C GLI1 277 64 >65yrs 0.66 0.15 1.18 1245.69 1.00 1642 261 48 16 FALSE 1.91
colorectal cancer KRAS_G12C GLI1 57 78 Age:overall -4.86 -11.44 -0.73 961.17 1.00 1761 57 78 0 FALSE 1.08
non-small cell lung cancer KRAS_G12C GLI1 411 99 Age:overall 0.62 -0.04 1.24 1412.43 1.00 2641 389 77 22 FALSE 1.06
colorectal cancer KRAS_G12C ZFHX3 6 28 <40yrs -2.55 -5.27 -0.52 259.12 1.02 175 6 28 0 FALSE 1.36
colorectal cancer KRAS_G12C ZFHX3 8 32 40-50yrs -2.53 -5.22 -0.53 245.43 1.02 379 8 32 0 FALSE 1.36
colorectal cancer KRAS_G12C ZFHX3 29 82 50-65yrs -2.55 -5.23 -0.57 294.05 1.02 794 29 82 0 FALSE 1.40
colorectal cancer KRAS_G12C ZFHX3 20 84 >65yrs -2.46 -5.07 -0.56 228.48 1.02 519 19 83 1 FALSE 1.36
non-small cell lung cancer KRAS_G12C ZFHX3 133 57 50-65yrs -0.04 -0.74 0.62 1075.76 1.00 980 125 49 8 FALSE 0.05
non-small cell lung cancer KRAS_G12C ZFHX3 277 96 >65yrs -0.23 -0.85 0.32 1393.59 1.00 1603 267 86 10 FALSE 0.36
colorectal cancer KRAS_G12C ZFHX3 63 226 Age:overall -2.52 -5.14 -0.69 235.61 1.02 1867 62 225 1 FALSE 1.40
non-small cell lung cancer KRAS_G12C ZFHX3 410 153 Age:overall -0.14 -0.88 0.62 1496.10 1.00 2583 392 135 18 FALSE 0.14
colorectal cancer KRAS_G12C MST1R 27 26 50-65yrs -4.66 -11.37 -0.16 987.13 1.00 802 27 26 0 FALSE 0.91
colorectal cancer KRAS_G12C MST1R 19 33 >65yrs -4.66 -11.29 -0.50 952.90 1.00 534 19 33 0 FALSE 0.93
colorectal cancer KRAS_G12C MST1R 46 59 Age:overall -4.56 -11.04 -0.40 991.17 1.00 1336 46 59 0 FALSE 0.92
colorectal cancer KRAS_G12C MGA 6 18 <40yrs -1.03 -3.01 0.46 472.07 1.00 183 6 18 0 FALSE 0.61
colorectal cancer KRAS_G12C MGA 8 19 40-50yrs -1.04 -2.87 0.52 489.46 1.01 389 8 19 0 FALSE 0.62
colorectal cancer KRAS_G12C MGA 29 41 50-65yrs -0.98 -2.78 0.47 463.11 1.01 813 28 40 1 FALSE 0.60
colorectal cancer KRAS_G12C MGA 20 45 >65yrs -0.98 -2.71 0.48 348.08 1.01 534 19 44 1 FALSE 0.61
non-small cell lung cancer KRAS_G12C MGA 134 60 50-65yrs 0.40 -0.16 0.91 1489.07 1.00 979 124 50 10 FALSE 0.86
non-small cell lung cancer KRAS_G12C MGA 278 129 >65yrs 0.42 0.00 0.83 1304.66 1.00 1599 253 104 25 FALSE 1.30
colorectal cancer KRAS_G12C MGA 63 123 Age:overall -1.01 -2.75 0.44 410.93 1.01 1919 61 121 2 FALSE 0.64
non-small cell lung cancer KRAS_G12C MGA 412 189 Age:overall 0.42 -0.22 1.05 1646.38 1.00 2578 377 154 35 FALSE 0.62
colorectal cancer KRAS_G12C TCF3 8 12 40-50yrs -4.73 -11.52 -0.39 1411.19 1.00 380 8 12 0 FALSE 0.97
colorectal cancer KRAS_G12C TCF3 27 26 50-65yrs -4.74 -11.73 -0.41 1407.78 1.00 802 27 26 0 FALSE 0.97
colorectal cancer KRAS_G12C TCF3 19 22 >65yrs -4.72 -11.79 -0.44 1408.98 1.00 538 19 22 0 FALSE 0.97
colorectal cancer KRAS_G12C TCF3 54 60 Age:overall -4.72 -11.59 -0.45 1420.59 1.00 1720 54 60 0 FALSE 0.98
non-small cell lung cancer KRAS_G12C KMT2B 75 22 50-65yrs 0.31 -0.62 1.32 1306.68 1.00 573 70 17 5 FALSE 0.28
non-small cell lung cancer KRAS_G12C KMT2B 158 47 >65yrs -0.06 -0.95 0.70 844.30 1.00 930 153 42 5 FALSE 0.05
non-small cell lung cancer KRAS_G12C KMT2B 233 69 Age:overall 0.11 -1.10 1.24 1468.61 1.00 1503 223 59 10 FALSE 0.07
colorectal cancer KRAS_G12C TCF7L2 6 34 <40yrs -0.04 -0.92 0.60 34.62 1.07 164 6 34 0 FALSE 0.03
colorectal cancer KRAS_G12C TCF7L2 8 56 40-50yrs 0.04 -0.77 0.77 60.46 1.05 356 5 53 3 FALSE 0.03
colorectal cancer KRAS_G12C TCF7L2 29 121 50-65yrs -0.08 -0.98 0.56 29.89 1.09 745 28 120 1 FALSE 0.07
colorectal cancer KRAS_G12C TCF7L2 20 88 >65yrs 0.06 -0.73 0.74 49.18 1.05 496 15 83 5 FALSE 0.05
colorectal cancer KRAS_G12C TCF7L2 63 299 Age:overall -0.01 -0.79 0.63 36.88 1.07 1761 54 290 9 FALSE 0.01
colorectal cancer KRAS_G12C ANKRD11 8 14 40-50yrs -5.20 -11.68 -0.82 705.58 1.00 379 8 14 0 FALSE 1.11
colorectal cancer KRAS_G12C ANKRD11 27 61 50-65yrs -5.20 -11.74 -0.91 664.38 1.00 784 27 61 0 FALSE 1.13
colorectal cancer KRAS_G12C ANKRD11 19 50 >65yrs -5.24 -11.66 -0.98 684.23 1.00 516 19 50 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C ANKRD11 133 21 50-65yrs -0.31 -1.40 0.57 1539.03 1.00 1002 131 19 2 FALSE 0.27
non-small cell lung cancer KRAS_G12C ANKRD11 276 50 >65yrs -0.26 -1.11 0.50 1366.49 1.00 1639 270 44 6 FALSE 0.28
colorectal cancer KRAS_G12C ANKRD11 59 146 Age:overall -5.20 -11.47 -0.92 662.29 1.00 1852 59 146 0 FALSE 1.14
non-small cell lung cancer KRAS_G12C ANKRD11 409 71 Age:overall -0.28 -1.36 0.66 1227.79 1.00 2641 401 63 8 FALSE 0.21
colorectal cancer KRAS_G12C PGR 27 24 50-65yrs -5.11 -11.09 -0.40 91.21 1.06 804 27 24 0 FALSE 1.10
colorectal cancer KRAS_G12C PGR 19 24 >65yrs -5.09 -11.11 -0.40 84.19 1.07 535 19 24 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C PGR 133 35 50-65yrs 0.14 -1.11 1.00 1364.06 1.00 991 130 32 3 FALSE 0.10
non-small cell lung cancer KRAS_G12C PGR 277 49 >65yrs 0.80 0.14 1.44 1507.95 1.00 1645 262 34 15 FALSE 1.79
colorectal cancer KRAS_G12C PGR 46 48 Age:overall -5.07 -10.95 -0.47 82.64 1.07 1339 46 48 0 FALSE 1.10
non-small cell lung cancer KRAS_G12C PGR 410 84 Age:overall 0.47 -0.85 1.50 1454.45 1.00 2636 392 66 18 FALSE 0.35
colorectal cancer KRAS_G12C PLCG2 8 14 40-50yrs -0.48 -2.65 1.19 1226.67 1.00 378 8 14 0 FALSE 0.20
colorectal cancer KRAS_G12C PLCG2 27 27 50-65yrs -0.19 -1.92 1.29 987.97 1.00 804 25 25 2 FALSE 0.09
colorectal cancer KRAS_G12C PLCG2 19 35 >65yrs -0.61 -2.80 0.88 1122.14 1.00 526 19 35 0 FALSE 0.29
non-small cell lung cancer KRAS_G12C PLCG2 133 13 50-65yrs -0.22 -1.70 0.87 1614.33 1.00 1010 132 12 1 FALSE 0.13
non-small cell lung cancer KRAS_G12C PLCG2 276 43 >65yrs 0.06 -0.82 0.79 1546.87 1.00 1648 269 36 7 FALSE 0.05
colorectal cancer KRAS_G12C PLCG2 54 76 Age:overall -0.42 -2.25 1.04 1109.90 1.00 1708 52 74 2 FALSE 0.21
non-small cell lung cancer KRAS_G12C PLCG2 409 56 Age:overall -0.09 -1.49 1.01 1470.95 1.00 2658 401 48 8 FALSE 0.05
colorectal cancer KRAS_G12C POLD1 6 12 <40yrs -1.71 -4.46 0.23 1008.53 1.00 186 6 12 0 TRUE 0.77
colorectal cancer KRAS_G12C POLD1 8 16 40-50yrs -1.69 -4.48 0.23 914.67 1.00 391 8 16 0 TRUE 0.77
colorectal cancer KRAS_G12C POLD1 29 39 50-65yrs -1.73 -4.54 0.16 969.40 1.00 821 29 39 0 TRUE 0.81
colorectal cancer KRAS_G12C POLD1 20 45 >65yrs -1.62 -4.33 0.19 983.03 1.00 542 19 44 1 TRUE 0.75
non-small cell lung cancer KRAS_G12C POLD1 133 23 50-65yrs -0.88 -2.39 0.19 1357.91 1.00 1005 132 22 1 TRUE 0.75
non-small cell lung cancer KRAS_G12C POLD1 276 32 >65yrs -0.76 -2.05 0.24 1256.31 1.00 1657 273 29 3 TRUE 0.75
colorectal cancer KRAS_G12C POLD1 63 112 Age:overall -1.69 -4.43 0.17 963.43 1.00 1940 62 111 1 TRUE 0.80
non-small cell lung cancer KRAS_G12C POLD1 409 55 Age:overall -0.83 -2.29 0.28 1347.97 1.00 2662 405 51 4 TRUE 0.70
colorectal cancer KRAS_G12C INHBA 29 26 50-65yrs -0.75 -3.44 1.37 203.79 1.01 829 28 25 1 FALSE 0.27
colorectal cancer KRAS_G12C INHBA 20 19 >65yrs -0.96 -3.88 1.34 173.51 1.02 555 20 19 0 FALSE 0.32
non-small cell lung cancer KRAS_G12C INHBA 133 29 50-65yrs 0.28 -0.46 1.13 288.61 1.01 1004 127 23 6 FALSE 0.32
non-small cell lung cancer KRAS_G12C INHBA 276 55 >65yrs 0.06 -0.65 0.70 1475.59 1.00 1644 269 48 7 FALSE 0.06
colorectal cancer KRAS_G12C INHBA 49 45 Age:overall -0.84 -3.66 1.41 194.09 1.01 1384 48 44 1 FALSE 0.29
non-small cell lung cancer KRAS_G12C INHBA 409 84 Age:overall 0.15 -0.67 1.01 1331.66 1.00 2648 396 71 13 FALSE 0.14
non-small cell lung cancer KRAS_G12C PREX2 75 41 50-65yrs 0.44 -0.20 1.08 357.36 1.01 557 68 34 7 FALSE 0.74
non-small cell lung cancer KRAS_G12C PREX2 159 63 >65yrs 0.41 -0.17 0.97 381.72 1.01 925 147 51 12 FALSE 0.79
non-small cell lung cancer KRAS_G12C PREX2 234 104 Age:overall 0.42 -0.30 1.09 459.58 1.01 1482 215 85 19 FALSE 0.58
colorectal cancer KRAS_G12C AMER1 6 13 <40yrs 0.02 -1.28 1.11 1405.86 1.00 201 6 13 0 FALSE 0.01
colorectal cancer KRAS_G12C AMER1 10 33 40-50yrs 0.08 -1.09 1.13 1231.81 1.00 410 9 32 1 FALSE 0.05
colorectal cancer KRAS_G12C AMER1 31 53 50-65yrs 0.15 -1.00 1.14 1272.83 1.00 889 28 50 3 FALSE 0.11
colorectal cancer KRAS_G12C AMER1 23 70 >65yrs 0.03 -1.10 0.99 1360.06 1.00 564 21 68 2 FALSE 0.02
non-small cell lung cancer KRAS_G12C AMER1 152 48 50-65yrs 0.67 0.11 1.16 1100.24 1.00 1128 143 39 9 FALSE 1.92
non-small cell lung cancer KRAS_G12C AMER1 293 93 >65yrs 0.74 0.30 1.15 678.59 1.00 1780 270 70 23 FALSE 3.00
colorectal cancer KRAS_G12C AMER1 70 169 Age:overall 0.07 -1.02 1.04 1277.21 1.00 2064 64 163 6 FALSE 0.05
non-small cell lung cancer KRAS_G12C AMER1 445 141 Age:overall 0.69 0.04 1.25 1125.65 1.00 2908 413 109 32 FALSE 1.36
colorectal cancer KRAS_G12C HLA-A 27 17 50-65yrs -4.85 -13.90 -0.15 109.89 1.00 811 27 17 0 FALSE 0.84
colorectal cancer KRAS_G12C HLA-A 19 20 >65yrs -4.86 -13.99 -0.08 109.72 1.00 540 19 20 0 FALSE 0.85
colorectal cancer KRAS_G12C HLA-A 46 37 Age:overall -4.80 -13.80 -0.26 109.13 1.00 1351 46 37 0 FALSE 0.85
colorectal cancer KRAS_G12C EPHA7 8 13 40-50yrs -4.41 -10.67 -0.27 10.43 1.31 392 8 13 0 FALSE 1.00
colorectal cancer KRAS_G12C EPHA7 29 39 50-65yrs -4.43 -10.81 -0.25 10.33 1.31 819 29 39 0 FALSE 0.99
colorectal cancer KRAS_G12C EPHA7 20 30 >65yrs -4.42 -10.64 -0.28 10.39 1.32 547 20 30 0 FALSE 1.01
non-small cell lung cancer KRAS_G12C EPHA7 133 48 50-65yrs 0.18 -0.47 0.74 1455.40 1.00 990 126 41 7 FALSE 0.25
non-small cell lung cancer KRAS_G12C EPHA7 276 77 >65yrs 0.15 -0.39 0.66 1350.55 1.00 1623 264 65 12 FALSE 0.24
colorectal cancer KRAS_G12C EPHA7 57 82 Age:overall -4.41 -10.73 -0.26 10.49 1.31 1758 57 82 0 FALSE 1.01
non-small cell lung cancer KRAS_G12C EPHA7 409 125 Age:overall 0.17 -0.54 0.80 1373.70 1.00 2613 390 106 19 FALSE 0.21
colorectal cancer KRAS_G12C NCOA3 29 19 50-65yrs -1.27 -4.88 0.99 1023.79 1.00 836 29 19 0 TRUE 0.37
colorectal cancer KRAS_G12C NCOA3 20 23 >65yrs -0.80 -3.53 1.19 675.95 1.00 553 19 22 1 TRUE 0.29
colorectal cancer KRAS_G12C NCOA3 49 42 Age:overall -1.00 -4.09 1.22 1044.89 1.00 1389 48 41 1 TRUE 0.33
non-small cell lung cancer KRAS_G12C DROSHA 75 17 50-65yrs 0.18 -0.68 1.08 801.16 1.01 568 72 14 3 FALSE 0.19
non-small cell lung cancer KRAS_G12C DROSHA 158 34 >65yrs 0.13 -0.71 0.81 1431.12 1.00 934 153 29 5 FALSE 0.16
non-small cell lung cancer KRAS_G12C DROSHA 233 51 Age:overall 0.17 -0.76 1.03 1397.67 1.00 1502 225 43 8 FALSE 0.16
cancer of unknown primary KRAS_G12D SPEN 21 11 50-65yrs 0.46 -1.20 1.93 1462.48 1.00 283 19 9 2 FALSE 0.25
cancer of unknown primary KRAS_G12D SPEN 27 38 >65yrs -0.15 -1.71 0.96 225.05 1.01 309 25 36 2 FALSE 0.09
colorectal cancer KRAS_G12D SPEN 35 23 <40yrs -0.03 -0.74 0.66 1455.03 1.00 171 32 20 3 FALSE 0.03
colorectal cancer KRAS_G12D SPEN 56 25 40-50yrs 0.16 -0.53 0.88 1490.57 1.00 380 50 19 6 FALSE 0.19
colorectal cancer KRAS_G12D SPEN 127 45 50-65yrs -0.10 -0.78 0.50 1259.20 1.01 810 122 40 5 FALSE 0.12
colorectal cancer KRAS_G12D SPEN 85 62 >65yrs -0.11 -0.79 0.45 858.89 1.00 526 79 56 6 FALSE 0.14
non-small cell lung cancer KRAS_G12D SPEN 41 67 50-65yrs -1.11 -3.08 0.45 1401.47 1.00 1232 40 66 1 FALSE 0.65
non-small cell lung cancer KRAS_G12D SPEN 100 49 >65yrs -1.16 -3.18 0.36 1372.38 1.00 1988 99 48 1 FALSE 0.71
uterine cancer KRAS_G12D SPEN 12 19 40-50yrs 1.25 0.16 2.41 1417.35 1.00 73 6 13 6 FALSE 1.42
uterine cancer KRAS_G12D SPEN 26 54 50-65yrs 0.45 -0.67 1.40 1336.18 1.00 459 22 50 4 FALSE 0.42
uterine cancer KRAS_G12D SPEN 18 44 >65yrs -0.38 -2.77 1.00 1391.51 1.00 426 18 44 0 FALSE 0.16
cancer of unknown primary KRAS_G12D SPEN 48 49 Age:overall 0.15 -1.72 2.09 1383.18 1.00 592 44 45 4 FALSE 0.06
colorectal cancer KRAS_G12D SPEN 303 155 Age:overall -0.02 -0.62 0.55 1585.70 1.00 1887 283 135 20 FALSE 0.02
non-small cell lung cancer KRAS_G12D SPEN 141 116 Age:overall -1.14 -3.35 0.61 1445.94 1.00 3220 139 114 2 FALSE 0.60
uterine cancer KRAS_G12D SPEN 56 117 Age:overall 0.41 -1.01 1.59 1445.09 1.00 958 46 107 10 FALSE 0.26
colorectal cancer KRAS_G12D KMT2C 35 25 <40yrs -0.20 -0.83 0.41 514.24 1.00 164 31 21 4 FALSE 0.29
colorectal cancer KRAS_G12D KMT2C 54 39 40-50yrs -0.29 -0.88 0.25 692.46 1.00 361 51 36 3 FALSE 0.46
colorectal cancer KRAS_G12D KMT2C 125 65 50-65yrs -0.15 -0.76 0.40 408.11 1.01 775 114 54 11 FALSE 0.22
colorectal cancer KRAS_G12D KMT2C 81 69 >65yrs -0.35 -1.00 0.17 856.95 1.00 504 77 65 4 FALSE 0.60
non-small cell lung cancer KRAS_G12D KMT2C 41 90 50-65yrs -0.79 -2.15 0.21 1363.31 1.00 1190 40 89 1 FALSE 0.72
non-small cell lung cancer KRAS_G12D KMT2C 100 122 >65yrs -0.60 -1.69 0.30 1215.56 1.00 1909 96 118 4 FALSE 0.66
colorectal cancer KRAS_G12D KMT2C 295 198 Age:overall -0.25 -0.81 0.25 524.75 1.01 1804 273 176 22 FALSE 0.45
non-small cell lung cancer KRAS_G12D KMT2C 141 212 Age:overall -0.69 -2.02 0.36 1467.35 1.00 3099 136 207 5 FALSE 0.58
appendiceal cancer KRAS_G12D TP53 21 20 50-65yrs 0.60 -0.36 1.47 1325.50 1.00 47 14 13 7 TRUE 0.70
appendiceal cancer KRAS_G12D TP53 15 14 >65yrs 0.66 -0.34 1.68 1387.08 1.00 24 9 8 6 TRUE 0.71
cancer of unknown primary KRAS_G12D TP53 22 154 50-65yrs 0.47 -0.30 1.27 1422.09 1.00 168 8 140 14 TRUE 0.63
cancer of unknown primary KRAS_G12D TP53 26 218 >65yrs -0.35 -1.12 0.42 1448.62 1.00 153 16 208 10 TRUE 0.43
colorectal cancer KRAS_G12D TP53 39 165 <40yrs -0.46 -0.74 -0.15 1386.44 1.00 66 16 142 23 TRUE 2.62
colorectal cancer KRAS_G12D TP53 65 350 40-50yrs -0.50 -0.79 -0.23 1352.69 1.00 125 27 312 38 TRUE 3.20
colorectal cancer KRAS_G12D TP53 156 724 50-65yrs -0.51 -0.77 -0.26 1193.63 1.00 322 75 643 81 TRUE 4.08
colorectal cancer KRAS_G12D TP53 103 480 >65yrs -0.47 -0.72 -0.20 1201.22 1.00 244 45 422 58 TRUE 3.26
non-small cell lung cancer KRAS_G12D TP53 8 102 40-50yrs -1.04 -1.70 -0.46 1474.20 1.00 97 6 100 2 TRUE 2.98
non-small cell lung cancer KRAS_G12D TP53 42 814 50-65yrs -1.07 -1.54 -0.61 1651.72 1.00 590 29 801 13 TRUE 5.08
non-small cell lung cancer KRAS_G12D TP53 104 1113 >65yrs -0.93 -1.34 -0.54 1581.62 1.00 1078 73 1082 31 TRUE 5.30
pancreatic cancer KRAS_G12D TP53 40 60 40-50yrs 0.91 0.49 1.48 948.91 1.00 54 12 32 28 TRUE 3.73
pancreatic cancer KRAS_G12D TP53 207 384 50-65yrs 0.87 0.58 1.17 1243.61 1.00 200 54 231 153 TRUE 8.59
pancreatic cancer KRAS_G12D TP53 260 495 >65yrs 0.80 0.52 1.07 1318.54 1.00 221 69 304 191 TRUE 7.81
uterine cancer KRAS_G12D TP53 9 28 40-50yrs -1.19 -2.46 -0.04 1357.44 1.00 60 8 27 1 TRUE 1.29
uterine cancer KRAS_G12D TP53 27 226 50-65yrs -1.16 -2.04 -0.37 1434.74 1.00 349 22 221 5 TRUE 2.12
uterine cancer KRAS_G12D TP53 19 285 >65yrs -1.20 -2.13 -0.39 1403.82 1.00 248 14 280 5 TRUE 2.24
appendiceal cancer KRAS_G12D TP53 36 34 Age:overall 0.63 -0.47 1.69 1422.14 1.00 71 23 21 13 TRUE 0.57
cancer of unknown primary KRAS_G12D TP53 55 420 Age:overall 0.16 -0.69 1.18 1466.68 1.00 413 27 392 28 TRUE 0.13
colorectal cancer KRAS_G12D TP53 363 1719 Age:overall -0.48 -0.72 -0.24 1278.10 1.00 757 163 1519 200 TRUE 3.76
non-small cell lung cancer KRAS_G12D TP53 157 2056 Age:overall -1.03 -1.55 -0.56 1438.86 1.00 1800 111 2010 46 TRUE 4.49
pancreatic cancer KRAS_G12D TP53 507 939 Age:overall 0.86 0.47 1.25 1271.13 1.00 475 135 567 372 TRUE 4.80
uterine cancer KRAS_G12D TP53 55 539 Age:overall -1.18 -2.18 -0.24 1403.79 1.00 657 44 528 11 TRUE 1.88
colorectal cancer KRAS_G12D ATRX 56 31 40-50yrs -0.33 -1.23 0.48 1435.61 1.00 374 53 28 3 TRUE 0.35
colorectal cancer KRAS_G12D ATRX 127 31 50-65yrs -0.19 -1.02 0.59 1472.21 1.00 816 122 26 5 TRUE 0.18
colorectal cancer KRAS_G12D ATRX 84 48 >65yrs -0.49 -1.46 0.26 1485.36 1.00 529 81 45 3 TRUE 0.59
non-small cell lung cancer KRAS_G12D ATRX 41 74 50-65yrs 0.07 -0.94 0.89 1500.34 1.00 1212 39 72 2 TRUE 0.05
non-small cell lung cancer KRAS_G12D ATRX 100 123 >65yrs 0.23 -0.51 0.90 1372.78 1.00 1931 92 115 8 TRUE 0.28
uterine cancer KRAS_G12D ATRX 9 26 40-50yrs -1.33 -3.00 0.08 1391.64 1.00 68 8 25 1 TRUE 1.00
uterine cancer KRAS_G12D ATRX 25 96 50-65yrs -1.30 -2.77 -0.11 1412.98 1.00 436 23 94 2 TRUE 1.18
uterine cancer KRAS_G12D ATRX 18 43 >65yrs -1.66 -3.68 -0.06 1369.14 1.00 432 18 43 0 TRUE 1.17
colorectal cancer KRAS_G12D ATRX 267 110 Age:overall -0.34 -1.29 0.46 1429.89 1.00 1719 256 99 11 TRUE 0.36
non-small cell lung cancer KRAS_G12D ATRX 141 197 Age:overall 0.15 -0.94 1.14 1451.03 1.00 3143 131 187 10 TRUE 0.11
uterine cancer KRAS_G12D ATRX 53 176 Age:overall -1.46 -2.98 -0.14 1123.29 1.00 963 50 173 3 TRUE 1.30
colorectal cancer KRAS_G12D ATR 35 17 <40yrs -0.43 -1.12 0.22 166.45 1.02 171 34 16 1 FALSE 0.63
colorectal cancer KRAS_G12D ATR 56 22 40-50yrs -0.43 -1.17 0.23 156.33 1.02 383 55 21 1 FALSE 0.64
colorectal cancer KRAS_G12D ATR 129 48 50-65yrs -0.40 -1.09 0.22 129.88 1.03 808 124 43 5 FALSE 0.64
colorectal cancer KRAS_G12D ATR 84 27 >65yrs -0.39 -1.08 0.23 132.75 1.02 545 80 23 4 FALSE 0.58
non-small cell lung cancer KRAS_G12D ATR 41 50 50-65yrs -0.27 -1.58 0.95 1162.97 1.00 1229 39 48 2 FALSE 0.17
non-small cell lung cancer KRAS_G12D ATR 100 73 >65yrs -0.45 -1.71 0.57 1161.16 1.00 1958 98 71 2 FALSE 0.36
uterine cancer KRAS_G12D ATR 25 55 50-65yrs -0.98 -3.10 0.50 1154.56 1.00 455 24 54 1 FALSE 0.56
uterine cancer KRAS_G12D ATR 18 25 >65yrs -0.72 -2.74 0.91 1264.46 1.00 439 17 24 1 FALSE 0.35
colorectal cancer KRAS_G12D ATR 304 114 Age:overall -0.41 -1.06 0.20 130.94 1.02 1907 293 103 11 FALSE 0.66
non-small cell lung cancer KRAS_G12D ATR 141 123 Age:overall -0.37 -1.76 0.80 1225.70 1.00 3187 137 119 4 FALSE 0.24
uterine cancer KRAS_G12D ATR 43 80 Age:overall -0.85 -3.11 0.90 1294.34 1.00 894 41 78 2 FALSE 0.40
colorectal cancer KRAS_G12D PDGFRA 38 12 <40yrs 0.01 -0.86 0.82 1116.49 1.00 190 37 11 1 TRUE 0.01
colorectal cancer KRAS_G12D PDGFRA 63 14 40-50yrs 0.00 -0.84 0.77 1033.69 1.00 408 62 13 1 TRUE 0.00
colorectal cancer KRAS_G12D PDGFRA 147 22 50-65yrs 0.04 -0.73 0.80 1082.78 1.00 911 143 18 4 TRUE 0.04
colorectal cancer KRAS_G12D PDGFRA 95 12 >65yrs 0.06 -0.73 0.83 1165.66 1.00 617 92 9 3 TRUE 0.06
non-small cell lung cancer KRAS_G12D PDGFRA 42 57 50-65yrs -0.92 -2.55 0.33 1292.99 1.00 1279 41 56 1 TRUE 0.67
non-small cell lung cancer KRAS_G12D PDGFRA 104 86 >65yrs -0.93 -2.40 0.25 1122.33 1.00 2000 102 84 2 TRUE 0.79
colorectal cancer KRAS_G12D PDGFRA 343 60 Age:overall 0.03 -0.71 0.78 1114.13 1.00 2126 334 51 9 TRUE 0.03
non-small cell lung cancer KRAS_G12D PDGFRA 146 143 Age:overall -0.91 -2.56 0.40 1120.91 1.00 3279 143 140 3 TRUE 0.62
colorectal cancer KRAS_G12D FBXW7 39 28 <40yrs 0.31 -0.08 0.67 536.53 1.00 177 33 22 6 TRUE 1.01
colorectal cancer KRAS_G12D FBXW7 65 60 40-50yrs 0.30 -0.07 0.63 470.17 1.00 377 55 50 10 TRUE 1.01
colorectal cancer KRAS_G12D FBXW7 154 144 50-65yrs 0.33 -0.01 0.66 488.73 1.00 823 125 115 29 TRUE 1.26
colorectal cancer KRAS_G12D FBXW7 98 107 >65yrs 0.29 -0.08 0.62 514.47 1.00 546 84 93 14 TRUE 0.94
non-small cell lung cancer KRAS_G12D FBXW7 42 32 50-65yrs -0.75 -2.88 0.86 1447.49 1.00 1302 41 31 1 TRUE 0.38
non-small cell lung cancer KRAS_G12D FBXW7 104 51 >65yrs -0.92 -3.08 0.54 1295.61 1.00 2034 103 50 1 TRUE 0.52
uterine cancer KRAS_G12D FBXW7 11 13 40-50yrs 1.08 -0.11 2.18 1420.85 1.00 78 7 9 4 TRUE 1.19
uterine cancer KRAS_G12D FBXW7 26 60 50-65yrs 0.96 0.08 1.82 1430.44 1.00 506 19 53 7 TRUE 1.54
uterine cancer KRAS_G12D FBXW7 19 70 >65yrs 0.07 -1.44 1.14 1405.52 1.00 434 18 69 1 TRUE 0.04
colorectal cancer KRAS_G12D FBXW7 356 339 Age:overall 0.31 -0.03 0.63 442.75 1.00 1923 297 280 59 TRUE 1.13
non-small cell lung cancer KRAS_G12D FBXW7 146 83 Age:overall -0.81 -2.94 0.78 1365.43 1.00 3336 144 81 2 TRUE 0.41
uterine cancer KRAS_G12D FBXW7 56 143 Age:overall 0.70 -0.51 1.76 1443.45 1.00 1018 44 131 12 TRUE 0.66
colorectal cancer KRAS_G12D MAP3K1 56 24 40-50yrs -0.52 -1.45 0.27 1367.04 1.00 378 53 21 3 FALSE 0.64
colorectal cancer KRAS_G12D MAP3K1 127 34 50-65yrs -0.55 -1.46 0.18 1323.23 1.00 811 124 31 3 FALSE 0.71
colorectal cancer KRAS_G12D MAP3K1 84 25 >65yrs -0.58 -1.54 0.21 1288.30 1.00 545 83 24 1 FALSE 0.72
non-small cell lung cancer KRAS_G12D MAP3K1 41 28 50-65yrs -0.94 -4.05 0.87 1125.49 1.00 1247 41 28 0 FALSE 0.32
non-small cell lung cancer KRAS_G12D MAP3K1 100 33 >65yrs -0.38 -2.12 1.02 1176.39 1.00 1998 98 31 2 FALSE 0.19
uterine cancer KRAS_G12D MAP3K1 25 31 50-65yrs -1.59 -4.12 0.60 76.53 1.04 461 24 30 1 FALSE 0.64
uterine cancer KRAS_G12D MAP3K1 18 27 >65yrs -1.83 -4.90 0.45 92.21 1.04 434 18 27 0 FALSE 0.68
colorectal cancer KRAS_G12D MAP3K1 267 83 Age:overall -0.55 -1.48 0.22 1340.65 1.00 1734 260 76 7 FALSE 0.71
non-small cell lung cancer KRAS_G12D MAP3K1 141 61 Age:overall -0.64 -3.12 1.22 1301.41 1.00 3245 139 59 2 FALSE 0.25
uterine cancer KRAS_G12D MAP3K1 43 58 Age:overall -1.67 -4.29 0.65 83.63 1.04 895 42 57 1 FALSE 0.65
colorectal cancer KRAS_G12D NSD1 35 15 <40yrs -0.98 -2.41 0.08 1111.47 1.00 169 35 15 0 FALSE 0.94
colorectal cancer KRAS_G12D NSD1 56 16 40-50yrs -0.62 -1.81 0.47 1275.71 1.00 385 53 13 3 FALSE 0.57
colorectal cancer KRAS_G12D NSD1 127 22 50-65yrs -0.79 -1.94 0.19 1043.04 1.00 821 125 20 2 FALSE 0.87
colorectal cancer KRAS_G12D NSD1 84 33 >65yrs -0.96 -2.12 -0.04 1169.42 1.00 540 83 32 1 FALSE 1.10
non-small cell lung cancer KRAS_G12D NSD1 41 31 50-65yrs -4.94 -11.72 -0.93 435.26 1.01 1243 41 31 0 FALSE 1.10
non-small cell lung cancer KRAS_G12D NSD1 100 55 >65yrs -4.96 -11.66 -1.06 511.14 1.01 1974 100 55 0 FALSE 1.14
uterine cancer KRAS_G12D NSD1 11 26 40-50yrs 0.36 -0.88 1.41 1672.13 1.00 67 7 22 4 FALSE 0.27
uterine cancer KRAS_G12D NSD1 26 52 50-65yrs -0.21 -1.62 0.88 1440.53 1.00 454 24 50 2 FALSE 0.14
uterine cancer KRAS_G12D NSD1 18 37 >65yrs -0.23 -1.78 0.99 1291.90 1.00 429 17 36 1 FALSE 0.12
colorectal cancer KRAS_G12D NSD1 302 86 Age:overall -0.83 -2.01 0.09 1193.07 1.00 1915 296 80 6 FALSE 1.00
non-small cell lung cancer KRAS_G12D NSD1 141 86 Age:overall -4.87 -11.45 -0.88 574.51 1.01 3217 141 86 0 FALSE 1.12
uterine cancer KRAS_G12D NSD1 55 115 Age:overall -0.03 -1.40 1.17 1288.30 1.00 950 48 108 7 FALSE 0.02
colorectal cancer KRAS_G12D FLT4 56 24 40-50yrs -0.62 -1.85 0.28 1370.84 1.00 375 55 23 1 TRUE 0.60
colorectal cancer KRAS_G12D FLT4 127 42 50-65yrs -0.67 -1.82 0.13 1532.26 1.00 802 125 40 2 TRUE 0.78
colorectal cancer KRAS_G12D FLT4 85 63 >65yrs -0.07 -0.79 0.65 1538.95 1.00 522 75 53 10 TRUE 0.07
non-small cell lung cancer KRAS_G12D FLT4 41 43 50-65yrs -0.56 -2.61 0.97 1135.85 1.00 1234 39 41 2 TRUE 0.27
non-small cell lung cancer KRAS_G12D FLT4 100 54 >65yrs -1.53 -5.15 0.23 1244.73 1.00 1977 100 54 0 TRUE 0.58
uterine cancer KRAS_G12D FLT4 25 21 50-65yrs -0.11 -2.03 1.22 895.80 1.00 470 24 20 1 TRUE 0.05
uterine cancer KRAS_G12D FLT4 18 20 >65yrs -0.08 -1.93 1.36 867.84 1.00 441 17 19 1 TRUE 0.03
colorectal cancer KRAS_G12D FLT4 268 129 Age:overall -0.46 -1.44 0.34 1503.14 1.00 1699 255 116 13 TRUE 0.49
non-small cell lung cancer KRAS_G12D FLT4 141 97 Age:overall -1.03 -3.77 0.95 980.30 1.00 3211 139 95 2 TRUE 0.43
uterine cancer KRAS_G12D FLT4 43 41 Age:overall -0.10 -2.02 1.40 742.83 1.00 911 41 39 2 TRUE 0.04
cancer of unknown primary KRAS_G12D PTPRD 21 23 50-65yrs -1.83 -4.38 0.09 245.81 1.01 275 20 22 1 FALSE 0.89
cancer of unknown primary KRAS_G12D PTPRD 26 28 >65yrs -2.07 -5.07 -0.08 291.81 1.01 311 26 28 0 FALSE 0.96
colorectal cancer KRAS_G12D PTPRD 56 18 40-50yrs -0.54 -1.41 0.16 825.13 1.00 383 55 17 1 FALSE 0.76
colorectal cancer KRAS_G12D PTPRD 127 43 50-65yrs -0.51 -1.36 0.20 810.61 1.00 809 122 38 5 FALSE 0.73
colorectal cancer KRAS_G12D PTPRD 84 32 >65yrs -0.54 -1.39 0.15 845.43 1.00 540 82 30 2 FALSE 0.79
non-small cell lung cancer KRAS_G12D PTPRD 8 13 40-50yrs -0.17 -1.40 0.76 1418.42 1.00 173 8 13 0 FALSE 0.12
non-small cell lung cancer KRAS_G12D PTPRD 41 163 50-65yrs -0.14 -0.96 0.52 1436.39 1.00 1142 37 159 4 FALSE 0.15
non-small cell lung cancer KRAS_G12D PTPRD 100 214 >65yrs 0.05 -0.52 0.62 1477.38 1.00 1856 88 202 12 FALSE 0.07
uterine cancer KRAS_G12D PTPRD 9 11 40-50yrs -1.81 -4.86 0.48 1409.62 1.00 76 8 10 1 FALSE 0.77
uterine cancer KRAS_G12D PTPRD 25 53 50-65yrs -2.26 -5.34 -0.28 1151.63 1.00 459 25 53 0 FALSE 1.07
uterine cancer KRAS_G12D PTPRD 18 29 >65yrs -2.18 -5.30 -0.06 1253.45 1.00 434 18 29 0 FALSE 0.99
cancer of unknown primary KRAS_G12D PTPRD 47 51 Age:overall -1.93 -4.57 0.05 252.09 1.01 586 46 50 1 FALSE 0.93
colorectal cancer KRAS_G12D PTPRD 267 93 Age:overall -0.52 -1.36 0.15 883.00 1.00 1732 259 85 8 FALSE 0.77
non-small cell lung cancer KRAS_G12D PTPRD 149 390 Age:overall -0.08 -0.91 0.63 1470.15 1.00 3171 133 374 16 FALSE 0.08
uterine cancer KRAS_G12D PTPRD 52 93 Age:overall -2.08 -5.14 -0.09 1313.83 1.00 969 51 92 1 FALSE 1.00
colorectal cancer KRAS_G12D RET 147 30 50-65yrs -0.87 -2.34 0.18 891.46 1.00 898 146 29 1 TRUE 0.75
colorectal cancer KRAS_G12D RET 95 20 >65yrs -0.57 -1.81 0.58 934.22 1.00 610 92 17 3 TRUE 0.46
non-small cell lung cancer KRAS_G12D RET 42 29 50-65yrs -1.25 -4.30 0.52 1113.49 1.00 1303 42 29 0 TRUE 0.45
non-small cell lung cancer KRAS_G12D RET 104 61 >65yrs -0.84 -2.72 0.46 1132.04 1.00 2022 102 59 2 TRUE 0.53
colorectal cancer KRAS_G12D RET 242 50 Age:overall -0.71 -2.14 0.44 985.62 1.00 1508 238 46 4 TRUE 0.55
non-small cell lung cancer KRAS_G12D RET 146 90 Age:overall -1.02 -3.42 0.62 1379.37 1.00 3325 144 88 2 TRUE 0.47
colorectal cancer KRAS_G12D KDM5A 56 21 40-50yrs -0.60 -1.61 0.12 153.07 1.02 382 55 20 1 FALSE 0.71
colorectal cancer KRAS_G12D KDM5A 129 35 50-65yrs -0.56 -1.49 0.18 159.74 1.02 815 125 31 4 FALSE 0.69
colorectal cancer KRAS_G12D KDM5A 84 30 >65yrs -0.58 -1.54 0.15 150.38 1.02 539 82 28 2 FALSE 0.71
non-small cell lung cancer KRAS_G12D KDM5A 41 25 50-65yrs -1.72 -4.67 0.33 1196.92 1.00 1250 41 25 0 FALSE 0.67
non-small cell lung cancer KRAS_G12D KDM5A 100 45 >65yrs -1.53 -4.42 0.32 952.70 1.00 1987 99 44 1 FALSE 0.72
uterine cancer KRAS_G12D KDM5A 25 31 50-65yrs -0.31 -2.03 1.08 726.51 1.00 465 23 29 2 FALSE 0.15
uterine cancer KRAS_G12D KDM5A 18 20 >65yrs -0.71 -3.32 1.00 972.01 1.00 440 18 20 0 FALSE 0.25
colorectal cancer KRAS_G12D KDM5A 269 86 Age:overall -0.58 -1.48 0.12 142.14 1.02 1736 262 79 7 FALSE 0.73
non-small cell lung cancer KRAS_G12D KDM5A 141 70 Age:overall -1.58 -4.30 0.43 1065.86 1.01 3237 140 69 1 FALSE 0.69
uterine cancer KRAS_G12D KDM5A 43 51 Age:overall -0.49 -2.78 1.20 930.25 1.00 905 41 49 2 FALSE 0.21
colorectal cancer KRAS_G12D PIK3C2G 54 21 40-50yrs -1.91 -3.65 -0.68 367.49 1.01 365 53 20 1 FALSE 1.91
colorectal cancer KRAS_G12D PIK3C2G 122 32 50-65yrs -1.93 -3.58 -0.75 322.26 1.01 793 121 31 1 FALSE 1.98
colorectal cancer KRAS_G12D PIK3C2G 81 28 >65yrs -1.96 -3.68 -0.75 326.21 1.01 527 81 28 0 FALSE 1.95
non-small cell lung cancer KRAS_G12D PIK3C2G 41 51 50-65yrs -0.06 -1.32 0.98 1394.50 1.00 1222 39 49 2 FALSE 0.04
non-small cell lung cancer KRAS_G12D PIK3C2G 100 73 >65yrs -0.13 -1.23 0.83 1274.42 1.00 1956 97 70 3 FALSE 0.10
colorectal cancer KRAS_G12D PIK3C2G 257 81 Age:overall -1.93 -3.65 -0.76 340.38 1.01 1685 255 79 2 FALSE 1.99
non-small cell lung cancer KRAS_G12D PIK3C2G 141 124 Age:overall -0.09 -1.35 1.12 1530.29 1.00 3178 136 119 5 FALSE 0.05
non-small cell lung cancer KRAS_G12D TSHR 41 23 50-65yrs -0.46 -3.36 1.03 1295.38 1.00 1251 41 23 0 TRUE 0.14
non-small cell lung cancer KRAS_G12D TSHR 101 42 >65yrs 0.03 -1.32 1.12 1316.81 1.00 1991 98 39 3 TRUE 0.02
non-small cell lung cancer KRAS_G12D TSHR 142 65 Age:overall -0.20 -2.33 1.22 1273.77 1.00 3242 139 62 3 TRUE 0.08
cancer of unknown primary KRAS_G12D CREBBP 21 22 50-65yrs -1.22 -3.91 0.36 1019.55 1.00 272 21 22 0 TRUE 0.52
cancer of unknown primary KRAS_G12D CREBBP 26 31 >65yrs -0.84 -2.66 0.55 1133.82 1.00 313 24 29 2 TRUE 0.51
colorectal cancer KRAS_G12D CREBBP 37 18 <40yrs -0.29 -1.03 0.48 1603.23 1.00 169 34 15 3 TRUE 0.35
colorectal cancer KRAS_G12D CREBBP 57 31 40-50yrs -0.30 -0.97 0.40 1519.03 1.00 375 53 27 4 TRUE 0.41
colorectal cancer KRAS_G12D CREBBP 129 58 50-65yrs -0.31 -0.95 0.31 1500.91 1.00 801 122 51 7 TRUE 0.48
colorectal cancer KRAS_G12D CREBBP 86 81 >65yrs -0.50 -1.24 0.10 1517.47 1.00 506 81 76 5 TRUE 0.88
non-small cell lung cancer KRAS_G12D CREBBP 41 48 50-65yrs -0.92 -3.73 0.47 1104.60 1.00 1229 41 48 0 TRUE 0.41
non-small cell lung cancer KRAS_G12D CREBBP 100 83 >65yrs -0.36 -1.59 0.68 1041.13 1.00 1954 96 79 4 TRUE 0.27
uterine cancer KRAS_G12D CREBBP 9 13 40-50yrs -1.07 -3.11 0.60 1198.60 1.00 73 8 12 1 TRUE 0.60
uterine cancer KRAS_G12D CREBBP 25 51 50-65yrs -1.21 -3.05 0.22 1432.22 1.00 450 24 50 1 TRUE 0.82
uterine cancer KRAS_G12D CREBBP 18 31 >65yrs -1.38 -3.58 0.25 1308.32 1.00 435 18 31 0 TRUE 0.80
cancer of unknown primary KRAS_G12D CREBBP 47 53 Age:overall -1.01 -3.17 0.53 1072.39 1.00 585 45 51 2 TRUE 0.51
colorectal cancer KRAS_G12D CREBBP 309 188 Age:overall -0.36 -0.98 0.23 1516.93 1.00 1851 290 169 19 TRUE 0.60
non-small cell lung cancer KRAS_G12D CREBBP 141 131 Age:overall -0.59 -2.46 0.74 1111.98 1.00 3183 137 127 4 TRUE 0.33
uterine cancer KRAS_G12D CREBBP 52 95 Age:overall -1.21 -3.17 0.25 1293.94 1.00 958 50 93 2 TRUE 0.77
non-small cell lung cancer KRAS_G12D BRIP1 41 30 50-65yrs -1.75 -5.04 0.36 1158.60 1.00 1245 41 30 0 TRUE 0.68
non-small cell lung cancer KRAS_G12D BRIP1 100 40 >65yrs -1.55 -4.47 0.30 981.22 1.00 1989 99 39 1 TRUE 0.68
non-small cell lung cancer KRAS_G12D BRIP1 141 70 Age:overall -1.62 -4.68 0.46 1121.77 1.00 3234 140 69 1 TRUE 0.67
colorectal cancer KRAS_G12D AXIN2 56 25 40-50yrs -0.60 -1.43 0.13 879.07 1.00 376 55 24 1 TRUE 0.90
colorectal cancer KRAS_G12D AXIN2 127 45 50-65yrs -0.56 -1.33 0.12 872.00 1.01 807 122 40 5 TRUE 0.87
colorectal cancer KRAS_G12D AXIN2 84 39 >65yrs -0.59 -1.36 0.14 892.24 1.01 534 81 36 3 TRUE 0.87
non-small cell lung cancer KRAS_G12D AXIN2 41 28 50-65yrs 0.02 -1.61 1.33 1261.87 1.00 1247 40 27 1 TRUE 0.01
non-small cell lung cancer KRAS_G12D AXIN2 100 30 >65yrs 0.10 -1.37 1.30 1343.14 1.00 2000 98 28 2 TRUE 0.05
uterine cancer KRAS_G12D AXIN2 25 26 50-65yrs -0.19 -1.98 1.22 852.32 1.00 466 23 24 2 TRUE 0.09
uterine cancer KRAS_G12D AXIN2 18 22 >65yrs -0.64 -3.48 0.95 1116.82 1.01 438 18 22 0 TRUE 0.22
colorectal cancer KRAS_G12D AXIN2 267 109 Age:overall -0.58 -1.36 0.11 895.03 1.00 1717 258 100 9 TRUE 0.91
non-small cell lung cancer KRAS_G12D AXIN2 141 58 Age:overall 0.08 -1.49 1.62 1239.39 1.00 3247 138 55 3 TRUE 0.03
uterine cancer KRAS_G12D AXIN2 43 48 Age:overall -0.40 -2.63 1.20 1172.17 1.00 904 41 46 2 TRUE 0.16
colorectal cancer KRAS_G12D DOT1L 36 19 <40yrs -0.16 -1.26 0.81 1433.44 1.00 170 32 15 4 FALSE 0.12
colorectal cancer KRAS_G12D DOT1L 56 12 40-50yrs -0.56 -1.86 0.53 1333.11 1.00 384 55 11 1 FALSE 0.44
colorectal cancer KRAS_G12D DOT1L 127 21 50-65yrs -0.90 -2.47 0.16 1376.66 1.00 823 127 21 0 FALSE 0.78
colorectal cancer KRAS_G12D DOT1L 84 32 >65yrs -0.49 -1.56 0.38 1085.49 1.00 540 81 29 3 FALSE 0.47
non-small cell lung cancer KRAS_G12D DOT1L 41 35 50-65yrs 0.32 -0.90 1.34 1382.67 1.00 1242 39 33 2 FALSE 0.24
non-small cell lung cancer KRAS_G12D DOT1L 100 66 >65yrs 0.28 -0.70 1.12 1290.03 1.00 1968 96 62 4 FALSE 0.25
colorectal cancer KRAS_G12D DOT1L 303 84 Age:overall -0.52 -1.56 0.40 1208.57 1.00 1917 295 76 8 FALSE 0.52
non-small cell lung cancer KRAS_G12D DOT1L 141 101 Age:overall 0.29 -0.95 1.46 1218.52 1.00 3210 135 95 6 FALSE 0.20
colorectal cancer KRAS_G12D PTPRS 35 26 <40yrs -0.11 -0.60 0.33 1416.81 1.00 159 32 23 3 FALSE 0.19
colorectal cancer KRAS_G12D PTPRS 56 51 40-50yrs -0.04 -0.49 0.44 1506.77 1.00 350 46 41 10 FALSE 0.07
colorectal cancer KRAS_G12D PTPRS 126 98 50-65yrs -0.09 -0.51 0.32 1422.03 1.00 748 113 85 13 FALSE 0.18
colorectal cancer KRAS_G12D PTPRS 81 79 >65yrs -0.16 -0.63 0.28 1399.05 1.00 490 76 74 5 FALSE 0.30
non-small cell lung cancer KRAS_G12D PTPRS 41 31 50-65yrs -1.40 -4.20 0.59 1321.89 1.00 1238 40 30 1 FALSE 0.61
non-small cell lung cancer KRAS_G12D PTPRS 100 46 >65yrs -1.90 -5.15 0.14 1170.83 1.00 1981 100 46 0 FALSE 0.79
colorectal cancer KRAS_G12D PTPRS 298 254 Age:overall -0.10 -0.53 0.30 1433.39 1.00 1747 267 223 31 FALSE 0.20
non-small cell lung cancer KRAS_G12D PTPRS 141 77 Age:overall -1.60 -4.36 0.46 1455.73 1.00 3219 140 76 1 FALSE 0.71
cancer of unknown primary KRAS_G12D SMARCA4 21 26 50-65yrs -0.42 -1.95 0.79 705.59 1.00 267 19 24 2 FALSE 0.27
cancer of unknown primary KRAS_G12D SMARCA4 26 32 >65yrs -0.54 -2.09 0.68 577.35 1.00 308 25 31 1 FALSE 0.36
colorectal cancer KRAS_G12D SMARCA4 37 19 <40yrs 0.01 -0.62 0.72 1216.73 1.00 171 32 14 5 FALSE 0.01
colorectal cancer KRAS_G12D SMARCA4 56 24 40-50yrs -0.09 -0.73 0.55 1235.30 1.00 377 53 21 3 FALSE 0.11
colorectal cancer KRAS_G12D SMARCA4 127 65 50-65yrs -0.14 -0.73 0.39 1372.61 1.00 797 121 59 6 FALSE 0.21
colorectal cancer KRAS_G12D SMARCA4 85 61 >65yrs -0.07 -0.65 0.49 1151.73 1.00 523 78 54 7 FALSE 0.10
non-small cell lung cancer KRAS_G12D SMARCA4 8 19 40-50yrs 0.09 -0.76 0.83 1317.99 1.00 165 8 19 0 FALSE 0.09
non-small cell lung cancer KRAS_G12D SMARCA4 42 119 50-65yrs 0.20 -0.50 0.84 1293.03 1.00 1163 36 113 6 FALSE 0.26
non-small cell lung cancer KRAS_G12D SMARCA4 100 174 >65yrs 0.14 -0.48 0.71 1392.01 1.00 1881 91 165 9 FALSE 0.20
uterine cancer KRAS_G12D SMARCA4 27 53 50-65yrs -0.07 -1.47 1.02 347.62 1.02 452 24 50 3 FALSE 0.04
uterine cancer KRAS_G12D SMARCA4 18 35 >65yrs -0.19 -1.72 1.00 479.97 1.01 433 17 34 1 FALSE 0.10
cancer of unknown primary KRAS_G12D SMARCA4 47 58 Age:overall -0.47 -2.04 0.81 614.45 1.00 575 44 55 3 FALSE 0.29
colorectal cancer KRAS_G12D SMARCA4 305 169 Age:overall -0.07 -0.65 0.44 1321.02 1.00 1868 284 148 21 FALSE 0.10
non-small cell lung cancer KRAS_G12D SMARCA4 150 312 Age:overall 0.14 -0.55 0.77 1240.51 1.00 3209 135 297 15 FALSE 0.17
uterine cancer KRAS_G12D SMARCA4 45 88 Age:overall -0.11 -1.61 1.09 406.94 1.01 885 41 84 4 FALSE 0.06
cancer of unknown primary KRAS_G12D PTPRT 21 22 50-65yrs -0.63 -2.30 0.94 599.64 1.01 273 19 20 2 FALSE 0.34
cancer of unknown primary KRAS_G12D PTPRT 26 32 >65yrs -1.29 -4.48 0.32 697.80 1.00 313 26 32 0 FALSE 0.50
colorectal cancer KRAS_G12D PTPRT 35 18 <40yrs -0.60 -1.09 -0.01 43.67 1.05 170 33 16 2 FALSE 1.27
colorectal cancer KRAS_G12D PTPRT 56 39 40-50yrs -0.59 -1.05 0.01 43.12 1.05 367 52 35 4 FALSE 1.25
colorectal cancer KRAS_G12D PTPRT 128 80 50-65yrs -0.60 -1.07 -0.03 41.49 1.05 770 122 74 6 FALSE 1.36
colorectal cancer KRAS_G12D PTPRT 84 48 >65yrs -0.60 -1.06 -0.02 41.16 1.05 525 80 44 4 FALSE 1.32
non-small cell lung cancer KRAS_G12D PTPRT 8 22 40-50yrs -0.37 -1.55 0.56 1418.24 1.00 163 8 22 0 FALSE 0.32
non-small cell lung cancer KRAS_G12D PTPRT 43 152 50-65yrs -0.05 -0.84 0.75 1247.30 1.00 1165 36 145 7 FALSE 0.05
non-small cell lung cancer KRAS_G12D PTPRT 101 175 >65yrs -0.37 -1.19 0.31 1359.37 1.00 1879 96 170 5 FALSE 0.49
uterine cancer KRAS_G12D PTPRT 9 12 40-50yrs -0.99 -2.87 0.62 980.69 1.00 77 8 11 1 FALSE 0.59
uterine cancer KRAS_G12D PTPRT 25 45 50-65yrs -1.11 -3.04 0.34 1202.57 1.00 453 24 44 1 FALSE 0.73
uterine cancer KRAS_G12D PTPRT 18 30 >65yrs -1.25 -3.40 0.25 1091.47 1.00 431 18 30 0 FALSE 0.73
cancer of unknown primary KRAS_G12D PTPRT 47 54 Age:overall -0.92 -3.18 0.80 668.69 1.00 586 45 52 2 FALSE 0.41
colorectal cancer KRAS_G12D PTPRT 303 185 Age:overall -0.60 -1.05 -0.04 40.20 1.05 1832 287 169 16 FALSE 1.35
non-small cell lung cancer KRAS_G12D PTPRT 152 349 Age:overall -0.26 -1.11 0.52 1463.42 1.00 3207 140 337 12 FALSE 0.29
uterine cancer KRAS_G12D PTPRT 52 87 Age:overall -1.13 -3.04 0.28 991.05 1.00 961 50 85 2 FALSE 0.73
colorectal cancer KRAS_G12D HGF 127 24 50-65yrs -0.41 -1.65 0.62 516.59 1.01 820 125 22 2 FALSE 0.33
colorectal cancer KRAS_G12D HGF 84 15 >65yrs -0.37 -1.64 0.71 508.99 1.01 553 82 13 2 FALSE 0.27
non-small cell lung cancer KRAS_G12D HGF 41 78 50-65yrs -0.40 -1.80 0.61 1119.08 1.00 1202 40 77 1 FALSE 0.29
non-small cell lung cancer KRAS_G12D HGF 100 105 >65yrs -0.04 -0.96 0.74 1227.89 1.00 1937 94 99 6 FALSE 0.03
colorectal cancer KRAS_G12D HGF 211 39 Age:overall -0.38 -1.73 0.69 611.30 1.00 1373 207 35 4 FALSE 0.26
non-small cell lung cancer KRAS_G12D HGF 141 183 Age:overall -0.19 -1.40 0.95 1290.88 1.00 3139 134 176 7 FALSE 0.12
colorectal cancer KRAS_G12D BLM 56 14 40-50yrs -1.52 -2.77 -0.22 7.80 1.14 384 56 14 0 TRUE 1.41
colorectal cancer KRAS_G12D BLM 127 21 50-65yrs -1.35 -2.40 0.02 4.49 1.26 823 124 18 3 TRUE 1.21
colorectal cancer KRAS_G12D BLM 84 26 >65yrs -1.56 -2.96 -0.23 10.74 1.11 542 84 26 0 TRUE 1.47
colorectal cancer KRAS_G12D BLM 267 61 Age:overall -1.48 -2.58 -0.19 5.93 1.19 1749 264 58 3 TRUE 1.50
cancer of unknown primary KRAS_G12D PIK3CA 21 32 50-65yrs -0.31 -1.49 0.62 217.19 1.01 265 20 31 1 TRUE 0.25
cancer of unknown primary KRAS_G12D PIK3CA 26 45 >65yrs -0.24 -1.32 0.62 226.99 1.01 302 23 42 3 TRUE 0.19
colorectal cancer KRAS_G12D PIK3CA 39 42 <40yrs 0.34 0.03 0.72 916.20 1.00 169 28 31 11 TRUE 1.35
colorectal cancer KRAS_G12D PIK3CA 64 90 40-50yrs 0.32 0.00 0.64 1076.75 1.00 356 48 74 16 TRUE 1.31
colorectal cancer KRAS_G12D PIK3CA 150 213 50-65yrs 0.32 0.02 0.61 815.08 1.00 769 114 177 36 TRUE 1.48
colorectal cancer KRAS_G12D PIK3CA 97 166 >65yrs 0.29 -0.02 0.60 868.42 1.00 503 74 143 23 TRUE 1.20
non-small cell lung cancer KRAS_G12D PIK3CA 42 90 50-65yrs -0.05 -1.14 0.78 1519.07 1.00 1246 40 88 2 TRUE 0.04
non-small cell lung cancer KRAS_G12D PIK3CA 104 140 >65yrs 0.19 -0.54 0.82 1371.85 1.00 1955 95 131 9 TRUE 0.23
uterine cancer KRAS_G12D PIK3CA 12 45 40-50yrs 1.04 0.43 1.86 240.47 1.02 63 3 36 9 TRUE 2.40
uterine cancer KRAS_G12D PIK3CA 28 271 50-65yrs 0.82 0.28 1.39 906.83 1.01 368 12 255 16 TRUE 2.43
uterine cancer KRAS_G12D PIK3CA 22 226 >65yrs 0.87 0.30 1.47 1167.70 1.01 321 8 212 14 TRUE 2.52
cancer of unknown primary KRAS_G12D PIK3CA 51 90 Age:overall -0.26 -1.37 0.66 239.38 1.01 635 46 85 5 TRUE 0.21
colorectal cancer KRAS_G12D PIK3CA 350 511 Age:overall 0.32 0.03 0.61 904.40 1.00 1797 264 425 86 TRUE 1.50
non-small cell lung cancer KRAS_G12D PIK3CA 146 230 Age:overall 0.09 -0.93 1.04 1601.15 1.00 3201 135 219 11 TRUE 0.06
uterine cancer KRAS_G12D PIK3CA 63 557 Age:overall 0.89 0.34 1.47 780.62 1.01 773 24 518 39 TRUE 2.58
non-small cell lung cancer KRAS_G12D GATA3 41 27 50-65yrs -1.58 -4.60 0.39 1029.08 1.00 1249 41 27 0 FALSE 0.63
non-small cell lung cancer KRAS_G12D GATA3 100 36 >65yrs -1.38 -3.94 0.47 960.20 1.00 1995 99 35 1 FALSE 0.63
non-small cell lung cancer KRAS_G12D GATA3 141 63 Age:overall -1.47 -4.33 0.48 1064.30 1.00 3244 140 62 1 FALSE 0.61
colorectal cancer KRAS_G12D ESR1 35 12 <40yrs -0.04 -1.02 0.88 1309.23 1.00 174 32 9 3 TRUE 0.03
colorectal cancer KRAS_G12D ESR1 127 24 50-65yrs -0.16 -1.10 0.63 1394.59 1.00 819 124 21 3 TRUE 0.15
colorectal cancer KRAS_G12D ESR1 84 28 >65yrs -0.24 -1.25 0.56 1408.78 1.00 542 82 26 2 TRUE 0.22
non-small cell lung cancer KRAS_G12D ESR1 41 18 50-65yrs -0.60 -3.31 0.98 630.53 1.00 1257 41 18 0 TRUE 0.23
non-small cell lung cancer KRAS_G12D ESR1 100 34 >65yrs -0.27 -1.89 1.09 784.27 1.00 1998 98 32 2 TRUE 0.14
colorectal cancer KRAS_G12D ESR1 246 64 Age:overall -0.16 -1.12 0.65 1427.69 1.00 1535 238 56 8 TRUE 0.14
non-small cell lung cancer KRAS_G12D ESR1 141 52 Age:overall -0.44 -2.62 1.15 634.40 1.00 3255 139 50 2 TRUE 0.19
colorectal cancer KRAS_G12D ALK 38 14 <40yrs -0.56 -1.40 0.19 42.40 1.06 194 35 11 3 TRUE 0.70
colorectal cancer KRAS_G12D ALK 63 25 40-50yrs -0.57 -1.46 0.19 41.27 1.06 404 61 23 2 TRUE 0.72
colorectal cancer KRAS_G12D ALK 147 44 50-65yrs -0.60 -1.46 0.15 38.23 1.06 886 145 42 2 TRUE 0.80
colorectal cancer KRAS_G12D ALK 95 32 >65yrs -0.59 -1.45 0.16 41.81 1.06 598 93 30 2 TRUE 0.76
non-small cell lung cancer KRAS_G12D ALK 42 76 50-65yrs -1.36 -4.93 0.33 1148.62 1.00 1262 42 76 0 TRUE 0.47
non-small cell lung cancer KRAS_G12D ALK 104 81 >65yrs -0.08 -1.15 0.90 1380.06 1.00 2006 99 76 5 TRUE 0.06
uterine cancer KRAS_G12D ALK 26 25 50-65yrs -4.96 -12.39 -0.38 532.45 1.00 530 26 25 0 TRUE 0.93
uterine cancer KRAS_G12D ALK 19 20 >65yrs -4.88 -12.06 -0.13 537.34 1.00 484 19 20 0 TRUE 0.91
colorectal cancer KRAS_G12D ALK 343 115 Age:overall -0.58 -1.44 0.15 39.89 1.06 2082 334 106 9 TRUE 0.79
non-small cell lung cancer KRAS_G12D ALK 146 157 Age:overall -0.70 -3.32 0.96 1286.18 1.00 3268 141 152 5 TRUE 0.28
uterine cancer KRAS_G12D ALK 45 45 Age:overall -4.88 -12.30 -0.18 521.91 1.00 1014 45 45 0 TRUE 0.91
colorectal cancer KRAS_G12D RNF43 36 31 <40yrs 0.04 -0.71 0.81 1384.17 1.00 163 30 25 6 TRUE 0.04
colorectal cancer KRAS_G12D RNF43 57 26 40-50yrs 0.18 -0.65 1.05 1398.44 1.00 376 51 20 6 TRUE 0.17
colorectal cancer KRAS_G12D RNF43 131 87 50-65yrs -0.36 -0.98 0.27 1471.99 1.00 775 123 79 8 TRUE 0.60
colorectal cancer KRAS_G12D RNF43 86 123 >65yrs -0.48 -1.12 0.08 1502.32 1.00 490 77 114 9 TRUE 0.90
pancreatic cancer KRAS_G12D RNF43 200 21 50-65yrs 0.32 -0.49 1.00 1193.42 1.00 404 192 13 8 TRUE 0.41
pancreatic cancer KRAS_G12D RNF43 257 52 >65yrs 0.54 0.04 1.05 1283.23 1.00 477 233 28 24 TRUE 1.40
uterine cancer KRAS_G12D RNF43 12 12 40-50yrs 1.78 0.30 3.27 1399.80 1.00 76 6 6 6 TRUE 1.83
uterine cancer KRAS_G12D RNF43 25 40 50-65yrs -0.44 -2.55 0.98 1202.91 1.00 455 24 39 1 TRUE 0.21
uterine cancer KRAS_G12D RNF43 18 41 >65yrs -1.00 -4.22 0.85 1277.66 1.00 422 18 41 0 TRUE 0.33
colorectal cancer KRAS_G12D RNF43 310 267 Age:overall -0.16 -0.80 0.46 1551.21 1.00 1804 281 238 29 TRUE 0.20
pancreatic cancer KRAS_G12D RNF43 457 73 Age:overall 0.42 -0.71 1.29 1236.48 1.00 881 425 41 32 TRUE 0.36
uterine cancer KRAS_G12D RNF43 55 93 Age:overall 0.12 -1.88 1.84 1329.40 1.00 953 48 86 7 TRUE 0.05
non-small cell lung cancer KRAS_G12D U2AF1 41 24 50-65yrs 0.48 -0.97 1.57 1514.28 1.00 1251 40 23 1 FALSE 0.35
non-small cell lung cancer KRAS_G12D U2AF1 101 51 >65yrs 0.65 -0.36 1.48 1544.79 1.00 1983 96 46 5 FALSE 0.78
non-small cell lung cancer KRAS_G12D U2AF1 142 75 Age:overall 0.56 -0.89 1.68 1429.91 1.00 3234 136 69 6 FALSE 0.39
colorectal cancer KRAS_G12D LATS1 122 26 50-65yrs -0.79 -2.25 0.37 1184.61 1.00 798 120 24 2 FALSE 0.63
colorectal cancer KRAS_G12D LATS1 81 14 >65yrs -0.80 -2.27 0.39 1308.11 1.00 539 80 13 1 FALSE 0.61
non-small cell lung cancer KRAS_G12D LATS1 41 27 50-65yrs -0.83 -3.25 0.82 709.36 1.00 1242 41 27 0 FALSE 0.35
non-small cell lung cancer KRAS_G12D LATS1 100 37 >65yrs -0.46 -2.21 0.91 684.61 1.00 1986 98 35 2 FALSE 0.25
colorectal cancer KRAS_G12D LATS1 203 40 Age:overall -0.80 -2.30 0.42 1254.23 1.00 1337 200 37 3 FALSE 0.60
non-small cell lung cancer KRAS_G12D LATS1 141 64 Age:overall -0.64 -2.82 0.95 672.91 1.00 3228 139 62 2 FALSE 0.29
colorectal cancer KRAS_G12D LATS2 122 35 50-65yrs 0.12 -0.69 0.86 1346.90 1.00 791 116 29 6 FALSE 0.11
colorectal cancer KRAS_G12D LATS2 81 21 >65yrs 0.00 -0.94 0.81 1236.49 1.00 534 79 19 2 FALSE 0.00
non-small cell lung cancer KRAS_G12D LATS2 41 24 50-65yrs -1.65 -4.96 0.51 733.47 1.01 1247 41 24 0 FALSE 0.62
non-small cell lung cancer KRAS_G12D LATS2 100 36 >65yrs -1.43 -4.42 0.42 665.54 1.01 1986 99 35 1 FALSE 0.61
colorectal cancer KRAS_G12D LATS2 203 56 Age:overall 0.06 -0.94 0.95 1311.22 1.00 1325 195 48 8 FALSE 0.04
non-small cell lung cancer KRAS_G12D LATS2 141 60 Age:overall -1.52 -4.59 0.59 724.92 1.01 3233 140 59 1 FALSE 0.60
colorectal cancer KRAS_G12D PTEN 38 16 <40yrs -0.48 -1.04 0.10 580.18 1.01 189 35 13 3 TRUE 0.93
colorectal cancer KRAS_G12D PTEN 63 45 40-50yrs -0.53 -1.12 0.02 705.02 1.01 390 61 43 2 TRUE 1.11
colorectal cancer KRAS_G12D PTEN 149 65 50-65yrs -0.50 -1.07 0.02 605.28 1.01 880 142 58 7 TRUE 1.09
colorectal cancer KRAS_G12D PTEN 95 59 >65yrs -0.50 -1.07 0.08 725.05 1.00 589 90 54 5 TRUE 1.05
non-small cell lung cancer KRAS_G12D PTEN 42 40 50-65yrs -0.72 -2.33 0.68 1340.26 1.00 1294 41 39 1 TRUE 0.45
non-small cell lung cancer KRAS_G12D PTEN 104 87 >65yrs -0.80 -2.21 0.30 1255.14 1.00 1999 102 85 2 TRUE 0.65
uterine cancer KRAS_G12D PTEN 17 69 40-50yrs 1.46 0.65 2.35 1278.09 1.00 55 2 54 15 TRUE 3.08
uterine cancer KRAS_G12D PTEN 34 321 50-65yrs 0.74 0.10 1.34 1592.65 1.00 364 14 301 20 TRUE 1.74
uterine cancer KRAS_G12D PTEN 26 223 >65yrs 0.80 0.17 1.44 1564.71 1.00 360 12 209 14 TRUE 1.86
colorectal cancer KRAS_G12D PTEN 345 185 Age:overall -0.50 -1.06 0.02 614.52 1.01 2048 328 168 17 TRUE 1.13
non-small cell lung cancer KRAS_G12D PTEN 146 127 Age:overall -0.75 -2.40 0.63 1205.06 1.00 3293 143 124 3 TRUE 0.47
uterine cancer KRAS_G12D PTEN 78 627 Age:overall 0.97 0.23 1.69 1477.05 1.00 801 28 577 50 TRUE 2.08
colorectal cancer KRAS_G12D BCOR 35 11 <40yrs -0.23 -1.04 0.48 534.65 1.02 174 34 10 1 FALSE 0.25
colorectal cancer KRAS_G12D BCOR 56 14 40-50yrs -0.15 -0.93 0.61 443.60 1.01 384 53 11 3 FALSE 0.15
colorectal cancer KRAS_G12D BCOR 127 40 50-65yrs -0.23 -0.98 0.41 750.59 1.01 810 123 36 4 FALSE 0.30
colorectal cancer KRAS_G12D BCOR 84 47 >65yrs -0.19 -0.90 0.42 402.48 1.01 532 79 42 5 FALSE 0.24
non-small cell lung cancer KRAS_G12D BCOR 41 46 50-65yrs -0.76 -4.68 0.77 978.85 1.00 1232 41 46 0 FALSE 0.23
non-small cell lung cancer KRAS_G12D BCOR 100 84 >65yrs 0.15 -0.84 1.01 817.69 1.00 1957 94 78 6 FALSE 0.13
uterine cancer KRAS_G12D BCOR 9 12 40-50yrs 0.78 -0.11 1.64 905.67 1.00 73 7 10 2 FALSE 1.16
uterine cancer KRAS_G12D BCOR 25 65 50-65yrs 0.76 0.03 1.46 775.14 1.00 437 19 59 6 FALSE 1.44
uterine cancer KRAS_G12D BCOR 18 58 >65yrs 0.74 -0.07 1.50 919.01 1.00 415 14 54 4 FALSE 1.23
colorectal cancer KRAS_G12D BCOR 302 112 Age:overall -0.20 -0.87 0.43 515.71 1.01 1900 289 99 13 FALSE 0.26
non-small cell lung cancer KRAS_G12D BCOR 141 130 Age:overall -0.28 -2.83 1.06 1201.76 1.00 3189 135 124 6 FALSE 0.12
uterine cancer KRAS_G12D BCOR 52 135 Age:overall 0.76 -0.02 1.51 876.86 1.00 925 40 123 12 FALSE 1.28
colorectal cancer KRAS_G12D CTNNB1 39 20 <40yrs 0.42 -0.08 0.91 831.17 1.00 183 34 15 5 TRUE 0.99
colorectal cancer KRAS_G12D CTNNB1 63 27 40-50yrs 0.36 -0.20 0.84 712.90 1.00 399 60 24 3 TRUE 0.77
colorectal cancer KRAS_G12D CTNNB1 149 76 50-65yrs 0.46 0.00 0.91 703.73 1.00 872 130 57 19 TRUE 1.32
colorectal cancer KRAS_G12D CTNNB1 95 40 >65yrs 0.34 -0.21 0.82 707.70 1.00 591 91 36 4 TRUE 0.70
non-small cell lung cancer KRAS_G12D CTNNB1 42 43 50-65yrs -0.84 -3.66 0.62 1159.99 1.00 1289 42 43 0 TRUE 0.32
non-small cell lung cancer KRAS_G12D CTNNB1 105 71 >65yrs -0.19 -1.42 0.78 1579.05 1.00 2013 101 67 4 TRUE 0.13
uterine cancer KRAS_G12D CTNNB1 9 13 40-50yrs -1.43 -3.65 0.26 1519.51 1.00 72 9 13 0 TRUE 0.82
uterine cancer KRAS_G12D CTNNB1 26 59 50-65yrs -0.88 -2.42 0.42 1668.53 1.00 494 24 57 2 TRUE 0.64
uterine cancer KRAS_G12D CTNNB1 19 58 >65yrs -1.57 -3.76 0.04 1501.54 1.00 446 19 58 0 TRUE 1.00
colorectal cancer KRAS_G12D CTNNB1 346 163 Age:overall 0.40 -0.05 0.85 638.83 1.00 2045 315 132 31 TRUE 1.07
non-small cell lung cancer KRAS_G12D CTNNB1 147 114 Age:overall -0.48 -2.57 0.95 1248.11 1.00 3302 143 110 4 TRUE 0.23
uterine cancer KRAS_G12D CTNNB1 55 143 Age:overall -1.13 -2.85 0.36 1602.99 1.00 1032 52 140 3 TRUE 0.79
cancer of unknown primary KRAS_G12D ARID1A 21 50 50-65yrs -0.43 -1.53 0.49 869.36 1.00 254 20 49 1 TRUE 0.38
cancer of unknown primary KRAS_G12D ARID1A 27 49 >65yrs -0.25 -1.20 0.65 684.49 1.00 302 22 44 5 TRUE 0.21
colorectal cancer KRAS_G12D ARID1A 38 40 <40yrs -0.08 -0.64 0.55 1520.30 1.00 162 30 32 8 TRUE 0.10
colorectal cancer KRAS_G12D ARID1A 60 51 40-50yrs -0.04 -0.61 0.63 1447.11 1.00 367 50 41 10 TRUE 0.05
colorectal cancer KRAS_G12D ARID1A 129 114 50-65yrs -0.37 -0.92 0.10 1533.20 1.00 761 120 105 9 TRUE 0.81
colorectal cancer KRAS_G12D ARID1A 85 110 >65yrs -0.40 -1.00 0.08 1537.02 1.00 496 78 103 7 TRUE 0.83
non-small cell lung cancer KRAS_G12D ARID1A 8 16 40-50yrs -0.64 -1.72 0.29 1367.53 1.00 168 8 16 0 TRUE 0.67
non-small cell lung cancer KRAS_G12D ARID1A 41 117 50-65yrs -0.66 -1.59 0.22 1389.99 1.00 1170 39 115 2 TRUE 0.79
non-small cell lung cancer KRAS_G12D ARID1A 100 149 >65yrs -0.58 -1.46 0.16 1354.40 1.00 1897 95 144 5 TRUE 0.77
pancreatic cancer KRAS_G12D ARID1A 200 50 50-65yrs 0.37 -0.20 0.82 881.60 1.00 385 183 33 17 TRUE 0.82
pancreatic cancer KRAS_G12D ARID1A 257 68 >65yrs 0.60 0.17 1.09 703.19 1.00 474 222 33 35 TRUE 1.99
uterine cancer KRAS_G12D ARID1A 11 47 40-50yrs 0.68 0.00 1.43 1375.60 1.00 53 5 41 6 TRUE 1.20
uterine cancer KRAS_G12D ARID1A 29 258 50-65yrs 0.62 0.06 1.20 1009.48 1.00 329 12 241 17 TRUE 1.43
uterine cancer KRAS_G12D ARID1A 21 212 >65yrs 0.56 -0.08 1.20 1316.28 1.00 329 10 201 11 TRUE 1.08
cancer of unknown primary KRAS_G12D ARID1A 52 110 Age:overall -0.36 -1.37 0.58 814.09 1.00 625 46 104 6 TRUE 0.32
colorectal cancer KRAS_G12D ARID1A 312 315 Age:overall -0.23 -0.72 0.26 1498.35 1.00 1786 278 281 34 TRUE 0.46
non-small cell lung cancer KRAS_G12D ARID1A 149 282 Age:overall -0.63 -1.55 0.20 1416.68 1.00 3235 142 275 7 TRUE 0.77
pancreatic cancer KRAS_G12D ARID1A 457 118 Age:overall 0.49 -0.11 1.10 1273.16 1.00 859 405 66 52 TRUE 0.90
uterine cancer KRAS_G12D ARID1A 61 517 Age:overall 0.61 -0.02 1.28 1410.77 1.00 711 27 483 34 TRUE 1.13
colorectal cancer KRAS_G12D PIK3R1 35 11 <40yrs -0.08 -0.74 0.52 945.54 1.00 174 34 10 1 TRUE 0.09
colorectal cancer KRAS_G12D PIK3R1 56 21 40-50yrs -0.07 -0.72 0.51 905.18 1.00 378 54 19 2 TRUE 0.08
colorectal cancer KRAS_G12D PIK3R1 130 48 50-65yrs -0.05 -0.68 0.48 860.60 1.00 804 122 40 8 TRUE 0.06
colorectal cancer KRAS_G12D PIK3R1 84 36 >65yrs -0.07 -0.71 0.52 928.50 1.00 540 80 32 4 TRUE 0.09
non-small cell lung cancer KRAS_G12D PIK3R1 41 18 50-65yrs 0.20 -1.42 1.53 1423.57 1.00 1257 40 17 1 TRUE 0.10
non-small cell lung cancer KRAS_G12D PIK3R1 100 35 >65yrs 0.14 -1.35 1.33 1280.71 1.00 1997 98 33 2 TRUE 0.08
uterine cancer KRAS_G12D PIK3R1 9 14 40-50yrs -1.05 -3.38 0.33 1585.88 1.00 69 9 14 0 TRUE 0.59
uterine cancer KRAS_G12D PIK3R1 27 119 50-65yrs -0.07 -1.05 0.82 1361.67 1.00 400 19 111 8 TRUE 0.05
uterine cancer KRAS_G12D PIK3R1 18 130 >65yrs -1.14 -2.96 0.03 1514.19 1.00 354 17 129 1 TRUE 0.93
colorectal cancer KRAS_G12D PIK3R1 305 116 Age:overall -0.06 -0.68 0.50 876.46 1.00 1896 290 101 15 TRUE 0.08
non-small cell lung cancer KRAS_G12D PIK3R1 141 53 Age:overall 0.17 -1.51 1.54 1365.83 1.00 3254 138 50 3 TRUE 0.08
uterine cancer KRAS_G12D PIK3R1 54 263 Age:overall -0.73 -2.21 0.35 1485.05 1.00 823 45 254 9 TRUE 0.60
colorectal cancer KRAS_G12D IKZF1 56 13 40-50yrs -0.17 -1.03 0.64 1260.87 1.00 383 54 11 2 TRUE 0.16
colorectal cancer KRAS_G12D IKZF1 128 31 50-65yrs -0.20 -1.02 0.50 1007.55 1.00 814 125 28 3 TRUE 0.22
colorectal cancer KRAS_G12D IKZF1 84 33 >65yrs -0.16 -0.96 0.57 1133.66 1.00 539 80 29 4 TRUE 0.17
non-small cell lung cancer KRAS_G12D IKZF1 41 44 50-65yrs -0.07 -1.73 1.29 1348.34 1.00 1233 39 42 2 TRUE 0.03
non-small cell lung cancer KRAS_G12D IKZF1 100 34 >65yrs -0.40 -2.19 0.91 1517.13 1.00 1996 99 33 1 TRUE 0.21
colorectal cancer KRAS_G12D IKZF1 268 77 Age:overall -0.17 -0.97 0.56 1064.30 1.00 1736 259 68 9 TRUE 0.18
non-small cell lung cancer KRAS_G12D IKZF1 141 78 Age:overall -0.24 -2.18 1.58 1553.09 1.00 3229 138 75 3 TRUE 0.10
cancer of unknown primary KRAS_G12D TERT 21 28 50-65yrs -2.00 -4.79 -0.11 635.60 1.01 267 20 27 1 TRUE 1.10
cancer of unknown primary KRAS_G12D TERT 26 43 >65yrs -2.32 -5.52 -0.45 284.15 1.02 299 26 43 0 TRUE 1.18
colorectal cancer KRAS_G12D TERT 59 23 40-50yrs 0.39 -0.22 1.04 1125.96 1.00 383 52 16 7 TRUE 0.64
colorectal cancer KRAS_G12D TERT 127 39 50-65yrs 0.26 -0.37 0.87 897.08 1.00 806 123 35 4 TRUE 0.40
colorectal cancer KRAS_G12D TERT 84 27 >65yrs 0.30 -0.33 0.89 1012.16 1.00 544 80 23 4 TRUE 0.47
non-small cell lung cancer KRAS_G12D TERT 41 59 50-65yrs -0.98 -4.08 0.35 999.28 1.00 1217 41 59 0 TRUE 0.36
non-small cell lung cancer KRAS_G12D TERT 100 99 >65yrs -0.27 -1.37 0.64 1216.40 1.00 1941 95 94 5 TRUE 0.23
uterine cancer KRAS_G12D TERT 9 11 40-50yrs -1.94 -5.04 0.21 1349.50 1.00 71 9 11 0 TRUE 0.81
uterine cancer KRAS_G12D TERT 25 28 50-65yrs -1.60 -4.29 0.38 1216.10 1.00 461 24 27 1 TRUE 0.68
uterine cancer KRAS_G12D TERT 18 24 >65yrs -1.91 -5.07 0.25 1287.83 1.00 433 18 24 0 TRUE 0.76
cancer of unknown primary KRAS_G12D TERT 47 71 Age:overall -2.12 -5.09 -0.20 632.65 1.01 566 46 70 1 TRUE 1.11
colorectal cancer KRAS_G12D TERT 270 89 Age:overall 0.32 -0.30 0.91 1011.90 1.00 1733 255 74 15 TRUE 0.53
non-small cell lung cancer KRAS_G12D TERT 141 158 Age:overall -0.60 -2.73 0.59 1171.20 1.00 3158 136 153 5 TRUE 0.32
uterine cancer KRAS_G12D TERT 52 63 Age:overall -1.80 -4.57 0.23 1319.98 1.00 965 51 62 1 TRUE 0.80
cancer of unknown primary KRAS_G12D FAT1 21 24 50-65yrs -1.34 -4.03 0.27 1102.11 1.00 269 21 24 0 FALSE 0.62
cancer of unknown primary KRAS_G12D FAT1 27 34 >65yrs -0.92 -2.75 0.47 1402.20 1.00 310 25 32 2 FALSE 0.58
colorectal cancer KRAS_G12D FAT1 36 24 <40yrs -0.58 -1.18 0.00 1146.81 1.00 170 34 22 2 FALSE 1.23
colorectal cancer KRAS_G12D FAT1 56 39 40-50yrs -0.61 -1.25 -0.05 1458.69 1.00 372 54 37 2 FALSE 1.35
colorectal cancer KRAS_G12D FAT1 129 81 50-65yrs -0.60 -1.18 -0.07 1250.25 1.00 791 123 75 6 FALSE 1.47
colorectal cancer KRAS_G12D FAT1 86 83 >65yrs -0.52 -1.06 0.04 1011.61 1.00 512 77 74 9 FALSE 1.18
non-small cell lung cancer KRAS_G12D FAT1 41 103 50-65yrs -0.51 -2.13 0.50 810.97 1.00 1180 40 102 1 FALSE 0.38
non-small cell lung cancer KRAS_G12D FAT1 101 194 >65yrs -0.06 -0.74 0.60 424.06 1.00 1866 91 184 10 FALSE 0.06
uterine cancer KRAS_G12D FAT1 11 32 40-50yrs -0.11 -1.35 1.07 1432.68 1.00 68 7 28 4 FALSE 0.07
uterine cancer KRAS_G12D FAT1 25 85 50-65yrs -0.78 -2.15 0.31 1452.25 1.00 445 23 83 2 FALSE 0.67
uterine cancer KRAS_G12D FAT1 18 58 >65yrs -1.21 -3.44 0.24 1456.73 1.00 416 18 58 0 FALSE 0.68
cancer of unknown primary KRAS_G12D FAT1 48 58 Age:overall -1.11 -3.23 0.46 1206.89 1.00 579 46 56 2 FALSE 0.61
colorectal cancer KRAS_G12D FAT1 307 227 Age:overall -0.58 -1.12 -0.05 1174.39 1.00 1845 288 208 19 FALSE 1.49
non-small cell lung cancer KRAS_G12D FAT1 142 297 Age:overall -0.28 -1.55 0.72 939.05 1.00 3046 131 286 11 FALSE 0.18
uterine cancer KRAS_G12D FAT1 54 175 Age:overall -0.69 -2.22 0.54 1465.54 1.00 929 48 169 6 FALSE 0.48
colorectal cancer KRAS_G12D FGFR4 127 17 50-65yrs 0.26 -1.01 1.20 1111.39 1.00 826 125 15 2 TRUE 0.19
colorectal cancer KRAS_G12D FGFR4 86 21 >65yrs 0.69 -0.26 1.60 1197.55 1.00 552 80 15 6 TRUE 0.85
colorectal cancer KRAS_G12D FGFR4 213 38 Age:overall 0.47 -0.84 1.62 1252.12 1.00 1378 205 30 8 TRUE 0.33
colorectal cancer KRAS_G12D CIC 36 15 <40yrs -0.07 -0.90 0.73 1439.99 1.00 172 33 12 3 TRUE 0.06
colorectal cancer KRAS_G12D CIC 57 25 40-50yrs 0.12 -0.64 0.99 1395.25 1.00 381 51 19 6 TRUE 0.12
colorectal cancer KRAS_G12D CIC 127 39 50-65yrs -0.22 -1.03 0.42 1401.10 1.00 811 123 35 4 TRUE 0.27
colorectal cancer KRAS_G12D CIC 85 58 >65yrs -0.38 -1.16 0.30 1345.07 1.00 523 82 55 3 TRUE 0.51
non-small cell lung cancer KRAS_G12D CIC 41 21 50-65yrs -0.45 -4.61 1.27 1364.68 1.00 1256 41 21 0 TRUE 0.12
non-small cell lung cancer KRAS_G12D CIC 100 66 >65yrs 0.54 -0.40 1.37 1510.22 1.00 1976 94 60 6 TRUE 0.65
uterine cancer KRAS_G12D CIC 25 37 50-65yrs -0.03 -1.52 1.16 1234.59 1.00 462 23 35 2 TRUE 0.01
uterine cancer KRAS_G12D CIC 18 25 >65yrs -0.06 -1.83 1.28 1410.11 1.00 436 17 24 1 TRUE 0.03
colorectal cancer KRAS_G12D CIC 305 137 Age:overall -0.14 -0.81 0.45 1032.45 1.00 1887 289 121 16 TRUE 0.17
non-small cell lung cancer KRAS_G12D CIC 141 87 Age:overall 0.06 -2.54 1.59 1419.27 1.00 3232 135 81 6 TRUE 0.02
uterine cancer KRAS_G12D CIC 43 62 Age:overall -0.03 -1.66 1.38 1424.12 1.00 898 40 59 3 TRUE 0.02
colorectal cancer KRAS_G12D KDM6A 57 11 40-50yrs 0.60 -0.12 1.29 499.75 1.00 387 53 7 4 FALSE 0.98
colorectal cancer KRAS_G12D KDM6A 127 26 50-65yrs 0.56 -0.14 1.21 533.76 1.00 820 122 21 5 FALSE 0.94
colorectal cancer KRAS_G12D KDM6A 84 20 >65yrs 0.55 -0.16 1.21 558.42 1.00 550 81 17 3 FALSE 0.90
non-small cell lung cancer KRAS_G12D KDM6A 41 27 50-65yrs -0.53 -3.59 1.13 1108.45 1.00 1249 41 27 0 FALSE 0.15
non-small cell lung cancer KRAS_G12D KDM6A 100 33 >65yrs 0.21 -1.29 1.41 1217.97 1.00 2000 97 30 3 FALSE 0.12
pancreatic cancer KRAS_G12D KDM6A 200 19 50-65yrs 0.34 -0.36 1.12 1231.17 1.00 407 191 10 9 FALSE 0.48
pancreatic cancer KRAS_G12D KDM6A 254 38 >65yrs 0.19 -0.46 0.77 1320.85 1.00 479 241 25 13 FALSE 0.27
uterine cancer KRAS_G12D KDM6A 25 29 50-65yrs -1.30 -3.94 0.71 127.02 1.03 464 24 28 1 FALSE 0.52
uterine cancer KRAS_G12D KDM6A 18 17 >65yrs -1.53 -4.71 0.75 259.74 1.02 440 18 17 0 FALSE 0.55
colorectal cancer KRAS_G12D KDM6A 268 57 Age:overall 0.57 -0.12 1.23 498.20 1.00 1757 256 45 12 FALSE 0.97
non-small cell lung cancer KRAS_G12D KDM6A 141 60 Age:overall -0.15 -2.66 1.49 1327.37 1.00 3249 138 57 3 FALSE 0.05
pancreatic cancer KRAS_G12D KDM6A 454 57 Age:overall 0.26 -0.61 1.18 1401.91 1.00 886 432 35 22 FALSE 0.23
uterine cancer KRAS_G12D KDM6A 43 46 Age:overall -1.36 -4.21 0.83 198.22 1.02 904 42 45 1 FALSE 0.51
colorectal cancer KRAS_G12D NCOR1 35 12 <40yrs -0.51 -1.22 0.10 937.67 1.00 174 35 12 0 FALSE 0.83
colorectal cancer KRAS_G12D NCOR1 57 22 40-50yrs -0.42 -1.10 0.26 1039.67 1.00 381 52 17 5 FALSE 0.66
colorectal cancer KRAS_G12D NCOR1 127 56 50-65yrs -0.47 -1.15 0.13 939.32 1.00 800 121 50 6 FALSE 0.83
colorectal cancer KRAS_G12D NCOR1 84 45 >65yrs -0.53 -1.25 0.07 747.16 1.00 529 83 44 1 FALSE 0.92
non-small cell lung cancer KRAS_G12D NCOR1 41 41 50-65yrs -0.96 -3.71 0.53 1282.97 1.00 1238 41 41 0 FALSE 0.38
non-small cell lung cancer KRAS_G12D NCOR1 101 56 >65yrs -0.35 -1.78 0.80 1317.29 1.00 1979 98 53 3 FALSE 0.22
uterine cancer KRAS_G12D NCOR1 9 11 40-50yrs -0.24 -1.96 1.16 1022.75 1.00 76 8 10 1 FALSE 0.12
uterine cancer KRAS_G12D NCOR1 26 50 50-65yrs -0.13 -1.35 0.95 1233.82 1.00 461 23 47 3 FALSE 0.08
uterine cancer KRAS_G12D NCOR1 18 24 >65yrs -0.55 -2.68 0.80 1359.33 1.00 437 18 24 0 FALSE 0.28
colorectal cancer KRAS_G12D NCOR1 303 135 Age:overall -0.49 -1.14 0.12 721.41 1.00 1884 291 123 12 FALSE 0.89
non-small cell lung cancer KRAS_G12D NCOR1 142 97 Age:overall -0.64 -2.74 0.86 1437.01 1.00 3217 139 94 3 FALSE 0.29
uterine cancer KRAS_G12D NCOR1 53 85 Age:overall -0.30 -1.81 0.96 1359.73 1.00 974 49 81 4 FALSE 0.18
colorectal cancer KRAS_G12D POLE 35 22 <40yrs -0.34 -1.00 0.26 145.69 1.03 170 32 19 3 TRUE 0.58
colorectal cancer KRAS_G12D POLE 56 23 40-50yrs -0.37 -1.04 0.18 63.08 1.05 378 54 21 2 TRUE 0.63
colorectal cancer KRAS_G12D POLE 128 51 50-65yrs -0.39 -1.03 0.14 98.45 1.04 802 124 47 4 TRUE 0.72
colorectal cancer KRAS_G12D POLE 84 45 >65yrs -0.34 -0.94 0.21 162.15 1.03 532 79 40 5 TRUE 0.64
non-small cell lung cancer KRAS_G12D POLE 41 56 50-65yrs -0.47 -1.87 0.72 59.99 1.04 1222 40 55 1 TRUE 0.32
non-small cell lung cancer KRAS_G12D POLE 100 75 >65yrs -0.37 -1.52 0.67 60.38 1.04 1962 97 72 3 TRUE 0.28
uterine cancer KRAS_G12D POLE 10 15 40-50yrs 0.96 -0.25 2.07 1415.12 1.00 73 6 11 4 TRUE 0.97
uterine cancer KRAS_G12D POLE 25 60 50-65yrs 0.09 -1.20 1.06 1294.70 1.00 455 23 58 2 TRUE 0.06
uterine cancer KRAS_G12D POLE 18 31 >65yrs 0.46 -0.77 1.55 1448.67 1.00 438 16 29 2 TRUE 0.37
colorectal cancer KRAS_G12D POLE 303 141 Age:overall -0.36 -0.95 0.16 67.25 1.05 1882 289 127 14 TRUE 0.71
non-small cell lung cancer KRAS_G12D POLE 141 131 Age:overall -0.42 -1.79 0.70 79.56 1.04 3184 137 127 4 TRUE 0.27
uterine cancer KRAS_G12D POLE 53 106 Age:overall 0.50 -0.66 1.63 1482.02 1.00 966 45 98 8 TRUE 0.42
non-small cell lung cancer KRAS_G12D CUL3 41 24 50-65yrs -1.74 -5.15 0.26 223.46 1.02 1253 41 24 0 FALSE 0.64
non-small cell lung cancer KRAS_G12D CUL3 100 50 >65yrs -1.53 -4.65 0.24 205.63 1.02 1984 99 49 1 FALSE 0.68
non-small cell lung cancer KRAS_G12D CUL3 141 74 Age:overall -1.61 -4.88 0.42 234.59 1.02 3237 140 73 1 FALSE 0.66
colorectal cancer KRAS_G12D ABL1 63 14 40-50yrs -0.74 -1.78 0.16 898.21 1.00 412 62 13 1 TRUE 0.88
colorectal cancer KRAS_G12D ABL1 147 29 50-65yrs -0.75 -1.79 0.10 1137.38 1.00 904 145 27 2 TRUE 0.91
colorectal cancer KRAS_G12D ABL1 95 24 >65yrs -0.73 -1.75 0.13 1104.84 1.00 604 93 22 2 TRUE 0.86
colorectal cancer KRAS_G12D ABL1 305 67 Age:overall -0.74 -1.77 0.12 1138.09 1.00 1920 300 62 5 TRUE 0.89
colorectal cancer KRAS_G12D FOXP1 35 12 <40yrs -0.47 -1.54 0.25 12.85 1.19 173 34 11 1 FALSE 0.46
colorectal cancer KRAS_G12D FOXP1 56 17 40-50yrs -0.48 -1.59 0.26 14.01 1.19 380 55 16 1 FALSE 0.46
colorectal cancer KRAS_G12D FOXP1 127 27 50-65yrs -0.48 -1.50 0.20 9.51 1.21 817 125 25 2 FALSE 0.48
colorectal cancer KRAS_G12D FOXP1 84 14 >65yrs -0.46 -1.48 0.24 11.74 1.18 553 82 12 2 FALSE 0.45
colorectal cancer KRAS_G12D FOXP1 302 70 Age:overall -0.47 -1.48 0.20 9.70 1.22 1923 296 64 6 FALSE 0.49
colorectal cancer KRAS_G12D NOTCH2 122 24 50-65yrs -0.20 -1.44 0.92 1045.31 1.00 798 118 20 4 TRUE 0.13
colorectal cancer KRAS_G12D NOTCH2 81 31 >65yrs -0.89 -2.56 0.29 937.23 1.00 528 80 30 1 TRUE 0.65
non-small cell lung cancer KRAS_G12D NOTCH2 41 43 50-65yrs -0.65 -4.17 0.81 1226.75 1.00 1234 41 43 0 TRUE 0.21
non-small cell lung cancer KRAS_G12D NOTCH2 100 67 >65yrs 0.14 -0.96 1.09 1116.71 1.00 1961 95 62 5 TRUE 0.10
colorectal cancer KRAS_G12D NOTCH2 203 55 Age:overall -0.54 -2.10 0.92 1350.14 1.00 1326 198 50 5 TRUE 0.31
non-small cell lung cancer KRAS_G12D NOTCH2 141 110 Age:overall -0.21 -2.41 1.16 1284.87 1.00 3195 136 105 5 TRUE 0.09
non-small cell lung cancer KRAS_G12D DDR2 41 39 50-65yrs -1.96 -5.00 0.11 812.16 1.00 1235 41 39 0 TRUE 0.85
non-small cell lung cancer KRAS_G12D DDR2 100 56 >65yrs -1.74 -4.30 0.02 536.77 1.01 1973 99 55 1 TRUE 0.89
uterine cancer KRAS_G12D DDR2 25 30 50-65yrs -0.38 -2.35 1.05 858.38 1.00 468 24 29 1 TRUE 0.18
uterine cancer KRAS_G12D DDR2 18 18 >65yrs -0.24 -2.34 1.26 1147.49 1.00 444 17 17 1 TRUE 0.10
non-small cell lung cancer KRAS_G12D DDR2 141 95 Age:overall -1.83 -4.55 0.28 476.74 1.00 3208 140 94 1 TRUE 0.84
uterine cancer KRAS_G12D DDR2 43 48 Age:overall -0.31 -2.47 1.31 1026.26 1.00 912 41 46 2 TRUE 0.13
colorectal cancer KRAS_G12D TGFBR2 56 18 40-50yrs -0.17 -1.10 0.62 1246.60 1.00 379 54 16 2 TRUE 0.16
colorectal cancer KRAS_G12D TGFBR2 127 42 50-65yrs -0.34 -1.38 0.39 1206.38 1.00 803 125 40 2 TRUE 0.36
colorectal cancer KRAS_G12D TGFBR2 84 46 >65yrs 0.07 -0.70 0.78 659.74 1.00 530 75 37 9 TRUE 0.07
non-small cell lung cancer KRAS_G12D TGFBR2 41 28 50-65yrs 0.36 -1.20 1.70 1088.11 1.00 1251 39 26 2 TRUE 0.20
non-small cell lung cancer KRAS_G12D TGFBR2 100 26 >65yrs -0.03 -1.80 1.30 1192.89 1.00 2004 99 25 1 TRUE 0.01
colorectal cancer KRAS_G12D TGFBR2 267 106 Age:overall -0.14 -1.03 0.60 1091.11 1.00 1712 254 93 13 TRUE 0.15
non-small cell lung cancer KRAS_G12D TGFBR2 141 54 Age:overall 0.16 -1.62 1.74 1392.71 1.00 3255 138 51 3 TRUE 0.07
colorectal cancer KRAS_G12D SMO 64 14 40-50yrs -0.16 -0.86 0.58 448.85 1.01 411 61 11 3 TRUE 0.20
colorectal cancer KRAS_G12D SMO 147 29 50-65yrs -0.18 -0.88 0.51 485.66 1.01 905 143 25 4 TRUE 0.24
colorectal cancer KRAS_G12D SMO 95 21 >65yrs -0.20 -0.96 0.49 522.06 1.01 607 94 20 1 TRUE 0.26
non-small cell lung cancer KRAS_G12D SMO 42 25 50-65yrs 0.90 -0.23 2.05 1297.67 1.00 1311 39 22 3 TRUE 0.97
non-small cell lung cancer KRAS_G12D SMO 104 45 >65yrs 0.56 -0.50 1.49 1332.09 1.00 2038 101 42 3 TRUE 0.59
uterine cancer KRAS_G12D SMO 26 21 50-65yrs -0.20 -2.17 1.28 1152.72 1.00 533 25 20 1 TRUE 0.08
uterine cancer KRAS_G12D SMO 19 23 >65yrs -0.18 -2.27 1.23 1098.14 1.00 483 18 22 1 TRUE 0.08
colorectal cancer KRAS_G12D SMO 306 64 Age:overall -0.18 -0.88 0.52 452.43 1.01 1923 298 56 8 TRUE 0.24
non-small cell lung cancer KRAS_G12D SMO 146 70 Age:overall 0.74 -0.49 1.88 1551.82 1.00 3349 140 64 6 TRUE 0.63
uterine cancer KRAS_G12D SMO 45 44 Age:overall -0.19 -2.21 1.35 1133.48 1.00 1016 43 42 2 TRUE 0.08
colorectal cancer KRAS_G12D RPS6KA4 122 28 50-65yrs -0.47 -1.79 0.55 634.05 1.00 793 119 25 3 FALSE 0.37
colorectal cancer KRAS_G12D RPS6KA4 81 16 >65yrs -0.55 -1.98 0.52 611.53 1.00 538 80 15 1 FALSE 0.41
colorectal cancer KRAS_G12D RPS6KA4 203 44 Age:overall -0.51 -1.90 0.59 689.38 1.00 1331 199 40 4 FALSE 0.37
colorectal cancer KRAS_G12D KMT2A 35 22 <40yrs -0.06 -0.66 0.53 1211.87 1.00 169 32 19 3 FALSE 0.07
colorectal cancer KRAS_G12D KMT2A 56 22 40-50yrs -0.10 -0.75 0.48 1186.06 1.00 381 54 20 2 FALSE 0.12
colorectal cancer KRAS_G12D KMT2A 128 53 50-65yrs -0.07 -0.64 0.45 1125.18 1.00 804 121 46 7 FALSE 0.09
colorectal cancer KRAS_G12D KMT2A 84 51 >65yrs -0.04 -0.63 0.51 1281.08 1.00 532 77 44 7 FALSE 0.05
non-small cell lung cancer KRAS_G12D KMT2A 41 33 50-65yrs -1.13 -4.69 0.63 51.79 1.07 1242 40 32 1 FALSE 0.47
non-small cell lung cancer KRAS_G12D KMT2A 100 75 >65yrs -1.37 -4.76 0.17 56.09 1.06 1960 99 74 1 FALSE 0.66
uterine cancer KRAS_G12D KMT2A 10 13 40-50yrs -0.82 -2.71 0.89 1051.18 1.00 75 8 11 2 FALSE 0.46
uterine cancer KRAS_G12D KMT2A 25 50 50-65yrs -1.53 -3.97 0.02 400.24 1.01 454 25 50 0 FALSE 0.86
uterine cancer KRAS_G12D KMT2A 18 36 >65yrs -1.45 -3.93 0.20 667.73 1.00 433 18 36 0 FALSE 0.75
colorectal cancer KRAS_G12D KMT2A 303 148 Age:overall -0.06 -0.63 0.44 1215.22 1.00 1886 284 129 19 FALSE 0.09
non-small cell lung cancer KRAS_G12D KMT2A 141 108 Age:overall -1.24 -4.73 0.62 58.03 1.06 3202 139 106 2 FALSE 0.53
uterine cancer KRAS_G12D KMT2A 53 99 Age:overall -1.27 -3.41 0.30 1001.35 1.00 962 51 97 2 FALSE 0.77
colorectal cancer KRAS_G12D JAK3 147 28 50-65yrs -1.51 -3.20 -0.33 468.66 1.01 901 146 27 1 TRUE 1.38
colorectal cancer KRAS_G12D JAK3 95 22 >65yrs -1.52 -3.30 -0.30 544.46 1.01 608 94 21 1 TRUE 1.32
non-small cell lung cancer KRAS_G12D JAK3 42 33 50-65yrs -0.34 -4.14 1.28 1185.33 1.00 1300 42 33 0 TRUE 0.10
non-small cell lung cancer KRAS_G12D JAK3 104 48 >65yrs 0.76 -0.28 1.68 1368.61 1.00 2038 98 42 6 TRUE 0.90
colorectal cancer KRAS_G12D JAK3 242 50 Age:overall -1.51 -3.20 -0.29 555.33 1.01 1509 240 48 2 TRUE 1.33
non-small cell lung cancer KRAS_G12D JAK3 146 81 Age:overall 0.22 -2.40 1.78 1172.75 1.00 3338 140 75 6 TRUE 0.08
non-small cell lung cancer KRAS_G12D PAK7 41 45 50-65yrs -0.23 -1.49 0.80 1388.35 1.00 1227 40 44 1 FALSE 0.15
non-small cell lung cancer KRAS_G12D PAK7 100 81 >65yrs -0.12 -1.09 0.70 1265.33 1.00 1950 96 77 4 FALSE 0.10
non-small cell lung cancer KRAS_G12D PAK7 141 126 Age:overall -0.17 -1.39 0.86 1446.17 1.00 3177 136 121 5 FALSE 0.11
non-small cell lung cancer KRAS_G12D STAG2 41 38 50-65yrs -0.04 -1.29 1.17 1427.93 1.00 1243 39 36 2 TRUE 0.02
non-small cell lung cancer KRAS_G12D STAG2 100 61 >65yrs -0.27 -1.55 0.74 1225.93 1.00 1970 98 59 2 TRUE 0.19
uterine cancer KRAS_G12D STAG2 12 13 40-50yrs 0.89 -0.47 2.21 1519.48 1.00 76 8 9 4 TRUE 0.75
uterine cancer KRAS_G12D STAG2 25 42 50-65yrs -0.16 -1.86 1.02 1538.69 1.00 461 24 41 1 TRUE 0.08
uterine cancer KRAS_G12D STAG2 18 24 >65yrs 0.17 -1.43 1.45 1520.60 1.00 438 17 23 1 TRUE 0.09
non-small cell lung cancer KRAS_G12D STAG2 141 99 Age:overall -0.16 -1.59 1.14 1442.10 1.00 3213 137 95 4 TRUE 0.09
uterine cancer KRAS_G12D STAG2 55 79 Age:overall 0.29 -1.19 1.53 1551.18 1.00 975 49 73 6 TRUE 0.17
colorectal cancer KRAS_G12D BRCA2 36 26 <40yrs -0.66 -1.40 0.13 1409.96 1.00 173 32 22 4 TRUE 1.02
colorectal cancer KRAS_G12D BRCA2 56 38 40-50yrs -0.88 -1.70 -0.17 1349.82 1.00 373 55 37 1 TRUE 1.59
colorectal cancer KRAS_G12D BRCA2 127 61 50-65yrs -0.66 -1.33 0.04 1166.64 1.00 808 120 54 7 TRUE 1.21
colorectal cancer KRAS_G12D BRCA2 84 65 >65yrs -0.97 -1.89 -0.25 1217.58 1.00 513 83 64 1 TRUE 1.66
non-small cell lung cancer KRAS_G12D BRCA2 41 58 50-65yrs -1.27 -4.48 0.25 1153.67 1.00 1219 41 58 0 TRUE 0.55
non-small cell lung cancer KRAS_G12D BRCA2 100 72 >65yrs -0.64 -2.08 0.54 1300.07 1.00 1968 97 69 3 TRUE 0.48
uterine cancer KRAS_G12D BRCA2 10 28 40-50yrs -0.92 -2.64 0.52 1489.57 1.00 70 8 26 2 TRUE 0.59
uterine cancer KRAS_G12D BRCA2 25 51 50-65yrs -1.30 -3.26 0.20 1497.39 1.00 452 24 50 1 TRUE 0.85
uterine cancer KRAS_G12D BRCA2 18 43 >65yrs -1.61 -4.02 0.08 1501.44 1.00 430 18 43 0 TRUE 0.90
colorectal cancer KRAS_G12D BRCA2 303 190 Age:overall -0.78 -1.44 -0.15 1214.48 1.00 1867 290 177 13 TRUE 1.69
non-small cell lung cancer KRAS_G12D BRCA2 141 130 Age:overall -0.92 -3.05 0.73 1426.38 1.00 3187 138 127 3 TRUE 0.47
uterine cancer KRAS_G12D BRCA2 54 134 Age:overall -1.30 -3.10 0.16 1486.12 1.00 980 51 131 3 TRUE 0.90
colorectal cancer KRAS_G12D NOTCH3 35 22 <40yrs -0.74 -1.54 0.01 1278.29 1.00 168 33 20 2 TRUE 1.24
colorectal cancer KRAS_G12D NOTCH3 56 28 40-50yrs -0.65 -1.48 0.09 1331.56 1.00 374 52 24 4 TRUE 1.03
colorectal cancer KRAS_G12D NOTCH3 127 71 50-65yrs -0.80 -1.57 -0.18 1480.21 1.00 789 123 67 4 TRUE 1.69
colorectal cancer KRAS_G12D NOTCH3 84 79 >65yrs -0.81 -1.54 -0.17 1254.57 1.00 507 80 75 4 TRUE 1.64
non-small cell lung cancer KRAS_G12D NOTCH3 41 44 50-65yrs -1.15 -3.90 0.34 1070.19 1.00 1233 41 44 0 TRUE 0.48
non-small cell lung cancer KRAS_G12D NOTCH3 100 78 >65yrs -0.65 -2.21 0.46 752.09 1.00 1959 97 75 3 TRUE 0.50
uterine cancer KRAS_G12D NOTCH3 25 42 50-65yrs -2.03 -5.11 -0.05 665.60 1.00 456 25 42 0 TRUE 0.87
uterine cancer KRAS_G12D NOTCH3 18 41 >65yrs -1.68 -4.42 0.29 701.87 1.00 425 17 40 1 TRUE 0.79
colorectal cancer KRAS_G12D NOTCH3 302 200 Age:overall -0.75 -1.44 -0.15 1265.03 1.00 1838 288 186 14 TRUE 1.63
non-small cell lung cancer KRAS_G12D NOTCH3 141 122 Age:overall -0.89 -2.92 0.61 1002.03 1.00 3192 138 119 3 TRUE 0.48
uterine cancer KRAS_G12D NOTCH3 43 83 Age:overall -1.84 -4.83 0.16 687.19 1.00 881 42 82 1 TRUE 0.84
colorectal cancer KRAS_G12D NOTCH4 34 12 <40yrs -0.20 -0.92 0.42 1302.42 1.00 168 33 11 1 TRUE 0.26
colorectal cancer KRAS_G12D NOTCH4 54 19 40-50yrs -0.16 -0.84 0.52 1389.08 1.01 368 51 16 3 TRUE 0.20
colorectal cancer KRAS_G12D NOTCH4 123 43 50-65yrs -0.16 -0.76 0.42 1395.52 1.01 782 117 37 6 TRUE 0.21
colorectal cancer KRAS_G12D NOTCH4 82 48 >65yrs -0.21 -0.89 0.37 957.95 1.01 515 78 44 4 TRUE 0.29
non-small cell lung cancer KRAS_G12D NOTCH4 41 49 50-65yrs -0.93 -3.60 0.45 1323.37 1.00 1222 41 49 0 TRUE 0.36
non-small cell lung cancer KRAS_G12D NOTCH4 100 84 >65yrs -0.38 -1.57 0.60 1167.40 1.00 1944 96 80 4 TRUE 0.30
colorectal cancer KRAS_G12D NOTCH4 293 122 Age:overall -0.19 -0.84 0.39 1336.60 1.01 1833 279 108 14 TRUE 0.27
non-small cell lung cancer KRAS_G12D NOTCH4 141 133 Age:overall -0.64 -2.59 0.65 1441.79 1.00 3166 137 129 4 TRUE 0.34
colorectal cancer KRAS_G12D FGFR3 147 25 50-65yrs -0.97 -3.08 0.29 55.85 1.05 907 144 22 3 TRUE 0.67
colorectal cancer KRAS_G12D FGFR3 95 24 >65yrs -1.60 -4.64 -0.06 369.02 1.01 604 95 24 0 TRUE 0.67
colorectal cancer KRAS_G12D FGFR3 242 49 Age:overall -1.25 -3.19 0.21 129.75 1.02 1511 239 46 3 TRUE 0.70
non-small cell lung cancer KRAS_G12D MAP3K13 41 21 50-65yrs -1.41 -4.70 0.67 1283.86 1.00 1247 41 21 0 FALSE 0.52
non-small cell lung cancer KRAS_G12D MAP3K13 100 30 >65yrs -1.18 -3.92 0.71 1345.19 1.00 1993 99 29 1 FALSE 0.50
non-small cell lung cancer KRAS_G12D MAP3K13 141 51 Age:overall -1.28 -4.17 0.74 1309.56 1.00 3240 140 50 1 FALSE 0.49
colorectal cancer KRAS_G12D IGF1R 35 11 <40yrs -0.35 -1.28 0.50 1090.05 1.00 176 33 9 2 TRUE 0.36
colorectal cancer KRAS_G12D IGF1R 56 11 40-50yrs -0.42 -1.31 0.45 820.34 1.00 385 55 10 1 TRUE 0.44
colorectal cancer KRAS_G12D IGF1R 127 25 50-65yrs -0.49 -1.43 0.30 1128.74 1.00 819 126 24 1 TRUE 0.56
colorectal cancer KRAS_G12D IGF1R 84 33 >65yrs -0.33 -1.16 0.45 1244.81 1.00 540 80 29 4 TRUE 0.37
non-small cell lung cancer KRAS_G12D IGF1R 41 29 50-65yrs -1.60 -5.30 0.59 1332.27 1.00 1245 41 29 0 TRUE 0.52
non-small cell lung cancer KRAS_G12D IGF1R 100 23 >65yrs -1.09 -3.86 0.83 1139.98 1.00 2007 99 22 1 TRUE 0.43
colorectal cancer KRAS_G12D IGF1R 302 80 Age:overall -0.40 -1.25 0.37 1068.98 1.00 1920 294 72 8 TRUE 0.47
non-small cell lung cancer KRAS_G12D IGF1R 141 52 Age:overall -1.31 -4.59 0.95 1193.02 1.00 3252 140 51 1 TRUE 0.46
cancer of unknown primary KRAS_G12D KEAP1 21 31 50-65yrs -5.40 -11.63 -1.24 789.16 1.01 262 21 31 0 FALSE 1.33
cancer of unknown primary KRAS_G12D KEAP1 26 32 >65yrs -5.40 -11.49 -1.26 775.41 1.01 306 26 32 0 FALSE 1.30
non-small cell lung cancer KRAS_G12D KEAP1 8 22 40-50yrs -0.10 -0.77 0.56 1012.17 1.00 162 7 21 1 FALSE 0.12
non-small cell lung cancer KRAS_G12D KEAP1 41 203 50-65yrs -0.05 -0.60 0.54 882.40 1.01 1088 33 195 8 FALSE 0.07
non-small cell lung cancer KRAS_G12D KEAP1 100 312 >65yrs -0.14 -0.65 0.34 1425.57 1.00 1742 88 300 12 FALSE 0.25
cancer of unknown primary KRAS_G12D KEAP1 47 63 Age:overall -5.35 -11.32 -1.11 781.23 1.01 568 47 63 0 FALSE 1.32
non-small cell lung cancer KRAS_G12D KEAP1 149 537 Age:overall -0.10 -0.68 0.46 1434.72 1.00 2992 128 516 21 FALSE 0.14
colorectal cancer KRAS_G12D KDM5C 127 24 50-65yrs -0.21 -1.21 0.70 1034.76 1.00 822 124 21 3 FALSE 0.17
colorectal cancer KRAS_G12D KDM5C 84 26 >65yrs -0.20 -1.21 0.72 908.43 1.00 546 81 23 3 FALSE 0.16
non-small cell lung cancer KRAS_G12D KDM5C 41 43 50-65yrs -0.73 -4.47 0.83 975.16 1.00 1234 41 43 0 FALSE 0.20
non-small cell lung cancer KRAS_G12D KDM5C 101 59 >65yrs 0.25 -0.77 1.23 760.40 1.00 1975 96 54 5 FALSE 0.20
uterine cancer KRAS_G12D KDM5C 25 32 50-65yrs -0.05 -1.54 1.14 1041.85 1.00 467 23 30 2 FALSE 0.03
uterine cancer KRAS_G12D KDM5C 18 32 >65yrs -0.14 -1.78 1.09 898.56 1.00 435 17 31 1 FALSE 0.07
colorectal cancer KRAS_G12D KDM5C 211 50 Age:overall -0.22 -1.35 0.83 952.94 1.00 1368 205 44 6 FALSE 0.15
non-small cell lung cancer KRAS_G12D KDM5C 142 102 Age:overall -0.19 -2.56 1.30 1520.22 1.00 3209 137 97 5 FALSE 0.07
uterine cancer KRAS_G12D KDM5C 43 64 Age:overall -0.10 -1.92 1.24 1090.11 1.00 902 40 61 3 FALSE 0.05
cancer of unknown primary KRAS_G12D CDKN2A 21 20 50-65yrs -0.10 -1.60 1.06 1337.07 1.00 277 20 19 1 TRUE 0.05
cancer of unknown primary KRAS_G12D CDKN2A 26 43 >65yrs 0.15 -1.00 1.14 1380.29 1.00 304 22 39 4 TRUE 0.11
non-small cell lung cancer KRAS_G12D CDKN2A 8 18 40-50yrs -0.09 -1.09 1.04 1302.94 1.00 180 6 16 2 TRUE 0.06
non-small cell lung cancer KRAS_G12D CDKN2A 42 114 50-65yrs -0.42 -1.34 0.36 1380.63 1.00 1227 41 113 1 TRUE 0.46
non-small cell lung cancer KRAS_G12D CDKN2A 104 141 >65yrs -0.23 -0.99 0.50 1304.04 1.00 1950 98 135 6 TRUE 0.26
pancreatic cancer KRAS_G12D CDKN2A 40 11 40-50yrs 0.30 -0.42 0.98 1642.23 1.00 79 36 7 4 TRUE 0.40
pancreatic cancer KRAS_G12D CDKN2A 209 104 50-65yrs 0.55 0.19 0.94 1097.69 1.00 375 162 57 47 TRUE 2.29
pancreatic cancer KRAS_G12D CDKN2A 265 175 >65yrs 0.42 0.11 0.75 1288.97 1.00 424 195 105 70 TRUE 2.01
cancer of unknown primary KRAS_G12D CDKN2A 47 63 Age:overall 0.02 -1.47 1.31 1416.26 1.00 581 42 58 5 TRUE 0.01
non-small cell lung cancer KRAS_G12D CDKN2A 154 273 Age:overall -0.24 -1.09 0.56 1422.58 1.00 3357 145 264 9 TRUE 0.24
pancreatic cancer KRAS_G12D CDKN2A 514 290 Age:overall 0.42 -0.15 0.95 1256.31 1.00 878 393 169 121 TRUE 0.88
colorectal cancer KRAS_G12D EPHB1 35 13 <40yrs -1.11 -2.36 -0.08 558.49 1.00 171 34 12 1 FALSE 1.25
colorectal cancer KRAS_G12D EPHB1 127 31 50-65yrs -1.16 -2.42 -0.19 518.05 1.00 811 126 30 1 FALSE 1.38
colorectal cancer KRAS_G12D EPHB1 84 28 >65yrs -1.09 -2.29 -0.13 582.39 1.00 541 82 26 2 FALSE 1.29
non-small cell lung cancer KRAS_G12D EPHB1 41 54 50-65yrs -0.67 -2.40 0.72 1113.54 1.00 1231 39 52 2 FALSE 0.40
non-small cell lung cancer KRAS_G12D EPHB1 100 99 >65yrs -1.16 -2.92 0.08 1004.28 1.00 1935 99 98 1 FALSE 0.88
colorectal cancer KRAS_G12D EPHB1 246 72 Age:overall -1.12 -2.35 -0.17 523.41 1.00 1523 242 68 4 FALSE 1.36
non-small cell lung cancer KRAS_G12D EPHB1 141 153 Age:overall -0.91 -2.66 0.47 1136.76 1.00 3166 138 150 3 FALSE 0.58
colorectal cancer KRAS_G12D IRS2 35 13 <40yrs -0.05 -0.82 0.60 154.08 1.02 172 33 11 2 FALSE 0.05
colorectal cancer KRAS_G12D IRS2 56 19 40-50yrs -0.07 -0.85 0.57 138.78 1.02 379 54 17 2 FALSE 0.07
colorectal cancer KRAS_G12D IRS2 127 30 50-65yrs -0.08 -0.83 0.50 127.24 1.03 817 124 27 3 FALSE 0.09
colorectal cancer KRAS_G12D IRS2 84 25 >65yrs -0.05 -0.81 0.58 147.03 1.02 547 80 21 4 FALSE 0.05
non-small cell lung cancer KRAS_G12D IRS2 41 25 50-65yrs -5.02 -11.92 -0.66 1413.58 1.00 1249 41 25 0 FALSE 1.06
non-small cell lung cancer KRAS_G12D IRS2 100 55 >65yrs -5.07 -12.20 -0.93 1420.40 1.00 1976 100 55 0 FALSE 1.12
uterine cancer KRAS_G12D IRS2 25 32 50-65yrs -1.90 -5.79 0.31 267.44 1.02 460 25 32 0 FALSE 0.69
uterine cancer KRAS_G12D IRS2 18 34 >65yrs -1.58 -5.00 0.64 198.00 1.02 431 17 33 1 FALSE 0.59
colorectal cancer KRAS_G12D IRS2 302 87 Age:overall -0.06 -0.81 0.52 131.56 1.03 1915 291 76 11 FALSE 0.07
non-small cell lung cancer KRAS_G12D IRS2 141 80 Age:overall -4.96 -11.79 -0.65 1421.60 1.00 3225 141 80 0 FALSE 1.08
uterine cancer KRAS_G12D IRS2 43 66 Age:overall -1.73 -5.24 0.40 232.79 1.01 891 42 65 1 FALSE 0.65
colorectal cancer KRAS_G12D FANCA 35 11 <40yrs -0.15 -1.07 0.65 1038.84 1.00 172 34 10 1 TRUE 0.14
colorectal cancer KRAS_G12D FANCA 56 11 40-50yrs -0.12 -0.96 0.71 1099.93 1.00 386 54 9 2 TRUE 0.11
colorectal cancer KRAS_G12D FANCA 127 31 50-65yrs -0.14 -0.98 0.61 1160.15 1.00 819 123 27 4 TRUE 0.13
colorectal cancer KRAS_G12D FANCA 84 12 >65yrs -0.18 -1.09 0.59 1189.94 1.00 554 83 11 1 TRUE 0.18
non-small cell lung cancer KRAS_G12D FANCA 41 29 50-65yrs 0.19 -1.38 1.33 1468.57 1.00 1246 40 28 1 TRUE 0.11
non-small cell lung cancer KRAS_G12D FANCA 100 36 >65yrs 0.35 -0.90 1.38 1236.92 1.00 1997 97 33 3 TRUE 0.27
colorectal cancer KRAS_G12D FANCA 302 65 Age:overall -0.15 -1.02 0.60 1110.34 1.00 1931 294 57 8 TRUE 0.15
non-small cell lung cancer KRAS_G12D FANCA 141 65 Age:overall 0.26 -1.29 1.58 1395.15 1.00 3243 137 61 4 TRUE 0.14
non-small cell lung cancer KRAS_G12D IL7R 41 38 50-65yrs -1.25 -4.33 0.58 708.08 1.00 1241 41 38 0 FALSE 0.49
non-small cell lung cancer KRAS_G12D IL7R 100 49 >65yrs -0.84 -2.84 0.65 281.45 1.00 1985 98 47 2 FALSE 0.46
non-small cell lung cancer KRAS_G12D IL7R 141 87 Age:overall -1.02 -3.23 0.74 489.72 1.00 3226 139 85 2 FALSE 0.49
uterine cancer KRAS_G12D PPP2R1A 25 54 50-65yrs -0.46 -2.04 0.89 1367.07 1.00 439 22 51 3 FALSE 0.26
uterine cancer KRAS_G12D PPP2R1A 18 100 >65yrs -2.38 -7.06 -0.23 1327.84 1.00 367 18 100 0 FALSE 0.76
uterine cancer KRAS_G12D PPP2R1A 43 154 Age:overall -1.32 -4.25 0.96 1516.75 1.00 806 40 151 3 FALSE 0.49
colorectal cancer KRAS_G12D PIK3CB 54 21 40-50yrs -1.82 -3.90 -0.42 1159.89 1.00 366 54 21 0 FALSE 1.40
colorectal cancer KRAS_G12D PIK3CB 122 17 50-65yrs -1.68 -3.62 -0.26 1213.18 1.00 806 121 16 1 FALSE 1.33
colorectal cancer KRAS_G12D PIK3CB 81 22 >65yrs -1.69 -3.61 -0.31 1108.82 1.00 534 80 21 1 FALSE 1.37
colorectal cancer KRAS_G12D PIK3CB 257 60 Age:overall -1.72 -3.62 -0.40 1156.83 1.00 1706 255 58 2 FALSE 1.44
colorectal cancer KRAS_G12D ERBB3 35 13 <40yrs -0.11 -0.81 0.55 1076.62 1.00 173 33 11 2 TRUE 0.13
colorectal cancer KRAS_G12D ERBB3 56 14 40-50yrs -0.18 -0.91 0.48 1177.02 1.00 383 55 13 1 TRUE 0.22
colorectal cancer KRAS_G12D ERBB3 128 48 50-65yrs -0.12 -0.76 0.44 1149.31 1.01 801 122 42 6 TRUE 0.17
colorectal cancer KRAS_G12D ERBB3 84 47 >65yrs -0.10 -0.71 0.49 1022.95 1.00 531 78 41 6 TRUE 0.12
uterine cancer KRAS_G12D ERBB3 25 45 50-65yrs -1.55 -4.66 0.54 338.43 1.00 450 24 44 1 TRUE 0.65
uterine cancer KRAS_G12D ERBB3 18 24 >65yrs -1.84 -5.52 0.52 359.33 1.00 432 18 24 0 TRUE 0.65
colorectal cancer KRAS_G12D ERBB3 303 122 Age:overall -0.13 -0.75 0.43 1106.56 1.01 1888 288 107 15 TRUE 0.17
uterine cancer KRAS_G12D ERBB3 43 69 Age:overall -1.66 -4.88 0.49 351.40 1.00 882 42 68 1 TRUE 0.64
colorectal cancer KRAS_G12D SMAD4 39 33 <40yrs -0.03 -0.40 0.31 940.24 1.00 172 34 28 5 TRUE 0.07
colorectal cancer KRAS_G12D SMAD4 63 68 40-50yrs -0.03 -0.39 0.32 804.96 1.01 371 54 59 9 TRUE 0.07
colorectal cancer KRAS_G12D SMAD4 149 151 50-65yrs -0.02 -0.36 0.30 820.76 1.00 805 126 128 23 TRUE 0.05
colorectal cancer KRAS_G12D SMAD4 96 108 >65yrs -0.05 -0.42 0.28 719.18 1.01 541 85 97 11 TRUE 0.10
non-small cell lung cancer KRAS_G12D SMAD4 42 45 50-65yrs -0.34 -2.01 0.96 1086.05 1.01 1292 40 43 2 TRUE 0.18
non-small cell lung cancer KRAS_G12D SMAD4 104 64 >65yrs -0.75 -2.52 0.48 809.27 1.01 2016 103 63 1 TRUE 0.47
pancreatic cancer KRAS_G12D SMAD4 40 18 40-50yrs -0.07 -0.40 0.27 1150.49 1.00 73 35 13 5 TRUE 0.16
pancreatic cancer KRAS_G12D SMAD4 205 113 50-65yrs -0.04 -0.32 0.25 832.83 1.00 356 167 75 38 TRUE 0.10
pancreatic cancer KRAS_G12D SMAD4 262 139 >65yrs -0.07 -0.35 0.22 969.30 1.00 430 219 96 43 TRUE 0.20
colorectal cancer KRAS_G12D SMAD4 347 360 Age:overall -0.03 -0.38 0.28 811.38 1.01 1889 299 312 48 TRUE 0.07
non-small cell lung cancer KRAS_G12D SMAD4 146 109 Age:overall -0.52 -2.21 0.92 1090.76 1.00 3308 143 106 3 TRUE 0.28
pancreatic cancer KRAS_G12D SMAD4 507 270 Age:overall -0.06 -0.36 0.23 1012.24 1.00 859 421 184 86 TRUE 0.16
colorectal cancer KRAS_G12D ATM 38 24 <40yrs -0.36 -0.92 0.20 1174.94 1.00 186 35 21 3 TRUE 0.68
colorectal cancer KRAS_G12D ATM 63 33 40-50yrs -0.47 -1.11 0.09 1363.94 1.00 398 62 32 1 TRUE 0.89
colorectal cancer KRAS_G12D ATM 149 87 50-65yrs -0.29 -0.80 0.20 1385.28 1.00 868 137 75 12 TRUE 0.62
colorectal cancer KRAS_G12D ATM 97 87 >65yrs -0.38 -0.93 0.10 1444.38 1.00 564 89 79 8 TRUE 0.85
non-small cell lung cancer KRAS_G12D ATM 42 100 50-65yrs 0.11 -0.83 0.88 1416.66 1.00 1244 39 97 3 TRUE 0.10
non-small cell lung cancer KRAS_G12D ATM 106 179 >65yrs 0.29 -0.32 0.83 1485.45 1.00 1933 94 167 12 TRUE 0.47
uterine cancer KRAS_G12D ATM 11 24 40-50yrs 0.07 -1.11 1.22 1544.62 1.00 73 8 21 3 TRUE 0.04
uterine cancer KRAS_G12D ATM 26 84 50-65yrs -0.41 -1.58 0.58 1264.65 1.00 507 24 82 2 TRUE 0.33
uterine cancer KRAS_G12D ATM 19 50 >65yrs -0.12 -1.38 0.96 1519.34 1.00 468 17 48 2 TRUE 0.07
colorectal cancer KRAS_G12D ATM 347 231 Age:overall -0.38 -0.87 0.10 1269.70 1.00 2016 323 207 24 TRUE 0.92
non-small cell lung cancer KRAS_G12D ATM 148 279 Age:overall 0.20 -0.86 1.05 1312.30 1.00 3177 133 264 15 TRUE 0.17
uterine cancer KRAS_G12D ATM 56 158 Age:overall -0.15 -1.36 0.97 1422.80 1.00 1048 49 151 7 TRUE 0.10
cancer of unknown primary KRAS_G12D RB1 22 25 50-65yrs -0.48 -1.99 0.82 784.33 1.00 275 20 23 2 TRUE 0.31
cancer of unknown primary KRAS_G12D RB1 26 39 >65yrs -0.69 -2.21 0.52 791.41 1.01 305 25 38 1 TRUE 0.49
colorectal cancer KRAS_G12D RB1 63 15 40-50yrs -0.72 -1.97 0.24 337.15 1.01 409 63 15 0 TRUE 0.66
colorectal cancer KRAS_G12D RB1 147 20 50-65yrs -0.68 -1.80 0.23 202.27 1.01 913 146 19 1 TRUE 0.69
colorectal cancer KRAS_G12D RB1 96 24 >65yrs -0.55 -1.49 0.34 89.28 1.03 609 92 20 4 TRUE 0.55
non-small cell lung cancer KRAS_G12D RB1 42 82 50-65yrs -0.64 -1.86 0.43 1256.55 1.00 1253 40 80 2 TRUE 0.55
non-small cell lung cancer KRAS_G12D RB1 104 131 >65yrs -0.75 -1.93 0.14 1183.91 1.00 1954 101 128 3 TRUE 0.83
uterine cancer KRAS_G12D RB1 26 48 50-65yrs -2.03 -5.78 0.02 950.26 1.00 514 26 48 0 TRUE 0.81
uterine cancer KRAS_G12D RB1 19 35 >65yrs -1.62 -4.53 0.40 1066.64 1.00 478 18 34 1 TRUE 0.73
cancer of unknown primary KRAS_G12D RB1 48 64 Age:overall -0.58 -2.13 0.83 776.95 1.00 580 45 61 3 TRUE 0.36
colorectal cancer KRAS_G12D RB1 306 59 Age:overall -0.65 -1.70 0.23 154.16 1.02 1931 301 54 5 TRUE 0.69
non-small cell lung cancer KRAS_G12D RB1 146 213 Age:overall -0.70 -1.99 0.44 1427.37 1.00 3207 141 208 5 TRUE 0.57
uterine cancer KRAS_G12D RB1 45 83 Age:overall -1.77 -4.96 0.43 1002.54 1.00 992 44 82 1 TRUE 0.74
cancer of unknown primary KRAS_G12D KMT2D 21 40 50-65yrs -0.07 -1.18 0.90 1134.97 1.00 263 19 38 2 FALSE 0.05
cancer of unknown primary KRAS_G12D KMT2D 26 69 >65yrs 0.15 -0.73 0.95 1394.53 1.00 291 20 63 6 FALSE 0.14
colorectal cancer KRAS_G12D KMT2D 38 41 <40yrs -0.15 -0.82 0.52 1422.14 1.00 160 31 34 7 FALSE 0.18
colorectal cancer KRAS_G12D KMT2D 60 52 40-50yrs -0.05 -0.69 0.64 1528.05 1.00 365 51 43 9 FALSE 0.05
colorectal cancer KRAS_G12D KMT2D 129 122 50-65yrs -0.46 -1.00 0.04 1390.09 1.00 766 119 112 10 FALSE 1.09
colorectal cancer KRAS_G12D KMT2D 89 173 >65yrs -0.56 -1.12 -0.07 1249.27 1.00 479 77 161 12 FALSE 1.42
non-small cell lung cancer KRAS_G12D KMT2D 41 130 50-65yrs -1.48 -3.04 -0.34 1468.43 1.00 1167 40 129 1 FALSE 1.47
non-small cell lung cancer KRAS_G12D KMT2D 101 188 >65yrs -1.36 -2.61 -0.35 1230.96 1.00 1866 98 185 3 FALSE 1.73
pancreatic cancer KRAS_G12D KMT2D 200 27 50-65yrs 0.21 -0.52 0.62 8.50 1.18 399 192 19 8 FALSE 0.27
pancreatic cancer KRAS_G12D KMT2D 256 32 >65yrs 0.30 -0.33 0.78 18.26 1.12 490 242 18 14 FALSE 0.51
uterine cancer KRAS_G12D KMT2D 11 26 40-50yrs 0.04 -0.88 1.06 1343.07 1.00 67 7 22 4 FALSE 0.03
uterine cancer KRAS_G12D KMT2D 27 125 50-65yrs -0.16 -0.94 0.61 1265.98 1.00 411 21 119 6 FALSE 0.16
uterine cancer KRAS_G12D KMT2D 18 108 >65yrs -0.54 -1.93 0.36 1404.29 1.00 385 17 107 1 FALSE 0.47
cancer of unknown primary KRAS_G12D KMT2D 47 109 Age:overall 0.04 -1.13 1.07 1357.43 1.00 554 39 101 8 FALSE 0.03
colorectal cancer KRAS_G12D KMT2D 316 388 Age:overall -0.30 -0.83 0.26 1448.14 1.00 1770 278 350 38 FALSE 0.55
non-small cell lung cancer KRAS_G12D KMT2D 142 318 Age:overall -1.42 -3.02 -0.22 1339.17 1.00 3033 138 314 4 FALSE 1.37
pancreatic cancer KRAS_G12D KMT2D 456 59 Age:overall 0.26 -0.52 0.82 21.44 1.09 889 434 37 22 FALSE 0.32
uterine cancer KRAS_G12D KMT2D 56 259 Age:overall -0.21 -1.14 0.67 1383.96 1.00 863 45 248 11 FALSE 0.19
colorectal cancer KRAS_G12D TSC2 36 14 <40yrs 0.05 -0.68 0.81 1269.42 1.00 173 32 10 4 TRUE 0.04
colorectal cancer KRAS_G12D TSC2 56 19 40-50yrs -0.08 -0.84 0.59 1251.69 1.00 379 54 17 2 TRUE 0.08
colorectal cancer KRAS_G12D TSC2 128 36 50-65yrs -0.10 -0.82 0.53 1483.92 1.00 813 124 32 4 TRUE 0.11
colorectal cancer KRAS_G12D TSC2 85 46 >65yrs -0.08 -0.76 0.55 1336.37 1.00 534 80 41 5 TRUE 0.08
non-small cell lung cancer KRAS_G12D TSC2 41 23 50-65yrs -1.74 -5.54 0.45 601.41 1.01 1253 41 23 0 TRUE 0.65
non-small cell lung cancer KRAS_G12D TSC2 100 44 >65yrs -1.56 -4.44 0.33 540.32 1.01 1987 99 43 1 TRUE 0.69
uterine cancer KRAS_G12D TSC2 26 33 50-65yrs 0.29 -0.98 1.40 880.18 1.00 465 23 30 3 TRUE 0.20
uterine cancer KRAS_G12D TSC2 18 34 >65yrs 0.10 -1.44 1.27 1060.31 1.00 430 17 33 1 TRUE 0.06
colorectal cancer KRAS_G12D TSC2 305 115 Age:overall -0.05 -0.73 0.55 1308.95 1.00 1899 290 100 15 TRUE 0.06
non-small cell lung cancer KRAS_G12D TSC2 141 67 Age:overall -1.62 -4.84 0.46 559.14 1.01 3240 140 66 1 TRUE 0.64
uterine cancer KRAS_G12D TSC2 44 67 Age:overall 0.19 -1.34 1.47 975.41 1.00 895 40 63 4 TRUE 0.10
cancer of unknown primary KRAS_G12D APC 22 21 50-65yrs 0.60 -0.52 1.53 1293.62 1.00 278 20 19 2 TRUE 0.61
cancer of unknown primary KRAS_G12D APC 28 30 >65yrs 0.75 -0.21 1.63 1269.41 1.00 318 23 25 5 TRUE 0.97
colorectal cancer KRAS_G12D APC 55 246 <40yrs 0.06 -0.19 0.31 1278.19 1.00 76 13 204 42 TRUE 0.20
colorectal cancer KRAS_G12D APC 90 494 40-50yrs 0.04 -0.20 0.28 1275.04 1.00 147 22 426 68 TRUE 0.14
colorectal cancer KRAS_G12D APC 215 1094 50-65yrs 0.04 -0.19 0.27 1328.63 1.00 313 57 936 158 TRUE 0.14
colorectal cancer KRAS_G12D APC 130 704 >65yrs 0.05 -0.20 0.28 1353.88 1.00 231 32 606 98 TRUE 0.15
non-small cell lung cancer KRAS_G12D APC 42 60 50-65yrs 0.07 -1.15 1.00 1299.58 1.00 1277 40 58 2 TRUE 0.05
non-small cell lung cancer KRAS_G12D APC 104 87 >65yrs 0.13 -0.74 0.93 1224.74 1.00 2002 99 82 5 TRUE 0.12
uterine cancer KRAS_G12D APC 12 30 40-50yrs 0.41 -0.80 1.59 1458.15 1.00 77 7 25 5 TRUE 0.29
uterine cancer KRAS_G12D APC 26 45 50-65yrs -0.68 -2.61 0.76 1496.98 1.00 526 25 44 1 TRUE 0.38
uterine cancer KRAS_G12D APC 19 42 >65yrs -1.15 -3.80 0.56 1467.31 1.00 475 19 42 0 TRUE 0.51
cancer of unknown primary KRAS_G12D APC 50 51 Age:overall 0.66 -0.52 1.64 1343.72 1.00 596 43 44 7 TRUE 0.55
colorectal cancer KRAS_G12D APC 490 2538 Age:overall 0.05 -0.19 0.27 1281.06 1.00 767 124 2172 366 TRUE 0.16
non-small cell lung cancer KRAS_G12D APC 146 147 Age:overall 0.12 -1.03 1.18 1243.09 1.00 3279 139 140 7 TRUE 0.07
uterine cancer KRAS_G12D APC 57 117 Age:overall -0.45 -2.33 1.09 1534.11 1.00 1078 51 111 6 TRUE 0.22
colorectal cancer KRAS_G12D ERBB2 38 13 <40yrs -0.56 -1.39 0.15 699.79 1.00 187 36 11 2 TRUE 0.81
colorectal cancer KRAS_G12D ERBB2 63 13 40-50yrs -0.59 -1.47 0.11 714.78 1.00 410 62 12 1 TRUE 0.85
colorectal cancer KRAS_G12D ERBB2 147 49 50-65yrs -0.57 -1.40 0.12 724.08 1.00 889 142 44 5 TRUE 0.87
colorectal cancer KRAS_G12D ERBB2 95 29 >65yrs -0.61 -1.46 0.08 635.70 1.00 600 94 28 1 TRUE 0.94
non-small cell lung cancer KRAS_G12D ERBB2 42 53 50-65yrs -2.25 -5.18 -0.04 634.10 1.00 1280 42 53 0 TRUE 1.03
non-small cell lung cancer KRAS_G12D ERBB2 104 68 >65yrs -2.07 -4.86 0.00 581.84 1.01 2015 103 67 1 TRUE 1.07
uterine cancer KRAS_G12D ERBB2 26 36 50-65yrs -4.93 -11.86 -0.45 1039.35 1.00 519 26 36 0 TRUE 1.01
uterine cancer KRAS_G12D ERBB2 19 14 >65yrs -4.85 -11.93 -0.24 1125.65 1.00 488 19 14 0 TRUE 0.97
colorectal cancer KRAS_G12D ERBB2 343 104 Age:overall -0.58 -1.40 0.09 662.76 1.00 2086 334 95 9 TRUE 0.90
non-small cell lung cancer KRAS_G12D ERBB2 146 121 Age:overall -2.13 -4.94 0.12 627.40 1.00 3295 145 120 1 TRUE 1.05
uterine cancer KRAS_G12D ERBB2 45 50 Age:overall -4.77 -11.35 -0.32 1057.14 1.00 1007 45 50 0 TRUE 1.01
colorectal cancer KRAS_G12D JAK1 36 16 <40yrs -0.23 -1.25 0.76 1431.28 1.00 175 33 13 3 TRUE 0.19
colorectal cancer KRAS_G12D JAK1 56 13 40-50yrs -0.55 -1.89 0.46 1325.34 1.00 384 56 13 0 TRUE 0.46
colorectal cancer KRAS_G12D JAK1 127 20 50-65yrs -0.53 -1.63 0.37 1578.66 1.00 823 126 19 1 TRUE 0.52
colorectal cancer KRAS_G12D JAK1 86 26 >65yrs -0.23 -1.17 0.66 1424.90 1.00 544 82 22 4 TRUE 0.20
non-small cell lung cancer KRAS_G12D JAK1 41 15 50-65yrs -4.88 -11.54 -0.26 720.99 1.00 1259 41 15 0 TRUE 1.06
non-small cell lung cancer KRAS_G12D JAK1 100 34 >65yrs -4.92 -11.61 -0.46 762.29 1.00 1997 100 34 0 TRUE 1.07
uterine cancer KRAS_G12D JAK1 12 19 40-50yrs 1.21 0.21 2.27 1427.86 1.00 70 6 13 6 TRUE 1.67
uterine cancer KRAS_G12D JAK1 26 69 50-65yrs 0.48 -0.44 1.30 1481.46 1.00 444 22 65 4 TRUE 0.54
uterine cancer KRAS_G12D JAK1 18 51 >65yrs 0.60 -0.42 1.50 1214.71 1.00 421 15 48 3 TRUE 0.68
colorectal cancer KRAS_G12D JAK1 305 75 Age:overall -0.38 -1.32 0.45 1446.46 1.00 1926 297 67 8 TRUE 0.41
non-small cell lung cancer KRAS_G12D JAK1 141 49 Age:overall -4.81 -11.35 -0.22 808.41 1.00 3256 141 49 0 TRUE 1.05
uterine cancer KRAS_G12D JAK1 56 139 Age:overall 0.74 -0.31 1.73 1489.03 1.00 935 43 126 13 TRUE 0.86
uterine cancer KRAS_G12D CCND1 25 32 50-65yrs 0.58 -0.63 1.58 1500.14 1.00 458 23 30 2 TRUE 0.51
uterine cancer KRAS_G12D CCND1 18 27 >65yrs 0.77 -0.47 1.83 1343.75 1.00 432 15 24 3 TRUE 0.73
uterine cancer KRAS_G12D CCND1 43 59 Age:overall 0.68 -0.60 1.80 1538.01 1.00 890 38 54 5 TRUE 0.58
colorectal cancer KRAS_G12D ARID2 56 21 40-50yrs -0.22 -0.99 0.58 1425.39 1.00 379 53 18 3 FALSE 0.23
colorectal cancer KRAS_G12D ARID2 127 36 50-65yrs -0.38 -1.28 0.32 1350.01 1.00 812 125 34 2 FALSE 0.45
colorectal cancer KRAS_G12D ARID2 84 44 >65yrs -0.18 -0.89 0.53 1200.43 1.00 531 78 38 6 FALSE 0.20
non-small cell lung cancer KRAS_G12D ARID2 41 71 50-65yrs -0.46 -1.72 0.62 240.74 1.01 1207 40 70 1 FALSE 0.34
non-small cell lung cancer KRAS_G12D ARID2 100 105 >65yrs -0.24 -1.35 0.62 75.56 1.04 1939 95 100 5 FALSE 0.21
uterine cancer KRAS_G12D ARID2 26 40 50-65yrs -0.08 -1.64 1.14 1294.28 1.00 461 24 38 2 FALSE 0.04
uterine cancer KRAS_G12D ARID2 18 19 >65yrs -0.04 -1.89 1.39 1443.12 1.00 441 17 18 1 FALSE 0.01
colorectal cancer KRAS_G12D ARID2 267 101 Age:overall -0.27 -1.01 0.47 1319.11 1.00 1722 256 90 11 FALSE 0.33
non-small cell lung cancer KRAS_G12D ARID2 141 176 Age:overall -0.34 -1.50 0.83 211.63 1.01 3146 135 170 6 FALSE 0.23
uterine cancer KRAS_G12D ARID2 44 59 Age:overall -0.06 -1.84 1.42 1491.88 1.00 902 41 56 3 FALSE 0.03
colorectal cancer KRAS_G12D SOX17 54 11 40-50yrs 0.47 -0.43 1.40 1605.32 1.00 374 51 8 3 FALSE 0.49
colorectal cancer KRAS_G12D SOX17 122 32 50-65yrs 0.40 -0.40 1.11 1396.52 1.00 793 116 26 6 FALSE 0.54
colorectal cancer KRAS_G12D SOX17 82 47 >65yrs 0.32 -0.40 0.99 1351.21 1.00 516 75 40 7 FALSE 0.42
non-small cell lung cancer KRAS_G12D SOX17 41 26 50-65yrs -0.82 -3.54 0.82 1146.31 1.00 1243 41 26 0 FALSE 0.32
non-small cell lung cancer KRAS_G12D SOX17 100 32 >65yrs -0.34 -2.17 0.98 1297.33 1.00 1992 98 30 2 FALSE 0.17
colorectal cancer KRAS_G12D SOX17 258 90 Age:overall 0.40 -0.42 1.14 1569.76 1.00 1683 242 74 16 FALSE 0.48
non-small cell lung cancer KRAS_G12D SOX17 141 58 Age:overall -0.58 -2.84 1.02 1342.24 1.00 3235 139 56 2 FALSE 0.26
colorectal cancer KRAS_G12D MTOR 37 15 <40yrs -0.12 -0.78 0.50 1166.90 1.00 172 34 12 3 TRUE 0.15
colorectal cancer KRAS_G12D MTOR 56 26 40-50yrs -0.18 -0.84 0.37 1154.88 1.00 375 54 24 2 TRUE 0.25
colorectal cancer KRAS_G12D MTOR 128 54 50-65yrs -0.05 -0.64 0.56 1157.35 1.00 803 117 43 11 TRUE 0.06
colorectal cancer KRAS_G12D MTOR 84 45 >65yrs -0.26 -1.05 0.35 1032.68 1.00 527 83 44 1 TRUE 0.33
non-small cell lung cancer KRAS_G12D MTOR 41 39 50-65yrs -1.38 -4.00 0.34 1130.86 1.00 1236 41 39 0 TRUE 0.64
non-small cell lung cancer KRAS_G12D MTOR 100 70 >65yrs -1.02 -2.75 0.32 1156.71 1.00 1962 98 68 2 TRUE 0.70
uterine cancer KRAS_G12D MTOR 10 13 40-50yrs 0.75 -0.42 1.91 1384.57 1.00 74 7 10 3 TRUE 0.71
uterine cancer KRAS_G12D MTOR 25 35 50-65yrs 0.42 -0.65 1.36 1182.88 1.00 462 23 33 2 TRUE 0.38
uterine cancer KRAS_G12D MTOR 18 39 >65yrs 0.45 -0.71 1.38 1407.92 1.00 425 16 37 2 TRUE 0.41
colorectal cancer KRAS_G12D MTOR 305 140 Age:overall -0.15 -0.75 0.38 1172.30 1.00 1877 288 123 17 TRUE 0.22
non-small cell lung cancer KRAS_G12D MTOR 141 109 Age:overall -1.16 -3.27 0.56 1251.61 1.00 3198 139 107 2 TRUE 0.62
uterine cancer KRAS_G12D MTOR 53 87 Age:overall 0.53 -0.57 1.52 1227.59 1.00 961 46 80 7 TRUE 0.50
non-small cell lung cancer KRAS_G12D RFWD2 41 25 50-65yrs -0.66 -3.27 0.92 665.86 1.01 1243 41 25 0 FALSE 0.24
non-small cell lung cancer KRAS_G12D RFWD2 100 31 >65yrs -0.28 -2.16 1.12 1023.35 1.01 1992 98 29 2 FALSE 0.14
non-small cell lung cancer KRAS_G12D RFWD2 141 56 Age:overall -0.45 -2.71 1.13 859.31 1.01 3235 139 54 2 FALSE 0.18
colorectal cancer KRAS_G12D IRS1 54 17 40-50yrs -0.54 -1.75 0.82 631.72 1.00 372 50 13 4 FALSE 0.41
colorectal cancer KRAS_G12D IRS1 123 34 50-65yrs -0.85 -1.96 0.02 659.20 1.00 790 121 32 2 FALSE 0.99
colorectal cancer KRAS_G12D IRS1 81 36 >65yrs -1.05 -2.68 -0.08 873.59 1.00 519 81 36 0 FALSE 0.82
non-small cell lung cancer KRAS_G12D IRS1 41 28 50-65yrs -4.90 -11.69 -0.50 1019.30 1.00 1240 41 28 0 FALSE 0.99
non-small cell lung cancer KRAS_G12D IRS1 100 42 >65yrs -4.91 -11.61 -0.72 1132.80 1.00 1982 100 42 0 FALSE 1.03
colorectal cancer KRAS_G12D IRS1 258 87 Age:overall -0.82 -1.90 0.08 654.16 1.00 1681 252 81 6 FALSE 0.86
non-small cell lung cancer KRAS_G12D IRS1 141 70 Age:overall -4.79 -11.53 -0.43 1129.38 1.00 3222 141 70 0 FALSE 1.01
cancer of unknown primary KRAS_G12D NOTCH1 22 17 50-65yrs -0.41 -2.39 1.21 1176.45 1.00 281 20 15 2 TRUE 0.19
cancer of unknown primary KRAS_G12D NOTCH1 26 27 >65yrs -1.22 -4.50 0.50 1063.26 1.00 316 26 27 0 TRUE 0.43
colorectal cancer KRAS_G12D NOTCH1 38 18 <40yrs -0.41 -1.18 0.28 1489.79 1.00 187 36 16 2 TRUE 0.59
colorectal cancer KRAS_G12D NOTCH1 64 27 40-50yrs -0.36 -1.03 0.33 1500.13 1.00 405 60 23 4 TRUE 0.52
colorectal cancer KRAS_G12D NOTCH1 148 55 50-65yrs -0.50 -1.17 0.09 1366.95 1.00 886 144 51 4 TRUE 0.90
colorectal cancer KRAS_G12D NOTCH1 97 72 >65yrs -0.40 -1.01 0.18 1465.79 1.00 577 90 65 7 TRUE 0.71
non-small cell lung cancer KRAS_G12D NOTCH1 42 45 50-65yrs -0.89 -3.87 0.60 896.39 1.00 1287 42 45 0 TRUE 0.36
non-small cell lung cancer KRAS_G12D NOTCH1 104 77 >65yrs -0.29 -1.53 0.76 794.61 1.01 2010 100 73 4 TRUE 0.22
uterine cancer KRAS_G12D NOTCH1 26 43 50-65yrs -0.86 -2.44 0.77 18.76 1.12 522 24 41 2 TRUE 0.46
uterine cancer KRAS_G12D NOTCH1 19 39 >65yrs -1.23 -3.81 0.41 92.19 1.04 474 19 39 0 TRUE 0.55
cancer of unknown primary KRAS_G12D NOTCH1 48 44 Age:overall -0.79 -3.36 0.94 1366.29 1.00 597 46 42 2 TRUE 0.31
colorectal cancer KRAS_G12D NOTCH1 347 172 Age:overall -0.41 -1.03 0.16 1466.26 1.00 2055 330 155 17 TRUE 0.76
non-small cell lung cancer KRAS_G12D NOTCH1 146 122 Age:overall -0.57 -2.70 0.91 1229.22 1.00 3297 142 118 4 TRUE 0.27
uterine cancer KRAS_G12D NOTCH1 45 82 Age:overall -1.02 -2.94 0.73 30.37 1.09 996 43 80 2 TRUE 0.51
colorectal cancer KRAS_G12D NTRK1 36 12 <40yrs 0.21 -0.91 1.37 1290.22 1.00 175 32 8 4 TRUE 0.14
colorectal cancer KRAS_G12D NTRK1 127 19 50-65yrs -0.25 -1.39 0.69 1564.59 1.00 823 125 17 2 TRUE 0.20
colorectal cancer KRAS_G12D NTRK1 84 26 >65yrs -0.50 -1.91 0.51 1468.70 1.00 542 83 25 1 TRUE 0.38
non-small cell lung cancer KRAS_G12D NTRK1 41 35 50-65yrs -1.90 -5.32 0.25 1169.94 1.01 1241 41 35 0 TRUE 0.77
non-small cell lung cancer KRAS_G12D NTRK1 100 46 >65yrs -1.68 -4.43 0.22 1136.87 1.00 1983 99 45 1 TRUE 0.81
colorectal cancer KRAS_G12D NTRK1 247 57 Age:overall -0.18 -1.39 0.82 1205.90 1.00 1540 240 50 7 TRUE 0.13
non-small cell lung cancer KRAS_G12D NTRK1 141 81 Age:overall -1.76 -4.79 0.37 1282.97 1.00 3224 140 80 1 TRUE 0.76
non-small cell lung cancer KRAS_G12D INPP4A 41 21 50-65yrs -4.78 -11.98 -0.39 527.88 1.01 1247 41 21 0 FALSE 0.91
non-small cell lung cancer KRAS_G12D INPP4A 100 29 >65yrs -4.77 -11.57 -0.49 494.65 1.01 1992 100 29 0 FALSE 0.94
non-small cell lung cancer KRAS_G12D INPP4A 141 50 Age:overall -4.71 -11.37 -0.42 487.81 1.01 3239 141 50 0 FALSE 0.94
colorectal cancer KRAS_G12D CASP8 54 11 40-50yrs -0.63 -2.18 0.43 1598.07 1.00 372 54 11 0 FALSE 0.47
colorectal cancer KRAS_G12D CASP8 122 30 50-65yrs -0.40 -1.46 0.46 1530.92 1.00 795 119 27 3 FALSE 0.38
colorectal cancer KRAS_G12D CASP8 82 46 >65yrs -0.20 -1.07 0.58 1522.12 1.00 518 76 40 6 FALSE 0.20
colorectal cancer KRAS_G12D CASP8 258 87 Age:overall -0.41 -1.52 0.52 1571.94 1.00 1685 249 78 9 FALSE 0.36
colorectal cancer KRAS_G12D SETD2 35 20 <40yrs -0.98 -2.00 -0.13 1280.10 1.00 168 34 19 1 FALSE 1.47
colorectal cancer KRAS_G12D SETD2 56 15 40-50yrs -0.98 -1.92 -0.15 1358.97 1.00 383 55 14 1 FALSE 1.50
colorectal cancer KRAS_G12D SETD2 128 49 50-65yrs -0.97 -1.87 -0.20 1270.68 1.00 803 125 46 3 FALSE 1.61
colorectal cancer KRAS_G12D SETD2 85 29 >65yrs -0.96 -1.90 -0.13 1178.92 1.00 541 83 27 2 FALSE 1.47
non-small cell lung cancer KRAS_G12D SETD2 42 82 50-65yrs -0.03 -1.00 0.80 1335.08 1.00 1206 39 79 3 FALSE 0.03
non-small cell lung cancer KRAS_G12D SETD2 101 132 >65yrs -0.06 -0.80 0.62 1079.35 1.00 1923 95 126 6 FALSE 0.06
uterine cancer KRAS_G12D SETD2 11 14 40-50yrs 0.21 -1.26 1.55 1391.85 1.00 74 8 11 3 FALSE 0.11
uterine cancer KRAS_G12D SETD2 25 39 50-65yrs -0.49 -2.14 0.76 1451.96 1.00 459 24 38 1 FALSE 0.28
uterine cancer KRAS_G12D SETD2 18 31 >65yrs -0.71 -2.96 0.71 1538.44 1.00 431 18 31 0 FALSE 0.34
colorectal cancer KRAS_G12D SETD2 304 113 Age:overall -0.97 -1.88 -0.19 1216.26 1.00 1895 297 106 7 FALSE 1.63
non-small cell lung cancer KRAS_G12D SETD2 143 214 Age:overall -0.02 -0.93 0.91 1369.16 1.00 3129 134 205 9 FALSE 0.02
uterine cancer KRAS_G12D SETD2 54 84 Age:overall -0.32 -1.97 0.97 1436.78 1.00 964 50 80 4 FALSE 0.17
colorectal cancer KRAS_G12D PBRM1 57 21 40-50yrs 0.24 -0.50 0.96 1266.08 1.00 380 52 16 5 TRUE 0.29
colorectal cancer KRAS_G12D PBRM1 129 32 50-65yrs 0.22 -0.48 0.90 1496.94 1.00 819 122 25 7 TRUE 0.28
colorectal cancer KRAS_G12D PBRM1 84 31 >65yrs 0.03 -1.04 0.74 1041.37 1.00 537 83 30 1 TRUE 0.02
non-small cell lung cancer KRAS_G12D PBRM1 41 37 50-65yrs 0.79 -0.61 2.03 1369.90 1.00 1247 37 33 4 TRUE 0.61
non-small cell lung cancer KRAS_G12D PBRM1 100 71 >65yrs -0.64 -2.55 0.65 1320.32 1.00 1966 99 70 1 TRUE 0.35
colorectal cancer KRAS_G12D PBRM1 270 84 Age:overall 0.16 -0.58 0.79 1438.25 1.00 1736 257 71 13 TRUE 0.19
non-small cell lung cancer KRAS_G12D PBRM1 141 108 Age:overall 0.05 -2.03 1.91 1558.42 1.00 3213 136 103 5 TRUE 0.02
colorectal cancer KRAS_G12D EPHA3 35 14 <40yrs -0.85 -1.79 0.00 1313.93 1.00 171 35 14 0 FALSE 1.17
colorectal cancer KRAS_G12D EPHA3 56 15 40-50yrs -0.81 -1.79 0.04 1268.67 1.00 383 55 14 1 FALSE 1.13
colorectal cancer KRAS_G12D EPHA3 127 39 50-65yrs -0.80 -1.67 0.00 1250.76 1.00 805 124 36 3 FALSE 1.24
colorectal cancer KRAS_G12D EPHA3 84 45 >65yrs -0.75 -1.61 0.02 1254.33 1.00 529 80 41 4 FALSE 1.16
non-small cell lung cancer KRAS_G12D EPHA3 8 11 40-50yrs -0.52 -1.67 0.61 1475.31 1.00 175 7 10 1 FALSE 0.45
non-small cell lung cancer KRAS_G12D EPHA3 41 103 50-65yrs -0.58 -1.63 0.31 1407.14 1.00 1185 39 101 2 FALSE 0.64
non-small cell lung cancer KRAS_G12D EPHA3 100 126 >65yrs -0.63 -1.64 0.23 1493.04 1.00 1912 97 123 3 FALSE 0.75
uterine cancer KRAS_G12D EPHA3 25 41 50-65yrs -0.09 -1.41 1.11 222.26 1.02 466 23 39 2 FALSE 0.05
uterine cancer KRAS_G12D EPHA3 18 21 >65yrs -0.09 -1.69 1.31 261.58 1.01 437 17 20 1 FALSE 0.04
colorectal cancer KRAS_G12D EPHA3 302 113 Age:overall -0.80 -1.65 -0.04 1239.76 1.00 1888 294 105 8 FALSE 1.29
non-small cell lung cancer KRAS_G12D EPHA3 149 240 Age:overall -0.57 -1.59 0.30 1415.35 1.00 3272 143 234 6 FALSE 0.63
uterine cancer KRAS_G12D EPHA3 43 62 Age:overall -0.08 -1.70 1.44 336.39 1.02 903 40 59 3 FALSE 0.04
colorectal cancer KRAS_G12D KIT 63 13 40-50yrs -0.68 -1.72 0.27 612.82 1.00 412 61 11 2 TRUE 0.70
colorectal cancer KRAS_G12D KIT 147 20 50-65yrs -0.72 -1.86 0.19 528.23 1.00 910 146 19 1 TRUE 0.76
colorectal cancer KRAS_G12D KIT 95 17 >65yrs -0.71 -1.90 0.21 575.25 1.00 611 94 16 1 TRUE 0.73
non-small cell lung cancer KRAS_G12D KIT 42 25 50-65yrs -4.89 -11.70 -0.79 892.22 1.00 1306 42 25 0 TRUE 1.06
non-small cell lung cancer KRAS_G12D KIT 104 52 >65yrs -4.94 -11.95 -0.93 789.40 1.01 2030 104 52 0 TRUE 1.09
colorectal cancer KRAS_G12D KIT 305 50 Age:overall -0.70 -1.83 0.23 555.53 1.00 1933 301 46 4 TRUE 0.74
non-small cell lung cancer KRAS_G12D KIT 146 77 Age:overall -4.85 -11.62 -0.87 911.78 1.00 3336 146 77 0 TRUE 1.07
colorectal cancer KRAS_G12D KDR 38 11 <40yrs -0.77 -1.97 0.03 112.32 1.03 190 38 11 0 TRUE 1.00
colorectal cancer KRAS_G12D KDR 147 29 50-65yrs -0.73 -1.84 0.06 371.93 1.02 903 144 26 3 TRUE 1.04
colorectal cancer KRAS_G12D KDR 96 26 >65yrs -0.75 -1.92 0.07 447.16 1.02 607 94 24 2 TRUE 1.06
non-small cell lung cancer KRAS_G12D KDR 42 58 50-65yrs -0.42 -1.77 0.71 1344.01 1.00 1279 41 57 1 TRUE 0.31
non-small cell lung cancer KRAS_G12D KDR 105 88 >65yrs -0.30 -1.35 0.63 1031.34 1.00 1996 101 84 4 TRUE 0.26
colorectal cancer KRAS_G12D KDR 281 66 Age:overall -0.75 -1.88 -0.03 374.05 1.02 1700 276 61 5 TRUE 1.10
non-small cell lung cancer KRAS_G12D KDR 147 146 Age:overall -0.36 -1.64 0.73 1324.06 1.00 3275 142 141 5 TRUE 0.24
colorectal cancer KRAS_G12D RICTOR 56 13 40-50yrs -1.28 -2.69 -0.04 208.93 1.01 385 56 13 0 FALSE 1.19
colorectal cancer KRAS_G12D RICTOR 127 24 50-65yrs -1.26 -2.61 -0.11 200.29 1.01 819 126 23 1 FALSE 1.23
colorectal cancer KRAS_G12D RICTOR 85 25 >65yrs -1.22 -2.49 -0.01 207.16 1.01 545 83 23 2 FALSE 1.19
non-small cell lung cancer KRAS_G12D RICTOR 41 24 50-65yrs -1.60 -4.63 0.49 873.20 1.00 1250 41 24 0 FALSE 0.57
non-small cell lung cancer KRAS_G12D RICTOR 100 37 >65yrs -1.39 -4.00 0.38 514.09 1.00 1994 99 36 1 FALSE 0.62
uterine cancer KRAS_G12D RICTOR 25 22 50-65yrs -0.08 -1.92 1.45 216.78 1.01 472 23 20 2 FALSE 0.03
uterine cancer KRAS_G12D RICTOR 18 20 >65yrs -0.48 -3.38 1.19 443.63 1.00 439 18 20 0 FALSE 0.16
colorectal cancer KRAS_G12D RICTOR 268 62 Age:overall -1.25 -2.58 -0.08 199.87 1.01 1749 265 59 3 FALSE 1.23
non-small cell lung cancer KRAS_G12D RICTOR 141 61 Age:overall -1.49 -4.30 0.56 711.07 1.00 3244 140 60 1 FALSE 0.57
uterine cancer KRAS_G12D RICTOR 43 42 Age:overall -0.29 -2.41 1.34 332.72 1.01 911 41 40 2 FALSE 0.11
colorectal cancer KRAS_G12D RAD50 56 13 40-50yrs -0.24 -1.16 0.61 758.57 1.00 385 54 11 2 FALSE 0.22
colorectal cancer KRAS_G12D RAD50 127 22 50-65yrs -0.30 -1.19 0.50 759.76 1.00 821 126 21 1 FALSE 0.30
colorectal cancer KRAS_G12D RAD50 84 20 >65yrs -0.23 -1.14 0.64 812.62 1.00 551 81 17 3 FALSE 0.22
colorectal cancer KRAS_G12D RAD50 267 55 Age:overall -0.26 -1.15 0.55 783.84 1.00 1757 261 49 6 FALSE 0.26
colorectal cancer KRAS_G12D CSF1R 63 15 40-50yrs -1.16 -2.76 0.03 94.14 1.03 411 62 14 1 TRUE 0.97
colorectal cancer KRAS_G12D CSF1R 147 21 50-65yrs -1.14 -2.76 0.01 92.95 1.03 911 145 19 2 TRUE 0.96
colorectal cancer KRAS_G12D CSF1R 95 15 >65yrs -1.20 -2.81 -0.04 102.43 1.02 612 95 15 0 TRUE 1.02
non-small cell lung cancer KRAS_G12D CSF1R 42 22 50-65yrs -1.24 -4.20 1.04 1426.39 1.00 1312 41 21 1 TRUE 0.46
non-small cell lung cancer KRAS_G12D CSF1R 104 45 >65yrs -1.95 -5.50 0.18 1097.62 1.00 2035 104 45 0 TRUE 0.69
colorectal cancer KRAS_G12D CSF1R 305 51 Age:overall -1.16 -2.77 -0.04 92.00 1.03 1934 302 48 3 TRUE 1.02
non-small cell lung cancer KRAS_G12D CSF1R 146 67 Age:overall -1.54 -4.52 0.92 1560.15 1.00 3347 145 66 1 TRUE 0.58
non-small cell lung cancer KRAS_G12D PARK2 41 27 50-65yrs -0.45 -2.48 1.17 1351.59 1.00 1248 40 26 1 FALSE 0.21
non-small cell lung cancer KRAS_G12D PARK2 100 36 >65yrs -0.56 -2.51 0.84 1286.71 1.00 1993 99 35 1 FALSE 0.30
non-small cell lung cancer KRAS_G12D PARK2 141 63 Age:overall -0.52 -2.60 1.03 1377.44 1.00 3241 139 61 2 FALSE 0.24
non-small cell lung cancer KRAS_G12D NTRK2 41 24 50-65yrs -1.23 -3.86 0.84 686.82 1.01 1252 40 23 1 FALSE 0.48
non-small cell lung cancer KRAS_G12D NTRK2 100 39 >65yrs -1.74 -5.11 0.34 918.99 1.00 1993 100 39 0 FALSE 0.68
non-small cell lung cancer KRAS_G12D NTRK2 141 63 Age:overall -1.48 -4.41 0.78 914.44 1.00 3245 140 62 1 FALSE 0.58
colorectal cancer KRAS_G12D PTCH1 35 16 <40yrs -0.61 -1.34 0.13 1384.47 1.00 174 32 13 3 TRUE 0.96
colorectal cancer KRAS_G12D PTCH1 56 21 40-50yrs -0.71 -1.57 0.00 1109.20 1.00 377 55 20 1 TRUE 1.19
colorectal cancer KRAS_G12D PTCH1 127 53 50-65yrs -0.68 -1.42 -0.02 1184.60 1.00 808 123 49 4 TRUE 1.30
colorectal cancer KRAS_G12D PTCH1 84 55 >65yrs -0.70 -1.44 -0.08 1049.14 1.00 522 81 52 3 TRUE 1.34
non-small cell lung cancer KRAS_G12D PTCH1 41 21 50-65yrs -0.68 -3.36 1.01 1153.33 1.00 1253 41 21 0 TRUE 0.26
non-small cell lung cancer KRAS_G12D PTCH1 100 35 >65yrs -0.32 -2.02 0.99 1147.71 1.00 1995 98 33 2 TRUE 0.17
uterine cancer KRAS_G12D PTCH1 25 32 50-65yrs -0.48 -2.34 0.95 971.63 1.00 462 23 30 2 TRUE 0.25
uterine cancer KRAS_G12D PTCH1 18 31 >65yrs -0.94 -3.68 0.74 837.35 1.00 434 18 31 0 TRUE 0.35
colorectal cancer KRAS_G12D PTCH1 302 145 Age:overall -0.67 -1.36 -0.07 1213.11 1.00 1881 291 134 11 TRUE 1.35
non-small cell lung cancer KRAS_G12D PTCH1 141 56 Age:overall -0.51 -2.79 1.09 1096.56 1.00 3248 139 54 2 TRUE 0.23
uterine cancer KRAS_G12D PTCH1 43 63 Age:overall -0.68 -2.70 0.92 947.37 1.00 896 41 61 2 TRUE 0.31
colorectal cancer KRAS_G12D TET1 34 16 <40yrs -0.83 -1.82 0.05 1134.63 1.00 168 33 15 1 FALSE 1.09
colorectal cancer KRAS_G12D TET1 54 23 40-50yrs -0.95 -2.12 -0.07 956.50 1.00 368 54 23 0 FALSE 1.18
colorectal cancer KRAS_G12D TET1 122 27 50-65yrs -0.76 -1.74 0.07 1242.27 1.00 797 119 24 3 FALSE 1.02
colorectal cancer KRAS_G12D TET1 81 37 >65yrs -0.78 -1.73 0.00 1278.94 1.00 524 78 34 3 FALSE 1.08
non-small cell lung cancer KRAS_G12D TET1 41 35 50-65yrs -2.26 -5.36 -0.07 1253.92 1.00 1237 41 35 0 FALSE 1.01
non-small cell lung cancer KRAS_G12D TET1 100 82 >65yrs -2.07 -4.73 -0.30 1110.58 1.00 1948 99 81 1 FALSE 1.15
colorectal cancer KRAS_G12D TET1 291 103 Age:overall -0.83 -1.80 -0.07 1160.47 1.00 1857 284 96 7 FALSE 1.25
non-small cell lung cancer KRAS_G12D TET1 141 117 Age:overall -2.13 -4.95 0.02 1264.34 1.00 3185 140 116 1 FALSE 1.02
colorectal cancer KRAS_G12D FGFR2 63 14 40-50yrs -1.52 -3.46 -0.10 439.51 1.01 409 63 14 0 TRUE 1.14
colorectal cancer KRAS_G12D FGFR2 147 15 50-65yrs -1.54 -3.49 -0.13 434.97 1.01 912 147 15 0 TRUE 1.14
colorectal cancer KRAS_G12D FGFR2 95 17 >65yrs -1.38 -3.22 -0.04 530.84 1.00 612 93 15 2 TRUE 1.04
uterine cancer KRAS_G12D FGFR2 26 43 50-65yrs -1.00 -2.75 0.42 1200.02 1.00 514 25 42 1 TRUE 0.63
uterine cancer KRAS_G12D FGFR2 19 56 >65yrs -1.01 -2.91 0.43 736.07 1.00 451 18 55 1 TRUE 0.64
colorectal cancer KRAS_G12D FGFR2 305 46 Age:overall -1.48 -3.30 -0.13 429.83 1.01 1933 303 44 2 TRUE 1.15
uterine cancer KRAS_G12D FGFR2 45 99 Age:overall -1.02 -3.03 0.55 802.14 1.00 965 43 97 2 TRUE 0.58
colorectal cancer KRAS_G12D TBX3 56 13 40-50yrs -0.11 -1.08 0.51 149.08 1.02 385 55 12 1 FALSE 0.11
colorectal cancer KRAS_G12D TBX3 127 30 50-65yrs 0.01 -0.79 0.70 700.26 1.01 820 120 23 7 FALSE 0.01
colorectal cancer KRAS_G12D TBX3 84 30 >65yrs -0.16 -1.21 0.44 66.07 1.04 542 83 29 1 FALSE 0.16
non-small cell lung cancer KRAS_G12D TBX3 41 58 50-65yrs -2.17 -5.36 -0.40 54.26 1.06 1223 41 58 0 FALSE 0.99
non-small cell lung cancer KRAS_G12D TBX3 100 74 >65yrs -1.99 -4.61 -0.37 110.63 1.04 1957 99 73 1 FALSE 1.14
uterine cancer KRAS_G12D TBX3 25 27 50-65yrs -0.17 -1.94 1.21 940.60 1.00 464 23 25 2 FALSE 0.08
uterine cancer KRAS_G12D TBX3 18 18 >65yrs -0.63 -3.81 1.05 1215.52 1.00 441 18 18 0 FALSE 0.21
colorectal cancer KRAS_G12D TBX3 267 73 Age:overall -0.09 -0.94 0.54 153.14 1.02 1747 258 64 9 FALSE 0.10
non-small cell lung cancer KRAS_G12D TBX3 141 132 Age:overall -2.05 -4.98 -0.22 89.72 1.05 3180 140 131 1 FALSE 1.05
uterine cancer KRAS_G12D TBX3 43 45 Age:overall -0.40 -2.75 1.32 1141.40 1.00 905 41 43 2 FALSE 0.16
colorectal cancer KRAS_G12D HNF1A 147 25 50-65yrs -0.28 -1.38 0.64 718.77 1.00 907 144 22 3 TRUE 0.22
colorectal cancer KRAS_G12D HNF1A 95 19 >65yrs -0.28 -1.47 0.72 814.29 1.00 609 93 17 2 TRUE 0.21
colorectal cancer KRAS_G12D HNF1A 242 44 Age:overall -0.27 -1.47 0.74 753.67 1.00 1516 237 39 5 TRUE 0.20
colorectal cancer KRAS_G12D DICER1 35 11 <40yrs -0.61 -1.56 0.23 712.27 1.00 177 33 9 2 TRUE 0.72
colorectal cancer KRAS_G12D DICER1 56 19 40-50yrs -0.63 -1.55 0.21 584.38 1.00 381 54 17 2 TRUE 0.77
colorectal cancer KRAS_G12D DICER1 127 23 50-65yrs -0.70 -1.59 0.08 516.23 1.00 822 126 22 1 TRUE 0.90
colorectal cancer KRAS_G12D DICER1 84 23 >65yrs -0.69 -1.59 0.15 636.19 1.00 546 83 22 1 TRUE 0.85
non-small cell lung cancer KRAS_G12D DICER1 41 26 50-65yrs -1.94 -5.46 0.24 1357.74 1.00 1248 41 26 0 TRUE 0.69
non-small cell lung cancer KRAS_G12D DICER1 100 59 >65yrs -1.68 -4.38 0.11 1243.08 1.00 1975 99 58 1 TRUE 0.89
uterine cancer KRAS_G12D DICER1 25 36 50-65yrs -1.00 -3.52 0.51 748.82 1.00 463 25 36 0 TRUE 0.38
uterine cancer KRAS_G12D DICER1 19 33 >65yrs -0.49 -2.54 1.03 880.66 1.00 434 17 31 2 TRUE 0.24
colorectal cancer KRAS_G12D DICER1 302 76 Age:overall -0.66 -1.55 0.13 612.31 1.00 1926 296 70 6 TRUE 0.85
non-small cell lung cancer KRAS_G12D DICER1 141 85 Age:overall -1.78 -4.77 0.30 1408.57 1.00 3223 140 84 1 TRUE 0.77
uterine cancer KRAS_G12D DICER1 44 69 Age:overall -0.72 -3.10 0.84 707.39 1.00 897 42 67 2 TRUE 0.33
colorectal cancer KRAS_G12D SMAD3 59 33 40-50yrs 0.18 -0.44 0.77 6.87 1.35 371 54 28 5 TRUE 0.18
colorectal cancer KRAS_G12D SMAD3 130 44 50-65yrs 0.18 -0.38 0.73 5.72 1.41 807 122 36 8 TRUE 0.19
colorectal cancer KRAS_G12D SMAD3 84 23 >65yrs 0.13 -0.60 0.73 6.12 1.31 546 81 20 3 TRUE 0.12
colorectal cancer KRAS_G12D SMAD3 273 100 Age:overall 0.16 -0.45 0.76 6.37 1.36 1724 257 84 16 TRUE 0.17
colorectal cancer KRAS_G12D NTRK3 35 11 <40yrs -0.68 -1.77 0.13 237.42 1.01 174 33 9 2 FALSE 0.75
colorectal cancer KRAS_G12D NTRK3 56 16 40-50yrs -0.77 -1.94 0.08 204.33 1.02 383 56 16 0 FALSE 0.84
colorectal cancer KRAS_G12D NTRK3 127 21 50-65yrs -0.72 -1.80 0.08 216.95 1.02 822 125 19 2 FALSE 0.84
colorectal cancer KRAS_G12D NTRK3 84 22 >65yrs -0.74 -1.83 0.06 192.45 1.02 546 83 21 1 FALSE 0.86
non-small cell lung cancer KRAS_G12D NTRK3 41 64 50-65yrs -1.51 -3.88 -0.14 254.17 1.01 1216 41 64 0 FALSE 0.82
non-small cell lung cancer KRAS_G12D NTRK3 100 134 >65yrs -1.11 -2.67 -0.10 462.61 1.02 1915 97 131 3 FALSE 1.10
colorectal cancer KRAS_G12D NTRK3 302 70 Age:overall -0.72 -1.79 0.05 185.58 1.02 1925 297 65 5 FALSE 0.86
non-small cell lung cancer KRAS_G12D NTRK3 141 198 Age:overall -1.26 -3.07 0.07 315.78 1.02 3131 138 195 3 FALSE 0.91
colorectal cancer KRAS_G12D AXIN1 128 22 50-65yrs -0.48 -1.69 0.56 1315.98 1.00 822 126 20 2 FALSE 0.39
colorectal cancer KRAS_G12D AXIN1 84 37 >65yrs -0.32 -1.38 0.55 1433.70 1.00 537 80 33 4 FALSE 0.29
colorectal cancer KRAS_G12D AXIN1 212 59 Age:overall -0.38 -1.71 0.93 1354.79 1.00 1359 206 53 6 FALSE 0.24
colorectal cancer KRAS_G12D GRIN2A 35 15 <40yrs -0.52 -1.17 0.11 759.41 1.00 170 34 14 1 FALSE 0.97
colorectal cancer KRAS_G12D GRIN2A 56 29 40-50yrs -0.49 -1.14 0.13 657.56 1.00 376 52 25 4 FALSE 0.93
colorectal cancer KRAS_G12D GRIN2A 127 50 50-65yrs -0.51 -1.14 0.09 695.17 1.00 796 122 45 5 FALSE 1.00
colorectal cancer KRAS_G12D GRIN2A 84 42 >65yrs -0.53 -1.22 0.09 971.59 1.00 530 82 40 2 FALSE 1.03
non-small cell lung cancer KRAS_G12D GRIN2A 8 11 40-50yrs -0.16 -1.34 0.75 665.40 1.00 173 8 11 0 FALSE 0.11
non-small cell lung cancer KRAS_G12D GRIN2A 41 70 50-65yrs -0.19 -1.21 0.68 718.78 1.00 1210 40 69 1 FALSE 0.15
non-small cell lung cancer KRAS_G12D GRIN2A 101 110 >65yrs 0.00 -0.87 0.75 299.59 1.01 1930 94 103 7 FALSE 0.00
uterine cancer KRAS_G12D GRIN2A 9 12 40-50yrs -2.02 -5.15 0.11 1076.44 1.00 76 9 12 0 FALSE 0.84
uterine cancer KRAS_G12D GRIN2A 25 35 50-65yrs -2.12 -5.21 -0.07 1106.47 1.00 459 25 35 0 FALSE 0.94
uterine cancer KRAS_G12D GRIN2A 18 26 >65yrs -1.70 -4.66 0.33 1155.14 1.00 438 17 25 1 FALSE 0.73
colorectal cancer KRAS_G12D GRIN2A 302 136 Age:overall -0.52 -1.14 0.07 872.17 1.00 1872 290 124 12 FALSE 1.03
non-small cell lung cancer KRAS_G12D GRIN2A 150 191 Age:overall -0.11 -1.06 0.75 443.81 1.00 3313 142 183 8 FALSE 0.09
uterine cancer KRAS_G12D GRIN2A 52 73 Age:overall -1.93 -4.67 0.10 1123.70 1.00 973 51 72 1 FALSE 0.88
colorectal cancer KRAS_G12D PALB2 35 13 <40yrs -1.52 -3.54 0.03 973.58 1.00 172 34 12 1 TRUE 1.05
colorectal cancer KRAS_G12D PALB2 127 18 50-65yrs -1.57 -3.63 -0.12 820.43 1.00 824 126 17 1 TRUE 1.12
colorectal cancer KRAS_G12D PALB2 84 20 >65yrs -1.75 -3.91 -0.31 705.67 1.00 547 84 20 0 TRUE 1.21
non-small cell lung cancer KRAS_G12D PALB2 41 30 50-65yrs -0.94 -4.40 0.83 1224.12 1.00 1247 41 30 0 TRUE 0.31
non-small cell lung cancer KRAS_G12D PALB2 100 29 >65yrs -0.25 -2.14 1.19 1037.84 1.00 2001 98 27 2 TRUE 0.12
colorectal cancer KRAS_G12D PALB2 246 51 Age:overall -1.59 -3.54 -0.07 787.92 1.00 1543 244 49 2 TRUE 1.13
non-small cell lung cancer KRAS_G12D PALB2 141 59 Age:overall -0.60 -3.13 1.13 1207.76 1.00 3248 139 57 2 TRUE 0.24
colorectal cancer KRAS_G12D CTCF 57 20 40-50yrs 0.53 -0.21 1.51 1259.82 1.00 384 50 13 7 FALSE 0.66
colorectal cancer KRAS_G12D CTCF 127 30 50-65yrs 0.28 -0.44 0.91 1053.51 1.00 818 122 25 5 FALSE 0.37
colorectal cancer KRAS_G12D CTCF 84 32 >65yrs 0.11 -0.90 0.81 985.04 1.00 540 82 30 2 FALSE 0.10
uterine cancer KRAS_G12D CTCF 9 16 40-50yrs 0.26 -0.72 1.22 1368.86 1.00 68 7 14 2 FALSE 0.22
uterine cancer KRAS_G12D CTCF 26 85 50-65yrs 0.35 -0.46 1.10 1463.89 1.00 421 19 78 7 FALSE 0.41
uterine cancer KRAS_G12D CTCF 18 65 >65yrs -0.01 -1.23 0.91 920.49 1.01 398 17 64 1 FALSE 0.00
colorectal cancer KRAS_G12D CTCF 268 82 Age:overall 0.31 -0.37 1.00 1185.50 1.00 1742 254 68 14 FALSE 0.41
uterine cancer KRAS_G12D CTCF 53 166 Age:overall 0.20 -0.82 1.05 1455.00 1.00 887 43 156 10 FALSE 0.18
colorectal cancer KRAS_G12D CDH1 148 22 50-65yrs -0.18 -1.34 0.80 1225.77 1.00 910 145 19 3 TRUE 0.14
colorectal cancer KRAS_G12D CDH1 95 18 >65yrs -0.21 -1.51 0.88 1299.15 1.00 614 93 16 2 TRUE 0.15
colorectal cancer KRAS_G12D CDH1 243 40 Age:overall -0.20 -1.49 0.90 1191.35 1.00 1524 238 35 5 TRUE 0.13
colorectal cancer KRAS_G12D CDK12 56 13 40-50yrs -0.87 -1.96 0.04 648.12 1.00 384 54 11 2 FALSE 1.01
colorectal cancer KRAS_G12D CDK12 127 39 50-65yrs -0.88 -1.96 0.03 652.80 1.00 809 124 36 3 FALSE 1.08
colorectal cancer KRAS_G12D CDK12 84 28 >65yrs -0.97 -2.13 -0.03 735.96 1.00 544 84 28 0 FALSE 1.05
non-small cell lung cancer KRAS_G12D CDK12 41 15 50-65yrs -0.89 -3.85 1.48 1063.43 1.00 1260 40 14 1 FALSE 0.30
non-small cell lung cancer KRAS_G12D CDK12 100 42 >65yrs -1.82 -5.23 0.25 757.15 1.00 1988 100 42 0 FALSE 0.62
colorectal cancer KRAS_G12D CDK12 267 80 Age:overall -0.91 -2.02 0.00 673.65 1.00 1737 262 75 5 FALSE 1.12
non-small cell lung cancer KRAS_G12D CDK12 141 57 Age:overall -1.26 -4.12 1.36 1012.11 1.00 3248 140 56 1 FALSE 0.45
cancer of unknown primary KRAS_G12D STK11 21 23 50-65yrs -5.30 -10.95 -0.98 1012.96 1.01 272 21 23 0 TRUE 1.43
cancer of unknown primary KRAS_G12D STK11 26 24 >65yrs -5.28 -10.90 -1.01 786.46 1.01 316 26 24 0 TRUE 1.44
non-small cell lung cancer KRAS_G12D STK11 8 19 40-50yrs 0.60 -0.29 1.67 1557.69 1.00 176 6 17 2 TRUE 0.66
non-small cell lung cancer KRAS_G12D STK11 42 196 50-65yrs 0.72 0.07 1.40 1418.23 1.00 1155 29 183 13 TRUE 1.47
non-small cell lung cancer KRAS_G12D STK11 105 326 >65yrs 0.22 -0.33 0.67 1649.42 1.00 1780 89 310 16 TRUE 0.40
cancer of unknown primary KRAS_G12D STK11 47 47 Age:overall -5.24 -10.82 -0.91 831.81 1.01 588 47 47 0 TRUE 1.43
non-small cell lung cancer KRAS_G12D STK11 155 541 Age:overall 0.52 -0.18 1.26 1492.56 1.00 3111 124 510 31 TRUE 0.83
colorectal cancer KRAS_G12D DNMT1 34 13 <40yrs -0.52 -1.41 0.20 1497.86 1.00 165 33 12 1 FALSE 0.67
colorectal cancer KRAS_G12D DNMT1 54 18 40-50yrs -0.55 -1.42 0.20 1310.69 1.00 368 54 18 0 FALSE 0.71
colorectal cancer KRAS_G12D DNMT1 124 36 50-65yrs -0.46 -1.28 0.24 1610.34 1.00 790 118 30 6 FALSE 0.61
colorectal cancer KRAS_G12D DNMT1 81 23 >65yrs -0.54 -1.40 0.21 1428.04 1.00 531 80 22 1 FALSE 0.72
colorectal cancer KRAS_G12D DNMT1 293 90 Age:overall -0.52 -1.35 0.20 1405.01 1.00 1854 285 82 8 FALSE 0.73
colorectal cancer KRAS_G12D BRD4 129 40 50-65yrs -0.32 -1.16 0.55 293.02 1.00 809 123 34 6 FALSE 0.31
colorectal cancer KRAS_G12D BRD4 84 33 >65yrs -0.73 -2.33 0.31 755.32 1.00 535 83 32 1 FALSE 0.57
non-small cell lung cancer KRAS_G12D BRD4 41 15 50-65yrs -4.68 -12.10 -0.31 682.65 1.01 1259 41 15 0 FALSE 0.89
non-small cell lung cancer KRAS_G12D BRD4 100 37 >65yrs -4.71 -12.24 -0.50 645.66 1.01 1993 100 37 0 FALSE 0.90
uterine cancer KRAS_G12D BRD4 25 32 50-65yrs -0.64 -2.50 0.84 179.30 1.01 464 24 31 1 FALSE 0.33
uterine cancer KRAS_G12D BRD4 18 31 >65yrs -0.62 -2.46 0.92 181.84 1.01 429 17 30 1 FALSE 0.31
colorectal cancer KRAS_G12D BRD4 213 73 Age:overall -0.49 -1.79 0.56 860.71 1.00 1344 206 66 7 FALSE 0.35
non-small cell lung cancer KRAS_G12D BRD4 141 52 Age:overall -4.60 -11.86 -0.30 709.45 1.01 3252 141 52 0 FALSE 0.89
uterine cancer KRAS_G12D BRD4 43 63 Age:overall -0.63 -2.44 1.04 213.75 1.01 893 41 61 2 FALSE 0.30
colorectal cancer KRAS_G12D ASXL1 56 21 40-50yrs -0.98 -2.02 -0.09 637.45 1.00 376 55 20 1 TRUE 1.37
colorectal cancer KRAS_G12D ASXL1 127 40 50-65yrs -0.95 -1.93 -0.09 575.53 1.00 805 124 37 3 TRUE 1.40
colorectal cancer KRAS_G12D ASXL1 84 40 >65yrs -0.98 -1.95 -0.15 616.50 1.00 533 82 38 2 TRUE 1.48
non-small cell lung cancer KRAS_G12D ASXL1 41 29 50-65yrs -0.68 -2.57 0.77 557.84 1.01 1246 40 28 1 TRUE 0.38
non-small cell lung cancer KRAS_G12D ASXL1 100 53 >65yrs -0.83 -2.73 0.48 393.87 1.01 1990 99 52 1 TRUE 0.52
uterine cancer KRAS_G12D ASXL1 25 19 50-65yrs -1.21 -3.83 0.96 144.82 1.04 473 24 18 1 TRUE 0.46
uterine cancer KRAS_G12D ASXL1 18 29 >65yrs -1.63 -4.76 0.59 342.93 1.02 432 18 29 0 TRUE 0.51
colorectal cancer KRAS_G12D ASXL1 267 101 Age:overall -0.96 -1.95 -0.10 598.16 1.00 1714 261 95 6 TRUE 1.46
non-small cell lung cancer KRAS_G12D ASXL1 141 82 Age:overall -0.74 -2.67 0.69 516.31 1.01 3236 139 80 2 TRUE 0.42
uterine cancer KRAS_G12D ASXL1 43 48 Age:overall -1.40 -4.05 0.82 179.30 1.03 905 42 47 1 TRUE 0.52
colorectal cancer KRAS_G12D EP300 35 15 <40yrs -0.68 -1.60 0.24 1412.07 1.00 172 33 13 2 TRUE 0.81
colorectal cancer KRAS_G12D EP300 56 16 40-50yrs -0.80 -1.91 0.15 1447.65 1.00 381 55 15 1 TRUE 0.93
colorectal cancer KRAS_G12D EP300 128 38 50-65yrs -0.56 -1.44 0.29 1418.04 1.00 814 123 33 5 TRUE 0.72
colorectal cancer KRAS_G12D EP300 84 56 >65yrs -1.04 -2.11 -0.22 1129.57 1.00 522 83 55 1 TRUE 1.49
non-small cell lung cancer KRAS_G12D EP300 41 30 50-65yrs -1.38 -4.45 0.41 1208.99 1.01 1246 41 30 0 TRUE 0.54
non-small cell lung cancer KRAS_G12D EP300 100 74 >65yrs -0.98 -2.77 0.33 1317.20 1.00 1965 98 72 2 TRUE 0.67
uterine cancer KRAS_G12D EP300 10 15 40-50yrs -0.16 -1.61 1.13 1534.67 1.00 75 8 13 2 TRUE 0.09
uterine cancer KRAS_G12D EP300 25 37 50-65yrs -0.28 -1.70 0.92 1532.27 1.00 459 23 35 2 TRUE 0.17
uterine cancer KRAS_G12D EP300 18 47 >65yrs -0.78 -2.84 0.56 1447.98 1.00 419 18 47 0 TRUE 0.42
colorectal cancer KRAS_G12D EP300 303 125 Age:overall -0.76 -1.60 0.01 1418.14 1.00 1889 294 116 9 TRUE 1.19
non-small cell lung cancer KRAS_G12D EP300 141 104 Age:overall -1.16 -3.44 0.55 1258.40 1.00 3211 139 102 2 TRUE 0.60
uterine cancer KRAS_G12D EP300 53 99 Age:overall -0.42 -2.02 0.78 1509.57 1.00 953 49 95 4 TRUE 0.25
colorectal cancer KRAS_G12D ERBB4 38 17 <40yrs -0.14 -0.72 0.40 471.00 1.00 188 36 15 2 TRUE 0.19
colorectal cancer KRAS_G12D ERBB4 63 20 40-50yrs -0.12 -0.70 0.40 559.89 1.00 409 59 16 4 TRUE 0.18
colorectal cancer KRAS_G12D ERBB4 147 60 50-65yrs -0.14 -0.70 0.36 448.25 1.01 882 140 53 7 TRUE 0.22
colorectal cancer KRAS_G12D ERBB4 95 41 >65yrs -0.15 -0.71 0.37 347.34 1.01 592 91 37 4 TRUE 0.22
non-small cell lung cancer KRAS_G12D ERBB4 42 80 50-65yrs -1.42 -5.77 0.43 1330.09 1.00 1265 42 80 0 TRUE 0.38
non-small cell lung cancer KRAS_G12D ERBB4 104 105 >65yrs 0.30 -0.52 1.02 1476.14 1.00 1996 96 97 8 TRUE 0.33
colorectal cancer KRAS_G12D ERBB4 343 138 Age:overall -0.14 -0.68 0.35 409.36 1.01 2071 326 121 17 TRUE 0.21
non-small cell lung cancer KRAS_G12D ERBB4 146 185 Age:overall -0.51 -3.63 1.19 1395.08 1.00 3261 138 177 8 TRUE 0.18
colorectal cancer KRAS_G12D MDC1 122 30 50-65yrs -0.70 -1.87 0.32 905.95 1.00 794 120 28 2 FALSE 0.69
colorectal cancer KRAS_G12D MDC1 81 19 >65yrs -0.62 -1.82 0.45 931.95 1.00 535 79 17 2 FALSE 0.55
non-small cell lung cancer KRAS_G12D MDC1 41 36 50-65yrs -0.79 -2.81 0.72 1433.60 1.00 1234 40 35 1 FALSE 0.41
non-small cell lung cancer KRAS_G12D MDC1 100 53 >65yrs -0.92 -2.78 0.43 1375.35 1.00 1978 99 52 1 FALSE 0.56
colorectal cancer KRAS_G12D MDC1 203 49 Age:overall -0.66 -1.91 0.45 1033.55 1.00 1329 199 45 4 FALSE 0.56
non-small cell lung cancer KRAS_G12D MDC1 141 89 Age:overall -0.85 -2.85 0.66 1422.16 1.00 3212 139 87 2 FALSE 0.46
colorectal cancer KRAS_G12D RECQL4 34 13 <40yrs 0.38 -0.27 1.06 1258.75 1.00 171 30 9 4 TRUE 0.56
colorectal cancer KRAS_G12D RECQL4 54 13 40-50yrs 0.34 -0.29 1.01 1352.32 1.00 373 51 10 3 TRUE 0.53
colorectal cancer KRAS_G12D RECQL4 122 34 50-65yrs 0.31 -0.34 0.89 1300.74 1.00 793 117 29 5 TRUE 0.47
colorectal cancer KRAS_G12D RECQL4 81 21 >65yrs 0.29 -0.39 0.92 1343.55 1.00 534 79 19 2 TRUE 0.41
non-small cell lung cancer KRAS_G12D RECQL4 41 25 50-65yrs -4.90 -11.37 -0.57 393.71 1.01 1243 41 25 0 TRUE 1.05
non-small cell lung cancer KRAS_G12D RECQL4 100 35 >65yrs -4.91 -11.55 -0.75 398.59 1.00 1989 100 35 0 TRUE 1.04
colorectal cancer KRAS_G12D RECQL4 291 81 Age:overall 0.33 -0.28 0.93 1346.93 1.00 1871 277 67 14 TRUE 0.53
non-small cell lung cancer KRAS_G12D RECQL4 141 60 Age:overall -4.83 -11.33 -0.60 396.81 1.00 3232 141 60 0 TRUE 1.05
colorectal cancer KRAS_G12D MED12 36 13 <40yrs -0.44 -1.34 0.46 989.97 1.01 174 32 9 4 TRUE 0.48
colorectal cancer KRAS_G12D MED12 56 18 40-50yrs -0.62 -1.58 0.16 1251.80 1.00 378 55 17 1 TRUE 0.81
colorectal cancer KRAS_G12D MED12 127 35 50-65yrs -0.60 -1.47 0.17 922.37 1.01 816 124 32 3 TRUE 0.82
colorectal cancer KRAS_G12D MED12 84 42 >65yrs -0.70 -1.63 0.02 1283.06 1.00 529 83 41 1 TRUE 1.02
non-small cell lung cancer KRAS_G12D MED12 41 64 50-65yrs -0.77 -2.21 0.36 1390.33 1.00 1218 40 63 1 TRUE 0.62
non-small cell lung cancer KRAS_G12D MED12 100 104 >65yrs -0.70 -1.86 0.22 1451.34 1.00 1933 97 101 3 TRUE 0.71
uterine cancer KRAS_G12D MED12 25 73 50-65yrs -1.95 -5.24 -0.16 1232.60 1.00 430 25 73 0 TRUE 0.79
uterine cancer KRAS_G12D MED12 18 48 >65yrs -0.92 -2.87 0.74 972.58 1.00 420 16 46 2 TRUE 0.49
colorectal cancer KRAS_G12D MED12 303 108 Age:overall -0.59 -1.42 0.14 1045.02 1.00 1897 294 99 9 TRUE 0.89
non-small cell lung cancer KRAS_G12D MED12 141 168 Age:overall -0.72 -2.12 0.44 1355.63 1.00 3151 137 164 4 TRUE 0.53
uterine cancer KRAS_G12D MED12 43 121 Age:overall -1.40 -3.74 0.51 1367.04 1.00 850 41 119 2 TRUE 0.68
colorectal cancer KRAS_G12D ERCC5 54 13 40-50yrs -0.78 -2.03 0.18 1200.25 1.00 371 54 13 0 TRUE 0.76
colorectal cancer KRAS_G12D ERCC5 122 20 50-65yrs -0.71 -1.86 0.19 850.89 1.00 800 120 18 2 TRUE 0.75
colorectal cancer KRAS_G12D ERCC5 81 22 >65yrs -0.71 -1.87 0.26 1057.99 1.00 534 79 20 2 TRUE 0.72
non-small cell lung cancer KRAS_G12D ERCC5 41 28 50-65yrs -0.57 -2.36 1.02 1243.24 1.00 1242 40 27 1 TRUE 0.29
non-small cell lung cancer KRAS_G12D ERCC5 100 43 >65yrs -0.71 -2.51 0.67 1349.43 1.00 1984 99 42 1 TRUE 0.40
uterine cancer KRAS_G12D ERCC5 10 15 40-50yrs 1.54 0.27 2.84 1488.57 1.00 67 5 10 5 TRUE 1.72
uterine cancer KRAS_G12D ERCC5 24 17 50-65yrs 0.29 -1.63 1.72 1297.24 1.00 453 23 16 1 TRUE 0.13
uterine cancer KRAS_G12D ERCC5 16 17 >65yrs -0.18 -3.15 1.62 1390.71 1.00 421 16 17 0 TRUE 0.05
colorectal cancer KRAS_G12D ERCC5 257 55 Age:overall -0.74 -1.90 0.18 897.25 1.00 1705 253 51 4 TRUE 0.76
non-small cell lung cancer KRAS_G12D ERCC5 141 71 Age:overall -0.62 -2.59 0.93 1199.81 1.00 3226 139 69 2 TRUE 0.30
uterine cancer KRAS_G12D ERCC5 50 49 Age:overall 0.52 -1.54 2.06 1454.35 1.00 941 44 43 6 TRUE 0.24
colorectal cancer KRAS_G12D PIK3CD 55 17 40-50yrs -0.32 -1.43 0.68 1446.37 1.00 369 52 14 3 FALSE 0.25
colorectal cancer KRAS_G12D PIK3CD 122 18 50-65yrs -0.48 -1.64 0.48 1632.51 1.00 801 120 16 2 FALSE 0.43
colorectal cancer KRAS_G12D PIK3CD 81 31 >65yrs -0.69 -1.92 0.25 1344.46 1.00 526 80 30 1 FALSE 0.67
colorectal cancer KRAS_G12D PIK3CD 258 66 Age:overall -0.50 -1.65 0.45 1484.62 1.00 1696 252 60 6 FALSE 0.45
colorectal cancer KRAS_G12D BRCA1 35 19 <40yrs -0.39 -1.48 0.58 1481.67 1.00 173 33 17 2 TRUE 0.35
colorectal cancer KRAS_G12D BRCA1 56 15 40-50yrs -0.49 -1.72 0.45 1406.49 1.00 382 55 14 1 TRUE 0.44
colorectal cancer KRAS_G12D BRCA1 127 19 50-65yrs -0.58 -1.69 0.32 1482.18 1.00 823 126 18 1 TRUE 0.57
colorectal cancer KRAS_G12D BRCA1 84 26 >65yrs -0.23 -1.18 0.69 1638.52 1.00 547 80 22 4 TRUE 0.21
non-small cell lung cancer KRAS_G12D BRCA1 41 32 50-65yrs -0.62 -3.68 0.80 730.90 1.00 1243 41 32 0 TRUE 0.21
non-small cell lung cancer KRAS_G12D BRCA1 100 61 >65yrs -0.08 -1.17 1.01 38.10 1.09 1975 96 57 4 TRUE 0.05
colorectal cancer KRAS_G12D BRCA1 302 79 Age:overall -0.42 -1.36 0.42 1500.76 1.00 1925 294 71 8 TRUE 0.45
non-small cell lung cancer KRAS_G12D BRCA1 141 93 Age:overall -0.31 -2.31 1.17 811.57 1.01 3218 137 89 4 TRUE 0.13
colorectal cancer KRAS_G12D RBM10 127 38 50-65yrs 0.04 -0.82 0.81 1273.16 1.00 811 120 31 7 FALSE 0.03
colorectal cancer KRAS_G12D RBM10 84 22 >65yrs -0.24 -1.69 0.62 1095.61 1.00 548 83 21 1 FALSE 0.16
non-small cell lung cancer KRAS_G12D RBM10 8 11 40-50yrs 0.72 -0.34 1.69 1502.99 1.00 174 7 10 1 FALSE 0.85
non-small cell lung cancer KRAS_G12D RBM10 42 106 50-65yrs 0.77 0.06 1.39 1423.56 1.00 1183 35 99 7 FALSE 1.68
non-small cell lung cancer KRAS_G12D RBM10 103 265 >65yrs 0.72 0.27 1.17 1526.10 1.00 1792 81 243 22 FALSE 2.60
uterine cancer KRAS_G12D RBM10 9 13 40-50yrs 0.19 -1.45 1.61 1477.88 1.00 74 7 11 2 FALSE 0.09
uterine cancer KRAS_G12D RBM10 25 20 50-65yrs -0.19 -2.04 1.25 1513.69 1.00 469 24 19 1 FALSE 0.09
uterine cancer KRAS_G12D RBM10 18 19 >65yrs -0.53 -2.99 1.13 1522.93 1.00 443 18 19 0 FALSE 0.22
colorectal cancer KRAS_G12D RBM10 211 60 Age:overall -0.10 -1.23 0.77 1240.55 1.00 1359 203 52 8 FALSE 0.06
non-small cell lung cancer KRAS_G12D RBM10 153 382 Age:overall 0.72 0.01 1.46 1568.93 1.00 3149 123 352 30 FALSE 1.30
uterine cancer KRAS_G12D RBM10 52 52 Age:overall -0.20 -2.01 1.31 1543.08 1.00 986 49 49 3 FALSE 0.09
colorectal cancer KRAS_G12D TSC1 127 23 50-65yrs -0.18 -1.27 0.74 1188.98 1.00 823 124 20 3 TRUE 0.14
colorectal cancer KRAS_G12D TSC1 84 27 >65yrs -0.19 -1.33 0.72 1361.75 1.00 546 81 24 3 TRUE 0.14
non-small cell lung cancer KRAS_G12D TSC1 41 23 50-65yrs -6.10 -10.94 -0.72 3.38 1.33 1252 41 23 0 TRUE 1.40
non-small cell lung cancer KRAS_G12D TSC1 100 33 >65yrs -6.10 -10.86 -0.82 3.33 1.34 1995 100 33 0 TRUE 1.40
uterine cancer KRAS_G12D TSC1 25 32 50-65yrs 0.56 -0.66 1.59 903.30 1.00 469 22 29 3 TRUE 0.47
uterine cancer KRAS_G12D TSC1 18 19 >65yrs 0.43 -1.10 1.69 1109.56 1.00 439 17 18 1 TRUE 0.27
colorectal cancer KRAS_G12D TSC1 211 50 Age:overall -0.18 -1.37 0.87 1388.26 1.00 1369 205 44 6 TRUE 0.12
non-small cell lung cancer KRAS_G12D TSC1 141 56 Age:overall -6.07 -10.71 -0.72 3.25 1.35 3247 141 56 0 TRUE 1.40
uterine cancer KRAS_G12D TSC1 43 51 Age:overall 0.49 -0.88 1.71 1000.76 1.00 908 39 47 4 TRUE 0.32
colorectal cancer KRAS_G12D FLCN 128 23 50-65yrs -0.43 -1.68 0.57 1402.64 1.00 824 125 20 3 TRUE 0.34
colorectal cancer KRAS_G12D FLCN 84 19 >65yrs -0.56 -1.88 0.45 1261.38 1.00 547 83 18 1 TRUE 0.46
colorectal cancer KRAS_G12D FLCN 212 42 Age:overall -0.50 -1.89 0.60 1427.29 1.00 1371 208 38 4 TRUE 0.35
cancer of unknown primary KRAS_G12D NF1 21 23 50-65yrs -1.73 -4.35 0.27 941.10 1.00 271 20 22 1 TRUE 0.86
cancer of unknown primary KRAS_G12D NF1 26 28 >65yrs -1.95 -4.78 0.06 1094.33 1.00 312 26 28 0 TRUE 0.98
colorectal cancer KRAS_G12D NF1 36 23 <40yrs -0.59 -1.36 0.13 1155.86 1.00 170 32 19 4 TRUE 0.90
colorectal cancer KRAS_G12D NF1 56 21 40-50yrs -0.76 -1.62 -0.07 1040.20 1.00 381 56 21 0 TRUE 1.20
colorectal cancer KRAS_G12D NF1 127 58 50-65yrs -0.66 -1.37 -0.04 999.57 1.00 796 122 53 5 TRUE 1.25
colorectal cancer KRAS_G12D NF1 84 40 >65yrs -0.71 -1.47 -0.03 1043.49 1.00 538 82 38 2 TRUE 1.27
non-small cell lung cancer KRAS_G12D NF1 8 12 40-50yrs -0.75 -1.79 0.21 1361.89 1.00 173 8 12 0 TRUE 0.85
non-small cell lung cancer KRAS_G12D NF1 41 110 50-65yrs -0.66 -1.62 0.23 1172.32 1.00 1183 38 107 3 TRUE 0.83
non-small cell lung cancer KRAS_G12D NF1 100 191 >65yrs -0.76 -1.60 0.00 1205.34 1.00 1868 96 187 4 TRUE 1.13
uterine cancer KRAS_G12D NF1 9 21 40-50yrs -0.59 -2.21 0.77 1467.78 1.00 70 8 20 1 TRUE 0.36
uterine cancer KRAS_G12D NF1 25 62 50-65yrs -0.56 -1.91 0.61 1049.66 1.00 452 23 60 2 TRUE 0.42
uterine cancer KRAS_G12D NF1 18 31 >65yrs -0.53 -2.17 0.83 1568.55 1.00 432 17 30 1 TRUE 0.31
cancer of unknown primary KRAS_G12D NF1 47 51 Age:overall -1.84 -4.38 0.20 1065.77 1.00 583 46 50 1 TRUE 0.93
colorectal cancer KRAS_G12D NF1 303 142 Age:overall -0.68 -1.39 -0.06 1031.66 1.00 1885 292 131 11 TRUE 1.33
non-small cell lung cancer KRAS_G12D NF1 149 313 Age:overall -0.72 -1.65 0.12 980.36 1.00 3224 142 306 7 TRUE 1.00
uterine cancer KRAS_G12D NF1 52 114 Age:overall -0.56 -2.03 0.73 1217.61 1.00 954 48 110 4 TRUE 0.37
colorectal cancer KRAS_G12D FLT1 56 13 40-50yrs -0.12 -0.88 0.62 743.92 1.00 387 53 10 3 FALSE 0.12
colorectal cancer KRAS_G12D FLT1 128 40 50-65yrs -0.17 -0.93 0.56 734.88 1.00 810 124 36 4 FALSE 0.19
colorectal cancer KRAS_G12D FLT1 85 25 >65yrs -0.18 -0.98 0.55 733.66 1.00 546 83 23 2 FALSE 0.19
non-small cell lung cancer KRAS_G12D FLT1 41 51 50-65yrs -1.22 -3.15 0.30 1242.06 1.00 1229 40 50 1 FALSE 0.80
non-small cell lung cancer KRAS_G12D FLT1 100 80 >65yrs -1.34 -3.06 0.04 1222.45 1.00 1956 99 79 1 FALSE 1.01
uterine cancer KRAS_G12D FLT1 25 35 50-65yrs -1.88 -5.74 0.43 1243.14 1.00 460 25 35 0 FALSE 0.60
uterine cancer KRAS_G12D FLT1 18 13 >65yrs -0.77 -3.67 1.52 1065.00 1.00 445 17 12 1 FALSE 0.25
colorectal cancer KRAS_G12D FLT1 269 78 Age:overall -0.16 -0.91 0.56 741.33 1.00 1743 260 69 9 FALSE 0.17
non-small cell lung cancer KRAS_G12D FLT1 141 131 Age:overall -1.28 -3.17 0.26 1254.71 1.00 3185 139 129 2 FALSE 0.81
uterine cancer KRAS_G12D FLT1 43 48 Age:overall -1.29 -4.52 1.23 1311.58 1.00 905 42 47 1 FALSE 0.41
colorectal cancer KRAS_G12D RPTOR 57 16 40-50yrs -0.42 -1.53 0.45 1035.51 1.00 382 55 14 2 FALSE 0.40
colorectal cancer KRAS_G12D RPTOR 127 23 50-65yrs -0.45 -1.55 0.42 1149.20 1.00 820 125 21 2 FALSE 0.45
colorectal cancer KRAS_G12D RPTOR 84 24 >65yrs -0.44 -1.54 0.41 1078.87 1.00 546 82 22 2 FALSE 0.44
non-small cell lung cancer KRAS_G12D RPTOR 41 22 50-65yrs -4.80 -11.53 -0.40 820.13 1.00 1252 41 22 0 FALSE 0.99
non-small cell lung cancer KRAS_G12D RPTOR 100 40 >65yrs -4.79 -11.46 -0.61 841.14 1.00 1989 100 40 0 FALSE 1.00
colorectal cancer KRAS_G12D RPTOR 268 63 Age:overall -0.43 -1.50 0.42 1066.33 1.00 1748 262 57 6 FALSE 0.44
non-small cell lung cancer KRAS_G12D RPTOR 141 62 Age:overall -4.72 -11.38 -0.50 854.41 1.00 3241 141 62 0 FALSE 1.00
colorectal cancer KRAS_G12D RASA1 56 21 40-50yrs -0.90 -2.06 0.17 1274.36 1.00 381 54 19 2 FALSE 0.93
colorectal cancer KRAS_G12D RASA1 127 24 50-65yrs -0.92 -2.08 0.06 1224.94 1.00 824 125 22 2 FALSE 0.99
colorectal cancer KRAS_G12D RASA1 84 20 >65yrs -1.00 -2.25 0.04 947.48 1.00 550 84 20 0 FALSE 1.06
non-small cell lung cancer KRAS_G12D RASA1 41 26 50-65yrs -0.39 -2.01 1.12 1731.91 1.00 1249 40 25 1 FALSE 0.20
non-small cell lung cancer KRAS_G12D RASA1 100 67 >65yrs -0.51 -1.95 0.62 1240.78 1.00 1965 98 65 2 FALSE 0.36
uterine cancer KRAS_G12D RASA1 25 59 50-65yrs -5.50 -12.29 -1.00 845.62 1.01 451 25 59 0 FALSE 1.15
uterine cancer KRAS_G12D RASA1 18 30 >65yrs -5.42 -12.23 -0.84 847.38 1.01 433 18 30 0 FALSE 1.11
colorectal cancer KRAS_G12D RASA1 267 65 Age:overall -0.95 -2.14 0.07 1197.12 1.00 1755 263 61 4 FALSE 1.02
non-small cell lung cancer KRAS_G12D RASA1 141 93 Age:overall -0.44 -2.08 1.12 1774.19 1.00 3214 138 90 3 FALSE 0.23
uterine cancer KRAS_G12D RASA1 43 89 Age:overall -5.35 -12.22 -0.80 841.06 1.01 884 43 89 0 FALSE 1.11
colorectal cancer KRAS_G12D EPHA5 35 17 <40yrs -0.28 -1.02 0.62 1217.72 1.00 173 30 12 5 FALSE 0.30
colorectal cancer KRAS_G12D EPHA5 56 27 40-50yrs -0.50 -1.29 0.21 1499.20 1.00 378 54 25 2 FALSE 0.72
colorectal cancer KRAS_G12D EPHA5 127 46 50-65yrs -0.66 -1.57 -0.01 1448.08 1.00 801 126 45 1 FALSE 0.98
colorectal cancer KRAS_G12D EPHA5 85 54 >65yrs -0.46 -1.15 0.22 1412.47 1.00 523 80 49 5 FALSE 0.71
non-small cell lung cancer KRAS_G12D EPHA5 41 99 50-65yrs -0.83 -2.30 0.21 1215.43 1.00 1189 40 98 1 FALSE 0.75
non-small cell lung cancer KRAS_G12D EPHA5 100 151 >65yrs -0.61 -1.58 0.22 771.82 1.00 1893 95 146 5 FALSE 0.73
uterine cancer KRAS_G12D EPHA5 11 12 40-50yrs 0.27 -1.22 1.68 1400.09 1.00 74 8 9 3 FALSE 0.15
uterine cancer KRAS_G12D EPHA5 25 50 50-65yrs -0.91 -3.36 0.72 787.79 1.00 455 25 50 0 FALSE 0.44
uterine cancer KRAS_G12D EPHA5 18 32 >65yrs -0.36 -2.19 0.98 1321.54 1.01 434 17 31 1 FALSE 0.19
colorectal cancer KRAS_G12D EPHA5 303 144 Age:overall -0.47 -1.14 0.20 1409.28 1.00 1875 290 131 13 FALSE 0.77
non-small cell lung cancer KRAS_G12D EPHA5 141 250 Age:overall -0.74 -2.06 0.36 1171.68 1.00 3082 135 244 6 FALSE 0.65
uterine cancer KRAS_G12D EPHA5 54 94 Age:overall -0.33 -2.01 1.05 861.47 1.01 963 50 90 4 FALSE 0.17
colorectal cancer KRAS_G12D AR 56 22 40-50yrs -0.90 -1.86 -0.02 1187.76 1.00 376 55 21 1 TRUE 1.18
colorectal cancer KRAS_G12D AR 127 38 50-65yrs -0.91 -1.83 -0.04 1243.96 1.00 805 125 36 2 TRUE 1.31
colorectal cancer KRAS_G12D AR 84 48 >65yrs -0.80 -1.70 0.03 1338.42 1.00 528 80 44 4 TRUE 1.20
non-small cell lung cancer KRAS_G12D AR 41 48 50-65yrs -0.32 -1.91 0.88 1357.96 1.00 1233 40 47 1 TRUE 0.20
non-small cell lung cancer KRAS_G12D AR 100 55 >65yrs -0.14 -1.40 0.92 843.98 1.00 1979 97 52 3 TRUE 0.10
uterine cancer KRAS_G12D AR 25 27 50-65yrs -5.48 -11.10 -0.98 18.10 1.15 467 25 27 0 TRUE 1.17
uterine cancer KRAS_G12D AR 18 29 >65yrs -5.47 -11.00 -0.77 17.46 1.16 431 18 29 0 TRUE 1.17
colorectal cancer KRAS_G12D AR 267 108 Age:overall -0.87 -1.81 -0.05 1256.78 1.00 1709 260 101 7 TRUE 1.29
non-small cell lung cancer KRAS_G12D AR 141 103 Age:overall -0.23 -1.91 1.09 1456.32 1.00 3212 137 99 4 TRUE 0.12
uterine cancer KRAS_G12D AR 43 56 Age:overall -5.43 -10.90 -0.77 17.49 1.17 898 43 56 0 TRUE 1.17
colorectal cancer KRAS_G12D GNAS 63 16 40-50yrs 0.26 -0.46 0.97 751.37 1.00 408 60 13 3 TRUE 0.33
colorectal cancer KRAS_G12D GNAS 147 29 50-65yrs 0.27 -0.41 0.94 706.68 1.00 908 140 22 7 TRUE 0.36
colorectal cancer KRAS_G12D GNAS 95 25 >65yrs 0.22 -0.50 0.90 764.48 1.00 605 93 23 2 TRUE 0.26
pancreatic cancer KRAS_G12D GNAS 205 15 50-65yrs -1.28 -3.30 -0.05 1286.23 1.00 415 204 14 1 TRUE 0.90
pancreatic cancer KRAS_G12D GNAS 260 42 >65yrs -0.12 -0.81 0.53 1241.33 1.00 497 246 28 14 TRUE 0.15
colorectal cancer KRAS_G12D GNAS 305 70 Age:overall 0.25 -0.46 0.95 728.08 1.00 1921 293 58 12 TRUE 0.33
pancreatic cancer KRAS_G12D GNAS 465 57 Age:overall -0.68 -2.55 0.74 1376.79 1.00 912 450 42 15 TRUE 0.40
colorectal cancer KRAS_G12D ASXL2 56 16 40-50yrs -1.23 -2.50 -0.16 366.18 1.01 386 55 15 1 FALSE 1.27
colorectal cancer KRAS_G12D ASXL2 127 26 50-65yrs -1.25 -2.50 -0.17 389.53 1.01 821 126 25 1 FALSE 1.34
colorectal cancer KRAS_G12D ASXL2 84 20 >65yrs -1.24 -2.52 -0.14 374.60 1.01 549 83 19 1 FALSE 1.31
non-small cell lung cancer KRAS_G12D ASXL2 41 22 50-65yrs -1.59 -4.83 0.48 929.98 1.00 1252 41 22 0 FALSE 0.58
non-small cell lung cancer KRAS_G12D ASXL2 100 36 >65yrs -1.33 -4.04 0.47 674.81 1.01 1996 99 35 1 FALSE 0.59
colorectal cancer KRAS_G12D ASXL2 267 62 Age:overall -1.24 -2.50 -0.15 375.49 1.01 1756 264 59 3 FALSE 1.32
non-small cell lung cancer KRAS_G12D ASXL2 141 58 Age:overall -1.45 -4.42 0.58 835.77 1.01 3248 140 57 1 FALSE 0.59
colorectal cancer KRAS_G12D SF3B1 56 16 40-50yrs -0.91 -2.18 0.18 202.57 1.02 382 56 16 0 TRUE 0.90
colorectal cancer KRAS_G12D SF3B1 127 24 50-65yrs -0.91 -2.18 0.18 179.14 1.02 821 126 23 1 TRUE 0.92
colorectal cancer KRAS_G12D SF3B1 84 24 >65yrs -0.83 -2.06 0.19 209.76 1.02 551 81 21 3 TRUE 0.85
non-small cell lung cancer KRAS_G12D SF3B1 41 36 50-65yrs -0.74 -2.74 0.78 1426.50 1.00 1239 40 35 1 TRUE 0.39
non-small cell lung cancer KRAS_G12D SF3B1 100 49 >65yrs -0.88 -2.80 0.49 1265.82 1.00 1985 99 48 1 TRUE 0.52
colorectal cancer KRAS_G12D SF3B1 267 64 Age:overall -0.88 -2.11 0.18 197.66 1.02 1754 263 60 4 TRUE 0.92
non-small cell lung cancer KRAS_G12D SF3B1 141 85 Age:overall -0.80 -2.87 0.72 1475.38 1.00 3224 139 83 2 TRUE 0.42
colorectal cancer KRAS_G12D MLH1 147 25 50-65yrs -0.77 -2.14 0.40 925.87 1.00 908 145 23 2 TRUE 0.61
colorectal cancer KRAS_G12D MLH1 95 12 >65yrs -0.77 -2.27 0.47 889.48 1.00 617 94 11 1 TRUE 0.55
colorectal cancer KRAS_G12D MLH1 242 37 Age:overall -0.78 -2.25 0.45 856.50 1.00 1525 239 34 3 TRUE 0.56
colorectal cancer KRAS_G12D ROS1 56 19 40-50yrs -1.09 -2.20 -0.24 426.09 1.00 378 56 19 0 TRUE 1.49
colorectal cancer KRAS_G12D ROS1 127 43 50-65yrs -1.07 -2.14 -0.21 468.20 1.00 808 125 41 2 TRUE 1.52
colorectal cancer KRAS_G12D ROS1 84 31 >65yrs -1.04 -2.09 -0.19 497.02 1.00 542 81 28 3 TRUE 1.43
non-small cell lung cancer KRAS_G12D ROS1 41 37 50-65yrs -2.12 -5.42 -0.07 991.25 1.00 1237 41 37 0 TRUE 0.93
non-small cell lung cancer KRAS_G12D ROS1 100 66 >65yrs -1.94 -4.70 -0.21 837.38 1.00 1968 99 65 1 TRUE 0.98
uterine cancer KRAS_G12D ROS1 10 16 40-50yrs -0.36 -1.88 1.03 1325.10 1.00 75 8 14 2 TRUE 0.20
uterine cancer KRAS_G12D ROS1 25 45 50-65yrs -1.10 -3.16 0.33 1337.12 1.00 465 25 45 0 TRUE 0.66
uterine cancer KRAS_G12D ROS1 18 34 >65yrs -0.67 -2.49 0.72 1420.53 1.00 440 17 33 1 TRUE 0.40
colorectal cancer KRAS_G12D ROS1 267 93 Age:overall -1.07 -2.12 -0.22 444.35 1.00 1728 262 88 5 TRUE 1.50
non-small cell lung cancer KRAS_G12D ROS1 141 103 Age:overall -1.99 -5.07 -0.02 866.49 1.00 3205 140 102 1 TRUE 0.91
uterine cancer KRAS_G12D ROS1 53 95 Age:overall -0.69 -2.35 0.67 1229.12 1.00 980 50 92 3 TRUE 0.43
colorectal cancer KRAS_G12D PIK3R2 56 11 40-50yrs -0.56 -1.95 0.57 783.88 1.00 386 55 10 1 FALSE 0.39
colorectal cancer KRAS_G12D PIK3R2 127 13 50-65yrs -0.69 -2.29 0.42 473.03 1.00 827 127 13 0 FALSE 0.50
colorectal cancer KRAS_G12D PIK3R2 84 21 >65yrs -0.45 -1.72 0.55 837.49 1.00 549 81 18 3 FALSE 0.34
colorectal cancer KRAS_G12D PIK3R2 267 45 Age:overall -0.56 -1.91 0.49 678.53 1.00 1762 263 41 4 FALSE 0.43
colorectal cancer KRAS_G12D FLT3 147 17 50-65yrs -0.71 -2.31 0.49 1417.51 1.00 913 146 16 1 TRUE 0.50
colorectal cancer KRAS_G12D FLT3 95 17 >65yrs -0.59 -1.98 0.65 1435.81 1.00 612 93 15 2 TRUE 0.41
non-small cell lung cancer KRAS_G12D FLT3 42 31 50-65yrs -0.72 -3.76 0.90 1427.80 1.00 1303 42 31 0 TRUE 0.25
non-small cell lung cancer KRAS_G12D FLT3 105 44 >65yrs -0.08 -1.53 1.04 1275.69 1.00 2039 102 41 3 TRUE 0.05
uterine cancer KRAS_G12D FLT3 9 16 40-50yrs -1.40 -4.37 0.70 1248.43 1.00 78 8 15 1 TRUE 0.57
uterine cancer KRAS_G12D FLT3 26 23 50-65yrs -2.10 -5.67 0.25 1196.38 1.00 535 26 23 0 TRUE 0.76
uterine cancer KRAS_G12D FLT3 19 17 >65yrs -2.02 -5.40 0.40 1325.33 1.00 486 19 17 0 TRUE 0.75
colorectal cancer KRAS_G12D FLT3 242 34 Age:overall -0.66 -2.25 0.65 1422.95 1.00 1525 239 31 3 TRUE 0.42
non-small cell lung cancer KRAS_G12D FLT3 147 75 Age:overall -0.37 -2.39 1.18 1567.22 1.00 3342 144 72 3 TRUE 0.16
uterine cancer KRAS_G12D FLT3 54 56 Age:overall -1.80 -4.84 0.36 1163.62 1.00 1099 53 55 1 TRUE 0.76
colorectal cancer KRAS_G12D MSH2 56 24 40-50yrs -0.81 -1.97 0.04 738.85 1.01 381 55 23 1 TRUE 0.94
colorectal cancer KRAS_G12D MSH2 127 26 50-65yrs -0.74 -1.82 0.13 659.96 1.00 821 124 23 3 TRUE 0.91
colorectal cancer KRAS_G12D MSH2 84 23 >65yrs -0.81 -1.97 0.06 851.57 1.01 550 83 22 1 TRUE 0.95
non-small cell lung cancer KRAS_G12D MSH2 41 18 50-65yrs -0.69 -3.17 0.96 1373.25 1.00 1257 41 18 0 TRUE 0.26
non-small cell lung cancer KRAS_G12D MSH2 100 37 >65yrs -0.34 -2.17 0.99 1273.27 1.00 1996 98 35 2 TRUE 0.17
uterine cancer KRAS_G12D MSH2 25 41 50-65yrs -0.52 -2.62 0.79 40.52 1.07 461 24 40 1 TRUE 0.24
uterine cancer KRAS_G12D MSH2 18 16 >65yrs -0.25 -2.50 1.47 242.61 1.02 444 17 15 1 TRUE 0.09
colorectal cancer KRAS_G12D MSH2 267 73 Age:overall -0.78 -1.94 0.09 618.45 1.01 1752 262 68 5 TRUE 0.96
non-small cell lung cancer KRAS_G12D MSH2 141 55 Age:overall -0.49 -2.68 1.21 1426.61 1.00 3253 139 53 2 TRUE 0.21
uterine cancer KRAS_G12D MSH2 43 57 Age:overall -0.36 -2.63 1.47 161.21 1.03 905 41 55 2 TRUE 0.13
non-small cell lung cancer KRAS_G12D DIS3 41 27 50-65yrs -0.43 -2.38 1.01 1600.74 1.00 1248 40 26 1 FALSE 0.21
non-small cell lung cancer KRAS_G12D DIS3 100 34 >65yrs -0.54 -2.51 0.85 1524.17 1.00 1997 99 33 1 FALSE 0.28
non-small cell lung cancer KRAS_G12D DIS3 141 61 Age:overall -0.48 -2.43 1.11 1583.67 1.00 3245 139 59 2 FALSE 0.23
colorectal cancer KRAS_G12D AXL 35 13 <40yrs -0.59 -1.50 0.16 254.89 1.00 173 34 12 1 FALSE 0.75
colorectal cancer KRAS_G12D AXL 56 16 40-50yrs -0.62 -1.57 0.08 213.84 1.01 382 56 16 0 FALSE 0.79
colorectal cancer KRAS_G12D AXL 127 30 50-65yrs -0.60 -1.50 0.07 224.57 1.01 817 125 28 2 FALSE 0.80
colorectal cancer KRAS_G12D AXL 84 29 >65yrs -0.54 -1.43 0.20 286.48 1.01 543 80 25 4 FALSE 0.70
colorectal cancer KRAS_G12D AXL 302 88 Age:overall -0.58 -1.44 0.11 227.19 1.01 1915 295 81 7 FALSE 0.79
pancreatic cancer KRAS_G12D DAXX 191 23 50-65yrs -2.59 -5.00 -1.46 7.97 1.12 377 191 23 0 TRUE 2.40
pancreatic cancer KRAS_G12D DAXX 247 21 >65yrs -2.35 -3.96 -1.18 28.09 1.06 469 245 19 2 TRUE 3.07
pancreatic cancer KRAS_G12D DAXX 438 44 Age:overall -2.45 -4.25 -1.24 14.86 1.08 846 436 42 2 TRUE 2.63
colorectal cancer KRAS_G12D PIK3CG 56 22 40-50yrs -0.05 -0.85 0.62 666.05 1.00 379 54 20 2 FALSE 0.05
colorectal cancer KRAS_G12D PIK3CG 129 37 50-65yrs 0.04 -0.61 0.66 1013.80 1.00 814 122 30 7 FALSE 0.05
colorectal cancer KRAS_G12D PIK3CG 84 42 >65yrs -0.06 -0.82 0.54 448.51 1.01 530 80 38 4 FALSE 0.06
non-small cell lung cancer KRAS_G12D PIK3CG 41 69 50-65yrs -1.91 -4.76 -0.20 1118.22 1.00 1211 41 69 0 FALSE 1.01
non-small cell lung cancer KRAS_G12D PIK3CG 100 105 >65yrs -1.55 -3.36 -0.18 1046.28 1.00 1938 98 103 2 FALSE 1.22
uterine cancer KRAS_G12D PIK3CG 25 28 50-65yrs -1.14 -3.79 0.75 1339.92 1.00 466 24 27 1 FALSE 0.47
uterine cancer KRAS_G12D PIK3CG 18 16 >65yrs -1.39 -4.43 0.80 1344.32 1.00 443 18 16 0 FALSE 0.50
colorectal cancer KRAS_G12D PIK3CG 269 101 Age:overall -0.02 -0.71 0.62 819.69 1.00 1723 256 88 13 FALSE 0.02
non-small cell lung cancer KRAS_G12D PIK3CG 141 174 Age:overall -1.72 -3.87 -0.06 1190.55 1.00 3149 139 172 2 FALSE 1.06
uterine cancer KRAS_G12D PIK3CG 43 44 Age:overall -1.25 -4.13 0.91 1377.54 1.00 909 42 43 1 FALSE 0.48
colorectal cancer KRAS_G12D MAP2K4 56 11 40-50yrs -0.88 -2.16 0.16 689.58 1.00 383 56 11 0 TRUE 0.86
colorectal cancer KRAS_G12D MAP2K4 127 29 50-65yrs -0.88 -2.09 0.12 583.02 1.00 814 126 28 1 TRUE 0.91
colorectal cancer KRAS_G12D MAP2K4 85 18 >65yrs -0.79 -1.97 0.25 600.70 1.00 550 82 15 3 TRUE 0.77
colorectal cancer KRAS_G12D MAP2K4 268 58 Age:overall -0.85 -2.09 0.17 631.03 1.00 1747 264 54 4 TRUE 0.86
colorectal cancer KRAS_G12D EGFR 63 12 40-50yrs -1.28 -2.74 -0.15 1070.04 1.00 411 62 11 1 TRUE 1.28
colorectal cancer KRAS_G12D EGFR 147 27 50-65yrs -1.28 -2.70 -0.17 1142.38 1.00 904 145 25 2 TRUE 1.30
colorectal cancer KRAS_G12D EGFR 95 23 >65yrs -1.32 -2.83 -0.17 1065.20 1.00 606 95 23 0 TRUE 1.34
non-small cell lung cancer KRAS_G12D EGFR 8 68 40-50yrs -3.11 -4.58 -1.96 1300.70 1.00 139 8 68 0 TRUE 5.25
non-small cell lung cancer KRAS_G12D EGFR 42 403 50-65yrs -3.16 -4.69 -2.05 1309.55 1.00 991 42 403 0 TRUE 5.61
non-small cell lung cancer KRAS_G12D EGFR 104 550 >65yrs -3.02 -4.41 -1.95 1365.72 1.00 1638 101 547 3 TRUE 5.92
colorectal cancer KRAS_G12D EGFR 305 62 Age:overall -1.29 -2.73 -0.16 1098.49 1.00 1921 302 59 3 TRUE 1.33
non-small cell lung cancer KRAS_G12D EGFR 157 1042 Age:overall -3.10 -4.53 -2.04 1334.74 1.00 2812 154 1039 3 TRUE 6.00
colorectal cancer KRAS_G12D ARID1B 35 11 <40yrs -0.99 -1.84 -0.15 1209.17 1.00 176 34 10 1 TRUE 1.69
colorectal cancer KRAS_G12D ARID1B 57 22 40-50yrs -0.89 -1.75 0.03 1390.93 1.00 382 53 18 4 TRUE 1.33
colorectal cancer KRAS_G12D ARID1B 127 54 50-65yrs -1.09 -1.97 -0.37 1079.54 1.00 795 126 53 1 TRUE 2.06
colorectal cancer KRAS_G12D ARID1B 84 53 >65yrs -1.04 -1.83 -0.33 1087.94 1.00 518 82 51 2 TRUE 2.08
non-small cell lung cancer KRAS_G12D ARID1B 41 43 50-65yrs -1.02 -3.72 0.54 1292.67 1.00 1233 41 43 0 TRUE 0.41
non-small cell lung cancer KRAS_G12D ARID1B 100 64 >65yrs -0.47 -1.97 0.69 1369.50 1.00 1971 97 61 3 TRUE 0.32
uterine cancer KRAS_G12D ARID1B 9 13 40-50yrs 0.84 -0.23 1.66 20.43 1.07 73 7 11 2 TRUE 1.06
uterine cancer KRAS_G12D ARID1B 26 58 50-65yrs 0.88 -0.08 1.50 9.70 1.12 451 20 52 6 TRUE 1.38
uterine cancer KRAS_G12D ARID1B 18 39 >65yrs 0.75 -0.36 1.40 9.69 1.13 424 16 37 2 TRUE 0.90
colorectal cancer KRAS_G12D ARID1B 303 140 Age:overall -1.00 -1.78 -0.30 1160.11 1.00 1871 295 132 8 TRUE 2.07
non-small cell lung cancer KRAS_G12D ARID1B 141 107 Age:overall -0.72 -2.69 0.75 1403.20 1.00 3204 138 104 3 TRUE 0.38
uterine cancer KRAS_G12D ARID1B 53 110 Age:overall 0.81 -0.19 1.43 11.60 1.11 948 43 100 10 TRUE 1.12
non-small cell lung cancer KRAS_G12D INSR 41 23 50-65yrs -1.51 -5.40 0.58 751.67 1.00 1248 41 23 0 FALSE 0.50
non-small cell lung cancer KRAS_G12D INSR 100 28 >65yrs -1.21 -4.27 0.70 537.10 1.01 1994 99 27 1 FALSE 0.48
non-small cell lung cancer KRAS_G12D INSR 141 51 Age:overall -1.32 -4.76 0.74 554.09 1.00 3242 140 50 1 FALSE 0.49
non-small cell lung cancer KRAS_G12D NKX2-1 41 31 50-65yrs 0.71 -0.92 1.76 1313.29 1.00 1247 40 30 1 TRUE 0.53
non-small cell lung cancer KRAS_G12D NKX2-1 102 42 >65yrs 1.32 0.48 2.10 1280.07 1.00 1999 94 34 8 TRUE 2.90
non-small cell lung cancer KRAS_G12D NKX2-1 143 73 Age:overall 1.02 -0.58 2.25 1122.75 1.00 3246 134 64 9 TRUE 0.80
colorectal cancer KRAS_G12D ARID5B 56 20 40-50yrs -0.33 -1.65 0.58 1001.52 1.00 383 56 20 0 FALSE 0.24
colorectal cancer KRAS_G12D ARID5B 128 22 50-65yrs -0.12 -1.10 0.77 1062.15 1.00 823 124 18 4 FALSE 0.10
colorectal cancer KRAS_G12D ARID5B 85 17 >65yrs -0.14 -1.11 0.76 1024.32 1.00 552 82 14 3 FALSE 0.11
uterine cancer KRAS_G12D ARID5B 11 14 40-50yrs 1.09 -0.17 2.40 1544.77 1.00 73 7 10 4 FALSE 1.05
uterine cancer KRAS_G12D ARID5B 25 44 50-65yrs -0.06 -1.63 1.16 1385.15 1.00 455 24 43 1 FALSE 0.03
uterine cancer KRAS_G12D ARID5B 18 20 >65yrs 0.72 -0.60 1.90 1513.77 1.00 440 16 18 2 FALSE 0.56
colorectal cancer KRAS_G12D ARID5B 269 59 Age:overall -0.19 -1.19 0.66 1070.79 1.01 1758 262 52 7 FALSE 0.16
uterine cancer KRAS_G12D ARID5B 54 78 Age:overall 0.59 -0.74 1.90 1592.71 1.00 968 47 71 7 FALSE 0.41
non-small cell lung cancer KRAS_G12D WT1 41 30 50-65yrs 0.35 -1.24 1.51 1105.12 1.00 1245 40 29 1 TRUE 0.21
non-small cell lung cancer KRAS_G12D WT1 101 36 >65yrs 0.65 -0.45 1.63 1405.81 1.00 1999 97 32 4 TRUE 0.65
non-small cell lung cancer KRAS_G12D WT1 142 66 Age:overall 0.51 -0.87 1.78 1305.45 1.00 3244 137 61 5 TRUE 0.34
non-small cell lung cancer KRAS_G12D MET 42 48 50-65yrs -0.58 -2.25 1.00 1451.30 1.00 1292 40 46 2 TRUE 0.31
non-small cell lung cancer KRAS_G12D MET 104 111 >65yrs -1.27 -2.89 -0.09 1286.61 1.00 1978 103 110 1 TRUE 1.06
uterine cancer KRAS_G12D MET 26 29 50-65yrs -0.18 -2.06 1.26 1411.88 1.00 533 24 27 2 TRUE 0.08
uterine cancer KRAS_G12D MET 19 20 >65yrs -0.59 -3.35 1.08 1267.86 1.00 485 19 20 0 TRUE 0.21
non-small cell lung cancer KRAS_G12D MET 146 159 Age:overall -0.91 -2.85 0.74 1421.51 1.00 3270 143 156 3 TRUE 0.51
uterine cancer KRAS_G12D MET 45 49 Age:overall -0.38 -2.66 1.28 1368.71 1.00 1018 43 47 2 TRUE 0.16
non-small cell lung cancer KRAS_G12D PMS1 41 17 50-65yrs -0.24 -2.16 1.39 1231.28 1.00 1258 40 16 1 TRUE 0.10
non-small cell lung cancer KRAS_G12D PMS1 100 35 >65yrs -0.43 -2.32 0.98 1091.03 1.00 1995 99 34 1 TRUE 0.22
non-small cell lung cancer KRAS_G12D PMS1 141 52 Age:overall -0.32 -2.29 1.32 1347.64 1.00 3253 139 50 2 TRUE 0.14
pancreatic cancer KRAS_G12D MEN1 200 39 50-65yrs -4.12 -7.43 -2.17 760.78 1.00 378 200 39 0 TRUE 2.58
pancreatic cancer KRAS_G12D MEN1 254 28 >65yrs -3.76 -6.41 -1.84 705.46 1.00 477 253 27 1 TRUE 2.67
pancreatic cancer KRAS_G12D MEN1 454 67 Age:overall -3.87 -6.72 -1.83 829.64 1.00 855 453 66 1 TRUE 2.56
non-small cell lung cancer KRAS_G12D PIK3C3 41 29 50-65yrs -1.73 -4.86 0.28 1007.93 1.00 1240 41 29 0 FALSE 0.67
non-small cell lung cancer KRAS_G12D PIK3C3 100 44 >65yrs -1.50 -4.19 0.30 1137.49 1.00 1979 99 43 1 FALSE 0.73
non-small cell lung cancer KRAS_G12D PIK3C3 141 73 Age:overall -1.60 -4.66 0.42 1043.72 1.00 3219 140 72 1 FALSE 0.70
colorectal cancer KRAS_G12D BRAF 38 21 <40yrs -2.24 -3.36 -1.22 1542.19 1.00 179 37 20 1 TRUE 4.31
colorectal cancer KRAS_G12D BRAF 63 34 40-50yrs -2.35 -3.52 -1.30 1501.89 1.00 389 63 34 0 TRUE 4.38
colorectal cancer KRAS_G12D BRAF 147 93 50-65yrs -2.27 -3.39 -1.33 1451.52 1.00 838 145 91 2 TRUE 4.98
colorectal cancer KRAS_G12D BRAF 96 105 >65yrs -2.27 -3.35 -1.36 1210.94 1.00 530 94 103 2 TRUE 5.05
non-small cell lung cancer KRAS_G12D BRAF 42 62 50-65yrs -1.35 -4.46 0.16 1345.45 1.00 1270 42 62 0 TRUE 0.58
non-small cell lung cancer KRAS_G12D BRAF 104 122 >65yrs -0.73 -1.87 0.24 1439.61 1.00 1963 100 118 4 TRUE 0.72
colorectal cancer KRAS_G12D BRAF 344 253 Age:overall -2.28 -3.32 -1.38 1439.70 1.00 1936 339 248 5 TRUE 5.31
non-small cell lung cancer KRAS_G12D BRAF 146 184 Age:overall -1.02 -3.07 0.46 1428.76 1.00 3233 142 180 4 TRUE 0.57
colorectal cancer KRAS_G12D B2M 35 12 <40yrs -0.15 -0.83 0.46 933.00 1.01 168 32 9 3 FALSE 0.19
colorectal cancer KRAS_G12D B2M 54 21 40-50yrs -0.26 -0.99 0.34 1134.12 1.00 372 53 20 1 FALSE 0.35
colorectal cancer KRAS_G12D B2M 126 52 50-65yrs -0.14 -0.74 0.44 864.37 1.01 787 118 44 8 FALSE 0.20
colorectal cancer KRAS_G12D B2M 83 54 >65yrs -0.24 -0.88 0.32 1182.92 1.00 522 79 50 4 FALSE 0.36
colorectal cancer KRAS_G12D B2M 298 139 Age:overall -0.20 -0.82 0.34 1108.45 1.00 1849 282 123 16 FALSE 0.29
colorectal cancer KRAS_G12D TGFBR1 35 11 <40yrs 0.60 -0.41 1.68 1036.92 1.00 170 31 7 4 FALSE 0.59
colorectal cancer KRAS_G12D TGFBR1 122 18 50-65yrs 0.07 -1.22 0.97 1345.97 1.00 803 121 17 1 FALSE 0.05
colorectal cancer KRAS_G12D TGFBR1 81 13 >65yrs 0.41 -0.61 1.34 1089.83 1.00 542 78 10 3 FALSE 0.40
non-small cell lung cancer KRAS_G12D TGFBR1 41 16 50-65yrs -0.10 -2.09 1.50 1261.93 1.00 1253 40 15 1 FALSE 0.04
non-small cell lung cancer KRAS_G12D TGFBR1 100 31 >65yrs -0.29 -2.18 1.19 1184.64 1.00 1991 99 30 1 FALSE 0.13
colorectal cancer KRAS_G12D TGFBR1 238 42 Age:overall 0.37 -0.61 1.30 1168.40 1.00 1515 230 34 8 FALSE 0.34
non-small cell lung cancer KRAS_G12D TGFBR1 141 47 Age:overall -0.18 -2.21 1.41 1282.41 1.00 3244 139 45 2 FALSE 0.07
colorectal cancer KRAS_G12D TET2 35 16 <40yrs -0.31 -1.23 0.41 555.46 1.01 172 34 15 1 TRUE 0.34
colorectal cancer KRAS_G12D TET2 56 19 40-50yrs -0.33 -1.23 0.38 499.09 1.00 381 55 18 1 TRUE 0.37
colorectal cancer KRAS_G12D TET2 128 29 50-65yrs -0.20 -1.03 0.51 586.40 1.00 819 122 23 6 TRUE 0.22
colorectal cancer KRAS_G12D TET2 84 27 >65yrs -0.32 -1.18 0.34 420.98 1.00 545 82 25 2 TRUE 0.38
non-small cell lung cancer KRAS_G12D TET2 41 33 50-65yrs -0.65 -3.22 0.84 846.92 1.00 1244 41 33 0 TRUE 0.25
non-small cell lung cancer KRAS_G12D TET2 100 45 >65yrs -0.12 -1.58 1.00 965.00 1.00 1988 97 42 3 TRUE 0.07
uterine cancer KRAS_G12D TET2 9 11 40-50yrs -0.25 -2.03 1.23 1310.77 1.00 76 8 10 1 TRUE 0.12
uterine cancer KRAS_G12D TET2 25 30 50-65yrs -0.16 -1.78 1.05 1337.93 1.00 466 23 28 2 TRUE 0.08
uterine cancer KRAS_G12D TET2 18 22 >65yrs -0.55 -2.64 0.92 1400.48 1.00 437 18 22 0 TRUE 0.25
colorectal cancer KRAS_G12D TET2 303 91 Age:overall -0.29 -1.07 0.37 505.64 1.00 1917 293 81 10 TRUE 0.35
non-small cell lung cancer KRAS_G12D TET2 141 78 Age:overall -0.37 -2.48 1.17 875.63 1.00 3232 138 75 3 TRUE 0.16
uterine cancer KRAS_G12D TET2 52 63 Age:overall -0.30 -2.01 1.10 1300.01 1.00 979 49 60 3 TRUE 0.15
colorectal cancer KRAS_G12D PDGFRB 56 11 40-50yrs -0.36 -1.69 0.76 1128.20 1.00 384 55 10 1 TRUE 0.26
colorectal cancer KRAS_G12D PDGFRB 127 11 50-65yrs -0.40 -1.75 0.66 1161.68 1.00 830 126 10 1 TRUE 0.31
colorectal cancer KRAS_G12D PDGFRB 84 24 >65yrs -0.26 -1.39 0.67 1090.43 1.00 544 81 21 3 TRUE 0.22
non-small cell lung cancer KRAS_G12D PDGFRB 41 33 50-65yrs -1.83 -5.03 0.15 550.73 1.00 1244 41 33 0 TRUE 0.76
non-small cell lung cancer KRAS_G12D PDGFRB 100 55 >65yrs -1.65 -4.21 0.12 543.97 1.00 1980 99 54 1 TRUE 0.81
colorectal cancer KRAS_G12D PDGFRB 267 46 Age:overall -0.35 -1.55 0.70 1254.25 1.00 1758 262 41 5 TRUE 0.27
non-small cell lung cancer KRAS_G12D PDGFRB 141 88 Age:overall -1.72 -4.47 0.18 520.22 1.00 3224 140 87 1 TRUE 0.77
colorectal cancer KRAS_G12D CARD11 35 21 <40yrs -0.20 -0.96 0.46 1336.22 1.00 166 32 18 3 FALSE 0.25
colorectal cancer KRAS_G12D CARD11 56 20 40-50yrs -0.22 -0.93 0.43 1396.73 1.00 379 53 17 3 FALSE 0.28
colorectal cancer KRAS_G12D CARD11 128 45 50-65yrs -0.22 -0.92 0.41 1164.56 1.00 804 122 39 6 FALSE 0.30
colorectal cancer KRAS_G12D CARD11 84 42 >65yrs -0.34 -1.15 0.26 1228.07 1.00 530 82 40 2 FALSE 0.46
non-small cell lung cancer KRAS_G12D CARD11 41 50 50-65yrs -1.17 -4.47 0.29 999.97 1.00 1225 41 50 0 FALSE 0.46
non-small cell lung cancer KRAS_G12D CARD11 100 75 >65yrs -0.60 -1.96 0.54 1232.39 1.00 1962 97 72 3 FALSE 0.46
uterine cancer KRAS_G12D CARD11 25 26 50-65yrs -1.48 -4.57 0.54 875.83 1.00 465 25 26 0 FALSE 0.60
uterine cancer KRAS_G12D CARD11 18 23 >65yrs -1.13 -3.83 0.84 869.59 1.00 437 17 22 1 FALSE 0.47
colorectal cancer KRAS_G12D CARD11 303 128 Age:overall -0.25 -0.94 0.36 1174.48 1.00 1879 289 114 14 FALSE 0.36
non-small cell lung cancer KRAS_G12D CARD11 141 125 Age:overall -0.90 -3.09 0.60 1231.48 1.00 3187 138 122 3 FALSE 0.46
uterine cancer KRAS_G12D CARD11 43 49 Age:overall -1.30 -4.07 0.78 883.57 1.00 902 42 48 1 FALSE 0.53
colorectal cancer KRAS_G12D DNMT3A 56 11 40-50yrs -2.35 -4.44 -0.63 246.74 1.01 385 56 11 0 TRUE 2.15
colorectal cancer KRAS_G12D DNMT3A 127 21 50-65yrs -2.33 -4.32 -0.64 216.78 1.01 821 126 20 1 TRUE 2.14
colorectal cancer KRAS_G12D DNMT3A 84 19 >65yrs -2.34 -4.45 -0.68 225.91 1.01 550 84 19 0 TRUE 2.14
non-small cell lung cancer KRAS_G12D DNMT3A 41 30 50-65yrs 0.10 -1.45 1.30 1219.00 1.00 1245 40 29 1 TRUE 0.05
non-small cell lung cancer KRAS_G12D DNMT3A 100 42 >65yrs 0.19 -1.03 1.25 1281.34 1.00 1990 97 39 3 TRUE 0.13
colorectal cancer KRAS_G12D DNMT3A 267 51 Age:overall -2.34 -4.40 -0.67 223.09 1.01 1756 266 50 1 TRUE 2.16
non-small cell lung cancer KRAS_G12D DNMT3A 141 72 Age:overall 0.12 -1.39 1.33 1353.21 1.00 3235 137 68 4 TRUE 0.07
colorectal cancer KRAS_G12D MSH6 36 12 <40yrs -0.08 -0.85 0.83 977.45 1.00 175 31 7 5 TRUE 0.07
colorectal cancer KRAS_G12D MSH6 56 24 40-50yrs -0.19 -0.95 0.50 944.01 1.00 378 53 21 3 TRUE 0.22
colorectal cancer KRAS_G12D MSH6 127 38 50-65yrs -0.37 -1.40 0.29 822.77 1.00 812 127 38 0 TRUE 0.40
colorectal cancer KRAS_G12D MSH6 85 26 >65yrs -0.22 -1.02 0.46 973.40 1.00 544 82 23 3 TRUE 0.26
uterine cancer KRAS_G12D MSH6 10 13 40-50yrs 0.73 -0.36 1.83 1345.80 1.00 72 7 10 3 TRUE 0.71
uterine cancer KRAS_G12D MSH6 26 38 50-65yrs 0.48 -0.55 1.41 1433.65 1.00 462 23 35 3 TRUE 0.46
uterine cancer KRAS_G12D MSH6 18 35 >65yrs 0.29 -1.12 1.31 1364.51 1.00 433 17 34 1 TRUE 0.20
colorectal cancer KRAS_G12D MSH6 304 100 Age:overall -0.22 -0.96 0.43 928.72 1.00 1909 293 89 11 TRUE 0.27
uterine cancer KRAS_G12D MSH6 54 86 Age:overall 0.51 -0.63 1.51 1504.81 1.00 967 47 79 7 TRUE 0.46
non-small cell lung cancer KRAS_G12D MAX 41 15 50-65yrs 1.45 0.28 2.46 1401.68 1.00 1255 39 13 2 FALSE 2.11
non-small cell lung cancer KRAS_G12D MAX 100 39 >65yrs 1.51 0.66 2.25 1216.62 1.00 1990 93 32 7 FALSE 3.85
non-small cell lung cancer KRAS_G12D MAX 141 54 Age:overall 1.47 0.30 2.71 1329.19 1.00 3245 132 45 9 FALSE 1.75
non-small cell lung cancer KRAS_G12D INPP4B 42 46 50-65yrs 0.80 -0.05 1.65 1138.48 1.00 1234 38 42 4 FALSE 1.14
non-small cell lung cancer KRAS_G12D INPP4B 100 76 >65yrs 0.66 -0.11 1.36 1144.33 1.00 1966 94 70 6 FALSE 1.13
non-small cell lung cancer KRAS_G12D INPP4B 142 122 Age:overall 0.72 -0.26 1.66 1195.88 1.00 3200 132 112 10 FALSE 0.83
non-small cell lung cancer KRAS_G12D NFE2L2 41 39 50-65yrs -1.08 -3.02 0.56 1303.19 1.00 1238 40 38 1 FALSE 0.62
non-small cell lung cancer KRAS_G12D NFE2L2 100 85 >65yrs -1.31 -3.32 0.04 1224.20 1.00 1955 99 84 1 FALSE 0.91
non-small cell lung cancer KRAS_G12D NFE2L2 141 124 Age:overall -1.20 -3.26 0.42 1376.47 1.00 3193 139 122 2 FALSE 0.66
uterine cancer KRAS_G12D SPOP 25 25 50-65yrs -1.21 -4.19 0.71 926.29 1.00 463 24 24 1 FALSE 0.49
uterine cancer KRAS_G12D SPOP 18 26 >65yrs -1.45 -4.85 0.63 850.17 1.00 431 18 26 0 FALSE 0.53
uterine cancer KRAS_G12D SPOP 43 51 Age:overall -1.32 -4.41 0.63 859.12 1.00 894 42 50 1 FALSE 0.51
colorectal cancer KRAS_G12D SOX9 35 22 <40yrs 0.11 -0.34 0.52 821.12 1.00 165 32 19 3 FALSE 0.19
colorectal cancer KRAS_G12D SOX9 56 41 40-50yrs 0.11 -0.33 0.52 915.17 1.00 360 50 35 6 FALSE 0.22
colorectal cancer KRAS_G12D SOX9 130 114 50-65yrs 0.14 -0.26 0.52 706.83 1.00 757 112 96 18 FALSE 0.32
colorectal cancer KRAS_G12D SOX9 85 87 >65yrs 0.13 -0.28 0.52 687.94 1.00 495 73 75 12 FALSE 0.27
colorectal cancer KRAS_G12D SOX9 306 264 Age:overall 0.12 -0.28 0.50 604.90 1.00 1777 267 225 39 FALSE 0.27
colorectal cancer KRAS_G12D ETV1 122 15 50-65yrs -1.17 -3.18 0.39 737.15 1.00 805 121 14 1 TRUE 0.71
colorectal cancer KRAS_G12D ETV1 81 23 >65yrs -1.26 -3.21 0.18 1091.19 1.00 532 80 22 1 TRUE 0.83
colorectal cancer KRAS_G12D ETV1 203 38 Age:overall -1.21 -3.23 0.48 854.06 1.00 1337 201 36 2 TRUE 0.68
colorectal cancer KRAS_G12D ARAF 127 22 50-65yrs -1.49 -4.55 0.03 969.28 1.00 821 127 22 0 FALSE 0.59
colorectal cancer KRAS_G12D ARAF 84 23 >65yrs -0.68 -2.16 0.55 1158.75 1.00 547 81 20 3 FALSE 0.48
non-small cell lung cancer KRAS_G12D ARAF 41 26 50-65yrs -0.90 -3.50 0.76 1077.80 1.00 1252 41 26 0 FALSE 0.39
non-small cell lung cancer KRAS_G12D ARAF 100 42 >65yrs -0.52 -2.28 0.78 968.80 1.00 1993 98 40 2 FALSE 0.30
colorectal cancer KRAS_G12D ARAF 211 45 Age:overall -1.04 -3.27 0.70 1093.49 1.00 1368 208 42 3 FALSE 0.52
non-small cell lung cancer KRAS_G12D ARAF 141 68 Age:overall -0.71 -2.83 0.96 1096.74 1.00 3245 139 66 2 FALSE 0.34
non-small cell lung cancer KRAS_G12D JAK2 42 38 50-65yrs -1.24 -4.85 0.60 1155.82 1.00 1296 42 38 0 TRUE 0.39
non-small cell lung cancer KRAS_G12D JAK2 104 35 >65yrs -0.44 -2.31 0.92 1445.81 1.00 2046 102 33 2 TRUE 0.23
non-small cell lung cancer KRAS_G12D JAK2 146 73 Age:overall -0.81 -3.45 1.04 1181.12 1.00 3342 144 71 2 TRUE 0.32
colorectal cancer KRAS_G12D SMAD2 57 33 40-50yrs 0.31 -0.32 1.02 46.94 1.06 373 51 27 6 TRUE 0.40
colorectal cancer KRAS_G12D SMAD2 128 39 50-65yrs 0.26 -0.32 0.91 54.46 1.06 811 121 32 7 TRUE 0.36
colorectal cancer KRAS_G12D SMAD2 84 20 >65yrs 0.21 -0.53 0.95 79.31 1.04 548 81 17 3 TRUE 0.24
colorectal cancer KRAS_G12D SMAD2 269 92 Age:overall 0.26 -0.38 0.96 62.50 1.06 1732 253 76 16 TRUE 0.32
non-small cell lung cancer KRAS_G12D TP63 41 31 50-65yrs -1.31 -4.03 0.61 1307.97 1.00 1239 40 30 1 FALSE 0.53
non-small cell lung cancer KRAS_G12D TP63 100 38 >65yrs -1.87 -5.13 0.20 1040.15 1.00 1984 100 38 0 FALSE 0.71
non-small cell lung cancer KRAS_G12D TP63 141 69 Age:overall -1.55 -4.49 0.48 1330.20 1.00 3223 140 68 1 FALSE 0.61
colorectal cancer KRAS_G12D JUN 55 11 40-50yrs -0.28 -1.35 0.65 672.71 1.00 373 53 9 2 FALSE 0.24
colorectal cancer KRAS_G12D JUN 122 18 50-65yrs -0.31 -1.38 0.56 663.89 1.00 802 120 16 2 FALSE 0.28
colorectal cancer KRAS_G12D JUN 81 19 >65yrs -0.33 -1.52 0.56 664.06 1.00 536 80 18 1 FALSE 0.28
colorectal cancer KRAS_G12D JUN 258 48 Age:overall -0.31 -1.40 0.55 646.60 1.00 1711 253 43 5 FALSE 0.27
colorectal cancer KRAS_G12D DNMT3B 34 12 <40yrs -5.77 -12.75 -1.60 464.53 1.01 169 34 12 0 FALSE 1.31
colorectal cancer KRAS_G12D DNMT3B 122 28 50-65yrs -5.79 -12.63 -1.70 456.99 1.01 790 122 28 0 FALSE 1.33
colorectal cancer KRAS_G12D DNMT3B 81 15 >65yrs -5.79 -12.90 -1.63 449.85 1.01 538 81 15 0 FALSE 1.32
colorectal cancer KRAS_G12D DNMT3B 237 55 Age:overall -5.77 -12.56 -1.67 452.84 1.01 1497 237 55 0 FALSE 1.33
non-small cell lung cancer KRAS_G12D MYOD1 41 21 50-65yrs -0.72 -3.99 1.05 1118.79 1.00 1251 41 21 0 FALSE 0.22
non-small cell lung cancer KRAS_G12D MYOD1 100 31 >65yrs -0.23 -2.17 1.13 1146.05 1.00 1992 98 29 2 FALSE 0.11
non-small cell lung cancer KRAS_G12D MYOD1 141 52 Age:overall -0.47 -3.07 1.24 1193.39 1.00 3243 139 50 2 FALSE 0.17
colorectal cancer KRAS_G12D FGFR1 63 12 40-50yrs -0.35 -1.39 0.65 72.40 1.05 411 62 11 1 TRUE 0.28
colorectal cancer KRAS_G12D FGFR1 147 21 50-65yrs -0.30 -1.26 0.65 57.09 1.06 913 143 17 4 TRUE 0.25
colorectal cancer KRAS_G12D FGFR1 95 11 >65yrs -0.39 -1.47 0.60 94.43 1.04 616 95 11 0 TRUE 0.32
colorectal cancer KRAS_G12D FGFR1 305 44 Age:overall -0.35 -1.37 0.62 72.61 1.05 1940 300 39 5 TRUE 0.29
colorectal cancer KRAS_G12D MITF 127 25 50-65yrs -0.14 -1.20 0.83 1158.56 1.00 819 124 22 3 FALSE 0.10
colorectal cancer KRAS_G12D MITF 84 14 >65yrs -0.12 -1.20 0.90 1112.66 1.00 553 82 12 2 FALSE 0.08
colorectal cancer KRAS_G12D MITF 211 39 Age:overall -0.13 -1.27 0.94 1313.28 1.00 1372 206 34 5 FALSE 0.08
non-small cell lung cancer KRAS_G12D BTK 41 28 50-65yrs -1.62 -4.87 0.58 1235.87 1.01 1246 41 28 0 TRUE 0.61
non-small cell lung cancer KRAS_G12D BTK 100 29 >65yrs -1.25 -4.17 0.72 1279.39 1.01 2001 99 28 1 TRUE 0.51
non-small cell lung cancer KRAS_G12D BTK 141 57 Age:overall -1.39 -4.49 0.79 1138.02 1.01 3247 140 56 1 TRUE 0.54
colorectal cancer KRAS_G12D SH2B3 115 25 50-65yrs -0.29 -1.40 0.59 921.51 1.00 747 113 23 2 FALSE 0.24
colorectal cancer KRAS_G12D SH2B3 74 19 >65yrs -0.19 -1.20 0.76 827.91 1.00 505 71 16 3 FALSE 0.15
colorectal cancer KRAS_G12D SH2B3 189 44 Age:overall -0.24 -1.33 0.72 827.32 1.00 1252 184 39 5 FALSE 0.18
colorectal cancer KRAS_G12D GLI1 54 17 40-50yrs -0.33 -1.25 0.46 429.62 1.01 347 52 15 2 FALSE 0.36
colorectal cancer KRAS_G12D GLI1 116 36 50-65yrs -0.29 -1.18 0.49 491.58 1.01 738 110 30 6 FALSE 0.32
colorectal cancer KRAS_G12D GLI1 74 25 >65yrs -0.40 -1.38 0.38 353.34 1.01 497 74 25 0 FALSE 0.42
non-small cell lung cancer KRAS_G12D GLI1 41 35 50-65yrs -0.54 -2.12 0.74 1179.74 1.00 1087 40 34 1 FALSE 0.33
non-small cell lung cancer KRAS_G12D GLI1 89 64 >65yrs -0.56 -2.04 0.62 895.38 1.00 1816 87 62 2 FALSE 0.39
colorectal cancer KRAS_G12D GLI1 244 78 Age:overall -0.34 -1.21 0.40 419.52 1.01 1582 236 70 8 FALSE 0.39
non-small cell lung cancer KRAS_G12D GLI1 130 99 Age:overall -0.53 -2.08 0.80 1132.80 1.00 2903 127 96 3 FALSE 0.32
colorectal cancer KRAS_G12D ZFHX3 34 28 <40yrs -0.11 -0.73 0.45 1411.32 1.00 151 30 24 4 FALSE 0.14
colorectal cancer KRAS_G12D ZFHX3 53 32 40-50yrs -0.19 -0.81 0.37 1369.37 1.00 337 50 29 3 FALSE 0.29
colorectal cancer KRAS_G12D ZFHX3 116 82 50-65yrs -0.03 -0.50 0.48 1464.64 1.00 720 103 69 13 FALSE 0.04
colorectal cancer KRAS_G12D ZFHX3 76 84 >65yrs -0.21 -0.77 0.27 1177.48 1.00 469 69 77 7 FALSE 0.37
non-small cell lung cancer KRAS_G12D ZFHX3 41 57 50-65yrs -0.87 -4.00 0.44 1033.70 1.00 1064 41 57 0 FALSE 0.33
non-small cell lung cancer KRAS_G12D ZFHX3 89 96 >65yrs -0.25 -1.30 0.65 1174.30 1.00 1786 84 91 5 FALSE 0.21
uterine cancer KRAS_G12D ZFHX3 10 21 40-50yrs 0.54 -0.30 1.49 1290.69 1.00 63 6 17 4 FALSE 0.61
uterine cancer KRAS_G12D ZFHX3 26 96 50-65yrs 0.37 -0.37 1.05 1423.52 1.00 371 19 89 7 FALSE 0.51
uterine cancer KRAS_G12D ZFHX3 17 90 >65yrs 0.21 -0.66 0.96 1341.00 1.00 361 14 87 3 FALSE 0.22
colorectal cancer KRAS_G12D ZFHX3 279 226 Age:overall -0.14 -0.66 0.34 1551.58 1.00 1677 252 199 27 FALSE 0.23
non-small cell lung cancer KRAS_G12D ZFHX3 130 153 Age:overall -0.59 -2.88 0.61 1193.90 1.01 2850 125 148 5 FALSE 0.29
uterine cancer KRAS_G12D ZFHX3 53 207 Age:overall 0.38 -0.41 1.16 1482.69 1.00 795 39 193 14 FALSE 0.47
colorectal cancer KRAS_G12D MST1R 110 26 50-65yrs -1.71 -3.58 -0.32 1241.89 1.00 720 109 25 1 FALSE 1.35
colorectal cancer KRAS_G12D MST1R 71 33 >65yrs -1.71 -3.56 -0.30 1319.16 1.00 483 70 32 1 FALSE 1.37
colorectal cancer KRAS_G12D MST1R 181 59 Age:overall -1.66 -3.70 0.05 1255.70 1.00 1203 179 57 2 FALSE 1.11
colorectal cancer KRAS_G12D MGA 33 18 <40yrs -0.69 -1.68 0.03 231.72 1.02 156 33 18 0 FALSE 0.88
colorectal cancer KRAS_G12D MGA 53 19 40-50yrs -0.54 -1.37 0.19 305.62 1.01 347 50 16 3 FALSE 0.73
colorectal cancer KRAS_G12D MGA 115 41 50-65yrs -0.55 -1.32 0.13 275.66 1.01 731 110 36 5 FALSE 0.86
colorectal cancer KRAS_G12D MGA 74 45 >65yrs -0.66 -1.51 -0.01 157.50 1.02 481 72 43 2 FALSE 1.00
non-small cell lung cancer KRAS_G12D MGA 41 60 50-65yrs -1.17 -3.24 0.53 739.70 1.01 1064 39 58 2 FALSE 0.68
non-small cell lung cancer KRAS_G12D MGA 89 129 >65yrs -2.23 -5.27 -0.48 1196.88 1.00 1763 89 129 0 FALSE 1.02
uterine cancer KRAS_G12D MGA 12 15 40-50yrs 0.88 -0.61 2.36 1327.36 1.00 67 7 10 5 FALSE 0.62
uterine cancer KRAS_G12D MGA 24 48 50-65yrs -1.83 -5.81 0.14 1155.10 1.00 398 24 48 0 FALSE 0.61
uterine cancer KRAS_G12D MGA 17 47 >65yrs -1.71 -5.68 0.33 1422.14 1.00 388 17 47 0 FALSE 0.57
colorectal cancer KRAS_G12D MGA 275 123 Age:overall -0.61 -1.45 0.02 185.46 1.02 1715 265 113 10 FALSE 0.97
non-small cell lung cancer KRAS_G12D MGA 130 189 Age:overall -1.60 -3.81 0.24 1167.20 1.00 2827 128 187 2 FALSE 0.85
uterine cancer KRAS_G12D MGA 53 110 Age:overall -0.84 -3.42 0.99 1529.33 1.00 853 48 105 5 FALSE 0.35
colorectal cancer KRAS_G12D TCF3 51 12 40-50yrs -0.69 -1.69 0.25 8.58 1.14 338 50 11 1 FALSE 0.61
colorectal cancer KRAS_G12D TCF3 111 26 50-65yrs -0.68 -1.67 0.24 8.19 1.15 720 109 24 2 FALSE 0.62
colorectal cancer KRAS_G12D TCF3 71 22 >65yrs -0.68 -1.68 0.30 8.46 1.15 488 69 20 2 FALSE 0.59
colorectal cancer KRAS_G12D TCF3 233 60 Age:overall -0.69 -1.69 0.25 8.03 1.15 1546 228 55 5 FALSE 0.62
colorectal cancer KRAS_G12D KMT2B 25 25 <40yrs -0.50 -1.40 0.34 1321.11 1.00 75 21 21 4 FALSE 0.57
colorectal cancer KRAS_G12D KMT2B 31 17 40-50yrs -0.75 -1.91 0.17 1414.04 1.00 204 30 16 1 FALSE 0.80
colorectal cancer KRAS_G12D KMT2B 69 59 50-65yrs -0.74 -1.57 0.02 1594.87 1.00 395 65 55 4 FALSE 1.17
colorectal cancer KRAS_G12D KMT2B 46 81 >65yrs -0.55 -1.27 0.19 1449.20 1.00 253 39 74 7 FALSE 0.87
non-small cell lung cancer KRAS_G12D KMT2B 25 22 50-65yrs -1.71 -4.47 0.28 1067.21 1.00 618 25 22 0 FALSE 0.75
non-small cell lung cancer KRAS_G12D KMT2B 51 47 >65yrs -1.57 -4.21 0.26 1145.86 1.00 1033 50 46 1 FALSE 0.76
colorectal cancer KRAS_G12D KMT2B 171 182 Age:overall -0.63 -1.48 0.09 1508.19 1.00 927 155 166 16 FALSE 0.93
non-small cell lung cancer KRAS_G12D KMT2B 76 69 Age:overall -1.65 -4.45 0.28 1155.08 1.00 1651 75 68 1 FALSE 0.75
colorectal cancer KRAS_G12D TCF7L2 34 34 <40yrs 0.28 -0.11 0.65 1301.21 1.00 144 26 26 8 FALSE 0.88
colorectal cancer KRAS_G12D TCF7L2 53 56 40-50yrs 0.23 -0.18 0.58 1130.22 1.00 314 47 50 6 FALSE 0.65
colorectal cancer KRAS_G12D TCF7L2 119 121 50-65yrs 0.26 -0.10 0.60 1339.17 1.00 674 99 101 20 FALSE 0.87
colorectal cancer KRAS_G12D TCF7L2 74 88 >65yrs 0.26 -0.11 0.61 1116.79 1.00 451 60 74 14 FALSE 0.85
colorectal cancer KRAS_G12D TCF7L2 280 299 Age:overall 0.26 -0.10 0.57 1262.68 1.00 1583 232 251 48 FALSE 0.89
colorectal cancer KRAS_G12D MSH3 24 12 <40yrs -0.69 -1.85 0.48 237.18 1.02 79 22 10 2 FALSE 0.57
colorectal cancer KRAS_G12D MSH3 70 31 50-65yrs -0.45 -1.40 0.59 123.94 1.03 404 65 26 5 FALSE 0.40
colorectal cancer KRAS_G12D MSH3 43 39 >65yrs -1.36 -3.51 -0.14 1198.69 1.00 268 43 39 0 FALSE 0.97
colorectal cancer KRAS_G12D MSH3 137 82 Age:overall -0.83 -2.07 0.26 432.94 1.01 751 130 75 7 FALSE 0.76
colorectal cancer KRAS_G12D ANKRD11 33 21 <40yrs -0.16 -0.98 0.82 1501.59 1.00 150 28 16 5 FALSE 0.13
colorectal cancer KRAS_G12D ANKRD11 51 14 40-50yrs -0.43 -1.42 0.56 1449.44 1.00 338 49 12 2 FALSE 0.40
colorectal cancer KRAS_G12D ANKRD11 113 61 50-65yrs -0.44 -1.20 0.27 1490.79 1.00 704 107 55 6 FALSE 0.63
colorectal cancer KRAS_G12D ANKRD11 71 50 >65yrs -1.00 -2.58 -0.06 1036.29 1.00 464 71 50 0 FALSE 0.95
non-small cell lung cancer KRAS_G12D ANKRD11 41 21 50-65yrs 0.36 -1.08 1.48 1236.55 1.00 1093 40 20 1 FALSE 0.23
non-small cell lung cancer KRAS_G12D ANKRD11 90 50 >65yrs 0.45 -0.68 1.36 1232.72 1.00 1823 86 46 4 FALSE 0.41
colorectal cancer KRAS_G12D ANKRD11 268 146 Age:overall -0.52 -1.40 0.24 1428.84 1.00 1656 255 133 13 FALSE 0.68
non-small cell lung cancer KRAS_G12D ANKRD11 131 71 Age:overall 0.42 -0.92 1.56 1223.21 1.00 2916 126 66 5 FALSE 0.29
colorectal cancer KRAS_G12D PGR 111 24 50-65yrs 0.08 -1.07 1.17 340.48 1.00 725 106 19 5 FALSE 0.05
colorectal cancer KRAS_G12D PGR 71 24 >65yrs -1.49 -6.02 0.41 284.53 1.01 483 71 24 0 FALSE 0.43
non-small cell lung cancer KRAS_G12D PGR 41 35 50-65yrs -1.07 -3.59 0.44 843.97 1.00 1080 41 35 0 FALSE 0.46
non-small cell lung cancer KRAS_G12D PGR 89 49 >65yrs -0.71 -2.56 0.66 844.80 1.00 1820 87 47 2 FALSE 0.41
colorectal cancer KRAS_G12D PGR 182 48 Age:overall -0.66 -3.69 1.15 875.77 1.01 1208 177 43 5 FALSE 0.24
non-small cell lung cancer KRAS_G12D PGR 130 84 Age:overall -0.87 -3.06 0.67 987.81 1.00 2900 128 82 2 FALSE 0.44
colorectal cancer KRAS_G12D PLCG2 51 14 40-50yrs -0.04 -0.92 0.86 1209.87 1.00 338 48 11 3 FALSE 0.03
colorectal cancer KRAS_G12D PLCG2 111 27 50-65yrs -0.21 -1.14 0.56 1052.38 1.00 720 109 25 2 FALSE 0.21
colorectal cancer KRAS_G12D PLCG2 71 35 >65yrs -0.10 -0.96 0.66 1272.91 1.00 478 67 31 4 FALSE 0.09
non-small cell lung cancer KRAS_G12D PLCG2 41 13 50-65yrs -4.80 -12.22 -0.35 403.32 1.01 1101 41 13 0 FALSE 0.90
non-small cell lung cancer KRAS_G12D PLCG2 89 43 >65yrs -4.82 -11.91 -0.72 325.56 1.01 1828 89 43 0 FALSE 0.99
colorectal cancer KRAS_G12D PLCG2 233 76 Age:overall -0.11 -0.97 0.66 1314.86 1.00 1536 224 67 9 FALSE 0.10
non-small cell lung cancer KRAS_G12D PLCG2 130 56 Age:overall -4.70 -11.58 -0.44 459.27 1.01 2929 130 56 0 FALSE 0.96
colorectal cancer KRAS_G12D POLD1 34 12 <40yrs -0.51 -1.45 0.39 905.75 1.00 161 31 9 3 TRUE 0.57
colorectal cancer KRAS_G12D POLD1 53 16 40-50yrs -0.72 -1.63 0.08 1136.95 1.00 346 53 16 0 TRUE 0.99
colorectal cancer KRAS_G12D POLD1 115 39 50-65yrs -0.68 -1.52 0.08 1394.42 1.00 737 113 37 2 TRUE 1.01
colorectal cancer KRAS_G12D POLD1 76 45 >65yrs -0.59 -1.48 0.15 953.46 1.00 489 72 41 4 TRUE 0.83
non-small cell lung cancer KRAS_G12D POLD1 41 23 50-65yrs 0.57 -0.96 2.03 476.19 1.01 1099 38 20 3 TRUE 0.34
non-small cell lung cancer KRAS_G12D POLD1 89 32 >65yrs -0.72 -4.95 0.98 904.09 1.00 1841 89 32 0 TRUE 0.19
colorectal cancer KRAS_G12D POLD1 278 112 Age:overall -0.63 -1.44 0.10 989.70 1.00 1733 269 103 9 TRUE 0.95
non-small cell lung cancer KRAS_G12D POLD1 130 55 Age:overall -0.03 -2.56 1.77 1281.17 1.00 2940 127 52 3 TRUE 0.01
colorectal cancer KRAS_G12D INHBA 115 26 50-65yrs 0.42 -0.43 1.24 780.57 1.00 748 109 20 6 FALSE 0.50
colorectal cancer KRAS_G12D INHBA 74 19 >65yrs 0.28 -0.78 1.14 1107.51 1.00 503 72 17 2 FALSE 0.25
non-small cell lung cancer KRAS_G12D INHBA 41 29 50-65yrs -1.90 -4.96 0.10 965.23 1.00 1090 41 29 0 FALSE 0.83
non-small cell lung cancer KRAS_G12D INHBA 89 55 >65yrs -1.74 -4.34 0.10 569.72 1.01 1825 88 54 1 FALSE 0.87
colorectal cancer KRAS_G12D INHBA 189 45 Age:overall 0.35 -0.63 1.31 1253.51 1.00 1251 181 37 8 FALSE 0.32
non-small cell lung cancer KRAS_G12D INHBA 130 84 Age:overall -1.81 -4.70 0.18 905.29 1.00 2915 129 83 1 FALSE 0.85
colorectal cancer KRAS_G12D PREX2 31 21 40-50yrs -0.16 -0.96 0.57 372.99 1.01 205 29 19 2 FALSE 0.16
colorectal cancer KRAS_G12D PREX2 70 34 50-65yrs -0.12 -0.89 0.55 338.09 1.01 404 64 28 6 FALSE 0.13
colorectal cancer KRAS_G12D PREX2 43 29 >65yrs -0.19 -0.99 0.50 393.68 1.01 277 41 27 2 FALSE 0.20
non-small cell lung cancer KRAS_G12D PREX2 25 41 50-65yrs -0.50 -1.91 0.78 1110.25 1.00 602 23 39 2 FALSE 0.33
non-small cell lung cancer KRAS_G12D PREX2 51 63 >65yrs -0.70 -2.11 0.43 1033.65 1.01 1022 50 62 1 FALSE 0.53
colorectal cancer KRAS_G12D PREX2 144 84 Age:overall -0.16 -0.93 0.52 339.43 1.01 886 134 74 10 FALSE 0.17
non-small cell lung cancer KRAS_G12D PREX2 76 104 Age:overall -0.59 -2.12 0.68 1134.04 1.01 1624 73 101 3 FALSE 0.36
colorectal cancer KRAS_G12D AMER1 35 13 <40yrs 0.10 -0.62 0.78 1283.73 1.00 174 33 11 2 FALSE 0.11
colorectal cancer KRAS_G12D AMER1 56 33 40-50yrs 0.13 -0.48 0.73 1394.21 1.00 368 51 28 5 FALSE 0.17
colorectal cancer KRAS_G12D AMER1 127 53 50-65yrs 0.02 -0.59 0.55 1331.60 1.00 796 121 47 6 FALSE 0.02
colorectal cancer KRAS_G12D AMER1 84 70 >65yrs 0.22 -0.31 0.77 1305.44 1.00 513 72 58 12 FALSE 0.37
non-small cell lung cancer KRAS_G12D AMER1 41 48 50-65yrs -0.20 -1.63 0.89 1334.30 1.00 1231 40 47 1 FALSE 0.12
non-small cell lung cancer KRAS_G12D AMER1 100 93 >65yrs -0.02 -1.12 0.86 1070.15 1.00 1955 95 88 5 FALSE 0.01
uterine cancer KRAS_G12D AMER1 25 33 50-65yrs -1.28 -4.06 0.67 945.20 1.00 466 24 32 1 FALSE 0.55
uterine cancer KRAS_G12D AMER1 18 18 >65yrs -1.62 -4.97 0.53 1107.18 1.00 444 18 18 0 FALSE 0.58
colorectal cancer KRAS_G12D AMER1 302 169 Age:overall 0.12 -0.44 0.63 1287.83 1.00 1851 277 144 25 FALSE 0.18
non-small cell lung cancer KRAS_G12D AMER1 141 141 Age:overall -0.12 -1.40 0.99 1259.61 1.00 3186 135 135 6 FALSE 0.07
uterine cancer KRAS_G12D AMER1 43 51 Age:overall -1.41 -4.33 0.72 1055.73 1.00 910 42 50 1 FALSE 0.56
colorectal cancer KRAS_G12D HLA-A 110 17 50-65yrs -0.61 -2.18 0.62 1283.32 1.00 730 108 15 2 FALSE 0.42
colorectal cancer KRAS_G12D HLA-A 71 20 >65yrs -0.78 -2.41 0.41 1338.70 1.00 489 70 19 1 FALSE 0.55
colorectal cancer KRAS_G12D HLA-A 181 37 Age:overall -0.69 -2.30 0.63 1346.85 1.00 1219 178 34 3 FALSE 0.44
colorectal cancer KRAS_G12D EPHA7 53 13 40-50yrs -0.28 -1.24 0.43 152.01 1.02 347 53 13 0 FALSE 0.28
colorectal cancer KRAS_G12D EPHA7 115 39 50-65yrs -0.19 -1.00 0.45 104.04 1.03 739 109 33 6 FALSE 0.21
colorectal cancer KRAS_G12D EPHA7 74 30 >65yrs -0.23 -1.07 0.44 110.49 1.03 496 71 27 3 FALSE 0.26
non-small cell lung cancer KRAS_G12D EPHA7 42 48 50-65yrs -0.01 -1.11 1.06 1250.77 1.00 1077 39 45 3 FALSE 0.00
non-small cell lung cancer KRAS_G12D EPHA7 89 77 >65yrs -0.24 -1.38 0.68 1318.67 1.00 1800 87 75 2 FALSE 0.18
colorectal cancer KRAS_G12D EPHA7 242 82 Age:overall -0.24 -1.07 0.42 112.38 1.03 1582 233 73 9 FALSE 0.26
non-small cell lung cancer KRAS_G12D EPHA7 131 125 Age:overall -0.12 -1.30 0.97 1430.92 1.00 2877 126 120 5 FALSE 0.08
colorectal cancer KRAS_G12D NCOA3 115 19 50-65yrs -0.80 -2.29 0.44 171.37 1.02 752 113 17 2 TRUE 0.54
colorectal cancer KRAS_G12D NCOA3 74 23 >65yrs -0.97 -2.51 0.25 235.17 1.02 499 73 22 1 TRUE 0.70
colorectal cancer KRAS_G12D NCOA3 189 42 Age:overall -0.88 -2.55 0.50 246.81 1.02 1251 186 39 3 TRUE 0.55
non-small cell lung cancer KRAS_G12D DROSHA 25 17 50-65yrs -5.04 -10.51 -0.73 943.17 1.00 615 25 17 0 FALSE 1.58
non-small cell lung cancer KRAS_G12D DROSHA 51 34 >65yrs -5.01 -10.44 -0.84 852.17 1.00 1036 51 34 0 FALSE 1.63
non-small cell lung cancer KRAS_G12D DROSHA 76 51 Age:overall -4.99 -10.32 -0.82 813.21 1.00 1651 76 51 0 FALSE 1.64
colorectal cancer KRAS_G12D SLX4 64 16 50-65yrs -0.32 -1.74 1.05 391.40 1.00 392 61 13 3 FALSE 0.17
colorectal cancer KRAS_G12D SLX4 40 18 >65yrs -1.37 -5.33 0.42 1279.09 1.00 274 40 18 0 FALSE 0.46
colorectal cancer KRAS_G12D SLX4 104 34 Age:overall -0.82 -3.44 0.98 797.39 1.00 666 101 31 3 FALSE 0.35
colorectal cancer KRAS_G12D INPPL1 29 12 40-50yrs -1.26 -2.93 0.01 93.83 1.01 195 28 11 1 FALSE 1.11
colorectal cancer KRAS_G12D INPPL1 64 29 50-65yrs -1.30 -2.87 -0.01 88.04 1.01 383 63 28 1 FALSE 1.22
colorectal cancer KRAS_G12D INPPL1 40 25 >65yrs -1.29 -2.91 0.01 91.54 1.01 273 39 24 1 FALSE 1.15
colorectal cancer KRAS_G12D INPPL1 133 66 Age:overall -1.28 -2.91 0.00 95.48 1.01 851 130 63 3 FALSE 1.16
colorectal cancer KRAS_G12V SPEN 13 23 <40yrs -2.37 -4.29 -0.82 1430.64 1.00 190 13 23 0 FALSE 2.16
colorectal cancer KRAS_G12V SPEN 42 25 40-50yrs -2.40 -4.22 -0.94 1478.47 1.00 388 42 25 0 FALSE 2.28
colorectal cancer KRAS_G12V SPEN 90 45 50-65yrs -2.30 -4.05 -0.87 1459.35 1.00 843 89 44 1 FALSE 2.28
colorectal cancer KRAS_G12V SPEN 59 62 >65yrs -2.31 -4.05 -0.98 1387.95 1.00 547 58 61 1 FALSE 2.31
non-small cell lung cancer KRAS_G12V SPEN 62 67 50-65yrs -0.38 -1.67 0.63 1634.79 1.00 1212 60 65 2 FALSE 0.27
non-small cell lung cancer KRAS_G12V SPEN 100 49 >65yrs -0.04 -1.29 1.02 1417.46 1.00 1990 97 46 3 FALSE 0.03
uterine cancer KRAS_G12V SPEN 7 19 40-50yrs -0.93 -2.68 0.56 1443.14 1.00 73 6 18 1 FALSE 0.61
uterine cancer KRAS_G12V SPEN 34 54 50-65yrs -1.13 -2.83 0.13 1400.64 1.00 448 33 53 1 FALSE 0.89
uterine cancer KRAS_G12V SPEN 17 44 >65yrs -0.98 -2.62 0.41 1479.29 1.00 428 16 43 1 FALSE 0.70
colorectal cancer KRAS_G12V SPEN 204 155 Age:overall -2.35 -4.01 -0.98 1449.18 1.00 1968 202 153 2 FALSE 2.46
non-small cell lung cancer KRAS_G12V SPEN 162 116 Age:overall -0.23 -1.72 1.17 1423.70 1.00 3202 157 111 5 FALSE 0.12
uterine cancer KRAS_G12V SPEN 58 117 Age:overall -1.00 -2.60 0.34 1471.94 1.00 949 55 114 3 FALSE 0.73
colorectal cancer KRAS_G12V KMT2C 12 25 <40yrs -1.27 -2.34 -0.37 1225.50 1.00 183 12 25 0 FALSE 1.92
colorectal cancer KRAS_G12V KMT2C 42 39 40-50yrs -1.15 -2.15 -0.28 1046.41 1.00 373 39 36 3 FALSE 1.83
colorectal cancer KRAS_G12V KMT2C 86 65 50-65yrs -1.31 -2.35 -0.50 1013.38 1.00 804 85 64 1 FALSE 2.29
colorectal cancer KRAS_G12V KMT2C 55 69 >65yrs -1.23 -2.19 -0.44 1264.38 1.00 528 53 67 2 FALSE 2.12
non-small cell lung cancer KRAS_G12V KMT2C 63 90 50-65yrs 0.53 -0.14 1.21 1048.44 1.00 1176 54 81 9 FALSE 0.92
non-small cell lung cancer KRAS_G12V KMT2C 100 122 >65yrs 0.31 -0.38 0.91 1441.37 1.00 1911 94 116 6 FALSE 0.46
uterine cancer KRAS_G12V KMT2C 7 20 40-50yrs -0.60 -2.00 0.58 1419.04 1.00 64 6 19 1 FALSE 0.44
uterine cancer KRAS_G12V KMT2C 32 68 50-65yrs -0.58 -1.73 0.38 1278.30 1.00 421 29 65 3 FALSE 0.55
uterine cancer KRAS_G12V KMT2C 17 55 >65yrs -0.68 -2.05 0.41 1401.07 1.00 395 16 54 1 FALSE 0.57
colorectal cancer KRAS_G12V KMT2C 195 198 Age:overall -1.24 -2.23 -0.43 1046.08 1.00 1888 189 192 6 FALSE 2.20
non-small cell lung cancer KRAS_G12V KMT2C 163 212 Age:overall 0.42 -0.36 1.20 1456.25 1.00 3087 148 197 15 FALSE 0.50
uterine cancer KRAS_G12V KMT2C 56 143 Age:overall -0.62 -1.86 0.51 1320.57 1.00 880 51 138 5 FALSE 0.52
cancer of unknown primary KRAS_G12V TP53 27 154 50-65yrs 0.16 -0.56 0.86 1543.04 1.00 162 14 141 13 TRUE 0.18
cancer of unknown primary KRAS_G12V TP53 23 218 >65yrs 0.12 -0.66 0.88 1244.09 1.00 159 10 205 13 TRUE 0.12
colorectal cancer KRAS_G12V TP53 13 165 <40yrs -0.80 -1.21 -0.42 1522.65 1.00 76 6 158 7 TRUE 4.49
colorectal cancer KRAS_G12V TP53 45 350 40-50yrs -0.76 -1.12 -0.41 1379.83 1.00 130 22 327 23 TRUE 4.90
colorectal cancer KRAS_G12V TP53 109 724 50-65yrs -0.76 -1.07 -0.44 1282.16 1.00 339 58 673 51 TRUE 5.94
colorectal cancer KRAS_G12V TP53 65 480 >65yrs -0.77 -1.10 -0.42 1367.36 1.00 255 34 449 31 TRUE 5.40
non-small cell lung cancer KRAS_G12V TP53 6 102 40-50yrs -0.78 -1.50 -0.21 1346.93 1.00 98 5 101 1 TRUE 1.82
non-small cell lung cancer KRAS_G12V TP53 64 814 50-65yrs -0.59 -0.99 -0.19 1471.73 1.00 584 35 785 29 TRUE 2.46
non-small cell lung cancer KRAS_G12V TP53 107 1113 >65yrs -0.69 -1.06 -0.34 1397.94 1.00 1079 72 1078 35 TRUE 3.80
pancreatic cancer KRAS_G12V TP53 19 60 40-50yrs 0.55 -0.03 1.15 1140.71 1.00 59 7 48 12 TRUE 1.26
pancreatic cancer KRAS_G12V TP53 162 384 50-65yrs 0.77 0.43 1.13 1435.19 1.00 212 42 264 120 TRUE 4.66
pancreatic cancer KRAS_G12V TP53 220 495 >65yrs 0.62 0.29 0.93 1238.86 1.00 227 63 338 157 TRUE 3.81
uterine cancer KRAS_G12V TP53 8 28 40-50yrs -1.66 -3.40 -0.47 1507.50 1.00 60 8 28 0 TRUE 1.59
uterine cancer KRAS_G12V TP53 40 226 50-65yrs -1.18 -1.95 -0.44 1438.70 1.00 339 32 218 8 TRUE 2.67
uterine cancer KRAS_G12V TP53 19 285 >65yrs -1.49 -2.45 -0.63 1448.27 1.00 247 15 281 4 TRUE 2.92
cancer of unknown primary KRAS_G12V TP53 52 420 Age:overall 0.17 -0.90 1.33 1626.91 1.00 416 24 392 28 TRUE 0.12
colorectal cancer KRAS_G12V TP53 232 1719 Age:overall -0.77 -1.09 -0.45 1276.99 1.00 800 120 1607 112 TRUE 5.86
non-small cell lung cancer KRAS_G12V TP53 178 2056 Age:overall -0.70 -1.19 -0.26 1338.81 1.00 1798 113 1991 65 TRUE 2.48
pancreatic cancer KRAS_G12V TP53 401 939 Age:overall 0.64 0.12 1.14 1622.87 1.00 498 112 650 289 TRUE 1.89
uterine cancer KRAS_G12V TP53 67 539 Age:overall -1.43 -2.60 -0.48 1554.86 1.00 646 55 527 12 TRUE 2.05
colorectal cancer KRAS_G12V ATRX 42 31 40-50yrs -0.62 -1.82 0.54 1455.50 1.00 388 39 28 3 TRUE 0.52
colorectal cancer KRAS_G12V ATRX 90 31 50-65yrs -0.81 -1.98 0.31 1322.47 1.00 850 88 29 2 TRUE 0.78
colorectal cancer KRAS_G12V ATRX 59 48 >65yrs -1.25 -2.94 -0.13 1525.65 1.00 551 59 48 0 TRUE 1.06
non-small cell lung cancer KRAS_G12V ATRX 63 74 50-65yrs 0.16 -0.57 0.82 932.42 1.00 1193 58 69 5 TRUE 0.18
non-small cell lung cancer KRAS_G12V ATRX 100 123 >65yrs 0.12 -0.61 0.78 904.35 1.00 1929 94 117 6 TRUE 0.13
uterine cancer KRAS_G12V ATRX 7 26 40-50yrs -2.98 -6.29 -0.72 1152.60 1.00 69 7 26 0 TRUE 1.48
uterine cancer KRAS_G12V ATRX 34 96 50-65yrs -3.22 -6.22 -1.19 1512.27 1.00 425 34 96 0 TRUE 1.90
uterine cancer KRAS_G12V ATRX 17 43 >65yrs -2.37 -5.21 -0.11 1322.16 1.00 434 16 42 1 TRUE 1.13
colorectal cancer KRAS_G12V ATRX 191 110 Age:overall -0.89 -2.12 0.21 1420.61 1.00 1789 186 105 5 TRUE 0.88
non-small cell lung cancer KRAS_G12V ATRX 163 197 Age:overall 0.14 -0.61 0.84 908.66 1.00 3122 152 186 11 TRUE 0.14
uterine cancer KRAS_G12V ATRX 58 176 Age:overall -2.83 -5.52 -0.80 1383.81 1.00 956 57 175 1 TRUE 1.69
colorectal cancer KRAS_G12V ATR 13 17 <40yrs -1.41 -2.95 -0.28 444.46 1.01 193 12 16 1 FALSE 1.47
colorectal cancer KRAS_G12V ATR 42 22 40-50yrs -1.45 -3.03 -0.32 357.71 1.01 396 42 22 0 FALSE 1.58
colorectal cancer KRAS_G12V ATR 90 48 50-65yrs -1.41 -2.88 -0.34 395.09 1.01 844 88 46 2 FALSE 1.58
colorectal cancer KRAS_G12V ATR 59 27 >65yrs -1.46 -2.99 -0.40 428.66 1.01 566 59 27 0 FALSE 1.61
non-small cell lung cancer KRAS_G12V ATR 62 50 50-65yrs -1.35 -3.06 -0.04 859.49 1.00 1207 61 49 1 FALSE 1.13
non-small cell lung cancer KRAS_G12V ATR 100 73 >65yrs -1.38 -3.08 -0.07 949.97 1.00 1957 99 72 1 FALSE 1.16
uterine cancer KRAS_G12V ATR 34 55 50-65yrs -5.40 -12.38 -1.17 1307.75 1.00 445 34 55 0 FALSE 1.20
uterine cancer KRAS_G12V ATR 17 25 >65yrs -5.27 -12.25 -0.87 1315.91 1.00 439 17 25 0 FALSE 1.11
colorectal cancer KRAS_G12V ATR 204 114 Age:overall -1.43 -2.90 -0.38 376.36 1.01 1999 201 111 3 FALSE 1.64
non-small cell lung cancer KRAS_G12V ATR 162 123 Age:overall -1.37 -3.08 -0.05 922.33 1.00 3164 160 121 2 FALSE 1.12
uterine cancer KRAS_G12V ATR 51 80 Age:overall -5.16 -11.83 -0.84 1336.45 1.00 884 51 80 0 FALSE 1.16
colorectal cancer KRAS_G12V PDGFRA 13 12 <40yrs -0.39 -2.07 0.88 1254.22 1.00 214 13 12 0 TRUE 0.22
colorectal cancer KRAS_G12V PDGFRA 45 14 40-50yrs 0.26 -1.11 1.60 896.05 1.00 429 41 10 4 TRUE 0.15
colorectal cancer KRAS_G12V PDGFRA 106 22 50-65yrs -0.57 -2.22 0.61 1232.32 1.00 948 106 22 0 TRUE 0.37
colorectal cancer KRAS_G12V PDGFRA 62 12 >65yrs -0.25 -1.68 0.87 1170.78 1.00 648 61 11 1 TRUE 0.16
non-small cell lung cancer KRAS_G12V PDGFRA 63 57 50-65yrs -0.71 -2.28 0.66 683.24 1.00 1260 60 54 3 TRUE 0.48
non-small cell lung cancer KRAS_G12V PDGFRA 106 86 >65yrs -1.54 -4.87 -0.06 805.20 1.01 1996 106 86 0 TRUE 0.65
colorectal cancer KRAS_G12V PDGFRA 226 60 Age:overall -0.24 -1.52 0.82 1131.48 1.00 2239 221 55 5 TRUE 0.17
non-small cell lung cancer KRAS_G12V PDGFRA 169 143 Age:overall -1.13 -3.47 0.40 1033.81 1.00 3256 166 140 3 TRUE 0.60
colorectal cancer KRAS_G12V FBXW7 13 28 <40yrs -0.52 -1.00 -0.03 259.40 1.02 199 11 26 2 TRUE 1.51
colorectal cancer KRAS_G12V FBXW7 46 60 40-50yrs -0.53 -1.01 -0.07 206.56 1.02 389 43 57 3 TRUE 1.67
colorectal cancer KRAS_G12V FBXW7 106 144 50-65yrs -0.53 -0.99 -0.09 142.63 1.02 850 98 136 8 TRUE 1.80
colorectal cancer KRAS_G12V FBXW7 63 107 >65yrs -0.51 -0.98 -0.04 156.52 1.01 574 56 100 7 TRUE 1.59
non-small cell lung cancer KRAS_G12V FBXW7 63 32 50-65yrs -0.11 -1.39 0.95 873.02 1.00 1282 61 30 2 TRUE 0.07
non-small cell lung cancer KRAS_G12V FBXW7 106 51 >65yrs -0.16 -1.44 0.81 991.56 1.00 2033 104 49 2 TRUE 0.11
uterine cancer KRAS_G12V FBXW7 8 13 40-50yrs -0.79 -2.32 0.41 1238.89 1.00 78 7 12 1 TRUE 0.61
uterine cancer KRAS_G12V FBXW7 39 60 50-65yrs -0.87 -2.18 0.14 1014.75 1.00 488 37 58 2 TRUE 0.83
uterine cancer KRAS_G12V FBXW7 19 70 >65yrs -0.91 -2.27 0.13 928.16 1.00 434 18 69 1 TRUE 0.84
colorectal cancer KRAS_G12V FBXW7 228 339 Age:overall -0.52 -0.97 -0.09 152.69 1.02 2012 208 319 20 TRUE 1.75
non-small cell lung cancer KRAS_G12V FBXW7 169 83 Age:overall -0.14 -1.45 0.90 1007.13 1.00 3315 165 79 4 TRUE 0.08
uterine cancer KRAS_G12V FBXW7 66 143 Age:overall -0.86 -2.23 0.23 992.86 1.00 1000 62 139 4 TRUE 0.79
colorectal cancer KRAS_G12V MAP3K1 42 24 40-50yrs -0.60 -1.59 0.32 638.83 1.01 391 40 22 2 FALSE 0.66
colorectal cancer KRAS_G12V MAP3K1 90 34 50-65yrs -0.64 -1.61 0.26 907.27 1.01 847 88 32 2 FALSE 0.76
colorectal cancer KRAS_G12V MAP3K1 59 25 >65yrs -0.64 -1.65 0.27 948.60 1.01 570 58 24 1 FALSE 0.73
non-small cell lung cancer KRAS_G12V MAP3K1 62 28 50-65yrs -0.88 -3.39 0.65 1270.35 1.00 1226 62 28 0 FALSE 0.38
non-small cell lung cancer KRAS_G12V MAP3K1 101 33 >65yrs -0.53 -2.46 0.86 889.84 1.00 1997 99 31 2 FALSE 0.28
uterine cancer KRAS_G12V MAP3K1 34 31 50-65yrs -5.89 -16.28 -0.94 42.84 1.08 451 34 31 0 FALSE 0.95
uterine cancer KRAS_G12V MAP3K1 17 27 >65yrs -5.87 -16.13 -0.85 43.07 1.08 435 17 27 0 FALSE 0.92
colorectal cancer KRAS_G12V MAP3K1 191 83 Age:overall -0.63 -1.60 0.27 843.80 1.01 1808 186 78 5 FALSE 0.74
non-small cell lung cancer KRAS_G12V MAP3K1 163 61 Age:overall -0.69 -2.78 0.88 1201.27 1.00 3223 161 59 2 FALSE 0.33
uterine cancer KRAS_G12V MAP3K1 51 58 Age:overall -5.77 -16.19 -0.85 40.85 1.09 886 51 58 0 FALSE 0.93
colorectal cancer KRAS_G12V NSD1 13 15 <40yrs -0.80 -2.21 0.48 1165.92 1.00 192 12 14 1 FALSE 0.62
colorectal cancer KRAS_G12V NSD1 42 16 40-50yrs -0.83 -2.23 0.33 1153.83 1.00 397 41 15 1 FALSE 0.69
colorectal cancer KRAS_G12V NSD1 90 22 50-65yrs -1.02 -2.52 0.12 1314.43 1.00 856 90 22 0 FALSE 0.89
colorectal cancer KRAS_G12V NSD1 60 33 >65yrs -0.80 -2.13 0.32 968.32 1.00 565 58 31 2 FALSE 0.68
non-small cell lung cancer KRAS_G12V NSD1 62 31 50-65yrs 0.06 -1.16 1.10 422.07 1.00 1223 61 30 1 FALSE 0.04
non-small cell lung cancer KRAS_G12V NSD1 100 55 >65yrs 0.15 -0.94 1.06 269.23 1.00 1978 96 51 4 FALSE 0.12
uterine cancer KRAS_G12V NSD1 7 26 40-50yrs -0.46 -2.26 1.04 1606.04 1.00 68 6 25 1 FALSE 0.24
uterine cancer KRAS_G12V NSD1 34 52 50-65yrs -0.86 -2.63 0.41 1390.76 1.00 445 33 51 1 FALSE 0.58
uterine cancer KRAS_G12V NSD1 18 37 >65yrs 0.65 -0.62 1.86 1413.26 1.00 432 14 33 4 FALSE 0.52
colorectal cancer KRAS_G12V NSD1 205 86 Age:overall -0.86 -2.14 0.18 946.70 1.00 2010 201 82 4 FALSE 0.80
non-small cell lung cancer KRAS_G12V NSD1 162 86 Age:overall 0.11 -1.03 1.15 348.00 1.00 3201 157 81 5 FALSE 0.08
uterine cancer KRAS_G12V NSD1 59 115 Age:overall -0.20 -1.82 1.14 1607.53 1.00 945 53 109 6 FALSE 0.11
colorectal cancer KRAS_G12V FLT4 43 24 40-50yrs -0.58 -1.73 0.50 1494.78 1.00 390 40 21 3 TRUE 0.51
colorectal cancer KRAS_G12V FLT4 90 42 50-65yrs -1.01 -2.25 -0.01 1470.46 1.00 838 89 41 1 TRUE 1.08
colorectal cancer KRAS_G12V FLT4 59 63 >65yrs -0.95 -2.09 -0.04 1480.01 1.00 540 57 61 2 TRUE 1.16
non-small cell lung cancer KRAS_G12V FLT4 62 43 50-65yrs -0.56 -2.02 0.61 796.87 1.00 1213 60 41 2 TRUE 0.39
non-small cell lung cancer KRAS_G12V FLT4 100 54 >65yrs -0.68 -2.18 0.50 831.36 1.00 1978 99 53 1 TRUE 0.50
uterine cancer KRAS_G12V FLT4 34 21 50-65yrs -1.21 -3.94 0.73 1068.29 1.00 461 33 20 1 TRUE 0.51
uterine cancer KRAS_G12V FLT4 17 20 >65yrs -1.54 -5.29 0.65 1081.58 1.00 441 17 20 0 TRUE 0.51
colorectal cancer KRAS_G12V FLT4 192 129 Age:overall -0.83 -2.01 0.16 1496.68 1.00 1768 186 123 6 TRUE 0.90
non-small cell lung cancer KRAS_G12V FLT4 162 97 Age:overall -0.62 -2.13 0.59 976.68 1.00 3191 159 94 3 TRUE 0.43
uterine cancer KRAS_G12V FLT4 51 41 Age:overall -1.34 -4.37 0.71 1190.93 1.00 902 50 40 1 TRUE 0.50
colorectal cancer KRAS_G12V PTPRD 42 18 40-50yrs -1.73 -3.57 -0.47 211.34 1.01 397 41 17 1 FALSE 1.43
colorectal cancer KRAS_G12V PTPRD 90 43 50-65yrs -1.75 -3.50 -0.52 201.04 1.01 842 89 42 1 FALSE 1.49
colorectal cancer KRAS_G12V PTPRD 59 32 >65yrs -1.76 -3.60 -0.48 213.76 1.01 563 59 32 0 FALSE 1.48
non-small cell lung cancer KRAS_G12V PTPRD 6 13 40-50yrs 0.00 -1.11 0.80 1405.70 1.00 175 6 13 0 FALSE 0.00
non-small cell lung cancer KRAS_G12V PTPRD 64 163 50-65yrs 0.25 -0.34 0.86 1348.25 1.00 1127 52 151 12 FALSE 0.39
non-small cell lung cancer KRAS_G12V PTPRD 100 214 >65yrs -0.04 -0.68 0.50 1451.14 1.00 1852 92 206 8 FALSE 0.05
uterine cancer KRAS_G12V PTPRD 7 11 40-50yrs -1.34 -3.45 0.37 1317.34 1.00 77 7 11 0 FALSE 0.77
uterine cancer KRAS_G12V PTPRD 34 53 50-65yrs -1.29 -3.26 0.12 1042.16 1.00 451 33 52 1 FALSE 0.87
uterine cancer KRAS_G12V PTPRD 17 29 >65yrs -1.12 -3.15 0.48 1143.17 1.00 436 16 28 1 FALSE 0.64
colorectal cancer KRAS_G12V PTPRD 191 93 Age:overall -1.74 -3.48 -0.51 215.81 1.01 1802 189 91 2 FALSE 1.47
non-small cell lung cancer KRAS_G12V PTPRD 170 390 Age:overall 0.06 -0.68 0.69 1481.36 1.00 3154 150 370 20 FALSE 0.07
uterine cancer KRAS_G12V PTPRD 58 93 Age:overall -1.25 -3.21 0.33 1006.96 1.00 964 56 91 2 FALSE 0.78
colorectal cancer KRAS_G12V RET 106 30 50-65yrs -2.05 -4.25 -0.38 323.97 1.01 939 105 29 1 TRUE 1.46
colorectal cancer KRAS_G12V RET 62 20 >65yrs -2.12 -4.62 -0.32 338.45 1.01 640 62 20 0 TRUE 1.30
non-small cell lung cancer KRAS_G12V RET 63 29 50-65yrs 0.36 -0.70 1.38 802.90 1.00 1285 60 26 3 TRUE 0.31
non-small cell lung cancer KRAS_G12V RET 106 61 >65yrs 0.19 -0.81 1.10 934.75 1.00 2021 103 58 3 TRUE 0.16
colorectal cancer KRAS_G12V RET 168 50 Age:overall -2.07 -4.42 -0.32 328.38 1.01 1579 167 49 1 TRUE 1.33
non-small cell lung cancer KRAS_G12V RET 169 90 Age:overall 0.28 -0.78 1.30 1041.83 1.00 3306 163 84 6 TRUE 0.21
colorectal cancer KRAS_G12V KDM5A 42 21 40-50yrs -1.73 -3.34 -0.37 299.79 1.02 396 41 20 1 FALSE 1.64
colorectal cancer KRAS_G12V KDM5A 90 35 50-65yrs -1.74 -3.33 -0.40 303.06 1.02 851 89 34 1 FALSE 1.72
colorectal cancer KRAS_G12V KDM5A 59 30 >65yrs -1.75 -3.36 -0.37 391.57 1.02 562 59 30 0 FALSE 1.70
non-small cell lung cancer KRAS_G12V KDM5A 62 25 50-65yrs 0.26 -0.99 1.22 324.61 1.02 1230 61 24 1 FALSE 0.18
non-small cell lung cancer KRAS_G12V KDM5A 100 45 >65yrs 0.38 -0.62 1.25 275.86 1.01 1990 96 41 4 FALSE 0.38
uterine cancer KRAS_G12V KDM5A 34 31 50-65yrs -5.07 -11.84 -0.82 641.56 1.00 454 34 31 0 FALSE 1.11
uterine cancer KRAS_G12V KDM5A 17 20 >65yrs -5.05 -11.84 -0.63 387.90 1.00 441 17 20 0 FALSE 1.05
colorectal cancer KRAS_G12V KDM5A 191 86 Age:overall -1.74 -3.29 -0.39 317.55 1.02 1809 189 84 2 FALSE 1.72
non-small cell lung cancer KRAS_G12V KDM5A 162 70 Age:overall 0.32 -0.90 1.28 447.70 1.01 3220 157 65 5 FALSE 0.24
uterine cancer KRAS_G12V KDM5A 51 51 Age:overall -4.94 -11.60 -0.79 607.03 1.00 895 51 51 0 FALSE 1.09
colorectal cancer KRAS_G12V PIK3C2G 41 21 40-50yrs -0.14 -1.16 0.63 1206.20 1.00 378 40 20 1 FALSE 0.12
colorectal cancer KRAS_G12V PIK3C2G 86 32 50-65yrs -0.15 -1.07 0.56 1039.38 1.00 830 84 30 2 FALSE 0.14
colorectal cancer KRAS_G12V PIK3C2G 55 28 >65yrs -0.07 -0.95 0.73 1017.54 1.00 557 51 24 4 FALSE 0.06
non-small cell lung cancer KRAS_G12V PIK3C2G 62 51 50-65yrs -2.17 -5.25 -0.19 509.07 1.01 1200 61 50 1 FALSE 1.12
non-small cell lung cancer KRAS_G12V PIK3C2G 100 73 >65yrs -2.38 -5.52 -0.47 584.35 1.00 1953 100 73 0 FALSE 1.14
colorectal cancer KRAS_G12V PIK3C2G 182 81 Age:overall -0.12 -1.01 0.64 1067.77 1.00 1765 175 74 7 FALSE 0.11
non-small cell lung cancer KRAS_G12V PIK3C2G 162 124 Age:overall -2.25 -5.34 -0.28 527.68 1.01 3153 161 123 1 FALSE 1.15
non-small cell lung cancer KRAS_G12V TSHR 62 23 50-65yrs -0.19 -1.66 1.00 972.19 1.00 1231 61 22 1 TRUE 0.10
non-small cell lung cancer KRAS_G12V TSHR 100 42 >65yrs -0.18 -1.57 0.97 980.19 1.00 1991 98 40 2 TRUE 0.10
non-small cell lung cancer KRAS_G12V TSHR 162 65 Age:overall -0.18 -1.79 1.05 942.35 1.00 3222 159 62 3 TRUE 0.10
colorectal cancer KRAS_G12V CREBBP 13 18 <40yrs -1.00 -2.09 -0.02 1423.99 1.00 191 12 17 1 TRUE 1.24
colorectal cancer KRAS_G12V CREBBP 42 31 40-50yrs -1.08 -2.17 -0.18 1421.22 1.00 387 41 30 1 TRUE 1.48
colorectal cancer KRAS_G12V CREBBP 90 58 50-65yrs -1.08 -2.06 -0.22 1480.17 1.00 835 88 56 2 TRUE 1.64
colorectal cancer KRAS_G12V CREBBP 59 81 >65yrs -1.03 -1.96 -0.22 1339.32 1.00 531 56 78 3 TRUE 1.68
non-small cell lung cancer KRAS_G12V CREBBP 62 48 50-65yrs 0.45 -0.34 1.27 310.77 1.01 1213 57 43 5 TRUE 0.54
non-small cell lung cancer KRAS_G12V CREBBP 100 83 >65yrs 0.30 -0.49 0.98 358.23 1.00 1954 96 79 4 TRUE 0.35
uterine cancer KRAS_G12V CREBBP 7 13 40-50yrs -0.45 -2.36 0.92 1464.13 1.00 74 7 13 0 TRUE 0.23
uterine cancer KRAS_G12V CREBBP 34 51 50-65yrs -0.36 -1.57 0.65 1399.61 1.00 442 32 49 2 TRUE 0.28
uterine cancer KRAS_G12V CREBBP 18 31 >65yrs 0.10 -1.18 1.35 664.90 1.00 438 15 28 3 TRUE 0.06
colorectal cancer KRAS_G12V CREBBP 204 188 Age:overall -1.05 -2.00 -0.22 1432.51 1.00 1944 197 181 7 TRUE 1.68
non-small cell lung cancer KRAS_G12V CREBBP 162 131 Age:overall 0.37 -0.46 1.13 356.57 1.00 3167 153 122 9 TRUE 0.38
uterine cancer KRAS_G12V CREBBP 59 95 Age:overall -0.23 -1.62 0.99 1515.22 1.00 954 54 90 5 TRUE 0.14
non-small cell lung cancer KRAS_G12V BRIP1 62 30 50-65yrs -1.99 -4.04 0.02 21.24 1.07 1224 62 30 0 TRUE 1.25
non-small cell lung cancer KRAS_G12V BRIP1 100 40 >65yrs -1.89 -3.84 0.09 10.02 1.12 1989 99 39 1 TRUE 1.23
non-small cell lung cancer KRAS_G12V BRIP1 162 70 Age:overall -1.94 -3.94 0.11 13.60 1.10 3213 161 69 1 TRUE 1.21
colorectal cancer KRAS_G12V AXIN2 42 25 40-50yrs -1.15 -2.26 -0.18 510.51 1.00 390 41 24 1 TRUE 1.43
colorectal cancer KRAS_G12V AXIN2 90 45 50-65yrs -1.18 -2.28 -0.21 502.41 1.00 840 89 44 1 TRUE 1.50
colorectal cancer KRAS_G12V AXIN2 59 39 >65yrs -1.14 -2.26 -0.16 482.09 1.00 558 57 37 2 TRUE 1.41
non-small cell lung cancer KRAS_G12V AXIN2 62 28 50-65yrs 0.90 -0.11 1.80 1116.08 1.00 1229 58 24 4 TRUE 1.18
non-small cell lung cancer KRAS_G12V AXIN2 100 30 >65yrs 0.66 -0.49 1.52 709.26 1.00 2000 98 28 2 TRUE 0.65
uterine cancer KRAS_G12V AXIN2 34 26 50-65yrs -0.43 -2.20 1.01 732.90 1.00 457 32 24 2 TRUE 0.22
uterine cancer KRAS_G12V AXIN2 17 22 >65yrs -0.99 -4.14 0.92 1128.43 1.00 439 17 22 0 TRUE 0.36
colorectal cancer KRAS_G12V AXIN2 191 109 Age:overall -1.15 -2.26 -0.18 488.71 1.00 1788 187 105 4 TRUE 1.47
non-small cell lung cancer KRAS_G12V AXIN2 162 58 Age:overall 0.78 -0.39 1.82 1373.86 1.00 3229 156 52 6 TRUE 0.71
uterine cancer KRAS_G12V AXIN2 51 48 Age:overall -0.68 -3.07 1.22 1107.45 1.00 896 49 46 2 TRUE 0.27
colorectal cancer KRAS_G12V DOT1L 13 19 <40yrs -1.03 -2.66 0.37 1507.43 1.00 190 12 18 1 FALSE 0.73
colorectal cancer KRAS_G12V DOT1L 42 12 40-50yrs -1.05 -2.70 0.32 1431.91 1.00 398 41 11 1 FALSE 0.78
colorectal cancer KRAS_G12V DOT1L 90 21 50-65yrs -1.37 -3.19 -0.01 1415.18 1.00 860 90 21 0 FALSE 1.02
colorectal cancer KRAS_G12V DOT1L 59 32 >65yrs -1.19 -2.78 0.02 1472.22 1.00 563 58 31 1 FALSE 1.02
non-small cell lung cancer KRAS_G12V DOT1L 62 35 50-65yrs 0.13 -0.86 1.34 50.08 1.04 1223 58 31 4 FALSE 0.10
non-small cell lung cancer KRAS_G12V DOT1L 100 66 >65yrs -0.27 -2.04 0.64 41.67 1.04 1965 99 65 1 FALSE 0.18
colorectal cancer KRAS_G12V DOT1L 204 84 Age:overall -1.17 -2.68 0.00 1496.67 1.00 2011 201 81 3 FALSE 1.04
non-small cell lung cancer KRAS_G12V DOT1L 162 101 Age:overall -0.06 -1.32 1.04 1276.96 1.00 3188 157 96 5 FALSE 0.03
colorectal cancer KRAS_G12V PTPRS 12 26 <40yrs -0.63 -1.34 0.02 748.96 1.00 181 10 24 2 FALSE 1.15
colorectal cancer KRAS_G12V PTPRS 41 51 40-50yrs -0.62 -1.29 0.01 777.80 1.01 359 37 47 4 FALSE 1.17
colorectal cancer KRAS_G12V PTPRS 86 98 50-65yrs -0.66 -1.33 -0.09 794.25 1.01 779 82 94 4 FALSE 1.37
colorectal cancer KRAS_G12V PTPRS 55 79 >65yrs -0.66 -1.34 -0.08 768.36 1.00 514 52 76 3 FALSE 1.33
non-small cell lung cancer KRAS_G12V PTPRS 62 31 50-65yrs 0.32 -1.01 1.23 468.34 1.01 1217 61 30 1 FALSE 0.23
non-small cell lung cancer KRAS_G12V PTPRS 100 46 >65yrs 0.56 -0.39 1.41 1017.35 1.00 1986 95 41 5 FALSE 0.65
uterine cancer KRAS_G12V PTPRS 32 42 50-65yrs -1.78 -4.56 0.05 1025.60 1.00 428 31 41 1 FALSE 0.88
uterine cancer KRAS_G12V PTPRS 17 27 >65yrs -2.05 -5.50 0.17 971.24 1.00 413 17 27 0 FALSE 0.82
colorectal cancer KRAS_G12V PTPRS 194 254 Age:overall -0.64 -1.32 -0.08 766.21 1.00 1833 181 241 13 FALSE 1.33
non-small cell lung cancer KRAS_G12V PTPRS 162 77 Age:overall 0.43 -0.82 1.39 955.87 1.00 3203 156 71 6 FALSE 0.34
uterine cancer KRAS_G12V PTPRS 49 69 Age:overall -1.90 -4.93 0.23 1080.32 1.00 841 48 68 1 FALSE 0.84
colorectal cancer KRAS_G12V SMARCA4 13 19 <40yrs -1.92 -3.49 -0.70 567.33 1.01 190 13 19 0 FALSE 2.05
colorectal cancer KRAS_G12V SMARCA4 42 24 40-50yrs -1.93 -3.47 -0.76 659.58 1.01 388 42 24 0 FALSE 2.22
colorectal cancer KRAS_G12V SMARCA4 90 65 50-65yrs -1.80 -3.19 -0.68 715.62 1.01 831 87 62 3 FALSE 2.21
colorectal cancer KRAS_G12V SMARCA4 59 61 >65yrs -1.97 -3.58 -0.76 810.22 1.00 542 59 61 0 FALSE 2.23
non-small cell lung cancer KRAS_G12V SMARCA4 6 19 40-50yrs 0.44 -0.30 1.17 1191.67 1.00 168 5 18 1 FALSE 0.66
non-small cell lung cancer KRAS_G12V SMARCA4 62 119 50-65yrs 0.59 0.01 1.27 1143.92 1.00 1150 49 106 13 FALSE 1.22
non-small cell lung cancer KRAS_G12V SMARCA4 100 174 >65yrs 0.29 -0.40 0.81 948.89 1.00 1879 93 167 7 FALSE 0.47
uterine cancer KRAS_G12V SMARCA4 34 53 50-65yrs -2.11 -5.09 -0.24 1407.30 1.00 443 33 52 1 FALSE 1.08
uterine cancer KRAS_G12V SMARCA4 17 35 >65yrs -2.43 -6.02 -0.18 1265.56 1.00 433 17 35 0 FALSE 0.94
colorectal cancer KRAS_G12V SMARCA4 204 169 Age:overall -1.91 -3.41 -0.74 690.39 1.01 1951 201 166 3 FALSE 2.31
non-small cell lung cancer KRAS_G12V SMARCA4 168 312 Age:overall 0.44 -0.16 1.00 1115.90 1.00 3197 147 291 21 FALSE 0.84
uterine cancer KRAS_G12V SMARCA4 51 88 Age:overall -2.24 -5.48 -0.09 1373.68 1.00 876 50 87 1 FALSE 0.99
colorectal cancer KRAS_G12V PTPRT 13 18 <40yrs -0.45 -1.18 0.23 933.02 1.00 191 12 17 1 FALSE 0.67
colorectal cancer KRAS_G12V PTPRT 42 39 40-50yrs -0.43 -1.15 0.25 796.22 1.00 380 39 36 3 FALSE 0.68
colorectal cancer KRAS_G12V PTPRT 90 80 50-65yrs -0.41 -1.10 0.25 787.27 1.00 809 83 73 7 FALSE 0.64
colorectal cancer KRAS_G12V PTPRT 59 48 >65yrs -0.47 -1.22 0.21 879.05 1.00 547 58 47 1 FALSE 0.73
non-small cell lung cancer KRAS_G12V PTPRT 6 22 40-50yrs -0.03 -0.75 0.74 1241.23 1.00 166 5 21 1 FALSE 0.02
non-small cell lung cancer KRAS_G12V PTPRT 64 152 50-65yrs 0.00 -0.61 0.59 1051.26 1.00 1145 56 144 8 FALSE 0.00
non-small cell lung cancer KRAS_G12V PTPRT 100 175 >65yrs -0.09 -0.73 0.48 1370.86 1.00 1882 93 168 7 FALSE 0.11
uterine cancer KRAS_G12V PTPRT 7 12 40-50yrs -1.39 -3.58 0.24 1274.09 1.00 78 7 12 0 FALSE 0.78
uterine cancer KRAS_G12V PTPRT 34 45 50-65yrs -1.14 -2.90 0.26 1314.23 1.00 445 32 43 2 FALSE 0.79
uterine cancer KRAS_G12V PTPRT 17 30 >65yrs -1.43 -3.67 0.15 1288.72 1.00 432 17 30 0 FALSE 0.82
colorectal cancer KRAS_G12V PTPRT 204 185 Age:overall -0.44 -1.15 0.20 814.60 1.00 1927 192 173 12 FALSE 0.72
non-small cell lung cancer KRAS_G12V PTPRT 170 349 Age:overall -0.05 -0.68 0.58 1295.06 1.00 3193 154 333 16 FALSE 0.05
uterine cancer KRAS_G12V PTPRT 58 87 Age:overall -1.31 -3.32 0.18 1306.37 1.00 955 56 85 2 FALSE 0.85
colorectal cancer KRAS_G12V HGF 90 24 50-65yrs -2.00 -4.66 0.00 578.98 1.01 855 90 24 0 FALSE 1.02
colorectal cancer KRAS_G12V HGF 59 15 >65yrs -1.81 -4.42 0.24 206.23 1.01 577 58 14 1 FALSE 0.92
non-small cell lung cancer KRAS_G12V HGF 62 78 50-65yrs -0.51 -1.74 0.36 623.77 1.01 1181 61 77 1 FALSE 0.47
non-small cell lung cancer KRAS_G12V HGF 100 105 >65yrs -0.22 -1.10 0.62 322.38 1.01 1937 94 99 6 FALSE 0.21
colorectal cancer KRAS_G12V HGF 149 39 Age:overall -1.89 -4.42 0.10 392.34 1.01 1432 148 38 1 FALSE 1.00
non-small cell lung cancer KRAS_G12V HGF 162 183 Age:overall -0.36 -1.40 0.56 523.10 1.00 3118 155 176 7 FALSE 0.31
colorectal cancer KRAS_G12V BLM 42 14 40-50yrs -5.51 -12.31 -1.37 942.11 1.00 398 42 14 0 TRUE 1.29
colorectal cancer KRAS_G12V BLM 90 21 50-65yrs -5.49 -12.14 -1.39 916.20 1.00 857 90 21 0 TRUE 1.28
colorectal cancer KRAS_G12V BLM 59 26 >65yrs -5.53 -12.22 -1.46 940.83 1.00 567 59 26 0 TRUE 1.30
colorectal cancer KRAS_G12V BLM 191 61 Age:overall -5.50 -12.15 -1.46 931.43 1.00 1822 191 61 0 TRUE 1.29
colorectal cancer KRAS_G12V PIK3CA 13 42 <40yrs 0.26 -0.24 0.68 1372.21 1.00 185 12 41 1 TRUE 0.57
colorectal cancer KRAS_G12V PIK3CA 46 90 40-50yrs 0.34 -0.06 0.73 1435.43 1.00 369 35 79 11 TRUE 1.02
colorectal cancer KRAS_G12V PIK3CA 108 213 50-65yrs 0.35 -0.01 0.69 1223.77 1.00 802 81 186 27 TRUE 1.33
colorectal cancer KRAS_G12V PIK3CA 63 166 >65yrs 0.37 0.00 0.75 1316.16 1.00 534 43 146 20 TRUE 1.32
non-small cell lung cancer KRAS_G12V PIK3CA 63 90 50-65yrs -0.34 -1.22 0.45 1166.39 1.00 1227 59 86 4 TRUE 0.39
non-small cell lung cancer KRAS_G12V PIK3CA 106 140 >65yrs -0.41 -1.26 0.25 1033.24 1.00 1948 102 136 4 TRUE 0.53
uterine cancer KRAS_G12V PIK3CA 9 45 40-50yrs -0.05 -0.84 0.67 1349.99 1.00 60 6 42 3 TRUE 0.04
uterine cancer KRAS_G12V PIK3CA 47 271 50-65yrs 0.12 -0.43 0.63 1372.35 1.00 355 25 249 22 TRUE 0.18
uterine cancer KRAS_G12V PIK3CA 19 226 >65yrs -0.19 -0.95 0.46 1390.81 1.00 316 13 220 6 TRUE 0.22
colorectal cancer KRAS_G12V PIK3CA 230 511 Age:overall 0.33 -0.03 0.68 1382.53 1.00 1890 171 452 59 TRUE 1.17
non-small cell lung cancer KRAS_G12V PIK3CA 169 230 Age:overall -0.37 -1.27 0.38 1225.83 1.00 3175 161 222 8 TRUE 0.42
uterine cancer KRAS_G12V PIK3CA 75 557 Age:overall -0.06 -0.74 0.58 1411.85 1.00 753 44 526 31 TRUE 0.06
non-small cell lung cancer KRAS_G12V GATA3 62 27 50-65yrs -0.62 -2.36 0.89 342.64 1.00 1229 61 26 1 FALSE 0.34
non-small cell lung cancer KRAS_G12V GATA3 100 36 >65yrs -0.65 -2.41 0.79 376.58 1.00 1995 99 35 1 FALSE 0.37
non-small cell lung cancer KRAS_G12V GATA3 162 63 Age:overall -0.62 -2.42 0.86 385.00 1.00 3224 160 61 2 FALSE 0.34
colorectal cancer KRAS_G12V ESR1 13 12 <40yrs -1.43 -3.49 0.08 1075.06 1.00 193 13 12 0 TRUE 0.89
colorectal cancer KRAS_G12V ESR1 90 24 50-65yrs -1.52 -3.52 -0.02 1060.67 1.00 853 90 24 0 TRUE 1.04
colorectal cancer KRAS_G12V ESR1 59 28 >65yrs -1.19 -2.89 0.21 1100.86 1.00 567 57 26 2 TRUE 0.87
non-small cell lung cancer KRAS_G12V ESR1 62 18 50-65yrs -1.36 -4.20 0.53 253.04 1.02 1236 62 18 0 TRUE 0.58
non-small cell lung cancer KRAS_G12V ESR1 100 34 >65yrs -1.27 -4.05 0.52 276.02 1.02 1997 99 33 1 TRUE 0.59
colorectal cancer KRAS_G12V ESR1 162 64 Age:overall -1.38 -3.21 0.06 979.46 1.00 1613 160 62 2 TRUE 1.02
non-small cell lung cancer KRAS_G12V ESR1 162 52 Age:overall -1.30 -4.17 0.67 308.17 1.02 3233 161 51 1 TRUE 0.56
colorectal cancer KRAS_G12V ALK 13 14 <40yrs -1.52 -2.86 -0.39 1176.54 1.00 216 13 14 0 TRUE 1.92
colorectal cancer KRAS_G12V ALK 45 25 40-50yrs -1.53 -2.88 -0.42 1180.82 1.00 420 45 25 0 TRUE 1.95
colorectal cancer KRAS_G12V ALK 106 44 50-65yrs -1.53 -2.78 -0.45 1189.87 1.00 926 105 43 1 TRUE 2.03
colorectal cancer KRAS_G12V ALK 62 32 >65yrs -1.48 -2.79 -0.38 1087.39 1.00 631 60 30 2 TRUE 1.88
non-small cell lung cancer KRAS_G12V ALK 63 76 50-65yrs 0.24 -0.66 0.97 1486.68 1.00 1245 59 72 4 TRUE 0.24
non-small cell lung cancer KRAS_G12V ALK 106 81 >65yrs 0.33 -0.48 1.07 1439.90 1.00 2005 100 75 6 TRUE 0.40
uterine cancer KRAS_G12V ALK 39 25 50-65yrs -4.92 -11.64 -0.67 1072.57 1.00 517 39 25 0 TRUE 1.05
uterine cancer KRAS_G12V ALK 19 20 >65yrs -4.86 -11.71 -0.56 1109.09 1.00 484 19 20 0 TRUE 1.02
colorectal cancer KRAS_G12V ALK 226 115 Age:overall -1.52 -2.80 -0.42 1177.36 1.00 2193 223 112 3 TRUE 1.98
non-small cell lung cancer KRAS_G12V ALK 169 157 Age:overall 0.29 -0.73 1.26 1510.66 1.00 3250 159 147 10 TRUE 0.24
uterine cancer KRAS_G12V ALK 58 45 Age:overall -4.82 -11.43 -0.53 1149.77 1.00 1001 58 45 0 TRUE 1.04
colorectal cancer KRAS_G12V RNF43 13 31 <40yrs -1.72 -3.55 -0.09 1518.27 1.00 181 12 30 1 TRUE 1.37
colorectal cancer KRAS_G12V RNF43 42 26 40-50yrs -1.12 -2.81 0.39 1626.35 1.00 388 39 23 3 TRUE 0.76
colorectal cancer KRAS_G12V RNF43 90 87 50-65yrs -2.51 -4.64 -1.08 1187.42 1.00 808 90 87 0 TRUE 2.41
colorectal cancer KRAS_G12V RNF43 59 123 >65yrs -2.63 -4.73 -1.29 1377.71 1.00 508 59 123 0 TRUE 2.50
pancreatic cancer KRAS_G12V RNF43 157 21 50-65yrs 0.33 -0.38 1.15 1463.49 1.00 447 149 13 8 TRUE 0.40
pancreatic cancer KRAS_G12V RNF43 216 52 >65yrs 0.10 -0.51 0.68 1309.40 1.00 509 201 37 15 TRUE 0.13
uterine cancer KRAS_G12V RNF43 8 12 40-50yrs 0.07 -1.16 1.26 1022.34 1.00 76 6 10 2 TRUE 0.04
uterine cancer KRAS_G12V RNF43 34 40 50-65yrs -0.29 -1.73 0.70 959.48 1.00 446 33 39 1 TRUE 0.20
uterine cancer KRAS_G12V RNF43 18 41 >65yrs -0.07 -1.32 0.94 851.05 1.00 424 16 39 2 TRUE 0.05
colorectal cancer KRAS_G12V RNF43 204 267 Age:overall -1.97 -3.44 -0.77 1348.20 1.00 1885 200 263 4 TRUE 2.49
pancreatic cancer KRAS_G12V RNF43 373 73 Age:overall 0.19 -1.03 1.28 1357.07 1.00 956 350 50 23 TRUE 0.13
uterine cancer KRAS_G12V RNF43 60 93 Age:overall -0.10 -1.29 0.91 999.74 1.00 946 55 88 5 TRUE 0.06
non-small cell lung cancer KRAS_G12V U2AF1 62 24 50-65yrs -0.32 -4.52 1.25 915.83 1.00 1229 62 24 0 FALSE 0.07
non-small cell lung cancer KRAS_G12V U2AF1 100 51 >65yrs 1.07 0.16 1.89 889.48 1.00 1987 92 43 8 FALSE 1.86
non-small cell lung cancer KRAS_G12V U2AF1 162 75 Age:overall 0.43 -2.17 2.09 1315.44 1.00 3216 154 67 8 FALSE 0.15
colorectal cancer KRAS_G12V LATS1 86 26 50-65yrs -5.13 -11.98 -1.08 1118.96 1.00 832 86 26 0 FALSE 1.14
colorectal cancer KRAS_G12V LATS1 55 14 >65yrs -5.10 -12.08 -1.13 1121.05 1.00 564 55 14 0 FALSE 1.11
non-small cell lung cancer KRAS_G12V LATS1 62 27 50-65yrs -0.02 -1.43 1.23 108.50 1.03 1223 60 25 2 FALSE 0.01
non-small cell lung cancer KRAS_G12V LATS1 100 37 >65yrs -0.17 -1.75 1.20 118.80 1.02 1985 99 36 1 FALSE 0.09
colorectal cancer KRAS_G12V LATS1 141 40 Age:overall -5.07 -12.17 -1.01 1181.25 1.00 1396 141 40 0 FALSE 1.13
non-small cell lung cancer KRAS_G12V LATS1 162 64 Age:overall -0.11 -1.61 1.26 128.81 1.02 3208 159 61 3 FALSE 0.05
colorectal cancer KRAS_G12V LATS2 86 35 50-65yrs -5.34 -11.21 -1.44 184.31 1.00 821 86 35 0 FALSE 1.35
colorectal cancer KRAS_G12V LATS2 55 21 >65yrs -5.32 -11.26 -1.36 193.07 1.00 558 55 21 0 FALSE 1.33
non-small cell lung cancer KRAS_G12V LATS2 62 24 50-65yrs -0.38 -3.05 0.97 393.99 1.00 1226 62 24 0 FALSE 0.13
non-small cell lung cancer KRAS_G12V LATS2 100 36 >65yrs 0.02 -1.53 1.18 424.31 1.01 1988 97 33 3 FALSE 0.01
uterine cancer KRAS_G12V LATS2 32 24 50-65yrs -5.03 -12.14 -0.82 1270.09 1.00 441 32 24 0 FALSE 1.05
uterine cancer KRAS_G12V LATS2 17 22 >65yrs -4.99 -11.98 -0.56 1315.70 1.00 415 17 22 0 FALSE 1.01
colorectal cancer KRAS_G12V LATS2 141 56 Age:overall -5.30 -11.14 -1.31 175.41 1.00 1379 141 56 0 FALSE 1.34
non-small cell lung cancer KRAS_G12V LATS2 162 60 Age:overall -0.17 -2.24 1.23 580.57 1.01 3214 159 57 3 FALSE 0.07
uterine cancer KRAS_G12V LATS2 49 46 Age:overall -4.93 -11.84 -0.58 1295.64 1.00 856 49 46 0 FALSE 1.03
colorectal cancer KRAS_G12V PTEN 13 16 <40yrs -0.49 -1.29 0.24 995.23 1.00 212 12 15 1 TRUE 0.68
colorectal cancer KRAS_G12V PTEN 45 45 40-50yrs -0.49 -1.23 0.22 992.48 1.00 409 42 42 3 TRUE 0.75
colorectal cancer KRAS_G12V PTEN 106 65 50-65yrs -0.51 -1.24 0.15 977.12 1.00 920 102 61 4 TRUE 0.84
colorectal cancer KRAS_G12V PTEN 62 59 >65yrs -0.51 -1.28 0.14 853.76 1.00 620 59 56 3 TRUE 0.81
non-small cell lung cancer KRAS_G12V PTEN 63 40 50-65yrs -5.27 -11.54 -1.62 928.72 1.00 1272 63 40 0 TRUE 1.38
non-small cell lung cancer KRAS_G12V PTEN 106 87 >65yrs -5.26 -11.52 -1.74 699.68 1.00 1995 106 87 0 TRUE 1.44
uterine cancer KRAS_G12V PTEN 12 69 40-50yrs 0.43 -0.32 1.24 1520.64 1.00 53 4 61 8 TRUE 0.54
uterine cancer KRAS_G12V PTEN 47 321 50-65yrs 0.04 -0.52 0.56 1498.74 1.00 351 27 301 20 TRUE 0.05
uterine cancer KRAS_G12V PTEN 22 223 >65yrs 0.28 -0.36 1.00 1450.94 1.00 361 11 212 11 TRUE 0.38
colorectal cancer KRAS_G12V PTEN 226 185 Age:overall -0.50 -1.21 0.15 919.74 1.00 2161 215 174 11 TRUE 0.82
non-small cell lung cancer KRAS_G12V PTEN 169 127 Age:overall -5.20 -11.32 -1.58 867.24 1.00 3267 169 127 0 TRUE 1.42
uterine cancer KRAS_G12V PTEN 81 627 Age:overall 0.21 -0.53 0.92 1422.30 1.00 787 42 588 39 TRUE 0.24
colorectal cancer KRAS_G12V BCOR 13 11 <40yrs -0.93 -2.22 0.16 1344.61 1.00 195 13 11 0 FALSE 0.95
colorectal cancer KRAS_G12V BCOR 42 14 40-50yrs -0.87 -2.04 0.16 1365.44 1.00 396 41 13 1 FALSE 0.92
colorectal cancer KRAS_G12V BCOR 90 40 50-65yrs -0.79 -1.84 0.15 1291.12 1.00 846 87 37 3 FALSE 0.91
colorectal cancer KRAS_G12V BCOR 59 47 >65yrs -0.97 -2.18 -0.02 1383.72 1.00 553 58 46 1 FALSE 1.10
non-small cell lung cancer KRAS_G12V BCOR 63 46 50-65yrs 0.90 -0.10 1.64 236.88 1.01 1217 56 39 7 FALSE 1.64
non-small cell lung cancer KRAS_G12V BCOR 100 84 >65yrs 0.70 -0.13 1.35 265.02 1.01 1957 94 78 6 FALSE 1.22
uterine cancer KRAS_G12V BCOR 7 12 40-50yrs -0.66 -2.13 0.83 895.01 1.00 74 6 11 1 FALSE 0.45
uterine cancer KRAS_G12V BCOR 34 65 50-65yrs -1.13 -3.04 0.04 1150.79 1.00 422 34 65 0 FALSE 0.87
uterine cancer KRAS_G12V BCOR 17 58 >65yrs -0.52 -1.77 0.77 570.94 1.01 415 14 55 3 FALSE 0.38
colorectal cancer KRAS_G12V BCOR 204 112 Age:overall -0.89 -1.95 0.01 1289.03 1.00 1990 199 107 5 FALSE 1.11
non-small cell lung cancer KRAS_G12V BCOR 163 130 Age:overall 0.79 -0.15 1.59 235.67 1.01 3174 150 117 13 FALSE 1.11
uterine cancer KRAS_G12V BCOR 58 135 Age:overall -0.75 -2.08 0.45 1046.38 1.01 911 54 131 4 FALSE 0.66
colorectal cancer KRAS_G12V CTNNB1 13 20 <40yrs -0.19 -0.96 0.50 1260.22 1.00 205 12 19 1 TRUE 0.22
colorectal cancer KRAS_G12V CTNNB1 45 27 40-50yrs -0.16 -0.85 0.50 1307.77 1.00 417 42 24 3 TRUE 0.19
colorectal cancer KRAS_G12V CTNNB1 107 76 50-65yrs -0.19 -0.86 0.39 1215.02 1.00 901 101 70 6 TRUE 0.25
colorectal cancer KRAS_G12V CTNNB1 62 40 >65yrs -0.19 -0.86 0.43 1153.54 1.00 623 59 37 3 TRUE 0.24
non-small cell lung cancer KRAS_G12V CTNNB1 63 43 50-65yrs -1.22 -2.94 0.10 574.53 1.00 1269 62 42 1 TRUE 0.91
non-small cell lung cancer KRAS_G12V CTNNB1 106 71 >65yrs -1.27 -3.01 0.01 517.36 1.00 2009 105 70 1 TRUE 0.96
uterine cancer KRAS_G12V CTNNB1 8 13 40-50yrs -0.74 -2.43 0.86 1376.58 1.00 74 7 12 1 TRUE 0.42
uterine cancer KRAS_G12V CTNNB1 39 59 50-65yrs -0.90 -2.18 0.18 1515.64 1.00 481 37 57 2 TRUE 0.86
uterine cancer KRAS_G12V CTNNB1 19 58 >65yrs -0.96 -2.62 0.40 1482.07 1.00 447 18 57 1 TRUE 0.68
colorectal cancer KRAS_G12V CTNNB1 227 163 Age:overall -0.17 -0.85 0.42 1237.06 1.00 2146 214 150 13 TRUE 0.23
non-small cell lung cancer KRAS_G12V CTNNB1 169 114 Age:overall -1.25 -2.99 0.10 546.43 1.00 3278 167 112 2 TRUE 0.91
uterine cancer KRAS_G12V CTNNB1 66 143 Age:overall -0.89 -2.30 0.48 1472.13 1.00 1022 62 139 4 TRUE 0.66
cancer of unknown primary KRAS_G12V ARID1A 30 50 50-65yrs 0.70 -0.24 1.58 1453.10 1.00 253 21 41 9 TRUE 0.90
cancer of unknown primary KRAS_G12V ARID1A 23 49 >65yrs -1.59 -4.99 0.34 1303.88 1.00 301 23 49 0 TRUE 0.57
colorectal cancer KRAS_G12V ARID1A 13 40 <40yrs -0.68 -1.49 0.05 1350.08 1.00 180 12 39 1 TRUE 1.13
colorectal cancer KRAS_G12V ARID1A 43 51 40-50yrs -0.49 -1.21 0.35 907.51 1.00 380 37 45 6 TRUE 0.68
colorectal cancer KRAS_G12V ARID1A 90 114 50-65yrs -0.76 -1.42 -0.14 1350.25 1.00 795 86 110 4 TRUE 1.66
colorectal cancer KRAS_G12V ARID1A 59 110 >65yrs -0.68 -1.35 -0.07 1300.35 1.00 520 54 105 5 TRUE 1.43
non-small cell lung cancer KRAS_G12V ARID1A 6 16 40-50yrs -0.10 -0.99 0.61 908.72 1.00 170 6 16 0 TRUE 0.09
non-small cell lung cancer KRAS_G12V ARID1A 63 117 50-65yrs -0.07 -0.79 0.53 853.06 1.00 1151 58 112 5 TRUE 0.08
non-small cell lung cancer KRAS_G12V ARID1A 101 149 >65yrs -0.05 -0.70 0.53 779.51 1.00 1899 93 141 8 TRUE 0.05
pancreatic cancer KRAS_G12V ARID1A 158 50 50-65yrs 0.17 -0.47 0.83 936.78 1.00 427 141 33 17 TRUE 0.20
pancreatic cancer KRAS_G12V ARID1A 215 68 >65yrs -0.65 -1.35 -0.06 1345.05 1.00 491 205 58 10 TRUE 1.26
uterine cancer KRAS_G12V ARID1A 10 47 40-50yrs 0.95 0.20 1.92 1283.27 1.00 55 3 40 7 TRUE 1.63
uterine cancer KRAS_G12V ARID1A 38 258 50-65yrs 0.56 -0.07 1.15 1337.34 1.00 321 20 240 18 TRUE 1.14
uterine cancer KRAS_G12V ARID1A 22 212 >65yrs 0.93 0.31 1.76 1097.72 1.00 333 6 196 16 TRUE 1.96
cancer of unknown primary KRAS_G12V ARID1A 54 110 Age:overall -0.56 -3.16 1.14 1271.86 1.00 626 45 101 9 TRUE 0.21
colorectal cancer KRAS_G12V ARID1A 205 315 Age:overall -0.65 -1.29 -0.06 1368.88 1.00 1875 189 299 16 TRUE 1.39
non-small cell lung cancer KRAS_G12V ARID1A 170 282 Age:overall -0.07 -0.77 0.55 821.05 1.00 3220 157 269 13 TRUE 0.07
pancreatic cancer KRAS_G12V ARID1A 373 118 Age:overall -0.22 -1.47 1.09 1270.87 1.00 918 346 91 27 TRUE 0.14
uterine cancer KRAS_G12V ARID1A 70 517 Age:overall 0.81 0.13 1.59 1155.04 1.00 709 29 476 41 TRUE 1.60
colorectal cancer KRAS_G12V PIK3R1 13 11 <40yrs -0.53 -1.47 0.28 726.54 1.01 195 13 11 0 TRUE 0.62
colorectal cancer KRAS_G12V PIK3R1 42 21 40-50yrs -0.55 -1.54 0.28 776.85 1.00 390 42 21 0 TRUE 0.65
colorectal cancer KRAS_G12V PIK3R1 90 48 50-65yrs -0.45 -1.30 0.32 746.91 1.00 842 84 42 6 TRUE 0.56
colorectal cancer KRAS_G12V PIK3R1 59 36 >65yrs -0.54 -1.45 0.24 726.66 1.01 562 58 35 1 TRUE 0.67
non-small cell lung cancer KRAS_G12V PIK3R1 62 18 50-65yrs -0.21 -2.36 1.01 707.35 1.00 1235 62 18 0 TRUE 0.09
non-small cell lung cancer KRAS_G12V PIK3R1 100 35 >65yrs 0.11 -1.26 1.17 625.79 1.00 1998 97 32 3 TRUE 0.06
uterine cancer KRAS_G12V PIK3R1 7 14 40-50yrs -0.22 -1.31 0.80 1470.88 1.00 72 6 13 1 TRUE 0.17
uterine cancer KRAS_G12V PIK3R1 36 119 50-65yrs -0.19 -0.97 0.52 1131.74 1.00 390 29 112 7 TRUE 0.21
uterine cancer KRAS_G12V PIK3R1 17 130 >65yrs -0.24 -1.12 0.56 1370.98 1.00 358 13 126 4 TRUE 0.24
colorectal cancer KRAS_G12V PIK3R1 204 116 Age:overall -0.52 -1.35 0.26 671.23 1.00 1989 197 109 7 TRUE 0.66
non-small cell lung cancer KRAS_G12V PIK3R1 162 53 Age:overall -0.04 -1.65 1.24 745.76 1.00 3233 159 50 3 TRUE 0.02
uterine cancer KRAS_G12V PIK3R1 60 263 Age:overall -0.21 -1.10 0.68 1176.53 1.00 820 48 251 12 TRUE 0.19
colorectal cancer KRAS_G12V IKZF1 42 13 40-50yrs -2.35 -4.96 -0.60 228.64 1.01 395 42 13 0 TRUE 1.38
colorectal cancer KRAS_G12V IKZF1 90 31 50-65yrs -2.29 -4.82 -0.60 253.83 1.01 850 89 30 1 TRUE 1.37
colorectal cancer KRAS_G12V IKZF1 59 33 >65yrs -2.37 -4.92 -0.64 221.30 1.01 560 59 33 0 TRUE 1.42
non-small cell lung cancer KRAS_G12V IKZF1 62 44 50-65yrs -1.72 -4.54 0.18 1512.32 1.00 1211 61 43 1 TRUE 0.82
non-small cell lung cancer KRAS_G12V IKZF1 100 34 >65yrs -2.20 -6.04 0.04 1331.18 1.00 1995 100 34 0 TRUE 0.81
colorectal cancer KRAS_G12V IKZF1 191 77 Age:overall -2.33 -4.90 -0.63 214.35 1.01 1805 190 76 1 TRUE 1.42
non-small cell lung cancer KRAS_G12V IKZF1 162 78 Age:overall -1.93 -5.08 0.39 1439.53 1.00 3206 161 77 1 TRUE 0.79
colorectal cancer KRAS_G12V TERT 43 23 40-50yrs -0.62 -1.76 0.27 811.91 1.00 394 41 21 2 TRUE 0.64
colorectal cancer KRAS_G12V TERT 90 39 50-65yrs -0.65 -1.73 0.20 820.17 1.00 841 88 37 2 TRUE 0.71
colorectal cancer KRAS_G12V TERT 59 27 >65yrs -0.66 -1.78 0.23 766.79 1.00 566 58 26 1 TRUE 0.69
non-small cell lung cancer KRAS_G12V TERT 62 59 50-65yrs -0.44 -1.53 0.48 719.40 1.00 1199 59 56 3 TRUE 0.40
non-small cell lung cancer KRAS_G12V TERT 100 99 >65yrs -0.55 -1.73 0.31 613.85 1.01 1938 98 97 2 TRUE 0.52
uterine cancer KRAS_G12V TERT 7 11 40-50yrs -1.56 -4.71 0.64 1362.50 1.00 74 6 10 1 TRUE 0.62
uterine cancer KRAS_G12V TERT 34 28 50-65yrs -2.00 -5.16 0.01 1418.09 1.00 451 34 28 0 TRUE 0.91
uterine cancer KRAS_G12V TERT 17 24 >65yrs -1.94 -5.11 0.14 1359.36 1.00 434 17 24 0 TRUE 0.75
colorectal cancer KRAS_G12V TERT 192 89 Age:overall -0.64 -1.77 0.22 774.54 1.00 1801 187 84 5 TRUE 0.67
non-small cell lung cancer KRAS_G12V TERT 162 158 Age:overall -0.49 -1.66 0.52 732.36 1.01 3137 157 153 5 TRUE 0.42
uterine cancer KRAS_G12V TERT 58 63 Age:overall -1.83 -4.87 0.14 1387.94 1.00 959 57 62 1 TRUE 0.84
colorectal cancer KRAS_G12V FAT1 13 24 <40yrs -1.28 -2.20 -0.47 173.90 1.02 192 12 23 1 FALSE 2.67
colorectal cancer KRAS_G12V FAT1 42 39 40-50yrs -1.27 -2.17 -0.52 156.64 1.02 386 40 37 2 FALSE 2.82
colorectal cancer KRAS_G12V FAT1 90 81 50-65yrs -1.29 -2.18 -0.61 76.27 1.04 827 87 78 3 FALSE 3.10
colorectal cancer KRAS_G12V FAT1 59 83 >65yrs -1.36 -2.35 -0.68 51.03 1.05 530 59 83 0 FALSE 2.92
non-small cell lung cancer KRAS_G12V FAT1 62 103 50-65yrs -0.46 -1.34 0.23 1095.39 1.00 1161 59 100 3 FALSE 0.61
non-small cell lung cancer KRAS_G12V FAT1 100 194 >65yrs -0.39 -1.10 0.24 1267.99 1.00 1864 93 187 7 FALSE 0.60
uterine cancer KRAS_G12V FAT1 7 32 40-50yrs -0.69 -2.49 0.72 1506.81 1.00 69 6 31 1 FALSE 0.42
uterine cancer KRAS_G12V FAT1 34 85 50-65yrs -1.19 -2.80 0.07 1559.00 1.00 435 33 84 1 FALSE 0.93
uterine cancer KRAS_G12V FAT1 18 58 >65yrs 0.45 -0.76 1.58 1369.96 1.00 421 13 53 5 FALSE 0.34
colorectal cancer KRAS_G12V FAT1 204 227 Age:overall -1.29 -2.19 -0.63 62.35 1.04 1935 198 221 6 FALSE 3.02
non-small cell lung cancer KRAS_G12V FAT1 162 297 Age:overall -0.41 -1.22 0.39 1334.48 1.00 3025 152 287 10 FALSE 0.48
uterine cancer KRAS_G12V FAT1 59 175 Age:overall -0.48 -2.02 0.89 1430.50 1.00 925 52 168 7 FALSE 0.28
colorectal cancer KRAS_G12V FGFR4 90 17 50-65yrs -1.66 -4.24 0.27 947.22 1.00 862 89 16 1 TRUE 0.80
colorectal cancer KRAS_G12V FGFR4 59 21 >65yrs -2.05 -5.25 0.02 1269.60 1.00 573 59 21 0 TRUE 0.86
colorectal cancer KRAS_G12V FGFR4 149 38 Age:overall -1.83 -4.58 0.23 1117.26 1.00 1435 148 37 1 TRUE 0.84
colorectal cancer KRAS_G12V CIC 13 15 <40yrs -0.66 -1.69 0.37 1546.84 1.00 193 12 14 1 TRUE 0.71
colorectal cancer KRAS_G12V CIC 42 25 40-50yrs -0.62 -1.63 0.27 1383.31 1.00 392 40 23 2 TRUE 0.69
colorectal cancer KRAS_G12V CIC 90 39 50-65yrs -0.71 -1.64 0.20 1502.38 1.00 846 88 37 2 TRUE 0.88
colorectal cancer KRAS_G12V CIC 59 58 >65yrs -0.74 -1.71 0.11 1428.66 1.00 548 57 56 2 TRUE 0.98
non-small cell lung cancer KRAS_G12V CIC 62 21 50-65yrs -0.44 -2.16 0.92 1280.64 1.00 1236 61 20 1 TRUE 0.24
non-small cell lung cancer KRAS_G12V CIC 100 66 >65yrs -0.50 -1.92 0.66 1181.17 1.00 1972 98 64 2 TRUE 0.35
uterine cancer KRAS_G12V CIC 34 37 50-65yrs -1.85 -7.16 0.51 1217.49 1.00 451 34 37 0 TRUE 0.46
uterine cancer KRAS_G12V CIC 18 25 >65yrs 0.67 -0.96 2.22 759.62 1.01 438 15 22 3 TRUE 0.37
colorectal cancer KRAS_G12V CIC 204 137 Age:overall -0.67 -1.57 0.13 1508.64 1.00 1979 197 130 7 TRUE 0.92
non-small cell lung cancer KRAS_G12V CIC 162 87 Age:overall -0.47 -2.19 0.97 1261.20 1.00 3208 159 84 3 TRUE 0.24
uterine cancer KRAS_G12V CIC 52 62 Age:overall -0.55 -3.78 1.96 1295.40 1.00 889 49 59 3 TRUE 0.15
colorectal cancer KRAS_G12V KDM6A 42 11 40-50yrs 0.25 -0.63 1.02 1166.50 1.00 399 41 10 1 FALSE 0.27
colorectal cancer KRAS_G12V KDM6A 90 26 50-65yrs 0.26 -0.58 1.04 1105.69 1.00 855 87 23 3 FALSE 0.28
colorectal cancer KRAS_G12V KDM6A 59 20 >65yrs 0.28 -0.56 1.06 1158.95 1.00 575 56 17 3 FALSE 0.31
non-small cell lung cancer KRAS_G12V KDM6A 62 27 50-65yrs -0.60 -2.63 0.81 821.83 1.00 1229 61 26 1 FALSE 0.33
non-small cell lung cancer KRAS_G12V KDM6A 100 33 >65yrs -0.62 -2.63 0.75 801.30 1.00 1998 99 32 1 FALSE 0.35
pancreatic cancer KRAS_G12V KDM6A 157 19 50-65yrs 0.33 -0.40 1.06 1077.32 1.00 448 150 12 7 FALSE 0.43
pancreatic cancer KRAS_G12V KDM6A 215 38 >65yrs 0.27 -0.41 0.91 1063.05 1.00 517 203 26 12 FALSE 0.37
uterine cancer KRAS_G12V KDM6A 34 29 50-65yrs -1.90 -5.65 0.29 963.96 1.00 454 34 29 0 FALSE 0.62
uterine cancer KRAS_G12V KDM6A 17 17 >65yrs -0.91 -3.81 1.25 1221.19 1.00 442 16 16 1 FALSE 0.32
colorectal cancer KRAS_G12V KDM6A 191 57 Age:overall 0.26 -0.57 1.04 1252.57 1.00 1829 184 50 7 FALSE 0.29
non-small cell lung cancer KRAS_G12V KDM6A 162 60 Age:overall -0.60 -2.61 0.87 840.15 1.00 3227 160 58 2 FALSE 0.32
pancreatic cancer KRAS_G12V KDM6A 372 57 Age:overall 0.29 -0.60 1.17 1224.84 1.00 965 353 38 19 FALSE 0.28
uterine cancer KRAS_G12V KDM6A 51 46 Age:overall -1.32 -4.61 1.07 1205.40 1.00 896 50 45 1 FALSE 0.45
colorectal cancer KRAS_G12V NCOR1 13 12 <40yrs -0.51 -1.43 0.34 346.59 1.00 197 12 11 1 FALSE 0.55
colorectal cancer KRAS_G12V NCOR1 45 22 40-50yrs -0.38 -1.31 0.60 283.38 1.00 393 40 17 5 FALSE 0.35
colorectal cancer KRAS_G12V NCOR1 90 56 50-65yrs -0.64 -1.53 0.14 368.60 1.00 832 89 55 1 FALSE 0.84
colorectal cancer KRAS_G12V NCOR1 59 45 >65yrs -0.60 -1.58 0.23 344.88 1.00 554 58 44 1 FALSE 0.74
non-small cell lung cancer KRAS_G12V NCOR1 62 41 50-65yrs -1.95 -4.85 -0.10 1333.84 1.00 1218 61 40 1 FALSE 0.98
non-small cell lung cancer KRAS_G12V NCOR1 100 56 >65yrs -2.12 -5.02 -0.31 1361.86 1.00 1977 100 56 0 FALSE 1.05
uterine cancer KRAS_G12V NCOR1 7 11 40-50yrs -5.43 -12.15 -1.27 1232.94 1.00 77 7 11 0 FALSE 1.24
uterine cancer KRAS_G12V NCOR1 34 50 50-65yrs -5.48 -11.80 -1.49 1257.86 1.00 450 34 50 0 FALSE 1.29
uterine cancer KRAS_G12V NCOR1 17 24 >65yrs -5.45 -11.98 -1.29 1225.18 1.00 438 17 24 0 FALSE 1.24
colorectal cancer KRAS_G12V NCOR1 207 135 Age:overall -0.53 -1.37 0.22 268.03 1.00 1976 199 127 8 FALSE 0.69
non-small cell lung cancer KRAS_G12V NCOR1 162 97 Age:overall -2.02 -4.91 -0.24 1320.51 1.00 3195 161 96 1 FALSE 1.01
uterine cancer KRAS_G12V NCOR1 58 85 Age:overall -5.42 -11.80 -1.44 1253.95 1.00 965 58 85 0 FALSE 1.27
colorectal cancer KRAS_G12V POLE 13 22 <40yrs -1.56 -2.95 -0.38 1005.12 1.01 191 11 20 2 TRUE 1.90
colorectal cancer KRAS_G12V POLE 42 23 40-50yrs -1.68 -3.14 -0.62 663.89 1.01 390 42 23 0 TRUE 2.16
colorectal cancer KRAS_G12V POLE 90 51 50-65yrs -1.66 -3.05 -0.63 660.95 1.01 837 89 50 1 TRUE 2.27
colorectal cancer KRAS_G12V POLE 59 45 >65yrs -1.72 -3.19 -0.71 437.41 1.01 552 59 45 0 TRUE 2.21
non-small cell lung cancer KRAS_G12V POLE 63 56 50-65yrs 0.83 0.06 1.75 144.78 1.02 1207 55 48 8 TRUE 1.18
non-small cell lung cancer KRAS_G12V POLE 100 75 >65yrs 0.03 -1.38 0.92 600.53 1.01 1961 98 73 2 TRUE 0.02
uterine cancer KRAS_G12V POLE 7 15 40-50yrs -2.60 -5.98 -0.40 280.00 1.00 72 7 15 0 TRUE 1.16
uterine cancer KRAS_G12V POLE 34 60 50-65yrs -2.38 -5.42 -0.51 214.64 1.00 445 33 59 1 TRUE 1.21
uterine cancer KRAS_G12V POLE 17 31 >65yrs -2.59 -6.05 -0.35 283.55 1.00 437 17 31 0 TRUE 1.16
colorectal cancer KRAS_G12V POLE 204 141 Age:overall -1.66 -3.04 -0.68 529.95 1.01 1970 201 138 3 TRUE 2.34
non-small cell lung cancer KRAS_G12V POLE 163 131 Age:overall 0.42 -1.05 1.62 1276.07 1.00 3168 153 121 10 TRUE 0.29
uterine cancer KRAS_G12V POLE 58 106 Age:overall -2.52 -5.59 -0.47 240.36 1.00 954 57 105 1 TRUE 1.24
non-small cell lung cancer KRAS_G12V CUL3 63 24 50-65yrs 0.21 -1.14 1.31 446.47 1.01 1234 60 21 3 FALSE 0.15
non-small cell lung cancer KRAS_G12V CUL3 100 50 >65yrs -0.08 -1.58 0.85 58.85 1.04 1984 99 49 1 FALSE 0.05
non-small cell lung cancer KRAS_G12V CUL3 163 74 Age:overall 0.07 -1.32 1.22 386.14 1.02 3218 159 70 4 FALSE 0.04
colorectal cancer KRAS_G12V ABL1 46 14 40-50yrs -1.04 -2.30 0.22 56.60 1.06 430 44 12 2 TRUE 0.86
colorectal cancer KRAS_G12V ABL1 106 29 50-65yrs -1.10 -2.34 0.15 57.76 1.06 944 105 28 1 TRUE 0.97
colorectal cancer KRAS_G12V ABL1 62 24 >65yrs -1.11 -2.35 0.11 61.22 1.06 635 62 24 0 TRUE 0.98
colorectal cancer KRAS_G12V ABL1 214 67 Age:overall -1.08 -2.32 0.17 56.83 1.06 2009 211 64 3 TRUE 0.96
colorectal cancer KRAS_G12V FOXP1 13 12 <40yrs -1.00 -2.37 0.33 436.57 1.01 195 12 11 1 FALSE 0.87
colorectal cancer KRAS_G12V FOXP1 42 17 40-50yrs -1.08 -2.50 0.07 763.63 1.01 393 42 17 0 FALSE 1.02
colorectal cancer KRAS_G12V FOXP1 90 27 50-65yrs -1.02 -2.33 0.15 565.19 1.01 853 89 26 1 FALSE 1.00
colorectal cancer KRAS_G12V FOXP1 59 14 >65yrs -1.02 -2.42 0.20 524.50 1.01 577 58 13 1 FALSE 0.93
colorectal cancer KRAS_G12V FOXP1 204 70 Age:overall -1.03 -2.31 0.12 537.32 1.01 2018 201 67 3 FALSE 1.00
colorectal cancer KRAS_G12V NOTCH2 86 24 50-65yrs -2.12 -4.89 -0.10 320.58 1.01 831 85 23 1 TRUE 1.00
colorectal cancer KRAS_G12V NOTCH2 55 31 >65yrs -2.58 -6.16 -0.27 888.85 1.00 553 55 31 0 TRUE 1.06
non-small cell lung cancer KRAS_G12V NOTCH2 62 43 50-65yrs -0.26 -1.91 0.77 357.40 1.00 1214 61 42 1 TRUE 0.17
non-small cell lung cancer KRAS_G12V NOTCH2 100 67 >65yrs -0.15 -1.35 0.77 270.86 1.00 1960 96 63 4 TRUE 0.11
uterine cancer KRAS_G12V NOTCH2 32 28 50-65yrs -4.84 -11.00 -0.69 1194.34 1.00 436 32 28 0 TRUE 1.06
uterine cancer KRAS_G12V NOTCH2 17 20 >65yrs -4.83 -11.15 -0.54 1223.45 1.00 417 17 20 0 TRUE 1.05
colorectal cancer KRAS_G12V NOTCH2 141 55 Age:overall -2.29 -5.09 0.02 414.64 1.01 1384 140 54 1 TRUE 1.02
non-small cell lung cancer KRAS_G12V NOTCH2 162 110 Age:overall -0.20 -1.70 0.80 347.58 1.00 3174 157 105 5 TRUE 0.13
uterine cancer KRAS_G12V NOTCH2 49 48 Age:overall -4.76 -11.00 -0.48 1172.14 1.00 853 49 48 0 TRUE 1.06
non-small cell lung cancer KRAS_G12V DDR2 62 39 50-65yrs 0.33 -0.71 1.28 1049.78 1.00 1218 58 35 4 TRUE 0.29
non-small cell lung cancer KRAS_G12V DDR2 100 56 >65yrs 0.12 -1.00 0.97 1157.61 1.00 1974 98 54 2 TRUE 0.09
uterine cancer KRAS_G12V DDR2 34 30 50-65yrs -4.99 -12.15 -0.48 804.92 1.00 458 34 30 0 TRUE 0.96
uterine cancer KRAS_G12V DDR2 17 18 >65yrs -4.89 -12.17 -0.21 883.30 1.00 444 17 18 0 TRUE 0.95
non-small cell lung cancer KRAS_G12V DDR2 162 95 Age:overall 0.23 -0.88 1.22 964.94 1.00 3192 156 89 6 TRUE 0.18
uterine cancer KRAS_G12V DDR2 51 48 Age:overall -4.81 -11.63 -0.21 841.78 1.00 902 51 48 0 TRUE 0.98
colorectal cancer KRAS_G12V TGFBR2 42 18 40-50yrs -1.16 -3.26 0.01 1119.96 1.00 391 42 18 0 TRUE 0.78
colorectal cancer KRAS_G12V TGFBR2 91 42 50-65yrs -0.60 -1.71 0.43 402.02 1.01 842 86 37 5 TRUE 0.54
colorectal cancer KRAS_G12V TGFBR2 59 46 >65yrs -1.27 -3.53 -0.10 1015.29 1.00 546 59 46 0 TRUE 0.82
non-small cell lung cancer KRAS_G12V TGFBR2 62 28 50-65yrs -0.37 -2.26 0.86 51.36 1.05 1229 61 27 1 TRUE 0.18
non-small cell lung cancer KRAS_G12V TGFBR2 100 26 >65yrs -0.39 -2.27 0.90 62.35 1.05 2004 99 25 1 TRUE 0.18
colorectal cancer KRAS_G12V TGFBR2 192 106 Age:overall -1.01 -2.66 0.04 910.63 1.00 1779 187 101 5 TRUE 0.90
non-small cell lung cancer KRAS_G12V TGFBR2 162 54 Age:overall -0.37 -2.23 1.02 60.62 1.05 3233 160 52 2 TRUE 0.16
colorectal cancer KRAS_G12V SMO 45 14 40-50yrs -0.54 -1.62 0.39 373.57 1.01 428 44 13 1 TRUE 0.51
colorectal cancer KRAS_G12V SMO 106 29 50-65yrs -0.55 -1.67 0.37 340.93 1.01 944 104 27 2 TRUE 0.53
colorectal cancer KRAS_G12V SMO 62 21 >65yrs -0.55 -1.62 0.39 330.75 1.02 640 61 20 1 TRUE 0.53
non-small cell lung cancer KRAS_G12V SMO 63 25 50-65yrs -1.75 -4.61 0.00 647.70 1.01 1287 63 25 0 TRUE 0.89
non-small cell lung cancer KRAS_G12V SMO 106 45 >65yrs -1.63 -4.12 0.10 570.36 1.02 2034 105 44 1 TRUE 0.94
uterine cancer KRAS_G12V SMO 39 21 50-65yrs -4.88 -11.56 -0.49 1156.01 1.00 519 39 21 0 TRUE 1.01
uterine cancer KRAS_G12V SMO 19 23 >65yrs -4.87 -11.52 -0.38 1233.57 1.00 482 19 23 0 TRUE 1.02
colorectal cancer KRAS_G12V SMO 213 64 Age:overall -0.54 -1.61 0.38 327.87 1.01 2012 209 60 4 TRUE 0.54
non-small cell lung cancer KRAS_G12V SMO 169 70 Age:overall -1.68 -4.28 0.16 637.00 1.01 3321 168 69 1 TRUE 0.93
uterine cancer KRAS_G12V SMO 58 44 Age:overall -4.74 -11.27 -0.28 1260.74 1.00 1001 58 44 0 TRUE 0.99
colorectal cancer KRAS_G12V RPS6KA4 86 28 50-65yrs -1.81 -4.45 -0.16 289.94 1.02 827 85 27 1 FALSE 1.05
colorectal cancer KRAS_G12V RPS6KA4 55 16 >65yrs -1.97 -4.90 -0.15 305.88 1.03 563 55 16 0 FALSE 0.99
colorectal cancer KRAS_G12V RPS6KA4 141 44 Age:overall -1.87 -4.65 -0.12 404.29 1.02 1390 140 43 1 FALSE 1.01
colorectal cancer KRAS_G12V KMT2A 13 22 <40yrs -1.46 -2.81 -0.44 1218.84 1.00 188 13 22 0 FALSE 1.78
colorectal cancer KRAS_G12V KMT2A 42 22 40-50yrs -1.41 -2.67 -0.34 1063.32 1.00 394 41 21 1 FALSE 1.75
colorectal cancer KRAS_G12V KMT2A 90 53 50-65yrs -1.48 -2.74 -0.52 973.31 1.00 836 89 52 1 FALSE 2.00
colorectal cancer KRAS_G12V KMT2A 59 51 >65yrs -1.40 -2.63 -0.43 1051.72 1.00 552 57 49 2 FALSE 1.84
non-small cell lung cancer KRAS_G12V KMT2A 62 33 50-65yrs -0.03 -1.29 0.91 761.89 1.00 1221 61 32 1 FALSE 0.02
non-small cell lung cancer KRAS_G12V KMT2A 100 75 >65yrs 0.16 -0.95 0.96 628.37 1.00 1964 95 70 5 FALSE 0.13
uterine cancer KRAS_G12V KMT2A 7 13 40-50yrs -1.53 -4.24 0.14 963.13 1.00 76 7 13 0 FALSE 0.76
uterine cancer KRAS_G12V KMT2A 34 50 50-65yrs -1.74 -4.54 -0.14 1049.79 1.00 445 34 50 0 FALSE 0.86
uterine cancer KRAS_G12V KMT2A 17 36 >65yrs -0.96 -2.94 0.88 880.81 1.00 436 15 34 2 FALSE 0.52
colorectal cancer KRAS_G12V KMT2A 204 148 Age:overall -1.44 -2.68 -0.48 1126.73 1.00 1970 200 144 4 FALSE 1.97
non-small cell lung cancer KRAS_G12V KMT2A 162 108 Age:overall 0.07 -1.21 1.05 897.58 1.00 3185 156 102 6 FALSE 0.04
uterine cancer KRAS_G12V KMT2A 58 99 Age:overall -1.39 -3.48 0.13 793.83 1.00 957 56 97 2 FALSE 0.87
colorectal cancer KRAS_G12V JAK3 106 28 50-65yrs -5.53 -12.61 -1.30 466.78 1.00 941 106 28 0 TRUE 1.29
colorectal cancer KRAS_G12V JAK3 62 22 >65yrs -5.51 -12.76 -1.15 461.55 1.01 640 62 22 0 TRUE 1.27
non-small cell lung cancer KRAS_G12V JAK3 64 33 50-65yrs 0.46 -0.56 1.41 445.71 1.00 1281 61 30 3 TRUE 0.43
non-small cell lung cancer KRAS_G12V JAK3 106 48 >65yrs 0.38 -0.66 1.35 376.49 1.00 2033 103 45 3 TRUE 0.34
colorectal cancer KRAS_G12V JAK3 168 50 Age:overall -5.48 -12.56 -1.16 452.94 1.00 1581 168 50 0 TRUE 1.29
non-small cell lung cancer KRAS_G12V JAK3 170 81 Age:overall 0.43 -0.61 1.53 484.83 1.00 3314 164 75 6 TRUE 0.36
non-small cell lung cancer KRAS_G12V PAK7 62 45 50-65yrs 0.59 -0.23 1.29 1486.98 1.00 1208 59 42 3 FALSE 0.87
non-small cell lung cancer KRAS_G12V PAK7 100 81 >65yrs 0.67 -0.03 1.29 1461.97 1.00 1954 92 73 8 FALSE 1.27
non-small cell lung cancer KRAS_G12V PAK7 162 126 Age:overall 0.63 -0.16 1.33 1540.77 1.00 3162 151 115 11 FALSE 0.90
non-small cell lung cancer KRAS_G12V STAG2 63 38 50-65yrs 0.31 -0.63 1.23 491.60 1.01 1223 59 34 4 TRUE 0.28
non-small cell lung cancer KRAS_G12V STAG2 100 61 >65yrs 0.09 -1.02 0.91 313.72 1.02 1970 98 59 2 TRUE 0.07
uterine cancer KRAS_G12V STAG2 7 13 40-50yrs -2.20 -5.29 -0.05 1384.07 1.00 77 7 13 0 TRUE 0.96
uterine cancer KRAS_G12V STAG2 34 42 50-65yrs -2.03 -4.92 -0.15 1398.43 1.00 452 33 41 1 TRUE 1.02
uterine cancer KRAS_G12V STAG2 17 24 >65yrs -2.22 -5.51 -0.18 1256.91 1.00 438 17 24 0 TRUE 0.99
non-small cell lung cancer KRAS_G12V STAG2 163 99 Age:overall 0.20 -0.81 1.12 467.09 1.01 3193 157 93 6 TRUE 0.15
uterine cancer KRAS_G12V STAG2 58 79 Age:overall -2.12 -5.21 -0.16 1359.00 1.00 967 57 78 1 TRUE 1.04
colorectal cancer KRAS_G12V BRCA2 13 26 <40yrs -1.27 -2.36 -0.30 1165.05 1.00 192 13 26 0 TRUE 1.74
colorectal cancer KRAS_G12V BRCA2 42 38 40-50yrs -1.09 -2.08 -0.13 1245.65 1.00 389 39 35 3 TRUE 1.55
colorectal cancer KRAS_G12V BRCA2 90 61 50-65yrs -1.16 -2.12 -0.27 1185.64 1.00 841 87 58 3 TRUE 1.86
colorectal cancer KRAS_G12V BRCA2 59 65 >65yrs -1.37 -2.55 -0.43 1353.75 1.00 537 59 65 0 TRUE 1.90
non-small cell lung cancer KRAS_G12V BRCA2 62 58 50-65yrs -0.25 -1.40 0.69 824.99 1.00 1201 59 55 3 TRUE 0.20
non-small cell lung cancer KRAS_G12V BRCA2 101 72 >65yrs -0.37 -1.52 0.56 613.87 1.00 1966 99 70 2 TRUE 0.30
uterine cancer KRAS_G12V BRCA2 7 28 40-50yrs -2.91 -6.26 -0.61 1357.73 1.00 71 7 28 0 TRUE 1.31
uterine cancer KRAS_G12V BRCA2 34 51 50-65yrs -2.99 -6.26 -0.84 1394.83 1.00 442 34 51 0 TRUE 1.48
uterine cancer KRAS_G12V BRCA2 17 43 >65yrs -2.18 -5.09 0.07 1424.68 1.00 432 16 42 1 TRUE 0.99
colorectal cancer KRAS_G12V BRCA2 204 190 Age:overall -1.22 -2.23 -0.36 1118.55 1.00 1959 198 184 6 TRUE 2.06
non-small cell lung cancer KRAS_G12V BRCA2 163 130 Age:overall -0.31 -1.53 0.70 760.59 1.00 3167 158 125 5 TRUE 0.22
uterine cancer KRAS_G12V BRCA2 58 134 Age:overall -2.68 -5.51 -0.53 1346.11 1.00 974 57 133 1 TRUE 1.42
colorectal cancer KRAS_G12V NOTCH3 13 22 <40yrs -1.05 -2.31 -0.02 1488.25 1.00 188 13 22 0 TRUE 1.13
colorectal cancer KRAS_G12V NOTCH3 43 28 40-50yrs -0.51 -1.56 0.68 1119.55 1.00 388 38 23 5 TRUE 0.44
colorectal cancer KRAS_G12V NOTCH3 90 71 50-65yrs -1.17 -2.29 -0.32 1264.88 1.00 823 89 70 1 TRUE 1.73
colorectal cancer KRAS_G12V NOTCH3 59 79 >65yrs -1.07 -2.12 -0.21 1488.49 1.00 530 57 77 2 TRUE 1.61
non-small cell lung cancer KRAS_G12V NOTCH3 62 44 50-65yrs -0.02 -1.28 0.86 1137.60 1.00 1213 61 43 1 TRUE 0.01
non-small cell lung cancer KRAS_G12V NOTCH3 100 78 >65yrs 0.22 -0.67 0.96 1343.87 1.00 1962 94 72 6 TRUE 0.22
uterine cancer KRAS_G12V NOTCH3 34 42 50-65yrs -1.15 -3.17 0.30 1451.00 1.00 448 33 41 1 TRUE 0.73
uterine cancer KRAS_G12V NOTCH3 17 41 >65yrs -1.00 -3.02 0.54 1410.75 1.00 426 16 40 1 TRUE 0.58
colorectal cancer KRAS_G12V NOTCH3 205 200 Age:overall -0.95 -1.90 -0.09 1498.83 1.00 1929 197 192 8 TRUE 1.48
non-small cell lung cancer KRAS_G12V NOTCH3 162 122 Age:overall 0.10 -0.97 1.03 1323.68 1.00 3175 155 115 7 TRUE 0.07
uterine cancer KRAS_G12V NOTCH3 51 83 Age:overall -1.07 -3.07 0.64 1419.00 1.00 874 49 81 2 TRUE 0.59
colorectal cancer KRAS_G12V NOTCH4 12 12 <40yrs -1.34 -2.89 -0.41 28.08 1.13 189 12 12 0 TRUE 1.29
colorectal cancer KRAS_G12V NOTCH4 41 19 40-50yrs -1.35 -2.90 -0.40 28.06 1.13 378 41 19 0 TRUE 1.28
colorectal cancer KRAS_G12V NOTCH4 86 43 50-65yrs -1.29 -2.81 -0.35 27.00 1.13 815 84 41 2 TRUE 1.28
colorectal cancer KRAS_G12V NOTCH4 55 48 >65yrs -1.34 -2.84 -0.41 25.60 1.14 539 54 47 1 TRUE 1.35
non-small cell lung cancer KRAS_G12V NOTCH4 62 49 50-65yrs 0.37 -0.43 1.11 679.26 1.00 1205 58 45 4 TRUE 0.46
non-small cell lung cancer KRAS_G12V NOTCH4 100 84 >65yrs 0.33 -0.46 1.02 765.87 1.00 1945 95 79 5 TRUE 0.42
uterine cancer KRAS_G12V NOTCH4 7 13 40-50yrs -1.36 -4.44 0.59 1483.79 1.00 67 7 13 0 TRUE 0.54
uterine cancer KRAS_G12V NOTCH4 32 29 50-65yrs -1.52 -4.78 0.26 1465.17 1.00 434 32 29 0 TRUE 0.65
uterine cancer KRAS_G12V NOTCH4 18 20 >65yrs -0.25 -2.33 1.47 1384.21 1.00 418 16 18 2 TRUE 0.10
colorectal cancer KRAS_G12V NOTCH4 194 122 Age:overall -1.33 -2.84 -0.40 24.07 1.14 1921 191 119 3 TRUE 1.36
non-small cell lung cancer KRAS_G12V NOTCH4 162 133 Age:overall 0.34 -0.50 1.09 712.76 1.00 3150 153 124 9 TRUE 0.38
uterine cancer KRAS_G12V NOTCH4 57 62 Age:overall -1.03 -3.49 0.70 1531.43 1.00 919 55 60 2 TRUE 0.48
colorectal cancer KRAS_G12V FGFR3 106 25 50-65yrs -1.12 -2.96 0.21 517.18 1.01 946 105 24 1 TRUE 0.77
colorectal cancer KRAS_G12V FGFR3 62 24 >65yrs -1.08 -3.01 0.33 457.41 1.01 638 61 23 1 TRUE 0.72
colorectal cancer KRAS_G12V FGFR3 168 49 Age:overall -1.08 -3.00 0.34 489.08 1.00 1584 166 47 2 TRUE 0.71
non-small cell lung cancer KRAS_G12V MAP3K13 62 21 50-65yrs 0.72 -0.86 1.67 970.49 1.00 1227 61 20 1 FALSE 0.60
non-small cell lung cancer KRAS_G12V MAP3K13 101 30 >65yrs 0.98 -0.06 1.89 776.68 1.00 1996 96 25 5 FALSE 1.39
non-small cell lung cancer KRAS_G12V MAP3K13 163 51 Age:overall 0.84 -0.45 1.80 1093.89 1.00 3223 157 45 6 FALSE 0.84
colorectal cancer KRAS_G12V IGF1R 13 11 <40yrs -1.01 -2.60 0.33 1620.18 1.00 197 12 10 1 TRUE 0.76
colorectal cancer KRAS_G12V IGF1R 42 11 40-50yrs -1.19 -2.79 0.09 1497.91 1.00 398 42 11 0 TRUE 0.96
colorectal cancer KRAS_G12V IGF1R 90 25 50-65yrs -1.00 -2.35 0.21 1498.24 1.00 857 88 23 2 TRUE 0.84
colorectal cancer KRAS_G12V IGF1R 59 33 >65yrs -1.24 -2.84 -0.02 1443.61 1.00 561 59 33 0 TRUE 1.06
non-small cell lung cancer KRAS_G12V IGF1R 62 29 50-65yrs -5.00 -11.86 -0.50 1033.83 1.00 1224 62 29 0 TRUE 1.04
non-small cell lung cancer KRAS_G12V IGF1R 100 23 >65yrs -4.97 -11.80 -0.54 1017.72 1.00 2006 100 23 0 TRUE 1.03
colorectal cancer KRAS_G12V IGF1R 204 80 Age:overall -1.11 -2.48 0.06 1537.31 1.00 2013 201 77 3 TRUE 1.01
non-small cell lung cancer KRAS_G12V IGF1R 162 52 Age:overall -4.88 -11.73 -0.46 1002.17 1.00 3230 162 52 0 TRUE 1.03
non-small cell lung cancer KRAS_G12V KEAP1 6 22 40-50yrs 0.22 -0.49 1.50 756.85 1.00 166 3 19 3 FALSE 0.18
non-small cell lung cancer KRAS_G12V KEAP1 62 203 50-65yrs 0.13 -0.44 0.70 446.43 1.00 1072 49 190 13 FALSE 0.18
non-small cell lung cancer KRAS_G12V KEAP1 100 312 >65yrs -0.15 -0.83 0.35 1005.55 1.00 1739 91 303 9 FALSE 0.21
non-small cell lung cancer KRAS_G12V KEAP1 168 537 Age:overall 0.07 -0.48 0.84 614.73 1.00 2977 143 512 25 FALSE 0.07
colorectal cancer KRAS_G12V KDM5C 90 24 50-65yrs -1.58 -4.42 0.11 1224.85 1.00 856 90 24 0 FALSE 0.69
colorectal cancer KRAS_G12V KDM5C 59 26 >65yrs -1.00 -2.94 0.48 1061.82 1.00 570 57 24 2 FALSE 0.60
non-small cell lung cancer KRAS_G12V KDM5C 62 43 50-65yrs 0.54 -0.39 1.32 1343.27 1.00 1217 58 39 4 FALSE 0.71
non-small cell lung cancer KRAS_G12V KDM5C 100 59 >65yrs 0.48 -0.45 1.22 1547.52 1.00 1975 96 55 4 FALSE 0.59
uterine cancer KRAS_G12V KDM5C 34 32 50-65yrs -1.43 -5.01 0.41 1186.15 1.00 456 34 32 0 FALSE 0.42
uterine cancer KRAS_G12V KDM5C 18 32 >65yrs -0.33 -2.12 1.29 1022.64 1.00 436 16 30 2 FALSE 0.15
colorectal cancer KRAS_G12V KDM5C 149 50 Age:overall -1.24 -3.65 0.48 1282.83 1.00 1426 147 48 2 FALSE 0.61
non-small cell lung cancer KRAS_G12V KDM5C 162 102 Age:overall 0.51 -0.52 1.32 1490.46 1.00 3192 154 94 8 FALSE 0.56
uterine cancer KRAS_G12V KDM5C 52 64 Age:overall -0.83 -3.49 1.18 1272.77 1.00 892 50 62 2 FALSE 0.32
non-small cell lung cancer KRAS_G12V CDKN2A 6 18 40-50yrs -0.08 -0.98 0.66 1429.93 1.00 180 6 18 0 TRUE 0.07
non-small cell lung cancer KRAS_G12V CDKN2A 63 114 50-65yrs -0.04 -0.76 0.61 1420.48 1.00 1210 58 109 5 TRUE 0.04
non-small cell lung cancer KRAS_G12V CDKN2A 107 141 >65yrs 0.00 -0.65 0.60 1561.97 1.00 1949 99 133 8 TRUE 0.00
pancreatic cancer KRAS_G12V CDKN2A 19 11 40-50yrs 0.53 -0.38 1.60 1513.72 1.00 100 15 7 4 TRUE 0.54
pancreatic cancer KRAS_G12V CDKN2A 164 104 50-65yrs 0.28 -0.15 0.71 1376.54 1.00 404 133 73 31 TRUE 0.68
pancreatic cancer KRAS_G12V CDKN2A 222 175 >65yrs 0.27 -0.11 0.61 1454.31 1.00 452 167 120 55 TRUE 0.88
non-small cell lung cancer KRAS_G12V CDKN2A 176 273 Age:overall -0.04 -0.73 0.60 1589.19 1.00 3339 163 260 13 TRUE 0.05
pancreatic cancer KRAS_G12V CDKN2A 405 290 Age:overall 0.37 -0.32 1.19 1349.40 1.00 956 315 200 90 TRUE 0.48
colorectal cancer KRAS_G12V EPHB1 13 13 <40yrs -1.46 -3.33 0.00 875.67 1.00 192 13 13 0 FALSE 1.05
colorectal cancer KRAS_G12V EPHB1 90 31 50-65yrs -1.46 -3.24 -0.05 690.19 1.01 848 89 30 1 FALSE 1.16
colorectal cancer KRAS_G12V EPHB1 59 28 >65yrs -1.43 -3.27 -0.03 775.39 1.00 565 58 27 1 FALSE 1.08
non-small cell lung cancer KRAS_G12V EPHB1 62 54 50-65yrs -0.52 -1.43 0.56 21.86 1.10 1211 59 51 3 FALSE 0.51
non-small cell lung cancer KRAS_G12V EPHB1 100 99 >65yrs -0.66 -1.55 0.24 48.83 1.05 1936 98 97 2 FALSE 0.80
colorectal cancer KRAS_G12V EPHB1 162 72 Age:overall -1.44 -3.27 -0.07 749.84 1.01 1605 160 70 2 FALSE 1.12
non-small cell lung cancer KRAS_G12V EPHB1 162 153 Age:overall -0.59 -1.57 0.44 41.35 1.06 3147 157 148 5 FALSE 0.58
colorectal cancer KRAS_G12V IRS2 14 13 <40yrs -1.09 -2.47 0.10 936.95 1.00 193 12 11 2 FALSE 1.00
colorectal cancer KRAS_G12V IRS2 42 19 40-50yrs -1.15 -2.50 -0.08 1083.10 1.00 392 41 18 1 FALSE 1.15
colorectal cancer KRAS_G12V IRS2 90 30 50-65yrs -1.19 -2.54 -0.13 1062.29 1.00 851 90 30 0 FALSE 1.25
colorectal cancer KRAS_G12V IRS2 59 25 >65yrs -1.20 -2.58 -0.10 1211.05 1.00 568 59 25 0 FALSE 1.21
non-small cell lung cancer KRAS_G12V IRS2 62 25 50-65yrs 0.27 -0.93 1.29 1199.06 1.00 1230 60 23 2 FALSE 0.21
non-small cell lung cancer KRAS_G12V IRS2 100 55 >65yrs 0.21 -0.90 1.12 1086.09 1.00 1979 97 52 3 FALSE 0.17
uterine cancer KRAS_G12V IRS2 34 32 50-65yrs -0.91 -2.84 0.52 624.45 1.00 452 33 31 1 FALSE 0.52
uterine cancer KRAS_G12V IRS2 17 34 >65yrs -0.83 -2.91 0.77 633.81 1.00 432 16 33 1 FALSE 0.42
colorectal cancer KRAS_G12V IRS2 205 87 Age:overall -1.16 -2.49 -0.07 1054.85 1.00 2004 202 84 3 FALSE 1.19
non-small cell lung cancer KRAS_G12V IRS2 162 80 Age:overall 0.23 -1.03 1.27 1222.10 1.00 3209 157 75 5 FALSE 0.17
uterine cancer KRAS_G12V IRS2 51 66 Age:overall -0.86 -2.99 0.92 769.99 1.00 884 49 64 2 FALSE 0.41
colorectal cancer KRAS_G12V FANCA 13 11 <40yrs -0.43 -1.64 0.80 1230.07 1.00 194 12 10 1 TRUE 0.30
colorectal cancer KRAS_G12V FANCA 42 11 40-50yrs -0.26 -1.50 1.10 905.36 1.00 401 39 8 3 TRUE 0.16
colorectal cancer KRAS_G12V FANCA 90 31 50-65yrs -0.70 -2.10 0.41 1065.26 1.00 852 90 31 0 TRUE 0.55
colorectal cancer KRAS_G12V FANCA 59 12 >65yrs -0.61 -1.96 0.52 1125.29 1.00 578 59 12 0 TRUE 0.47
non-small cell lung cancer KRAS_G12V FANCA 62 29 50-65yrs 0.14 -1.16 1.25 1331.47 1.00 1226 60 27 2 TRUE 0.09
non-small cell lung cancer KRAS_G12V FANCA 100 36 >65yrs 0.11 -1.14 1.12 1266.22 1.00 1996 98 34 2 TRUE 0.07
colorectal cancer KRAS_G12V FANCA 204 65 Age:overall -0.50 -1.64 0.58 1223.09 1.00 2025 200 61 4 TRUE 0.41
non-small cell lung cancer KRAS_G12V FANCA 162 65 Age:overall 0.13 -1.19 1.28 1293.78 1.00 3222 158 61 4 TRUE 0.08
non-small cell lung cancer KRAS_G12V IL7R 62 38 50-65yrs -0.54 -2.05 0.61 690.09 1.00 1221 61 37 1 FALSE 0.38
non-small cell lung cancer KRAS_G12V IL7R 100 49 >65yrs -0.49 -1.85 0.60 606.26 1.00 1985 98 47 2 FALSE 0.36
non-small cell lung cancer KRAS_G12V IL7R 162 87 Age:overall -0.52 -2.04 0.67 666.72 1.00 3206 159 84 3 FALSE 0.35
uterine cancer KRAS_G12V PPP2R1A 34 54 50-65yrs 0.20 -0.79 1.11 1633.04 1.00 432 29 49 5 FALSE 0.17
uterine cancer KRAS_G12V PPP2R1A 17 100 >65yrs -0.16 -1.30 0.86 1538.71 1.00 371 14 97 3 FALSE 0.11
uterine cancer KRAS_G12V PPP2R1A 51 154 Age:overall 0.02 -1.53 1.60 1234.85 1.00 803 43 146 8 FALSE 0.01
colorectal cancer KRAS_G12V PIK3CB 41 21 40-50yrs -1.94 -4.50 -0.32 475.25 1.01 380 40 20 1 FALSE 1.17
colorectal cancer KRAS_G12V PIK3CB 86 17 50-65yrs -2.12 -5.05 -0.46 210.09 1.02 841 86 17 0 FALSE 1.19
colorectal cancer KRAS_G12V PIK3CB 55 22 >65yrs -2.10 -5.02 -0.37 250.56 1.02 559 55 22 0 FALSE 1.17
colorectal cancer KRAS_G12V PIK3CB 182 60 Age:overall -2.06 -4.63 -0.48 332.95 1.01 1780 181 59 1 FALSE 1.25
colorectal cancer KRAS_G12V ERBB3 13 13 <40yrs -0.71 -1.79 0.28 1399.22 1.00 194 12 12 1 TRUE 0.75
colorectal cancer KRAS_G12V ERBB3 42 14 40-50yrs -0.76 -1.90 0.21 1331.55 1.00 397 41 13 1 TRUE 0.83
colorectal cancer KRAS_G12V ERBB3 90 48 50-65yrs -0.85 -1.90 0.02 1417.46 1.00 834 89 47 1 TRUE 1.10
colorectal cancer KRAS_G12V ERBB3 59 47 >65yrs -0.71 -1.78 0.16 1399.28 1.00 553 56 44 3 TRUE 0.85
uterine cancer KRAS_G12V ERBB3 34 45 50-65yrs -0.48 -2.01 0.71 1345.49 1.00 442 32 43 2 TRUE 0.31
uterine cancer KRAS_G12V ERBB3 17 24 >65yrs -0.33 -2.15 1.30 1520.30 1.00 434 16 23 1 TRUE 0.15
colorectal cancer KRAS_G12V ERBB3 204 122 Age:overall -0.75 -1.76 0.08 1275.31 1.00 1978 198 116 6 TRUE 0.98
uterine cancer KRAS_G12V ERBB3 51 69 Age:overall -0.40 -2.29 1.36 1370.13 1.00 876 48 66 3 TRUE 0.17
colorectal cancer KRAS_G12V SMAD4 13 33 <40yrs 0.33 -0.11 0.76 1367.08 1.00 194 12 32 1 TRUE 0.93
colorectal cancer KRAS_G12V SMAD4 46 68 40-50yrs 0.40 0.03 0.83 1223.53 1.00 390 35 57 11 TRUE 1.28
colorectal cancer KRAS_G12V SMAD4 107 151 50-65yrs 0.34 -0.06 0.71 1327.89 1.00 840 91 135 16 TRUE 1.13
colorectal cancer KRAS_G12V SMAD4 64 108 >65yrs 0.39 0.02 0.79 1241.41 1.01 577 49 93 15 TRUE 1.35
non-small cell lung cancer KRAS_G12V SMAD4 63 45 50-65yrs -0.14 -1.30 0.80 1089.66 1.00 1271 61 43 2 TRUE 0.10
non-small cell lung cancer KRAS_G12V SMAD4 106 64 >65yrs -0.13 -1.29 0.78 948.71 1.00 2016 103 61 3 TRUE 0.09
pancreatic cancer KRAS_G12V SMAD4 19 18 40-50yrs 0.18 -0.36 0.92 683.09 1.01 94 14 13 5 TRUE 0.23
pancreatic cancer KRAS_G12V SMAD4 162 113 50-65yrs 0.11 -0.27 0.47 459.19 1.01 392 131 82 31 TRUE 0.23
pancreatic cancer KRAS_G12V SMAD4 220 139 >65yrs 0.05 -0.33 0.39 508.49 1.00 467 182 101 38 TRUE 0.10
colorectal cancer KRAS_G12V SMAD4 230 360 Age:overall 0.36 0.00 0.74 1259.99 1.00 2001 187 317 43 TRUE 1.29
non-small cell lung cancer KRAS_G12V SMAD4 169 109 Age:overall -0.13 -1.31 0.89 1192.54 1.00 3287 164 104 5 TRUE 0.09
pancreatic cancer KRAS_G12V SMAD4 401 270 Age:overall 0.12 -0.35 0.70 534.11 1.00 953 327 196 74 TRUE 0.18
colorectal cancer KRAS_G12V ATM 13 24 <40yrs -0.18 -1.02 0.54 1344.42 1.00 209 12 23 1 TRUE 0.19
colorectal cancer KRAS_G12V ATM 45 33 40-50yrs -0.29 -1.13 0.38 1419.05 1.00 416 44 32 1 TRUE 0.35
colorectal cancer KRAS_G12V ATM 109 87 50-65yrs -0.02 -0.62 0.56 1350.44 1.00 907 98 76 11 TRUE 0.02
colorectal cancer KRAS_G12V ATM 62 87 >65yrs -0.18 -0.85 0.37 1454.93 1.00 597 56 81 6 TRUE 0.25
non-small cell lung cancer KRAS_G12V ATM 63 100 50-65yrs 0.61 0.05 1.13 1099.16 1.00 1229 54 91 9 TRUE 1.60
non-small cell lung cancer KRAS_G12V ATM 108 179 >65yrs 0.54 0.03 1.02 1001.90 1.00 1932 95 166 13 TRUE 1.50
uterine cancer KRAS_G12V ATM 8 24 40-50yrs -0.48 -1.82 0.70 1467.08 1.00 74 7 23 1 TRUE 0.34
uterine cancer KRAS_G12V ATM 40 84 50-65yrs -0.29 -1.19 0.52 1506.69 1.00 496 35 79 5 TRUE 0.29
uterine cancer KRAS_G12V ATM 19 50 >65yrs -0.53 -1.89 0.57 1413.92 1.00 467 18 49 1 TRUE 0.41
colorectal cancer KRAS_G12V ATM 229 231 Age:overall -0.17 -0.82 0.38 1164.28 1.00 2129 210 212 19 TRUE 0.24
non-small cell lung cancer KRAS_G12V ATM 171 279 Age:overall 0.58 0.02 1.11 1112.38 1.00 3161 149 257 22 TRUE 1.32
uterine cancer KRAS_G12V ATM 67 158 Age:overall -0.44 -1.57 0.59 1164.92 1.00 1037 60 151 7 TRUE 0.37
colorectal cancer KRAS_G12V RB1 45 15 40-50yrs -0.61 -2.08 0.79 736.58 1.01 430 42 12 3 TRUE 0.40
colorectal cancer KRAS_G12V RB1 106 20 50-65yrs -1.07 -2.89 0.22 1060.31 1.00 953 106 20 0 TRUE 0.76
colorectal cancer KRAS_G12V RB1 62 24 >65yrs -1.04 -2.68 0.21 1082.38 1.00 639 62 24 0 TRUE 0.67
non-small cell lung cancer KRAS_G12V RB1 63 82 50-65yrs -1.14 -2.39 -0.13 1140.69 1.00 1231 62 81 1 TRUE 1.34
non-small cell lung cancer KRAS_G12V RB1 106 131 >65yrs -1.09 -2.26 -0.17 950.42 1.00 1952 103 128 3 TRUE 1.39
uterine cancer KRAS_G12V RB1 39 48 50-65yrs -1.99 -6.04 0.02 1105.33 1.00 501 39 48 0 TRUE 0.67
uterine cancer KRAS_G12V RB1 20 35 >65yrs -0.51 -2.53 1.17 1292.97 1.00 478 18 33 2 TRUE 0.22
colorectal cancer KRAS_G12V RB1 213 59 Age:overall -0.92 -2.34 0.28 828.29 1.00 2022 210 56 3 TRUE 0.73
non-small cell lung cancer KRAS_G12V RB1 169 213 Age:overall -1.11 -2.27 -0.07 1141.33 1.00 3183 165 209 4 TRUE 1.20
uterine cancer KRAS_G12V RB1 59 83 Age:overall -1.21 -4.13 1.01 1163.13 1.00 979 57 81 2 TRUE 0.46
cancer of unknown primary KRAS_G12V KMT2D 27 40 50-65yrs -0.31 -1.55 0.79 1007.63 1.00 259 23 36 4 FALSE 0.23
cancer of unknown primary KRAS_G12V KMT2D 23 69 >65yrs -1.00 -2.70 0.16 1098.53 1.01 289 22 68 1 FALSE 0.76
colorectal cancer KRAS_G12V KMT2D 13 41 <40yrs -1.15 -2.19 -0.10 1381.87 1.00 180 11 39 2 FALSE 1.59
colorectal cancer KRAS_G12V KMT2D 42 52 40-50yrs -1.40 -2.44 -0.55 1681.24 1.00 375 41 51 1 FALSE 2.48
colorectal cancer KRAS_G12V KMT2D 90 122 50-65yrs -1.37 -2.21 -0.58 1564.15 1.00 798 87 119 3 FALSE 2.96
colorectal cancer KRAS_G12V KMT2D 59 173 >65yrs -1.31 -2.09 -0.61 1543.37 1.00 502 54 168 5 FALSE 3.29
non-small cell lung cancer KRAS_G12V KMT2D 62 130 50-65yrs -0.16 -0.84 0.47 1210.53 1.00 1151 56 124 6 FALSE 0.21
non-small cell lung cancer KRAS_G12V KMT2D 100 188 >65yrs -0.21 -0.85 0.37 1222.14 1.00 1871 93 181 7 FALSE 0.29
pancreatic cancer KRAS_G12V KMT2D 157 27 50-65yrs -0.70 -1.50 0.05 1291.41 1.00 438 153 23 4 FALSE 1.15
pancreatic cancer KRAS_G12V KMT2D 216 32 >65yrs -0.66 -1.42 0.00 1185.97 1.00 522 210 26 6 FALSE 1.14
uterine cancer KRAS_G12V KMT2D 7 26 40-50yrs -0.39 -1.37 0.64 747.12 1.00 69 5 24 2 FALSE 0.36
uterine cancer KRAS_G12V KMT2D 34 125 50-65yrs -0.61 -1.55 0.28 327.13 1.01 401 31 122 3 FALSE 0.75
uterine cancer KRAS_G12V KMT2D 17 108 >65yrs -0.40 -1.24 0.45 703.23 1.00 389 13 104 4 FALSE 0.44
cancer of unknown primary KRAS_G12V KMT2D 50 109 Age:overall -0.65 -2.35 0.86 1090.73 1.01 548 45 104 5 FALSE 0.39
colorectal cancer KRAS_G12V KMT2D 204 388 Age:overall -1.30 -2.12 -0.53 1479.48 1.00 1855 193 377 11 FALSE 3.01
non-small cell lung cancer KRAS_G12V KMT2D 162 318 Age:overall -0.19 -0.90 0.50 1183.83 1.00 3022 149 305 13 FALSE 0.22
pancreatic cancer KRAS_G12V KMT2D 373 59 Age:overall -0.67 -1.49 0.14 1416.46 1.00 960 363 49 10 FALSE 0.91
uterine cancer KRAS_G12V KMT2D 58 259 Age:overall -0.46 -1.35 0.43 591.27 1.00 859 49 250 9 FALSE 0.52
colorectal cancer KRAS_G12V TSC2 13 14 <40yrs -1.40 -3.01 -0.17 845.40 1.00 193 12 13 1 TRUE 1.30
colorectal cancer KRAS_G12V TSC2 42 19 40-50yrs -1.41 -2.83 -0.24 760.87 1.00 392 41 18 1 TRUE 1.41
colorectal cancer KRAS_G12V TSC2 90 36 50-65yrs -1.48 -3.04 -0.38 724.64 1.00 848 89 35 1 TRUE 1.51
colorectal cancer KRAS_G12V TSC2 59 46 >65yrs -1.55 -3.13 -0.44 654.87 1.00 555 59 46 0 TRUE 1.64
non-small cell lung cancer KRAS_G12V TSC2 62 23 50-65yrs 0.43 -0.71 1.53 463.45 1.00 1234 60 21 2 TRUE 0.36
non-small cell lung cancer KRAS_G12V TSC2 100 44 >65yrs 0.40 -0.70 1.40 467.46 1.01 1989 97 41 3 TRUE 0.37
uterine cancer KRAS_G12V TSC2 34 33 50-65yrs -0.91 -2.93 0.50 1164.42 1.00 455 33 32 1 TRUE 0.53
uterine cancer KRAS_G12V TSC2 17 34 >65yrs -0.79 -2.91 0.71 1101.75 1.00 431 16 33 1 TRUE 0.43
colorectal cancer KRAS_G12V TSC2 204 115 Age:overall -1.46 -2.93 -0.41 654.85 1.00 1988 201 112 3 TRUE 1.59
non-small cell lung cancer KRAS_G12V TSC2 162 67 Age:overall 0.41 -0.82 1.52 483.26 1.01 3223 157 62 5 TRUE 0.33
uterine cancer KRAS_G12V TSC2 51 67 Age:overall -0.83 -3.15 0.82 1234.88 1.00 886 49 65 2 TRUE 0.39
colorectal cancer KRAS_G12V APC 20 246 <40yrs 0.06 -0.28 0.38 821.63 1.01 84 5 231 15 TRUE 0.14
colorectal cancer KRAS_G12V APC 56 494 40-50yrs 0.07 -0.25 0.37 602.76 1.01 153 16 454 40 TRUE 0.20
colorectal cancer KRAS_G12V APC 146 1094 50-65yrs 0.13 -0.13 0.45 680.94 1.01 337 33 981 113 TRUE 0.42
colorectal cancer KRAS_G12V APC 89 704 >65yrs 0.11 -0.16 0.43 881.38 1.00 242 21 636 68 TRUE 0.34
non-small cell lung cancer KRAS_G12V APC 63 60 50-65yrs -0.60 -1.77 0.49 584.12 1.00 1257 60 57 3 TRUE 0.53
non-small cell lung cancer KRAS_G12V APC 106 87 >65yrs -0.88 -2.23 0.07 673.45 1.00 1996 105 86 1 TRUE 0.83
uterine cancer KRAS_G12V APC 8 30 40-50yrs -2.32 -5.89 -0.28 1592.98 1.00 76 8 30 0 TRUE 0.97
uterine cancer KRAS_G12V APC 39 45 50-65yrs -2.42 -6.11 -0.46 1478.50 1.00 512 39 45 0 TRUE 1.02
uterine cancer KRAS_G12V APC 19 42 >65yrs -0.82 -2.95 0.87 1455.92 1.00 477 17 40 2 TRUE 0.39
colorectal cancer KRAS_G12V APC 311 2538 Age:overall 0.09 -0.18 0.39 849.23 1.01 816 75 2302 236 TRUE 0.28
non-small cell lung cancer KRAS_G12V APC 169 147 Age:overall -0.73 -2.04 0.33 832.61 1.00 3253 165 143 4 TRUE 0.62
uterine cancer KRAS_G12V APC 66 117 Age:overall -1.81 -4.62 0.06 1530.68 1.00 1065 64 115 2 TRUE 0.91
colorectal cancer KRAS_G12V ERBB2 13 13 <40yrs -1.08 -2.29 -0.03 1006.26 1.00 210 13 13 0 TRUE 1.24
colorectal cancer KRAS_G12V ERBB2 45 13 40-50yrs -0.97 -2.12 0.17 877.26 1.00 429 43 11 2 TRUE 1.02
colorectal cancer KRAS_G12V ERBB2 106 49 50-65yrs -1.11 -2.18 -0.13 905.27 1.00 926 105 48 1 TRUE 1.41
colorectal cancer KRAS_G12V ERBB2 62 29 >65yrs -1.05 -2.16 -0.02 901.24 1.00 633 61 28 1 TRUE 1.29
non-small cell lung cancer KRAS_G12V ERBB2 63 53 50-65yrs -2.37 -5.47 -0.50 467.35 1.01 1259 63 53 0 TRUE 1.07
non-small cell lung cancer KRAS_G12V ERBB2 106 68 >65yrs -2.22 -5.08 -0.48 408.46 1.00 2013 105 67 1 TRUE 1.18
uterine cancer KRAS_G12V ERBB2 39 36 50-65yrs -5.09 -12.11 -0.78 1274.55 1.00 506 39 36 0 TRUE 1.05
uterine cancer KRAS_G12V ERBB2 19 14 >65yrs -5.02 -12.49 -0.38 1340.56 1.00 488 19 14 0 TRUE 0.95
colorectal cancer KRAS_G12V ERBB2 226 104 Age:overall -1.05 -2.10 -0.03 853.25 1.00 2198 222 100 4 TRUE 1.32
non-small cell lung cancer KRAS_G12V ERBB2 169 121 Age:overall -2.27 -5.17 -0.47 349.10 1.01 3272 168 120 1 TRUE 1.17
uterine cancer KRAS_G12V ERBB2 58 50 Age:overall -4.85 -11.75 -0.24 1361.89 1.00 994 58 50 0 TRUE 0.97
colorectal cancer KRAS_G12V JAK1 13 16 <40yrs -1.59 -3.55 -0.03 1470.56 1.00 195 13 16 0 TRUE 1.14
colorectal cancer KRAS_G12V JAK1 42 13 40-50yrs -1.44 -3.29 0.10 1355.89 1.00 399 41 12 1 TRUE 1.02
colorectal cancer KRAS_G12V JAK1 90 20 50-65yrs -1.64 -3.50 -0.14 1385.90 1.00 859 90 20 0 TRUE 1.23
colorectal cancer KRAS_G12V JAK1 59 26 >65yrs -1.50 -3.25 -0.08 1369.17 1.00 568 58 25 1 TRUE 1.16
non-small cell lung cancer KRAS_G12V JAK1 62 15 50-65yrs -0.41 -2.28 1.15 724.38 1.00 1239 61 14 1 TRUE 0.20
non-small cell lung cancer KRAS_G12V JAK1 100 34 >65yrs -0.48 -2.31 0.88 736.78 1.00 1998 99 33 1 TRUE 0.25
uterine cancer KRAS_G12V JAK1 7 19 40-50yrs -0.02 -1.18 1.12 1289.91 1.00 71 5 17 2 TRUE 0.01
uterine cancer KRAS_G12V JAK1 35 69 50-65yrs -0.15 -1.12 0.72 1220.45 1.00 435 31 65 4 TRUE 0.13
uterine cancer KRAS_G12V JAK1 17 51 >65yrs -0.29 -1.58 0.70 1315.53 1.00 420 16 50 1 TRUE 0.21
colorectal cancer KRAS_G12V JAK1 204 75 Age:overall -1.54 -3.32 -0.11 1472.92 1.00 2021 202 73 2 TRUE 1.24
non-small cell lung cancer KRAS_G12V JAK1 162 49 Age:overall -0.45 -2.31 1.06 930.82 1.00 3237 160 47 2 TRUE 0.22
uterine cancer KRAS_G12V JAK1 59 139 Age:overall -0.16 -1.26 0.87 1404.44 1.00 926 52 132 7 TRUE 0.12
uterine cancer KRAS_G12V CCND1 34 32 50-65yrs 0.08 -1.33 1.18 1337.56 1.00 449 32 30 2 TRUE 0.05
uterine cancer KRAS_G12V CCND1 17 27 >65yrs 0.32 -1.13 1.61 1407.11 1.00 432 15 25 2 TRUE 0.19
uterine cancer KRAS_G12V CCND1 51 59 Age:overall 0.18 -1.40 1.60 1515.12 1.00 881 47 55 4 TRUE 0.09
colorectal cancer KRAS_G12V ARID2 42 21 40-50yrs -0.70 -1.85 0.28 1285.42 1.00 390 42 21 0 FALSE 0.71
colorectal cancer KRAS_G12V ARID2 91 36 50-65yrs -0.61 -1.59 0.26 1316.90 1.00 848 89 34 2 FALSE 0.69
colorectal cancer KRAS_G12V ARID2 59 44 >65yrs -0.49 -1.45 0.42 1306.19 1.00 554 55 40 4 FALSE 0.52
non-small cell lung cancer KRAS_G12V ARID2 62 71 50-65yrs -0.88 -2.02 0.19 104.00 1.02 1187 60 69 2 FALSE 0.85
non-small cell lung cancer KRAS_G12V ARID2 100 105 >65yrs -0.93 -2.09 0.16 106.62 1.02 1936 98 103 2 FALSE 0.94
uterine cancer KRAS_G12V ARID2 34 40 50-65yrs -5.25 -12.51 -0.88 1366.47 1.00 451 34 40 0 FALSE 1.04
uterine cancer KRAS_G12V ARID2 17 19 >65yrs -5.18 -12.78 -0.56 1402.78 1.00 441 17 19 0 FALSE 0.98
colorectal cancer KRAS_G12V ARID2 192 101 Age:overall -0.59 -1.54 0.33 1232.82 1.00 1792 186 95 6 FALSE 0.68
non-small cell lung cancer KRAS_G12V ARID2 162 176 Age:overall -0.90 -2.09 0.22 134.43 1.01 3123 158 172 4 FALSE 0.80
uterine cancer KRAS_G12V ARID2 51 59 Age:overall -5.07 -12.32 -0.49 1471.63 1.00 892 51 59 0 FALSE 0.98
colorectal cancer KRAS_G12V SOX17 41 11 40-50yrs -1.09 -2.79 0.33 1568.17 1.00 385 40 10 1 FALSE 0.76
colorectal cancer KRAS_G12V SOX17 86 32 50-65yrs -1.07 -2.62 0.21 1296.75 1.00 825 84 30 2 FALSE 0.89
colorectal cancer KRAS_G12V SOX17 55 47 >65yrs -1.59 -3.56 -0.27 1261.32 1.00 536 55 47 0 FALSE 1.19
non-small cell lung cancer KRAS_G12V SOX17 62 26 50-65yrs 0.19 -1.27 1.33 729.79 1.00 1223 61 25 1 FALSE 0.11
non-small cell lung cancer KRAS_G12V SOX17 100 32 >65yrs 0.35 -0.89 1.43 681.16 1.00 1993 97 29 3 FALSE 0.26
uterine cancer KRAS_G12V SOX17 32 24 50-65yrs 0.71 -0.66 1.90 935.97 1.00 441 28 20 4 FALSE 0.57
uterine cancer KRAS_G12V SOX17 17 22 >65yrs -0.36 -4.26 1.47 1170.73 1.00 412 17 22 0 FALSE 0.09
colorectal cancer KRAS_G12V SOX17 182 90 Age:overall -1.24 -2.86 0.01 1479.66 1.00 1746 179 87 3 FALSE 1.06
non-small cell lung cancer KRAS_G12V SOX17 162 58 Age:overall 0.26 -1.18 1.46 719.82 1.00 3216 158 54 4 FALSE 0.16
uterine cancer KRAS_G12V SOX17 49 46 Age:overall 0.22 -2.39 1.88 1450.91 1.00 853 45 42 4 FALSE 0.08
colorectal cancer KRAS_G12V MTOR 13 15 <40yrs -0.14 -0.87 0.50 676.95 1.01 194 12 14 1 TRUE 0.16
colorectal cancer KRAS_G12V MTOR 42 26 40-50yrs -0.13 -0.83 0.49 848.61 1.00 390 39 23 3 TRUE 0.16
colorectal cancer KRAS_G12V MTOR 90 54 50-65yrs -0.14 -0.85 0.46 654.20 1.00 835 85 49 5 TRUE 0.18
colorectal cancer KRAS_G12V MTOR 59 45 >65yrs -0.18 -0.91 0.44 633.15 1.01 553 57 43 2 TRUE 0.22
non-small cell lung cancer KRAS_G12V MTOR 62 39 50-65yrs -0.33 -1.59 0.75 389.52 1.00 1217 60 37 2 TRUE 0.24
non-small cell lung cancer KRAS_G12V MTOR 100 70 >65yrs -0.38 -1.59 0.67 365.69 1.01 1962 98 68 2 TRUE 0.30
uterine cancer KRAS_G12V MTOR 7 13 40-50yrs -0.84 -2.71 0.56 1580.47 1.00 74 7 13 0 TRUE 0.49
uterine cancer KRAS_G12V MTOR 35 35 50-65yrs -0.65 -2.11 0.54 1403.56 1.00 452 33 33 2 TRUE 0.48
uterine cancer KRAS_G12V MTOR 17 39 >65yrs -0.72 -2.28 0.59 1169.13 1.00 425 16 38 1 TRUE 0.47
colorectal cancer KRAS_G12V MTOR 204 140 Age:overall -0.15 -0.82 0.46 669.77 1.00 1972 193 129 11 TRUE 0.19
non-small cell lung cancer KRAS_G12V MTOR 162 109 Age:overall -0.34 -1.59 0.81 448.24 1.00 3179 158 105 4 TRUE 0.25
uterine cancer KRAS_G12V MTOR 59 87 Age:overall -0.73 -2.31 0.56 1515.73 1.00 951 56 84 3 TRUE 0.51
non-small cell lung cancer KRAS_G12V RFWD2 62 25 50-65yrs -4.74 -11.34 -0.80 370.06 1.00 1222 62 25 0 FALSE 1.05
non-small cell lung cancer KRAS_G12V RFWD2 100 31 >65yrs -4.77 -11.11 -0.73 325.10 1.01 1990 100 31 0 FALSE 1.08
non-small cell lung cancer KRAS_G12V RFWD2 162 56 Age:overall -4.70 -11.13 -0.65 324.56 1.01 3212 162 56 0 FALSE 1.05
colorectal cancer KRAS_G12V IRS1 41 17 40-50yrs -0.55 -1.60 0.48 1039.53 1.00 383 39 15 2 FALSE 0.52
colorectal cancer KRAS_G12V IRS1 86 34 50-65yrs -0.72 -1.99 0.27 994.14 1.00 825 86 34 0 FALSE 0.66
colorectal cancer KRAS_G12V IRS1 55 36 >65yrs -0.55 -1.58 0.45 962.60 1.00 548 52 33 3 FALSE 0.54
non-small cell lung cancer KRAS_G12V IRS1 62 28 50-65yrs -0.30 -1.85 0.85 1117.68 1.00 1220 61 27 1 FALSE 0.18
non-small cell lung cancer KRAS_G12V IRS1 100 42 >65yrs -0.26 -1.70 0.83 1084.26 1.00 1984 98 40 2 FALSE 0.16
colorectal cancer KRAS_G12V IRS1 182 87 Age:overall -0.60 -1.66 0.38 1025.88 1.00 1756 177 82 5 FALSE 0.60
non-small cell lung cancer KRAS_G12V IRS1 162 70 Age:overall -0.27 -1.81 0.89 1165.21 1.00 3204 159 67 3 FALSE 0.15
colorectal cancer KRAS_G12V NOTCH1 13 18 <40yrs -0.89 -2.07 0.44 1207.44 1.00 212 11 16 2 TRUE 0.85
colorectal cancer KRAS_G12V NOTCH1 46 27 40-50yrs -0.99 -2.02 0.02 1020.99 1.00 421 44 25 2 TRUE 1.22
colorectal cancer KRAS_G12V NOTCH1 106 55 50-65yrs -1.20 -2.23 -0.31 1038.64 1.00 925 105 54 1 TRUE 1.78
colorectal cancer KRAS_G12V NOTCH1 62 72 >65yrs -1.22 -2.26 -0.37 1016.58 1.00 606 61 71 1 TRUE 1.79
non-small cell lung cancer KRAS_G12V NOTCH1 63 45 50-65yrs -0.96 -3.22 0.39 164.90 1.01 1266 63 45 0 TRUE 0.48
non-small cell lung cancer KRAS_G12V NOTCH1 106 77 >65yrs -0.72 -2.19 0.42 131.64 1.02 2007 103 74 3 TRUE 0.56
uterine cancer KRAS_G12V NOTCH1 39 43 50-65yrs -2.37 -5.53 -0.26 1170.51 1.00 507 39 43 0 TRUE 1.04
uterine cancer KRAS_G12V NOTCH1 19 39 >65yrs -1.72 -4.37 0.34 1148.74 1.00 475 18 38 1 TRUE 0.79
colorectal cancer KRAS_G12V NOTCH1 227 172 Age:overall -1.07 -2.07 -0.18 996.17 1.00 2164 221 166 6 TRUE 1.58
non-small cell lung cancer KRAS_G12V NOTCH1 169 122 Age:overall -0.84 -2.53 0.41 162.83 1.02 3273 166 119 3 TRUE 0.49
uterine cancer KRAS_G12V NOTCH1 58 82 Age:overall -2.00 -5.04 0.15 1327.66 1.00 982 57 81 1 TRUE 0.84
colorectal cancer KRAS_G12V NTRK1 13 12 <40yrs -0.90 -2.83 0.58 1199.25 1.00 194 13 12 0 TRUE 0.51
colorectal cancer KRAS_G12V NTRK1 90 19 50-65yrs -0.80 -2.46 0.46 1153.32 1.00 859 89 18 1 TRUE 0.56
colorectal cancer KRAS_G12V NTRK1 59 26 >65yrs -0.67 -2.10 0.54 1207.71 1.00 568 57 24 2 TRUE 0.48
non-small cell lung cancer KRAS_G12V NTRK1 62 35 50-65yrs -1.75 -4.65 0.08 522.78 1.00 1221 61 34 1 TRUE 0.86
non-small cell lung cancer KRAS_G12V NTRK1 100 46 >65yrs -1.97 -5.05 -0.03 585.97 1.00 1982 100 46 0 TRUE 0.91
colorectal cancer KRAS_G12V NTRK1 162 57 Age:overall -0.80 -2.36 0.44 1146.30 1.00 1621 159 54 3 TRUE 0.57
non-small cell lung cancer KRAS_G12V NTRK1 162 81 Age:overall -1.85 -4.77 0.08 548.70 1.00 3203 161 80 1 TRUE 0.90
non-small cell lung cancer KRAS_G12V INPP4A 62 21 50-65yrs 0.08 -1.50 1.20 412.40 1.01 1227 61 20 1 FALSE 0.04
non-small cell lung cancer KRAS_G12V INPP4A 100 29 >65yrs 0.13 -1.31 1.26 363.28 1.01 1994 98 27 2 FALSE 0.07
uterine cancer KRAS_G12V INPP4A 32 27 50-65yrs -1.92 -5.66 0.20 1064.52 1.00 441 32 27 0 FALSE 0.61
uterine cancer KRAS_G12V INPP4A 17 25 >65yrs -1.29 -4.16 0.82 1147.34 1.00 419 16 24 1 FALSE 0.51
non-small cell lung cancer KRAS_G12V INPP4A 162 50 Age:overall 0.09 -1.47 1.25 387.01 1.01 3221 159 47 3 FALSE 0.05
uterine cancer KRAS_G12V INPP4A 49 52 Age:overall -1.54 -4.72 0.79 1281.89 1.00 860 48 51 1 FALSE 0.58
colorectal cancer KRAS_G12V CASP8 41 11 40-50yrs -5.66 -12.12 -1.41 1433.23 1.00 385 41 11 0 FALSE 1.38
colorectal cancer KRAS_G12V CASP8 86 30 50-65yrs -5.67 -12.18 -1.61 1519.31 1.00 828 86 30 0 FALSE 1.42
colorectal cancer KRAS_G12V CASP8 55 46 >65yrs -5.71 -12.21 -1.64 1435.12 1.00 539 55 46 0 FALSE 1.41
uterine cancer KRAS_G12V CASP8 32 28 50-65yrs -1.88 -5.47 0.28 1034.63 1.00 436 32 28 0 FALSE 0.70
uterine cancer KRAS_G12V CASP8 17 25 >65yrs -1.33 -4.09 0.80 973.44 1.00 415 16 24 1 FALSE 0.54
colorectal cancer KRAS_G12V CASP8 182 87 Age:overall -5.65 -12.13 -1.52 1479.83 1.00 1752 182 87 0 FALSE 1.42
uterine cancer KRAS_G12V CASP8 49 53 Age:overall -1.56 -4.53 0.73 1095.70 1.00 851 48 52 1 FALSE 0.63
colorectal cancer KRAS_G12V SETD2 13 20 <40yrs -2.69 -5.22 -0.78 1439.16 1.00 190 12 19 1 FALSE 1.71
colorectal cancer KRAS_G12V SETD2 42 15 40-50yrs -2.83 -5.57 -0.98 1456.90 1.00 396 42 15 0 FALSE 1.83
colorectal cancer KRAS_G12V SETD2 90 49 50-65yrs -2.85 -5.48 -1.04 1365.87 1.00 838 90 49 0 FALSE 1.98
colorectal cancer KRAS_G12V SETD2 59 29 >65yrs -2.84 -5.52 -1.02 1393.05 1.00 565 59 29 0 FALSE 1.84
non-small cell lung cancer KRAS_G12V SETD2 62 82 50-65yrs -0.67 -1.67 0.17 1151.71 1.00 1185 60 80 2 FALSE 0.79
non-small cell lung cancer KRAS_G12V SETD2 101 132 >65yrs -0.62 -1.53 0.15 1051.19 1.00 1921 97 128 4 FALSE 0.82
uterine cancer KRAS_G12V SETD2 7 14 40-50yrs -0.55 -2.20 0.84 1562.54 1.00 76 6 13 1 FALSE 0.32
uterine cancer KRAS_G12V SETD2 34 39 50-65yrs -0.75 -2.26 0.43 1537.25 1.00 450 33 38 1 FALSE 0.54
uterine cancer KRAS_G12V SETD2 17 31 >65yrs -0.60 -2.28 0.65 1500.56 1.00 433 16 30 1 FALSE 0.38
colorectal cancer KRAS_G12V SETD2 204 113 Age:overall -2.80 -5.40 -1.03 1384.67 1.00 1989 203 112 1 FALSE 1.94
non-small cell lung cancer KRAS_G12V SETD2 163 214 Age:overall -0.63 -1.63 0.23 1307.22 1.00 3106 157 208 6 FALSE 0.75
uterine cancer KRAS_G12V SETD2 58 84 Age:overall -0.64 -2.24 0.63 1616.34 1.00 959 55 81 3 FALSE 0.43
colorectal cancer KRAS_G12V PBRM1 42 21 40-50yrs -1.63 -3.44 -0.41 1114.99 1.00 391 41 20 1 TRUE 1.45
colorectal cancer KRAS_G12V PBRM1 90 32 50-65yrs -1.63 -3.44 -0.36 1191.05 1.00 852 89 31 1 TRUE 1.45
colorectal cancer KRAS_G12V PBRM1 59 31 >65yrs -1.67 -3.49 -0.42 1124.24 1.00 561 59 31 0 TRUE 1.48
non-small cell lung cancer KRAS_G12V PBRM1 62 37 50-65yrs -0.75 -3.19 0.50 991.06 1.00 1222 62 37 0 TRUE 0.36
non-small cell lung cancer KRAS_G12V PBRM1 102 71 >65yrs -0.32 -1.53 0.72 696.63 1.00 1967 98 67 4 TRUE 0.25
colorectal cancer KRAS_G12V PBRM1 191 84 Age:overall -1.65 -3.39 -0.42 1113.89 1.00 1804 189 82 2 TRUE 1.49
non-small cell lung cancer KRAS_G12V PBRM1 164 108 Age:overall -0.51 -2.24 0.69 1061.80 1.00 3189 160 104 4 TRUE 0.33
colorectal cancer KRAS_G12V EPHA3 13 14 <40yrs -0.09 -1.16 0.88 1500.43 1.00 194 12 13 1 FALSE 0.06
colorectal cancer KRAS_G12V EPHA3 42 15 40-50yrs -0.25 -1.44 0.62 979.66 1.00 396 42 15 0 FALSE 0.21
colorectal cancer KRAS_G12V EPHA3 90 39 50-65yrs -0.20 -1.10 0.57 1481.89 1.00 841 88 37 2 FALSE 0.20
colorectal cancer KRAS_G12V EPHA3 60 45 >65yrs 0.12 -0.66 0.89 1277.08 1.00 556 53 38 7 FALSE 0.11
non-small cell lung cancer KRAS_G12V EPHA3 6 11 40-50yrs 0.27 -0.57 1.13 1238.08 1.00 177 5 10 1 FALSE 0.29
non-small cell lung cancer KRAS_G12V EPHA3 62 103 50-65yrs 0.16 -0.55 0.78 1123.08 1.00 1166 58 99 4 FALSE 0.19
non-small cell lung cancer KRAS_G12V EPHA3 100 126 >65yrs 0.29 -0.34 0.89 1025.16 1.00 1918 91 117 9 FALSE 0.44
uterine cancer KRAS_G12V EPHA3 34 41 50-65yrs -5.13 -11.96 -0.79 1095.75 1.00 455 34 41 0 FALSE 1.09
uterine cancer KRAS_G12V EPHA3 17 21 >65yrs -5.11 -11.76 -0.67 1176.45 1.00 437 17 21 0 FALSE 1.05
colorectal cancer KRAS_G12V EPHA3 205 113 Age:overall -0.11 -0.98 0.62 1394.81 1.00 1987 195 103 10 FALSE 0.10
non-small cell lung cancer KRAS_G12V EPHA3 168 240 Age:overall 0.24 -0.46 0.88 1255.98 1.00 3261 154 226 14 FALSE 0.31
uterine cancer KRAS_G12V EPHA3 51 62 Age:overall -5.03 -11.61 -0.59 1110.69 1.00 892 51 62 0 FALSE 1.06
colorectal cancer KRAS_G12V KIT 45 13 40-50yrs -2.16 -4.61 -0.30 413.48 1.00 428 45 13 0 TRUE 1.20
colorectal cancer KRAS_G12V KIT 106 20 50-65yrs -2.17 -4.53 -0.35 429.17 1.00 950 106 20 0 TRUE 1.22
colorectal cancer KRAS_G12V KIT 62 17 >65yrs -2.10 -4.48 -0.23 362.48 1.00 644 61 16 1 TRUE 1.18
non-small cell lung cancer KRAS_G12V KIT 63 25 50-65yrs 0.18 -1.00 1.13 1314.57 1.00 1286 62 24 1 TRUE 0.13
non-small cell lung cancer KRAS_G12V KIT 106 52 >65yrs 0.28 -0.75 1.13 1183.83 1.00 2032 102 48 4 TRUE 0.25
colorectal cancer KRAS_G12V KIT 213 50 Age:overall -2.14 -4.52 -0.31 400.60 1.00 2022 212 49 1 TRUE 1.20
non-small cell lung cancer KRAS_G12V KIT 169 77 Age:overall 0.23 -0.92 1.24 1249.52 1.00 3318 164 72 5 TRUE 0.16
colorectal cancer KRAS_G12V KDR 13 11 <40yrs -1.39 -3.35 0.07 917.74 1.00 215 13 11 0 TRUE 0.94
colorectal cancer KRAS_G12V KDR 106 29 50-65yrs -1.36 -3.19 0.03 855.31 1.00 942 105 28 1 TRUE 1.06
colorectal cancer KRAS_G12V KDR 62 26 >65yrs -1.33 -3.13 0.11 891.42 1.00 640 61 25 1 TRUE 1.00
non-small cell lung cancer KRAS_G12V KDR 63 58 50-65yrs 0.08 -0.81 0.83 988.50 1.00 1260 60 55 3 TRUE 0.08
non-small cell lung cancer KRAS_G12V KDR 106 88 >65yrs 0.09 -0.72 0.85 991.43 1.00 1996 101 83 5 TRUE 0.09
colorectal cancer KRAS_G12V KDR 181 66 Age:overall -1.36 -3.16 0.10 855.71 1.00 1797 179 64 2 TRUE 1.02
non-small cell lung cancer KRAS_G12V KDR 169 146 Age:overall 0.09 -0.80 0.87 941.40 1.00 3256 161 138 8 TRUE 0.08
colorectal cancer KRAS_G12V RICTOR 42 13 40-50yrs -1.29 -3.06 0.08 616.52 1.01 400 41 12 1 FALSE 1.01
colorectal cancer KRAS_G12V RICTOR 90 24 50-65yrs -1.30 -2.95 0.04 608.54 1.01 856 89 23 1 FALSE 1.07
colorectal cancer KRAS_G12V RICTOR 59 25 >65yrs -1.35 -3.00 -0.04 644.85 1.01 569 59 25 0 FALSE 1.10
non-small cell lung cancer KRAS_G12V RICTOR 62 24 50-65yrs -1.48 -3.94 0.45 275.10 1.01 1230 61 23 1 FALSE 0.67
non-small cell lung cancer KRAS_G12V RICTOR 100 37 >65yrs -1.71 -4.43 0.20 345.74 1.01 1993 100 37 0 FALSE 0.72
uterine cancer KRAS_G12V RICTOR 34 22 50-65yrs -1.69 -5.48 0.42 1061.74 1.00 461 34 22 0 FALSE 0.59
uterine cancer KRAS_G12V RICTOR 17 20 >65yrs -1.18 -4.02 0.98 678.70 1.01 441 16 19 1 FALSE 0.47
colorectal cancer KRAS_G12V RICTOR 191 62 Age:overall -1.32 -3.00 0.04 602.54 1.01 1825 189 60 2 FALSE 1.07
non-small cell lung cancer KRAS_G12V RICTOR 162 61 Age:overall -1.60 -4.30 0.27 330.41 1.01 3223 161 60 1 FALSE 0.71
uterine cancer KRAS_G12V RICTOR 51 42 Age:overall -1.41 -4.45 0.80 1104.30 1.00 902 50 41 1 FALSE 0.57
colorectal cancer KRAS_G12V RAD50 42 13 40-50yrs -2.12 -4.82 -0.38 1097.33 1.00 397 42 13 0 FALSE 1.19
colorectal cancer KRAS_G12V RAD50 90 22 50-65yrs -2.13 -4.88 -0.44 1118.44 1.00 857 90 22 0 FALSE 1.23
colorectal cancer KRAS_G12V RAD50 59 20 >65yrs -2.07 -4.70 -0.34 1143.29 1.00 574 58 19 1 FALSE 1.20
colorectal cancer KRAS_G12V RAD50 191 55 Age:overall -2.10 -4.76 -0.39 1114.96 1.00 1828 190 54 1 FALSE 1.24
colorectal cancer KRAS_G12V CSF1R 45 15 40-50yrs -1.14 -3.00 0.17 692.20 1.00 429 44 14 1 TRUE 0.80
colorectal cancer KRAS_G12V CSF1R 106 21 50-65yrs -1.20 -3.17 0.08 697.16 1.00 950 106 21 0 TRUE 0.86
colorectal cancer KRAS_G12V CSF1R 62 15 >65yrs -1.14 -3.06 0.14 593.30 1.00 646 61 14 1 TRUE 0.81
non-small cell lung cancer KRAS_G12V CSF1R 63 22 50-65yrs 0.67 -0.38 1.64 263.13 1.01 1293 60 19 3 TRUE 0.68
non-small cell lung cancer KRAS_G12V CSF1R 106 45 >65yrs 0.53 -0.46 1.38 333.26 1.01 2036 103 42 3 TRUE 0.55
colorectal cancer KRAS_G12V CSF1R 213 51 Age:overall -1.16 -3.03 0.11 607.05 1.00 2025 211 49 2 TRUE 0.84
non-small cell lung cancer KRAS_G12V CSF1R 169 67 Age:overall 0.61 -0.51 1.56 341.73 1.01 3329 163 61 6 TRUE 0.55
non-small cell lung cancer KRAS_G12V PARK2 62 27 50-65yrs -0.23 -1.75 0.95 1436.89 1.00 1227 61 26 1 FALSE 0.13
non-small cell lung cancer KRAS_G12V PARK2 100 36 >65yrs -0.15 -1.60 1.01 1454.84 1.00 1994 98 34 2 FALSE 0.09
non-small cell lung cancer KRAS_G12V PARK2 162 63 Age:overall -0.17 -1.64 1.02 1472.30 1.00 3221 159 60 3 FALSE 0.09
non-small cell lung cancer KRAS_G12V NTRK2 62 24 50-65yrs 0.17 -1.48 1.63 905.48 1.00 1233 59 21 3 FALSE 0.08
non-small cell lung cancer KRAS_G12V NTRK2 100 39 >65yrs -0.72 -4.34 0.81 839.26 1.00 1993 100 39 0 FALSE 0.22
non-small cell lung cancer KRAS_G12V NTRK2 162 63 Age:overall -0.25 -2.48 1.24 1050.53 1.00 3226 159 60 3 FALSE 0.10
colorectal cancer KRAS_G12V PTCH1 13 16 <40yrs -1.15 -2.40 -0.20 962.58 1.00 193 13 16 0 TRUE 1.38
colorectal cancer KRAS_G12V PTCH1 42 21 40-50yrs -1.04 -2.17 -0.12 1089.50 1.00 392 40 19 2 TRUE 1.34
colorectal cancer KRAS_G12V PTCH1 90 53 50-65yrs -1.12 -2.21 -0.29 885.22 1.00 843 88 51 2 TRUE 1.61
colorectal cancer KRAS_G12V PTCH1 59 55 >65yrs -1.16 -2.33 -0.29 882.89 1.00 545 58 54 1 TRUE 1.61
non-small cell lung cancer KRAS_G12V PTCH1 62 21 50-65yrs -0.52 -2.41 0.84 399.16 1.02 1233 61 20 1 TRUE 0.27
non-small cell lung cancer KRAS_G12V PTCH1 100 35 >65yrs -0.55 -2.50 0.75 306.57 1.02 1994 99 34 1 TRUE 0.29
uterine cancer KRAS_G12V PTCH1 34 32 50-65yrs -5.13 -11.73 -0.97 378.61 1.00 451 34 32 0 TRUE 1.08
uterine cancer KRAS_G12V PTCH1 17 31 >65yrs -5.11 -11.94 -0.70 411.09 1.00 435 17 31 0 TRUE 1.00
colorectal cancer KRAS_G12V PTCH1 204 145 Age:overall -1.12 -2.21 -0.26 938.42 1.00 1973 199 140 5 TRUE 1.58
non-small cell lung cancer KRAS_G12V PTCH1 162 56 Age:overall -0.53 -2.49 0.86 409.07 1.02 3227 160 54 2 TRUE 0.26
uterine cancer KRAS_G12V PTCH1 51 63 Age:overall -5.01 -11.43 -0.72 383.80 1.00 886 51 63 0 TRUE 1.07
colorectal cancer KRAS_G12V TET1 12 16 <40yrs -2.81 -5.62 -0.70 836.43 1.00 189 12 16 0 FALSE 1.64
colorectal cancer KRAS_G12V TET1 41 23 40-50yrs -2.69 -5.29 -0.82 631.03 1.00 382 40 22 1 FALSE 1.61
colorectal cancer KRAS_G12V TET1 86 27 50-65yrs -2.85 -5.54 -0.87 762.56 1.00 830 86 27 0 FALSE 1.72
colorectal cancer KRAS_G12V TET1 55 37 >65yrs -2.86 -5.44 -0.93 747.73 1.00 547 55 37 0 FALSE 1.75
non-small cell lung cancer KRAS_G12V TET1 62 35 50-65yrs 0.13 -0.92 1.21 1191.52 1.00 1219 59 32 3 FALSE 0.09
non-small cell lung cancer KRAS_G12V TET1 100 82 >65yrs -0.08 -1.11 0.76 1117.41 1.00 1950 97 79 3 FALSE 0.06
uterine cancer KRAS_G12V TET1 7 11 40-50yrs -5.07 -10.93 -1.40 427.18 1.01 66 7 11 0 FALSE 1.59
uterine cancer KRAS_G12V TET1 32 33 50-65yrs -5.05 -10.99 -1.43 419.80 1.01 439 32 33 0 FALSE 1.58
uterine cancer KRAS_G12V TET1 17 29 >65yrs -5.05 -10.84 -1.41 388.90 1.01 410 17 29 0 FALSE 1.58
colorectal cancer KRAS_G12V TET1 194 103 Age:overall -2.80 -5.43 -0.92 716.00 1.00 1948 193 102 1 FALSE 1.75
non-small cell lung cancer KRAS_G12V TET1 162 117 Age:overall 0.02 -1.10 1.05 1284.13 1.00 3169 156 111 6 FALSE 0.01
uterine cancer KRAS_G12V TET1 56 73 Age:overall -5.03 -10.89 -1.38 400.79 1.01 915 56 73 0 FALSE 1.60
colorectal cancer KRAS_G12V FGFR2 45 14 40-50yrs -1.89 -4.89 0.02 206.15 1.02 428 44 13 1 TRUE 0.89
colorectal cancer KRAS_G12V FGFR2 106 15 50-65yrs -2.00 -4.91 -0.05 205.17 1.02 953 106 15 0 TRUE 0.95
colorectal cancer KRAS_G12V FGFR2 62 17 >65yrs -2.01 -4.90 -0.01 212.75 1.01 643 62 17 0 TRUE 0.97
uterine cancer KRAS_G12V FGFR2 39 43 50-65yrs -2.50 -5.94 -0.46 1362.60 1.00 500 39 43 0 TRUE 1.10
uterine cancer KRAS_G12V FGFR2 19 56 >65yrs -1.99 -4.84 0.04 1376.87 1.00 451 18 55 1 TRUE 0.98
colorectal cancer KRAS_G12V FGFR2 213 46 Age:overall -1.97 -4.87 -0.06 195.87 1.02 2024 212 45 1 TRUE 0.96
uterine cancer KRAS_G12V FGFR2 58 99 Age:overall -2.21 -5.31 -0.17 1303.33 1.00 951 57 98 1 TRUE 1.01
colorectal cancer KRAS_G12V TBX3 42 13 40-50yrs -0.43 -1.50 0.48 744.54 1.00 399 41 12 1 FALSE 0.39
colorectal cancer KRAS_G12V TBX3 90 30 50-65yrs -0.43 -1.47 0.43 842.32 1.00 852 88 28 2 FALSE 0.41
colorectal cancer KRAS_G12V TBX3 59 30 >65yrs -0.43 -1.46 0.45 875.71 1.00 568 57 28 2 FALSE 0.39
non-small cell lung cancer KRAS_G12V TBX3 62 58 50-65yrs -0.15 -1.25 0.70 1030.94 1.00 1204 60 56 2 FALSE 0.12
non-small cell lung cancer KRAS_G12V TBX3 100 74 >65yrs -0.10 -1.13 0.68 1028.46 1.00 1960 96 70 4 FALSE 0.08
uterine cancer KRAS_G12V TBX3 34 27 50-65yrs -4.94 -12.21 -0.77 815.48 1.00 453 34 27 0 FALSE 1.01
uterine cancer KRAS_G12V TBX3 17 18 >65yrs -4.83 -11.86 -0.39 797.81 1.00 442 17 18 0 FALSE 1.00
colorectal cancer KRAS_G12V TBX3 191 73 Age:overall -0.43 -1.52 0.42 784.67 1.00 1819 186 68 5 FALSE 0.40
non-small cell lung cancer KRAS_G12V TBX3 162 132 Age:overall -0.12 -1.30 0.85 1050.66 1.00 3164 156 126 6 FALSE 0.09
uterine cancer KRAS_G12V TBX3 51 45 Age:overall -4.78 -11.44 -0.56 781.35 1.00 895 51 45 0 FALSE 1.04
colorectal cancer KRAS_G12V HNF1A 106 25 50-65yrs -0.90 -2.77 0.43 847.94 1.00 947 104 23 2 TRUE 0.59
colorectal cancer KRAS_G12V HNF1A 62 19 >65yrs -1.24 -3.88 0.22 688.08 1.00 640 62 19 0 TRUE 0.53
colorectal cancer KRAS_G12V HNF1A 168 44 Age:overall -1.06 -3.21 0.37 705.49 1.00 1587 166 42 2 TRUE 0.59
colorectal cancer KRAS_G12V DICER1 13 11 <40yrs -2.47 -5.21 -0.59 979.94 1.00 197 13 11 0 TRUE 1.45
colorectal cancer KRAS_G12V DICER1 42 19 40-50yrs -2.46 -5.07 -0.62 958.90 1.00 393 42 19 0 TRUE 1.47
colorectal cancer KRAS_G12V DICER1 90 23 50-65yrs -2.42 -5.04 -0.68 933.92 1.00 859 89 22 1 TRUE 1.43
colorectal cancer KRAS_G12V DICER1 59 23 >65yrs -2.48 -5.25 -0.63 954.16 1.00 570 59 23 0 TRUE 1.47
non-small cell lung cancer KRAS_G12V DICER1 62 26 50-65yrs -0.95 -2.82 0.58 917.14 1.00 1228 61 25 1 TRUE 0.57
non-small cell lung cancer KRAS_G12V DICER1 100 59 >65yrs -1.04 -2.93 0.32 1082.69 1.00 1975 99 58 1 TRUE 0.71
uterine cancer KRAS_G12V DICER1 34 36 50-65yrs -1.81 -6.86 0.82 284.85 1.01 454 34 36 0 TRUE 0.40
uterine cancer KRAS_G12V DICER1 19 33 >65yrs 1.27 -0.01 2.47 988.57 1.00 437 14 28 5 TRUE 1.30
colorectal cancer KRAS_G12V DICER1 204 76 Age:overall -2.46 -5.08 -0.64 924.27 1.00 2019 203 75 1 TRUE 1.50
non-small cell lung cancer KRAS_G12V DICER1 162 85 Age:overall -1.00 -2.97 0.44 1009.52 1.00 3203 160 83 2 TRUE 0.59
uterine cancer KRAS_G12V DICER1 53 69 Age:overall -0.14 -3.59 2.49 1351.41 1.00 891 48 64 5 TRUE 0.03
colorectal cancer KRAS_G12V SMAD3 42 33 40-50yrs 0.18 -0.59 0.90 383.88 1.00 385 40 31 2 TRUE 0.22
colorectal cancer KRAS_G12V SMAD3 91 44 50-65yrs 0.22 -0.43 0.95 244.30 1.01 843 86 39 5 TRUE 0.31
colorectal cancer KRAS_G12V SMAD3 59 23 >65yrs 0.34 -0.27 1.18 40.16 1.05 573 54 18 5 TRUE 0.44
colorectal cancer KRAS_G12V SMAD3 192 100 Age:overall 0.24 -0.40 1.00 125.17 1.03 1801 180 88 12 TRUE 0.33
colorectal cancer KRAS_G12V NTRK3 13 11 <40yrs -0.92 -2.20 0.26 743.48 1.00 195 12 10 1 FALSE 0.78
colorectal cancer KRAS_G12V NTRK3 42 16 40-50yrs -0.87 -2.14 0.37 722.49 1.00 399 40 14 2 FALSE 0.72
colorectal cancer KRAS_G12V NTRK3 90 21 50-65yrs -1.03 -2.39 0.10 764.42 1.00 857 90 21 0 FALSE 0.94
colorectal cancer KRAS_G12V NTRK3 59 22 >65yrs -1.03 -2.36 0.16 820.50 1.00 570 59 22 0 FALSE 0.96
non-small cell lung cancer KRAS_G12V NTRK3 62 64 50-65yrs -0.62 -1.88 0.43 1277.04 1.00 1198 59 61 3 FALSE 0.55
non-small cell lung cancer KRAS_G12V NTRK3 100 134 >65yrs -0.87 -2.09 0.06 1155.04 1.00 1914 98 132 2 FALSE 0.93
colorectal cancer KRAS_G12V NTRK3 204 70 Age:overall -0.97 -2.19 0.13 740.40 1.00 2021 201 67 3 FALSE 0.92
non-small cell lung cancer KRAS_G12V NTRK3 162 198 Age:overall -0.73 -2.02 0.35 1250.70 1.00 3112 157 193 5 FALSE 0.62
colorectal cancer KRAS_G12V AXIN1 90 22 50-65yrs -2.61 -6.33 -0.42 1155.23 1.01 858 90 22 0 FALSE 1.05
colorectal cancer KRAS_G12V AXIN1 59 37 >65yrs -2.14 -5.00 -0.32 1081.06 1.00 559 58 36 1 FALSE 1.14
colorectal cancer KRAS_G12V AXIN1 149 59 Age:overall -2.33 -5.71 -0.06 1113.83 1.00 1417 148 58 1 FALSE 1.03
colorectal cancer KRAS_G12V GRIN2A 13 15 <40yrs -0.93 -1.84 -0.08 359.87 1.02 191 13 15 0 FALSE 1.44
colorectal cancer KRAS_G12V GRIN2A 42 29 40-50yrs -0.94 -1.86 -0.08 540.70 1.01 386 42 29 0 FALSE 1.49
colorectal cancer KRAS_G12V GRIN2A 90 50 50-65yrs -0.86 -1.72 -0.02 221.66 1.03 833 85 45 5 FALSE 1.35
colorectal cancer KRAS_G12V GRIN2A 59 42 >65yrs -0.93 -1.83 -0.09 412.88 1.02 554 58 41 1 FALSE 1.50
non-small cell lung cancer KRAS_G12V GRIN2A 6 11 40-50yrs 0.32 -0.34 1.02 446.97 1.00 176 5 10 1 FALSE 0.44
non-small cell lung cancer KRAS_G12V GRIN2A 62 70 50-65yrs 0.27 -0.39 0.92 696.33 1.00 1191 59 67 3 FALSE 0.38
non-small cell lung cancer KRAS_G12V GRIN2A 100 110 >65yrs 0.32 -0.26 0.92 307.10 1.00 1932 92 102 8 FALSE 0.51
uterine cancer KRAS_G12V GRIN2A 7 12 40-50yrs -0.40 -2.03 1.05 842.85 1.00 79 6 11 1 FALSE 0.21
uterine cancer KRAS_G12V GRIN2A 34 35 50-65yrs -0.60 -2.14 0.66 963.82 1.00 451 33 34 1 FALSE 0.39
uterine cancer KRAS_G12V GRIN2A 17 26 >65yrs -0.47 -2.09 0.83 872.84 1.00 439 16 25 1 FALSE 0.27
colorectal cancer KRAS_G12V GRIN2A 204 136 Age:overall -0.91 -1.76 -0.11 299.88 1.02 1964 198 130 6 FALSE 1.52
non-small cell lung cancer KRAS_G12V GRIN2A 168 191 Age:overall 0.31 -0.30 0.93 406.77 1.00 3299 156 179 12 FALSE 0.47
uterine cancer KRAS_G12V GRIN2A 58 73 Age:overall -0.50 -2.08 0.82 806.76 1.00 969 55 70 3 FALSE 0.30
colorectal cancer KRAS_G12V PALB2 13 13 <40yrs -5.27 -11.92 -1.14 1202.83 1.00 193 13 13 0 TRUE 1.19
colorectal cancer KRAS_G12V PALB2 90 18 50-65yrs -5.28 -11.73 -1.15 1261.36 1.00 860 90 18 0 TRUE 1.21
colorectal cancer KRAS_G12V PALB2 59 20 >65yrs -5.31 -11.99 -1.26 1228.97 1.00 572 59 20 0 TRUE 1.22
non-small cell lung cancer KRAS_G12V PALB2 62 30 50-65yrs 0.71 -0.52 1.78 366.46 1.01 1230 58 26 4 TRUE 0.63
non-small cell lung cancer KRAS_G12V PALB2 100 29 >65yrs -0.55 -4.61 1.10 97.34 1.05 1999 100 29 0 TRUE 0.14
colorectal cancer KRAS_G12V PALB2 162 51 Age:overall -5.25 -11.76 -1.21 1233.95 1.00 1625 162 51 0 TRUE 1.22
non-small cell lung cancer KRAS_G12V PALB2 162 59 Age:overall 0.12 -2.94 1.66 209.09 1.03 3229 158 55 4 TRUE 0.04
colorectal cancer KRAS_G12V CTCF 42 20 40-50yrs -1.11 -2.58 0.02 886.74 1.00 393 41 19 1 FALSE 1.05
colorectal cancer KRAS_G12V CTCF 90 30 50-65yrs -1.14 -2.59 0.01 827.19 1.00 851 89 29 1 FALSE 1.09
colorectal cancer KRAS_G12V CTCF 59 32 >65yrs -1.13 -2.54 0.02 896.21 1.00 564 58 31 1 FALSE 1.08
uterine cancer KRAS_G12V CTCF 7 16 40-50yrs -0.02 -1.06 1.11 1010.23 1.00 70 5 14 2 FALSE 0.01
uterine cancer KRAS_G12V CTCF 34 85 50-65yrs -0.42 -1.54 0.43 569.38 1.00 408 32 83 2 FALSE 0.39
uterine cancer KRAS_G12V CTCF 17 65 >65yrs 0.01 -0.97 1.03 1118.72 1.00 402 13 61 4 FALSE 0.01
colorectal cancer KRAS_G12V CTCF 191 82 Age:overall -1.13 -2.55 -0.03 866.62 1.00 1808 188 79 3 FALSE 1.10
uterine cancer KRAS_G12V CTCF 58 166 Age:overall -0.15 -1.05 0.78 1067.18 1.00 880 50 158 8 FALSE 0.12
colorectal cancer KRAS_G12V CDH1 106 22 50-65yrs -0.23 -1.81 0.90 1389.20 1.00 950 105 21 1 TRUE 0.13
colorectal cancer KRAS_G12V CDH1 63 18 >65yrs 0.10 -1.24 1.34 1176.17 1.00 647 60 15 3 TRUE 0.06
colorectal cancer KRAS_G12V CDH1 169 40 Age:overall -0.07 -1.55 1.20 1552.38 1.00 1597 165 36 4 TRUE 0.04
colorectal cancer KRAS_G12V CDK12 42 13 40-50yrs -1.05 -2.58 0.13 899.91 1.00 398 40 11 2 FALSE 0.94
colorectal cancer KRAS_G12V CDK12 90 39 50-65yrs -1.13 -2.62 -0.02 832.61 1.00 844 89 38 1 FALSE 1.09
colorectal cancer KRAS_G12V CDK12 59 28 >65yrs -1.17 -2.71 -0.10 935.46 1.00 569 59 28 0 FALSE 1.11
non-small cell lung cancer KRAS_G12V CDK12 62 15 50-65yrs -4.49 -11.71 -0.60 69.93 1.04 1238 62 15 0 FALSE 0.88
non-small cell lung cancer KRAS_G12V CDK12 100 42 >65yrs -4.54 -11.74 -0.71 66.44 1.04 1988 100 42 0 FALSE 0.90
colorectal cancer KRAS_G12V CDK12 191 80 Age:overall -1.12 -2.60 -0.03 831.16 1.00 1811 188 77 3 FALSE 1.09
non-small cell lung cancer KRAS_G12V CDK12 162 57 Age:overall -4.49 -11.71 -0.68 67.49 1.04 3226 162 57 0 FALSE 0.90
non-small cell lung cancer KRAS_G12V STK11 6 19 40-50yrs 0.87 -0.21 2.14 1676.86 1.00 178 4 17 2 TRUE 0.87
non-small cell lung cancer KRAS_G12V STK11 65 196 50-65yrs 1.17 0.58 1.70 1188.65 1.00 1143 41 172 24 TRUE 4.16
non-small cell lung cancer KRAS_G12V STK11 106 326 >65yrs 0.08 -0.49 0.61 1286.90 1.00 1777 92 312 14 TRUE 0.10
non-small cell lung cancer KRAS_G12V STK11 177 541 Age:overall 0.71 -0.10 1.61 1489.55 1.00 3098 137 501 40 TRUE 0.97
colorectal cancer KRAS_G12V DNMT1 12 13 <40yrs -1.66 -3.27 -0.12 166.93 1.01 186 12 13 0 FALSE 1.45
colorectal cancer KRAS_G12V DNMT1 41 18 40-50yrs -1.63 -3.27 -0.16 171.03 1.01 382 40 17 1 FALSE 1.45
colorectal cancer KRAS_G12V DNMT1 86 36 50-65yrs -1.66 -3.29 -0.14 161.99 1.01 823 85 35 1 FALSE 1.48
colorectal cancer KRAS_G12V DNMT1 55 23 >65yrs -1.67 -3.30 -0.14 159.53 1.01 556 55 23 0 FALSE 1.48
colorectal cancer KRAS_G12V DNMT1 194 90 Age:overall -1.65 -3.30 -0.16 157.41 1.01 1947 192 88 2 FALSE 1.50
colorectal cancer KRAS_G12V BRD4 90 40 50-65yrs -1.04 -2.48 0.03 1161.72 1.00 844 88 38 2 FALSE 1.07
colorectal cancer KRAS_G12V BRD4 59 33 >65yrs -1.08 -2.57 -0.01 1319.29 1.01 560 58 32 1 FALSE 1.07
non-small cell lung cancer KRAS_G12V BRD4 62 15 50-65yrs -1.24 -4.19 0.83 841.38 1.00 1239 61 14 1 FALSE 0.47
non-small cell lung cancer KRAS_G12V BRD4 100 37 >65yrs -1.67 -5.22 0.34 924.30 1.00 1993 100 37 0 FALSE 0.59
uterine cancer KRAS_G12V BRD4 34 32 50-65yrs -5.22 -12.06 -1.00 263.09 1.02 454 34 32 0 FALSE 1.14
uterine cancer KRAS_G12V BRD4 17 31 >65yrs -5.14 -12.28 -0.77 257.26 1.02 429 17 31 0 FALSE 1.11
colorectal cancer KRAS_G12V BRD4 149 73 Age:overall -1.07 -2.61 0.01 1185.29 1.00 1404 146 70 3 FALSE 0.99
non-small cell lung cancer KRAS_G12V BRD4 162 52 Age:overall -1.44 -4.49 0.64 890.26 1.01 3232 161 51 1 FALSE 0.54
uterine cancer KRAS_G12V BRD4 51 63 Age:overall -5.11 -12.00 -0.92 259.33 1.02 883 51 63 0 FALSE 1.12
colorectal cancer KRAS_G12V ASXL1 42 21 40-50yrs -0.76 -1.95 0.08 507.15 1.01 390 41 20 1 TRUE 0.91
colorectal cancer KRAS_G12V ASXL1 90 40 50-65yrs -0.74 -1.85 0.08 478.89 1.01 842 87 37 3 TRUE 0.91
colorectal cancer KRAS_G12V ASXL1 59 40 >65yrs -0.79 -1.86 -0.01 389.54 1.01 557 58 39 1 TRUE 1.01
non-small cell lung cancer KRAS_G12V ASXL1 62 29 50-65yrs 0.39 -0.76 1.26 77.09 1.04 1226 60 27 2 TRUE 0.32
non-small cell lung cancer KRAS_G12V ASXL1 100 53 >65yrs 0.41 -0.68 1.23 57.69 1.05 1993 96 49 4 TRUE 0.37
uterine cancer KRAS_G12V ASXL1 34 19 50-65yrs -1.85 -5.56 0.44 1092.06 1.00 463 34 19 0 TRUE 0.61
uterine cancer KRAS_G12V ASXL1 17 29 >65yrs -1.21 -3.90 0.86 884.00 1.00 434 16 28 1 TRUE 0.47
colorectal cancer KRAS_G12V ASXL1 191 101 Age:overall -0.76 -1.84 0.03 431.57 1.01 1789 186 96 5 TRUE 1.00
non-small cell lung cancer KRAS_G12V ASXL1 162 82 Age:overall 0.40 -0.75 1.30 72.88 1.04 3219 156 76 6 TRUE 0.32
uterine cancer KRAS_G12V ASXL1 51 48 Age:overall -1.50 -4.51 0.76 894.85 1.00 897 50 47 1 TRUE 0.54
colorectal cancer KRAS_G12V EP300 13 15 <40yrs -1.07 -2.46 0.08 1394.62 1.00 192 13 15 0 TRUE 1.01
colorectal cancer KRAS_G12V EP300 42 16 40-50yrs -0.98 -2.20 0.11 1265.31 1.00 395 41 15 1 TRUE 1.01
colorectal cancer KRAS_G12V EP300 90 38 50-65yrs -0.96 -2.11 0.01 1279.36 1.00 849 88 36 2 TRUE 1.11
colorectal cancer KRAS_G12V EP300 59 56 >65yrs -1.01 -2.17 -0.01 1400.14 1.00 548 57 54 2 TRUE 1.21
non-small cell lung cancer KRAS_G12V EP300 62 30 50-65yrs -0.66 -2.18 0.59 1283.51 1.00 1226 61 29 1 TRUE 0.45
non-small cell lung cancer KRAS_G12V EP300 101 74 >65yrs -0.67 -2.03 0.42 1358.97 1.00 1964 99 72 2 TRUE 0.53
uterine cancer KRAS_G12V EP300 7 15 40-50yrs -1.07 -4.80 0.82 1347.56 1.00 76 7 15 0 TRUE 0.34
uterine cancer KRAS_G12V EP300 34 37 50-65yrs -1.35 -4.60 0.46 1019.14 1.00 448 34 37 0 TRUE 0.51
uterine cancer KRAS_G12V EP300 18 47 >65yrs 0.61 -0.72 1.91 1314.56 1.00 424 13 42 5 TRUE 0.43
colorectal cancer KRAS_G12V EP300 204 125 Age:overall -1.00 -2.15 -0.07 1312.44 1.00 1984 199 120 5 TRUE 1.25
non-small cell lung cancer KRAS_G12V EP300 163 104 Age:overall -0.64 -2.18 0.66 1324.82 1.00 3190 160 101 3 TRUE 0.43
uterine cancer KRAS_G12V EP300 59 99 Age:overall -0.58 -2.94 0.94 1383.08 1.00 948 54 94 5 TRUE 0.26
colorectal cancer KRAS_G12V ERBB4 13 17 <40yrs -0.67 -1.72 0.25 1164.09 1.00 211 13 17 0 TRUE 0.74
colorectal cancer KRAS_G12V ERBB4 45 20 40-50yrs -0.69 -1.79 0.19 1219.97 1.00 423 45 20 0 TRUE 0.79
colorectal cancer KRAS_G12V ERBB4 107 60 50-65yrs -0.47 -1.29 0.32 1287.27 1.00 922 100 53 7 TRUE 0.59
colorectal cancer KRAS_G12V ERBB4 62 41 >65yrs -0.68 -1.65 0.13 1192.89 1.00 622 61 40 1 TRUE 0.86
non-small cell lung cancer KRAS_G12V ERBB4 64 80 50-65yrs -0.20 -1.15 0.67 1017.58 1.00 1248 59 75 5 TRUE 0.18
non-small cell lung cancer KRAS_G12V ERBB4 106 105 >65yrs -0.48 -1.64 0.35 1202.00 1.00 1988 104 103 2 TRUE 0.47
colorectal cancer KRAS_G12V ERBB4 227 138 Age:overall -0.63 -1.51 0.17 1341.19 1.00 2178 219 130 8 TRUE 0.83
non-small cell lung cancer KRAS_G12V ERBB4 170 185 Age:overall -0.33 -1.41 0.63 1456.17 1.00 3236 163 178 7 TRUE 0.29
colorectal cancer KRAS_G12V MDC1 86 30 50-65yrs -2.17 -4.89 -0.27 564.66 1.00 828 86 30 0 FALSE 1.14
colorectal cancer KRAS_G12V MDC1 55 19 >65yrs -1.97 -4.55 -0.04 478.56 1.00 560 54 18 1 FALSE 1.06
non-small cell lung cancer KRAS_G12V MDC1 63 36 50-65yrs -0.17 -1.39 0.80 1139.35 1.00 1213 61 34 2 FALSE 0.12
non-small cell lung cancer KRAS_G12V MDC1 100 53 >65yrs -0.21 -1.38 0.73 1046.04 1.00 1979 98 51 2 FALSE 0.15
colorectal cancer KRAS_G12V MDC1 141 49 Age:overall -2.06 -4.73 -0.16 611.41 1.00 1388 140 48 1 FALSE 1.11
non-small cell lung cancer KRAS_G12V MDC1 163 89 Age:overall -0.20 -1.57 0.84 1165.51 1.00 3192 159 85 4 FALSE 0.13
colorectal cancer KRAS_G12V RECQL4 12 13 <40yrs -2.48 -5.29 -0.67 988.77 1.00 189 12 13 0 TRUE 1.48
colorectal cancer KRAS_G12V RECQL4 41 13 40-50yrs -2.44 -5.22 -0.61 862.18 1.00 384 40 12 1 TRUE 1.45
colorectal cancer KRAS_G12V RECQL4 86 34 50-65yrs -2.50 -5.34 -0.68 982.46 1.00 824 86 34 0 TRUE 1.51
colorectal cancer KRAS_G12V RECQL4 55 21 >65yrs -2.50 -5.23 -0.68 994.77 1.00 558 55 21 0 TRUE 1.52
non-small cell lung cancer KRAS_G12V RECQL4 62 25 50-65yrs -0.62 -2.40 0.80 1230.86 1.00 1223 61 24 1 TRUE 0.35
non-small cell lung cancer KRAS_G12V RECQL4 100 35 >65yrs -0.64 -2.45 0.76 1355.24 1.00 1990 99 34 1 TRUE 0.38
colorectal cancer KRAS_G12V RECQL4 194 81 Age:overall -2.48 -5.25 -0.70 919.17 1.00 1955 193 80 1 TRUE 1.51
non-small cell lung cancer KRAS_G12V RECQL4 162 60 Age:overall -0.64 -2.49 0.80 1339.02 1.00 3213 160 58 2 TRUE 0.34
colorectal cancer KRAS_G12V MED12 13 13 <40yrs -0.38 -1.39 0.57 1215.20 1.00 194 12 12 1 TRUE 0.35
colorectal cancer KRAS_G12V MED12 42 18 40-50yrs -0.29 -1.22 0.68 1182.15 1.00 394 39 15 3 TRUE 0.27
colorectal cancer KRAS_G12V MED12 90 35 50-65yrs -0.55 -1.62 0.27 804.47 1.00 850 90 35 0 TRUE 0.62
colorectal cancer KRAS_G12V MED12 59 42 >65yrs -0.38 -1.25 0.40 1055.16 1.00 556 56 39 3 TRUE 0.43
non-small cell lung cancer KRAS_G12V MED12 62 64 50-65yrs -0.54 -1.58 0.41 421.17 1.01 1199 59 61 3 TRUE 0.54
non-small cell lung cancer KRAS_G12V MED12 100 104 >65yrs -0.64 -1.75 0.18 430.23 1.01 1932 98 102 2 TRUE 0.69
uterine cancer KRAS_G12V MED12 34 73 50-65yrs -1.08 -2.56 0.12 1425.94 1.00 423 32 71 2 TRUE 0.92
uterine cancer KRAS_G12V MED12 17 48 >65yrs -1.02 -2.78 0.41 1385.35 1.00 420 16 47 1 TRUE 0.67
colorectal cancer KRAS_G12V MED12 204 108 Age:overall -0.40 -1.27 0.40 1038.33 1.00 1994 197 101 7 TRUE 0.47
non-small cell lung cancer KRAS_G12V MED12 162 168 Age:overall -0.58 -1.72 0.35 460.74 1.00 3131 157 163 5 TRUE 0.57
uterine cancer KRAS_G12V MED12 51 121 Age:overall -1.01 -2.76 0.59 1473.39 1.00 843 48 118 3 TRUE 0.60
colorectal cancer KRAS_G12V ERCC5 41 13 40-50yrs -0.87 -2.78 0.91 12.58 1.24 385 40 12 1 TRUE 0.41
colorectal cancer KRAS_G12V ERCC5 86 20 50-65yrs -0.93 -2.87 0.90 11.59 1.26 834 86 20 0 TRUE 0.43
colorectal cancer KRAS_G12V ERCC5 55 22 >65yrs -0.89 -2.77 0.90 12.28 1.25 559 54 21 1 TRUE 0.42
non-small cell lung cancer KRAS_G12V ERCC5 62 28 50-65yrs -4.97 -11.45 -0.98 445.14 1.00 1220 62 28 0 TRUE 1.08
non-small cell lung cancer KRAS_G12V ERCC5 100 43 >65yrs -4.98 -11.46 -1.02 441.00 1.01 1983 100 43 0 TRUE 1.08
uterine cancer KRAS_G12V ERCC5 7 15 40-50yrs -2.16 -5.96 0.22 1258.41 1.00 65 7 15 0 TRUE 0.78
uterine cancer KRAS_G12V ERCC5 32 17 50-65yrs -1.40 -4.37 0.69 1354.64 1.00 445 31 16 1 TRUE 0.55
uterine cancer KRAS_G12V ERCC5 17 17 >65yrs -2.10 -5.75 0.54 1243.91 1.00 420 17 17 0 TRUE 0.70
colorectal cancer KRAS_G12V ERCC5 182 55 Age:overall -0.89 -2.80 0.90 12.18 1.25 1778 180 53 2 TRUE 0.42
non-small cell lung cancer KRAS_G12V ERCC5 162 71 Age:overall -4.94 -11.45 -0.93 443.21 1.00 3203 162 71 0 TRUE 1.07
uterine cancer KRAS_G12V ERCC5 56 49 Age:overall -1.86 -5.16 0.40 1449.17 1.00 930 55 48 1 TRUE 0.74
colorectal cancer KRAS_G12V PIK3CD 41 17 40-50yrs -2.42 -5.33 -0.42 1370.29 1.00 380 41 17 0 FALSE 1.16
colorectal cancer KRAS_G12V PIK3CD 86 18 50-65yrs -2.17 -4.95 -0.28 1297.71 1.00 836 85 17 1 FALSE 1.13
colorectal cancer KRAS_G12V PIK3CD 55 31 >65yrs -2.45 -5.47 -0.51 1278.92 1.00 551 55 31 0 FALSE 1.28
colorectal cancer KRAS_G12V PIK3CD 182 66 Age:overall -2.35 -5.14 -0.44 1378.09 1.00 1767 181 65 1 FALSE 1.28
colorectal cancer KRAS_G12V BRCA1 13 19 <40yrs -1.71 -3.78 -0.15 1412.38 1.00 193 13 19 0 TRUE 1.15
colorectal cancer KRAS_G12V BRCA1 42 15 40-50yrs -1.49 -3.56 0.08 1487.73 1.00 396 41 14 1 TRUE 0.99
colorectal cancer KRAS_G12V BRCA1 90 19 50-65yrs -1.52 -3.42 -0.02 1362.62 1.00 860 89 18 1 TRUE 1.09
colorectal cancer KRAS_G12V BRCA1 59 26 >65yrs -1.77 -3.84 -0.22 1509.47 1.00 568 59 26 0 TRUE 1.29
non-small cell lung cancer KRAS_G12V BRCA1 62 32 50-65yrs -0.64 -2.04 0.60 156.29 1.02 1223 61 31 1 TRUE 0.44
non-small cell lung cancer KRAS_G12V BRCA1 100 61 >65yrs -0.64 -1.97 0.54 137.63 1.02 1973 98 59 2 TRUE 0.47
colorectal cancer KRAS_G12V BRCA1 204 79 Age:overall -1.62 -3.47 -0.17 1482.63 1.00 2017 202 77 2 TRUE 1.30
non-small cell lung cancer KRAS_G12V BRCA1 162 93 Age:overall -0.65 -2.07 0.68 171.05 1.02 3196 159 90 3 TRUE 0.43
colorectal cancer KRAS_G12V RBM10 90 38 50-65yrs -1.27 -3.17 0.06 686.49 1.00 843 88 36 2 FALSE 0.93
colorectal cancer KRAS_G12V RBM10 59 22 >65yrs -1.51 -3.96 -0.13 658.86 1.00 572 59 22 0 FALSE 0.91
non-small cell lung cancer KRAS_G12V RBM10 6 11 40-50yrs -0.12 -1.38 0.87 1493.97 1.00 175 6 11 0 FALSE 0.08
non-small cell lung cancer KRAS_G12V RBM10 62 106 50-65yrs -0.12 -0.96 0.54 1398.67 1.00 1160 58 102 4 FALSE 0.12
non-small cell lung cancer KRAS_G12V RBM10 100 265 >65yrs 0.13 -0.43 0.63 1520.32 1.00 1788 85 250 15 FALSE 0.19
uterine cancer KRAS_G12V RBM10 7 13 40-50yrs -0.55 -2.75 1.24 1374.87 1.00 75 6 12 1 FALSE 0.23
uterine cancer KRAS_G12V RBM10 34 20 50-65yrs -1.19 -3.82 0.50 1358.47 1.00 459 34 20 0 FALSE 0.54
uterine cancer KRAS_G12V RBM10 17 19 >65yrs -0.53 -2.57 1.18 1227.66 1.00 445 16 18 1 FALSE 0.23
colorectal cancer KRAS_G12V RBM10 149 60 Age:overall -1.37 -3.52 0.03 735.59 1.00 1415 147 58 2 FALSE 0.90
non-small cell lung cancer KRAS_G12V RBM10 168 382 Age:overall -0.04 -0.92 0.71 1722.43 1.00 3123 149 363 19 FALSE 0.04
uterine cancer KRAS_G12V RBM10 58 52 Age:overall -0.74 -2.77 0.89 1261.82 1.00 979 56 50 2 FALSE 0.37
colorectal cancer KRAS_G12V TSC1 90 23 50-65yrs -1.92 -4.74 0.00 1115.79 1.00 858 89 22 1 TRUE 0.91
colorectal cancer KRAS_G12V TSC1 59 27 >65yrs -2.33 -6.00 -0.32 1085.25 1.00 568 59 27 0 TRUE 0.97
non-small cell lung cancer KRAS_G12V TSC1 62 23 50-65yrs 0.01 -1.34 1.25 1305.49 1.00 1233 60 21 2 TRUE 0.00
non-small cell lung cancer KRAS_G12V TSC1 100 33 >65yrs -0.13 -1.59 1.04 1334.87 1.00 1996 99 32 1 TRUE 0.07
uterine cancer KRAS_G12V TSC1 34 32 50-65yrs -0.78 -2.62 0.79 1333.57 1.00 458 33 31 1 TRUE 0.42
uterine cancer KRAS_G12V TSC1 17 19 >65yrs -0.51 -2.47 1.29 1025.01 1.00 440 16 18 1 TRUE 0.22
colorectal cancer KRAS_G12V TSC1 149 50 Age:overall -2.12 -5.36 -0.07 1143.32 1.00 1426 148 49 1 TRUE 0.92
non-small cell lung cancer KRAS_G12V TSC1 162 56 Age:overall -0.07 -1.51 1.15 1287.85 1.00 3229 159 53 3 TRUE 0.04
uterine cancer KRAS_G12V TSC1 51 51 Age:overall -0.65 -2.77 1.24 1158.60 1.00 898 49 49 2 TRUE 0.28
colorectal cancer KRAS_G12V FLCN 90 23 50-65yrs -2.11 -5.19 -0.06 314.20 1.02 859 90 23 0 TRUE 0.93
colorectal cancer KRAS_G12V FLCN 59 19 >65yrs -1.88 -4.63 0.21 296.97 1.01 572 58 18 1 TRUE 0.87
colorectal cancer KRAS_G12V FLCN 149 42 Age:overall -1.97 -4.87 0.05 320.99 1.02 1431 148 41 1 TRUE 0.91
colorectal cancer KRAS_G12V NF1 13 23 <40yrs -1.75 -3.18 -0.56 966.79 1.01 189 13 23 0 TRUE 2.14
colorectal cancer KRAS_G12V NF1 42 21 40-50yrs -1.77 -3.24 -0.59 929.80 1.01 395 42 21 0 TRUE 2.15
colorectal cancer KRAS_G12V NF1 90 58 50-65yrs -1.75 -3.25 -0.63 774.28 1.01 829 89 57 1 TRUE 2.21
colorectal cancer KRAS_G12V NF1 59 40 >65yrs -1.68 -3.05 -0.53 518.49 1.01 563 57 38 2 TRUE 2.04
non-small cell lung cancer KRAS_G12V NF1 6 12 40-50yrs -0.53 -1.43 0.30 1318.67 1.00 175 6 12 0 TRUE 0.64
non-small cell lung cancer KRAS_G12V NF1 62 110 50-65yrs -0.56 -1.43 0.15 1055.43 1.00 1161 60 108 2 TRUE 0.85
non-small cell lung cancer KRAS_G12V NF1 101 191 >65yrs -0.44 -1.11 0.22 721.46 1.00 1871 93 183 8 TRUE 0.70
uterine cancer KRAS_G12V NF1 7 21 40-50yrs -5.67 -12.08 -1.43 1218.82 1.00 71 7 21 0 TRUE 1.34
uterine cancer KRAS_G12V NF1 34 62 50-65yrs -5.71 -11.97 -1.63 1217.29 1.00 441 34 62 0 TRUE 1.37
uterine cancer KRAS_G12V NF1 17 31 >65yrs -5.69 -12.32 -1.47 1205.69 1.00 432 17 31 0 TRUE 1.33
colorectal cancer KRAS_G12V NF1 204 142 Age:overall -1.74 -3.13 -0.64 909.80 1.01 1976 201 139 3 TRUE 2.25
non-small cell lung cancer KRAS_G12V NF1 169 313 Age:overall -0.51 -1.24 0.19 967.99 1.00 3207 159 303 10 TRUE 0.80
uterine cancer KRAS_G12V NF1 58 114 Age:overall -5.65 -11.90 -1.57 1255.55 1.00 944 58 114 0 TRUE 1.36
colorectal cancer KRAS_G12V FLT1 42 13 40-50yrs -2.60 -4.84 -0.63 189.60 1.01 398 42 13 0 FALSE 1.99
colorectal cancer KRAS_G12V FLT1 90 40 50-65yrs -2.58 -4.83 -0.65 168.09 1.01 845 89 39 1 FALSE 2.02
colorectal cancer KRAS_G12V FLT1 59 25 >65yrs -2.61 -4.86 -0.68 168.67 1.01 570 59 25 0 FALSE 2.02
non-small cell lung cancer KRAS_G12V FLT1 62 51 50-65yrs 0.38 -0.53 1.07 21.98 1.06 1211 58 47 4 FALSE 0.47
non-small cell lung cancer KRAS_G12V FLT1 100 80 >65yrs 0.32 -0.61 0.88 8.64 1.13 1959 96 76 4 FALSE 0.38
uterine cancer KRAS_G12V FLT1 34 35 50-65yrs -5.06 -11.85 -0.78 1048.96 1.00 451 34 35 0 FALSE 1.07
uterine cancer KRAS_G12V FLT1 17 13 >65yrs -5.01 -12.06 -0.28 956.41 1.00 445 17 13 0 FALSE 0.98
colorectal cancer KRAS_G12V FLT1 191 78 Age:overall -2.60 -4.83 -0.70 169.50 1.01 1813 190 77 1 FALSE 2.02
non-small cell lung cancer KRAS_G12V FLT1 162 131 Age:overall 0.36 -0.58 1.01 22.84 1.07 3170 154 123 8 FALSE 0.41
uterine cancer KRAS_G12V FLT1 51 48 Age:overall -4.82 -11.42 -0.29 975.10 1.00 896 51 48 0 FALSE 0.99
colorectal cancer KRAS_G12V RPTOR 42 16 40-50yrs -0.03 -1.06 0.86 1320.23 1.00 397 40 14 2 FALSE 0.02
colorectal cancer KRAS_G12V RPTOR 90 23 50-65yrs -0.02 -1.04 0.81 1317.85 1.00 858 87 20 3 FALSE 0.02
colorectal cancer KRAS_G12V RPTOR 59 24 >65yrs -0.10 -1.14 0.78 1348.17 1.00 570 58 23 1 FALSE 0.08
non-small cell lung cancer KRAS_G12V RPTOR 62 22 50-65yrs 0.57 -0.80 1.52 1257.86 1.00 1232 61 21 1 FALSE 0.48
non-small cell lung cancer KRAS_G12V RPTOR 101 40 >65yrs 0.75 -0.24 1.59 1410.46 1.00 1993 96 35 5 FALSE 1.00
colorectal cancer KRAS_G12V RPTOR 191 63 Age:overall -0.06 -1.05 0.78 1201.50 1.00 1825 185 57 6 FALSE 0.04
non-small cell lung cancer KRAS_G12V RPTOR 163 62 Age:overall 0.65 -0.63 1.63 1270.23 1.00 3225 157 56 6 FALSE 0.57
colorectal cancer KRAS_G12V RASA1 42 21 40-50yrs -0.93 -2.26 0.23 90.54 1.06 394 41 20 1 FALSE 0.86
colorectal cancer KRAS_G12V RASA1 90 24 50-65yrs -0.91 -2.17 0.23 69.92 1.06 861 88 22 2 FALSE 0.84
colorectal cancer KRAS_G12V RASA1 59 20 >65yrs -0.97 -2.32 0.19 96.90 1.05 575 59 20 0 FALSE 0.91
non-small cell lung cancer KRAS_G12V RASA1 62 26 50-65yrs -0.55 -2.10 0.73 1443.72 1.00 1228 61 25 1 FALSE 0.34
non-small cell lung cancer KRAS_G12V RASA1 100 67 >65yrs -0.59 -1.98 0.58 1458.57 1.00 1965 98 65 2 FALSE 0.44
uterine cancer KRAS_G12V RASA1 34 59 50-65yrs -1.36 -3.25 0.05 1327.95 1.00 443 33 58 1 FALSE 0.92
uterine cancer KRAS_G12V RASA1 17 30 >65yrs -0.98 -3.16 0.77 1487.06 1.00 435 16 29 1 FALSE 0.49
colorectal cancer KRAS_G12V RASA1 191 65 Age:overall -0.94 -2.27 0.23 83.37 1.06 1830 188 62 3 FALSE 0.88
non-small cell lung cancer KRAS_G12V RASA1 162 93 Age:overall -0.55 -2.09 0.85 1477.52 1.00 3193 159 90 3 FALSE 0.32
uterine cancer KRAS_G12V RASA1 51 89 Age:overall -1.18 -3.31 0.73 1369.46 1.00 878 49 87 2 FALSE 0.59
colorectal cancer KRAS_G12V EPHA5 13 17 <40yrs -0.99 -2.12 -0.04 1254.62 1.00 190 13 17 0 FALSE 1.17
colorectal cancer KRAS_G12V EPHA5 42 27 40-50yrs -1.02 -2.16 -0.14 1158.11 1.00 390 42 27 0 FALSE 1.29
colorectal cancer KRAS_G12V EPHA5 90 46 50-65yrs -0.90 -1.87 -0.03 966.71 1.00 840 87 43 3 FALSE 1.20
colorectal cancer KRAS_G12V EPHA5 59 54 >65yrs -0.89 -1.89 0.03 1024.06 1.00 547 56 51 3 FALSE 1.16
non-small cell lung cancer KRAS_G12V EPHA5 63 99 50-65yrs 0.16 -0.50 0.79 1164.05 1.00 1172 57 93 6 FALSE 0.20
non-small cell lung cancer KRAS_G12V EPHA5 100 151 >65yrs 0.14 -0.49 0.70 1144.95 1.00 1896 92 143 8 FALSE 0.19
uterine cancer KRAS_G12V EPHA5 7 12 40-50yrs -0.95 -2.91 0.62 1469.01 1.00 75 7 12 0 FALSE 0.53
uterine cancer KRAS_G12V EPHA5 34 50 50-65yrs -0.97 -2.53 0.26 1517.60 1.00 447 33 49 1 FALSE 0.73
uterine cancer KRAS_G12V EPHA5 17 32 >65yrs -0.57 -2.21 0.86 1456.33 1.00 436 15 30 2 FALSE 0.33
colorectal cancer KRAS_G12V EPHA5 204 144 Age:overall -0.95 -1.94 -0.11 978.77 1.00 1967 198 138 6 FALSE 1.33
non-small cell lung cancer KRAS_G12V EPHA5 163 250 Age:overall 0.16 -0.55 0.83 1130.76 1.00 3068 149 236 14 FALSE 0.18
uterine cancer KRAS_G12V EPHA5 58 94 Age:overall -0.82 -2.36 0.52 1515.27 1.00 958 55 91 3 FALSE 0.57
colorectal cancer KRAS_G12V AR 42 22 40-50yrs -0.22 -1.16 0.69 1337.94 1.00 392 39 19 3 TRUE 0.20
colorectal cancer KRAS_G12V AR 90 38 50-65yrs -0.33 -1.23 0.46 1502.98 1.00 843 87 35 3 TRUE 0.35
colorectal cancer KRAS_G12V AR 59 48 >65yrs -0.40 -1.32 0.37 1554.79 1.00 551 57 46 2 TRUE 0.44
non-small cell lung cancer KRAS_G12V AR 62 48 50-65yrs 0.48 -0.47 1.37 1379.74 1.00 1216 57 43 5 TRUE 0.54
non-small cell lung cancer KRAS_G12V AR 100 55 >65yrs 0.14 -1.05 1.02 1471.62 1.00 1978 98 53 2 TRUE 0.10
uterine cancer KRAS_G12V AR 34 27 50-65yrs -1.90 -5.29 0.17 1004.74 1.00 458 34 27 0 TRUE 0.75
uterine cancer KRAS_G12V AR 17 29 >65yrs -1.34 -4.23 0.72 1164.95 1.00 433 16 28 1 TRUE 0.55
colorectal cancer KRAS_G12V AR 191 108 Age:overall -0.31 -1.21 0.47 1483.64 1.00 1786 183 100 8 TRUE 0.33
non-small cell lung cancer KRAS_G12V AR 162 103 Age:overall 0.32 -0.85 1.32 1473.12 1.00 3194 155 96 7 TRUE 0.26
uterine cancer KRAS_G12V AR 51 56 Age:overall -1.58 -4.64 0.60 1162.13 1.00 891 50 55 1 TRUE 0.61
colorectal cancer KRAS_G12V GNAS 45 16 40-50yrs 0.01 -0.97 0.82 1164.95 1.00 424 44 15 1 TRUE 0.01
colorectal cancer KRAS_G12V GNAS 106 29 50-65yrs -0.04 -1.02 0.78 1209.29 1.00 943 105 28 1 TRUE 0.03
colorectal cancer KRAS_G12V GNAS 62 25 >65yrs 0.14 -0.78 1.03 1124.98 1.00 641 57 20 5 TRUE 0.12
pancreatic cancer KRAS_G12V GNAS 162 15 50-65yrs -0.22 -1.17 0.72 1392.78 1.00 461 158 11 4 TRUE 0.19
pancreatic cancer KRAS_G12V GNAS 220 42 >65yrs -0.32 -1.07 0.32 1414.84 1.00 532 211 33 9 TRUE 0.43
colorectal cancer KRAS_G12V GNAS 213 70 Age:overall 0.04 -0.89 0.84 1203.26 1.00 2008 206 63 7 TRUE 0.03
pancreatic cancer KRAS_G12V GNAS 382 57 Age:overall -0.28 -1.59 0.89 1564.11 1.00 993 369 44 13 TRUE 0.19
colorectal cancer KRAS_G12V ASXL2 42 16 40-50yrs -1.66 -2.90 -0.16 4.51 1.23 399 42 16 0 FALSE 1.34
colorectal cancer KRAS_G12V ASXL2 90 26 50-65yrs -1.64 -2.87 -0.13 4.28 1.25 858 89 25 1 FALSE 1.33
colorectal cancer KRAS_G12V ASXL2 59 20 >65yrs -1.64 -2.90 -0.09 4.35 1.24 574 58 19 1 FALSE 1.30
non-small cell lung cancer KRAS_G12V ASXL2 62 22 50-65yrs -4.88 -11.16 -0.72 385.09 1.00 1231 62 22 0 FALSE 1.13
non-small cell lung cancer KRAS_G12V ASXL2 100 36 >65yrs -4.88 -11.29 -0.70 357.86 1.00 1995 100 36 0 FALSE 1.12
colorectal cancer KRAS_G12V ASXL2 191 62 Age:overall -1.64 -2.86 -0.13 4.31 1.24 1831 189 60 2 FALSE 1.32
non-small cell lung cancer KRAS_G12V ASXL2 162 58 Age:overall -4.85 -11.15 -0.62 369.72 1.00 3226 162 58 0 FALSE 1.12
colorectal cancer KRAS_G12V SF3B1 42 16 40-50yrs -1.46 -3.35 -0.11 470.68 1.00 396 42 16 0 TRUE 1.15
colorectal cancer KRAS_G12V SF3B1 90 24 50-65yrs -1.43 -3.29 -0.08 433.94 1.00 858 89 23 1 TRUE 1.12
colorectal cancer KRAS_G12V SF3B1 59 24 >65yrs -1.42 -3.25 -0.02 417.10 1.00 574 58 23 1 TRUE 1.13
non-small cell lung cancer KRAS_G12V SF3B1 62 36 50-65yrs 0.09 -1.11 1.01 914.18 1.00 1219 60 34 2 TRUE 0.06
non-small cell lung cancer KRAS_G12V SF3B1 100 49 >65yrs 0.11 -1.02 1.03 890.84 1.00 1987 97 46 3 TRUE 0.08
colorectal cancer KRAS_G12V SF3B1 191 64 Age:overall -1.44 -3.33 -0.08 403.30 1.00 1828 189 62 2 TRUE 1.15
non-small cell lung cancer KRAS_G12V SF3B1 162 85 Age:overall 0.10 -1.07 1.07 847.22 1.00 3206 157 80 5 TRUE 0.06
colorectal cancer KRAS_G12V MLH1 106 25 50-65yrs -1.68 -4.58 0.13 95.13 1.04 948 105 24 1 TRUE 0.78
colorectal cancer KRAS_G12V MLH1 62 12 >65yrs -1.84 -5.00 0.09 94.94 1.05 649 62 12 0 TRUE 0.76
colorectal cancer KRAS_G12V MLH1 168 37 Age:overall -1.72 -4.61 0.19 97.33 1.04 1597 167 36 1 TRUE 0.74
colorectal cancer KRAS_G12V ROS1 42 19 40-50yrs -2.64 -5.52 -0.90 469.86 1.00 392 42 19 0 TRUE 1.56
colorectal cancer KRAS_G12V ROS1 90 43 50-65yrs -2.63 -5.47 -0.94 492.36 1.00 844 89 42 1 TRUE 1.57
colorectal cancer KRAS_G12V ROS1 59 31 >65yrs -2.65 -5.48 -0.93 459.25 1.00 564 59 31 0 TRUE 1.58
non-small cell lung cancer KRAS_G12V ROS1 62 37 50-65yrs -5.50 -11.22 -1.15 569.66 1.01 1216 62 37 0 TRUE 1.49
non-small cell lung cancer KRAS_G12V ROS1 100 66 >65yrs -5.50 -11.26 -1.29 496.74 1.00 1967 100 66 0 TRUE 1.51
uterine cancer KRAS_G12V ROS1 7 16 40-50yrs -1.44 -3.66 0.17 1171.44 1.00 76 7 16 0 TRUE 0.80
uterine cancer KRAS_G12V ROS1 34 45 50-65yrs -1.32 -3.15 0.06 1008.88 1.00 457 33 44 1 TRUE 0.95
uterine cancer KRAS_G12V ROS1 17 34 >65yrs -1.15 -3.13 0.44 1035.60 1.00 441 16 33 1 TRUE 0.69
colorectal cancer KRAS_G12V ROS1 191 93 Age:overall -2.64 -5.48 -0.92 477.30 1.00 1800 190 92 1 TRUE 1.58
non-small cell lung cancer KRAS_G12V ROS1 162 103 Age:overall -5.48 -11.32 -1.22 506.42 1.01 3183 162 103 0 TRUE 1.50
uterine cancer KRAS_G12V ROS1 58 95 Age:overall -1.30 -3.22 0.27 1155.36 1.00 974 56 93 2 TRUE 0.85
colorectal cancer KRAS_G12V PIK3R2 42 11 40-50yrs -0.92 -2.69 0.40 892.28 1.00 400 41 10 1 FALSE 0.59
colorectal cancer KRAS_G12V PIK3R2 90 13 50-65yrs -0.95 -2.73 0.38 871.41 1.00 865 89 12 1 FALSE 0.62
colorectal cancer KRAS_G12V PIK3R2 59 21 >65yrs -1.09 -3.08 0.26 687.13 1.00 571 59 21 0 FALSE 0.70
colorectal cancer KRAS_G12V PIK3R2 191 45 Age:overall -0.99 -2.77 0.32 705.30 1.00 1836 189 43 2 FALSE 0.68
colorectal cancer KRAS_G12V FLT3 106 17 50-65yrs -0.80 -2.67 0.60 1342.11 1.00 954 105 16 1 TRUE 0.46
colorectal cancer KRAS_G12V FLT3 62 17 >65yrs -0.77 -2.51 0.69 1268.74 1.00 644 61 16 1 TRUE 0.43
non-small cell lung cancer KRAS_G12V FLT3 63 31 50-65yrs -0.02 -1.23 1.10 777.06 1.00 1284 61 29 2 TRUE 0.01
non-small cell lung cancer KRAS_G12V FLT3 106 44 >65yrs -0.05 -1.26 0.91 734.33 1.01 2037 104 42 2 TRUE 0.03
uterine cancer KRAS_G12V FLT3 8 16 40-50yrs -5.18 -11.79 -0.75 619.52 1.00 78 8 16 0 TRUE 1.10
uterine cancer KRAS_G12V FLT3 39 23 50-65yrs -5.21 -12.10 -0.61 702.63 1.00 522 39 23 0 TRUE 1.10
uterine cancer KRAS_G12V FLT3 19 17 >65yrs -5.20 -11.81 -0.44 647.14 1.00 486 19 17 0 TRUE 1.08
colorectal cancer KRAS_G12V FLT3 168 34 Age:overall -0.78 -2.70 0.77 1292.69 1.00 1598 166 32 2 TRUE 0.42
non-small cell lung cancer KRAS_G12V FLT3 169 75 Age:overall -0.03 -1.23 1.06 746.82 1.01 3321 165 71 4 TRUE 0.02
uterine cancer KRAS_G12V FLT3 66 56 Age:overall -5.11 -11.51 -0.59 627.45 1.00 1086 66 56 0 TRUE 1.14
colorectal cancer KRAS_G12V MSH2 43 24 40-50yrs -0.57 -1.80 0.50 754.97 1.00 396 40 21 3 TRUE 0.48
colorectal cancer KRAS_G12V MSH2 90 26 50-65yrs -0.74 -1.99 0.26 736.62 1.00 856 89 25 1 TRUE 0.67
colorectal cancer KRAS_G12V MSH2 59 23 >65yrs -0.79 -2.16 0.20 697.04 1.00 574 59 23 0 TRUE 0.68
non-small cell lung cancer KRAS_G12V MSH2 62 18 50-65yrs -0.39 -2.27 1.10 457.11 1.01 1237 61 17 1 TRUE 0.18
non-small cell lung cancer KRAS_G12V MSH2 100 37 >65yrs -0.46 -2.46 0.94 399.91 1.01 1995 99 36 1 TRUE 0.22
uterine cancer KRAS_G12V MSH2 34 41 50-65yrs -1.73 -4.67 0.16 1527.88 1.00 452 33 40 1 TRUE 0.80
uterine cancer KRAS_G12V MSH2 17 16 >65yrs -2.14 -6.36 0.44 1372.29 1.00 444 17 16 0 TRUE 0.64
colorectal cancer KRAS_G12V MSH2 192 73 Age:overall -0.69 -1.88 0.28 674.21 1.00 1826 188 69 4 TRUE 0.64
non-small cell lung cancer KRAS_G12V MSH2 162 55 Age:overall -0.43 -2.44 1.12 418.30 1.01 3232 160 53 2 TRUE 0.20
uterine cancer KRAS_G12V MSH2 51 57 Age:overall -1.89 -5.17 0.60 1423.87 1.00 896 50 56 1 TRUE 0.69
non-small cell lung cancer KRAS_G12V DIS3 62 27 50-65yrs 0.32 -1.01 1.47 1292.86 1.00 1229 59 24 3 FALSE 0.22
non-small cell lung cancer KRAS_G12V DIS3 100 34 >65yrs 0.06 -1.29 1.10 794.30 1.00 1997 99 33 1 FALSE 0.03
non-small cell lung cancer KRAS_G12V DIS3 162 61 Age:overall 0.19 -1.24 1.31 1098.00 1.00 3226 158 57 4 FALSE 0.11
colorectal cancer KRAS_G12V AXL 13 13 <40yrs -1.68 -3.42 -0.36 521.92 1.01 194 13 13 0 FALSE 1.45
colorectal cancer KRAS_G12V AXL 42 16 40-50yrs -1.64 -3.28 -0.32 581.06 1.01 397 41 15 1 FALSE 1.45
colorectal cancer KRAS_G12V AXL 90 30 50-65yrs -1.70 -3.44 -0.40 510.94 1.01 852 90 30 0 FALSE 1.51
colorectal cancer KRAS_G12V AXL 59 29 >65yrs -1.66 -3.36 -0.37 478.29 1.01 565 58 28 1 FALSE 1.46
colorectal cancer KRAS_G12V AXL 204 88 Age:overall -1.67 -3.38 -0.41 497.08 1.01 2008 202 86 2 FALSE 1.51
pancreatic cancer KRAS_G12V DAXX 147 23 50-65yrs -2.33 -5.40 -0.79 1380.45 1.00 421 147 23 0 TRUE 1.23
pancreatic cancer KRAS_G12V DAXX 213 21 >65yrs -1.60 -3.17 -0.38 1170.37 1.00 504 210 18 3 TRUE 1.69
pancreatic cancer KRAS_G12V DAXX 360 44 Age:overall -1.92 -4.02 -0.44 1180.24 1.00 925 357 41 3 TRUE 1.41
colorectal cancer KRAS_G12V PIK3CG 42 22 40-50yrs -0.37 -1.31 0.45 664.19 1.01 393 40 20 2 FALSE 0.37
colorectal cancer KRAS_G12V PIK3CG 90 37 50-65yrs -0.41 -1.32 0.38 562.51 1.01 848 88 35 2 FALSE 0.44
colorectal cancer KRAS_G12V PIK3CG 59 42 >65yrs -0.37 -1.29 0.45 562.23 1.01 554 56 39 3 FALSE 0.39
non-small cell lung cancer KRAS_G12V PIK3CG 62 69 50-65yrs 0.06 -0.79 0.76 302.07 1.00 1193 59 66 3 FALSE 0.06
non-small cell lung cancer KRAS_G12V PIK3CG 100 105 >65yrs 0.10 -0.72 0.78 290.33 1.01 1942 94 99 6 FALSE 0.10
uterine cancer KRAS_G12V PIK3CG 34 28 50-65yrs -1.86 -5.25 0.28 1345.48 1.00 456 34 28 0 FALSE 0.71
uterine cancer KRAS_G12V PIK3CG 17 16 >65yrs -0.86 -3.76 1.46 1384.02 1.00 445 16 15 1 FALSE 0.29
colorectal cancer KRAS_G12V PIK3CG 191 101 Age:overall -0.38 -1.26 0.38 585.97 1.01 1795 184 94 7 FALSE 0.41
non-small cell lung cancer KRAS_G12V PIK3CG 162 174 Age:overall 0.08 -0.80 0.81 334.76 1.00 3135 153 165 9 FALSE 0.07
uterine cancer KRAS_G12V PIK3CG 51 44 Age:overall -1.34 -4.38 1.17 1508.75 1.00 901 50 43 1 FALSE 0.47
colorectal cancer KRAS_G12V MAP2K4 42 11 40-50yrs -2.18 -4.75 -0.40 1308.60 1.00 398 41 10 1 TRUE 1.22
colorectal cancer KRAS_G12V MAP2K4 90 29 50-65yrs -2.21 -4.79 -0.40 1103.17 1.00 850 90 29 0 TRUE 1.24
colorectal cancer KRAS_G12V MAP2K4 59 18 >65yrs -2.21 -4.83 -0.46 1144.61 1.00 573 59 18 0 TRUE 1.24
colorectal cancer KRAS_G12V MAP2K4 191 58 Age:overall -2.20 -4.79 -0.45 1239.94 1.00 1821 190 57 1 TRUE 1.25
colorectal cancer KRAS_G12V EGFR 45 12 40-50yrs -0.89 -2.35 0.24 534.10 1.01 428 45 12 0 TRUE 0.73
colorectal cancer KRAS_G12V EGFR 106 27 50-65yrs -0.93 -2.46 0.18 481.93 1.00 943 106 27 0 TRUE 0.78
colorectal cancer KRAS_G12V EGFR 62 23 >65yrs -0.78 -2.22 0.36 493.14 1.00 642 59 20 3 TRUE 0.63
non-small cell lung cancer KRAS_G12V EGFR 6 68 40-50yrs -3.63 -5.40 -2.25 966.33 1.00 141 6 68 0 TRUE 5.15
non-small cell lung cancer KRAS_G12V EGFR 63 403 50-65yrs -3.61 -5.39 -2.35 935.66 1.00 971 62 402 1 TRUE 5.50
non-small cell lung cancer KRAS_G12V EGFR 106 550 >65yrs -3.64 -5.38 -2.42 898.75 1.00 1634 105 549 1 TRUE 5.74
colorectal cancer KRAS_G12V EGFR 213 62 Age:overall -0.87 -2.38 0.20 608.66 1.00 2013 210 59 3 TRUE 0.73
non-small cell lung cancer KRAS_G12V EGFR 176 1042 Age:overall -3.63 -5.37 -2.37 881.39 1.00 2792 174 1040 2 TRUE 5.66
colorectal cancer KRAS_G12V ARID1B 13 11 <40yrs -1.39 -2.64 -0.29 1187.37 1.00 197 13 11 0 TRUE 1.66
colorectal cancer KRAS_G12V ARID1B 42 22 40-50yrs -1.36 -2.66 -0.29 1216.10 1.00 394 41 21 1 TRUE 1.67
colorectal cancer KRAS_G12V ARID1B 90 54 50-65yrs -1.28 -2.48 -0.29 1133.15 1.00 834 87 51 3 TRUE 1.66
colorectal cancer KRAS_G12V ARID1B 59 53 >65yrs -1.46 -2.83 -0.38 1022.24 1.00 541 59 53 0 TRUE 1.83
non-small cell lung cancer KRAS_G12V ARID1B 62 43 50-65yrs 0.13 -0.90 0.98 1010.65 1.00 1215 59 40 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V ARID1B 101 64 >65yrs 0.06 -0.97 0.89 824.56 1.00 1970 98 61 3 TRUE 0.04
uterine cancer KRAS_G12V ARID1B 7 13 40-50yrs -0.33 -1.80 0.91 1496.05 1.00 74 6 12 1 TRUE 0.21
uterine cancer KRAS_G12V ARID1B 35 58 50-65yrs -0.24 -1.32 0.68 1381.26 1.00 440 31 54 4 TRUE 0.19
uterine cancer KRAS_G12V ARID1B 17 39 >65yrs -0.57 -2.31 0.56 1297.94 1.00 423 17 39 0 TRUE 0.39
colorectal cancer KRAS_G12V ARID1B 204 140 Age:overall -1.37 -2.56 -0.38 1203.00 1.00 1966 200 136 4 TRUE 1.86
non-small cell lung cancer KRAS_G12V ARID1B 163 107 Age:overall 0.08 -1.00 0.98 1011.67 1.00 3185 157 101 6 TRUE 0.06
uterine cancer KRAS_G12V ARID1B 59 110 Age:overall -0.39 -1.67 0.64 1474.55 1.00 937 54 105 5 TRUE 0.29
non-small cell lung cancer KRAS_G12V INSR 62 23 50-65yrs -1.17 -4.01 0.69 937.05 1.00 1228 61 22 1 FALSE 0.47
non-small cell lung cancer KRAS_G12V INSR 100 28 >65yrs -1.43 -4.78 0.49 870.79 1.00 1993 100 28 0 FALSE 0.52
uterine cancer KRAS_G12V INSR 32 29 50-65yrs -1.97 -6.02 0.26 1152.59 1.00 439 32 29 0 FALSE 0.59
uterine cancer KRAS_G12V INSR 17 14 >65yrs -0.87 -3.81 1.49 1353.87 1.00 423 16 13 1 FALSE 0.29
non-small cell lung cancer KRAS_G12V INSR 162 51 Age:overall -1.27 -4.31 0.61 1010.89 1.00 3221 161 50 1 FALSE 0.51
uterine cancer KRAS_G12V INSR 49 43 Age:overall -1.37 -4.51 1.20 1361.83 1.00 862 48 42 1 FALSE 0.45
non-small cell lung cancer KRAS_G12V NKX2-1 63 31 50-65yrs 1.17 0.21 1.90 1070.20 1.00 1227 60 28 3 TRUE 2.14
non-small cell lung cancer KRAS_G12V NKX2-1 102 42 >65yrs 1.33 0.59 2.02 860.01 1.00 1999 94 34 8 TRUE 3.39
non-small cell lung cancer KRAS_G12V NKX2-1 165 73 Age:overall 1.25 0.33 2.01 1057.10 1.00 3226 154 62 11 TRUE 2.29
colorectal cancer KRAS_G12V ARID5B 42 20 40-50yrs -2.16 -4.86 -0.20 244.58 1.01 398 41 19 1 FALSE 1.14
colorectal cancer KRAS_G12V ARID5B 90 22 50-65yrs -2.27 -5.01 -0.35 264.45 1.01 857 90 22 0 FALSE 1.23
colorectal cancer KRAS_G12V ARID5B 59 17 >65yrs -2.26 -5.00 -0.19 265.16 1.01 575 59 17 0 FALSE 1.21
uterine cancer KRAS_G12V ARID5B 7 14 40-50yrs -0.88 -3.05 1.00 1427.12 1.00 74 6 13 1 FALSE 0.41
uterine cancer KRAS_G12V ARID5B 34 44 50-65yrs -1.62 -4.20 -0.01 1583.14 1.00 445 34 44 0 FALSE 0.86
uterine cancer KRAS_G12V ARID5B 17 20 >65yrs -0.84 -3.10 1.03 1526.10 1.00 440 16 19 1 FALSE 0.38
colorectal cancer KRAS_G12V ARID5B 191 59 Age:overall -2.22 -4.88 -0.24 259.56 1.01 1830 190 58 1 FALSE 1.20
uterine cancer KRAS_G12V ARID5B 58 78 Age:overall -1.09 -3.25 0.68 1430.10 1.00 959 56 76 2 FALSE 0.58
non-small cell lung cancer KRAS_G12V WT1 62 30 50-65yrs -0.60 -3.26 0.76 509.65 1.01 1223 62 30 0 TRUE 0.22
non-small cell lung cancer KRAS_G12V WT1 100 36 >65yrs -0.01 -1.50 1.12 1177.65 1.00 1999 97 33 3 TRUE 0.01
non-small cell lung cancer KRAS_G12V WT1 162 66 Age:overall -0.28 -2.39 1.06 912.25 1.00 3222 159 63 3 TRUE 0.13
non-small cell lung cancer KRAS_G12V MET 63 48 50-65yrs -0.19 -1.28 0.88 1307.17 1.00 1272 60 45 3 TRUE 0.14
non-small cell lung cancer KRAS_G12V MET 106 111 >65yrs -0.45 -1.59 0.40 1308.74 1.00 1978 103 108 3 TRUE 0.44
uterine cancer KRAS_G12V MET 39 29 50-65yrs -5.08 -12.22 -0.78 1192.93 1.00 518 39 29 0 TRUE 1.04
uterine cancer KRAS_G12V MET 19 20 >65yrs -5.04 -12.19 -0.45 1142.68 1.00 485 19 20 0 TRUE 0.97
non-small cell lung cancer KRAS_G12V MET 169 159 Age:overall -0.33 -1.56 0.83 1354.94 1.00 3250 163 153 6 TRUE 0.24
uterine cancer KRAS_G12V MET 58 49 Age:overall -4.94 -12.01 -0.55 1168.20 1.00 1003 58 49 0 TRUE 1.01
non-small cell lung cancer KRAS_G12V PMS1 62 17 50-65yrs 0.78 -0.57 1.77 597.88 1.01 1237 61 16 1 TRUE 0.69
non-small cell lung cancer KRAS_G12V PMS1 100 35 >65yrs 0.98 0.04 1.82 624.62 1.01 1999 95 30 5 TRUE 1.40
non-small cell lung cancer KRAS_G12V PMS1 162 52 Age:overall 0.89 -0.27 1.87 765.04 1.00 3236 156 46 6 TRUE 0.86
pancreatic cancer KRAS_G12V MEN1 157 39 50-65yrs -3.82 -6.88 -1.93 1415.17 1.00 421 157 39 0 TRUE 2.38
pancreatic cancer KRAS_G12V MEN1 215 28 >65yrs -3.48 -6.26 -1.66 1327.86 1.00 516 214 27 1 TRUE 2.55
pancreatic cancer KRAS_G12V MEN1 372 67 Age:overall -3.57 -6.55 -1.58 1379.81 1.00 937 371 66 1 TRUE 2.49
non-small cell lung cancer KRAS_G12V PIK3C3 62 29 50-65yrs -0.33 -3.03 1.00 757.99 1.00 1219 62 29 0 FALSE 0.12
non-small cell lung cancer KRAS_G12V PIK3C3 100 44 >65yrs 0.15 -0.95 1.24 548.94 1.01 1982 96 40 4 FALSE 0.11
non-small cell lung cancer KRAS_G12V PIK3C3 162 73 Age:overall -0.07 -1.84 1.19 1003.17 1.00 3201 158 69 4 FALSE 0.03
colorectal cancer KRAS_G12V BRAF 13 21 <40yrs -1.85 -3.22 -0.44 1461.88 1.00 204 12 20 1 TRUE 2.11
colorectal cancer KRAS_G12V BRAF 45 34 40-50yrs -1.77 -3.13 -0.50 1410.71 1.00 409 43 32 2 TRUE 2.05
colorectal cancer KRAS_G12V BRAF 106 93 50-65yrs -2.07 -3.34 -1.01 1368.71 1.00 878 105 92 1 TRUE 3.27
colorectal cancer KRAS_G12V BRAF 62 105 >65yrs -2.18 -3.51 -1.10 1374.21 1.00 562 62 105 0 TRUE 3.18
non-small cell lung cancer KRAS_G12V BRAF 63 62 50-65yrs -0.14 -0.98 0.64 1128.82 1.00 1252 60 59 3 TRUE 0.13
non-small cell lung cancer KRAS_G12V BRAF 106 122 >65yrs -0.19 -0.99 0.53 1059.88 1.00 1962 101 117 5 TRUE 0.20
colorectal cancer KRAS_G12V BRAF 226 253 Age:overall -1.96 -3.19 -0.87 1471.86 1.00 2053 222 249 4 TRUE 3.09
non-small cell lung cancer KRAS_G12V BRAF 169 184 Age:overall -0.18 -1.10 0.64 1282.18 1.00 3214 161 176 8 TRUE 0.15
colorectal cancer KRAS_G12V B2M 12 12 <40yrs -2.22 -4.01 -0.77 290.28 1.01 188 12 12 0 FALSE 2.13
colorectal cancer KRAS_G12V B2M 41 21 40-50yrs -2.25 -4.04 -0.88 335.86 1.00 384 41 21 0 FALSE 2.16
colorectal cancer KRAS_G12V B2M 86 52 50-65yrs -2.15 -3.78 -0.77 286.27 1.01 821 84 50 2 FALSE 2.12
colorectal cancer KRAS_G12V B2M 55 54 >65yrs -2.27 -4.04 -0.91 404.48 1.01 546 55 54 0 FALSE 2.27
colorectal cancer KRAS_G12V B2M 194 139 Age:overall -2.23 -3.92 -0.87 297.40 1.00 1939 192 137 2 FALSE 2.28
colorectal cancer KRAS_G12V TGFBR1 12 11 <40yrs 0.28 -1.15 1.71 1167.68 1.00 191 10 9 2 FALSE 0.16
colorectal cancer KRAS_G12V TGFBR1 86 18 50-65yrs 0.00 -1.31 1.12 1156.16 1.00 840 84 16 2 FALSE 0.00
colorectal cancer KRAS_G12V TGFBR1 55 13 >65yrs -0.29 -1.97 0.94 1159.94 1.00 565 55 13 0 FALSE 0.15
non-small cell lung cancer KRAS_G12V TGFBR1 62 16 50-65yrs -0.16 -1.84 1.51 218.09 1.02 1233 60 14 2 FALSE 0.07
non-small cell lung cancer KRAS_G12V TGFBR1 100 31 >65yrs -0.76 -4.01 0.78 886.89 1.00 1990 100 31 0 FALSE 0.28
colorectal cancer KRAS_G12V TGFBR1 153 42 Age:overall 0.02 -1.36 1.18 1306.04 1.00 1596 149 38 4 FALSE 0.01
non-small cell lung cancer KRAS_G12V TGFBR1 162 47 Age:overall -0.44 -2.42 1.13 699.73 1.00 3223 160 45 2 FALSE 0.19
colorectal cancer KRAS_G12V TET2 13 16 <40yrs -1.54 -3.36 -0.26 111.02 1.03 194 12 15 1 TRUE 1.21
colorectal cancer KRAS_G12V TET2 42 19 40-50yrs -1.55 -3.34 -0.22 113.08 1.03 395 41 18 1 TRUE 1.22
colorectal cancer KRAS_G12V TET2 90 29 50-65yrs -1.63 -3.46 -0.32 96.19 1.03 851 90 29 0 TRUE 1.33
colorectal cancer KRAS_G12V TET2 59 27 >65yrs -1.62 -3.48 -0.34 85.74 1.03 568 59 27 0 TRUE 1.31
non-small cell lung cancer KRAS_G12V TET2 62 33 50-65yrs -0.85 -2.66 0.53 483.73 1.00 1224 61 32 1 TRUE 0.51
non-small cell lung cancer KRAS_G12V TET2 100 45 >65yrs -0.87 -2.66 0.46 547.36 1.00 1986 99 44 1 TRUE 0.52
uterine cancer KRAS_G12V TET2 7 11 40-50yrs -1.94 -5.05 0.08 1073.85 1.00 77 7 11 0 TRUE 0.84
uterine cancer KRAS_G12V TET2 34 30 50-65yrs -1.71 -4.66 0.04 1233.05 1.00 456 33 29 1 TRUE 0.82
uterine cancer KRAS_G12V TET2 17 22 >65yrs -1.97 -5.13 0.13 1047.14 1.00 438 17 22 0 TRUE 0.84
colorectal cancer KRAS_G12V TET2 204 91 Age:overall -1.59 -3.36 -0.33 94.04 1.03 2008 202 89 2 TRUE 1.32
non-small cell lung cancer KRAS_G12V TET2 162 78 Age:overall -0.86 -2.69 0.53 574.62 1.00 3210 160 76 2 TRUE 0.50
uterine cancer KRAS_G12V TET2 58 63 Age:overall -1.86 -4.96 0.08 1070.59 1.00 971 57 62 1 TRUE 0.86
colorectal cancer KRAS_G12V PDGFRB 42 11 40-50yrs -1.82 -4.60 0.34 857.11 1.00 398 41 10 1 TRUE 0.85
colorectal cancer KRAS_G12V PDGFRB 90 11 50-65yrs -2.06 -4.90 0.02 838.63 1.00 866 90 11 0 TRUE 1.00
colorectal cancer KRAS_G12V PDGFRB 59 24 >65yrs -2.14 -4.98 -0.04 814.30 1.00 566 59 24 0 TRUE 1.06
non-small cell lung cancer KRAS_G12V PDGFRB 62 33 50-65yrs 0.54 -0.32 1.37 136.93 1.03 1226 59 30 3 TRUE 0.67
non-small cell lung cancer KRAS_G12V PDGFRB 101 55 >65yrs 0.50 -0.40 1.25 89.08 1.04 1982 97 51 4 TRUE 0.62
colorectal cancer KRAS_G12V PDGFRB 191 46 Age:overall -2.00 -4.82 0.04 815.10 1.00 1830 190 45 1 TRUE 1.01
non-small cell lung cancer KRAS_G12V PDGFRB 163 88 Age:overall 0.52 -0.40 1.39 171.20 1.03 3208 156 81 7 TRUE 0.59
colorectal cancer KRAS_G12V CARD11 13 21 <40yrs -0.99 -2.11 0.05 1076.03 1.00 186 12 20 1 FALSE 1.09
colorectal cancer KRAS_G12V CARD11 42 20 40-50yrs -1.08 -2.21 -0.09 1047.72 1.00 390 42 20 0 FALSE 1.30
colorectal cancer KRAS_G12V CARD11 90 45 50-65yrs -0.95 -1.98 -0.01 930.49 1.00 839 87 42 3 FALSE 1.20
colorectal cancer KRAS_G12V CARD11 59 42 >65yrs -1.06 -2.16 -0.14 923.35 1.00 554 58 41 1 FALSE 1.36
non-small cell lung cancer KRAS_G12V CARD11 62 50 50-65yrs -0.85 -2.37 0.32 889.89 1.00 1205 61 49 1 FALSE 0.64
non-small cell lung cancer KRAS_G12V CARD11 100 75 >65yrs -0.83 -2.30 0.30 945.71 1.00 1961 98 73 2 FALSE 0.65
uterine cancer KRAS_G12V CARD11 34 26 50-65yrs -0.60 -2.67 0.88 965.75 1.00 457 33 25 1 FALSE 0.29
uterine cancer KRAS_G12V CARD11 17 23 >65yrs -0.45 -2.65 1.18 1029.76 1.00 438 16 22 1 FALSE 0.20
colorectal cancer KRAS_G12V CARD11 204 128 Age:overall -1.02 -2.06 -0.09 866.40 1.00 1969 199 123 5 FALSE 1.35
non-small cell lung cancer KRAS_G12V CARD11 162 125 Age:overall -0.83 -2.43 0.35 1014.65 1.00 3166 159 122 3 FALSE 0.60
uterine cancer KRAS_G12V CARD11 51 49 Age:overall -0.52 -2.71 1.22 1130.25 1.00 895 49 47 2 FALSE 0.21
colorectal cancer KRAS_G12V DNMT3A 42 11 40-50yrs -2.11 -5.27 -0.26 312.65 1.01 399 42 11 0 TRUE 1.03
colorectal cancer KRAS_G12V DNMT3A 90 21 50-65yrs -2.12 -5.23 -0.32 303.36 1.01 857 90 21 0 TRUE 1.05
colorectal cancer KRAS_G12V DNMT3A 59 19 >65yrs -2.06 -5.24 -0.22 303.60 1.01 576 58 18 1 TRUE 1.00
non-small cell lung cancer KRAS_G12V DNMT3A 62 30 50-65yrs 0.29 -0.83 1.28 358.96 1.01 1225 60 28 2 TRUE 0.22
non-small cell lung cancer KRAS_G12V DNMT3A 100 42 >65yrs 0.30 -0.79 1.26 302.24 1.01 1990 97 39 3 TRUE 0.24
colorectal cancer KRAS_G12V DNMT3A 191 51 Age:overall -2.10 -5.23 -0.30 312.30 1.01 1832 190 50 1 TRUE 1.03
non-small cell lung cancer KRAS_G12V DNMT3A 162 72 Age:overall 0.29 -0.83 1.30 387.23 1.01 3215 157 67 5 TRUE 0.22
colorectal cancer KRAS_G12V MSH6 13 12 <40yrs -1.34 -2.72 -0.26 1175.96 1.00 193 13 12 0 TRUE 1.53
colorectal cancer KRAS_G12V MSH6 42 24 40-50yrs -1.29 -2.67 -0.19 1403.85 1.00 391 40 22 2 TRUE 1.43
colorectal cancer KRAS_G12V MSH6 90 38 50-65yrs -1.36 -2.77 -0.31 1366.08 1.00 849 90 38 0 TRUE 1.56
colorectal cancer KRAS_G12V MSH6 59 26 >65yrs -1.32 -2.73 -0.26 1242.92 1.00 568 58 25 1 TRUE 1.48
uterine cancer KRAS_G12V MSH6 7 13 40-50yrs 0.09 -1.42 1.58 1349.45 1.00 74 5 11 2 TRUE 0.04
uterine cancer KRAS_G12V MSH6 34 38 50-65yrs -0.74 -2.74 0.59 1461.83 1.00 451 34 38 0 TRUE 0.42
uterine cancer KRAS_G12V MSH6 17 35 >65yrs -0.09 -1.59 1.23 1278.52 1.00 435 15 33 2 TRUE 0.05
colorectal cancer KRAS_G12V MSH6 204 100 Age:overall -1.33 -2.71 -0.28 1336.97 1.00 2001 201 97 3 TRUE 1.55
uterine cancer KRAS_G12V MSH6 58 86 Age:overall -0.25 -1.81 1.04 1456.85 1.00 960 54 82 4 TRUE 0.14
non-small cell lung cancer KRAS_G12V MAX 62 15 50-65yrs 0.00 -3.88 1.60 1095.89 1.00 1232 62 15 0 FALSE 0.00
non-small cell lung cancer KRAS_G12V MAX 100 39 >65yrs 1.01 0.05 1.87 1118.38 1.00 1989 94 33 6 FALSE 1.43
non-small cell lung cancer KRAS_G12V MAX 162 54 Age:overall 0.54 -2.05 2.04 1429.68 1.00 3221 156 48 6 FALSE 0.22
non-small cell lung cancer KRAS_G12V INPP4B 62 46 50-65yrs 0.27 -0.85 1.44 907.94 1.00 1215 57 41 5 FALSE 0.19
non-small cell lung cancer KRAS_G12V INPP4B 100 76 >65yrs -0.44 -2.20 0.62 893.73 1.01 1961 99 75 1 FALSE 0.28
non-small cell lung cancer KRAS_G12V INPP4B 162 122 Age:overall -0.10 -1.68 1.18 1195.54 1.00 3176 156 116 6 FALSE 0.05
non-small cell lung cancer KRAS_G12V NFE2L2 62 39 50-65yrs -0.03 -1.10 1.42 3.33 1.33 1220 58 35 4 FALSE 0.01
non-small cell lung cancer KRAS_G12V NFE2L2 100 85 >65yrs -1.63 -6.19 -0.04 13.00 1.09 1954 100 85 0 FALSE 0.49
non-small cell lung cancer KRAS_G12V NFE2L2 162 124 Age:overall -0.81 -3.54 1.21 1376.32 1.00 3174 158 120 4 FALSE 0.34
uterine cancer KRAS_G12V SPOP 34 25 50-65yrs -1.45 -4.50 0.47 996.92 1.00 454 33 24 1 FALSE 0.59
uterine cancer KRAS_G12V SPOP 17 26 >65yrs -1.80 -5.55 0.44 1115.79 1.00 432 17 26 0 FALSE 0.58
uterine cancer KRAS_G12V SPOP 51 51 Age:overall -1.60 -5.09 0.63 1133.29 1.00 886 50 50 1 FALSE 0.58
colorectal cancer KRAS_G12V SOX9 13 22 <40yrs 0.18 -0.40 0.69 549.84 1.00 185 12 21 1 FALSE 0.28
colorectal cancer KRAS_G12V SOX9 42 41 40-50yrs 0.21 -0.34 0.75 433.49 1.01 373 37 36 5 FALSE 0.35
colorectal cancer KRAS_G12V SOX9 92 114 50-65yrs 0.26 -0.28 0.72 249.70 1.01 792 77 99 15 FALSE 0.52
colorectal cancer KRAS_G12V SOX9 59 87 >65yrs 0.19 -0.34 0.67 351.39 1.01 517 51 79 8 FALSE 0.36
colorectal cancer KRAS_G12V SOX9 206 264 Age:overall 0.21 -0.31 0.66 338.62 1.01 1867 177 235 29 FALSE 0.40
colorectal cancer KRAS_G12V ETV1 86 15 50-65yrs -2.21 -5.72 0.02 495.99 1.00 840 86 15 0 TRUE 0.78
colorectal cancer KRAS_G12V ETV1 55 23 >65yrs -1.72 -5.36 0.33 280.67 1.01 558 54 22 1 TRUE 0.74
colorectal cancer KRAS_G12V ETV1 141 38 Age:overall -1.93 -5.36 0.31 360.76 1.01 1398 140 37 1 TRUE 0.76
colorectal cancer KRAS_G12V ARAF 90 22 50-65yrs -5.26 -11.88 -1.08 726.14 1.00 858 90 22 0 FALSE 1.17
colorectal cancer KRAS_G12V ARAF 59 23 >65yrs -5.28 -12.13 -1.10 898.02 1.00 569 59 23 0 FALSE 1.16
non-small cell lung cancer KRAS_G12V ARAF 62 26 50-65yrs -0.66 -2.34 0.60 400.02 1.01 1232 61 25 1 FALSE 0.42
non-small cell lung cancer KRAS_G12V ARAF 100 42 >65yrs -0.70 -2.40 0.51 474.84 1.01 1992 99 41 1 FALSE 0.46
colorectal cancer KRAS_G12V ARAF 149 45 Age:overall -5.20 -11.74 -1.10 735.11 1.00 1427 149 45 0 FALSE 1.17
non-small cell lung cancer KRAS_G12V ARAF 162 68 Age:overall -0.69 -2.41 0.52 481.80 1.01 3224 160 66 2 FALSE 0.43
non-small cell lung cancer KRAS_G12V JAK2 63 38 50-65yrs -0.24 -1.93 0.98 1384.33 1.00 1277 61 36 2 TRUE 0.14
non-small cell lung cancer KRAS_G12V JAK2 106 35 >65yrs -0.44 -2.06 0.82 1449.61 1.00 2043 105 34 1 TRUE 0.26
non-small cell lung cancer KRAS_G12V JAK2 169 73 Age:overall -0.32 -2.02 1.03 1331.12 1.00 3320 166 70 3 TRUE 0.17
colorectal cancer KRAS_G12V SMAD2 42 33 40-50yrs -0.04 -1.64 1.01 1249.31 1.00 383 41 32 1 TRUE 0.02
colorectal cancer KRAS_G12V SMAD2 91 39 50-65yrs 0.69 -0.09 1.40 1304.74 1.00 848 84 32 7 TRUE 1.17
colorectal cancer KRAS_G12V SMAD2 59 20 >65yrs 1.14 0.19 2.13 1219.85 1.00 577 52 13 7 TRUE 1.67
colorectal cancer KRAS_G12V SMAD2 192 92 Age:overall 0.58 -0.63 1.58 1373.32 1.00 1808 177 77 15 TRUE 0.55
non-small cell lung cancer KRAS_G12V TP63 62 31 50-65yrs -0.33 -1.90 0.88 1164.73 1.00 1218 61 30 1 FALSE 0.19
non-small cell lung cancer KRAS_G12V TP63 100 38 >65yrs -0.26 -1.74 0.92 1185.22 1.00 1986 98 36 2 FALSE 0.16
non-small cell lung cancer KRAS_G12V TP63 162 69 Age:overall -0.30 -1.83 0.96 1168.67 1.00 3204 159 66 3 FALSE 0.17
colorectal cancer KRAS_G12V JUN 41 11 40-50yrs -2.09 -4.94 -0.23 300.73 1.01 385 41 11 0 FALSE 1.04
colorectal cancer KRAS_G12V JUN 86 18 50-65yrs -2.03 -4.84 -0.25 288.71 1.01 837 85 17 1 FALSE 1.01
colorectal cancer KRAS_G12V JUN 55 19 >65yrs -2.10 -4.99 -0.30 315.31 1.01 561 55 19 0 FALSE 1.04
colorectal cancer KRAS_G12V JUN 182 48 Age:overall -2.07 -4.84 -0.27 294.39 1.01 1783 181 47 1 FALSE 1.04
colorectal cancer KRAS_G12V DNMT3B 13 12 <40yrs -0.06 -1.37 1.33 882.33 1.00 192 11 10 2 FALSE 0.03
colorectal cancer KRAS_G12V DNMT3B 86 28 50-65yrs -0.38 -1.75 0.68 557.45 1.01 827 85 27 1 FALSE 0.27
colorectal cancer KRAS_G12V DNMT3B 55 15 >65yrs -0.28 -1.62 0.78 730.33 1.01 565 54 14 1 FALSE 0.18
colorectal cancer KRAS_G12V DNMT3B 154 55 Age:overall -0.24 -1.55 0.87 702.62 1.01 1584 150 51 4 FALSE 0.16
non-small cell lung cancer KRAS_G12V MYOD1 62 21 50-65yrs 0.32 -1.03 1.37 700.85 1.00 1231 61 20 1 FALSE 0.20
non-small cell lung cancer KRAS_G12V MYOD1 100 31 >65yrs 0.42 -0.85 1.41 600.31 1.00 1993 97 28 3 FALSE 0.33
non-small cell lung cancer KRAS_G12V MYOD1 162 52 Age:overall 0.38 -0.96 1.47 614.30 1.00 3224 158 48 4 FALSE 0.26
colorectal cancer KRAS_G12V FGFR1 45 12 40-50yrs -1.92 -4.80 -0.17 1071.83 1.00 428 45 12 0 TRUE 0.94
colorectal cancer KRAS_G12V FGFR1 106 21 50-65yrs -1.87 -4.65 -0.14 1049.29 1.00 951 105 20 1 TRUE 0.96
colorectal cancer KRAS_G12V FGFR1 62 11 >65yrs -1.90 -4.70 -0.10 1051.21 1.01 649 62 11 0 TRUE 0.94
colorectal cancer KRAS_G12V FGFR1 213 44 Age:overall -1.89 -4.65 -0.20 1063.04 1.00 2028 212 43 1 TRUE 0.97
colorectal cancer KRAS_G12V MITF 90 25 50-65yrs -1.97 -4.87 -0.01 397.94 1.00 853 90 25 0 FALSE 0.86
colorectal cancer KRAS_G12V MITF 59 14 >65yrs -1.71 -4.57 0.24 252.79 1.01 577 58 13 1 FALSE 0.79
colorectal cancer KRAS_G12V MITF 149 39 Age:overall -1.82 -4.67 0.25 293.41 1.01 1430 148 38 1 FALSE 0.83
non-small cell lung cancer KRAS_G12V BTK 62 28 50-65yrs -0.12 -1.79 1.08 938.18 1.00 1226 61 27 1 TRUE 0.06
non-small cell lung cancer KRAS_G12V BTK 100 29 >65yrs 0.01 -1.41 1.12 1167.58 1.00 2002 98 27 2 TRUE 0.00
non-small cell lung cancer KRAS_G12V BTK 162 57 Age:overall -0.05 -1.63 1.28 1025.01 1.00 3228 159 54 3 TRUE 0.02
colorectal cancer KRAS_G12V SH2B3 77 25 50-65yrs -5.44 -12.06 -1.16 686.32 1.00 783 77 25 0 FALSE 1.24
colorectal cancer KRAS_G12V SH2B3 58 19 >65yrs -5.41 -12.14 -1.08 668.05 1.00 518 58 19 0 FALSE 1.22
colorectal cancer KRAS_G12V SH2B3 135 44 Age:overall -5.40 -11.98 -1.12 639.69 1.00 1301 135 44 0 FALSE 1.25
colorectal cancer KRAS_G12V GLI1 40 17 40-50yrs -1.59 -3.36 -0.24 414.26 1.01 360 39 16 1 FALSE 1.32
colorectal cancer KRAS_G12V GLI1 77 36 50-65yrs -1.64 -3.40 -0.33 479.60 1.01 771 77 36 0 FALSE 1.37
colorectal cancer KRAS_G12V GLI1 58 25 >65yrs -1.60 -3.30 -0.26 433.70 1.01 514 57 24 1 FALSE 1.34
non-small cell lung cancer KRAS_G12V GLI1 58 35 50-65yrs 0.38 -1.11 1.28 1159.39 1.00 1070 57 34 1 FALSE 0.27
non-small cell lung cancer KRAS_G12V GLI1 92 64 >65yrs 0.77 -0.08 1.51 1339.44 1.00 1819 84 56 8 FALSE 1.27
uterine cancer KRAS_G12V GLI1 6 12 40-50yrs -1.34 -4.43 0.90 1330.77 1.00 65 5 11 1 FALSE 0.51
uterine cancer KRAS_G12V GLI1 31 22 50-65yrs -1.97 -5.34 0.18 1204.31 1.00 408 31 22 0 FALSE 0.80
uterine cancer KRAS_G12V GLI1 16 18 >65yrs -1.88 -5.34 0.34 1183.06 1.00 400 16 18 0 FALSE 0.71
colorectal cancer KRAS_G12V GLI1 175 78 Age:overall -1.60 -3.34 -0.30 431.26 1.01 1645 173 76 2 FALSE 1.36
non-small cell lung cancer KRAS_G12V GLI1 150 99 Age:overall 0.57 -0.75 1.49 1701.05 1.00 2889 141 90 9 FALSE 0.47
uterine cancer KRAS_G12V GLI1 53 52 Age:overall -1.71 -4.88 0.41 1314.14 1.00 873 52 51 1 FALSE 0.73
colorectal cancer KRAS_G12V ZFHX3 14 28 <40yrs -1.14 -2.10 -0.22 1307.59 1.00 169 12 26 2 FALSE 1.72
colorectal cancer KRAS_G12V ZFHX3 40 32 40-50yrs -1.17 -2.03 -0.28 1130.24 1.00 349 38 30 2 FALSE 1.98
colorectal cancer KRAS_G12V ZFHX3 77 82 50-65yrs -1.33 -2.30 -0.48 1328.90 1.00 747 76 81 1 FALSE 2.49
colorectal cancer KRAS_G12V ZFHX3 59 84 >65yrs -1.27 -2.14 -0.48 1250.53 1.00 481 57 82 2 FALSE 2.43
non-small cell lung cancer KRAS_G12V ZFHX3 58 57 50-65yrs 0.27 -0.36 0.91 664.73 1.01 1051 54 53 4 FALSE 0.45
non-small cell lung cancer KRAS_G12V ZFHX3 93 96 >65yrs 0.29 -0.32 0.89 1078.75 1.00 1783 87 90 6 FALSE 0.51
uterine cancer KRAS_G12V ZFHX3 6 21 40-50yrs -0.43 -1.42 0.51 687.78 1.00 64 5 20 1 FALSE 0.42
uterine cancer KRAS_G12V ZFHX3 31 96 50-65yrs -0.52 -1.38 0.24 689.54 1.01 362 28 93 3 FALSE 0.67
uterine cancer KRAS_G12V ZFHX3 17 90 >65yrs -0.36 -1.20 0.52 685.32 1.00 362 13 86 4 FALSE 0.38
colorectal cancer KRAS_G12V ZFHX3 190 226 Age:overall -1.23 -2.08 -0.48 1271.67 1.00 1746 183 219 7 FALSE 2.48
non-small cell lung cancer KRAS_G12V ZFHX3 151 153 Age:overall 0.28 -0.37 0.91 1085.21 1.00 2834 141 143 10 FALSE 0.45
uterine cancer KRAS_G12V ZFHX3 54 207 Age:overall -0.43 -1.28 0.39 609.64 1.01 788 46 199 8 FALSE 0.50
colorectal cancer KRAS_G12V MST1R 73 26 50-65yrs -2.03 -4.59 0.02 601.96 1.00 757 72 25 1 FALSE 0.99
colorectal cancer KRAS_G12V MST1R 54 33 >65yrs -2.50 -5.99 -0.41 834.30 1.00 499 54 33 0 FALSE 1.04
colorectal cancer KRAS_G12V MST1R 127 59 Age:overall -2.22 -5.04 -0.12 574.45 1.01 1256 126 58 1 FALSE 1.05
colorectal cancer KRAS_G12V MGA 14 18 <40yrs -0.25 -1.15 0.59 1451.43 1.00 177 12 16 2 FALSE 0.24
colorectal cancer KRAS_G12V MGA 40 19 40-50yrs -0.43 -1.41 0.34 1314.11 1.00 357 40 19 0 FALSE 0.46
colorectal cancer KRAS_G12V MGA 77 41 50-65yrs -0.32 -1.21 0.45 1299.84 1.00 767 74 38 3 FALSE 0.36
colorectal cancer KRAS_G12V MGA 58 45 >65yrs -0.27 -1.13 0.47 1538.08 1.00 499 54 41 4 FALSE 0.30
non-small cell lung cancer KRAS_G12V MGA 58 60 50-65yrs 0.42 -0.39 1.08 1441.09 1.00 1049 54 56 4 FALSE 0.57
non-small cell lung cancer KRAS_G12V MGA 92 129 >65yrs 0.50 -0.13 1.08 1369.05 1.00 1770 82 119 10 FALSE 0.93
uterine cancer KRAS_G12V MGA 6 15 40-50yrs -1.58 -4.11 0.06 1256.30 1.00 68 6 15 0 FALSE 0.90
uterine cancer KRAS_G12V MGA 31 48 50-65yrs -1.70 -4.03 -0.13 1253.88 1.00 391 31 48 0 FALSE 1.06
uterine cancer KRAS_G12V MGA 16 47 >65yrs -1.14 -2.97 0.48 1178.40 1.01 391 14 45 2 FALSE 0.74
colorectal cancer KRAS_G12V MGA 189 123 Age:overall -0.32 -1.22 0.41 1341.49 1.00 1800 180 114 9 FALSE 0.39
non-small cell lung cancer KRAS_G12V MGA 150 189 Age:overall 0.46 -0.39 1.18 1271.01 1.00 2819 136 175 14 FALSE 0.57
uterine cancer KRAS_G12V MGA 53 110 Age:overall -1.47 -3.36 -0.03 1273.38 1.00 850 51 108 2 FALSE 1.06
colorectal cancer KRAS_G12V TCF3 40 12 40-50yrs -0.68 -2.05 0.70 841.63 1.00 351 37 9 3 FALSE 0.48
colorectal cancer KRAS_G12V TCF3 73 26 50-65yrs -0.91 -2.54 0.29 738.96 1.00 756 73 26 0 FALSE 0.67
colorectal cancer KRAS_G12V TCF3 54 22 >65yrs -0.90 -2.55 0.31 928.93 1.00 503 54 22 0 FALSE 0.62
colorectal cancer KRAS_G12V TCF3 167 60 Age:overall -0.83 -2.33 0.33 838.04 1.00 1610 164 57 3 FALSE 0.66
colorectal cancer KRAS_G12V KMT2B 9 25 <40yrs -0.72 -2.17 0.86 1481.86 1.00 90 6 22 3 FALSE 0.45
colorectal cancer KRAS_G12V KMT2B 23 17 40-50yrs -1.22 -2.68 0.25 1582.87 1.00 212 22 16 1 FALSE 0.99
colorectal cancer KRAS_G12V KMT2B 46 59 50-65yrs -1.84 -3.62 -0.59 1222.40 1.00 414 46 59 0 FALSE 1.75
colorectal cancer KRAS_G12V KMT2B 30 81 >65yrs -1.65 -3.12 -0.56 1438.23 1.00 263 29 80 1 FALSE 1.97
non-small cell lung cancer KRAS_G12V KMT2B 35 22 50-65yrs -0.19 -1.75 1.14 809.99 1.00 610 33 20 2 FALSE 0.10
non-small cell lung cancer KRAS_G12V KMT2B 54 47 >65yrs -0.46 -2.10 0.78 978.52 1.00 1030 53 46 1 FALSE 0.29
colorectal cancer KRAS_G12V KMT2B 108 182 Age:overall -1.36 -2.66 -0.16 1435.28 1.00 979 103 177 5 FALSE 1.51
non-small cell lung cancer KRAS_G12V KMT2B 89 69 Age:overall -0.31 -1.92 1.08 934.30 1.00 1640 86 66 3 FALSE 0.17
colorectal cancer KRAS_G12V TCF7L2 13 34 <40yrs -0.01 -0.51 0.50 635.62 1.00 160 10 31 3 FALSE 0.01
colorectal cancer KRAS_G12V TCF7L2 42 56 40-50yrs 0.02 -0.46 0.53 633.84 1.00 327 34 48 8 FALSE 0.02
colorectal cancer KRAS_G12V TCF7L2 78 121 50-65yrs -0.03 -0.52 0.45 545.30 1.00 704 69 112 9 FALSE 0.04
colorectal cancer KRAS_G12V TCF7L2 59 88 >65yrs -0.03 -0.51 0.44 615.53 1.00 459 52 81 7 FALSE 0.04
colorectal cancer KRAS_G12V TCF7L2 192 299 Age:overall -0.01 -0.48 0.44 567.89 1.00 1650 165 272 27 FALSE 0.02
colorectal cancer KRAS_G12V MSH3 7 12 <40yrs -5.65 -12.08 -1.74 244.06 1.02 94 7 12 0 FALSE 1.30
colorectal cancer KRAS_G12V MSH3 46 31 50-65yrs -5.67 -12.23 -1.73 247.22 1.02 423 46 31 0 FALSE 1.31
colorectal cancer KRAS_G12V MSH3 30 39 >65yrs -5.67 -12.26 -1.80 241.88 1.02 281 30 39 0 FALSE 1.30
colorectal cancer KRAS_G12V MSH3 83 82 Age:overall -5.66 -12.27 -1.72 238.94 1.02 798 83 82 0 FALSE 1.32
colorectal cancer KRAS_G12V ANKRD11 12 21 <40yrs -1.76 -3.33 -0.62 817.61 1.01 166 12 21 0 FALSE 1.84
colorectal cancer KRAS_G12V ANKRD11 39 14 40-50yrs -1.64 -3.20 -0.42 1030.69 1.00 349 38 13 1 FALSE 1.62
colorectal cancer KRAS_G12V ANKRD11 73 61 50-65yrs -1.74 -3.24 -0.63 841.17 1.01 739 72 60 1 FALSE 2.08
colorectal cancer KRAS_G12V ANKRD11 54 50 >65yrs -1.72 -3.20 -0.60 750.56 1.00 482 53 49 1 FALSE 2.01
non-small cell lung cancer KRAS_G12V ANKRD11 58 21 50-65yrs -0.90 -2.56 0.62 35.28 1.06 1076 57 20 1 FALSE 0.53
non-small cell lung cancer KRAS_G12V ANKRD11 92 50 >65yrs -0.98 -2.58 0.43 41.24 1.05 1818 91 49 1 FALSE 0.66
uterine cancer KRAS_G12V ANKRD11 29 37 50-65yrs -0.66 -2.28 0.65 1439.82 1.00 378 28 36 1 FALSE 0.43
uterine cancer KRAS_G12V ANKRD11 16 42 >65yrs -0.37 -2.01 0.94 1520.37 1.00 367 14 40 2 FALSE 0.21
colorectal cancer KRAS_G12V ANKRD11 178 146 Age:overall -1.72 -3.15 -0.62 731.26 1.01 1736 175 143 3 FALSE 2.11
non-small cell lung cancer KRAS_G12V ANKRD11 150 71 Age:overall -0.94 -2.74 0.66 44.97 1.05 2894 148 69 2 FALSE 0.54
uterine cancer KRAS_G12V ANKRD11 45 79 Age:overall -0.51 -2.20 0.97 1390.93 1.00 745 42 76 3 FALSE 0.28
colorectal cancer KRAS_G12V PGR 73 24 50-65yrs -2.11 -5.33 -0.32 301.40 1.02 758 73 24 0 FALSE 0.99
colorectal cancer KRAS_G12V PGR 54 24 >65yrs -1.84 -4.43 -0.13 458.86 1.01 501 53 23 1 FALSE 1.02
non-small cell lung cancer KRAS_G12V PGR 58 35 50-65yrs -5.30 -11.79 -1.24 394.24 1.00 1063 58 35 0 FALSE 1.25
non-small cell lung cancer KRAS_G12V PGR 92 49 >65yrs -5.30 -11.80 -1.26 396.86 1.00 1815 92 49 0 FALSE 1.25
uterine cancer KRAS_G12V PGR 29 25 50-65yrs -1.33 -4.00 0.63 871.54 1.01 384 28 24 1 FALSE 0.57
uterine cancer KRAS_G12V PGR 16 16 >65yrs -1.64 -4.90 0.74 1250.87 1.00 378 16 16 0 FALSE 0.57
colorectal cancer KRAS_G12V PGR 127 48 Age:overall -1.96 -4.88 -0.14 384.07 1.01 1259 126 47 1 FALSE 1.01
non-small cell lung cancer KRAS_G12V PGR 150 84 Age:overall -5.24 -11.66 -1.05 406.33 1.00 2878 150 84 0 FALSE 1.25
uterine cancer KRAS_G12V PGR 45 41 Age:overall -1.46 -4.47 0.76 1049.07 1.01 762 44 40 1 FALSE 0.55
colorectal cancer KRAS_G12V PLCG2 39 14 40-50yrs -1.66 -3.55 -0.18 1360.17 1.00 347 39 14 0 FALSE 1.24
colorectal cancer KRAS_G12V PLCG2 73 27 50-65yrs -1.55 -3.32 -0.14 1212.82 1.00 757 72 26 1 FALSE 1.22
colorectal cancer KRAS_G12V PLCG2 54 35 >65yrs -1.58 -3.36 -0.25 1232.21 1.00 492 53 34 1 FALSE 1.30
non-small cell lung cancer KRAS_G12V PLCG2 58 13 50-65yrs -1.72 -5.30 0.44 1053.53 1.00 1084 58 13 0 FALSE 0.59
non-small cell lung cancer KRAS_G12V PLCG2 92 43 >65yrs -1.46 -4.34 0.38 838.21 1.00 1826 91 42 1 FALSE 0.64
uterine cancer KRAS_G12V PLCG2 29 30 50-65yrs -4.84 -11.33 -0.75 463.77 1.01 385 29 30 0 FALSE 1.02
uterine cancer KRAS_G12V PLCG2 16 16 >65yrs -4.77 -11.51 -0.69 690.51 1.00 380 16 16 0 FALSE 1.00
colorectal cancer KRAS_G12V PLCG2 166 76 Age:overall -1.60 -3.35 -0.21 1286.73 1.00 1596 164 74 2 FALSE 1.28
non-small cell lung cancer KRAS_G12V PLCG2 150 56 Age:overall -1.56 -4.79 0.60 951.33 1.00 2910 149 55 1 FALSE 0.61
uterine cancer KRAS_G12V PLCG2 45 46 Age:overall -4.70 -11.28 -0.63 519.98 1.01 765 45 46 0 FALSE 1.02
colorectal cancer KRAS_G12V POLD1 13 12 <40yrs -1.15 -2.54 -0.04 1316.69 1.00 179 13 12 0 TRUE 1.16
colorectal cancer KRAS_G12V POLD1 40 16 40-50yrs -1.01 -2.25 0.08 1370.17 1.00 361 38 14 2 TRUE 1.02
colorectal cancer KRAS_G12V POLD1 77 39 50-65yrs -1.07 -2.33 -0.08 1115.13 1.00 775 75 37 2 TRUE 1.22
colorectal cancer KRAS_G12V POLD1 58 45 >65yrs -1.25 -2.64 -0.20 1200.16 1.00 503 58 45 0 TRUE 1.41
non-small cell lung cancer KRAS_G12V POLD1 58 23 50-65yrs -0.05 -1.56 1.14 846.55 1.00 1080 57 22 1 TRUE 0.03
non-small cell lung cancer KRAS_G12V POLD1 92 32 >65yrs -0.02 -1.45 1.15 935.75 1.00 1840 90 30 2 TRUE 0.01
colorectal cancer KRAS_G12V POLD1 188 112 Age:overall -1.11 -2.35 -0.10 1204.16 1.00 1818 184 108 4 TRUE 1.31
non-small cell lung cancer KRAS_G12V POLD1 150 55 Age:overall -0.03 -1.56 1.20 914.78 1.00 2920 147 52 3 TRUE 0.01
colorectal cancer KRAS_G12V INHBA 77 26 50-65yrs 0.39 -0.60 1.31 913.92 1.00 784 73 22 4 FALSE 0.40
colorectal cancer KRAS_G12V INHBA 58 19 >65yrs 0.31 -0.86 1.25 1028.29 1.00 519 56 17 2 FALSE 0.27
non-small cell lung cancer KRAS_G12V INHBA 58 29 50-65yrs -0.74 -2.64 0.82 1263.23 1.00 1075 56 27 2 FALSE 0.41
non-small cell lung cancer KRAS_G12V INHBA 92 55 >65yrs -1.25 -4.09 0.26 761.36 1.00 1821 92 55 0 FALSE 0.56
colorectal cancer KRAS_G12V INHBA 135 45 Age:overall 0.34 -0.80 1.35 1070.20 1.00 1303 129 39 6 FALSE 0.29
non-small cell lung cancer KRAS_G12V INHBA 150 84 Age:overall -0.97 -3.25 0.59 1067.91 1.00 2896 148 82 2 FALSE 0.48
colorectal cancer KRAS_G12V PREX2 23 21 40-50yrs -1.14 -2.52 -0.08 215.99 1.01 212 22 20 1 FALSE 1.16
colorectal cancer KRAS_G12V PREX2 46 34 50-65yrs -1.12 -2.47 -0.13 203.21 1.01 424 44 32 2 FALSE 1.17
colorectal cancer KRAS_G12V PREX2 30 29 >65yrs -1.17 -2.59 -0.13 177.86 1.01 288 30 29 0 FALSE 1.19
non-small cell lung cancer KRAS_G12V PREX2 34 41 50-65yrs -0.25 -1.53 0.78 1014.88 1.00 592 33 40 1 FALSE 0.17
non-small cell lung cancer KRAS_G12V PREX2 54 63 >65yrs -0.08 -1.11 0.94 1294.97 1.00 1022 50 59 4 FALSE 0.05
colorectal cancer KRAS_G12V PREX2 99 84 Age:overall -1.14 -2.46 -0.13 187.34 1.01 924 96 81 3 FALSE 1.19
non-small cell lung cancer KRAS_G12V PREX2 88 104 Age:overall -0.16 -1.32 0.91 1041.89 1.00 1614 83 99 5 FALSE 0.10
colorectal cancer KRAS_G12V AMER1 13 13 <40yrs 0.24 -0.68 1.00 1467.05 1.00 194 13 13 0 FALSE 0.23
colorectal cancer KRAS_G12V AMER1 42 33 40-50yrs 0.48 -0.24 1.22 1417.76 1.00 383 36 27 6 FALSE 0.73
colorectal cancer KRAS_G12V AMER1 90 53 50-65yrs 0.46 -0.15 1.06 1431.55 1.00 836 81 44 9 FALSE 0.85
colorectal cancer KRAS_G12V AMER1 59 70 >65yrs 0.25 -0.44 0.86 1430.77 1.00 532 53 64 6 FALSE 0.35
non-small cell lung cancer KRAS_G12V AMER1 62 48 50-65yrs 0.44 -0.30 1.14 1138.84 1.00 1213 58 44 4 FALSE 0.63
non-small cell lung cancer KRAS_G12V AMER1 101 93 >65yrs 0.39 -0.32 1.06 1221.53 1.00 1955 95 87 6 FALSE 0.59
uterine cancer KRAS_G12V AMER1 34 33 50-65yrs -0.48 -2.54 0.87 1476.34 1.00 457 33 32 1 FALSE 0.23
uterine cancer KRAS_G12V AMER1 17 18 >65yrs 0.36 -1.42 2.03 1127.05 1.00 447 15 16 2 FALSE 0.17
colorectal cancer KRAS_G12V AMER1 204 169 Age:overall 0.36 -0.28 0.97 1528.94 1.00 1945 183 148 21 FALSE 0.60
non-small cell lung cancer KRAS_G12V AMER1 163 141 Age:overall 0.41 -0.37 1.14 1306.83 1.00 3168 153 131 10 FALSE 0.50
uterine cancer KRAS_G12V AMER1 51 51 Age:overall -0.05 -2.21 1.92 1378.36 1.00 904 48 48 3 FALSE 0.02
colorectal cancer KRAS_G12V HLA-A 73 17 50-65yrs -1.91 -5.13 0.02 967.60 1.00 765 73 17 0 FALSE 0.78
colorectal cancer KRAS_G12V HLA-A 54 20 >65yrs -1.58 -4.55 0.24 790.04 1.00 506 53 19 1 FALSE 0.76
colorectal cancer KRAS_G12V HLA-A 127 37 Age:overall -1.72 -4.74 0.20 680.41 1.00 1271 126 36 1 FALSE 0.78
colorectal cancer KRAS_G12V EPHA7 40 13 40-50yrs -0.57 -1.76 0.33 186.03 1.02 360 40 13 0 FALSE 0.52
colorectal cancer KRAS_G12V EPHA7 77 39 50-65yrs -0.53 -1.63 0.33 203.68 1.02 773 75 37 2 FALSE 0.51
colorectal cancer KRAS_G12V EPHA7 58 30 >65yrs -0.47 -1.58 0.42 278.69 1.02 512 55 27 3 FALSE 0.44
non-small cell lung cancer KRAS_G12V EPHA7 58 48 50-65yrs -0.38 -1.61 0.58 508.22 1.00 1059 57 47 1 FALSE 0.30
non-small cell lung cancer KRAS_G12V EPHA7 92 77 >65yrs -0.24 -1.25 0.63 526.11 1.00 1799 88 73 4 FALSE 0.20
colorectal cancer KRAS_G12V EPHA7 175 82 Age:overall -0.52 -1.66 0.33 203.91 1.02 1645 170 77 5 FALSE 0.50
non-small cell lung cancer KRAS_G12V EPHA7 150 125 Age:overall -0.32 -1.47 0.60 603.10 1.00 2858 145 120 5 FALSE 0.25
colorectal cancer KRAS_G12V NCOA3 77 19 50-65yrs -1.43 -4.62 0.28 1020.34 1.00 788 77 19 0 TRUE 0.57
colorectal cancer KRAS_G12V NCOA3 58 23 >65yrs -0.82 -2.62 0.60 960.39 1.00 516 56 21 2 TRUE 0.48
colorectal cancer KRAS_G12V NCOA3 135 42 Age:overall -1.12 -3.55 0.62 1217.18 1.00 1304 133 40 2 TRUE 0.51
non-small cell lung cancer KRAS_G12V DROSHA 34 17 50-65yrs 0.63 -0.75 1.95 971.88 1.00 609 31 14 3 FALSE 0.46
non-small cell lung cancer KRAS_G12V DROSHA 54 34 >65yrs 0.20 -1.49 1.40 587.30 1.01 1034 53 33 1 FALSE 0.11
non-small cell lung cancer KRAS_G12V DROSHA 88 51 Age:overall 0.40 -1.22 1.75 827.12 1.00 1643 84 47 4 FALSE 0.21
colorectal cancer KRAS_G12V SLX4 42 16 50-65yrs -1.44 -4.25 0.50 867.81 1.00 412 41 15 1 FALSE 0.62
colorectal cancer KRAS_G12V SLX4 26 18 >65yrs -1.76 -5.20 0.34 1103.50 1.00 288 26 18 0 FALSE 0.62
colorectal cancer KRAS_G12V SLX4 68 34 Age:overall -1.59 -4.72 0.57 1092.24 1.00 700 67 33 1 FALSE 0.62
colorectal cancer KRAS_G12V INPPL1 22 12 40-50yrs -0.59 -1.94 0.49 498.61 1.00 202 21 11 1 FALSE 0.46
colorectal cancer KRAS_G12V INPPL1 43 29 50-65yrs -0.55 -1.91 0.55 466.93 1.00 406 40 26 3 FALSE 0.44
colorectal cancer KRAS_G12V INPPL1 26 25 >65yrs -0.67 -2.06 0.44 557.54 1.00 286 26 25 0 FALSE 0.53
colorectal cancer KRAS_G12V INPPL1 91 66 Age:overall -0.60 -1.97 0.47 434.59 1.00 894 87 62 4 FALSE 0.50
colorectal cancer KRAS_G13D SPEN 24 23 <40yrs -0.08 -1.05 0.92 1539.31 1.00 183 20 19 4 FALSE 0.06
colorectal cancer KRAS_G13D SPEN 36 25 40-50yrs -0.46 -1.57 0.47 1453.01 1.00 395 35 24 1 FALSE 0.42
colorectal cancer KRAS_G13D SPEN 62 45 50-65yrs -0.31 -1.27 0.53 1655.08 1.00 873 59 42 3 FALSE 0.30
colorectal cancer KRAS_G13D SPEN 54 62 >65yrs -0.69 -1.77 0.17 1527.85 1.00 552 53 61 1 FALSE 0.77
colorectal cancer KRAS_G13D SPEN 176 155 Age:overall -0.38 -1.30 0.43 1455.31 1.00 2003 167 146 9 FALSE 0.43
colorectal cancer KRAS_G13D KMT2C 26 25 <40yrs 0.32 -0.38 1.11 1467.99 1.00 175 20 19 6 FALSE 0.40
colorectal cancer KRAS_G13D KMT2C 33 39 40-50yrs 0.00 -0.80 0.70 1104.94 1.00 381 31 37 2 FALSE 0.00
colorectal cancer KRAS_G13D KMT2C 62 65 50-65yrs 0.15 -0.57 0.84 1524.69 1.00 833 56 59 6 FALSE 0.17
colorectal cancer KRAS_G13D KMT2C 54 69 >65yrs -0.10 -0.89 0.53 1538.63 1.00 530 51 66 3 FALSE 0.11
colorectal cancer KRAS_G13D KMT2C 175 198 Age:overall 0.09 -0.57 0.71 1562.09 1.00 1919 158 181 17 FALSE 0.11
colorectal cancer KRAS_G13D TP53 25 165 <40yrs -0.38 -0.77 0.02 1529.01 1.00 72 10 150 15 TRUE 1.20
colorectal cancer KRAS_G13D TP53 38 350 40-50yrs -0.44 -0.85 -0.08 1338.56 1.00 135 17 329 21 TRUE 1.72
colorectal cancer KRAS_G13D TP53 72 724 50-65yrs -0.44 -0.78 -0.10 1375.37 1.00 366 31 683 41 TRUE 1.96
colorectal cancer KRAS_G13D TP53 62 480 >65yrs -0.42 -0.77 -0.07 1466.94 1.00 260 29 447 33 TRUE 1.76
colorectal cancer KRAS_G13D TP53 197 1719 Age:overall -0.42 -0.76 -0.10 1475.73 1.00 833 87 1609 110 TRUE 1.92
colorectal cancer KRAS_G13D ATRX 38 31 40-50yrs -0.18 -1.26 0.77 1456.99 1.00 392 35 28 3 TRUE 0.14
colorectal cancer KRAS_G13D ATRX 61 31 50-65yrs -0.43 -1.65 0.53 1484.87 1.00 878 60 30 1 TRUE 0.35
colorectal cancer KRAS_G13D ATRX 55 48 >65yrs -0.33 -1.30 0.54 1351.89 1.00 558 52 45 3 TRUE 0.31
colorectal cancer KRAS_G13D ATRX 154 110 Age:overall -0.31 -1.41 0.62 1385.53 1.00 1828 147 103 7 TRUE 0.27
colorectal cancer KRAS_G13D ATR 25 17 <40yrs 0.45 -0.34 1.25 1344.72 1.00 184 21 13 4 FALSE 0.60
colorectal cancer KRAS_G13D ATR 36 22 40-50yrs 0.27 -0.56 0.97 1152.86 1.00 403 35 21 1 FALSE 0.31
colorectal cancer KRAS_G13D ATR 62 48 50-65yrs 0.37 -0.39 1.01 899.42 1.00 875 57 43 5 FALSE 0.53
colorectal cancer KRAS_G13D ATR 54 27 >65yrs 0.28 -0.63 0.97 1003.51 1.00 573 52 25 2 FALSE 0.32
colorectal cancer KRAS_G13D ATR 177 114 Age:overall 0.34 -0.41 0.98 1049.82 1.00 2035 165 102 12 FALSE 0.48
colorectal cancer KRAS_G13D PDGFRA 27 12 <40yrs 1.58 0.44 2.87 1240.69 1.00 207 20 5 7 TRUE 1.92
colorectal cancer KRAS_G13D PDGFRA 37 14 40-50yrs 0.36 -1.20 1.47 1500.53 1.00 434 36 13 1 TRUE 0.22
colorectal cancer KRAS_G13D PDGFRA 66 22 50-65yrs 0.25 -1.16 1.34 1234.20 1.00 989 65 21 1 TRUE 0.15
colorectal cancer KRAS_G13D PDGFRA 61 12 >65yrs 0.08 -1.92 1.23 1369.26 1.00 648 61 12 0 TRUE 0.04
colorectal cancer KRAS_G13D PDGFRA 191 60 Age:overall 0.57 -0.66 1.57 1393.96 1.00 2278 182 51 9 TRUE 0.48
colorectal cancer KRAS_G13D FBXW7 24 28 <40yrs 0.82 0.39 1.29 1316.85 1.00 192 18 22 6 TRUE 3.58
colorectal cancer KRAS_G13D FBXW7 39 60 40-50yrs 0.80 0.37 1.22 1198.80 1.00 402 30 51 9 TRUE 3.70
colorectal cancer KRAS_G13D FBXW7 69 144 50-65yrs 0.82 0.41 1.21 1284.51 1.00 899 49 124 20 TRUE 4.35
colorectal cancer KRAS_G13D FBXW7 61 107 >65yrs 0.73 0.27 1.14 1094.64 1.00 580 50 96 11 TRUE 2.96
colorectal cancer KRAS_G13D FBXW7 193 339 Age:overall 0.79 0.39 1.17 1107.17 1.00 2073 147 293 46 TRUE 4.08
colorectal cancer KRAS_G13D MAP3K1 36 24 40-50yrs -0.05 -1.49 0.97 427.12 1.01 396 35 23 1 FALSE 0.03
colorectal cancer KRAS_G13D MAP3K1 62 34 50-65yrs 0.38 -0.63 1.41 679.74 1.00 879 56 28 6 FALSE 0.33
colorectal cancer KRAS_G13D MAP3K1 54 25 >65yrs -0.24 -2.26 0.92 432.95 1.01 574 54 25 0 FALSE 0.12
colorectal cancer KRAS_G13D MAP3K1 152 83 Age:overall 0.02 -1.38 1.00 411.40 1.01 1849 145 76 7 FALSE 0.01
colorectal cancer KRAS_G13D NSD1 25 15 <40yrs 1.37 0.23 2.59 1209.21 1.00 186 18 8 7 FALSE 1.56
colorectal cancer KRAS_G13D NSD1 36 16 40-50yrs -0.56 -3.15 0.93 1486.52 1.00 402 36 16 0 FALSE 0.24
colorectal cancer KRAS_G13D NSD1 61 22 50-65yrs 0.16 -1.07 1.29 1353.27 1.00 887 59 20 2 FALSE 0.10
colorectal cancer KRAS_G13D NSD1 54 33 >65yrs -0.86 -3.33 0.52 1388.21 1.00 569 54 33 0 FALSE 0.42
colorectal cancer KRAS_G13D NSD1 176 86 Age:overall 0.04 -1.49 1.25 1581.84 1.00 2044 167 77 9 FALSE 0.02
colorectal cancer KRAS_G13D FLT4 36 24 40-50yrs -0.39 -1.78 0.65 1432.09 1.00 395 35 23 1 TRUE 0.28
colorectal cancer KRAS_G13D FLT4 61 42 50-65yrs 0.33 -0.72 1.29 1229.90 1.00 872 55 36 6 TRUE 0.28
colorectal cancer KRAS_G13D FLT4 54 63 >65yrs -0.58 -1.88 0.38 1283.69 1.00 545 52 61 2 TRUE 0.51
colorectal cancer KRAS_G13D FLT4 151 129 Age:overall -0.21 -1.38 0.82 1419.88 1.00 1812 142 120 9 TRUE 0.15
colorectal cancer KRAS_G13D PTPRD 36 18 40-50yrs -0.51 -1.60 0.43 528.18 1.01 402 36 18 0 FALSE 0.46
colorectal cancer KRAS_G13D PTPRD 61 43 50-65yrs -0.42 -1.41 0.51 564.70 1.01 873 58 40 3 FALSE 0.39
colorectal cancer KRAS_G13D PTPRD 54 32 >65yrs -0.46 -1.52 0.43 585.11 1.01 570 52 30 2 FALSE 0.44
colorectal cancer KRAS_G13D PTPRD 151 93 Age:overall -0.46 -1.50 0.42 522.56 1.01 1845 146 88 5 FALSE 0.43
colorectal cancer KRAS_G13D RET 66 30 50-65yrs -0.01 -1.40 1.03 1064.52 1.00 980 64 28 2 TRUE 0.01
colorectal cancer KRAS_G13D RET 61 20 >65yrs 0.01 -1.33 1.11 760.89 1.00 643 59 18 2 TRUE 0.01
colorectal cancer KRAS_G13D RET 127 50 Age:overall 0.00 -1.35 1.17 1073.44 1.00 1623 123 46 4 TRUE 0.00
colorectal cancer KRAS_G13D KDM5A 36 21 40-50yrs -0.15 -1.91 0.86 1038.11 1.00 401 36 21 0 FALSE 0.07
colorectal cancer KRAS_G13D KDM5A 62 35 50-65yrs 0.51 -0.44 1.59 670.31 1.00 885 55 28 7 FALSE 0.48
colorectal cancer KRAS_G13D KDM5A 54 30 >65yrs -0.10 -1.53 0.85 973.35 1.00 568 53 29 1 FALSE 0.06
colorectal cancer KRAS_G13D KDM5A 152 86 Age:overall 0.08 -1.17 0.99 1097.47 1.00 1854 144 78 8 FALSE 0.05
colorectal cancer KRAS_G13D PIK3C2G 33 21 40-50yrs -0.88 -2.37 0.28 890.08 1.00 386 32 20 1 FALSE 0.67
colorectal cancer KRAS_G13D PIK3C2G 61 32 50-65yrs -0.84 -2.31 0.28 852.41 1.00 855 59 30 2 FALSE 0.65
colorectal cancer KRAS_G13D PIK3C2G 54 28 >65yrs -0.97 -2.56 0.22 858.50 1.00 554 54 28 0 FALSE 0.76
colorectal cancer KRAS_G13D PIK3C2G 148 81 Age:overall -0.89 -2.38 0.27 801.14 1.00 1795 145 78 3 FALSE 0.71
colorectal cancer KRAS_G13D CREBBP 23 18 <40yrs 0.48 -0.40 1.36 1460.45 1.00 184 19 14 4 TRUE 0.56
colorectal cancer KRAS_G13D CREBBP 37 31 40-50yrs 0.34 -0.49 1.11 1541.77 1.00 395 33 27 4 TRUE 0.40
colorectal cancer KRAS_G13D CREBBP 63 58 50-65yrs 0.43 -0.32 1.16 1233.76 1.00 867 56 51 7 TRUE 0.63
colorectal cancer KRAS_G13D CREBBP 54 81 >65yrs -0.14 -0.97 0.57 1348.59 1.00 536 51 78 3 TRUE 0.14
colorectal cancer KRAS_G13D CREBBP 177 188 Age:overall 0.27 -0.44 0.91 1385.85 1.00 1982 159 170 18 TRUE 0.37
colorectal cancer KRAS_G13D AXIN2 36 25 40-50yrs 0.09 -0.66 0.80 494.29 1.01 398 33 22 3 TRUE 0.10
colorectal cancer KRAS_G13D AXIN2 62 45 50-65yrs 0.11 -0.56 0.83 472.30 1.01 872 57 40 5 TRUE 0.13
colorectal cancer KRAS_G13D AXIN2 54 39 >65yrs -0.01 -0.86 0.70 452.26 1.01 562 53 38 1 TRUE 0.01
colorectal cancer KRAS_G13D AXIN2 152 109 Age:overall 0.06 -0.68 0.75 520.91 1.01 1832 143 100 9 TRUE 0.07
colorectal cancer KRAS_G13D DOT1L 23 19 <40yrs 0.54 -0.52 1.56 1428.16 1.00 183 19 15 4 FALSE 0.52
colorectal cancer KRAS_G13D DOT1L 36 12 40-50yrs 0.15 -1.10 1.20 1443.50 1.00 404 35 11 1 FALSE 0.10
colorectal cancer KRAS_G13D DOT1L 61 21 50-65yrs 0.24 -0.86 1.22 1592.91 1.00 891 59 19 2 FALSE 0.19
colorectal cancer KRAS_G13D DOT1L 54 32 >65yrs 0.06 -1.02 0.97 1548.00 1.00 569 52 30 2 FALSE 0.04
colorectal cancer KRAS_G13D DOT1L 174 84 Age:overall 0.26 -0.69 1.10 1508.30 1.00 2047 165 75 9 FALSE 0.24
colorectal cancer KRAS_G13D PTPRS 24 26 <40yrs 0.34 -0.17 0.86 1246.86 1.00 172 19 21 5 FALSE 0.71
colorectal cancer KRAS_G13D PTPRS 33 51 40-50yrs 0.30 -0.22 0.78 1132.24 1.00 368 28 46 5 FALSE 0.63
colorectal cancer KRAS_G13D PTPRS 63 98 50-65yrs 0.30 -0.18 0.77 1042.06 1.00 807 54 89 9 FALSE 0.69
colorectal cancer KRAS_G13D PTPRS 54 79 >65yrs 0.26 -0.28 0.76 1171.52 1.00 518 48 73 6 FALSE 0.50
colorectal cancer KRAS_G13D PTPRS 174 254 Age:overall 0.30 -0.17 0.75 1131.28 1.00 1865 149 229 25 FALSE 0.70
colorectal cancer KRAS_G13D SMARCA4 23 19 <40yrs 0.17 -0.54 0.96 1343.05 1.00 184 19 15 4 FALSE 0.18
colorectal cancer KRAS_G13D SMARCA4 36 24 40-50yrs -0.10 -1.02 0.61 1374.42 1.00 394 36 24 0 FALSE 0.09
colorectal cancer KRAS_G13D SMARCA4 63 65 50-65yrs 0.11 -0.54 0.78 1458.39 1.00 861 57 59 6 FALSE 0.13
colorectal cancer KRAS_G13D SMARCA4 54 61 >65yrs 0.00 -0.75 0.66 1461.88 1.00 551 50 57 4 FALSE 0.00
colorectal cancer KRAS_G13D SMARCA4 176 169 Age:overall 0.04 -0.64 0.65 1355.62 1.00 1990 162 155 14 FALSE 0.05
colorectal cancer KRAS_G13D PTPRT 27 18 <40yrs 0.79 0.09 1.82 895.51 1.00 184 19 10 8 FALSE 1.23
colorectal cancer KRAS_G13D PTPRT 36 39 40-50yrs 0.38 -0.50 0.96 1312.90 1.00 385 34 37 2 FALSE 0.53
colorectal cancer KRAS_G13D PTPRT 61 80 50-65yrs 0.52 -0.04 1.05 1185.12 1.00 839 53 72 8 FALSE 1.16
colorectal cancer KRAS_G13D PTPRT 54 48 >65yrs 0.42 -0.28 0.99 1281.93 1.00 555 50 44 4 FALSE 0.73
colorectal cancer KRAS_G13D PTPRT 178 185 Age:overall 0.53 -0.04 1.10 990.43 1.00 1963 156 163 22 FALSE 1.16
colorectal cancer KRAS_G13D HGF 61 24 50-65yrs -1.47 -4.36 0.42 493.22 1.00 885 60 23 1 FALSE 0.64
colorectal cancer KRAS_G13D HGF 54 15 >65yrs -1.74 -4.85 0.28 615.80 1.00 581 54 15 0 FALSE 0.71
colorectal cancer KRAS_G13D HGF 115 39 Age:overall -1.57 -4.51 0.43 497.33 1.00 1466 114 38 1 FALSE 0.65
colorectal cancer KRAS_G13D BLM 36 14 40-50yrs 0.17 -1.07 1.17 1196.07 1.00 405 35 13 1 TRUE 0.11
colorectal cancer KRAS_G13D BLM 61 21 50-65yrs 0.42 -0.62 1.46 1279.19 1.00 890 57 17 4 TRUE 0.38
colorectal cancer KRAS_G13D BLM 54 26 >65yrs 0.10 -1.10 1.05 1042.38 1.00 573 53 25 1 TRUE 0.07
colorectal cancer KRAS_G13D BLM 151 61 Age:overall 0.23 -0.83 1.17 1209.31 1.00 1868 145 55 6 TRUE 0.18
colorectal cancer KRAS_G13D PIK3CA 25 42 <40yrs 1.04 0.59 1.61 1264.85 1.00 184 13 30 12 TRUE 4.37
colorectal cancer KRAS_G13D PIK3CA 37 90 40-50yrs 0.77 0.24 1.19 1460.73 1.00 375 29 82 8 TRUE 2.72
colorectal cancer KRAS_G13D PIK3CA 73 213 50-65yrs 0.97 0.60 1.38 1285.78 1.00 841 42 182 31 TRUE 6.00
colorectal cancer KRAS_G13D PIK3CA 63 166 >65yrs 0.82 0.36 1.19 1370.11 1.00 534 43 146 20 TRUE 3.87
colorectal cancer KRAS_G13D PIK3CA 198 511 Age:overall 0.90 0.53 1.28 1389.48 1.00 1934 127 440 71 TRUE 5.68
colorectal cancer KRAS_G13D ESR1 24 12 <40yrs 0.78 -0.34 1.98 1493.17 1.00 186 20 8 4 TRUE 0.72
colorectal cancer KRAS_G13D ESR1 61 24 50-65yrs 0.42 -0.66 1.40 1380.33 1.00 885 58 21 3 TRUE 0.38
colorectal cancer KRAS_G13D ESR1 54 28 >65yrs -0.37 -2.43 0.90 1115.82 1.00 570 54 28 0 TRUE 0.18
colorectal cancer KRAS_G13D ESR1 139 64 Age:overall 0.29 -1.10 1.32 1441.58 1.00 1641 132 57 7 TRUE 0.20
colorectal cancer KRAS_G13D ALK 25 14 <40yrs 0.96 0.32 1.57 723.12 1.00 208 21 10 4 TRUE 2.58
colorectal cancer KRAS_G13D ALK 39 25 40-50yrs 0.91 0.30 1.51 848.69 1.00 430 35 21 4 TRUE 2.51
colorectal cancer KRAS_G13D ALK 66 44 50-65yrs 0.87 0.19 1.44 797.56 1.00 970 61 39 5 TRUE 2.39
colorectal cancer KRAS_G13D ALK 61 32 >65yrs 0.92 0.25 1.47 839.14 1.00 636 55 26 6 TRUE 2.55
colorectal cancer KRAS_G13D ALK 191 115 Age:overall 0.92 0.30 1.45 737.96 1.00 2244 172 96 19 TRUE 2.76
colorectal cancer KRAS_G13D RNF43 27 31 <40yrs 1.00 0.17 1.92 1640.20 1.00 176 17 21 10 TRUE 1.56
colorectal cancer KRAS_G13D RNF43 36 26 40-50yrs 0.02 -1.04 0.98 1349.68 1.00 393 34 24 2 TRUE 0.02
colorectal cancer KRAS_G13D RNF43 61 87 50-65yrs -0.17 -1.02 0.58 1467.81 1.00 841 57 83 4 TRUE 0.16
colorectal cancer KRAS_G13D RNF43 56 123 >65yrs -0.26 -1.06 0.40 1440.61 1.00 518 49 116 7 TRUE 0.32
colorectal cancer KRAS_G13D RNF43 180 267 Age:overall 0.14 -0.65 0.87 1559.72 1.00 1928 157 244 23 TRUE 0.14
colorectal cancer KRAS_G13D LATS1 61 26 50-65yrs -0.70 -2.45 0.63 1087.15 1.00 858 60 25 1 FALSE 0.42
colorectal cancer KRAS_G13D LATS1 54 14 >65yrs -0.64 -2.33 0.76 967.72 1.00 566 53 13 1 FALSE 0.38
colorectal cancer KRAS_G13D LATS1 115 40 Age:overall -0.66 -2.51 0.83 1085.61 1.00 1424 113 38 2 FALSE 0.38
colorectal cancer KRAS_G13D LATS2 61 35 50-65yrs -0.18 -1.41 0.87 1268.20 1.00 848 59 33 2 FALSE 0.12
colorectal cancer KRAS_G13D LATS2 54 21 >65yrs -0.15 -1.42 0.92 1355.40 1.00 561 52 19 2 FALSE 0.10
colorectal cancer KRAS_G13D LATS2 115 56 Age:overall -0.16 -1.54 0.98 1169.99 1.00 1409 111 52 4 FALSE 0.10
colorectal cancer KRAS_G13D PTEN 25 16 <40yrs 0.61 -0.07 1.18 1204.07 1.00 201 23 14 2 TRUE 1.22
colorectal cancer KRAS_G13D PTEN 39 45 40-50yrs 0.64 0.01 1.20 1143.35 1.00 418 33 39 6 TRUE 1.54
colorectal cancer KRAS_G13D PTEN 68 65 50-65yrs 0.71 0.15 1.25 1421.94 1.00 964 58 55 10 TRUE 1.96
colorectal cancer KRAS_G13D PTEN 61 59 >65yrs 0.58 -0.04 1.12 988.15 1.00 624 55 53 6 TRUE 1.31
colorectal cancer KRAS_G13D PTEN 193 185 Age:overall 0.64 0.07 1.13 1332.19 1.00 2207 169 161 24 TRUE 1.74
colorectal cancer KRAS_G13D BCOR 23 11 <40yrs 0.52 -0.55 1.69 1380.63 1.00 189 19 7 4 FALSE 0.46
colorectal cancer KRAS_G13D BCOR 36 14 40-50yrs -0.18 -1.64 0.83 1416.72 1.01 401 36 14 0 FALSE 0.11
colorectal cancer KRAS_G13D BCOR 63 40 50-65yrs 0.31 -0.61 1.16 1476.27 1.00 875 58 35 5 FALSE 0.32
colorectal cancer KRAS_G13D BCOR 54 47 >65yrs -0.29 -1.60 0.62 1172.54 1.00 558 53 46 1 FALSE 0.22
colorectal cancer KRAS_G13D BCOR 176 112 Age:overall 0.08 -0.88 0.93 1445.11 1.00 2023 166 102 10 FALSE 0.07
colorectal cancer KRAS_G13D CTNNB1 24 20 <40yrs 0.67 0.00 1.43 1358.54 1.00 199 18 14 6 TRUE 1.22
colorectal cancer KRAS_G13D CTNNB1 37 27 40-50yrs 0.48 -0.22 1.07 1640.66 1.00 424 35 25 2 TRUE 0.82
colorectal cancer KRAS_G13D CTNNB1 66 76 50-65yrs 0.48 -0.09 1.01 1283.67 1.00 942 60 70 6 TRUE 1.02
colorectal cancer KRAS_G13D CTNNB1 61 40 >65yrs 0.51 -0.08 1.10 1359.93 1.00 626 56 35 5 TRUE 1.02
colorectal cancer KRAS_G13D CTNNB1 188 163 Age:overall 0.54 -0.02 1.07 1447.67 1.00 2191 169 144 19 TRUE 1.24
colorectal cancer KRAS_G13D ARID1A 27 40 <40yrs 0.50 -0.20 1.24 1413.10 1.00 174 18 31 9 TRUE 0.79
colorectal cancer KRAS_G13D ARID1A 37 51 40-50yrs 0.00 -0.80 0.69 1614.29 1.00 383 34 48 3 TRUE 0.00
colorectal cancer KRAS_G13D ARID1A 63 114 50-65yrs 0.29 -0.27 0.84 1451.96 1.00 829 52 103 11 TRUE 0.51
colorectal cancer KRAS_G13D ARID1A 55 110 >65yrs -0.15 -0.91 0.43 1322.23 1.00 524 50 105 5 TRUE 0.18
colorectal cancer KRAS_G13D ARID1A 182 315 Age:overall 0.16 -0.41 0.73 1458.23 1.00 1910 154 287 28 TRUE 0.24
colorectal cancer KRAS_G13D PIK3R1 23 11 <40yrs 0.19 -0.58 0.87 1198.96 1.00 186 22 10 1 TRUE 0.22
colorectal cancer KRAS_G13D PIK3R1 37 21 40-50yrs 0.20 -0.56 0.88 1056.06 1.00 397 35 19 2 TRUE 0.24
colorectal cancer KRAS_G13D PIK3R1 61 48 50-65yrs 0.22 -0.51 0.83 1172.20 1.00 870 56 43 5 TRUE 0.29
colorectal cancer KRAS_G13D PIK3R1 54 36 >65yrs 0.19 -0.61 0.82 1209.29 1.00 569 51 33 3 TRUE 0.22
colorectal cancer KRAS_G13D PIK3R1 175 116 Age:overall 0.20 -0.49 0.81 1115.91 1.00 2022 164 105 11 TRUE 0.26
colorectal cancer KRAS_G13D IKZF1 36 13 40-50yrs 0.59 -0.35 1.47 1060.51 1.00 404 33 10 3 TRUE 0.69
colorectal cancer KRAS_G13D IKZF1 61 31 50-65yrs 0.53 -0.35 1.29 1057.99 1.00 882 57 27 4 TRUE 0.69
colorectal cancer KRAS_G13D IKZF1 54 33 >65yrs 0.38 -0.68 1.16 874.10 1.01 567 52 31 2 TRUE 0.37
colorectal cancer KRAS_G13D IKZF1 151 77 Age:overall 0.49 -0.38 1.26 1077.36 1.00 1853 142 68 9 TRUE 0.57
colorectal cancer KRAS_G13D TERT 36 23 40-50yrs 0.05 -1.09 0.83 907.50 1.00 399 36 23 0 TRUE 0.03
colorectal cancer KRAS_G13D TERT 61 39 50-65yrs 0.25 -0.65 1.05 878.97 1.00 873 56 34 5 TRUE 0.25
colorectal cancer KRAS_G13D TERT 54 27 >65yrs 0.18 -0.66 0.96 835.99 1.00 573 51 24 3 TRUE 0.17
colorectal cancer KRAS_G13D TERT 151 89 Age:overall 0.16 -0.70 0.94 956.82 1.00 1845 143 81 8 TRUE 0.15
colorectal cancer KRAS_G13D FAT1 30 24 <40yrs 1.37 0.56 2.32 1427.97 1.00 185 19 13 11 FALSE 2.48
colorectal cancer KRAS_G13D FAT1 37 39 40-50yrs 0.50 -0.33 1.24 1239.99 1.00 393 33 35 4 FALSE 0.68
colorectal cancer KRAS_G13D FAT1 65 81 50-65yrs 0.80 0.23 1.42 1564.77 1.00 860 54 70 11 FALSE 2.00
colorectal cancer KRAS_G13D FAT1 55 83 >65yrs 0.04 -0.92 0.78 1379.97 1.00 538 51 79 4 FALSE 0.03
colorectal cancer KRAS_G13D FAT1 187 227 Age:overall 0.68 0.00 1.35 1421.83 1.00 1976 157 197 30 FALSE 1.31
colorectal cancer KRAS_G13D FGFR4 61 17 50-65yrs 0.57 -0.86 1.80 1322.53 1.00 893 58 14 3 TRUE 0.41
colorectal cancer KRAS_G13D FGFR4 54 21 >65yrs -0.04 -1.88 1.23 689.30 1.00 579 53 20 1 TRUE 0.02
colorectal cancer KRAS_G13D FGFR4 115 38 Age:overall 0.24 -1.55 1.77 1204.23 1.00 1472 111 34 4 TRUE 0.11
colorectal cancer KRAS_G13D CIC 23 15 <40yrs -0.30 -1.26 0.64 1433.83 1.00 184 21 13 2 TRUE 0.26
colorectal cancer KRAS_G13D CIC 36 25 40-50yrs -0.45 -1.46 0.44 1577.97 1.00 397 35 24 1 TRUE 0.46
colorectal cancer KRAS_G13D CIC 61 39 50-65yrs -0.49 -1.54 0.36 1568.19 1.00 874 60 38 1 TRUE 0.50
colorectal cancer KRAS_G13D CIC 55 58 >65yrs -0.33 -1.19 0.48 1428.97 1.00 554 51 54 4 TRUE 0.35
colorectal cancer KRAS_G13D CIC 175 137 Age:overall -0.39 -1.28 0.40 1421.18 1.00 2009 167 129 8 TRUE 0.44
colorectal cancer KRAS_G13D KDM6A 36 11 40-50yrs -1.04 -2.94 0.29 292.69 1.01 405 35 10 1 FALSE 0.69
colorectal cancer KRAS_G13D KDM6A 61 26 50-65yrs -1.06 -2.97 0.25 245.44 1.01 882 60 25 1 FALSE 0.71
colorectal cancer KRAS_G13D KDM6A 54 20 >65yrs -1.11 -3.02 0.24 273.20 1.01 577 54 20 0 FALSE 0.75
colorectal cancer KRAS_G13D KDM6A 151 57 Age:overall -1.07 -3.00 0.30 268.79 1.01 1864 149 55 2 FALSE 0.72
colorectal cancer KRAS_G13D NCOR1 23 12 <40yrs 0.26 -0.58 0.95 882.48 1.00 187 22 11 1 FALSE 0.29
colorectal cancer KRAS_G13D NCOR1 36 22 40-50yrs 0.22 -0.63 0.86 946.21 1.00 398 35 21 1 FALSE 0.24
colorectal cancer KRAS_G13D NCOR1 63 56 50-65yrs 0.49 -0.21 1.22 788.47 1.00 868 53 46 10 FALSE 0.77
colorectal cancer KRAS_G13D NCOR1 54 45 >65yrs 0.18 -0.75 0.81 728.92 1.00 560 52 43 2 FALSE 0.19
colorectal cancer KRAS_G13D NCOR1 176 135 Age:overall 0.28 -0.44 0.90 887.04 1.00 2013 162 121 14 FALSE 0.39
colorectal cancer KRAS_G13D POLE 26 22 <40yrs 0.66 -0.13 1.53 1402.70 1.00 182 20 16 6 TRUE 0.96
colorectal cancer KRAS_G13D POLE 36 23 40-50yrs 0.08 -1.26 0.95 657.08 1.00 396 36 23 0 TRUE 0.05
colorectal cancer KRAS_G13D POLE 62 51 50-65yrs 0.62 -0.06 1.38 1429.32 1.00 872 54 43 8 TRUE 1.07
colorectal cancer KRAS_G13D POLE 54 45 >65yrs 0.12 -1.03 0.94 537.01 1.00 559 52 43 2 TRUE 0.09
colorectal cancer KRAS_G13D POLE 178 141 Age:overall 0.36 -0.45 1.10 981.55 1.00 2009 162 125 16 TRUE 0.44
colorectal cancer KRAS_G13D ABL1 37 14 40-50yrs 0.30 -0.68 1.16 965.02 1.00 438 36 13 1 TRUE 0.28
colorectal cancer KRAS_G13D ABL1 68 29 50-65yrs 0.44 -0.46 1.30 1094.76 1.00 986 63 24 5 TRUE 0.48
colorectal cancer KRAS_G13D ABL1 61 24 >65yrs 0.24 -0.88 1.10 1057.18 1.00 637 60 23 1 TRUE 0.20
colorectal cancer KRAS_G13D ABL1 166 67 Age:overall 0.33 -0.64 1.14 1084.06 1.00 2061 159 60 7 TRUE 0.33
colorectal cancer KRAS_G13D FOXP1 23 12 <40yrs 0.35 -0.70 1.24 1244.42 1.00 185 22 11 1 FALSE 0.34
colorectal cancer KRAS_G13D FOXP1 36 17 40-50yrs 0.38 -0.63 1.26 1315.20 1.00 401 34 15 2 FALSE 0.38
colorectal cancer KRAS_G13D FOXP1 62 27 50-65yrs 0.45 -0.40 1.25 1290.14 1.00 884 58 23 4 FALSE 0.53
colorectal cancer KRAS_G13D FOXP1 54 14 >65yrs 0.30 -0.73 1.17 1224.17 1.00 582 53 13 1 FALSE 0.28
colorectal cancer KRAS_G13D FOXP1 175 70 Age:overall 0.36 -0.52 1.13 1293.88 1.00 2052 167 62 8 FALSE 0.40
colorectal cancer KRAS_G13D NOTCH2 61 24 50-65yrs 0.30 -0.87 1.46 1388.54 1.00 858 58 21 3 TRUE 0.22
colorectal cancer KRAS_G13D NOTCH2 54 31 >65yrs -0.06 -1.49 1.00 1548.52 1.00 556 52 29 2 TRUE 0.04
colorectal cancer KRAS_G13D NOTCH2 115 55 Age:overall 0.12 -1.29 1.42 1621.74 1.00 1414 110 50 5 TRUE 0.06
colorectal cancer KRAS_G13D TGFBR2 36 18 40-50yrs 0.59 -0.39 1.51 1456.77 1.00 400 33 15 3 TRUE 0.65
colorectal cancer KRAS_G13D TGFBR2 61 42 50-65yrs 0.86 0.05 1.70 1276.93 1.00 875 53 34 8 TRUE 1.38
colorectal cancer KRAS_G13D TGFBR2 54 46 >65yrs 0.15 -1.11 1.00 1063.38 1.00 553 52 44 2 TRUE 0.11
colorectal cancer KRAS_G13D TGFBR2 151 106 Age:overall 0.53 -0.46 1.38 1453.57 1.00 1828 138 93 13 TRUE 0.60
colorectal cancer KRAS_G13D SMO 37 14 40-50yrs -0.11 -1.22 0.83 724.43 1.01 435 37 14 0 TRUE 0.08
colorectal cancer KRAS_G13D SMO 67 29 50-65yrs -0.02 -1.05 0.89 752.52 1.00 984 64 26 3 TRUE 0.02
colorectal cancer KRAS_G13D SMO 61 21 >65yrs -0.04 -1.07 0.92 661.08 1.00 642 59 19 2 TRUE 0.03
colorectal cancer KRAS_G13D SMO 165 64 Age:overall -0.06 -1.08 0.84 711.05 1.00 2061 160 59 5 TRUE 0.04
colorectal cancer KRAS_G13D RPS6KA4 62 28 50-65yrs 1.03 -0.04 2.07 709.05 1.00 856 56 22 6 FALSE 1.26
colorectal cancer KRAS_G13D RPS6KA4 54 16 >65yrs -0.66 -5.15 1.25 955.75 1.00 564 54 16 0 FALSE 0.16
colorectal cancer KRAS_G13D RPS6KA4 116 44 Age:overall 0.27 -2.31 2.19 1507.11 1.00 1420 110 38 6 FALSE 0.09
colorectal cancer KRAS_G13D KMT2A 26 22 <40yrs 0.67 -0.14 1.56 1378.99 1.00 182 19 15 7 FALSE 0.90
colorectal cancer KRAS_G13D KMT2A 37 22 40-50yrs 0.23 -0.61 1.03 1408.72 1.00 400 35 20 2 FALSE 0.24
colorectal cancer KRAS_G13D KMT2A 62 53 50-65yrs 0.23 -0.54 0.94 1522.59 1.00 867 58 49 4 FALSE 0.27
colorectal cancer KRAS_G13D KMT2A 54 51 >65yrs 0.01 -0.93 0.74 1345.54 1.00 557 52 49 2 FALSE 0.01
colorectal cancer KRAS_G13D KMT2A 179 148 Age:overall 0.28 -0.42 0.95 1483.34 1.00 2006 164 133 15 FALSE 0.39
colorectal cancer KRAS_G13D JAK3 66 28 50-65yrs -1.56 -4.33 0.42 341.00 1.01 982 65 27 1 TRUE 0.72
colorectal cancer KRAS_G13D JAK3 61 22 >65yrs -1.86 -5.02 0.22 334.38 1.01 641 61 22 0 TRUE 0.76
colorectal cancer KRAS_G13D JAK3 127 50 Age:overall -1.71 -4.63 0.38 368.90 1.01 1623 126 49 1 TRUE 0.75
colorectal cancer KRAS_G13D BRCA2 30 26 <40yrs 1.62 0.63 2.64 1467.95 1.00 187 18 14 12 TRUE 2.83
colorectal cancer KRAS_G13D BRCA2 36 38 40-50yrs -0.90 -3.21 0.40 1572.69 1.00 392 36 38 0 TRUE 0.49
colorectal cancer KRAS_G13D BRCA2 63 61 50-65yrs 0.37 -0.48 1.12 1456.53 1.00 871 57 55 6 TRUE 0.44
colorectal cancer KRAS_G13D BRCA2 54 65 >65yrs -0.63 -1.98 0.43 1486.49 1.00 544 52 63 2 TRUE 0.53
colorectal cancer KRAS_G13D BRCA2 183 190 Age:overall 0.12 -1.13 1.14 1619.52 1.00 1994 163 170 20 TRUE 0.08
colorectal cancer KRAS_G13D NOTCH3 23 22 <40yrs 0.48 -0.21 1.26 1200.25 1.00 183 18 17 5 TRUE 0.69
colorectal cancer KRAS_G13D NOTCH3 36 28 40-50yrs 0.37 -0.38 1.09 1412.27 1.00 394 32 24 4 TRUE 0.51
colorectal cancer KRAS_G13D NOTCH3 62 71 50-65yrs 0.29 -0.32 0.93 1400.53 1.00 856 56 65 6 TRUE 0.47
colorectal cancer KRAS_G13D NOTCH3 54 79 >65yrs 0.15 -0.51 0.74 1368.33 1.00 538 49 74 5 TRUE 0.20
colorectal cancer KRAS_G13D NOTCH3 175 200 Age:overall 0.33 -0.27 0.92 1313.54 1.00 1971 155 180 20 TRUE 0.58
colorectal cancer KRAS_G13D NOTCH4 25 12 <40yrs 0.32 -0.47 1.20 1074.06 1.00 180 21 8 4 TRUE 0.34
colorectal cancer KRAS_G13D NOTCH4 33 19 40-50yrs 0.08 -0.81 0.84 1363.81 1.00 387 32 18 1 TRUE 0.07
colorectal cancer KRAS_G13D NOTCH4 62 43 50-65yrs 0.12 -0.68 0.83 1502.90 1.00 840 59 40 3 TRUE 0.12
colorectal cancer KRAS_G13D NOTCH4 54 48 >65yrs 0.07 -0.71 0.76 1322.70 1.00 542 51 45 3 TRUE 0.07
colorectal cancer KRAS_G13D NOTCH4 174 122 Age:overall 0.16 -0.58 0.85 1379.69 1.00 1949 163 111 11 TRUE 0.18
colorectal cancer KRAS_G13D FGFR3 66 25 50-65yrs -0.62 -2.55 0.88 1150.41 1.00 987 64 23 2 TRUE 0.31
colorectal cancer KRAS_G13D FGFR3 61 24 >65yrs -1.38 -4.97 0.37 1229.47 1.00 638 61 24 0 TRUE 0.53
colorectal cancer KRAS_G13D FGFR3 127 49 Age:overall -1.00 -3.51 0.72 1295.26 1.00 1625 125 47 2 TRUE 0.44
colorectal cancer KRAS_G13D IGF1R 23 11 <40yrs -0.50 -1.87 0.62 1427.12 1.00 186 23 11 0 TRUE 0.37
colorectal cancer KRAS_G13D IGF1R 36 11 40-50yrs -0.51 -1.85 0.59 1417.37 1.00 404 36 11 0 TRUE 0.38
colorectal cancer KRAS_G13D IGF1R 61 25 50-65yrs -0.22 -1.43 0.85 1374.38 1.00 887 58 22 3 TRUE 0.16
colorectal cancer KRAS_G13D IGF1R 54 33 >65yrs -0.40 -1.58 0.60 1547.73 1.00 568 52 31 2 TRUE 0.33
colorectal cancer KRAS_G13D IGF1R 174 80 Age:overall -0.40 -1.56 0.55 1283.07 1.00 2045 169 75 5 TRUE 0.33
colorectal cancer KRAS_G13D KDM5C 61 24 50-65yrs 0.22 -1.16 1.45 1284.02 1.00 888 58 21 3 FALSE 0.13
colorectal cancer KRAS_G13D KDM5C 54 26 >65yrs -0.31 -1.98 0.85 943.17 1.00 574 53 25 1 FALSE 0.17
colorectal cancer KRAS_G13D KDM5C 115 50 Age:overall -0.05 -1.81 1.40 1287.54 1.00 1462 111 46 4 FALSE 0.02
colorectal cancer KRAS_G13D EPHB1 23 13 <40yrs -0.36 -1.88 1.27 1284.77 1.00 185 20 10 3 FALSE 0.18
colorectal cancer KRAS_G13D EPHB1 61 31 50-65yrs -1.22 -3.90 0.27 1156.43 1.00 876 61 31 0 FALSE 0.62
colorectal cancer KRAS_G13D EPHB1 54 28 >65yrs -1.26 -3.79 0.18 1046.86 1.00 569 54 28 0 FALSE 0.66
colorectal cancer KRAS_G13D EPHB1 138 72 Age:overall -0.94 -3.04 0.56 1163.05 1.00 1630 135 69 3 FALSE 0.54
colorectal cancer KRAS_G13D IRS2 23 13 <40yrs 0.17 -0.74 0.98 1329.77 1.00 184 21 11 2 FALSE 0.15
colorectal cancer KRAS_G13D IRS2 36 19 40-50yrs 0.20 -0.70 1.00 1255.78 1.00 400 33 16 3 FALSE 0.19
colorectal cancer KRAS_G13D IRS2 61 30 50-65yrs 0.11 -0.77 0.88 999.39 1.00 882 59 28 2 FALSE 0.10
colorectal cancer KRAS_G13D IRS2 54 25 >65yrs 0.08 -0.90 0.84 1075.46 1.00 574 53 24 1 FALSE 0.07
colorectal cancer KRAS_G13D IRS2 174 87 Age:overall 0.14 -0.68 0.87 951.80 1.00 2040 166 79 8 FALSE 0.14
colorectal cancer KRAS_G13D FANCA 23 11 <40yrs 1.34 0.34 2.52 1358.26 1.00 189 17 5 6 TRUE 1.79
colorectal cancer KRAS_G13D FANCA 36 11 40-50yrs 0.76 -0.33 1.71 1465.18 1.00 405 35 10 1 TRUE 0.86
colorectal cancer KRAS_G13D FANCA 61 31 50-65yrs 0.86 -0.03 1.69 1194.50 1.00 885 57 27 4 TRUE 1.36
colorectal cancer KRAS_G13D FANCA 54 12 >65yrs 0.58 -0.79 1.51 1091.56 1.00 583 54 12 0 TRUE 0.49
colorectal cancer KRAS_G13D FANCA 174 65 Age:overall 0.88 -0.01 1.72 1392.98 1.00 2062 163 54 11 TRUE 1.33
colorectal cancer KRAS_G13D PIK3CB 33 21 40-50yrs -1.93 -4.69 -0.06 1075.00 1.00 388 32 20 1 FALSE 0.98
colorectal cancer KRAS_G13D PIK3CB 61 17 50-65yrs -2.10 -5.16 -0.16 1059.30 1.00 866 61 17 0 FALSE 1.04
colorectal cancer KRAS_G13D PIK3CB 54 22 >65yrs -2.15 -5.15 -0.26 957.01 1.00 560 54 22 0 FALSE 1.10
colorectal cancer KRAS_G13D PIK3CB 148 60 Age:overall -2.06 -5.04 -0.17 1046.25 1.00 1814 147 59 1 FALSE 1.08
colorectal cancer KRAS_G13D ERBB3 24 13 <40yrs 0.59 -0.20 1.38 1276.96 1.00 185 21 10 3 TRUE 0.83
colorectal cancer KRAS_G13D ERBB3 36 14 40-50yrs 0.49 -0.32 1.31 1446.52 1.00 404 34 12 2 TRUE 0.65
colorectal cancer KRAS_G13D ERBB3 62 48 50-65yrs 0.62 -0.06 1.33 785.19 1.00 868 55 41 7 TRUE 1.08
colorectal cancer KRAS_G13D ERBB3 54 47 >65yrs 0.34 -0.44 1.04 1301.83 1.00 558 51 44 3 TRUE 0.43
colorectal cancer KRAS_G13D ERBB3 176 122 Age:overall 0.51 -0.12 1.15 1440.81 1.00 2015 161 107 15 TRUE 0.87
colorectal cancer KRAS_G13D SMAD4 24 33 <40yrs -0.22 -0.75 0.30 1154.04 1.00 187 19 28 5 TRUE 0.39
colorectal cancer KRAS_G13D SMAD4 37 68 40-50yrs -0.31 -0.85 0.16 1284.22 1.00 390 35 66 2 TRUE 0.63
colorectal cancer KRAS_G13D SMAD4 67 151 50-65yrs -0.30 -0.80 0.18 1299.80 1.00 870 61 145 6 TRUE 0.67
colorectal cancer KRAS_G13D SMAD4 62 108 >65yrs -0.24 -0.72 0.24 1030.63 1.00 573 53 99 9 TRUE 0.48
colorectal cancer KRAS_G13D SMAD4 190 360 Age:overall -0.27 -0.76 0.20 1324.57 1.00 2020 168 338 22 TRUE 0.57
colorectal cancer KRAS_G13D ATM 30 24 <40yrs 1.39 0.42 2.40 1448.44 1.00 202 19 13 11 TRUE 2.18
colorectal cancer KRAS_G13D ATM 37 33 40-50yrs 0.29 -0.63 1.15 1323.76 1.00 426 34 30 3 TRUE 0.28
colorectal cancer KRAS_G13D ATM 66 87 50-65yrs 0.24 -0.48 0.91 1409.04 1.00 945 60 81 6 TRUE 0.31
colorectal cancer KRAS_G13D ATM 62 87 >65yrs -0.21 -1.12 0.57 1454.99 1.00 595 58 83 4 TRUE 0.20
colorectal cancer KRAS_G13D ATM 195 231 Age:overall 0.43 -0.39 1.19 1482.82 1.00 2168 171 207 24 TRUE 0.56
colorectal cancer KRAS_G13D RB1 37 15 40-50yrs -0.68 -2.34 0.59 806.61 1.00 435 37 15 0 TRUE 0.44
colorectal cancer KRAS_G13D RB1 67 20 50-65yrs -0.49 -1.90 0.72 647.92 1.01 994 65 18 2 TRUE 0.31
colorectal cancer KRAS_G13D RB1 61 24 >65yrs -0.60 -2.03 0.64 719.38 1.00 641 60 23 1 TRUE 0.41
colorectal cancer KRAS_G13D RB1 165 59 Age:overall -0.58 -2.01 0.63 623.45 1.00 2070 162 56 3 TRUE 0.40
colorectal cancer KRAS_G13D KMT2D 24 41 <40yrs 0.33 -0.50 1.09 1533.32 1.00 173 18 35 6 FALSE 0.40
colorectal cancer KRAS_G13D KMT2D 39 52 40-50yrs 0.36 -0.39 1.12 1546.96 1.00 384 32 45 7 FALSE 0.48
colorectal cancer KRAS_G13D KMT2D 66 122 50-65yrs 0.40 -0.19 1.02 1349.57 1.00 832 53 109 13 FALSE 0.73
colorectal cancer KRAS_G13D KMT2D 56 173 >65yrs -0.37 -1.08 0.25 1458.88 1.00 507 49 166 7 FALSE 0.54
colorectal cancer KRAS_G13D KMT2D 185 388 Age:overall 0.18 -0.48 0.81 1409.62 1.00 1896 152 355 33 FALSE 0.23
colorectal cancer KRAS_G13D TSC2 23 14 <40yrs 0.31 -0.72 1.35 1470.94 1.00 186 19 10 4 TRUE 0.26
colorectal cancer KRAS_G13D TSC2 36 19 40-50yrs 0.02 -0.97 0.93 1518.82 1.00 399 34 17 2 TRUE 0.01
colorectal cancer KRAS_G13D TSC2 62 36 50-65yrs 0.01 -0.87 0.80 1378.08 1.00 878 59 33 3 TRUE 0.01
colorectal cancer KRAS_G13D TSC2 54 46 >65yrs -0.40 -1.63 0.53 1381.35 1.00 560 54 46 0 TRUE 0.31
colorectal cancer KRAS_G13D TSC2 175 115 Age:overall -0.01 -0.89 0.77 1438.83 1.00 2023 166 106 9 TRUE 0.01
colorectal cancer KRAS_G13D APC 48 246 <40yrs 0.66 0.23 1.11 1617.59 1.00 81 8 206 40 TRUE 2.48
colorectal cancer KRAS_G13D APC 50 494 40-50yrs 0.42 -0.01 0.84 1211.27 1.00 159 10 454 40 TRUE 1.33
colorectal cancer KRAS_G13D APC 100 1094 50-65yrs 0.41 0.03 0.81 1376.20 1.00 352 18 1012 82 TRUE 1.51
colorectal cancer KRAS_G13D APC 85 704 >65yrs 0.48 0.10 0.88 1547.80 1.00 246 17 636 68 TRUE 1.85
colorectal cancer KRAS_G13D APC 283 2538 Age:overall 0.50 0.13 0.88 1073.98 1.00 838 53 2308 230 TRUE 2.00
colorectal cancer KRAS_G13D ERBB2 24 13 <40yrs 0.72 -0.05 1.44 1377.19 1.00 201 22 11 2 TRUE 1.23
colorectal cancer KRAS_G13D ERBB2 37 13 40-50yrs 0.66 -0.14 1.31 1442.48 1.00 436 36 12 1 TRUE 1.14
colorectal cancer KRAS_G13D ERBB2 67 49 50-65yrs 0.76 0.10 1.36 1242.71 1.00 971 60 42 7 TRUE 1.63
colorectal cancer KRAS_G13D ERBB2 61 29 >65yrs 0.73 0.02 1.37 1199.24 1.00 638 56 24 5 TRUE 1.47
colorectal cancer KRAS_G13D ERBB2 189 104 Age:overall 0.72 0.05 1.33 1190.35 1.00 2246 174 89 15 TRUE 1.52
colorectal cancer KRAS_G13D JAK1 28 16 <40yrs 1.59 0.65 2.56 1552.70 1.00 188 20 8 8 TRUE 2.87
colorectal cancer KRAS_G13D JAK1 36 13 40-50yrs 0.81 -0.30 1.78 1406.73 1.00 406 34 11 2 TRUE 0.92
colorectal cancer KRAS_G13D JAK1 61 20 50-65yrs 0.88 -0.07 1.76 1115.22 1.00 891 58 17 3 TRUE 1.22
colorectal cancer KRAS_G13D JAK1 54 26 >65yrs 0.35 -1.10 1.31 1430.15 1.00 573 53 25 1 TRUE 0.25
colorectal cancer KRAS_G13D JAK1 179 75 Age:overall 0.92 -0.01 1.76 1115.38 1.00 2058 165 61 14 TRUE 1.38
colorectal cancer KRAS_G13D ARID2 36 21 40-50yrs 0.13 -0.85 1.04 1411.99 1.00 399 33 18 3 FALSE 0.10
colorectal cancer KRAS_G13D ARID2 61 36 50-65yrs -0.02 -0.98 0.80 1430.09 1.00 878 59 34 2 FALSE 0.01
colorectal cancer KRAS_G13D ARID2 55 44 >65yrs -0.02 -0.97 0.78 1494.83 1.00 557 52 41 3 FALSE 0.01
colorectal cancer KRAS_G13D ARID2 152 101 Age:overall 0.02 -0.94 0.83 1435.70 1.00 1834 144 93 8 FALSE 0.01
colorectal cancer KRAS_G13D SOX17 33 11 40-50yrs -0.06 -1.36 1.07 1241.87 1.00 393 32 10 1 FALSE 0.04
colorectal cancer KRAS_G13D SOX17 61 32 50-65yrs -0.10 -1.30 0.89 1517.10 1.00 850 59 30 2 FALSE 0.07
colorectal cancer KRAS_G13D SOX17 54 47 >65yrs -0.02 -0.99 0.86 1442.71 1.00 541 50 43 4 FALSE 0.02
colorectal cancer KRAS_G13D SOX17 148 90 Age:overall -0.06 -1.17 0.90 1450.59 1.00 1784 141 83 7 FALSE 0.04
colorectal cancer KRAS_G13D MTOR 23 15 <40yrs 0.57 -0.08 1.26 777.47 1.00 187 19 11 4 TRUE 0.98
colorectal cancer KRAS_G13D MTOR 36 26 40-50yrs 0.46 -0.22 1.15 657.65 1.00 395 34 24 2 TRUE 0.74
colorectal cancer KRAS_G13D MTOR 65 54 50-65yrs 0.57 -0.05 1.21 789.55 1.01 864 56 45 9 TRUE 1.13
colorectal cancer KRAS_G13D MTOR 54 45 >65yrs 0.40 -0.37 1.07 532.10 1.00 558 52 43 2 TRUE 0.60
colorectal cancer KRAS_G13D MTOR 178 140 Age:overall 0.50 -0.14 1.13 594.00 1.00 2004 161 123 17 TRUE 0.97
colorectal cancer KRAS_G13D IRS1 33 17 40-50yrs 0.36 -0.83 1.15 186.66 1.03 390 32 16 1 FALSE 0.33
colorectal cancer KRAS_G13D IRS1 64 34 50-65yrs 0.63 -0.27 1.47 726.50 1.00 854 57 27 7 FALSE 0.84
colorectal cancer KRAS_G13D IRS1 54 36 >65yrs 0.29 -0.82 1.04 89.34 1.04 548 52 34 2 FALSE 0.25
colorectal cancer KRAS_G13D IRS1 151 87 Age:overall 0.42 -0.57 1.22 387.88 1.02 1792 141 77 10 FALSE 0.44
colorectal cancer KRAS_G13D NOTCH1 28 18 <40yrs 0.88 -0.05 1.88 1521.08 1.00 202 21 11 7 TRUE 1.14
colorectal cancer KRAS_G13D NOTCH1 37 27 40-50yrs 0.07 -1.04 0.92 1394.63 1.00 429 36 26 1 TRUE 0.05
colorectal cancer KRAS_G13D NOTCH1 68 55 50-65yrs 0.43 -0.30 1.17 1557.31 1.00 968 62 49 6 TRUE 0.62
colorectal cancer KRAS_G13D NOTCH1 62 72 >65yrs 0.01 -0.87 0.72 1491.72 1.00 609 58 68 4 TRUE 0.01
colorectal cancer KRAS_G13D NOTCH1 195 172 Age:overall 0.35 -0.40 1.07 1389.36 1.00 2208 177 154 18 TRUE 0.46
colorectal cancer KRAS_G13D NTRK1 24 12 <40yrs 0.75 -0.36 1.77 1273.15 1.00 186 21 9 3 TRUE 0.78
colorectal cancer KRAS_G13D NTRK1 61 19 50-65yrs 0.52 -0.68 1.50 1427.88 1.00 889 59 17 2 TRUE 0.48
colorectal cancer KRAS_G13D NTRK1 54 26 >65yrs 0.53 -0.47 1.39 1373.75 1.00 574 51 23 3 TRUE 0.56
colorectal cancer KRAS_G13D NTRK1 139 57 Age:overall 0.61 -0.40 1.57 1463.57 1.00 1649 131 49 8 TRUE 0.65
colorectal cancer KRAS_G13D CASP8 33 11 40-50yrs 0.85 -0.34 1.90 1447.44 1.00 395 31 9 2 FALSE 0.89
colorectal cancer KRAS_G13D CASP8 64 30 50-65yrs 1.31 0.46 2.15 1326.05 1.00 858 56 22 8 FALSE 2.57
colorectal cancer KRAS_G13D CASP8 55 46 >65yrs 0.40 -0.55 1.23 1530.95 1.00 543 51 42 4 FALSE 0.42
colorectal cancer KRAS_G13D CASP8 152 87 Age:overall 0.85 -0.14 1.84 1441.62 1.00 1796 138 73 14 FALSE 1.01
colorectal cancer KRAS_G13D SETD2 27 20 <40yrs 1.40 0.46 2.35 1408.59 1.00 184 18 11 9 FALSE 2.30
colorectal cancer KRAS_G13D SETD2 36 15 40-50yrs 0.07 -1.66 1.15 1577.46 1.00 402 36 15 0 FALSE 0.03
colorectal cancer KRAS_G13D SETD2 62 49 50-65yrs 0.65 -0.22 1.37 1475.50 1.00 872 56 43 6 FALSE 0.98
colorectal cancer KRAS_G13D SETD2 54 29 >65yrs 0.05 -1.49 1.01 1525.86 1.00 571 53 28 1 FALSE 0.03
colorectal cancer KRAS_G13D SETD2 179 113 Age:overall 0.56 -0.55 1.45 1655.46 1.00 2029 163 97 16 FALSE 0.59
colorectal cancer KRAS_G13D PBRM1 36 21 40-50yrs -0.09 -1.15 0.83 1416.43 1.00 398 34 19 2 TRUE 0.07
colorectal cancer KRAS_G13D PBRM1 63 32 50-65yrs -0.03 -0.98 0.86 1433.90 1.00 882 59 28 4 TRUE 0.02
colorectal cancer KRAS_G13D PBRM1 54 31 >65yrs -0.28 -1.67 0.60 1099.18 1.00 566 54 31 0 TRUE 0.20
colorectal cancer KRAS_G13D PBRM1 153 84 Age:overall -0.14 -1.18 0.73 1477.55 1.00 1846 147 78 6 TRUE 0.11
colorectal cancer KRAS_G13D EPHA3 25 14 <40yrs 1.14 0.15 2.28 1319.05 1.00 188 18 7 7 FALSE 1.44
colorectal cancer KRAS_G13D EPHA3 36 15 40-50yrs 0.49 -0.53 1.40 1340.17 1.00 404 34 13 2 FALSE 0.50
colorectal cancer KRAS_G13D EPHA3 61 39 50-65yrs 0.26 -0.78 1.06 1605.79 1.00 870 59 37 2 FALSE 0.23
colorectal cancer KRAS_G13D EPHA3 54 45 >65yrs 0.25 -0.70 1.02 1606.21 1.00 558 51 42 3 FALSE 0.24
colorectal cancer KRAS_G13D EPHA3 176 113 Age:overall 0.53 -0.27 1.31 1542.15 1.00 2020 162 99 14 FALSE 0.73
colorectal cancer KRAS_G13D KIT 37 13 40-50yrs -5.19 -11.19 -1.30 360.54 1.00 436 37 13 0 TRUE 1.31
colorectal cancer KRAS_G13D KIT 66 20 50-65yrs -5.20 -11.35 -1.29 358.36 1.00 990 66 20 0 TRUE 1.31
colorectal cancer KRAS_G13D KIT 61 17 >65yrs -5.20 -11.40 -1.21 363.74 1.00 644 61 17 0 TRUE 1.30
colorectal cancer KRAS_G13D KIT 164 50 Age:overall -5.20 -11.22 -1.28 366.62 1.00 2070 164 50 0 TRUE 1.32
colorectal cancer KRAS_G13D KDR 27 11 <40yrs 1.23 0.28 2.29 1362.73 1.00 206 22 6 5 TRUE 1.75
colorectal cancer KRAS_G13D KDR 66 29 50-65yrs 0.53 -0.77 1.40 1318.79 1.00 982 65 28 1 TRUE 0.47
colorectal cancer KRAS_G13D KDR 63 26 >65yrs 0.91 0.08 1.68 1331.34 1.00 643 58 21 5 TRUE 1.60
colorectal cancer KRAS_G13D KDR 156 66 Age:overall 0.87 -0.09 1.78 1476.91 1.00 1831 145 55 11 TRUE 1.20
colorectal cancer KRAS_G13D RICTOR 36 13 40-50yrs 0.74 -0.20 1.52 1407.01 1.00 407 34 11 2 FALSE 1.07
colorectal cancer KRAS_G13D RICTOR 61 24 50-65yrs 0.73 -0.14 1.50 1243.38 1.00 887 58 21 3 FALSE 1.10
colorectal cancer KRAS_G13D RICTOR 55 25 >65yrs 0.76 -0.09 1.46 1316.52 1.00 577 51 21 4 FALSE 1.24
colorectal cancer KRAS_G13D RICTOR 152 62 Age:overall 0.75 -0.10 1.47 1226.18 1.00 1871 143 53 9 FALSE 1.24
colorectal cancer KRAS_G13D RAD50 36 13 40-50yrs 0.50 -0.50 1.31 1197.64 1.00 404 35 12 1 FALSE 0.55
colorectal cancer KRAS_G13D RAD50 62 22 50-65yrs 0.61 -0.31 1.46 1269.21 1.00 889 58 18 4 FALSE 0.77
colorectal cancer KRAS_G13D RAD50 55 20 >65yrs 0.52 -0.42 1.31 1369.33 1.00 579 53 18 2 FALSE 0.62
colorectal cancer KRAS_G13D RAD50 153 55 Age:overall 0.55 -0.38 1.33 1163.85 1.00 1872 146 48 7 FALSE 0.67
colorectal cancer KRAS_G13D CSF1R 37 15 40-50yrs -0.05 -1.31 1.07 628.25 1.00 437 36 14 1 TRUE 0.03
colorectal cancer KRAS_G13D CSF1R 66 21 50-65yrs 0.06 -1.18 1.22 612.27 1.00 993 63 18 3 TRUE 0.04
colorectal cancer KRAS_G13D CSF1R 61 15 >65yrs -0.18 -1.62 0.94 685.81 1.00 646 61 15 0 TRUE 0.10
colorectal cancer KRAS_G13D CSF1R 164 51 Age:overall -0.06 -1.28 0.99 590.48 1.00 2076 160 47 4 TRUE 0.04
colorectal cancer KRAS_G13D PTCH1 26 16 <40yrs 0.85 -0.04 1.94 1617.22 1.00 186 20 10 6 TRUE 1.05
colorectal cancer KRAS_G13D PTCH1 36 21 40-50yrs 0.11 -1.06 1.03 1392.64 1.00 397 35 20 1 TRUE 0.08
colorectal cancer KRAS_G13D PTCH1 65 53 50-65yrs 0.64 -0.10 1.39 1551.36 1.00 874 57 45 8 TRUE 1.00
colorectal cancer KRAS_G13D PTCH1 54 55 >65yrs -0.22 -1.61 0.72 1231.83 1.00 550 53 54 1 TRUE 0.15
colorectal cancer KRAS_G13D PTCH1 181 145 Age:overall 0.34 -0.54 1.10 1612.22 1.00 2007 165 129 16 TRUE 0.39
colorectal cancer KRAS_G13D TET1 29 16 <40yrs 1.31 0.34 2.44 1361.39 1.00 180 21 8 8 FALSE 1.85
colorectal cancer KRAS_G13D TET1 33 23 40-50yrs -0.23 -2.22 0.96 1421.11 1.00 389 33 23 0 FALSE 0.11
colorectal cancer KRAS_G13D TET1 61 27 50-65yrs 0.43 -0.62 1.39 1469.03 1.00 858 58 24 3 FALSE 0.40
colorectal cancer KRAS_G13D TET1 54 37 >65yrs -0.02 -1.32 0.93 1471.88 1.00 550 52 35 2 FALSE 0.01
colorectal cancer KRAS_G13D TET1 177 103 Age:overall 0.38 -0.70 1.23 1443.76 1.00 1977 164 90 13 FALSE 0.35
colorectal cancer KRAS_G13D FGFR2 37 14 40-50yrs -0.94 -2.91 0.60 1203.91 1.00 435 37 14 0 TRUE 0.53
colorectal cancer KRAS_G13D FGFR2 66 15 50-65yrs -0.83 -2.75 0.75 1132.16 1.00 994 65 14 1 TRUE 0.46
colorectal cancer KRAS_G13D FGFR2 61 17 >65yrs -0.86 -2.80 0.61 1161.50 1.00 645 60 16 1 TRUE 0.50
colorectal cancer KRAS_G13D FGFR2 164 46 Age:overall -0.88 -2.79 0.56 1211.31 1.00 2074 162 44 2 TRUE 0.50
colorectal cancer KRAS_G13D TBX3 36 13 40-50yrs -0.29 -1.69 0.68 428.50 1.00 404 36 13 0 FALSE 0.19
colorectal cancer KRAS_G13D TBX3 62 30 50-65yrs -0.05 -1.09 1.00 656.79 1.01 882 58 26 4 FALSE 0.03
colorectal cancer KRAS_G13D TBX3 54 30 >65yrs -0.26 -1.51 0.66 423.92 1.00 572 53 29 1 FALSE 0.19
colorectal cancer KRAS_G13D TBX3 152 73 Age:overall -0.20 -1.40 0.70 445.40 1.00 1858 147 68 5 FALSE 0.15
colorectal cancer KRAS_G13D HNF1A 66 25 50-65yrs 0.45 -0.99 1.77 130.29 1.02 989 62 21 4 TRUE 0.28
colorectal cancer KRAS_G13D HNF1A 61 19 >65yrs -0.93 -5.28 0.86 1191.33 1.00 641 61 19 0 TRUE 0.25
colorectal cancer KRAS_G13D HNF1A 127 44 Age:overall -0.22 -2.80 1.59 1382.96 1.00 1630 123 40 4 TRUE 0.07
colorectal cancer KRAS_G13D DICER1 27 11 <40yrs 1.04 0.05 2.28 1477.29 1.00 189 21 5 6 TRUE 1.22
colorectal cancer KRAS_G13D DICER1 36 19 40-50yrs 0.34 -0.82 1.24 1507.32 1.00 400 35 18 1 TRUE 0.28
colorectal cancer KRAS_G13D DICER1 61 23 50-65yrs 0.32 -0.89 1.22 1380.98 1.00 888 60 22 1 TRUE 0.26
colorectal cancer KRAS_G13D DICER1 54 23 >65yrs 0.40 -0.57 1.21 1387.02 1.00 577 52 21 2 TRUE 0.41
colorectal cancer KRAS_G13D DICER1 178 76 Age:overall 0.51 -0.39 1.30 1368.45 1.00 2054 168 66 10 TRUE 0.63
colorectal cancer KRAS_G13D SMAD3 36 33 40-50yrs -0.13 -1.11 0.69 1367.99 1.00 391 34 31 2 TRUE 0.11
colorectal cancer KRAS_G13D SMAD3 61 44 50-65yrs -0.10 -1.00 0.74 1423.20 1.00 871 58 41 3 TRUE 0.08
colorectal cancer KRAS_G13D SMAD3 54 23 >65yrs -0.13 -1.09 0.75 1209.22 1.00 575 52 21 2 TRUE 0.11
colorectal cancer KRAS_G13D SMAD3 151 100 Age:overall -0.11 -1.08 0.71 1404.66 1.00 1837 144 93 7 TRUE 0.10
colorectal cancer KRAS_G13D NTRK3 23 11 <40yrs -0.22 -1.48 1.00 992.47 1.00 187 20 8 3 FALSE 0.14
colorectal cancer KRAS_G13D NTRK3 36 16 40-50yrs -0.53 -2.04 0.58 1270.77 1.00 403 36 16 0 FALSE 0.38
colorectal cancer KRAS_G13D NTRK3 61 21 50-65yrs -0.56 -2.00 0.48 1275.01 1.00 886 61 21 0 FALSE 0.42
colorectal cancer KRAS_G13D NTRK3 54 22 >65yrs -0.47 -1.80 0.55 1387.89 1.00 576 53 21 1 FALSE 0.35
colorectal cancer KRAS_G13D NTRK3 174 70 Age:overall -0.44 -1.64 0.55 1190.10 1.00 2052 170 66 4 FALSE 0.36
colorectal cancer KRAS_G13D AXIN1 61 22 50-65yrs 0.37 -1.04 1.51 1545.51 1.00 890 58 19 3 FALSE 0.25
colorectal cancer KRAS_G13D AXIN1 54 37 >65yrs -0.27 -1.77 0.82 1473.60 1.00 565 52 35 2 FALSE 0.16
colorectal cancer KRAS_G13D AXIN1 115 59 Age:overall 0.05 -1.63 1.66 1502.35 1.00 1455 110 54 5 FALSE 0.02
colorectal cancer KRAS_G13D GRIN2A 24 15 <40yrs 0.00 -0.83 0.75 789.34 1.00 183 21 12 3 FALSE 0.00
colorectal cancer KRAS_G13D GRIN2A 36 29 40-50yrs -0.09 -0.95 0.65 701.83 1.01 394 34 27 2 FALSE 0.08
colorectal cancer KRAS_G13D GRIN2A 61 50 50-65yrs -0.01 -0.78 0.71 770.71 1.01 862 56 45 5 FALSE 0.01
colorectal cancer KRAS_G13D GRIN2A 54 42 >65yrs -0.21 -1.16 0.48 360.46 1.02 558 54 42 0 FALSE 0.20
colorectal cancer KRAS_G13D GRIN2A 175 136 Age:overall -0.08 -0.84 0.57 608.76 1.01 1997 165 126 10 FALSE 0.08
colorectal cancer KRAS_G13D PALB2 25 13 <40yrs 1.28 0.21 2.35 1531.88 1.00 186 20 8 5 TRUE 1.77
colorectal cancer KRAS_G13D PALB2 61 18 50-65yrs 0.90 -0.13 1.83 1404.89 1.00 892 58 15 3 TRUE 1.13
colorectal cancer KRAS_G13D PALB2 54 20 >65yrs 0.40 -1.09 1.48 1588.14 1.00 578 53 19 1 TRUE 0.27
colorectal cancer KRAS_G13D PALB2 140 51 Age:overall 0.86 -0.28 1.90 1432.84 1.00 1656 131 42 9 TRUE 0.92
colorectal cancer KRAS_G13D CTCF 36 20 40-50yrs -0.17 -2.23 1.05 1184.72 1.00 399 35 19 1 FALSE 0.08
colorectal cancer KRAS_G13D CTCF 63 30 50-65yrs 1.09 -0.10 2.14 153.19 1.01 885 55 22 8 FALSE 1.16
colorectal cancer KRAS_G13D CTCF 54 32 >65yrs -0.76 -3.55 0.72 853.35 1.00 568 54 32 0 FALSE 0.29
colorectal cancer KRAS_G13D CTCF 153 82 Age:overall 0.07 -1.73 1.24 1418.72 1.00 1852 144 73 9 FALSE 0.03
colorectal cancer KRAS_G13D CDH1 66 22 50-65yrs -0.97 -3.78 0.60 771.02 1.01 989 66 22 0 TRUE 0.38
colorectal cancer KRAS_G13D CDH1 61 18 >65yrs -0.43 -2.30 1.00 939.09 1.00 648 59 16 2 TRUE 0.22
colorectal cancer KRAS_G13D CDH1 127 40 Age:overall -0.67 -2.85 0.88 919.14 1.00 1637 125 38 2 TRUE 0.30
colorectal cancer KRAS_G13D CDK12 36 13 40-50yrs -0.41 -2.26 0.58 392.13 1.01 402 36 13 0 FALSE 0.23
colorectal cancer KRAS_G13D CDK12 62 39 50-65yrs -0.02 -1.04 0.90 1114.99 1.00 876 57 34 5 FALSE 0.02
colorectal cancer KRAS_G13D CDK12 54 28 >65yrs -0.46 -2.51 0.51 292.01 1.02 574 54 28 0 FALSE 0.24
colorectal cancer KRAS_G13D CDK12 152 80 Age:overall -0.27 -1.64 0.61 399.99 1.02 1852 147 75 5 FALSE 0.19
colorectal cancer KRAS_G13D DNMT1 23 13 <40yrs 0.40 -0.49 1.30 1075.03 1.00 179 19 9 4 FALSE 0.42
colorectal cancer KRAS_G13D DNMT1 33 18 40-50yrs 0.26 -0.60 1.06 1023.42 1.00 391 31 16 2 FALSE 0.27
colorectal cancer KRAS_G13D DNMT1 61 36 50-65yrs 0.23 -0.59 0.97 1233.87 1.00 850 58 33 3 FALSE 0.25
colorectal cancer KRAS_G13D DNMT1 54 23 >65yrs 0.11 -0.88 0.89 1065.57 1.00 557 54 23 0 FALSE 0.09
colorectal cancer KRAS_G13D DNMT1 171 90 Age:overall 0.25 -0.52 0.97 1098.59 1.00 1977 162 81 9 FALSE 0.29
colorectal cancer KRAS_G13D BRD4 61 40 50-65yrs -0.31 -1.56 0.79 1213.59 1.00 874 58 37 3 FALSE 0.23
colorectal cancer KRAS_G13D BRD4 54 33 >65yrs -0.60 -2.12 0.53 1214.71 1.00 565 53 32 1 FALSE 0.43
colorectal cancer KRAS_G13D BRD4 115 73 Age:overall -0.44 -1.86 0.80 1326.87 1.00 1439 111 69 4 FALSE 0.27
colorectal cancer KRAS_G13D ASXL1 36 21 40-50yrs 0.15 -0.83 1.01 1328.74 1.00 397 34 19 2 TRUE 0.13
colorectal cancer KRAS_G13D ASXL1 61 40 50-65yrs 0.35 -0.50 1.22 1227.02 1.00 874 55 34 6 TRUE 0.37
colorectal cancer KRAS_G13D ASXL1 54 40 >65yrs -0.06 -1.16 0.78 1229.72 1.00 562 53 39 1 TRUE 0.04
colorectal cancer KRAS_G13D ASXL1 151 101 Age:overall 0.14 -0.74 0.94 1310.42 1.00 1833 142 92 9 TRUE 0.12
colorectal cancer KRAS_G13D EP300 23 15 <40yrs -0.18 -1.44 0.85 1650.33 1.00 183 22 14 1 TRUE 0.12
colorectal cancer KRAS_G13D EP300 37 16 40-50yrs 0.02 -1.16 1.07 1483.54 1.00 401 35 14 2 TRUE 0.01
colorectal cancer KRAS_G13D EP300 63 38 50-65yrs 0.38 -0.60 1.29 1544.10 1.00 880 57 32 6 TRUE 0.37
colorectal cancer KRAS_G13D EP300 54 56 >65yrs -0.51 -1.86 0.41 1619.99 1.00 552 53 55 1 TRUE 0.44
colorectal cancer KRAS_G13D EP300 177 125 Age:overall -0.08 -1.08 0.76 1663.59 1.00 2016 167 115 10 TRUE 0.06
colorectal cancer KRAS_G13D ERBB4 28 17 <40yrs 1.08 0.31 2.02 1324.05 1.00 203 21 10 7 TRUE 1.88
colorectal cancer KRAS_G13D ERBB4 37 20 40-50yrs 0.53 -0.44 1.27 1348.47 1.00 432 36 19 1 TRUE 0.65
colorectal cancer KRAS_G13D ERBB4 68 60 50-65yrs 0.90 0.27 1.58 1394.55 1.00 964 58 50 10 TRUE 2.24
colorectal cancer KRAS_G13D ERBB4 61 41 >65yrs 0.40 -0.62 1.12 1404.15 1.00 624 59 39 2 TRUE 0.43
colorectal cancer KRAS_G13D ERBB4 194 138 Age:overall 0.73 0.04 1.35 1383.68 1.00 2223 174 118 20 TRUE 1.52
colorectal cancer KRAS_G13D MDC1 62 30 50-65yrs 0.40 -0.71 1.33 1411.09 1.00 856 58 26 4 FALSE 0.34
colorectal cancer KRAS_G13D MDC1 54 19 >65yrs 0.10 -1.41 1.11 1293.44 1.00 561 53 18 1 FALSE 0.06
colorectal cancer KRAS_G13D MDC1 116 49 Age:overall 0.25 -1.11 1.33 1342.43 1.00 1417 111 44 5 FALSE 0.16
colorectal cancer KRAS_G13D RECQL4 23 13 <40yrs -0.27 -1.57 0.67 915.98 1.00 178 23 13 0 TRUE 0.18
colorectal cancer KRAS_G13D RECQL4 33 13 40-50yrs -0.16 -1.31 0.77 954.52 1.00 392 32 12 1 TRUE 0.12
colorectal cancer KRAS_G13D RECQL4 61 34 50-65yrs 0.03 -0.99 0.97 960.38 1.00 854 56 29 5 TRUE 0.02
colorectal cancer KRAS_G13D RECQL4 54 21 >65yrs -0.30 -1.65 0.63 1032.57 1.00 559 54 21 0 TRUE 0.21
colorectal cancer KRAS_G13D RECQL4 171 81 Age:overall -0.18 -1.28 0.65 838.08 1.00 1983 165 75 6 TRUE 0.14
colorectal cancer KRAS_G13D MED12 23 13 <40yrs 0.39 -0.40 1.13 1222.80 1.00 184 22 12 1 TRUE 0.48
colorectal cancer KRAS_G13D MED12 36 18 40-50yrs 0.49 -0.27 1.24 1190.42 1.00 400 33 15 3 TRUE 0.68
colorectal cancer KRAS_G13D MED12 64 35 50-65yrs 0.56 -0.19 1.32 1031.37 1.00 882 58 29 6 TRUE 0.88
colorectal cancer KRAS_G13D MED12 54 42 >65yrs 0.36 -0.46 1.07 1076.24 1.00 561 51 39 3 TRUE 0.45
colorectal cancer KRAS_G13D MED12 177 108 Age:overall 0.45 -0.28 1.12 1140.88 1.00 2027 164 95 13 TRUE 0.69
colorectal cancer KRAS_G13D ERCC5 33 13 40-50yrs -0.36 -1.63 0.85 1088.96 1.00 394 31 11 2 TRUE 0.25
colorectal cancer KRAS_G13D ERCC5 61 20 50-65yrs -0.46 -1.90 0.73 983.92 1.00 860 60 19 1 TRUE 0.33
colorectal cancer KRAS_G13D ERCC5 54 22 >65yrs -0.54 -2.06 0.61 926.44 1.00 559 54 22 0 TRUE 0.39
colorectal cancer KRAS_G13D ERCC5 148 55 Age:overall -0.45 -1.80 0.66 1037.07 1.00 1813 145 52 3 TRUE 0.33
colorectal cancer KRAS_G13D PIK3CD 33 17 40-50yrs -0.62 -2.39 0.63 1247.68 1.00 388 33 17 0 FALSE 0.38
colorectal cancer KRAS_G13D PIK3CD 61 18 50-65yrs -0.26 -1.68 0.93 1438.75 1.00 862 59 16 2 FALSE 0.16
colorectal cancer KRAS_G13D PIK3CD 54 31 >65yrs -0.41 -1.83 0.66 1475.63 1.00 554 52 29 2 FALSE 0.29
colorectal cancer KRAS_G13D PIK3CD 148 66 Age:overall -0.43 -1.90 0.67 1349.90 1.00 1804 144 62 4 FALSE 0.29
colorectal cancer KRAS_G13D BRCA1 28 19 <40yrs 1.66 0.78 2.56 1331.26 1.00 187 19 10 9 TRUE 3.60
colorectal cancer KRAS_G13D BRCA1 36 15 40-50yrs 0.84 -0.26 1.82 1420.32 1.00 403 34 13 2 TRUE 0.97
colorectal cancer KRAS_G13D BRCA1 62 19 50-65yrs 0.96 -0.04 1.81 1377.21 1.00 890 59 16 3 TRUE 1.40
colorectal cancer KRAS_G13D BRCA1 54 26 >65yrs 0.58 -0.48 1.50 1443.03 1.00 575 52 24 2 TRUE 0.61
colorectal cancer KRAS_G13D BRCA1 180 79 Age:overall 0.99 0.16 1.81 1304.27 1.00 2055 164 63 16 TRUE 1.73
colorectal cancer KRAS_G13D RBM10 61 38 50-65yrs -1.12 -2.93 0.28 215.38 1.01 871 60 37 1 FALSE 0.73
colorectal cancer KRAS_G13D RBM10 54 22 >65yrs -1.09 -2.96 0.38 273.59 1.01 578 53 21 1 FALSE 0.65
colorectal cancer KRAS_G13D RBM10 115 60 Age:overall -1.11 -2.97 0.36 235.93 1.01 1449 113 58 2 FALSE 0.68
colorectal cancer KRAS_G13D TSC1 62 23 50-65yrs 1.31 0.32 2.32 1445.66 1.00 891 56 17 6 TRUE 2.03
colorectal cancer KRAS_G13D TSC1 54 27 >65yrs 0.69 -0.55 1.63 1293.03 1.00 576 51 24 3 TRUE 0.66
colorectal cancer KRAS_G13D TSC1 116 50 Age:overall 0.98 -0.45 2.21 1379.61 1.00 1467 107 41 9 TRUE 0.82
colorectal cancer KRAS_G13D FLCN 61 23 50-65yrs -1.69 -4.66 0.38 154.10 1.02 889 60 22 1 TRUE 0.68
colorectal cancer KRAS_G13D FLCN 54 19 >65yrs -1.96 -5.02 0.18 221.68 1.02 576 54 19 0 TRUE 0.75
colorectal cancer KRAS_G13D FLCN 115 42 Age:overall -1.78 -4.82 0.38 167.79 1.02 1465 114 41 1 TRUE 0.71
colorectal cancer KRAS_G13D NF1 26 23 <40yrs 0.16 -0.69 1.00 1198.36 1.00 181 21 18 5 TRUE 0.14
colorectal cancer KRAS_G13D NF1 36 21 40-50yrs -0.16 -1.17 0.66 1255.92 1.00 402 35 20 1 TRUE 0.13
colorectal cancer KRAS_G13D NF1 61 58 50-65yrs -0.06 -0.83 0.65 1159.16 1.00 861 57 54 4 TRUE 0.05
colorectal cancer KRAS_G13D NF1 54 40 >65yrs -0.24 -1.22 0.54 1085.46 1.00 567 53 39 1 TRUE 0.23
colorectal cancer KRAS_G13D NF1 177 142 Age:overall -0.07 -0.87 0.60 1294.90 1.00 2011 166 131 11 TRUE 0.07
colorectal cancer KRAS_G13D FLT1 36 13 40-50yrs 0.14 -0.84 0.99 1175.61 1.00 405 35 12 1 FALSE 0.12
colorectal cancer KRAS_G13D FLT1 61 40 50-65yrs 0.20 -0.71 0.99 1191.49 1.00 877 57 36 4 FALSE 0.19
colorectal cancer KRAS_G13D FLT1 54 25 >65yrs 0.14 -0.81 0.94 877.48 1.00 577 52 23 2 FALSE 0.12
colorectal cancer KRAS_G13D FLT1 151 78 Age:overall 0.16 -0.71 0.97 1106.97 1.00 1859 144 71 7 FALSE 0.15
colorectal cancer KRAS_G13D RPTOR 36 16 40-50yrs -0.05 -1.26 0.89 1296.53 1.00 402 35 15 1 FALSE 0.03
colorectal cancer KRAS_G13D RPTOR 61 23 50-65yrs -0.08 -1.19 0.83 607.91 1.00 885 60 22 1 FALSE 0.06
colorectal cancer KRAS_G13D RPTOR 56 24 >65yrs 0.02 -1.08 0.92 642.14 1.00 575 53 21 3 FALSE 0.02
colorectal cancer KRAS_G13D RPTOR 153 63 Age:overall -0.04 -1.15 0.86 596.52 1.00 1862 148 58 5 FALSE 0.03
colorectal cancer KRAS_G13D RASA1 36 21 40-50yrs -0.60 -2.02 0.61 1417.27 1.00 401 34 19 2 FALSE 0.44
colorectal cancer KRAS_G13D RASA1 61 24 50-65yrs -0.69 -2.19 0.50 1534.49 1.00 889 60 23 1 FALSE 0.51
colorectal cancer KRAS_G13D RASA1 54 20 >65yrs -0.80 -2.27 0.41 1475.21 1.00 580 54 20 0 FALSE 0.59
colorectal cancer KRAS_G13D RASA1 151 65 Age:overall -0.70 -2.11 0.46 1499.38 1.00 1870 148 62 3 FALSE 0.54
colorectal cancer KRAS_G13D EPHA5 26 17 <40yrs 0.04 -1.19 1.33 860.33 1.00 182 21 12 5 FALSE 0.03
colorectal cancer KRAS_G13D EPHA5 36 27 40-50yrs -0.57 -1.84 0.39 1299.46 1.00 397 35 26 1 FALSE 0.49
colorectal cancer KRAS_G13D EPHA5 61 46 50-65yrs -0.50 -1.58 0.41 1260.86 1.00 868 59 44 2 FALSE 0.49
colorectal cancer KRAS_G13D EPHA5 54 54 >65yrs -0.89 -2.53 0.12 1327.07 1.00 549 54 54 0 FALSE 0.72
colorectal cancer KRAS_G13D EPHA5 177 144 Age:overall -0.48 -1.50 0.39 1040.39 1.00 1996 169 136 8 FALSE 0.49
colorectal cancer KRAS_G13D AR 36 22 40-50yrs -0.83 -3.34 0.43 1220.24 1.00 395 36 22 0 TRUE 0.39
colorectal cancer KRAS_G13D AR 62 38 50-65yrs 0.32 -0.82 1.37 914.73 1.00 874 56 32 6 TRUE 0.24
colorectal cancer KRAS_G13D AR 54 48 >65yrs -0.76 -2.59 0.39 1080.85 1.00 555 53 47 1 TRUE 0.52
colorectal cancer KRAS_G13D AR 152 108 Age:overall -0.42 -2.05 0.68 1421.23 1.00 1824 145 101 7 TRUE 0.26
colorectal cancer KRAS_G13D GNAS 37 16 40-50yrs 1.04 0.20 1.92 1212.97 1.00 435 33 12 4 TRUE 1.87
colorectal cancer KRAS_G13D GNAS 68 29 50-65yrs 1.09 0.36 1.82 1000.73 1.00 987 61 22 7 TRUE 2.48
colorectal cancer KRAS_G13D GNAS 61 25 >65yrs 0.74 -0.46 1.54 1042.19 1.00 638 60 24 1 TRUE 0.85
colorectal cancer KRAS_G13D GNAS 166 70 Age:overall 0.95 0.14 1.63 942.26 1.00 2060 154 58 12 TRUE 1.86
colorectal cancer KRAS_G13D ASXL2 36 16 40-50yrs -0.32 -1.60 0.77 534.48 1.00 405 36 16 0 FALSE 0.22
colorectal cancer KRAS_G13D ASXL2 61 26 50-65yrs -0.28 -1.54 0.77 544.86 1.00 887 60 25 1 FALSE 0.20
colorectal cancer KRAS_G13D ASXL2 55 20 >65yrs -0.18 -1.38 0.90 554.17 1.00 580 52 17 3 FALSE 0.12
colorectal cancer KRAS_G13D ASXL2 152 62 Age:overall -0.26 -1.44 0.86 510.08 1.00 1872 148 58 4 FALSE 0.18
colorectal cancer KRAS_G13D SF3B1 36 16 40-50yrs 1.17 0.37 1.86 995.11 1.00 404 34 14 2 TRUE 2.65
colorectal cancer KRAS_G13D SF3B1 61 24 50-65yrs 1.25 0.46 1.96 1074.95 1.00 891 56 19 5 TRUE 3.22
colorectal cancer KRAS_G13D SF3B1 60 24 >65yrs 1.29 0.57 1.99 940.84 1.00 579 53 17 7 TRUE 3.70
colorectal cancer KRAS_G13D SF3B1 157 64 Age:overall 1.23 0.47 1.90 1209.09 1.00 1874 143 50 14 TRUE 3.34
colorectal cancer KRAS_G13D MLH1 68 25 50-65yrs 1.24 0.11 2.21 1214.42 1.00 991 62 19 6 TRUE 1.69
colorectal cancer KRAS_G13D MLH1 61 12 >65yrs -0.51 -5.21 1.51 1096.09 1.00 650 61 12 0 TRUE 0.11
colorectal cancer KRAS_G13D MLH1 129 37 Age:overall 0.37 -2.83 2.14 1250.81 1.00 1641 123 31 6 TRUE 0.11
colorectal cancer KRAS_G13D ROS1 36 19 40-50yrs -0.21 -1.19 0.61 276.30 1.02 399 35 18 1 TRUE 0.18
colorectal cancer KRAS_G13D ROS1 61 43 50-65yrs -0.15 -1.10 0.64 349.34 1.02 876 57 39 4 TRUE 0.14
colorectal cancer KRAS_G13D ROS1 54 31 >65yrs -0.24 -1.25 0.57 223.35 1.02 570 53 30 1 TRUE 0.21
colorectal cancer KRAS_G13D ROS1 151 93 Age:overall -0.19 -1.17 0.54 261.16 1.02 1845 145 87 6 TRUE 0.18
colorectal cancer KRAS_G13D PIK3R2 36 11 40-50yrs 0.29 -0.93 1.34 1210.37 1.00 406 35 10 1 FALSE 0.20
colorectal cancer KRAS_G13D PIK3R2 61 13 50-65yrs 0.36 -0.80 1.41 973.38 1.00 895 59 11 2 FALSE 0.28
colorectal cancer KRAS_G13D PIK3R2 54 21 >65yrs 0.30 -0.91 1.28 929.74 1.00 578 52 19 2 FALSE 0.23
colorectal cancer KRAS_G13D PIK3R2 151 45 Age:overall 0.31 -0.78 1.32 1062.87 1.00 1879 146 40 5 FALSE 0.24
colorectal cancer KRAS_G13D FLT3 66 17 50-65yrs -0.42 -2.45 1.10 1036.60 1.00 994 65 16 1 TRUE 0.20
colorectal cancer KRAS_G13D FLT3 61 17 >65yrs -0.48 -2.39 0.97 1005.77 1.00 645 60 16 1 TRUE 0.24
colorectal cancer KRAS_G13D FLT3 127 34 Age:overall -0.42 -2.48 1.21 838.12 1.01 1639 125 32 2 TRUE 0.20
colorectal cancer KRAS_G13D MSH2 36 24 40-50yrs 0.12 -0.92 0.97 1332.26 1.00 401 35 23 1 TRUE 0.09
colorectal cancer KRAS_G13D MSH2 62 26 50-65yrs 0.25 -0.73 1.13 1351.54 1.00 886 59 23 3 TRUE 0.22
colorectal cancer KRAS_G13D MSH2 56 23 >65yrs 0.25 -0.65 1.05 1106.28 1.00 580 53 20 3 TRUE 0.23
colorectal cancer KRAS_G13D MSH2 154 73 Age:overall 0.20 -0.74 1.03 1259.77 1.00 1867 147 66 7 TRUE 0.17
colorectal cancer KRAS_G13D AXL 24 13 <40yrs 1.05 0.30 1.82 762.54 1.00 188 19 8 5 FALSE 2.13
colorectal cancer KRAS_G13D AXL 37 16 40-50yrs 0.84 0.09 1.53 1025.36 1.00 403 35 14 2 FALSE 1.75
colorectal cancer KRAS_G13D AXL 62 30 50-65yrs 0.95 0.27 1.63 881.95 1.00 886 56 24 6 FALSE 2.33
colorectal cancer KRAS_G13D AXL 55 29 >65yrs 0.74 -0.07 1.40 916.26 1.00 570 53 27 2 FALSE 1.32
colorectal cancer KRAS_G13D AXL 178 88 Age:overall 0.90 0.23 1.53 887.71 1.00 2047 163 73 15 FALSE 2.24
colorectal cancer KRAS_G13D PIK3CG 36 22 40-50yrs -0.68 -1.99 0.36 1218.39 1.00 397 36 22 0 FALSE 0.59
colorectal cancer KRAS_G13D PIK3CG 62 37 50-65yrs -0.55 -1.68 0.41 1290.04 1.00 876 60 35 2 FALSE 0.52
colorectal cancer KRAS_G13D PIK3CG 54 42 >65yrs -0.50 -1.55 0.42 1268.26 1.00 559 51 39 3 FALSE 0.48
colorectal cancer KRAS_G13D PIK3CG 152 101 Age:overall -0.57 -1.70 0.34 1258.86 1.00 1832 147 96 5 FALSE 0.56
colorectal cancer KRAS_G13D MAP2K4 36 11 40-50yrs 0.48 -0.46 1.30 1322.70 1.00 404 35 10 1 TRUE 0.53
colorectal cancer KRAS_G13D MAP2K4 61 29 50-65yrs 0.51 -0.39 1.31 1340.88 1.00 882 58 26 3 TRUE 0.63
colorectal cancer KRAS_G13D MAP2K4 55 18 >65yrs 0.53 -0.43 1.36 1313.20 1.00 580 52 15 3 TRUE 0.62
colorectal cancer KRAS_G13D MAP2K4 152 58 Age:overall 0.50 -0.40 1.31 1303.98 1.00 1866 145 51 7 TRUE 0.62
colorectal cancer KRAS_G13D EGFR 37 12 40-50yrs -0.38 -1.98 0.75 39.09 1.06 438 35 10 2 TRUE 0.22
colorectal cancer KRAS_G13D EGFR 66 27 50-65yrs -0.48 -2.06 0.64 32.27 1.07 984 65 26 1 TRUE 0.28
colorectal cancer KRAS_G13D EGFR 61 23 >65yrs -0.55 -2.25 0.63 35.16 1.07 640 61 23 0 TRUE 0.32
colorectal cancer KRAS_G13D EGFR 164 62 Age:overall -0.47 -2.03 0.64 33.30 1.07 2062 161 59 3 TRUE 0.29
colorectal cancer KRAS_G13D ARID1B 23 11 <40yrs 0.12 -0.69 1.03 1387.34 1.00 190 20 8 3 TRUE 0.10
colorectal cancer KRAS_G13D ARID1B 36 22 40-50yrs -0.12 -1.10 0.65 1340.32 1.00 399 36 22 0 TRUE 0.11
colorectal cancer KRAS_G13D ARID1B 61 54 50-65yrs 0.01 -0.78 0.74 1400.78 1.00 864 57 50 4 TRUE 0.01
colorectal cancer KRAS_G13D ARID1B 54 53 >65yrs -0.01 -0.79 0.68 1219.42 1.00 550 50 49 4 TRUE 0.01
colorectal cancer KRAS_G13D ARID1B 174 140 Age:overall 0.00 -0.74 0.66 1411.79 1.00 2003 163 129 11 TRUE 0.00
colorectal cancer KRAS_G13D ARID5B 36 20 40-50yrs -2.08 -4.65 -0.19 275.88 1.01 403 36 20 0 FALSE 1.05
colorectal cancer KRAS_G13D ARID5B 61 22 50-65yrs -2.08 -4.66 -0.16 290.03 1.01 886 61 22 0 FALSE 1.06
colorectal cancer KRAS_G13D ARID5B 54 17 >65yrs -1.96 -4.35 -0.04 246.89 1.01 581 53 16 1 FALSE 0.99
colorectal cancer KRAS_G13D ARID5B 151 59 Age:overall -2.03 -4.48 -0.17 259.94 1.01 1870 150 58 1 FALSE 1.05
colorectal cancer KRAS_G13D BRAF 24 21 <40yrs -0.92 -1.91 0.05 1279.46 1.00 194 22 19 2 TRUE 1.17
colorectal cancer KRAS_G13D BRAF 37 34 40-50yrs -1.07 -2.13 -0.16 1369.31 1.00 416 36 33 1 TRUE 1.50
colorectal cancer KRAS_G13D BRAF 66 93 50-65yrs -0.99 -1.91 -0.18 1633.14 1.00 920 63 90 3 TRUE 1.64
colorectal cancer KRAS_G13D BRAF 61 105 >65yrs -1.18 -2.12 -0.36 1335.71 1.00 565 59 103 2 TRUE 2.02
colorectal cancer KRAS_G13D BRAF 188 253 Age:overall -1.03 -1.95 -0.26 1435.06 1.00 2095 180 245 8 TRUE 1.83
colorectal cancer KRAS_G13D B2M 24 12 <40yrs 0.57 -0.29 1.41 396.17 1.01 180 20 8 4 FALSE 0.75
colorectal cancer KRAS_G13D B2M 34 21 40-50yrs 0.46 -0.28 1.19 500.41 1.01 394 31 18 3 FALSE 0.63
colorectal cancer KRAS_G13D B2M 63 52 50-65yrs 0.41 -0.28 1.06 471.16 1.00 847 58 47 5 FALSE 0.64
colorectal cancer KRAS_G13D B2M 56 54 >65yrs 0.32 -0.40 0.98 715.01 1.00 549 52 50 4 FALSE 0.44
colorectal cancer KRAS_G13D B2M 177 139 Age:overall 0.44 -0.25 1.05 440.34 1.01 1970 161 123 16 FALSE 0.71
colorectal cancer KRAS_G13D TGFBR1 24 11 <40yrs 0.44 -0.89 1.55 918.87 1.00 179 22 9 2 FALSE 0.31
colorectal cancer KRAS_G13D TGFBR1 61 18 50-65yrs 0.36 -0.86 1.40 898.59 1.00 865 59 16 2 FALSE 0.26
colorectal cancer KRAS_G13D TGFBR1 54 13 >65yrs 0.23 -1.14 1.34 924.12 1.00 567 53 12 1 FALSE 0.14
colorectal cancer KRAS_G13D TGFBR1 139 42 Age:overall 0.35 -0.87 1.41 894.56 1.00 1611 134 37 5 FALSE 0.25
colorectal cancer KRAS_G13D TET2 27 16 <40yrs 1.00 0.06 2.12 1364.68 1.00 186 20 9 7 TRUE 1.27
colorectal cancer KRAS_G13D TET2 36 19 40-50yrs 0.21 -1.01 1.12 1279.74 1.00 401 35 18 1 TRUE 0.16
colorectal cancer KRAS_G13D TET2 61 29 50-65yrs 0.13 -1.09 1.04 1273.53 1.00 881 60 28 1 TRUE 0.09
colorectal cancer KRAS_G13D TET2 54 27 >65yrs 0.24 -0.87 1.12 1367.65 1.00 575 52 25 2 TRUE 0.20
colorectal cancer KRAS_G13D TET2 178 91 Age:overall 0.39 -0.50 1.20 1393.16 1.00 2043 167 80 11 TRUE 0.43
colorectal cancer KRAS_G13D PDGFRB 36 11 40-50yrs 0.27 -1.13 1.43 1517.76 1.00 404 35 10 1 TRUE 0.17
colorectal cancer KRAS_G13D PDGFRB 61 11 50-65yrs 0.44 -0.83 1.60 1306.95 1.00 897 59 9 2 TRUE 0.30
colorectal cancer KRAS_G13D PDGFRB 54 24 >65yrs 0.19 -1.05 1.20 1265.91 1.00 573 52 22 2 TRUE 0.13
colorectal cancer KRAS_G13D PDGFRB 151 46 Age:overall 0.29 -0.98 1.44 1364.55 1.00 1874 146 41 5 TRUE 0.21
colorectal cancer KRAS_G13D CARD11 23 21 <40yrs 0.34 -0.66 1.33 1287.64 1.00 179 19 17 4 FALSE 0.30
colorectal cancer KRAS_G13D CARD11 36 20 40-50yrs -0.41 -2.35 0.74 1117.38 1.00 396 36 20 0 FALSE 0.20
colorectal cancer KRAS_G13D CARD11 64 45 50-65yrs 0.62 -0.29 1.54 1288.01 1.00 870 56 37 8 FALSE 0.76
colorectal cancer KRAS_G13D CARD11 54 42 >65yrs -0.62 -2.71 0.54 1093.80 1.00 558 54 42 0 FALSE 0.31
colorectal cancer KRAS_G13D CARD11 177 128 Age:overall -0.02 -1.18 0.85 1080.14 1.00 2003 165 116 12 FALSE 0.01
colorectal cancer KRAS_G13D DNMT3A 36 11 40-50yrs 0.47 -0.67 1.40 1261.66 1.00 407 34 9 2 TRUE 0.45
colorectal cancer KRAS_G13D DNMT3A 62 21 50-65yrs 0.48 -0.51 1.35 1241.22 1.00 888 59 18 3 TRUE 0.49
colorectal cancer KRAS_G13D DNMT3A 54 19 >65yrs 0.41 -0.72 1.25 1183.18 1.00 581 53 18 1 TRUE 0.37
colorectal cancer KRAS_G13D DNMT3A 152 51 Age:overall 0.44 -0.63 1.30 1092.44 1.00 1876 146 45 6 TRUE 0.44
colorectal cancer KRAS_G13D MSH6 23 12 <40yrs 0.01 -0.97 0.80 853.66 1.00 184 22 11 1 TRUE 0.01
colorectal cancer KRAS_G13D MSH6 37 24 40-50yrs 0.02 -0.91 0.79 934.21 1.00 396 35 22 2 TRUE 0.01
colorectal cancer KRAS_G13D MSH6 61 38 50-65yrs 0.01 -0.88 0.76 847.01 1.00 881 58 35 3 TRUE 0.01
colorectal cancer KRAS_G13D MSH6 55 26 >65yrs -0.01 -0.94 0.72 756.13 1.00 573 53 24 2 TRUE 0.01
colorectal cancer KRAS_G13D MSH6 176 100 Age:overall 0.00 -0.91 0.72 684.77 1.00 2034 168 92 8 TRUE 0.00
colorectal cancer KRAS_G13D SOX9 23 22 <40yrs 0.53 -0.04 1.09 1221.01 1.00 178 19 18 4 FALSE 1.26
colorectal cancer KRAS_G13D SOX9 36 41 40-50yrs 0.42 -0.21 0.91 1253.94 1.00 376 34 39 2 FALSE 0.86
colorectal cancer KRAS_G13D SOX9 63 114 50-65yrs 0.57 0.15 1.06 948.27 1.00 820 49 100 14 FALSE 1.85
colorectal cancer KRAS_G13D SOX9 54 87 >65yrs 0.54 0.04 1.02 1029.54 1.00 525 43 76 11 FALSE 1.55
colorectal cancer KRAS_G13D SOX9 176 264 Age:overall 0.52 0.09 0.96 1014.62 1.00 1899 145 233 31 FALSE 1.64
colorectal cancer KRAS_G13D ETV1 61 15 50-65yrs 0.67 -0.63 1.80 1545.81 1.00 867 59 13 2 TRUE 0.55
colorectal cancer KRAS_G13D ETV1 55 23 >65yrs 0.78 -0.31 1.69 1142.29 1.00 561 51 19 4 TRUE 0.87
colorectal cancer KRAS_G13D ETV1 116 38 Age:overall 0.71 -0.78 2.11 1346.45 1.00 1428 110 32 6 TRUE 0.50
colorectal cancer KRAS_G13D ARAF 62 22 50-65yrs 0.62 -0.72 1.80 1132.12 1.00 890 58 18 4 FALSE 0.45
colorectal cancer KRAS_G13D ARAF 54 23 >65yrs -1.22 -5.66 0.80 626.64 1.01 574 54 23 0 FALSE 0.29
colorectal cancer KRAS_G13D ARAF 116 45 Age:overall -0.24 -3.16 1.80 1375.05 1.00 1464 112 41 4 FALSE 0.07
colorectal cancer KRAS_G13D SMAD2 36 33 40-50yrs 0.02 -1.04 0.88 586.59 1.01 390 34 31 2 TRUE 0.01
colorectal cancer KRAS_G13D SMAD2 62 39 50-65yrs 0.31 -0.59 1.12 1415.53 1.00 875 57 34 5 TRUE 0.31
colorectal cancer KRAS_G13D SMAD2 54 20 >65yrs -0.03 -1.31 0.86 579.06 1.01 576 53 19 1 TRUE 0.02
colorectal cancer KRAS_G13D SMAD2 152 92 Age:overall 0.09 -0.92 0.94 982.12 1.01 1841 144 84 8 TRUE 0.07
colorectal cancer KRAS_G13D JUN 33 11 40-50yrs -0.89 -2.87 0.50 697.36 1.00 393 33 11 0 FALSE 0.47
colorectal cancer KRAS_G13D JUN 61 18 50-65yrs -0.89 -2.97 0.48 615.80 1.00 861 61 18 0 FALSE 0.51
colorectal cancer KRAS_G13D JUN 54 19 >65yrs -0.76 -2.59 0.59 565.33 1.00 564 52 17 2 FALSE 0.44
colorectal cancer KRAS_G13D JUN 148 48 Age:overall -0.84 -2.65 0.52 547.33 1.00 1818 146 46 2 FALSE 0.50
colorectal cancer KRAS_G13D DNMT3B 23 12 <40yrs -0.67 -3.96 0.87 1024.78 1.00 180 23 12 0 FALSE 0.22
colorectal cancer KRAS_G13D DNMT3B 61 28 50-65yrs 0.46 -0.80 1.64 1043.55 1.00 856 56 23 5 FALSE 0.34
colorectal cancer KRAS_G13D DNMT3B 54 15 >65yrs -0.71 -3.68 0.89 1240.74 1.00 565 54 15 0 FALSE 0.26
colorectal cancer KRAS_G13D DNMT3B 138 55 Age:overall -0.29 -2.34 1.04 1195.17 1.00 1601 133 50 5 FALSE 0.13
colorectal cancer KRAS_G13D FGFR1 37 12 40-50yrs -1.62 -4.33 0.34 1237.54 1.00 437 36 11 1 TRUE 0.75
colorectal cancer KRAS_G13D FGFR1 66 21 50-65yrs -1.75 -4.50 0.13 1233.15 1.00 990 66 21 0 TRUE 0.83
colorectal cancer KRAS_G13D FGFR1 61 11 >65yrs -1.74 -4.56 0.12 1284.26 1.00 650 61 11 0 TRUE 0.81
colorectal cancer KRAS_G13D FGFR1 164 44 Age:overall -1.69 -4.42 0.16 1241.47 1.00 2077 163 43 1 TRUE 0.81
colorectal cancer KRAS_G13D MITF 61 25 50-65yrs -0.63 -2.59 0.79 1575.72 1.00 883 60 24 1 FALSE 0.35
colorectal cancer KRAS_G13D MITF 54 14 >65yrs -0.59 -2.60 0.88 1568.68 1.00 582 53 13 1 FALSE 0.30
colorectal cancer KRAS_G13D MITF 115 39 Age:overall -0.61 -2.50 0.93 1554.87 1.00 1465 113 37 2 FALSE 0.31
colorectal cancer KRAS_G13D SH2B3 55 25 50-65yrs -0.61 -2.48 0.85 1092.71 1.00 807 53 23 2 FALSE 0.34
colorectal cancer KRAS_G13D SH2B3 47 19 >65yrs -1.05 -3.45 0.50 1185.41 1.00 529 47 19 0 FALSE 0.44
colorectal cancer KRAS_G13D SH2B3 102 44 Age:overall -0.80 -2.87 0.67 1137.31 1.00 1336 100 42 2 FALSE 0.41
colorectal cancer KRAS_G13D GLI1 36 17 40-50yrs -0.26 -1.25 0.73 48.78 1.06 365 34 15 2 FALSE 0.21
colorectal cancer KRAS_G13D GLI1 55 36 50-65yrs -0.29 -1.28 0.71 44.51 1.06 795 53 34 2 FALSE 0.24
colorectal cancer KRAS_G13D GLI1 47 25 >65yrs -0.30 -1.30 0.69 54.76 1.05 525 46 24 1 FALSE 0.25
colorectal cancer KRAS_G13D GLI1 138 78 Age:overall -0.28 -1.30 0.68 56.12 1.06 1685 133 73 5 FALSE 0.24
colorectal cancer KRAS_G13D ZFHX3 23 28 <40yrs 0.32 -0.50 1.29 1317.12 1.00 165 16 21 7 FALSE 0.33
colorectal cancer KRAS_G13D ZFHX3 35 32 40-50yrs -0.19 -1.07 0.63 1417.06 1.00 354 33 30 2 FALSE 0.18
colorectal cancer KRAS_G13D ZFHX3 56 82 50-65yrs -0.20 -0.99 0.53 1314.88 1.00 771 52 78 4 FALSE 0.21
colorectal cancer KRAS_G13D ZFHX3 48 84 >65yrs -0.35 -1.20 0.34 1475.75 1.00 493 45 81 3 FALSE 0.43
colorectal cancer KRAS_G13D ZFHX3 162 226 Age:overall -0.10 -0.80 0.57 1502.33 1.00 1783 146 210 16 FALSE 0.11
colorectal cancer KRAS_G13D MST1R 55 26 50-65yrs 0.85 -0.31 1.97 1610.00 1.00 779 50 21 5 FALSE 0.84
colorectal cancer KRAS_G13D MST1R 47 33 >65yrs -0.46 -2.50 0.84 1442.44 1.00 507 46 32 1 FALSE 0.23
colorectal cancer KRAS_G13D MST1R 102 59 Age:overall 0.21 -1.99 2.02 1456.61 1.00 1286 96 53 6 FALSE 0.08
colorectal cancer KRAS_G13D MGA 24 18 <40yrs 1.25 0.24 2.43 1247.83 1.00 173 16 10 8 FALSE 1.62
colorectal cancer KRAS_G13D MGA 35 19 40-50yrs -0.08 -1.63 1.00 1377.27 1.00 362 35 19 0 FALSE 0.04
colorectal cancer KRAS_G13D MGA 55 41 50-65yrs 0.56 -0.26 1.39 1112.62 1.00 791 50 36 5 FALSE 0.75
colorectal cancer KRAS_G13D MGA 47 45 >65yrs 0.02 -1.10 0.91 1312.01 1.00 508 45 43 2 FALSE 0.02
colorectal cancer KRAS_G13D MGA 161 123 Age:overall 0.43 -0.62 1.29 1356.69 1.00 1834 146 108 15 FALSE 0.45
colorectal cancer KRAS_G13D TCF3 32 12 40-50yrs 0.14 -1.15 1.05 790.05 1.00 356 32 12 0 FALSE 0.09
colorectal cancer KRAS_G13D TCF3 55 26 50-65yrs 0.38 -0.56 1.38 733.30 1.01 779 50 21 5 FALSE 0.37
colorectal cancer KRAS_G13D TCF3 47 22 >65yrs 0.16 -1.00 1.03 797.76 1.00 511 46 21 1 FALSE 0.12
colorectal cancer KRAS_G13D TCF3 134 60 Age:overall 0.23 -0.80 1.07 804.47 1.00 1646 128 54 6 FALSE 0.19
colorectal cancer KRAS_G13D KMT2B 9 25 <40yrs 0.58 -0.65 1.73 1465.62 1.00 90 6 22 3 FALSE 0.45
colorectal cancer KRAS_G13D KMT2B 23 17 40-50yrs 0.88 -0.21 1.98 1469.00 1.00 215 19 13 4 FALSE 0.92
colorectal cancer KRAS_G13D KMT2B 38 59 50-65yrs 1.34 0.57 2.04 1249.33 1.00 435 25 46 13 FALSE 3.33
colorectal cancer KRAS_G13D KMT2B 26 81 >65yrs -0.83 -2.33 0.27 1333.58 1.00 267 25 80 1 FALSE 0.66
colorectal cancer KRAS_G13D KMT2B 96 182 Age:overall 0.48 -0.66 1.57 1655.26 1.00 1007 75 161 21 FALSE 0.41
colorectal cancer KRAS_G13D TCF7L2 21 34 <40yrs 0.13 -0.42 0.68 1119.66 1.00 153 17 30 4 FALSE 0.20
colorectal cancer KRAS_G13D TCF7L2 37 56 40-50yrs 0.17 -0.35 0.68 1113.05 1.00 332 29 48 8 FALSE 0.27
colorectal cancer KRAS_G13D TCF7L2 55 121 50-65yrs 0.08 -0.44 0.58 830.83 1.00 725 48 114 7 FALSE 0.12
colorectal cancer KRAS_G13D TCF7L2 48 88 >65yrs 0.08 -0.44 0.56 965.78 1.00 469 42 82 6 FALSE 0.12
colorectal cancer KRAS_G13D TCF7L2 161 299 Age:overall 0.12 -0.38 0.59 1007.76 1.00 1679 136 274 25 FALSE 0.19
colorectal cancer KRAS_G13D MSH3 8 12 <40yrs 0.18 -1.08 1.55 1386.86 1.00 95 6 10 2 FALSE 0.10
colorectal cancer KRAS_G13D MSH3 35 31 50-65yrs 0.18 -0.98 1.27 1379.86 1.00 438 31 27 4 FALSE 0.12
colorectal cancer KRAS_G13D MSH3 26 39 >65yrs -0.54 -2.43 0.66 1194.56 1.00 285 26 39 0 FALSE 0.30
colorectal cancer KRAS_G13D MSH3 69 82 Age:overall -0.06 -1.27 1.02 1282.00 1.01 818 63 76 6 FALSE 0.04
colorectal cancer KRAS_G13D ANKRD11 20 21 <40yrs 0.56 -0.26 1.48 1543.99 1.00 163 15 16 5 FALSE 0.70
colorectal cancer KRAS_G13D ANKRD11 33 14 40-50yrs 0.42 -0.45 1.40 1499.66 1.00 357 30 11 3 FALSE 0.44
colorectal cancer KRAS_G13D ANKRD11 56 61 50-65yrs 0.17 -0.64 0.85 1528.53 1.00 759 52 57 4 FALSE 0.18
colorectal cancer KRAS_G13D ANKRD11 47 50 >65yrs -0.01 -1.00 0.73 1453.75 1.00 490 45 48 2 FALSE 0.01
colorectal cancer KRAS_G13D ANKRD11 156 146 Age:overall 0.28 -0.49 0.98 1641.77 1.00 1769 142 132 14 FALSE 0.35
colorectal cancer KRAS_G13D PGR 55 24 50-65yrs -1.67 -4.76 0.34 344.61 1.00 777 54 23 1 FALSE 0.72
colorectal cancer KRAS_G13D PGR 47 24 >65yrs -2.03 -5.66 0.01 505.48 1.00 507 47 24 0 FALSE 0.78
colorectal cancer KRAS_G13D PGR 102 48 Age:overall -1.82 -5.11 0.29 439.41 1.00 1284 101 47 1 FALSE 0.74
colorectal cancer KRAS_G13D PLCG2 33 14 40-50yrs -0.03 -1.19 1.00 1479.27 1.00 355 31 12 2 FALSE 0.02
colorectal cancer KRAS_G13D PLCG2 55 27 50-65yrs -0.16 -1.34 0.79 1376.17 1.00 775 54 26 1 FALSE 0.12
colorectal cancer KRAS_G13D PLCG2 48 35 >65yrs -0.05 -1.10 0.84 1540.28 1.00 500 45 32 3 FALSE 0.04
colorectal cancer KRAS_G13D PLCG2 136 76 Age:overall -0.08 -1.11 0.85 1425.17 1.00 1630 130 70 6 FALSE 0.06
colorectal cancer KRAS_G13D POLD1 20 12 <40yrs 0.34 -0.60 1.26 1364.56 1.00 174 18 10 2 TRUE 0.33
colorectal cancer KRAS_G13D POLD1 37 16 40-50yrs 0.45 -0.40 1.34 1441.98 1.00 366 33 12 4 TRUE 0.50
colorectal cancer KRAS_G13D POLD1 55 39 50-65yrs 0.33 -0.49 1.18 1369.44 1.00 799 51 35 4 TRUE 0.38
colorectal cancer KRAS_G13D POLD1 47 45 >65yrs 0.02 -1.04 0.82 1108.05 1.00 515 46 44 1 TRUE 0.02
colorectal cancer KRAS_G13D POLD1 159 112 Age:overall 0.29 -0.52 1.08 1389.08 1.00 1854 148 101 11 TRUE 0.33
colorectal cancer KRAS_G13D INHBA 55 26 50-65yrs -4.54 -11.60 -0.83 105.82 1.04 802 55 26 0 FALSE 1.07
colorectal cancer KRAS_G13D INHBA 47 19 >65yrs -4.53 -11.27 -0.68 98.25 1.04 528 47 19 0 FALSE 1.07
colorectal cancer KRAS_G13D INHBA 102 45 Age:overall -4.50 -11.36 -0.61 89.83 1.04 1330 102 45 0 FALSE 1.08
colorectal cancer KRAS_G13D PREX2 23 21 40-50yrs 0.12 -0.74 0.96 440.26 1.00 214 20 18 3 FALSE 0.11
colorectal cancer KRAS_G13D PREX2 37 34 50-65yrs 0.17 -0.63 1.01 307.26 1.01 436 32 29 5 FALSE 0.16
colorectal cancer KRAS_G13D PREX2 26 29 >65yrs -0.03 -1.20 0.89 779.71 1.00 292 26 29 0 FALSE 0.02
colorectal cancer KRAS_G13D PREX2 86 84 Age:overall 0.08 -0.80 0.92 480.30 1.00 942 78 76 8 FALSE 0.07
colorectal cancer KRAS_G13D AMER1 24 13 <40yrs 1.14 0.21 2.26 1345.51 1.00 188 19 8 5 FALSE 1.46
colorectal cancer KRAS_G13D AMER1 38 33 40-50yrs 0.32 -0.68 1.21 1429.85 1.00 384 35 30 3 FALSE 0.30
colorectal cancer KRAS_G13D AMER1 63 53 50-65yrs 1.25 0.52 1.97 1462.34 1.00 866 51 41 12 FALSE 3.04
colorectal cancer KRAS_G13D AMER1 54 70 >65yrs -0.32 -1.58 0.61 1694.42 1.00 533 52 68 2 FALSE 0.24
colorectal cancer KRAS_G13D AMER1 179 169 Age:overall 0.61 -0.32 1.45 1370.58 1.00 1971 157 147 22 FALSE 0.75
colorectal cancer KRAS_G13D HLA-A 56 17 50-65yrs 0.96 -0.32 2.12 963.36 1.00 786 52 13 4 FALSE 0.91
colorectal cancer KRAS_G13D HLA-A 47 20 >65yrs 0.15 -1.82 1.39 608.18 1.00 513 46 19 1 FALSE 0.06
colorectal cancer KRAS_G13D HLA-A 103 37 Age:overall 0.56 -1.28 2.04 1065.05 1.00 1299 98 32 5 FALSE 0.29
colorectal cancer KRAS_G13D EPHA7 35 13 40-50yrs -0.66 -2.09 0.37 1430.11 1.00 365 35 13 0 FALSE 0.53
colorectal cancer KRAS_G13D EPHA7 56 39 50-65yrs -0.52 -1.82 0.47 1528.18 1.00 795 53 36 3 FALSE 0.44
colorectal cancer KRAS_G13D EPHA7 47 30 >65yrs -0.62 -1.89 0.40 1481.51 1.00 521 46 29 1 FALSE 0.54
colorectal cancer KRAS_G13D EPHA7 138 82 Age:overall -0.60 -1.92 0.38 1463.01 1.00 1681 134 78 4 FALSE 0.54
colorectal cancer KRAS_G13D NCOA3 55 19 50-65yrs -0.34 -2.27 1.24 558.17 1.01 812 53 17 2 TRUE 0.15
colorectal cancer KRAS_G13D NCOA3 47 23 >65yrs -1.41 -5.09 0.44 1361.57 1.00 525 47 23 0 TRUE 0.47
colorectal cancer KRAS_G13D NCOA3 102 42 Age:overall -0.85 -3.50 1.06 1376.36 1.00 1337 100 40 2 TRUE 0.33
colorectal cancer KRAS_G13D SLX4 34 16 50-65yrs 0.12 -1.33 1.36 1415.49 1.00 421 32 14 2 FALSE 0.07
colorectal cancer KRAS_G13D SLX4 26 18 >65yrs -0.09 -1.73 1.21 1378.01 1.00 289 25 17 1 FALSE 0.05
colorectal cancer KRAS_G13D SLX4 60 34 Age:overall 0.02 -1.62 1.43 1447.71 1.00 710 57 31 3 FALSE 0.01
colorectal cancer KRAS_G13D INPPL1 19 12 40-50yrs 0.36 -0.95 1.27 1063.75 1.00 205 18 11 1 FALSE 0.28
colorectal cancer KRAS_G13D INPPL1 36 29 50-65yrs 0.72 -0.21 1.74 895.69 1.00 417 29 22 7 FALSE 0.88
colorectal cancer KRAS_G13D INPPL1 26 25 >65yrs 0.09 -1.98 1.08 907.64 1.00 286 26 25 0 FALSE 0.04
colorectal cancer KRAS_G13D INPPL1 81 66 Age:overall 0.39 -0.82 1.28 1058.32 1.00 908 73 58 8 FALSE 0.34
melanoma NRAS_Q61K SPEN 28 35 50-65yrs -0.30 -1.58 0.81 1416.88 1.00 296 25 32 3 FALSE 0.21
melanoma NRAS_Q61K SPEN 25 70 >65yrs -0.60 -1.97 0.47 1382.52 1.00 370 23 68 2 FALSE 0.49
melanoma NRAS_Q61K SPEN 53 105 Age:overall -0.44 -1.88 0.93 1421.84 1.00 666 48 100 5 FALSE 0.28
melanoma NRAS_Q61K KMT2C 27 55 50-65yrs -1.04 -2.25 0.06 1349.88 1.00 260 25 53 2 FALSE 1.07
melanoma NRAS_Q61K KMT2C 23 79 >65yrs -1.05 -2.32 0.04 1276.68 1.00 338 21 77 2 FALSE 1.06
melanoma NRAS_Q61K KMT2C 50 134 Age:overall -1.04 -2.38 0.18 1362.59 1.00 598 46 130 4 FALSE 0.88
melanoma NRAS_Q61K TP53 7 13 <40yrs 0.50 -0.32 1.38 684.80 1.00 66 3 9 4 TRUE 0.65
melanoma NRAS_Q61K TP53 29 72 50-65yrs 0.38 -0.32 1.01 529.94 1.00 267 22 65 7 TRUE 0.57
melanoma NRAS_Q61K TP53 25 105 >65yrs 0.32 -0.37 0.90 636.12 1.00 337 19 99 6 TRUE 0.47
melanoma NRAS_Q61K TP53 66 210 Age:overall 0.38 -0.34 1.02 552.10 1.00 739 48 192 18 TRUE 0.59
melanoma NRAS_Q61K ATRX 6 12 <40yrs -0.32 -1.58 0.67 915.21 1.00 66 6 12 0 TRUE 0.25
melanoma NRAS_Q61K ATRX 28 40 50-65yrs -0.39 -1.69 0.54 845.01 1.00 292 28 40 0 TRUE 0.31
melanoma NRAS_Q61K ATRX 25 43 >65yrs -0.17 -1.19 0.68 1328.88 1.00 379 21 39 4 TRUE 0.14
melanoma NRAS_Q61K ATRX 64 108 Age:overall -0.26 -1.27 0.59 1115.13 1.00 814 58 102 6 TRUE 0.24
melanoma NRAS_Q61K ATR 28 20 50-65yrs -1.00 -2.99 0.54 1116.10 1.00 302 27 19 1 FALSE 0.57
melanoma NRAS_Q61K ATR 25 40 >65yrs -1.03 -2.97 0.39 950.90 1.00 379 24 39 1 FALSE 0.63
melanoma NRAS_Q61K ATR 53 60 Age:overall -1.01 -3.07 0.66 1149.98 1.00 681 51 58 2 FALSE 0.53
melanoma NRAS_Q61K PDGFRA 28 20 50-65yrs -1.06 -3.01 0.49 1086.61 1.00 308 27 19 1 TRUE 0.59
melanoma NRAS_Q61K PDGFRA 25 51 >65yrs -1.23 -3.23 0.27 1395.32 1.00 378 24 50 1 TRUE 0.79
melanoma NRAS_Q61K PDGFRA 53 71 Age:overall -1.12 -3.28 0.76 1479.17 1.00 686 51 69 2 TRUE 0.56
melanoma NRAS_Q61K NSD1 28 18 50-65yrs -1.29 -4.45 0.50 1243.40 1.00 302 28 18 0 FALSE 0.41
melanoma NRAS_Q61K NSD1 25 35 >65yrs -0.67 -2.38 0.75 1386.87 1.00 385 23 33 2 FALSE 0.39
melanoma NRAS_Q61K NSD1 53 53 Age:overall -0.97 -3.26 0.71 1322.41 1.00 687 51 51 2 FALSE 0.42
melanoma NRAS_Q61K FLT4 28 23 50-65yrs -1.24 -3.29 0.44 1396.51 1.00 300 27 22 1 TRUE 0.72
melanoma NRAS_Q61K FLT4 25 60 >65yrs -1.43 -3.41 0.09 1229.16 1.00 367 24 59 1 TRUE 0.97
melanoma NRAS_Q61K FLT4 53 83 Age:overall -1.30 -3.37 0.38 1248.52 1.00 667 51 81 2 TRUE 0.72
melanoma NRAS_Q61K PTPRD 6 17 <40yrs -0.58 -1.71 0.70 1563.57 1.00 64 4 15 2 FALSE 0.47
melanoma NRAS_Q61K PTPRD 28 73 50-65yrs -0.96 -2.00 -0.10 1457.05 1.00 267 26 71 2 FALSE 1.29
melanoma NRAS_Q61K PTPRD 26 170 >65yrs -0.81 -1.66 -0.06 1420.99 1.00 319 21 165 5 FALSE 1.27
melanoma NRAS_Q61K PTPRD 64 273 Age:overall -0.80 -1.69 0.06 1452.87 1.00 724 55 264 9 FALSE 1.10
melanoma NRAS_Q61K RET 28 14 50-65yrs -5.10 -12.21 -0.70 701.98 1.01 311 28 14 0 TRUE 1.05
melanoma NRAS_Q61K RET 25 35 >65yrs -5.14 -12.12 -0.86 768.06 1.00 383 25 35 0 TRUE 1.13
melanoma NRAS_Q61K RET 53 49 Age:overall -5.00 -11.70 -0.82 674.41 1.01 694 53 49 0 TRUE 1.14
melanoma NRAS_Q61K PIK3C2G 27 55 50-65yrs -0.70 -2.03 0.36 1292.95 1.00 262 25 53 2 FALSE 0.61
melanoma NRAS_Q61K PIK3C2G 25 128 >65yrs -0.20 -1.10 0.68 1562.01 1.00 321 18 121 7 FALSE 0.19
melanoma NRAS_Q61K PIK3C2G 52 183 Age:overall -0.46 -2.01 0.98 1341.73 1.00 583 43 174 9 FALSE 0.24
melanoma NRAS_Q61K CREBBP 28 21 50-65yrs -1.04 -2.99 0.47 1088.17 1.00 302 27 20 1 TRUE 0.63
melanoma NRAS_Q61K CREBBP 25 41 >65yrs -1.11 -3.06 0.38 1238.95 1.00 380 24 40 1 TRUE 0.69
melanoma NRAS_Q61K CREBBP 53 62 Age:overall -1.07 -3.04 0.60 1297.61 1.00 682 51 60 2 TRUE 0.59
melanoma NRAS_Q61K DOT1L 28 16 50-65yrs -1.97 -5.48 -0.07 265.61 1.02 304 28 16 0 FALSE 0.79
melanoma NRAS_Q61K DOT1L 25 37 >65yrs -1.62 -4.40 0.18 976.47 1.01 384 24 36 1 FALSE 0.83
melanoma NRAS_Q61K DOT1L 53 53 Age:overall -1.76 -4.59 0.19 387.61 1.02 688 52 52 1 FALSE 0.81
melanoma NRAS_Q61K PTPRS 27 15 50-65yrs -1.55 -4.49 0.58 1374.14 1.00 291 26 14 1 FALSE 0.62
melanoma NRAS_Q61K PTPRS 23 45 >65yrs -2.46 -6.12 -0.26 1424.58 1.00 356 23 45 0 FALSE 0.97
melanoma NRAS_Q61K PTPRS 50 60 Age:overall -1.95 -5.29 0.39 1424.93 1.00 647 49 59 1 FALSE 0.78
melanoma NRAS_Q61K SMARCA4 28 25 50-65yrs -0.62 -2.29 0.63 1327.50 1.00 298 27 24 1 FALSE 0.39
melanoma NRAS_Q61K SMARCA4 25 38 >65yrs -0.49 -1.97 0.71 1291.04 1.00 380 23 36 2 FALSE 0.32
melanoma NRAS_Q61K SMARCA4 53 63 Age:overall -0.56 -2.25 0.76 1333.94 1.00 678 50 60 3 FALSE 0.34
melanoma NRAS_Q61K PTPRT 29 106 50-65yrs 0.53 -0.20 1.21 1461.69 1.00 255 18 95 11 FALSE 0.86
melanoma NRAS_Q61K PTPRT 30 238 >65yrs 0.45 -0.20 1.06 1596.60 1.00 301 14 222 16 FALSE 0.76
melanoma NRAS_Q61K PTPRT 63 364 Age:overall 0.54 -0.26 1.36 1328.60 1.00 625 34 335 29 FALSE 0.70
melanoma NRAS_Q61K HGF 28 22 50-65yrs -0.80 -2.74 0.59 1405.05 1.00 302 27 21 1 FALSE 0.50
melanoma NRAS_Q61K HGF 25 53 >65yrs -0.72 -2.29 0.49 1575.48 1.00 372 23 51 2 FALSE 0.51
melanoma NRAS_Q61K HGF 53 75 Age:overall -0.73 -2.40 0.70 1398.76 1.00 674 50 72 3 FALSE 0.43
melanoma NRAS_Q61K ALK 28 45 50-65yrs -1.96 -6.49 0.13 1103.66 1.00 290 28 45 0 TRUE 0.57
melanoma NRAS_Q61K ALK 26 75 >65yrs 0.09 -1.00 1.15 1338.80 1.00 361 20 69 6 TRUE 0.06
melanoma NRAS_Q61K ALK 54 120 Age:overall -0.88 -3.77 1.16 1426.81 1.00 651 48 114 6 TRUE 0.32
melanoma NRAS_Q61K BAP1 28 24 50-65yrs -0.86 -2.94 0.72 919.70 1.00 298 26 22 2 TRUE 0.47
melanoma NRAS_Q61K BAP1 25 36 >65yrs -1.38 -3.84 0.19 1038.57 1.00 380 25 36 0 TRUE 0.70
melanoma NRAS_Q61K BAP1 53 60 Age:overall -1.09 -3.42 0.59 1162.64 1.00 678 51 58 2 TRUE 0.56
melanoma NRAS_Q61K PTEN 28 27 50-65yrs -0.52 -1.64 0.88 5.46 1.27 299 27 26 1 TRUE 0.32
melanoma NRAS_Q61K PTEN 25 35 >65yrs -0.47 -1.50 0.92 4.51 1.32 384 23 33 2 TRUE 0.28
melanoma NRAS_Q61K PTEN 58 73 Age:overall -0.48 -1.50 0.90 4.50 1.32 761 54 69 4 TRUE 0.29
melanoma NRAS_Q61K CTNNB1 28 17 50-65yrs 0.36 -1.35 1.53 1250.70 1.00 309 27 16 1 TRUE 0.20
melanoma NRAS_Q61K CTNNB1 26 34 >65yrs 1.05 0.07 2.03 1409.36 1.00 389 20 28 6 TRUE 1.47
melanoma NRAS_Q61K CTNNB1 54 51 Age:overall 0.70 -0.85 2.11 1397.11 1.00 698 47 44 7 TRUE 0.45
melanoma NRAS_Q61K ARID1A 29 30 50-65yrs -0.38 -1.73 0.75 1073.80 1.00 294 27 28 2 TRUE 0.26
melanoma NRAS_Q61K ARID1A 25 47 >65yrs -0.42 -1.80 0.65 884.63 1.00 375 23 45 2 TRUE 0.30
melanoma NRAS_Q61K ARID1A 54 77 Age:overall -0.37 -1.76 0.92 989.96 1.00 669 50 73 4 TRUE 0.22
melanoma NRAS_Q61K IKZF1 28 36 50-65yrs -0.74 -2.23 0.40 1007.23 1.00 290 27 35 1 TRUE 0.57
melanoma NRAS_Q61K IKZF1 25 56 >65yrs -0.50 -1.75 0.64 1026.33 1.00 377 22 53 3 TRUE 0.38
melanoma NRAS_Q61K IKZF1 53 92 Age:overall -0.60 -2.03 0.62 1253.24 1.00 667 49 88 4 TRUE 0.42
melanoma NRAS_Q61K TERT 6 39 <40yrs 1.15 0.46 1.94 812.41 1.00 41 1 34 5 TRUE 2.48
melanoma NRAS_Q61K TERT 30 208 50-65yrs 1.12 0.51 1.82 607.95 1.00 162 8 186 22 TRUE 3.06
melanoma NRAS_Q61K TERT 27 312 >65yrs 1.05 0.42 1.75 986.10 1.00 192 5 290 22 TRUE 2.71
melanoma NRAS_Q61K TERT 67 614 Age:overall 1.12 0.49 1.82 844.87 1.00 436 14 561 53 TRUE 2.91
melanoma NRAS_Q61K FAT1 28 45 50-65yrs -0.18 -1.29 0.69 296.23 1.01 285 25 42 3 FALSE 0.13
melanoma NRAS_Q61K FAT1 25 92 >65yrs -0.12 -1.10 0.72 292.81 1.01 351 20 87 5 FALSE 0.09
melanoma NRAS_Q61K FAT1 53 137 Age:overall -0.17 -1.46 0.89 355.40 1.01 636 45 129 8 FALSE 0.11
melanoma NRAS_Q61K CIC 28 18 50-65yrs -0.34 -2.09 0.93 916.11 1.00 304 27 17 1 TRUE 0.19
melanoma NRAS_Q61K CIC 25 32 >65yrs -0.21 -1.79 1.02 758.79 1.00 387 23 30 2 TRUE 0.11
melanoma NRAS_Q61K CIC 53 50 Age:overall -0.28 -2.08 1.03 786.58 1.00 691 50 47 3 TRUE 0.13
melanoma NRAS_Q61K KDM6A 6 43 <40yrs -2.29 -5.60 -0.13 1508.14 1.00 70 6 43 0 FALSE 0.95
melanoma NRAS_Q61K KDM6A 28 13 50-65yrs -0.82 -3.32 1.06 1601.31 1.00 309 27 12 1 FALSE 0.33
melanoma NRAS_Q61K KDM6A 25 15 >65yrs -0.72 -3.44 1.28 1521.03 1.00 401 24 14 1 FALSE 0.27
melanoma NRAS_Q61K KDM6A 59 71 Age:overall -1.23 -3.81 1.09 1573.81 1.00 780 57 69 2 FALSE 0.49
melanoma NRAS_Q61K POLE 29 21 50-65yrs 0.82 -0.44 1.98 729.10 1.00 304 24 16 5 TRUE 0.75
melanoma NRAS_Q61K POLE 25 43 >65yrs -0.38 -2.36 0.88 1136.69 1.00 374 24 42 1 TRUE 0.19
melanoma NRAS_Q61K POLE 54 64 Age:overall 0.22 -1.88 2.04 1468.21 1.00 678 48 58 6 TRUE 0.09
melanoma NRAS_Q61K NOTCH2 27 18 50-65yrs -0.27 -2.01 1.04 1310.72 1.00 288 26 17 1 TRUE 0.14
melanoma NRAS_Q61K NOTCH2 23 41 >65yrs 0.02 -1.33 1.13 1293.93 1.00 365 20 38 3 TRUE 0.01
melanoma NRAS_Q61K NOTCH2 50 59 Age:overall -0.13 -1.98 1.26 1282.05 1.00 653 46 55 4 TRUE 0.06
melanoma NRAS_Q61K KMT2A 28 37 50-65yrs -0.88 -2.50 0.33 1472.44 1.00 292 27 36 1 FALSE 0.63
melanoma NRAS_Q61K KMT2A 26 90 >65yrs -0.29 -1.33 0.69 1460.14 1.00 357 21 85 5 FALSE 0.23
melanoma NRAS_Q61K KMT2A 54 127 Age:overall -0.56 -2.25 0.92 1378.60 1.00 649 48 121 6 FALSE 0.32
melanoma NRAS_Q61K PAK7 27 65 50-65yrs -0.89 -2.27 0.11 1539.66 1.00 255 26 64 1 FALSE 0.84
melanoma NRAS_Q61K PAK7 25 131 >65yrs -0.35 -1.24 0.51 1439.69 1.00 311 18 124 7 FALSE 0.37
melanoma NRAS_Q61K PAK7 56 211 Age:overall -0.58 -1.76 0.42 1715.57 1.00 634 47 202 9 FALSE 0.54
melanoma NRAS_Q61K BRCA2 28 22 50-65yrs 0.05 -1.70 1.51 669.13 1.00 303 25 19 3 TRUE 0.02
melanoma NRAS_Q61K BRCA2 25 63 >65yrs -2.31 -7.30 -0.03 973.93 1.00 368 25 63 0 TRUE 0.64
melanoma NRAS_Q61K BRCA2 53 85 Age:overall -1.01 -4.41 1.42 1373.19 1.00 671 50 82 3 TRUE 0.32
melanoma NRAS_Q61K NOTCH3 28 32 50-65yrs -1.92 -6.87 0.38 869.03 1.01 292 28 32 0 TRUE 0.50
melanoma NRAS_Q61K NOTCH3 26 87 >65yrs 0.50 -0.38 1.39 1408.83 1.00 359 18 79 8 TRUE 0.55
melanoma NRAS_Q61K NOTCH3 54 119 Age:overall -0.66 -4.20 1.47 1186.69 1.00 651 46 111 8 TRUE 0.19
melanoma NRAS_Q61K NOTCH4 28 48 50-65yrs -0.38 -1.49 0.57 1256.25 1.00 268 25 45 3 TRUE 0.35
melanoma NRAS_Q61K NOTCH4 23 92 >65yrs -0.36 -1.38 0.53 1375.93 1.00 334 19 88 4 TRUE 0.35
melanoma NRAS_Q61K NOTCH4 51 140 Age:overall -0.37 -1.54 0.76 1126.28 1.00 602 44 133 7 TRUE 0.25
melanoma NRAS_Q61K CDKN2A 7 12 <40yrs 0.22 -0.63 1.06 915.30 1.00 67 5 10 2 TRUE 0.21
melanoma NRAS_Q61K CDKN2A 28 43 50-65yrs 0.08 -0.86 0.84 892.07 1.00 288 26 41 2 TRUE 0.07
melanoma NRAS_Q61K CDKN2A 27 65 >65yrs 0.22 -0.59 0.97 757.51 1.00 363 21 59 6 TRUE 0.23
melanoma NRAS_Q61K CDKN2A 62 120 Age:overall 0.18 -0.63 0.94 812.71 1.00 718 52 110 10 TRUE 0.18
melanoma NRAS_Q61K EPHB1 28 19 50-65yrs -0.92 -2.89 0.57 1281.09 1.00 303 27 18 1 FALSE 0.53
melanoma NRAS_Q61K EPHB1 25 39 >65yrs -1.00 -2.97 0.42 1267.24 1.00 381 24 38 1 FALSE 0.62
melanoma NRAS_Q61K EPHB1 53 58 Age:overall -0.96 -2.87 0.66 1206.73 1.00 684 51 56 2 FALSE 0.55
melanoma NRAS_Q61K IL7R 28 34 50-65yrs -1.14 -2.91 0.29 1159.65 1.00 294 26 32 2 FALSE 0.77
melanoma NRAS_Q61K IL7R 25 51 >65yrs -1.73 -4.59 -0.13 969.26 1.00 375 25 51 0 FALSE 0.87
melanoma NRAS_Q61K IL7R 53 85 Age:overall -1.43 -3.53 0.15 1227.75 1.00 669 51 83 2 FALSE 0.85
melanoma NRAS_Q61K ATM 28 22 50-65yrs -0.66 -2.28 0.59 1238.62 1.00 306 27 21 1 TRUE 0.44
melanoma NRAS_Q61K ATM 25 47 >65yrs -0.59 -2.02 0.61 1264.63 1.00 374 23 45 2 TRUE 0.41
melanoma NRAS_Q61K ATM 53 69 Age:overall -0.61 -2.27 0.74 1077.10 1.00 680 50 66 3 TRUE 0.37
melanoma NRAS_Q61K MAP2K1 28 17 50-65yrs -0.40 -2.12 0.94 1251.33 1.00 304 27 16 1 TRUE 0.22
melanoma NRAS_Q61K MAP2K1 25 36 >65yrs -0.30 -1.87 0.94 1080.75 1.00 382 23 34 2 TRUE 0.17
melanoma NRAS_Q61K MAP2K1 53 53 Age:overall -0.34 -2.12 1.05 990.13 1.00 686 50 50 3 TRUE 0.17
melanoma NRAS_Q61K RB1 28 15 50-65yrs 0.64 -0.65 1.71 1249.29 1.00 313 26 13 2 TRUE 0.54
melanoma NRAS_Q61K RB1 25 24 >65yrs 0.71 -0.45 1.76 1238.26 1.00 398 22 21 3 TRUE 0.65
melanoma NRAS_Q61K RB1 53 39 Age:overall 0.68 -0.78 1.93 977.75 1.00 711 48 34 5 TRUE 0.49
melanoma NRAS_Q61K KMT2D 29 63 50-65yrs -0.01 -0.86 0.78 1435.29 1.00 278 24 58 5 FALSE 0.01
melanoma NRAS_Q61K KMT2D 26 140 >65yrs 0.04 -0.75 0.79 1517.00 1.00 338 18 132 8 FALSE 0.04
melanoma NRAS_Q61K KMT2D 55 203 Age:overall 0.02 -1.18 1.21 1355.88 1.00 616 42 190 13 FALSE 0.01
melanoma NRAS_Q61K APC 28 58 50-65yrs 0.05 -0.88 0.91 1096.34 1.00 291 23 53 5 TRUE 0.04
melanoma NRAS_Q61K APC 25 60 >65yrs -0.05 -1.06 0.83 1120.53 1.00 372 22 57 3 TRUE 0.04
melanoma NRAS_Q61K APC 53 118 Age:overall -0.01 -1.12 1.03 1314.26 1.00 663 45 110 8 TRUE 0.00
melanoma NRAS_Q61K ARID2 6 20 <40yrs 0.15 -1.56 1.24 1384.13 1.00 69 6 20 0 FALSE 0.07
melanoma NRAS_Q61K ARID2 29 42 50-65yrs 0.74 -0.01 1.60 1510.87 1.00 295 21 34 8 FALSE 1.13
melanoma NRAS_Q61K ARID2 26 79 >65yrs 0.40 -0.38 1.10 1449.63 1.00 361 20 73 6 FALSE 0.52
melanoma NRAS_Q61K ARID2 61 141 Age:overall 0.42 -0.63 1.27 1424.88 1.00 725 47 127 14 FALSE 0.42
melanoma NRAS_Q61K MTOR 28 21 50-65yrs -1.57 -4.45 0.24 230.92 1.02 300 27 20 1 TRUE 0.74
melanoma NRAS_Q61K MTOR 25 26 >65yrs -1.82 -5.24 0.12 233.04 1.02 393 25 26 0 TRUE 0.71
melanoma NRAS_Q61K MTOR 53 47 Age:overall -1.67 -4.76 0.22 245.93 1.02 693 52 46 1 TRUE 0.73
melanoma NRAS_Q61K NOTCH1 28 15 50-65yrs -0.42 -2.21 0.99 1139.00 1.00 311 27 14 1 TRUE 0.21
melanoma NRAS_Q61K NOTCH1 25 43 >65yrs -0.40 -1.97 0.87 1382.96 1.00 382 23 41 2 TRUE 0.23
melanoma NRAS_Q61K NOTCH1 53 58 Age:overall -0.41 -2.33 1.22 1357.14 1.00 693 50 55 3 TRUE 0.19
melanoma NRAS_Q61K NTRK1 28 13 50-65yrs -2.00 -5.79 0.26 1260.67 1.00 310 28 13 0 TRUE 0.71
melanoma NRAS_Q61K NTRK1 25 35 >65yrs -1.58 -4.30 0.36 1360.19 1.00 383 24 34 1 TRUE 0.73
melanoma NRAS_Q61K NTRK1 53 48 Age:overall -1.72 -4.97 0.55 1408.82 1.00 693 52 47 1 TRUE 0.70
melanoma NRAS_Q61K SETD2 28 28 50-65yrs -1.48 -4.73 0.14 796.68 1.00 297 28 28 0 FALSE 0.57
melanoma NRAS_Q61K SETD2 25 54 >65yrs -0.57 -2.15 0.68 766.11 1.00 375 22 51 3 FALSE 0.37
melanoma NRAS_Q61K SETD2 53 82 Age:overall -1.00 -3.37 0.65 894.34 1.00 672 50 79 3 FALSE 0.46
melanoma NRAS_Q61K PBRM1 28 23 50-65yrs 0.02 -1.26 1.18 911.34 1.00 303 25 20 3 TRUE 0.01
melanoma NRAS_Q61K PBRM1 25 42 >65yrs -0.45 -2.05 0.74 1191.34 1.00 380 24 41 1 TRUE 0.28
melanoma NRAS_Q61K PBRM1 53 65 Age:overall -0.18 -1.74 1.20 1167.32 1.00 683 49 61 4 TRUE 0.09
melanoma NRAS_Q61K EPHA3 28 32 50-65yrs 0.23 -0.86 1.13 1131.16 1.00 297 25 29 3 FALSE 0.18
melanoma NRAS_Q61K EPHA3 25 67 >65yrs 0.31 -0.63 1.15 1202.03 1.00 369 20 62 5 FALSE 0.29
melanoma NRAS_Q61K EPHA3 53 99 Age:overall 0.27 -1.09 1.55 1031.32 1.00 666 45 91 8 FALSE 0.17
melanoma NRAS_Q61K KIT 28 22 50-65yrs -2.28 -5.54 -0.23 558.24 1.00 305 28 22 0 TRUE 1.05
melanoma NRAS_Q61K KIT 25 40 >65yrs -1.98 -5.04 -0.01 285.27 1.01 381 24 39 1 TRUE 1.00
melanoma NRAS_Q61K KIT 53 62 Age:overall -2.11 -5.26 -0.10 369.39 1.01 686 52 61 1 TRUE 1.02
melanoma NRAS_Q61K KDR 28 38 50-65yrs -1.74 -3.69 -0.32 859.81 1.00 295 27 37 1 TRUE 1.27
melanoma NRAS_Q61K KDR 25 80 >65yrs -1.83 -3.80 -0.36 945.05 1.00 356 24 79 1 TRUE 1.42
melanoma NRAS_Q61K KDR 53 118 Age:overall -1.77 -3.88 -0.11 991.32 1.00 651 51 116 2 TRUE 1.13
melanoma NRAS_Q61K CSF1R 28 20 50-65yrs 0.05 -1.21 1.16 1590.94 1.00 307 26 18 2 TRUE 0.03
melanoma NRAS_Q61K CSF1R 25 34 >65yrs -0.02 -1.34 1.08 1476.52 1.00 392 23 32 2 TRUE 0.01
melanoma NRAS_Q61K CSF1R 53 54 Age:overall 0.01 -1.36 1.31 1513.28 1.00 699 49 50 4 TRUE 0.01
melanoma NRAS_Q61K PTCH1 28 15 50-65yrs -4.98 -11.86 -0.40 697.50 1.00 306 28 15 0 TRUE 1.07
melanoma NRAS_Q61K PTCH1 25 35 >65yrs -5.01 -12.05 -0.53 664.32 1.00 382 25 35 0 TRUE 1.08
melanoma NRAS_Q61K PTCH1 53 50 Age:overall -4.87 -11.69 -0.26 701.93 1.00 688 53 50 0 TRUE 1.05
melanoma NRAS_Q61K TET1 27 17 50-65yrs -0.12 -1.63 1.08 1325.54 1.00 291 26 16 1 FALSE 0.06
melanoma NRAS_Q61K TET1 23 36 >65yrs 0.15 -1.10 1.24 1561.87 1.00 369 20 33 3 FALSE 0.10
melanoma NRAS_Q61K TET1 50 53 Age:overall 0.02 -1.42 1.40 1261.83 1.00 660 46 49 4 FALSE 0.01
melanoma NRAS_Q61K FGFR2 28 23 50-65yrs -1.77 -5.12 0.06 1285.37 1.00 306 28 23 0 TRUE 0.74
melanoma NRAS_Q61K FGFR2 25 53 >65yrs -1.07 -2.89 0.38 1317.07 1.00 378 23 51 2 TRUE 0.69
melanoma NRAS_Q61K FGFR2 53 76 Age:overall -1.38 -3.82 0.40 1240.84 1.00 684 51 74 2 TRUE 0.68
melanoma NRAS_Q61K TBX3 28 15 50-65yrs -1.01 -5.11 0.83 1276.97 1.00 306 28 15 0 FALSE 0.27
melanoma NRAS_Q61K TBX3 26 40 >65yrs 0.26 -1.05 1.37 1057.44 1.00 386 22 36 4 FALSE 0.17
melanoma NRAS_Q61K TBX3 54 55 Age:overall -0.33 -3.22 1.43 1291.79 1.00 692 50 51 4 FALSE 0.11
melanoma NRAS_Q61K DICER1 25 39 >65yrs -1.36 -4.28 0.55 1366.53 1.00 381 24 38 1 TRUE 0.55
melanoma NRAS_Q61K DICER1 25 39 Age:overall -1.14 -6.47 3.71 1601.76 1.00 381 24 38 1 TRUE 0.20
melanoma NRAS_Q61K NTRK3 28 29 50-65yrs -1.05 -2.94 0.38 1152.18 1.00 294 27 28 1 FALSE 0.71
melanoma NRAS_Q61K NTRK3 25 68 >65yrs -0.96 -2.42 0.25 1164.62 1.00 367 23 66 2 FALSE 0.77
melanoma NRAS_Q61K NTRK3 53 97 Age:overall -1.00 -2.89 0.59 1460.53 1.00 661 50 94 3 FALSE 0.60
melanoma NRAS_Q61K GRIN2A 28 93 50-65yrs -0.57 -1.52 0.29 1225.65 1.00 262 23 88 5 FALSE 0.65
melanoma NRAS_Q61K GRIN2A 28 192 >65yrs -0.63 -1.45 0.16 1563.11 1.00 307 21 185 7 FALSE 0.93
melanoma NRAS_Q61K GRIN2A 60 297 Age:overall -0.69 -1.86 0.44 1361.57 1.00 646 48 285 12 FALSE 0.62
melanoma NRAS_Q61K BRD4 28 16 50-65yrs 0.55 -0.73 1.70 1010.36 1.00 308 25 13 3 FALSE 0.42
melanoma NRAS_Q61K BRD4 25 36 >65yrs 0.17 -1.18 1.30 662.99 1.01 386 23 34 2 FALSE 0.10
melanoma NRAS_Q61K BRD4 53 52 Age:overall 0.38 -1.14 1.78 972.30 1.00 694 48 47 5 FALSE 0.21
melanoma NRAS_Q61K ASXL1 28 14 50-65yrs -0.82 -4.66 1.14 1249.84 1.00 307 28 14 0 TRUE 0.22
melanoma NRAS_Q61K ASXL1 25 32 >65yrs 0.53 -0.86 1.69 1124.17 1.00 388 21 28 4 TRUE 0.39
melanoma NRAS_Q61K ASXL1 53 46 Age:overall -0.15 -2.93 1.79 1328.57 1.00 695 49 42 4 TRUE 0.05
melanoma NRAS_Q61K EP300 28 15 50-65yrs -4.44 -10.79 -0.80 20.64 1.18 305 28 15 0 TRUE 0.92
melanoma NRAS_Q61K EP300 25 37 >65yrs -4.42 -10.88 -0.81 20.14 1.18 382 25 37 0 TRUE 0.90
melanoma NRAS_Q61K EP300 53 52 Age:overall -4.33 -10.35 -0.86 20.10 1.18 687 53 52 0 TRUE 0.91
melanoma NRAS_Q61K ERBB4 28 63 50-65yrs -1.30 -2.53 -0.25 1447.14 1.00 281 26 61 2 TRUE 1.54
melanoma NRAS_Q61K ERBB4 25 114 >65yrs -1.48 -2.83 -0.41 1221.02 1.00 338 24 113 1 TRUE 1.77
melanoma NRAS_Q61K ERBB4 58 189 Age:overall -1.32 -2.65 -0.17 1259.31 1.00 698 54 185 4 TRUE 1.47
melanoma NRAS_Q61K MDC1 27 19 50-65yrs -0.55 -2.37 0.86 1500.79 1.00 288 26 18 1 FALSE 0.30
melanoma NRAS_Q61K MDC1 23 60 >65yrs -0.33 -1.64 0.76 1493.38 1.00 351 20 57 3 FALSE 0.22
melanoma NRAS_Q61K MDC1 50 79 Age:overall -0.45 -2.29 1.24 1232.56 1.00 639 46 75 4 FALSE 0.21
melanoma NRAS_Q61K GNAQ 28 19 50-65yrs -1.14 -3.98 0.54 440.02 1.00 307 28 19 0 TRUE 0.44
melanoma NRAS_Q61K GNAQ 25 31 >65yrs -0.58 -2.58 0.81 535.77 1.00 387 23 29 2 TRUE 0.29
melanoma NRAS_Q61K GNAQ 53 50 Age:overall -0.82 -3.18 0.80 528.07 1.00 694 51 48 2 TRUE 0.37
melanoma NRAS_Q61K MED12 28 19 50-65yrs -0.77 -2.73 0.70 1197.44 1.00 307 27 18 1 TRUE 0.43
melanoma NRAS_Q61K MED12 25 31 >65yrs -0.80 -2.64 0.68 1169.14 1.00 390 24 30 1 TRUE 0.48
melanoma NRAS_Q61K MED12 53 50 Age:overall -0.79 -2.68 0.76 1236.57 1.00 697 51 48 2 TRUE 0.43
melanoma NRAS_Q61K NF1 28 93 50-65yrs -3.12 -5.75 -1.43 1435.73 1.00 258 28 93 0 TRUE 2.34
melanoma NRAS_Q61K NF1 25 183 >65yrs -2.59 -4.50 -1.22 1391.60 1.00 295 23 181 2 TRUE 2.62
melanoma NRAS_Q61K NF1 57 290 Age:overall -2.83 -4.99 -1.15 1415.55 1.00 625 55 288 2 TRUE 2.43
melanoma NRAS_Q61K FLT1 28 34 50-65yrs -1.24 -2.99 0.07 1374.03 1.00 291 27 33 1 FALSE 0.94
melanoma NRAS_Q61K FLT1 25 80 >65yrs -1.14 -2.61 0.06 1405.91 1.00 358 23 78 2 FALSE 1.04
melanoma NRAS_Q61K FLT1 53 114 Age:overall -1.17 -2.90 0.26 1307.91 1.00 649 50 111 3 FALSE 0.83
melanoma NRAS_Q61K RPTOR 28 17 50-65yrs 0.19 -1.17 1.40 677.08 1.00 306 26 15 2 FALSE 0.11
melanoma NRAS_Q61K RPTOR 25 29 >65yrs 0.13 -1.18 1.31 633.72 1.00 387 23 27 2 FALSE 0.07
melanoma NRAS_Q61K RPTOR 53 46 Age:overall 0.15 -1.37 1.52 856.96 1.00 693 49 42 4 FALSE 0.08
melanoma NRAS_Q61K SF3B1 28 43 50-65yrs -2.13 -4.86 -0.38 473.17 1.00 278 27 42 1 TRUE 1.17
melanoma NRAS_Q61K SF3B1 25 36 >65yrs -2.47 -5.91 -0.49 516.31 1.00 378 25 36 0 TRUE 1.07
melanoma NRAS_Q61K SF3B1 53 79 Age:overall -2.27 -5.23 -0.24 506.67 1.00 656 52 78 1 TRUE 1.07
melanoma NRAS_Q61K ROS1 28 71 50-65yrs -1.66 -3.18 -0.50 1387.91 1.00 272 27 70 1 TRUE 1.76
melanoma NRAS_Q61K ROS1 25 163 >65yrs -1.30 -2.42 -0.29 1507.58 1.00 318 21 159 4 TRUE 1.81
melanoma NRAS_Q61K ROS1 57 248 Age:overall -1.51 -2.86 -0.28 1424.40 1.00 663 52 243 5 TRUE 1.62
melanoma NRAS_Q61K FLT3 28 28 50-65yrs 0.17 -0.88 1.25 1441.05 1.00 302 24 24 4 TRUE 0.12
melanoma NRAS_Q61K FLT3 25 46 >65yrs -0.40 -2.08 0.73 1229.40 1.00 377 24 45 1 TRUE 0.24
melanoma NRAS_Q61K FLT3 53 74 Age:overall -0.11 -1.62 1.17 1450.58 1.00 679 48 69 5 TRUE 0.06
melanoma NRAS_Q61K AXL 29 15 50-65yrs 1.02 -0.27 2.27 1494.95 1.00 309 25 11 4 FALSE 0.97
melanoma NRAS_Q61K AXL 25 42 >65yrs 0.07 -1.40 1.23 1519.72 1.00 380 23 40 2 FALSE 0.04
melanoma NRAS_Q61K AXL 54 57 Age:overall 0.54 -1.21 2.29 1516.92 1.00 689 48 51 6 FALSE 0.27
melanoma NRAS_Q61K PIK3CG 28 28 50-65yrs -1.45 -3.66 0.11 1319.68 1.00 295 27 27 1 FALSE 0.90
melanoma NRAS_Q61K PIK3CG 25 73 >65yrs -1.63 -3.54 -0.24 1457.21 1.00 367 24 72 1 FALSE 1.25
melanoma NRAS_Q61K PIK3CG 53 101 Age:overall -1.52 -3.68 0.32 1548.68 1.00 662 51 99 2 FALSE 0.93
melanoma NRAS_Q61K EGFR 28 21 50-65yrs -1.08 -5.20 0.74 1278.87 1.00 305 28 21 0 TRUE 0.32
melanoma NRAS_Q61K EGFR 25 39 >65yrs 0.25 -1.06 1.45 1101.45 1.01 387 21 35 4 TRUE 0.16
melanoma NRAS_Q61K EGFR 53 60 Age:overall -0.38 -3.10 1.45 1542.13 1.00 692 49 56 4 TRUE 0.13
melanoma NRAS_Q61K ARID1B 6 13 <40yrs -1.94 -4.89 0.17 415.41 1.01 69 5 12 1 TRUE 0.98
melanoma NRAS_Q61K ARID1B 28 23 50-65yrs -2.19 -5.39 -0.35 478.27 1.00 302 28 23 0 TRUE 1.15
melanoma NRAS_Q61K ARID1B 25 35 >65yrs -2.17 -5.25 -0.35 494.87 1.00 381 25 35 0 TRUE 1.20
melanoma NRAS_Q61K ARID1B 59 71 Age:overall -2.09 -5.06 -0.29 471.71 1.00 752 58 70 1 TRUE 1.18
melanoma NRAS_Q61K GNA11 28 23 50-65yrs -4.88 -11.26 -0.62 181.24 1.02 302 28 23 0 TRUE 1.03
melanoma NRAS_Q61K GNA11 25 22 >65yrs -4.92 -11.36 -0.57 159.99 1.02 395 25 22 0 TRUE 1.03
melanoma NRAS_Q61K GNA11 53 45 Age:overall -4.82 -11.09 -0.58 170.28 1.02 697 53 45 0 TRUE 1.05
melanoma NRAS_Q61K INSR 27 16 50-65yrs -0.52 -2.23 0.91 1479.75 1.00 289 26 15 1 FALSE 0.28
melanoma NRAS_Q61K INSR 23 47 >65yrs -0.46 -1.97 0.81 1372.35 1.00 365 21 45 2 FALSE 0.28
melanoma NRAS_Q61K INSR 50 63 Age:overall -0.53 -2.49 1.19 1385.77 1.00 654 47 60 3 FALSE 0.25
melanoma NRAS_Q61K ERG 28 18 50-65yrs -0.16 -1.73 1.17 1341.72 1.00 305 26 16 2 FALSE 0.08
melanoma NRAS_Q61K ERG 25 30 >65yrs -0.37 -2.14 0.89 1588.65 1.00 391 24 29 1 FALSE 0.20
melanoma NRAS_Q61K ERG 53 48 Age:overall -0.26 -2.06 1.16 1563.29 1.00 696 50 45 3 FALSE 0.13
melanoma NRAS_Q61K MET 28 26 50-65yrs -0.36 -2.06 0.80 897.57 1.00 302 27 25 1 TRUE 0.21
melanoma NRAS_Q61K MET 25 52 >65yrs 0.04 -1.13 1.09 1295.63 1.00 372 21 48 4 TRUE 0.03
melanoma NRAS_Q61K MET 53 78 Age:overall -0.16 -1.60 1.07 1075.44 1.00 674 48 73 5 TRUE 0.08
melanoma NRAS_Q61K BRAF 7 28 <40yrs -1.21 -2.48 -0.15 1456.59 1.00 48 6 27 1 TRUE 1.43
melanoma NRAS_Q61K BRAF 28 120 50-65yrs -1.72 -3.40 -0.68 1347.46 1.00 213 28 120 0 TRUE 1.86
melanoma NRAS_Q61K BRAF 28 115 >65yrs -0.78 -1.76 0.21 1368.08 1.00 317 21 108 7 TRUE 0.94
melanoma NRAS_Q61K BRAF 68 299 Age:overall -1.23 -2.24 -0.41 1511.82 1.00 632 59 290 9 TRUE 2.01
melanoma NRAS_Q61K TET2 28 35 50-65yrs -1.18 -2.97 0.28 1276.00 1.00 293 26 33 2 TRUE 0.82
melanoma NRAS_Q61K TET2 25 48 >65yrs -1.70 -4.27 -0.14 893.63 1.00 375 25 48 0 TRUE 0.90
melanoma NRAS_Q61K TET2 53 83 Age:overall -1.42 -3.69 0.23 1126.20 1.00 668 51 81 2 TRUE 0.84
melanoma NRAS_Q61K PDGFRB 28 16 50-65yrs -1.54 -4.43 0.58 1248.67 1.00 306 27 15 1 TRUE 0.65
melanoma NRAS_Q61K PDGFRB 25 47 >65yrs -2.41 -6.16 -0.20 1086.36 1.00 382 25 47 0 TRUE 0.90
melanoma NRAS_Q61K PDGFRB 53 63 Age:overall -1.91 -4.92 0.51 1202.46 1.00 688 52 62 1 TRUE 0.77
melanoma NRAS_Q61K CARD11 28 29 50-65yrs -1.74 -6.39 0.10 1275.59 1.00 294 28 29 0 FALSE 0.52
melanoma NRAS_Q61K CARD11 26 75 >65yrs -0.13 -1.34 0.91 1593.37 1.00 361 21 70 5 FALSE 0.09
melanoma NRAS_Q61K CARD11 54 104 Age:overall -0.85 -3.45 1.25 1481.53 1.00 655 49 99 5 FALSE 0.33
melanoma NRAS_Q61K CBL 28 25 50-65yrs -2.50 -5.94 -0.35 1145.21 1.00 296 28 25 0 TRUE 1.04
melanoma NRAS_Q61K CBL 25 52 >65yrs -2.12 -4.94 -0.23 1128.62 1.00 370 24 51 1 TRUE 1.07
melanoma NRAS_Q61K CBL 53 77 Age:overall -2.27 -5.49 -0.11 1322.71 1.00 666 52 76 1 TRUE 0.99
melanoma NRAS_Q61K TP63 29 59 50-65yrs 0.29 -0.46 1.14 508.93 1.02 264 21 51 8 FALSE 0.31
melanoma NRAS_Q61K TP63 23 91 >65yrs -0.28 -1.42 0.55 848.32 1.00 328 21 89 2 FALSE 0.24
melanoma NRAS_Q61K TP63 56 161 Age:overall 0.04 -0.82 1.00 1394.02 1.00 665 45 150 11 FALSE 0.03
melanoma NRAS_Q61K GLI1 26 18 50-65yrs -0.51 -2.27 0.90 1424.52 1.00 287 25 17 1 FALSE 0.28
melanoma NRAS_Q61K GLI1 24 40 >65yrs -0.42 -1.91 0.82 1377.44 1.00 359 22 38 2 FALSE 0.26
melanoma NRAS_Q61K GLI1 50 58 Age:overall -0.45 -2.24 1.08 1443.62 1.00 646 47 55 3 FALSE 0.23
melanoma NRAS_Q61K ZFHX3 6 42 <40yrs -2.62 -5.78 -0.70 1499.12 1.00 64 6 42 0 FALSE 1.26
melanoma NRAS_Q61K ZFHX3 26 32 50-65yrs -1.33 -3.19 0.25 1457.51 1.00 275 24 30 2 FALSE 0.85
melanoma NRAS_Q61K ZFHX3 24 65 >65yrs -2.69 -5.74 -0.73 1414.87 1.00 340 24 65 0 FALSE 1.36
melanoma NRAS_Q61K ZFHX3 56 139 Age:overall -2.16 -4.59 -0.26 1490.12 1.00 679 54 137 2 FALSE 1.31
melanoma NRAS_Q61K MGA 26 38 50-65yrs -0.16 -1.27 0.88 184.32 1.01 276 22 34 4 FALSE 0.10
melanoma NRAS_Q61K MGA 24 50 >65yrs -0.50 -1.96 0.56 456.79 1.01 350 23 49 1 FALSE 0.35
melanoma NRAS_Q61K MGA 50 88 Age:overall -0.32 -1.71 0.82 337.02 1.01 626 45 83 5 FALSE 0.20
melanoma NRAS_Q61K ANKRD11 25 25 50-65yrs -1.61 -4.49 0.10 1203.27 1.00 265 25 25 0 FALSE 0.76
melanoma NRAS_Q61K ANKRD11 22 44 >65yrs -1.06 -2.79 0.54 756.68 1.00 340 20 42 2 FALSE 0.70
melanoma NRAS_Q61K ANKRD11 47 69 Age:overall -1.32 -3.59 0.50 1235.74 1.00 605 45 67 2 FALSE 0.72
melanoma NRAS_Q61K PGR 25 19 50-65yrs -1.95 -5.58 0.05 679.21 1.00 270 25 19 0 FALSE 0.76
melanoma NRAS_Q61K PGR 22 33 >65yrs -1.63 -4.55 0.30 926.61 1.00 341 21 32 1 FALSE 0.74
melanoma NRAS_Q61K PGR 47 52 Age:overall -1.76 -5.00 0.24 928.36 1.00 611 46 51 1 FALSE 0.74
melanoma NRAS_Q61K PLCG2 25 17 50-65yrs -2.19 -5.76 0.05 1290.43 1.00 274 25 17 0 FALSE 0.84
melanoma NRAS_Q61K PLCG2 22 41 >65yrs -1.77 -4.65 0.16 1356.46 1.00 333 21 40 1 FALSE 0.85
melanoma NRAS_Q61K PLCG2 47 58 Age:overall -1.98 -5.10 0.30 1329.03 1.00 607 46 57 1 FALSE 0.80
melanoma NRAS_Q61K EPHA7 26 38 50-65yrs -0.08 -1.24 0.91 1495.65 1.00 274 23 35 3 FALSE 0.05
melanoma NRAS_Q61K EPHA7 25 105 >65yrs -0.06 -0.98 0.78 1450.18 1.00 319 19 99 6 FALSE 0.05
melanoma NRAS_Q61K EPHA7 51 143 Age:overall -0.06 -1.47 1.37 1462.51 1.00 593 42 134 9 FALSE 0.03
melanoma NRAS_Q61R SPEN 27 35 50-65yrs -0.32 -1.43 0.80 1397.08 1.00 297 24 32 3 FALSE 0.24
melanoma NRAS_Q61R SPEN 38 70 >65yrs -0.62 -1.79 0.33 1434.43 1.00 358 35 67 3 FALSE 0.61
melanoma NRAS_Q61R SPEN 65 105 Age:overall -0.48 -1.85 0.70 1722.48 1.00 655 59 99 6 FALSE 0.34
melanoma NRAS_Q61R KMT2C 27 55 50-65yrs 0.43 -0.58 1.35 1198.68 1.00 266 19 47 8 FALSE 0.40
melanoma NRAS_Q61R KMT2C 36 79 >65yrs -0.87 -2.42 0.21 1393.91 1.00 325 34 77 2 FALSE 0.67
melanoma NRAS_Q61R KMT2C 63 134 Age:overall -0.18 -1.75 1.43 1532.00 1.00 591 53 124 10 FALSE 0.08
melanoma NRAS_Q61R TP53 13 20 40-50yrs -0.58 -1.51 0.20 1442.63 1.00 61 12 19 1 TRUE 0.73
melanoma NRAS_Q61R TP53 27 72 50-65yrs -0.37 -1.09 0.46 740.54 1.00 269 20 65 7 TRUE 0.46
melanoma NRAS_Q61R TP53 38 105 >65yrs -0.62 -1.35 0.05 1153.81 1.00 322 34 101 4 TRUE 1.06
thyroid cancer NRAS_Q61R TP53 25 36 50-65yrs 0.26 -0.50 1.01 1277.65 1.00 134 20 31 5 TRUE 0.31
thyroid cancer NRAS_Q61R TP53 31 34 >65yrs 0.34 -0.43 1.10 1404.02 1.00 155 24 27 7 TRUE 0.41
melanoma NRAS_Q61R TP53 82 210 Age:overall -0.53 -1.27 0.14 926.22 1.00 717 70 198 12 TRUE 0.86
thyroid cancer NRAS_Q61R TP53 56 70 Age:overall 0.30 -0.66 1.14 1430.29 1.00 289 44 58 12 TRUE 0.29
melanoma NRAS_Q61R ATRX 13 13 40-50yrs -0.62 -1.70 0.42 104.00 1.02 68 12 12 1 TRUE 0.56
melanoma NRAS_Q61R ATRX 28 40 50-65yrs -0.58 -1.62 0.39 73.29 1.03 295 25 37 3 TRUE 0.54
melanoma NRAS_Q61R ATRX 38 43 >65yrs -0.66 -1.67 0.22 78.63 1.03 364 36 41 2 TRUE 0.70
melanoma NRAS_Q61R ATRX 82 108 Age:overall -0.64 -1.62 0.29 86.83 1.03 796 76 102 6 TRUE 0.65
melanoma NRAS_Q61R ATR 27 20 50-65yrs -0.26 -1.82 0.84 1340.27 1.00 303 26 19 1 FALSE 0.16
melanoma NRAS_Q61R ATR 39 40 >65yrs -0.08 -1.20 0.91 1527.15 1.00 368 35 36 4 FALSE 0.05
melanoma NRAS_Q61R ATR 66 60 Age:overall -0.19 -1.70 0.96 1517.41 1.00 671 61 55 5 FALSE 0.11
melanoma NRAS_Q61R PDGFRA 27 20 50-65yrs -2.65 -5.89 -0.47 1110.90 1.00 308 27 20 0 TRUE 1.20
melanoma NRAS_Q61R PDGFRA 38 51 >65yrs -2.37 -4.84 -0.50 703.82 1.00 365 37 50 1 TRUE 1.43
melanoma NRAS_Q61R PDGFRA 65 71 Age:overall -2.44 -5.19 -0.33 1037.43 1.00 673 64 70 1 TRUE 1.27
melanoma NRAS_Q61R NSD1 27 18 50-65yrs -0.32 -1.98 0.86 1069.97 1.00 304 26 17 1 FALSE 0.19
melanoma NRAS_Q61R NSD1 38 35 >65yrs -0.23 -1.59 0.84 699.95 1.00 373 35 32 3 FALSE 0.15
melanoma NRAS_Q61R NSD1 65 53 Age:overall -0.29 -1.99 1.00 873.95 1.00 677 61 49 4 FALSE 0.16
melanoma NRAS_Q61R FLT4 27 23 50-65yrs -0.22 -2.08 1.02 1293.86 1.00 301 26 22 1 TRUE 0.11
melanoma NRAS_Q61R FLT4 38 60 >65yrs 0.45 -0.38 1.26 1217.68 1.00 361 30 52 8 TRUE 0.54
melanoma NRAS_Q61R FLT4 65 83 Age:overall 0.13 -1.58 1.43 1289.33 1.00 662 56 74 9 TRUE 0.06
melanoma NRAS_Q61R PTPRD 13 13 40-50yrs 0.03 -0.94 0.98 1396.51 1.00 67 11 11 2 FALSE 0.02
melanoma NRAS_Q61R PTPRD 28 73 50-65yrs -0.08 -0.87 0.66 1511.32 1.00 270 23 68 5 FALSE 0.07
melanoma NRAS_Q61R PTPRD 44 170 >65yrs -0.02 -0.62 0.58 1289.48 1.00 310 30 156 14 FALSE 0.03
melanoma NRAS_Q61R PTPRD 89 273 Age:overall 0.02 -0.75 0.79 1446.49 1.00 713 66 250 23 FALSE 0.01
melanoma NRAS_Q61R RET 27 14 50-65yrs -0.94 -2.97 0.82 1283.55 1.00 313 26 13 1 TRUE 0.49
melanoma NRAS_Q61R RET 38 35 >65yrs -1.14 -3.08 0.19 1229.08 1.00 371 37 34 1 TRUE 0.76
melanoma NRAS_Q61R RET 65 49 Age:overall -1.02 -3.00 0.71 1377.22 1.00 684 63 47 2 TRUE 0.56
melanoma NRAS_Q61R PIK3C2G 27 55 50-65yrs 0.28 -0.50 1.09 1438.72 1.00 266 21 49 6 FALSE 0.31
melanoma NRAS_Q61R PIK3C2G 37 128 >65yrs 0.18 -0.49 0.85 1468.68 1.00 313 26 117 11 FALSE 0.22
melanoma NRAS_Q61R PIK3C2G 64 183 Age:overall 0.22 -1.07 1.28 1534.09 1.00 579 47 166 17 FALSE 0.15
melanoma NRAS_Q61R CREBBP 27 21 50-65yrs -0.06 -1.36 1.06 1148.57 1.00 304 25 19 2 TRUE 0.04
melanoma NRAS_Q61R CREBBP 38 41 >65yrs -0.14 -1.32 0.88 1178.46 1.00 369 35 38 3 TRUE 0.10
melanoma NRAS_Q61R CREBBP 65 62 Age:overall -0.10 -1.50 1.21 1281.11 1.00 673 60 57 5 TRUE 0.06
melanoma NRAS_Q61R DOT1L 27 16 50-65yrs -0.08 -1.67 1.14 1165.36 1.00 306 26 15 1 FALSE 0.04
melanoma NRAS_Q61R DOT1L 38 37 >65yrs 0.13 -0.96 1.09 1447.10 1.00 374 34 33 4 FALSE 0.09
melanoma NRAS_Q61R DOT1L 65 53 Age:overall 0.02 -1.52 1.33 1457.99 1.00 680 60 48 5 FALSE 0.01
melanoma NRAS_Q61R PTPRS 26 15 50-65yrs -1.72 -4.96 0.27 1240.16 1.00 291 26 15 0 FALSE 0.68
melanoma NRAS_Q61R PTPRS 36 45 >65yrs -1.18 -2.91 0.22 1469.35 1.00 345 34 43 2 FALSE 0.86
melanoma NRAS_Q61R PTPRS 62 60 Age:overall -1.39 -4.00 0.66 1415.38 1.00 636 60 58 2 FALSE 0.63
melanoma NRAS_Q61R SMARCA4 27 25 50-65yrs 0.45 -0.56 1.37 1111.01 1.00 302 23 21 4 FALSE 0.43
melanoma NRAS_Q61R SMARCA4 38 38 >65yrs 0.24 -0.81 1.16 982.15 1.00 368 35 35 3 FALSE 0.20
melanoma NRAS_Q61R SMARCA4 65 63 Age:overall 0.33 -0.78 1.35 1183.26 1.00 670 58 56 7 FALSE 0.24
melanoma NRAS_Q61R PTPRT 14 20 40-50yrs 0.19 -0.79 1.19 1359.83 1.00 61 10 16 4 FALSE 0.14
melanoma NRAS_Q61R PTPRT 28 106 50-65yrs 0.44 -0.31 1.19 1519.81 1.00 257 16 94 12 FALSE 0.61
melanoma NRAS_Q61R PTPRT 43 238 >65yrs -0.52 -1.19 0.08 1520.31 1.00 284 31 226 12 FALSE 0.96
melanoma NRAS_Q61R PTPRT 85 364 Age:overall 0.03 -0.94 1.11 1499.67 1.00 602 57 336 28 FALSE 0.02
melanoma NRAS_Q61R HGF 27 22 50-65yrs -0.97 -2.67 0.41 1035.23 1.00 303 26 21 1 FALSE 0.65
melanoma NRAS_Q61R HGF 38 53 >65yrs -1.00 -2.47 0.12 1269.25 1.00 359 36 51 2 FALSE 0.88
melanoma NRAS_Q61R HGF 65 75 Age:overall -0.94 -2.63 0.51 1115.36 1.00 662 62 72 3 FALSE 0.60
melanoma NRAS_Q61R ALK 27 45 50-65yrs 0.31 -0.62 1.24 1054.08 1.00 297 21 39 6 TRUE 0.31
melanoma NRAS_Q61R ALK 38 75 >65yrs -0.01 -0.87 0.75 983.46 1.00 348 33 70 5 TRUE 0.01
melanoma NRAS_Q61R ALK 65 120 Age:overall 0.16 -0.91 1.19 1383.41 1.00 645 54 109 11 TRUE 0.11
melanoma NRAS_Q61R BAP1 27 24 50-65yrs -2.05 -4.95 -0.03 836.44 1.00 298 26 23 1 TRUE 0.99
melanoma NRAS_Q61R BAP1 38 36 >65yrs -2.37 -5.86 -0.44 959.01 1.00 367 38 36 0 TRUE 1.11
melanoma NRAS_Q61R BAP1 65 60 Age:overall -2.20 -5.30 -0.23 795.92 1.00 665 64 59 1 TRUE 1.07
melanoma NRAS_Q61R PTEN 13 11 40-50yrs -0.11 -1.36 0.82 1334.08 1.00 69 13 11 0 TRUE 0.07
melanoma NRAS_Q61R PTEN 27 27 50-65yrs 0.03 -0.89 0.91 1150.98 1.00 302 24 24 3 TRUE 0.02
melanoma NRAS_Q61R PTEN 38 35 >65yrs 0.03 -0.83 0.86 1125.45 1.00 373 34 31 4 TRUE 0.02
melanoma NRAS_Q61R PTEN 78 73 Age:overall -0.02 -1.00 0.87 1376.02 1.00 744 71 66 7 TRUE 0.01
melanoma NRAS_Q61R CTNNB1 27 17 50-65yrs -0.29 -1.76 0.92 1402.18 1.00 310 26 16 1 TRUE 0.17
melanoma NRAS_Q61R CTNNB1 38 34 >65yrs -0.18 -1.40 0.81 821.43 1.00 374 35 31 3 TRUE 0.12
melanoma NRAS_Q61R CTNNB1 65 51 Age:overall -0.23 -1.79 0.96 1338.45 1.00 684 61 47 4 TRUE 0.13
melanoma NRAS_Q61R ARID1A 27 30 50-65yrs -0.36 -1.58 0.58 979.44 1.00 296 25 28 2 TRUE 0.29
melanoma NRAS_Q61R ARID1A 38 47 >65yrs -0.38 -1.52 0.50 784.95 1.00 363 35 44 3 TRUE 0.33
melanoma NRAS_Q61R ARID1A 65 77 Age:overall -0.37 -1.66 0.65 1071.37 1.00 659 60 72 5 TRUE 0.28
melanoma NRAS_Q61R IKZF1 27 36 50-65yrs -1.90 -4.60 -0.32 941.36 1.00 290 27 36 0 TRUE 1.05
melanoma NRAS_Q61R IKZF1 38 56 >65yrs -1.62 -3.46 -0.22 905.47 1.00 363 36 54 2 TRUE 1.31
melanoma NRAS_Q61R IKZF1 65 92 Age:overall -1.75 -3.95 -0.16 1011.15 1.00 653 63 90 2 TRUE 1.13
melanoma NRAS_Q61R TERT 13 55 40-50yrs 0.70 -0.62 1.64 1311.28 1.00 34 7 49 6 TRUE 0.65
melanoma NRAS_Q61R TERT 32 208 50-65yrs 1.62 0.74 2.99 1193.19 1.00 169 1 177 31 TRUE 2.30
melanoma NRAS_Q61R TERT 41 312 >65yrs 0.92 0.22 1.58 1516.91 1.00 187 10 281 31 TRUE 2.13
thyroid cancer NRAS_Q61R TERT 6 22 40-50yrs 0.57 -0.32 1.64 1445.96 1.00 20 1 17 5 TRUE 0.64
thyroid cancer NRAS_Q61R TERT 21 96 50-65yrs 0.29 -0.49 1.00 578.33 1.01 68 10 85 11 TRUE 0.36
thyroid cancer NRAS_Q61R TERT 29 134 >65yrs 0.56 -0.08 1.29 1469.67 1.00 59 6 111 23 TRUE 0.98
melanoma NRAS_Q61R TERT 90 614 Age:overall 1.06 0.21 1.94 1265.44 1.00 431 19 543 71 TRUE 1.77
thyroid cancer NRAS_Q61R TERT 56 252 Age:overall 0.47 -0.29 1.26 1458.42 1.00 147 17 213 39 TRUE 0.64
melanoma NRAS_Q61R FAT1 29 45 50-65yrs 0.72 -0.20 1.61 1333.27 1.00 289 21 37 8 FALSE 0.89
melanoma NRAS_Q61R FAT1 38 92 >65yrs -0.26 -1.19 0.53 1236.00 1.00 338 33 87 5 FALSE 0.24
melanoma NRAS_Q61R FAT1 67 137 Age:overall 0.22 -1.37 1.93 1629.25 1.00 627 54 124 13 FALSE 0.10
melanoma NRAS_Q61R CIC 27 18 50-65yrs -5.09 -11.59 -1.26 861.57 1.01 304 27 18 0 TRUE 1.25
melanoma NRAS_Q61R CIC 38 32 >65yrs -5.13 -11.67 -1.36 402.46 1.01 372 38 32 0 TRUE 1.25
melanoma NRAS_Q61R CIC 65 50 Age:overall -5.06 -11.60 -1.28 531.47 1.01 676 65 50 0 TRUE 1.28
melanoma NRAS_Q61R KDM6A 27 13 50-65yrs -0.80 -3.32 1.14 1477.52 1.00 310 26 12 1 FALSE 0.31
melanoma NRAS_Q61R KDM6A 38 15 >65yrs -0.98 -3.30 0.78 1348.05 1.00 388 37 14 1 FALSE 0.43
melanoma NRAS_Q61R KDM6A 68 71 Age:overall -1.22 -3.78 0.99 1376.01 1.00 771 66 69 2 FALSE 0.50
melanoma NRAS_Q61R POLE 27 21 50-65yrs 0.22 -0.96 1.27 1576.07 1.00 303 25 19 2 TRUE 0.16
melanoma NRAS_Q61R POLE 38 43 >65yrs 0.30 -0.70 1.16 1636.68 1.00 365 33 38 5 TRUE 0.28
melanoma NRAS_Q61R POLE 65 64 Age:overall 0.26 -0.93 1.39 1446.48 1.00 668 58 57 7 TRUE 0.18
melanoma NRAS_Q61R NOTCH2 26 18 50-65yrs -1.93 -4.87 0.36 1418.43 1.00 289 25 17 1 TRUE 0.80
melanoma NRAS_Q61R NOTCH2 36 41 >65yrs -2.59 -6.17 -0.50 1363.10 1.00 349 36 41 0 TRUE 1.04
melanoma NRAS_Q61R NOTCH2 62 59 Age:overall -2.22 -5.16 -0.01 1160.31 1.00 638 61 58 1 TRUE 0.95
melanoma NRAS_Q61R KMT2A 27 37 50-65yrs 0.17 -0.81 1.09 1420.15 1.00 296 23 33 4 FALSE 0.14
melanoma NRAS_Q61R KMT2A 39 90 >65yrs -0.03 -0.83 0.70 1534.24 1.00 346 32 83 7 FALSE 0.02
melanoma NRAS_Q61R KMT2A 66 127 Age:overall 0.10 -1.12 1.32 1479.65 1.00 642 55 116 11 FALSE 0.06
melanoma NRAS_Q61R PAK7 13 15 40-50yrs -0.37 -1.56 0.60 1313.65 1.00 59 12 14 1 FALSE 0.31
melanoma NRAS_Q61R PAK7 26 65 50-65yrs -0.19 -1.05 0.56 1308.79 1.00 260 21 60 5 FALSE 0.20
melanoma NRAS_Q61R PAK7 38 131 >65yrs -0.19 -0.83 0.45 1276.27 1.00 301 28 121 10 FALSE 0.24
melanoma NRAS_Q61R PAK7 77 211 Age:overall -0.25 -1.12 0.52 1366.67 1.00 620 61 195 16 FALSE 0.27
melanoma NRAS_Q61R BRCA2 28 22 50-65yrs 0.50 -0.87 1.72 1409.32 1.00 304 24 18 4 TRUE 0.35
melanoma NRAS_Q61R BRCA2 38 63 >65yrs -1.38 -3.54 -0.01 1317.39 1.00 356 37 62 1 TRUE 0.92
melanoma NRAS_Q61R BRCA2 66 85 Age:overall -0.39 -2.79 2.14 1535.55 1.00 660 61 80 5 TRUE 0.12
melanoma NRAS_Q61R NOTCH3 27 32 50-65yrs -0.85 -2.38 0.50 1456.76 1.00 295 25 30 2 TRUE 0.61
melanoma NRAS_Q61R NOTCH3 38 87 >65yrs -1.33 -2.71 -0.29 1500.53 1.00 341 36 85 2 TRUE 1.52
melanoma NRAS_Q61R NOTCH3 65 119 Age:overall -1.04 -2.63 0.73 1128.34 1.00 636 61 115 4 TRUE 0.70
melanoma NRAS_Q61R NOTCH4 26 48 50-65yrs -0.25 -1.21 0.71 1090.21 1.00 271 22 44 4 TRUE 0.22
melanoma NRAS_Q61R NOTCH4 37 92 >65yrs -0.44 -1.32 0.37 766.82 1.00 321 32 87 5 TRUE 0.50
melanoma NRAS_Q61R NOTCH4 63 140 Age:overall -0.34 -1.49 0.73 1448.69 1.00 592 54 131 9 TRUE 0.26
melanoma NRAS_Q61R CDKN2A 27 43 50-65yrs -0.64 -1.73 0.23 1445.80 1.00 289 25 41 2 TRUE 0.71
melanoma NRAS_Q61R CDKN2A 38 65 >65yrs -0.60 -1.64 0.22 1250.72 1.00 350 34 61 4 TRUE 0.71
melanoma NRAS_Q61R CDKN2A 69 120 Age:overall -0.64 -1.69 0.24 1327.50 1.00 707 63 114 6 TRUE 0.71
melanoma NRAS_Q61R EPHB1 27 19 50-65yrs -0.46 -1.88 0.78 197.17 1.03 304 26 18 1 FALSE 0.31
melanoma NRAS_Q61R EPHB1 38 39 >65yrs -0.36 -1.57 0.72 95.21 1.06 370 35 36 3 FALSE 0.27
melanoma NRAS_Q61R EPHB1 65 58 Age:overall -0.42 -1.85 0.82 222.50 1.03 674 61 54 4 FALSE 0.26
melanoma NRAS_Q61R IL7R 27 34 50-65yrs -0.84 -2.27 0.32 829.88 1.00 294 26 33 1 FALSE 0.71
melanoma NRAS_Q61R IL7R 38 51 >65yrs -0.74 -2.04 0.30 720.00 1.00 365 35 48 3 FALSE 0.65
melanoma NRAS_Q61R IL7R 65 85 Age:overall -0.77 -2.11 0.46 846.98 1.00 659 61 81 4 FALSE 0.61
melanoma NRAS_Q61R ATM 27 22 50-65yrs -0.13 -1.66 0.92 1220.89 1.00 307 26 21 1 TRUE 0.07
melanoma NRAS_Q61R ATM 39 47 >65yrs 0.27 -0.72 1.14 1458.89 1.00 364 33 41 6 TRUE 0.24
melanoma NRAS_Q61R ATM 66 69 Age:overall 0.10 -1.33 1.27 1203.44 1.00 671 59 62 7 TRUE 0.05
melanoma NRAS_Q61R MAP2K1 27 17 50-65yrs -0.98 -3.03 0.64 1014.44 1.00 305 26 16 1 TRUE 0.55
melanoma NRAS_Q61R MAP2K1 38 36 >65yrs -1.15 -3.22 0.20 683.67 1.01 368 37 35 1 TRUE 0.72
melanoma NRAS_Q61R MAP2K1 65 53 Age:overall -1.06 -3.14 0.65 817.69 1.00 673 63 51 2 TRUE 0.57
melanoma NRAS_Q61R RB1 27 15 50-65yrs 0.84 -0.32 1.75 880.22 1.00 314 25 13 2 TRUE 0.93
melanoma NRAS_Q61R RB1 38 24 >65yrs 0.96 0.03 1.82 590.61 1.01 387 33 19 5 TRUE 1.37
melanoma NRAS_Q61R RB1 65 39 Age:overall 0.89 -0.20 1.89 590.26 1.00 701 58 32 7 TRUE 0.91
melanoma NRAS_Q61R KMT2D 27 63 50-65yrs -0.14 -1.08 0.68 1307.34 1.00 279 23 59 4 FALSE 0.12
melanoma NRAS_Q61R KMT2D 43 140 >65yrs 0.05 -0.61 0.67 1385.84 1.00 326 30 127 13 FALSE 0.05
melanoma NRAS_Q61R KMT2D 70 203 Age:overall -0.04 -1.22 1.05 1390.48 1.00 605 53 186 17 FALSE 0.03
melanoma NRAS_Q61R APC 28 58 50-65yrs -0.89 -2.10 0.08 1016.00 1.00 288 26 56 2 TRUE 0.95
melanoma NRAS_Q61R APC 38 60 >65yrs -0.84 -1.97 0.14 1021.09 1.00 359 35 57 3 TRUE 0.92
melanoma NRAS_Q61R APC 66 118 Age:overall -0.86 -2.19 0.31 1097.49 1.00 647 61 113 5 TRUE 0.77
melanoma NRAS_Q61R ARID2 30 42 50-65yrs 0.42 -0.67 1.47 1563.04 1.00 293 23 35 7 FALSE 0.36
melanoma NRAS_Q61R ARID2 38 79 >65yrs -1.38 -3.15 -0.17 1375.89 1.00 344 37 78 1 FALSE 1.10
melanoma NRAS_Q61R ARID2 71 141 Age:overall -0.66 -2.65 0.76 1473.28 1.00 709 63 133 8 FALSE 0.36
melanoma NRAS_Q61R MTOR 27 21 50-65yrs 0.07 -1.18 1.19 876.36 1.00 303 24 18 3 TRUE 0.04
melanoma NRAS_Q61R MTOR 38 26 >65yrs -0.23 -1.69 0.88 937.84 1.00 381 37 25 1 TRUE 0.13
melanoma NRAS_Q61R MTOR 65 47 Age:overall -0.08 -1.55 1.17 1136.48 1.00 684 61 43 4 TRUE 0.04
melanoma NRAS_Q61R NOTCH1 27 15 50-65yrs -2.51 -6.04 -0.17 1465.25 1.00 311 27 15 0 TRUE 0.93
melanoma NRAS_Q61R NOTCH1 38 43 >65yrs -2.16 -4.87 -0.29 1190.32 1.00 368 37 42 1 TRUE 1.15
melanoma NRAS_Q61R NOTCH1 65 58 Age:overall -2.31 -5.56 0.02 1214.58 1.00 679 64 57 1 TRUE 0.99
melanoma NRAS_Q61R NTRK1 27 13 50-65yrs -0.85 -2.84 0.92 1455.55 1.00 312 26 12 1 TRUE 0.43
melanoma NRAS_Q61R NTRK1 38 35 >65yrs -1.14 -3.03 0.26 1340.04 1.00 370 37 34 1 TRUE 0.73
melanoma NRAS_Q61R NTRK1 65 48 Age:overall -0.98 -2.98 0.85 1499.53 1.00 682 63 46 2 TRUE 0.49
melanoma NRAS_Q61R SETD2 27 28 50-65yrs 0.50 -0.60 1.66 277.47 1.01 303 22 23 5 FALSE 0.39
melanoma NRAS_Q61R SETD2 38 54 >65yrs -0.46 -1.98 0.60 1060.11 1.00 361 36 52 2 FALSE 0.32
melanoma NRAS_Q61R SETD2 65 82 Age:overall 0.01 -1.76 1.60 1207.82 1.00 664 58 75 7 FALSE 0.00
melanoma NRAS_Q61R PBRM1 27 23 50-65yrs -0.95 -3.79 0.46 859.72 1.00 301 27 23 0 TRUE 0.39
melanoma NRAS_Q61R PBRM1 38 42 >65yrs -0.34 -1.56 0.83 263.21 1.01 370 34 38 4 TRUE 0.24
melanoma NRAS_Q61R PBRM1 65 65 Age:overall -0.62 -2.38 0.74 637.46 1.00 671 61 61 4 TRUE 0.34
melanoma NRAS_Q61R EPHA3 27 32 50-65yrs 0.17 -0.87 1.06 1569.10 1.00 298 24 29 3 FALSE 0.14
melanoma NRAS_Q61R EPHA3 39 67 >65yrs 0.22 -0.62 0.94 1529.18 1.00 357 32 60 7 FALSE 0.24
melanoma NRAS_Q61R EPHA3 66 99 Age:overall 0.20 -0.99 1.25 1516.66 1.00 655 56 89 10 FALSE 0.14
melanoma NRAS_Q61R KIT 27 22 50-65yrs -2.32 -5.39 -0.39 1061.45 1.00 306 27 22 0 TRUE 1.16
melanoma NRAS_Q61R KIT 38 40 >65yrs -2.14 -4.93 -0.36 1162.79 1.00 368 37 39 1 TRUE 1.23
melanoma NRAS_Q61R KIT 65 62 Age:overall -2.20 -5.03 -0.29 1033.67 1.00 674 64 61 1 TRUE 1.22
melanoma NRAS_Q61R KDR 27 38 50-65yrs -0.14 -1.46 0.75 1174.40 1.00 297 25 36 2 TRUE 0.09
melanoma NRAS_Q61R KDR 39 80 >65yrs 0.25 -0.52 0.99 1402.14 1.00 350 30 71 9 TRUE 0.29
melanoma NRAS_Q61R KDR 66 118 Age:overall 0.06 -1.13 1.16 1185.52 1.00 647 55 107 11 TRUE 0.04
melanoma NRAS_Q61R CSF1R 27 20 50-65yrs -0.07 -1.69 1.51 153.36 1.02 309 24 17 3 TRUE 0.03
melanoma NRAS_Q61R CSF1R 38 34 >65yrs -1.60 -6.36 0.26 1067.24 1.00 377 38 34 0 TRUE 0.47
melanoma NRAS_Q61R CSF1R 65 54 Age:overall -0.77 -3.60 1.34 988.89 1.00 686 62 51 3 TRUE 0.28
melanoma NRAS_Q61R PTCH1 27 15 50-65yrs -1.46 -4.19 0.29 1278.23 1.00 307 27 15 0 TRUE 0.64
melanoma NRAS_Q61R PTCH1 38 35 >65yrs -1.04 -2.95 0.39 1030.79 1.00 371 36 33 2 TRUE 0.66
melanoma NRAS_Q61R PTCH1 65 50 Age:overall -1.28 -3.49 0.41 1209.68 1.00 678 63 48 2 TRUE 0.63
melanoma NRAS_Q61R TET1 26 17 50-65yrs -0.62 -2.29 0.75 1188.66 1.00 292 25 16 1 FALSE 0.38
melanoma NRAS_Q61R TET1 36 36 >65yrs -0.62 -2.04 0.59 930.64 1.00 355 34 34 2 FALSE 0.46
melanoma NRAS_Q61R TET1 62 53 Age:overall -0.63 -2.29 0.79 1143.26 1.00 647 59 50 3 FALSE 0.38
melanoma NRAS_Q61R FGFR2 27 23 50-65yrs -0.44 -1.83 0.88 1563.98 1.00 309 25 21 2 TRUE 0.28
melanoma NRAS_Q61R FGFR2 38 53 >65yrs -0.75 -2.13 0.35 1023.69 1.00 365 36 51 2 TRUE 0.62
melanoma NRAS_Q61R FGFR2 65 76 Age:overall -0.62 -2.23 0.72 1421.43 1.00 674 61 72 4 TRUE 0.38
melanoma NRAS_Q61R TBX3 27 15 50-65yrs -1.68 -4.80 0.20 1135.27 1.00 307 27 15 0 FALSE 0.64
melanoma NRAS_Q61R TBX3 38 40 >65yrs -1.07 -2.88 0.38 1205.88 1.00 372 36 38 2 FALSE 0.71
melanoma NRAS_Q61R TBX3 65 55 Age:overall -1.34 -3.86 0.60 1060.32 1.00 679 63 53 2 FALSE 0.62
melanoma NRAS_Q61R DICER1 38 39 >65yrs 0.43 -0.68 1.36 1167.17 1.00 372 33 34 5 TRUE 0.38
melanoma NRAS_Q61R DICER1 38 39 Age:overall 0.32 -4.50 4.58 1407.91 1.00 372 33 34 5 TRUE 0.06
melanoma NRAS_Q61R NTRK3 27 29 50-65yrs -0.41 -1.64 0.69 1336.70 1.00 296 25 27 2 FALSE 0.32
melanoma NRAS_Q61R NTRK3 39 68 >65yrs -0.45 -1.49 0.46 1496.92 1.00 355 35 64 4 FALSE 0.45
melanoma NRAS_Q61R NTRK3 66 97 Age:overall -0.40 -1.75 0.92 1514.59 1.00 651 60 91 6 FALSE 0.25
melanoma NRAS_Q61R GRIN2A 13 12 40-50yrs -0.49 -1.77 0.64 1316.18 1.00 69 12 11 1 FALSE 0.37
melanoma NRAS_Q61R GRIN2A 29 93 50-65yrs -0.22 -0.99 0.55 1418.49 1.00 263 22 86 7 FALSE 0.23
melanoma NRAS_Q61R GRIN2A 41 192 >65yrs -0.37 -1.03 0.21 1488.16 1.00 299 29 180 12 FALSE 0.61
melanoma NRAS_Q61R GRIN2A 83 297 Age:overall -0.37 -1.33 0.55 1315.25 1.00 631 63 277 20 FALSE 0.36
melanoma NRAS_Q61R BRD4 27 16 50-65yrs -0.66 -2.23 0.70 220.69 1.01 307 26 15 1 FALSE 0.40
melanoma NRAS_Q61R BRD4 38 36 >65yrs -0.68 -2.21 0.60 271.31 1.01 373 36 34 2 FALSE 0.45
melanoma NRAS_Q61R BRD4 65 52 Age:overall -0.66 -2.32 0.84 278.88 1.00 680 62 49 3 FALSE 0.37
melanoma NRAS_Q61R ASXL1 27 14 50-65yrs -2.12 -5.77 0.06 1305.69 1.00 308 27 14 0 TRUE 0.82
melanoma NRAS_Q61R ASXL1 38 32 >65yrs -1.82 -4.58 0.08 1089.10 1.00 372 37 31 1 TRUE 0.90
melanoma NRAS_Q61R ASXL1 65 46 Age:overall -1.94 -5.00 0.19 1275.06 1.00 680 64 45 1 TRUE 0.85
melanoma NRAS_Q61R EP300 27 15 50-65yrs -1.64 -4.44 0.59 948.08 1.00 307 26 14 1 TRUE 0.70
melanoma NRAS_Q61R EP300 38 37 >65yrs -2.37 -5.55 -0.23 782.07 1.00 369 38 37 0 TRUE 0.95
melanoma NRAS_Q61R EP300 65 52 Age:overall -1.96 -4.76 0.40 737.76 1.00 676 64 51 1 TRUE 0.85
melanoma NRAS_Q61R ERBB4 13 12 40-50yrs -0.94 -3.35 0.52 1328.42 1.00 70 13 12 0 TRUE 0.46
melanoma NRAS_Q61R ERBB4 30 63 50-65yrs 0.53 -0.40 1.44 1090.30 1.00 287 20 53 10 TRUE 0.59
melanoma NRAS_Q61R ERBB4 38 114 >65yrs -0.84 -1.96 0.02 1193.98 1.00 328 34 110 4 TRUE 1.02
melanoma NRAS_Q61R ERBB4 81 189 Age:overall -0.44 -1.98 0.74 1364.60 1.00 685 67 175 14 TRUE 0.27
melanoma NRAS_Q61R MDC1 26 19 50-65yrs -0.59 -2.26 0.76 1475.49 1.00 289 25 18 1 FALSE 0.34
melanoma NRAS_Q61R MDC1 36 60 >65yrs -0.42 -1.54 0.57 1327.75 1.00 339 32 56 4 FALSE 0.36
melanoma NRAS_Q61R MDC1 62 79 Age:overall -0.42 -2.10 1.10 1328.12 1.00 628 57 74 5 FALSE 0.21
melanoma NRAS_Q61R GNAQ 27 19 50-65yrs -5.36 -11.73 -0.92 438.87 1.00 308 27 19 0 TRUE 1.32
melanoma NRAS_Q61R GNAQ 38 31 >65yrs -5.38 -11.81 -0.93 443.83 1.00 372 38 31 0 TRUE 1.32
melanoma NRAS_Q61R GNAQ 65 50 Age:overall -5.30 -11.73 -0.78 425.90 1.00 680 65 50 0 TRUE 1.29
melanoma NRAS_Q61R MED12 28 19 50-65yrs 0.61 -0.39 1.47 449.07 1.00 309 25 16 3 TRUE 0.69
melanoma NRAS_Q61R MED12 40 31 >65yrs 0.56 -0.44 1.34 297.44 1.01 378 36 27 4 TRUE 0.66
melanoma NRAS_Q61R MED12 68 50 Age:overall 0.58 -0.48 1.50 513.71 1.01 687 61 43 7 TRUE 0.58
melanoma NRAS_Q61R NF1 13 14 40-50yrs -1.02 -2.27 0.42 1476.65 1.00 65 11 12 2 TRUE 0.85
melanoma NRAS_Q61R NF1 27 93 50-65yrs -1.25 -2.29 -0.24 1377.58 1.00 262 24 90 3 TRUE 1.78
melanoma NRAS_Q61R NF1 39 183 >65yrs -1.70 -2.79 -0.81 1575.38 1.00 282 36 180 3 TRUE 3.30
melanoma NRAS_Q61R NF1 79 290 Age:overall -1.31 -2.44 -0.12 1375.32 1.00 609 71 282 8 TRUE 1.63
melanoma NRAS_Q61R FLT1 27 34 50-65yrs -0.26 -1.40 0.77 1120.76 1.00 293 25 32 2 FALSE 0.20
melanoma NRAS_Q61R FLT1 40 80 >65yrs -0.07 -0.92 0.67 1485.21 1.00 348 33 73 7 FALSE 0.07
melanoma NRAS_Q61R FLT1 67 114 Age:overall -0.18 -1.60 1.00 1424.49 1.00 641 58 105 9 FALSE 0.10
melanoma NRAS_Q61R RPTOR 27 17 50-65yrs -0.95 -2.78 0.43 597.48 1.00 306 26 16 1 FALSE 0.59
melanoma NRAS_Q61R RPTOR 38 29 >65yrs -1.01 -2.85 0.28 588.62 1.00 373 37 28 1 FALSE 0.69
melanoma NRAS_Q61R RPTOR 65 46 Age:overall -0.99 -2.87 0.46 397.97 1.00 679 63 44 2 FALSE 0.61
melanoma NRAS_Q61R SF3B1 27 43 50-65yrs -0.26 -1.19 0.68 56.41 1.06 281 24 40 3 TRUE 0.23
melanoma NRAS_Q61R SF3B1 38 36 >65yrs -0.27 -1.18 0.66 47.05 1.06 368 35 33 3 TRUE 0.23
melanoma NRAS_Q61R SF3B1 65 79 Age:overall -0.27 -1.34 0.84 91.08 1.04 649 59 73 6 TRUE 0.19
melanoma NRAS_Q61R ROS1 13 14 40-50yrs -0.52 -1.74 0.62 1454.72 1.00 65 12 13 1 TRUE 0.41
melanoma NRAS_Q61R ROS1 28 71 50-65yrs -0.05 -0.88 0.81 1490.49 1.00 278 21 64 7 TRUE 0.04
melanoma NRAS_Q61R ROS1 40 163 >65yrs -0.58 -1.34 0.16 1437.12 1.00 307 32 155 8 TRUE 0.91
melanoma NRAS_Q61R ROS1 81 248 Age:overall -0.39 -1.40 0.63 1454.43 1.00 650 65 232 16 TRUE 0.37
melanoma NRAS_Q61R FLT3 27 28 50-65yrs 0.15 -0.93 1.13 1374.01 1.00 302 24 25 3 TRUE 0.12
melanoma NRAS_Q61R FLT3 38 46 >65yrs 0.08 -0.88 0.93 1203.04 1.00 367 34 42 4 TRUE 0.07
melanoma NRAS_Q61R FLT3 65 74 Age:overall 0.12 -0.99 1.13 1393.75 1.00 669 58 67 7 TRUE 0.08
melanoma NRAS_Q61R AXL 27 15 50-65yrs -1.61 -4.28 0.52 1045.51 1.00 308 26 14 1 FALSE 0.68
melanoma NRAS_Q61R AXL 38 42 >65yrs -2.54 -6.19 -0.36 588.58 1.00 365 38 42 0 FALSE 1.00
melanoma NRAS_Q61R AXL 65 57 Age:overall -1.99 -5.28 0.44 830.86 1.00 673 64 56 1 FALSE 0.81
melanoma NRAS_Q61R PIK3CG 27 28 50-65yrs -0.23 -1.58 1.08 1432.75 1.00 298 24 25 3 FALSE 0.14
melanoma NRAS_Q61R PIK3CG 38 73 >65yrs -0.99 -2.29 0.05 1322.68 1.00 355 36 71 2 FALSE 0.96
melanoma NRAS_Q61R PIK3CG 65 101 Age:overall -0.62 -2.38 1.05 1410.21 1.00 653 60 96 5 FALSE 0.33
melanoma NRAS_Q61R EGFR 27 21 50-65yrs -0.09 -1.34 1.22 578.41 1.01 309 24 18 3 TRUE 0.05
melanoma NRAS_Q61R EGFR 38 39 >65yrs -0.62 -2.32 0.50 340.10 1.01 371 37 38 1 TRUE 0.40
melanoma NRAS_Q61R EGFR 65 60 Age:overall -0.34 -1.86 0.99 897.00 1.00 680 61 56 4 TRUE 0.19
melanoma NRAS_Q61R ARID1B 27 23 50-65yrs 0.44 -0.63 1.56 1488.57 1.00 307 23 19 4 TRUE 0.38
melanoma NRAS_Q61R ARID1B 38 35 >65yrs 0.09 -1.03 1.02 1400.01 1.00 371 35 32 3 TRUE 0.07
melanoma NRAS_Q61R ARID1B 68 71 Age:overall 0.18 -1.04 1.29 1459.87 1.00 749 61 64 7 TRUE 0.12
melanoma NRAS_Q61R GNA11 27 23 50-65yrs -2.03 -5.52 0.06 40.41 1.02 304 26 22 1 TRUE 0.78
melanoma NRAS_Q61R GNA11 38 22 >65yrs -2.25 -5.55 -0.12 51.08 1.02 382 38 22 0 TRUE 0.82
melanoma NRAS_Q61R GNA11 65 45 Age:overall -2.13 -5.50 -0.02 42.40 1.02 686 64 44 1 TRUE 0.82
melanoma NRAS_Q61R INSR 26 16 50-65yrs 0.04 -1.27 1.26 1261.03 1.00 291 24 14 2 FALSE 0.02
melanoma NRAS_Q61R INSR 36 47 >65yrs -0.21 -1.39 0.98 705.99 1.00 353 33 44 3 FALSE 0.14
melanoma NRAS_Q61R INSR 62 63 Age:overall -0.09 -1.71 1.37 1474.96 1.00 644 57 58 5 FALSE 0.04
melanoma NRAS_Q61R ERG 27 18 50-65yrs -4.92 -11.39 -0.91 67.69 1.06 304 27 18 0 FALSE 1.12
melanoma NRAS_Q61R ERG 38 30 >65yrs -4.90 -11.69 -0.89 65.82 1.06 377 38 30 0 FALSE 1.14
melanoma NRAS_Q61R ERG 65 48 Age:overall -4.86 -11.36 -0.86 67.38 1.06 681 65 48 0 FALSE 1.13
melanoma NRAS_Q61R MET 27 26 50-65yrs -1.19 -4.86 0.36 1199.39 1.00 302 27 26 0 TRUE 0.44
melanoma NRAS_Q61R MET 38 52 >65yrs -0.23 -1.39 0.76 1181.20 1.00 360 33 47 5 TRUE 0.17
melanoma NRAS_Q61R MET 65 78 Age:overall -0.68 -3.25 0.80 1345.77 1.00 662 60 73 5 TRUE 0.31
melanoma NRAS_Q61R BRAF 13 36 40-50yrs -2.83 -4.44 -1.54 1447.94 1.00 45 13 36 0 TRUE 3.90
melanoma NRAS_Q61R BRAF 27 120 50-65yrs -2.77 -4.32 -1.61 1325.38 1.00 215 26 119 1 TRUE 4.31
melanoma NRAS_Q61R BRAF 38 115 >65yrs -2.67 -4.13 -1.53 1392.58 1.00 302 36 113 2 TRUE 4.14
thyroid cancer NRAS_Q61R BRAF 6 18 40-50yrs -4.09 -6.63 -2.37 420.39 1.02 22 6 18 0 TRUE 3.88
thyroid cancer NRAS_Q61R BRAF 24 62 50-65yrs -4.11 -6.64 -2.42 435.07 1.02 101 24 62 0 TRUE 3.87
thyroid cancer NRAS_Q61R BRAF 31 85 >65yrs -4.05 -6.53 -2.40 400.41 1.02 98 30 84 1 TRUE 3.97
melanoma NRAS_Q61R BRAF 82 299 Age:overall -2.77 -4.22 -1.61 1336.40 1.00 612 79 296 3 TRUE 4.37
thyroid cancer NRAS_Q61R BRAF 61 165 Age:overall -4.08 -6.57 -2.46 398.39 1.02 221 60 164 1 TRUE 4.04
melanoma NRAS_Q61R TET2 27 35 50-65yrs -0.43 -1.59 0.54 1275.12 1.00 294 25 33 2 TRUE 0.37
melanoma NRAS_Q61R TET2 38 48 >65yrs -0.42 -1.59 0.52 1289.82 1.00 365 35 45 3 TRUE 0.38
melanoma NRAS_Q61R TET2 65 83 Age:overall -0.42 -1.65 0.60 1399.98 1.00 659 60 78 5 TRUE 0.35
melanoma NRAS_Q61R PDGFRB 27 16 50-65yrs -2.55 -6.19 -0.15 1297.70 1.00 306 27 16 0 TRUE 0.96
melanoma NRAS_Q61R PDGFRB 38 47 >65yrs -2.20 -4.85 -0.31 1199.57 1.00 370 37 46 1 TRUE 1.20
melanoma NRAS_Q61R PDGFRB 65 63 Age:overall -2.33 -5.65 -0.02 1282.01 1.00 676 64 62 1 TRUE 1.00
melanoma NRAS_Q61R CARD11 27 29 50-65yrs -1.32 -3.11 0.12 1221.78 1.00 296 26 28 1 FALSE 1.00
melanoma NRAS_Q61R CARD11 38 75 >65yrs -1.43 -2.85 -0.31 1467.42 1.00 346 36 73 2 FALSE 1.51
melanoma NRAS_Q61R CARD11 65 104 Age:overall -1.37 -3.20 0.18 1427.23 1.00 642 62 101 3 FALSE 1.01
melanoma NRAS_Q61R CBL 27 25 50-65yrs 0.88 -0.40 1.98 1453.74 1.00 302 22 20 5 TRUE 0.81
melanoma NRAS_Q61R CBL 38 52 >65yrs -2.92 -8.49 -0.28 1358.37 1.00 356 38 52 0 TRUE 0.77
melanoma NRAS_Q61R CBL 65 77 Age:overall -0.84 -4.55 1.97 1336.87 1.00 658 60 72 5 TRUE 0.22
melanoma NRAS_Q61R TP63 13 11 40-50yrs 0.10 -0.70 1.17 1446.55 1.00 66 10 8 3 FALSE 0.08
melanoma NRAS_Q61R TP63 27 59 50-65yrs -0.01 -0.79 0.73 1472.28 1.00 263 22 54 5 FALSE 0.01
melanoma NRAS_Q61R TP63 37 91 >65yrs -0.11 -0.88 0.58 1479.74 1.00 318 31 85 6 FALSE 0.12
melanoma NRAS_Q61R TP63 77 161 Age:overall -0.01 -0.77 0.78 1463.95 1.00 647 63 147 14 FALSE 0.01
melanoma NRAS_Q61R GLI1 27 18 50-65yrs -0.47 -1.98 0.98 1325.65 1.00 287 25 16 2 FALSE 0.26
melanoma NRAS_Q61R GLI1 38 40 >65yrs -0.98 -2.71 0.28 1097.37 1.00 344 37 39 1 FALSE 0.70
melanoma NRAS_Q61R GLI1 65 58 Age:overall -0.73 -2.52 0.83 1354.06 1.00 631 62 55 3 FALSE 0.41
melanoma NRAS_Q61R ZFHX3 27 32 50-65yrs -0.16 -1.32 0.97 1366.26 1.00 275 24 29 3 FALSE 0.10
melanoma NRAS_Q61R ZFHX3 39 65 >65yrs -0.13 -1.01 0.69 1344.75 1.00 331 33 59 6 FALSE 0.12
melanoma NRAS_Q61R ZFHX3 69 139 Age:overall -0.46 -2.07 0.90 1516.72 1.00 673 60 130 9 FALSE 0.27
melanoma NRAS_Q61R MGA 27 38 50-65yrs -1.23 -2.62 -0.07 912.46 1.00 272 26 37 1 FALSE 1.15
melanoma NRAS_Q61R MGA 38 50 >65yrs -1.18 -2.52 -0.05 1108.13 1.00 337 36 48 2 FALSE 1.16
melanoma NRAS_Q61R MGA 65 88 Age:overall -1.20 -2.65 0.03 1063.21 1.00 609 62 85 3 FALSE 1.02
melanoma NRAS_Q61R KMT2B 17 29 50-65yrs -0.63 -2.13 0.43 1409.07 1.00 154 16 28 1 FALSE 0.47
melanoma NRAS_Q61R KMT2B 28 56 >65yrs -0.37 -1.37 0.51 1327.82 1.00 201 23 51 5 FALSE 0.34
melanoma NRAS_Q61R KMT2B 45 85 Age:overall -0.48 -1.75 0.72 1376.31 1.00 355 39 79 6 FALSE 0.33
melanoma NRAS_Q61R ANKRD11 26 25 50-65yrs -0.33 -1.64 0.96 1497.21 1.00 267 23 22 3 FALSE 0.20
melanoma NRAS_Q61R ANKRD11 36 44 >65yrs -0.86 -2.55 0.33 1249.20 1.00 325 35 43 1 FALSE 0.62
melanoma NRAS_Q61R ANKRD11 62 69 Age:overall -0.58 -2.08 0.85 1184.70 1.00 592 58 65 4 FALSE 0.37
melanoma NRAS_Q61R PGR 26 19 50-65yrs -2.23 -5.32 -0.25 1071.41 1.00 269 26 19 0 FALSE 1.03
melanoma NRAS_Q61R PGR 36 33 >65yrs -2.03 -4.82 -0.17 1055.93 1.00 327 35 32 1 FALSE 1.06
melanoma NRAS_Q61R PGR 62 52 Age:overall -2.11 -5.05 -0.14 1096.83 1.00 596 61 51 1 FALSE 1.01
melanoma NRAS_Q61R PLCG2 26 17 50-65yrs -0.30 -1.98 0.95 1366.30 1.00 274 25 16 1 FALSE 0.17
melanoma NRAS_Q61R PLCG2 36 41 >65yrs -0.09 -1.30 0.92 1319.85 1.00 322 32 37 4 FALSE 0.06
melanoma NRAS_Q61R PLCG2 62 58 Age:overall -0.20 -1.72 1.30 1361.84 1.00 596 57 53 5 FALSE 0.10
melanoma NRAS_Q61R PREX2 6 11 40-50yrs -0.44 -1.63 0.62 781.16 1.01 30 5 10 1 FALSE 0.37
melanoma NRAS_Q61R PREX2 17 55 50-65yrs -0.12 -1.02 0.95 1249.72 1.00 141 10 48 7 FALSE 0.10
melanoma NRAS_Q61R PREX2 27 100 >65yrs -0.71 -1.77 0.06 63.70 1.05 189 24 97 3 FALSE 0.82
melanoma NRAS_Q61R PREX2 50 166 Age:overall -0.42 -1.41 0.47 746.10 1.01 360 39 155 11 FALSE 0.43
melanoma NRAS_Q61R EPHA7 27 38 50-65yrs -1.50 -3.24 -0.08 1253.30 1.00 271 26 37 1 FALSE 1.20
melanoma NRAS_Q61R EPHA7 38 105 >65yrs -1.50 -2.73 -0.49 1367.61 1.00 303 35 102 3 FALSE 2.02
melanoma NRAS_Q61R EPHA7 65 143 Age:overall -1.49 -3.23 0.14 1375.66 1.00 574 61 139 4 FALSE 1.10
pancreatic cancer KRAS_G12R TP53 7 60 40-50yrs 0.40 -0.39 1.10 1386.97 1.00 63 3 56 4 TRUE 0.53
pancreatic cancer KRAS_G12R TP53 71 384 50-65yrs 0.69 0.22 1.19 1478.94 1.00 237 17 330 54 TRUE 2.32
pancreatic cancer KRAS_G12R TP53 99 495 >65yrs 0.51 0.08 0.91 1658.46 1.00 261 29 425 70 TRUE 1.76
pancreatic cancer KRAS_G12R TP53 177 939 Age:overall 0.54 -0.04 1.16 1062.05 1.00 561 49 811 128 TRUE 1.14
pancreatic cancer KRAS_G12R RNF43 70 21 50-65yrs -0.27 -1.44 0.77 1328.25 1.00 528 68 19 2 TRUE 0.20
pancreatic cancer KRAS_G12R RNF43 94 52 >65yrs -0.16 -1.00 0.61 1373.17 1.00 622 88 46 6 TRUE 0.15
pancreatic cancer KRAS_G12R RNF43 164 73 Age:overall -0.19 -1.43 1.25 1376.57 1.00 1150 156 65 8 TRUE 0.11
pancreatic cancer KRAS_G12R ARID1A 70 50 50-65yrs -1.62 -2.92 -0.60 1221.63 1.00 499 69 49 1 TRUE 1.98
pancreatic cancer KRAS_G12R ARID1A 94 68 >65yrs -1.52 -2.72 -0.52 1253.55 1.00 605 91 65 3 TRUE 2.16
pancreatic cancer KRAS_G12R ARID1A 164 118 Age:overall -1.53 -2.87 -0.45 1235.33 1.00 1104 160 114 4 TRUE 1.75
pancreatic cancer KRAS_G12R KDM6A 70 19 50-65yrs -0.43 -1.87 0.59 870.89 1.00 529 69 18 1 FALSE 0.30
pancreatic cancer KRAS_G12R KDM6A 94 38 >65yrs -0.19 -1.26 0.70 545.70 1.00 631 89 33 5 FALSE 0.17
pancreatic cancer KRAS_G12R KDM6A 164 57 Age:overall -0.30 -1.64 0.85 945.57 1.00 1160 158 51 6 FALSE 0.19
pancreatic cancer KRAS_G12R CDKN2A 7 11 40-50yrs 0.37 -0.76 1.44 1483.94 1.00 109 6 10 1 TRUE 0.30
pancreatic cancer KRAS_G12R CDKN2A 72 104 50-65yrs 0.75 0.22 1.27 1548.39 1.00 486 51 83 21 TRUE 2.23
pancreatic cancer KRAS_G12R CDKN2A 101 175 >65yrs 0.21 -0.27 0.68 1690.21 1.00 542 77 151 24 TRUE 0.43
pancreatic cancer KRAS_G12R CDKN2A 180 290 Age:overall 0.45 -0.38 1.29 1482.22 1.00 1137 134 244 46 TRUE 0.56
pancreatic cancer KRAS_G12R SMAD4 7 18 40-50yrs 0.69 0.12 1.25 1335.41 1.00 103 5 16 2 TRUE 1.89
pancreatic cancer KRAS_G12R SMAD4 72 113 50-65yrs 0.76 0.35 1.16 1026.43 1.00 473 50 91 22 TRUE 3.43
pancreatic cancer KRAS_G12R SMAD4 100 139 >65yrs 0.71 0.32 1.10 892.40 1.00 576 73 112 27 TRUE 3.44
pancreatic cancer KRAS_G12R SMAD4 179 270 Age:overall 0.72 0.25 1.19 1054.35 1.00 1152 128 219 51 TRUE 2.73
pancreatic cancer KRAS_G12R KMT2D 70 27 50-65yrs -0.50 -1.61 0.44 1168.79 1.00 523 68 25 2 FALSE 0.46
pancreatic cancer KRAS_G12R KMT2D 95 32 >65yrs -0.49 -1.52 0.44 1094.05 1.00 640 92 29 3 FALSE 0.48
pancreatic cancer KRAS_G12R KMT2D 165 59 Age:overall -0.49 -1.60 0.49 1230.53 1.00 1163 160 54 5 FALSE 0.45
pancreatic cancer KRAS_G12R GNAS 71 15 50-65yrs -0.17 -1.51 1.03 1337.56 1.00 550 69 13 2 TRUE 0.11
pancreatic cancer KRAS_G12R GNAS 99 42 >65yrs -0.33 -1.45 0.58 1414.81 1.00 648 95 38 4 TRUE 0.28
pancreatic cancer KRAS_G12R GNAS 170 57 Age:overall -0.25 -1.70 1.20 1212.44 1.00 1198 164 51 6 TRUE 0.13
pancreatic cancer KRAS_G12R DAXX 67 23 50-65yrs -5.43 -11.64 -1.29 371.94 1.01 501 67 23 0 TRUE 1.35
pancreatic cancer KRAS_G12R DAXX 89 21 >65yrs -5.45 -11.65 -1.29 382.05 1.01 625 89 21 0 TRUE 1.35
pancreatic cancer KRAS_G12R DAXX 156 44 Age:overall -5.37 -11.42 -1.32 352.25 1.01 1126 156 44 0 TRUE 1.37
pancreatic cancer KRAS_G12R MEN1 70 39 50-65yrs -5.79 -12.48 -1.70 1267.52 1.00 508 70 39 0 TRUE 1.41
pancreatic cancer KRAS_G12R MEN1 94 28 >65yrs -5.76 -11.87 -1.67 1344.02 1.00 636 94 28 0 TRUE 1.44
pancreatic cancer KRAS_G12R MEN1 164 67 Age:overall -5.69 -11.96 -1.73 1334.33 1.00 1144 164 67 0 TRUE 1.42
pancreatic cancer KRAS_Q61H TP53 14 384 50-65yrs 0.67 -0.14 1.72 1522.51 1.00 252 2 372 12 TRUE 0.84
pancreatic cancer KRAS_Q61H TP53 41 495 >65yrs 0.77 0.11 1.44 1425.21 1.00 281 9 463 32 TRUE 1.63
pancreatic cancer KRAS_Q61H TP53 60 939 Age:overall 0.52 -0.58 1.52 1513.41 1.00 595 15 894 45 TRUE 0.48
pancreatic cancer KRAS_Q61H RNF43 14 21 50-65yrs -2.03 -6.38 0.62 1486.84 1.00 582 14 21 0 TRUE 0.60
pancreatic cancer KRAS_Q61H RNF43 40 52 >65yrs -1.70 -4.64 0.17 1418.47 1.00 671 39 51 1 TRUE 0.75
pancreatic cancer KRAS_Q61H RNF43 54 73 Age:overall -1.83 -5.27 0.70 1452.96 1.00 1253 53 72 1 TRUE 0.62
pancreatic cancer KRAS_Q61H ARID1A 14 50 50-65yrs 0.27 -1.06 1.54 1434.69 1.00 556 12 48 2 TRUE 0.17
pancreatic cancer KRAS_Q61H ARID1A 41 68 >65yrs 0.12 -0.95 1.06 1428.65 1.00 659 37 64 4 TRUE 0.09
pancreatic cancer KRAS_Q61H ARID1A 55 118 Age:overall 0.19 -1.30 1.57 1546.69 1.00 1215 49 112 6 TRUE 0.10
pancreatic cancer KRAS_Q61H KDM6A 14 19 50-65yrs -0.13 -2.24 1.83 1514.98 1.00 585 13 18 1 FALSE 0.04
pancreatic cancer KRAS_Q61H KDM6A 40 38 >65yrs -0.64 -2.53 0.90 1258.95 1.00 681 39 37 1 FALSE 0.32
pancreatic cancer KRAS_Q61H KDM6A 54 57 Age:overall -0.39 -2.51 1.55 1650.08 1.00 1266 52 55 2 FALSE 0.15
pancreatic cancer KRAS_Q61H CDKN2A 14 104 50-65yrs -0.54 -2.00 0.59 1421.84 1.00 524 13 103 1 TRUE 0.39
pancreatic cancer KRAS_Q61H CDKN2A 40 175 >65yrs -0.17 -0.99 0.54 1545.29 1.00 587 32 167 8 TRUE 0.18
pancreatic cancer KRAS_Q61H CDKN2A 59 290 Age:overall -0.29 -1.50 0.87 1474.46 1.00 1222 49 280 10 TRUE 0.20
pancreatic cancer KRAS_Q61H SMAD4 15 113 50-65yrs 0.19 -0.62 0.93 1433.58 1.00 511 12 110 3 TRUE 0.19
pancreatic cancer KRAS_Q61H SMAD4 40 139 >65yrs 0.22 -0.47 0.86 1365.15 1.00 617 32 131 8 TRUE 0.29
pancreatic cancer KRAS_Q61H SMAD4 60 270 Age:overall 0.26 -0.55 1.03 1460.57 1.00 1233 47 257 13 TRUE 0.28
pancreatic cancer KRAS_Q61H KMT2D 14 27 50-65yrs -0.92 -3.69 1.22 1001.96 1.00 578 13 26 1 FALSE 0.32
pancreatic cancer KRAS_Q61H KMT2D 40 32 >65yrs -1.79 -5.99 0.36 1521.48 1.00 692 40 32 0 FALSE 0.61
pancreatic cancer KRAS_Q61H KMT2D 54 59 Age:overall -1.32 -4.53 1.06 1468.44 1.00 1270 53 58 1 FALSE 0.44
pancreatic cancer KRAS_Q61H GNAS 14 15 50-65yrs -1.01 -4.57 1.37 1316.47 1.00 605 14 15 0 TRUE 0.28
pancreatic cancer KRAS_Q61H GNAS 40 42 >65yrs -0.47 -2.52 0.97 1550.85 1.00 705 38 40 2 TRUE 0.23
pancreatic cancer KRAS_Q61H GNAS 54 57 Age:overall -0.69 -3.48 1.57 1572.26 1.00 1310 52 55 2 TRUE 0.23
pancreatic cancer KRAS_Q61H DAXX 14 23 50-65yrs -4.85 -11.76 -0.23 816.17 1.00 554 14 23 0 TRUE 0.92
pancreatic cancer KRAS_Q61H DAXX 40 21 >65yrs -4.86 -11.62 -0.28 903.22 1.00 674 40 21 0 TRUE 0.95
pancreatic cancer KRAS_Q61H DAXX 54 44 Age:overall -4.74 -11.02 -0.14 732.16 1.00 1228 54 44 0 TRUE 0.98
pancreatic cancer KRAS_Q61H MEN1 14 39 50-65yrs -5.03 -12.35 -0.49 1106.38 1.00 564 14 39 0 TRUE 1.00
pancreatic cancer KRAS_Q61H MEN1 40 28 >65yrs -5.07 -12.66 -0.66 1018.58 1.00 690 40 28 0 TRUE 1.03
pancreatic cancer KRAS_Q61H MEN1 54 67 Age:overall -4.89 -11.83 -0.27 1137.49 1.00 1254 54 67 0 TRUE 0.99
colorectal cancer KRAS_G12S APC 11 246 <40yrs 0.57 -0.07 1.41 567.77 1.00 88 1 236 10 TRUE 0.96
colorectal cancer KRAS_G12S APC 10 494 40-50yrs 0.49 -0.14 1.25 533.92 1.00 167 2 486 8 TRUE 0.80
colorectal cancer KRAS_G12S APC 24 1094 50-65yrs 0.48 -0.14 1.21 524.74 1.00 364 6 1076 18 TRUE 0.78
colorectal cancer KRAS_G12S APC 22 704 >65yrs 0.55 -0.07 1.31 525.47 1.00 260 3 685 19 TRUE 0.95
colorectal cancer KRAS_G12S APC 67 2538 Age:overall 0.52 -0.10 1.24 518.93 1.00 879 12 2483 55 TRUE 0.91
colorectal cancer KRAS_G12A SPEN 40 121 White -4.75 -11.13 -0.97 327.80 1.01 1612 40 121 0 FALSE 1.09
non-small cell lung cancer KRAS_G12A SPEN 81 101 White 0.27 -0.92 1.26 1212.07 1.00 2769 77 97 4 FALSE 0.21
colorectal cancer KRAS_G12A SPEN 44 132 Race:overall -4.66 -11.08 -0.80 339.57 1.01 1746 44 132 0 FALSE 1.07
non-small cell lung cancer KRAS_G12A SPEN 81 101 Race:overall 0.21 -4.42 4.74 1572.21 1.00 2769 77 97 4 FALSE 0.04
non-small cell lung cancer KRAS_G12A KMT2C 81 185 White -0.77 -2.15 0.30 1455.63 1.00 2670 78 182 3 FALSE 0.66
non-small cell lung cancer KRAS_G12A KMT2C 85 210 Race:overall -0.84 -2.86 0.95 1239.13 1.00 3164 82 207 3 FALSE 0.41
colorectal cancer KRAS_G12A TP53 44 1350 White -0.63 -1.19 -0.13 1382.93 1.00 662 22 1328 22 TRUE 1.60
non-small cell lung cancer KRAS_G12A TP53 86 1617 White -0.83 -1.28 -0.38 1431.60 1.00 1450 58 1589 28 TRUE 3.59
colorectal cancer KRAS_G12A TP53 55 1713 Race:overall -0.58 -1.27 0.10 1489.35 1.00 827 26 1684 29 TRUE 1.03
non-small cell lung cancer KRAS_G12A TP53 93 2050 Race:overall -0.99 -1.83 -0.23 1333.09 1.00 1828 63 2020 30 TRUE 1.84
colorectal cancer KRAS_G12A ATRX 40 96 White 0.23 -1.21 1.30 1658.98 1.00 1622 37 93 3 TRUE 0.14
non-small cell lung cancer KRAS_G12A ATRX 82 186 White -0.15 -1.19 0.72 1099.73 1.00 2679 77 181 5 TRUE 0.12
colorectal cancer KRAS_G12A ATRX 40 96 Race:overall 0.18 -4.24 4.54 1412.29 1.00 1622 37 93 3 TRUE 0.03
non-small cell lung cancer KRAS_G12A ATRX 84 197 Race:overall -0.28 -2.62 1.55 1407.32 1.00 2862 79 192 5 TRUE 0.10
colorectal cancer KRAS_G12A ATR 40 88 White -4.70 -11.35 -0.56 758.72 1.00 1635 40 88 0 FALSE 1.01
non-small cell lung cancer KRAS_G12A ATR 82 103 White 0.51 -0.57 1.36 1512.90 1.00 2742 77 98 5 FALSE 0.52
colorectal cancer KRAS_G12A ATR 43 99 Race:overall -4.55 -10.99 -0.34 718.38 1.00 1774 43 99 0 FALSE 0.95
non-small cell lung cancer KRAS_G12A ATR 82 103 Race:overall 0.34 -4.66 4.68 1409.89 1.00 2742 77 98 5 FALSE 0.06
colorectal cancer KRAS_G12A PDGFRA 44 44 White -5.42 -15.06 0.14 351.53 1.01 1844 44 44 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A PDGFRA 84 112 White -0.33 -1.78 0.75 1181.21 1.00 2822 81 109 3 TRUE 0.21
colorectal cancer KRAS_G12A PDGFRA 44 44 Race:overall -4.08 -10.90 3.05 102.25 1.03 1844 44 44 0 TRUE 0.55
non-small cell lung cancer KRAS_G12A PDGFRA 89 137 Race:overall -0.49 -2.50 1.12 1260.19 1.00 3322 86 134 3 TRUE 0.23
colorectal cancer KRAS_G12A FBXW7 45 254 White 0.68 0.03 1.30 1115.53 1.00 1676 34 243 11 TRUE 1.42
non-small cell lung cancer KRAS_G12A FBXW7 84 64 White -1.05 -3.77 0.82 1314.07 1.00 2868 83 63 1 TRUE 0.43
colorectal cancer KRAS_G12A FBXW7 54 334 Race:overall 0.63 -0.18 1.35 1216.00 1.00 2059 41 321 13 TRUE 0.97
non-small cell lung cancer KRAS_G12A FBXW7 84 64 Race:overall -0.81 -5.37 4.30 1367.04 1.00 2868 83 63 1 TRUE 0.14
colorectal cancer KRAS_G12A MAP3K1 40 70 White -0.92 -3.55 0.95 1054.15 1.00 1639 39 69 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A MAP3K1 81 56 White 0.00 -1.88 1.32 1561.82 1.00 2784 79 54 2 FALSE 0.00
colorectal cancer KRAS_G12A MAP3K1 40 70 Race:overall -0.73 -5.71 4.16 1249.10 1.00 1639 39 69 1 FALSE 0.12
non-small cell lung cancer KRAS_G12A MAP3K1 81 56 Race:overall 0.00 -4.38 4.58 1241.82 1.00 2784 79 54 2 FALSE 0.00
colorectal cancer KRAS_G12A NSD1 40 71 White -5.62 -16.00 -0.30 1083.40 1.00 1641 40 71 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A NSD1 81 67 White 0.70 -0.46 1.64 1430.51 1.00 2774 77 63 4 FALSE 0.73
colorectal cancer KRAS_G12A NSD1 40 71 Race:overall -4.05 -12.00 2.54 926.32 1.00 1641 40 71 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A NSD1 81 67 Race:overall 0.62 -3.81 4.96 1556.09 1.00 2774 77 63 4 FALSE 0.12
colorectal cancer KRAS_G12A FLT4 40 115 White -1.47 -4.27 0.38 1187.38 1.00 1601 39 114 1 TRUE 0.68
non-small cell lung cancer KRAS_G12A FLT4 82 84 White 0.46 -0.76 1.42 1033.74 1.00 2758 78 80 4 TRUE 0.38
colorectal cancer KRAS_G12A FLT4 40 115 Race:overall -1.25 -5.81 3.45 1509.74 1.00 1601 39 114 1 TRUE 0.24
non-small cell lung cancer KRAS_G12A FLT4 82 84 Race:overall 0.40 -4.06 4.40 1554.91 1.00 2758 78 80 4 TRUE 0.07
colorectal cancer KRAS_G12A PTPRD 40 85 White 0.68 -0.57 1.70 1277.57 1.00 1635 36 81 4 FALSE 0.63
non-small cell lung cancer KRAS_G12A PTPRD 82 320 White 0.17 -0.55 0.83 1486.85 1.00 2574 72 310 10 FALSE 0.22
colorectal cancer KRAS_G12A PTPRD 40 85 Race:overall 0.60 -3.96 4.72 1399.11 1.00 1635 36 81 4 FALSE 0.11
non-small cell lung cancer KRAS_G12A PTPRD 89 386 Race:overall 0.31 -0.95 1.55 1432.53 1.00 3211 77 374 12 FALSE 0.21
colorectal cancer KRAS_G12A RET 44 58 White -5.39 -13.35 -0.19 448.68 1.01 1831 44 58 0 TRUE 0.27
non-small cell lung cancer KRAS_G12A RET 84 81 White -1.35 -4.06 0.52 811.42 1.00 2847 83 80 1 TRUE 0.56
colorectal cancer KRAS_G12A RET 44 58 Race:overall -4.06 -10.81 2.69 158.47 1.02 1831 44 58 0 TRUE 0.67
non-small cell lung cancer KRAS_G12A RET 84 81 Race:overall -1.06 -5.53 4.01 1245.84 1.00 2847 83 80 1 TRUE 0.19
colorectal cancer KRAS_G12A KDM5A 40 74 White -5.78 -16.56 -0.21 1378.53 1.00 1641 40 74 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A KDM5A 81 62 White 0.45 -0.93 1.57 941.47 1.00 2781 78 59 3 FALSE 0.34
colorectal cancer KRAS_G12A KDM5A 40 74 Race:overall -3.97 -11.47 2.82 1034.62 1.00 1641 40 74 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A KDM5A 81 62 Race:overall 0.41 -4.49 4.91 1297.25 1.00 2781 78 59 3 FALSE 0.07
colorectal cancer KRAS_G12A PIK3C2G 41 65 White 0.55 -1.01 1.68 1144.35 1.00 1644 38 62 3 FALSE 0.38
non-small cell lung cancer KRAS_G12A PIK3C2G 81 113 White 0.39 -0.65 1.25 1304.70 1.00 2736 76 108 5 FALSE 0.37
colorectal cancer KRAS_G12A PIK3C2G 41 65 Race:overall 0.49 -4.11 4.69 1668.76 1.00 1644 38 62 3 FALSE 0.09
non-small cell lung cancer KRAS_G12A PIK3C2G 81 113 Race:overall 0.34 -4.10 4.47 1451.07 1.00 2736 76 108 5 FALSE 0.06
non-small cell lung cancer KRAS_G12A TSHR 81 58 White 0.02 -1.78 1.32 652.03 1.00 2783 79 56 2 TRUE 0.01
non-small cell lung cancer KRAS_G12A TSHR 81 58 Race:overall 0.04 -4.43 4.78 1444.23 1.00 2783 79 56 2 TRUE 0.01
colorectal cancer KRAS_G12A CREBBP 40 148 White -0.90 -2.73 0.21 149.41 1.02 1588 38 146 2 TRUE 0.61
non-small cell lung cancer KRAS_G12A CREBBP 81 122 White -0.26 -1.68 0.87 1119.36 1.00 2727 78 119 3 TRUE 0.16
colorectal cancer KRAS_G12A CREBBP 49 183 Race:overall -0.92 -2.73 0.23 147.00 1.02 1980 47 181 2 TRUE 0.61
non-small cell lung cancer KRAS_G12A CREBBP 81 122 Race:overall -0.16 -5.14 4.31 1545.27 1.00 2727 78 119 3 TRUE 0.03
non-small cell lung cancer KRAS_G12A BRIP1 81 53 White 0.61 -0.73 1.67 1180.72 1.00 2787 78 50 3 TRUE 0.51
non-small cell lung cancer KRAS_G12A BRIP1 81 53 Race:overall 0.55 -3.29 4.39 1415.57 1.00 2787 78 50 3 TRUE 0.12
colorectal cancer KRAS_G12A AXIN2 40 87 White 0.96 -0.08 1.96 1167.02 1.00 1631 35 82 5 TRUE 1.19
non-small cell lung cancer KRAS_G12A AXIN2 81 52 White -0.89 -3.61 0.95 1115.27 1.00 2785 80 51 1 TRUE 0.34
colorectal cancer KRAS_G12A AXIN2 40 87 Race:overall 0.77 -3.73 4.89 1372.60 1.00 1631 35 82 5 TRUE 0.15
non-small cell lung cancer KRAS_G12A AXIN2 81 52 Race:overall -0.86 -5.48 3.66 1483.47 1.00 2785 80 51 1 TRUE 0.15
colorectal cancer KRAS_G12A DOT1L 41 67 White 0.00 -1.96 1.33 1137.80 1.00 1646 39 65 2 FALSE 0.00
non-small cell lung cancer KRAS_G12A DOT1L 81 88 White -0.44 -2.21 0.87 1332.00 1.00 2753 79 86 2 FALSE 0.25
colorectal cancer KRAS_G12A DOT1L 41 67 Race:overall -0.02 -4.29 4.44 1447.81 1.00 1646 39 65 2 FALSE 0.00
non-small cell lung cancer KRAS_G12A DOT1L 81 88 Race:overall -0.38 -5.19 4.45 1508.30 1.00 2753 79 86 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A PTPRS 81 69 White -1.12 -3.84 0.74 1496.00 1.00 2774 80 68 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A PTPRS 81 69 Race:overall -0.95 -5.56 3.85 1419.79 1.00 2774 80 68 1 FALSE 0.17
colorectal cancer KRAS_G12A SMARCA4 41 126 White 0.62 -0.36 1.44 1463.58 1.00 1603 36 121 5 FALSE 0.80
non-small cell lung cancer KRAS_G12A SMARCA4 81 264 White -0.40 -1.38 0.42 1241.14 1.00 2594 76 259 5 FALSE 0.42
colorectal cancer KRAS_G12A SMARCA4 48 159 Race:overall 0.68 -0.43 1.79 1623.39 1.00 1852 41 152 7 FALSE 0.53
non-small cell lung cancer KRAS_G12A SMARCA4 88 310 Race:overall -0.24 -1.75 1.30 1529.95 1.00 3244 82 304 6 FALSE 0.13
colorectal cancer KRAS_G12A PTPRT 40 150 White -0.86 -2.57 0.45 431.08 1.01 1568 38 148 2 FALSE 0.58
non-small cell lung cancer KRAS_G12A PTPRT 83 299 White -0.15 -0.96 0.53 1521.32 1.00 2598 75 291 8 FALSE 0.16
colorectal cancer KRAS_G12A PTPRT 42 162 Race:overall -0.93 -3.08 0.82 952.75 1.01 1686 40 160 2 FALSE 0.46
non-small cell lung cancer KRAS_G12A PTPRT 90 348 Race:overall -0.40 -2.07 0.92 1625.16 1.00 3246 82 340 8 FALSE 0.23
colorectal cancer KRAS_G12A HGF 40 39 White -5.39 -13.87 0.14 183.55 1.00 1665 40 39 0 FALSE 0.65
non-small cell lung cancer KRAS_G12A HGF 81 156 White 0.00 -1.09 0.92 1415.95 1.00 2697 76 151 5 FALSE 0.00
colorectal cancer KRAS_G12A HGF 40 39 Race:overall -4.05 -12.37 3.28 90.40 1.01 1665 40 39 0 FALSE 0.51
non-small cell lung cancer KRAS_G12A HGF 83 173 Race:overall -0.21 -2.81 1.65 1411.01 1.00 2873 78 168 5 FALSE 0.07
colorectal cancer KRAS_G12A BLM 40 50 White -5.26 -14.91 -0.09 1154.18 1.00 1659 40 50 0 TRUE 0.66
colorectal cancer KRAS_G12A BLM 40 50 Race:overall -3.71 -11.80 3.05 852.95 1.00 1659 40 50 0 TRUE 0.52
colorectal cancer KRAS_G12A PIK3CA 45 403 White 0.08 -0.58 0.79 556.11 1.00 1536 35 393 10 TRUE 0.09
non-small cell lung cancer KRAS_G12A PIK3CA 85 189 White -0.01 -0.90 0.83 1094.38 1.00 2749 79 183 6 TRUE 0.00
colorectal cancer KRAS_G12A PIK3CA 54 498 Race:overall 0.07 -0.64 0.84 628.55 1.00 1906 42 486 12 TRUE 0.07
non-small cell lung cancer KRAS_G12A PIK3CA 89 233 Race:overall -0.23 -2.25 1.20 1429.85 1.00 3250 83 227 6 TRUE 0.10
non-small cell lung cancer KRAS_G12A GATA3 81 57 White -1.07 -3.99 0.73 1407.01 1.00 2784 80 56 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A GATA3 81 57 Race:overall -0.91 -5.53 3.87 1585.76 1.00 2784 80 56 1 FALSE 0.16
colorectal cancer KRAS_G12A ESR1 40 61 White -0.80 -3.45 1.10 1154.80 1.00 1643 39 60 1 TRUE 0.30
non-small cell lung cancer KRAS_G12A ESR1 81 45 White -5.12 -14.16 -0.12 1192.78 1.00 2794 81 45 0 TRUE 0.69
colorectal cancer KRAS_G12A ESR1 40 61 Race:overall -0.70 -5.36 4.14 1389.62 1.00 1643 39 60 1 TRUE 0.12
non-small cell lung cancer KRAS_G12A ESR1 81 45 Race:overall -3.74 -10.88 3.09 1188.32 1.00 2794 81 45 0 TRUE 0.54
colorectal cancer KRAS_G12A ALK 44 95 White -1.23 -4.18 0.60 1046.89 1.00 1808 43 94 1 TRUE 0.51
non-small cell lung cancer KRAS_G12A ALK 84 141 White -1.87 -4.84 -0.06 1252.95 1.00 2793 83 140 1 TRUE 0.92
colorectal cancer KRAS_G12A ALK 44 95 Race:overall -0.90 -5.57 4.76 1332.95 1.00 1808 43 94 1 TRUE 0.15
non-small cell lung cancer KRAS_G12A ALK 86 154 Race:overall -1.89 -5.62 1.03 1166.21 1.00 3128 85 153 1 TRUE 0.62
colorectal cancer KRAS_G12A RNF43 40 217 White -2.25 -4.78 -0.52 285.02 1.02 1540 39 216 1 TRUE 1.33
colorectal cancer KRAS_G12A RNF43 47 253 Race:overall -2.26 -4.83 -0.51 265.33 1.02 1806 46 252 1 TRUE 1.31
non-small cell lung cancer KRAS_G12A U2AF1 82 65 White 1.22 0.29 2.06 1306.56 1.01 2778 76 59 6 FALSE 2.11
non-small cell lung cancer KRAS_G12A U2AF1 82 65 Race:overall 1.08 -3.60 5.44 1429.88 1.00 2778 76 59 6 FALSE 0.22
non-small cell lung cancer KRAS_G12A LATS1 81 59 White -0.96 -3.91 0.86 1267.48 1.00 2779 80 58 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A LATS1 81 59 Race:overall -0.85 -5.37 3.77 1481.25 1.00 2779 80 58 1 FALSE 0.15
non-small cell lung cancer KRAS_G12A LATS2 81 45 White -5.33 -15.62 -0.04 1423.48 1.00 2791 81 45 0 FALSE 0.68
non-small cell lung cancer KRAS_G12A LATS2 81 45 Race:overall -3.71 -10.99 3.33 1171.01 1.00 2791 81 45 0 FALSE 0.50
colorectal cancer KRAS_G12A PTEN 44 141 White -0.97 -2.70 0.31 868.39 1.00 1784 42 139 2 TRUE 0.67
non-small cell lung cancer KRAS_G12A PTEN 84 111 White -0.71 -2.41 0.63 1125.53 1.00 2821 82 109 2 TRUE 0.42
colorectal cancer KRAS_G12A PTEN 53 181 Race:overall -1.01 -2.79 0.36 974.16 1.00 2203 51 179 2 TRUE 0.67
non-small cell lung cancer KRAS_G12A PTEN 86 124 Race:overall -0.77 -3.72 1.60 1370.63 1.00 3156 84 122 2 TRUE 0.25
colorectal cancer KRAS_G12A BCOR 40 94 White -1.28 -4.13 0.50 1322.91 1.00 1624 39 93 1 FALSE 0.56
non-small cell lung cancer KRAS_G12A BCOR 81 117 White -0.74 -2.64 0.53 1353.58 1.00 2731 79 115 2 FALSE 0.44
colorectal cancer KRAS_G12A BCOR 40 94 Race:overall -1.15 -5.69 3.39 1393.51 1.00 1624 39 93 1 FALSE 0.22
non-small cell lung cancer KRAS_G12A BCOR 81 117 Race:overall -0.66 -5.31 4.03 1456.58 1.00 2731 79 115 2 FALSE 0.12
colorectal cancer KRAS_G12A CTNNB1 44 124 White -0.34 -1.77 0.74 675.50 1.00 1772 42 122 2 TRUE 0.22
non-small cell lung cancer KRAS_G12A CTNNB1 84 88 White -0.05 -1.47 1.07 1472.54 1.00 2842 81 85 3 TRUE 0.03
colorectal cancer KRAS_G12A CTNNB1 51 152 Race:overall -0.30 -1.82 0.94 697.90 1.00 2070 48 149 3 TRUE 0.18
non-small cell lung cancer KRAS_G12A CTNNB1 88 116 Race:overall -0.25 -2.34 1.40 1345.36 1.00 3358 85 113 3 TRUE 0.10
colorectal cancer KRAS_G12A ARID1A 40 249 White -0.67 -1.74 0.19 841.55 1.01 1531 38 247 2 TRUE 0.75
non-small cell lung cancer KRAS_G12A ARID1A 82 231 White -0.68 -1.82 0.26 1211.41 1.00 2629 78 227 4 TRUE 0.70
colorectal cancer KRAS_G12A ARID1A 49 310 Race:overall -0.63 -1.73 0.29 999.77 1.00 1906 45 306 4 TRUE 0.65
non-small cell lung cancer KRAS_G12A ARID1A 86 271 Race:overall -0.83 -2.82 0.74 1347.75 1.00 3112 82 267 4 TRUE 0.46
colorectal cancer KRAS_G12A PIK3R1 40 95 White -1.29 -4.04 0.52 1078.02 1.00 1623 39 94 1 TRUE 0.57
non-small cell lung cancer KRAS_G12A PIK3R1 81 41 White -5.18 -14.47 0.09 896.54 1.00 2795 81 41 0 TRUE 0.71
colorectal cancer KRAS_G12A PIK3R1 40 95 Race:overall -1.08 -5.38 3.42 1240.63 1.00 1623 39 94 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A PIK3R1 81 41 Race:overall -3.83 -11.44 3.06 1020.20 1.00 2795 81 41 0 TRUE 0.52
colorectal cancer KRAS_G12A IKZF1 40 69 White -5.51 -14.63 -0.22 891.02 1.00 1636 40 69 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A IKZF1 81 67 White -0.13 -2.15 1.19 450.77 1.01 2772 79 65 2 TRUE 0.06
colorectal cancer KRAS_G12A IKZF1 40 69 Race:overall -4.22 -11.11 2.19 428.83 1.00 1636 40 69 0 TRUE 0.64
non-small cell lung cancer KRAS_G12A IKZF1 81 67 Race:overall -0.18 -4.84 4.44 1554.40 1.00 2772 79 65 2 TRUE 0.03
colorectal cancer KRAS_G12A TERT 40 75 White -1.03 -3.73 0.78 1378.74 1.00 1635 39 74 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A TERT 81 135 White -0.07 -1.29 0.93 1458.02 1.00 2711 77 131 4 TRUE 0.05
colorectal cancer KRAS_G12A TERT 40 75 Race:overall -0.85 -5.29 3.92 1387.75 1.00 1635 39 74 1 TRUE 0.15
non-small cell lung cancer KRAS_G12A TERT 83 146 Race:overall -0.23 -3.06 2.11 1440.82 1.00 3029 79 142 4 TRUE 0.06
colorectal cancer KRAS_G12A FAT1 40 180 White 0.12 -0.81 0.99 1146.97 1.00 1575 36 176 4 FALSE 0.10
non-small cell lung cancer KRAS_G12A FAT1 81 261 White -0.54 -1.57 0.33 1410.59 1.00 2609 76 256 5 FALSE 0.58
colorectal cancer KRAS_G12A FAT1 50 225 Race:overall 0.16 -0.89 1.17 920.53 1.00 1973 44 219 6 FALSE 0.12
non-small cell lung cancer KRAS_G12A FAT1 88 301 Race:overall -0.70 -2.31 0.66 1526.68 1.00 3262 83 296 5 FALSE 0.44
colorectal cancer KRAS_G12A FGFR4 40 39 White -0.41 -3.22 1.60 1386.47 1.00 1666 39 38 1 TRUE 0.13
colorectal cancer KRAS_G12A FGFR4 40 39 Race:overall -0.30 -4.98 4.71 1430.16 1.00 1666 39 38 1 TRUE 0.05
colorectal cancer KRAS_G12A CIC 41 111 White 0.02 -1.33 1.12 1409.47 1.00 1613 38 108 3 TRUE 0.01
non-small cell lung cancer KRAS_G12A CIC 81 81 White 0.12 -1.24 1.16 1210.57 1.00 2770 78 78 3 TRUE 0.07
colorectal cancer KRAS_G12A CIC 41 111 Race:overall -0.02 -4.55 4.60 1717.60 1.00 1613 38 108 3 TRUE 0.00
non-small cell lung cancer KRAS_G12A CIC 81 81 Race:overall 0.04 -4.96 4.60 1532.23 1.00 2770 78 78 3 TRUE 0.01
colorectal cancer KRAS_G12A KDM6A 40 49 White -0.62 -3.68 1.27 1293.77 1.00 1657 39 48 1 FALSE 0.21
non-small cell lung cancer KRAS_G12A KDM6A 82 45 White 0.74 -0.71 1.85 991.05 1.00 2795 79 42 3 FALSE 0.60
colorectal cancer KRAS_G12A KDM6A 40 49 Race:overall -0.51 -5.18 4.51 1123.75 1.00 1657 39 48 1 FALSE 0.08
non-small cell lung cancer KRAS_G12A KDM6A 82 45 Race:overall 0.75 -3.94 5.62 1495.14 1.00 2795 79 42 3 FALSE 0.13
colorectal cancer KRAS_G12A NCOR1 40 108 White -0.18 -1.56 0.99 97.11 1.02 1620 37 105 3 FALSE 0.11
non-small cell lung cancer KRAS_G12A NCOR1 81 82 White 0.79 -0.28 1.70 994.55 1.00 2767 76 77 5 FALSE 0.93
colorectal cancer KRAS_G12A NCOR1 43 120 Race:overall -0.25 -2.06 1.32 186.02 1.02 1757 40 117 3 FALSE 0.11
non-small cell lung cancer KRAS_G12A NCOR1 81 82 Race:overall 0.67 -4.14 4.96 1497.76 1.00 2767 76 77 5 FALSE 0.13
colorectal cancer KRAS_G12A POLE 40 115 White -0.13 -1.57 1.00 1253.44 1.00 1609 37 112 3 TRUE 0.07
non-small cell lung cancer KRAS_G12A POLE 81 112 White -0.18 -1.59 0.85 860.50 1.00 2734 78 109 3 TRUE 0.11
colorectal cancer KRAS_G12A POLE 43 128 Race:overall -0.24 -2.45 1.42 1350.10 1.00 1748 40 125 3 TRUE 0.09
non-small cell lung cancer KRAS_G12A POLE 81 112 Race:overall -0.19 -4.75 3.94 1510.90 1.00 2734 78 109 3 TRUE 0.03
non-small cell lung cancer KRAS_G12A CUL3 81 64 White -1.02 -3.78 0.75 1250.16 1.00 2780 80 63 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A CUL3 81 64 Race:overall -0.86 -5.78 4.15 1563.98 1.00 2780 80 63 1 FALSE 0.15
colorectal cancer KRAS_G12A ABL1 44 59 White -4.99 -14.85 -0.09 933.05 1.01 1837 44 59 0 TRUE 0.61
colorectal cancer KRAS_G12A ABL1 44 59 Race:overall -3.67 -11.20 2.61 1336.77 1.00 1837 44 59 0 TRUE 0.53
colorectal cancer KRAS_G12A FOXP1 40 56 White -5.27 -15.57 -0.18 755.61 1.00 1650 40 56 0 FALSE 0.65
colorectal cancer KRAS_G12A FOXP1 40 56 Race:overall -3.60 -10.99 3.28 1256.99 1.00 1650 40 56 0 FALSE 0.49
non-small cell lung cancer KRAS_G12A NOTCH2 81 98 White -5.88 -16.55 -0.82 1291.39 1.00 2748 81 98 0 TRUE 0.78
non-small cell lung cancer KRAS_G12A NOTCH2 81 98 Race:overall -4.22 -11.71 2.46 1129.47 1.00 2748 81 98 0 TRUE 0.66
non-small cell lung cancer KRAS_G12A DDR2 81 82 White -5.62 -15.00 -0.63 997.00 1.00 2754 81 82 0 TRUE 0.77
non-small cell lung cancer KRAS_G12A DDR2 81 82 Race:overall -4.18 -11.87 2.60 868.91 1.00 2754 81 82 0 TRUE 0.64
colorectal cancer KRAS_G12A TGFBR2 40 93 White -5.75 -15.67 -0.51 903.46 1.00 1614 40 93 0 TRUE 0.69
non-small cell lung cancer KRAS_G12A TGFBR2 81 48 White -5.17 -15.01 0.03 988.85 1.00 2792 81 48 0 TRUE 0.64
colorectal cancer KRAS_G12A TGFBR2 40 93 Race:overall -4.10 -11.47 2.59 1212.88 1.00 1614 40 93 0 TRUE 0.62
non-small cell lung cancer KRAS_G12A TGFBR2 81 48 Race:overall -3.72 -11.55 3.15 1223.08 1.00 2792 81 48 0 TRUE 0.52
colorectal cancer KRAS_G12A SMO 44 57 White -5.20 -14.79 0.10 1087.63 1.00 1836 44 57 0 TRUE 0.60
non-small cell lung cancer KRAS_G12A SMO 84 64 White -0.13 -1.99 1.21 1368.77 1.00 2865 82 62 2 TRUE 0.06
colorectal cancer KRAS_G12A SMO 44 57 Race:overall -3.55 -11.24 3.55 1332.22 1.00 1836 44 57 0 TRUE 0.48
non-small cell lung cancer KRAS_G12A SMO 84 64 Race:overall -0.13 -4.57 4.45 1315.54 1.00 2865 82 62 2 TRUE 0.02
colorectal cancer KRAS_G12A KMT2A 40 122 White -5.69 -14.89 -0.86 1376.30 1.00 1601 40 122 0 FALSE 0.90
non-small cell lung cancer KRAS_G12A KMT2A 81 99 White -1.53 -4.63 0.25 1355.93 1.00 2744 80 98 1 FALSE 0.69
colorectal cancer KRAS_G12A KMT2A 40 122 Race:overall -4.29 -11.46 2.61 1092.87 1.00 1601 40 122 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A KMT2A 81 99 Race:overall -1.24 -5.73 3.89 1392.43 1.00 2744 80 98 1 FALSE 0.23
colorectal cancer KRAS_G12A JAK3 44 51 White -0.63 -3.46 1.29 1334.15 1.00 1842 43 50 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A JAK3 84 73 White -0.26 -2.15 0.96 410.38 1.01 2856 82 71 2 TRUE 0.13
colorectal cancer KRAS_G12A JAK3 44 51 Race:overall -0.54 -5.08 3.87 1478.25 1.00 1842 43 50 1 TRUE 0.09
non-small cell lung cancer KRAS_G12A JAK3 84 73 Race:overall -0.27 -4.92 3.87 1512.11 1.00 2856 82 71 2 TRUE 0.05
non-small cell lung cancer KRAS_G12A PAK7 82 107 White -0.25 -1.72 0.86 1324.65 1.00 2738 79 104 3 FALSE 0.16
non-small cell lung cancer KRAS_G12A PAK7 85 121 Race:overall -0.44 -3.07 1.53 1563.51 1.00 2898 82 118 3 FALSE 0.16
non-small cell lung cancer KRAS_G12A STAG2 81 85 White 0.94 -0.08 1.77 1278.25 1.00 2762 75 79 6 TRUE 1.37
non-small cell lung cancer KRAS_G12A STAG2 81 85 Race:overall 0.77 -4.27 5.34 1462.89 1.00 2762 75 79 6 TRUE 0.14
colorectal cancer KRAS_G12A BRCA2 42 149 White -0.51 -1.86 0.65 928.26 1.00 1598 39 146 3 TRUE 0.36
non-small cell lung cancer KRAS_G12A BRCA2 81 110 White 0.14 -1.05 1.05 1455.05 1.00 2740 77 106 4 TRUE 0.10
colorectal cancer KRAS_G12A BRCA2 49 180 Race:overall -0.57 -2.15 0.70 879.19 1.00 1873 46 177 3 TRUE 0.36
non-small cell lung cancer KRAS_G12A BRCA2 83 122 Race:overall -0.04 -3.13 2.21 1427.63 1.00 3057 79 118 4 TRUE 0.01
colorectal cancer KRAS_G12A NOTCH3 40 154 White 0.02 -1.14 0.96 382.76 1.01 1583 36 150 4 TRUE 0.02
non-small cell lung cancer KRAS_G12A NOTCH3 81 106 White -0.16 -1.61 0.99 1190.54 1.00 2741 78 103 3 TRUE 0.09
colorectal cancer KRAS_G12A NOTCH3 49 197 Race:overall 0.02 -1.14 0.97 409.32 1.01 1968 44 192 5 TRUE 0.01
non-small cell lung cancer KRAS_G12A NOTCH3 81 106 Race:overall -0.08 -4.71 4.44 1286.00 1.00 2741 78 103 3 TRUE 0.01
non-small cell lung cancer KRAS_G12A NOTCH4 81 117 White -0.72 -2.46 0.62 1407.91 1.00 2727 79 115 2 TRUE 0.45
non-small cell lung cancer KRAS_G12A NOTCH4 81 117 Race:overall -0.58 -4.88 3.95 1492.22 1.00 2727 79 115 2 TRUE 0.10
colorectal cancer KRAS_G12A FGFR3 44 45 White -0.45 -3.13 1.30 1180.12 1.00 1847 43 44 1 TRUE 0.16
colorectal cancer KRAS_G12A FGFR3 44 45 Race:overall -0.40 -5.00 4.30 1243.53 1.00 1847 43 44 1 TRUE 0.07
non-small cell lung cancer KRAS_G12A MAP3K13 81 42 White -0.56 -3.35 1.26 914.47 1.00 2796 80 41 1 FALSE 0.20
non-small cell lung cancer KRAS_G12A MAP3K13 81 42 Race:overall -0.46 -5.05 4.21 1325.76 1.00 2796 80 41 1 FALSE 0.08
colorectal cancer KRAS_G12A IGF1R 40 69 White -5.50 -14.35 -0.19 1117.82 1.00 1642 40 69 0 TRUE 0.66
non-small cell lung cancer KRAS_G12A IGF1R 81 39 White -5.26 -14.74 -0.02 845.08 1.00 2797 81 39 0 TRUE 0.70
colorectal cancer KRAS_G12A IGF1R 40 69 Race:overall -4.14 -11.20 2.50 447.11 1.01 1642 40 69 0 TRUE 0.63
non-small cell lung cancer KRAS_G12A IGF1R 81 39 Race:overall -4.00 -11.61 3.10 747.09 1.00 2797 81 39 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A KEAP1 82 461 White 0.18 -0.40 0.72 1294.66 1.00 2409 66 445 16 FALSE 0.28
non-small cell lung cancer KRAS_G12A KEAP1 89 532 Race:overall -0.12 -1.53 0.95 1329.73 1.00 3032 73 516 16 FALSE 0.07
colorectal cancer KRAS_G12A KDM5C 40 51 White -4.84 -12.33 -0.05 1396.65 1.00 1656 40 51 0 FALSE 0.87
non-small cell lung cancer KRAS_G12A KDM5C 81 87 White -0.44 -2.60 0.90 1063.25 1.00 2755 79 85 2 FALSE 0.22
colorectal cancer KRAS_G12A KDM5C 44 63 Race:overall -4.64 -11.59 0.17 1306.12 1.00 1793 44 63 0 FALSE 0.87
non-small cell lung cancer KRAS_G12A KDM5C 81 87 Race:overall -0.43 -5.14 4.17 1474.85 1.00 2755 79 85 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A CDKN2A 85 218 White -0.18 -1.08 0.60 1491.04 1.00 2728 79 212 6 TRUE 0.16
non-small cell lung cancer KRAS_G12A CDKN2A 92 271 Race:overall -0.43 -2.08 0.81 1381.40 1.00 3396 86 265 6 TRUE 0.25
colorectal cancer KRAS_G12A EPHB1 40 65 White -5.24 -14.91 -0.34 1359.98 1.00 1638 40 65 0 FALSE 0.69
non-small cell lung cancer KRAS_G12A EPHB1 82 135 White 0.16 -0.94 1.07 1060.00 1.00 2719 77 130 5 FALSE 0.13
colorectal cancer KRAS_G12A EPHB1 40 65 Race:overall -3.84 -11.77 3.09 1369.38 1.00 1638 40 65 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A EPHB1 84 146 Race:overall 0.01 -2.10 1.68 1386.24 1.00 2900 79 141 5 FALSE 0.00
colorectal cancer KRAS_G12A IRS2 40 71 White -1.04 -3.97 0.77 1029.81 1.00 1638 39 70 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A IRS2 81 68 White -5.43 -15.12 -0.49 1400.90 1.00 2770 81 68 0 FALSE 0.78
colorectal cancer KRAS_G12A IRS2 40 71 Race:overall -0.88 -5.65 4.07 1084.12 1.00 1638 39 70 1 FALSE 0.15
non-small cell lung cancer KRAS_G12A IRS2 81 68 Race:overall -3.96 -11.80 3.04 1023.29 1.00 2770 81 68 0 FALSE 0.55
colorectal cancer KRAS_G12A FANCA 40 51 White -5.31 -14.94 -0.04 1401.60 1.00 1653 40 51 0 TRUE 0.62
non-small cell lung cancer KRAS_G12A FANCA 81 59 White -5.53 -14.57 -0.36 1232.40 1.00 2779 81 59 0 TRUE 0.69
colorectal cancer KRAS_G12A FANCA 40 51 Race:overall -3.78 -11.32 3.46 1072.35 1.00 1653 40 51 0 TRUE 0.56
non-small cell lung cancer KRAS_G12A FANCA 81 59 Race:overall -3.94 -11.30 3.20 1394.29 1.00 2779 81 59 0 TRUE 0.57
non-small cell lung cancer KRAS_G12A IL7R 81 69 White -0.20 -2.01 1.11 1228.89 1.00 2776 79 67 2 FALSE 0.09
non-small cell lung cancer KRAS_G12A IL7R 81 69 Race:overall -0.26 -4.73 4.23 1405.78 1.00 2776 79 67 2 FALSE 0.04
colorectal cancer KRAS_G12A ERBB3 40 94 White -1.43 -4.51 0.70 341.95 1.00 1620 39 93 1 TRUE 0.54
colorectal cancer KRAS_G12A ERBB3 43 105 Race:overall -1.52 -4.88 1.03 357.03 1.00 1757 42 104 1 TRUE 0.51
colorectal cancer KRAS_G12A SMAD4 44 274 White -0.17 -1.06 0.60 954.76 1.00 1643 38 268 6 TRUE 0.16
non-small cell lung cancer KRAS_G12A SMAD4 84 89 White -1.49 -4.33 0.37 1039.00 1.00 2838 83 88 1 TRUE 0.66
colorectal cancer KRAS_G12A SMAD4 53 348 Race:overall -0.19 -1.11 0.66 1016.16 1.00 2027 46 341 7 TRUE 0.17
non-small cell lung cancer KRAS_G12A SMAD4 86 100 Race:overall -1.47 -4.97 1.26 1176.64 1.00 3176 85 99 1 TRUE 0.45
colorectal cancer KRAS_G12A ATM 46 176 White 0.13 -0.80 0.93 985.77 1.01 1750 40 170 6 TRUE 0.12
non-small cell lung cancer KRAS_G12A ATM 87 245 White 0.94 0.38 1.47 1349.86 1.00 2719 72 230 15 TRUE 3.26
colorectal cancer KRAS_G12A ATM 55 227 Race:overall 0.06 -0.92 0.92 1106.87 1.01 2169 49 221 6 TRUE 0.05
non-small cell lung cancer KRAS_G12A ATM 95 284 Race:overall 0.98 -0.24 2.11 1525.56 1.00 3406 78 267 17 TRUE 1.05
colorectal cancer KRAS_G12A RB1 44 57 White -5.15 -15.31 -0.16 876.35 1.00 1841 44 57 0 TRUE 0.63
non-small cell lung cancer KRAS_G12A RB1 84 164 White -1.23 -3.04 0.09 1487.62 1.00 2768 82 162 2 TRUE 0.89
colorectal cancer KRAS_G12A RB1 44 57 Race:overall -3.71 -11.48 3.03 977.58 1.00 1841 44 57 0 TRUE 0.55
non-small cell lung cancer KRAS_G12A RB1 91 220 Race:overall -1.30 -3.34 0.30 1534.16 1.00 3432 89 218 2 TRUE 0.81
colorectal cancer KRAS_G12A KMT2D 40 298 White -0.98 -2.20 -0.03 700.57 1.00 1522 38 296 2 FALSE 1.20
non-small cell lung cancer KRAS_G12A KMT2D 81 266 White -0.51 -1.54 0.31 1233.23 1.00 2614 77 262 4 FALSE 0.56
colorectal cancer KRAS_G12A KMT2D 50 381 Race:overall -0.92 -2.15 0.09 952.30 1.00 1891 46 377 4 FALSE 1.05
non-small cell lung cancer KRAS_G12A KMT2D 89 322 Race:overall -0.14 -1.51 1.26 1407.89 1.00 3256 83 316 6 FALSE 0.07
colorectal cancer KRAS_G12A TSC2 41 91 White 0.19 -1.29 1.29 434.16 1.00 1629 38 88 3 TRUE 0.11
non-small cell lung cancer KRAS_G12A TSC2 82 63 White 0.79 -0.45 1.76 469.35 1.00 2779 78 59 4 TRUE 0.77
colorectal cancer KRAS_G12A TSC2 41 91 Race:overall 0.21 -4.33 4.79 1416.03 1.00 1629 38 88 3 TRUE 0.03
non-small cell lung cancer KRAS_G12A TSC2 82 63 Race:overall 0.59 -3.79 4.83 1456.89 1.00 2779 78 59 4 TRUE 0.12
colorectal cancer KRAS_G12A APC 59 1977 White 0.18 -0.35 0.75 1313.24 1.00 647 12 1930 47 TRUE 0.29
non-small cell lung cancer KRAS_G12A APC 84 125 White 0.18 -0.88 1.02 1165.39 1.00 2811 80 121 4 TRUE 0.15
colorectal cancer KRAS_G12A APC 73 2530 Race:overall 0.04 -0.77 0.80 1368.19 1.00 809 16 2473 57 TRUE 0.03
non-small cell lung cancer KRAS_G12A APC 88 149 Race:overall 0.38 -1.35 1.98 1390.52 1.00 3333 83 144 5 TRUE 0.20
colorectal cancer KRAS_G12A ERBB2 44 84 White -5.80 -15.58 -0.43 1381.99 1.00 1811 44 84 0 TRUE 0.68
non-small cell lung cancer KRAS_G12A ERBB2 84 101 White -5.05 -11.79 -0.77 915.92 1.00 2828 84 101 0 TRUE 1.05
colorectal cancer KRAS_G12A ERBB2 44 84 Race:overall -4.16 -11.85 2.52 1373.53 1.00 1811 44 84 0 TRUE 0.62
non-small cell lung cancer KRAS_G12A ERBB2 86 114 Race:overall -4.76 -11.34 0.06 1067.60 1.00 3162 86 114 0 TRUE 0.96
colorectal cancer KRAS_G12A JAK1 40 58 White 0.23 -1.52 1.52 869.00 1.01 1653 38 56 2 TRUE 0.11
non-small cell lung cancer KRAS_G12A JAK1 81 41 White 0.35 -1.26 1.65 984.48 1.00 2798 79 39 2 TRUE 0.19
colorectal cancer KRAS_G12A JAK1 40 58 Race:overall 0.24 -4.32 4.87 1262.19 1.00 1653 38 56 2 TRUE 0.04
non-small cell lung cancer KRAS_G12A JAK1 81 41 Race:overall 0.26 -4.35 4.53 1518.74 1.00 2798 79 39 2 TRUE 0.04
colorectal cancer KRAS_G12A ARID2 40 89 White -0.26 -2.07 1.07 1149.20 1.00 1624 38 87 2 FALSE 0.13
non-small cell lung cancer KRAS_G12A ARID2 81 145 White 0.11 -0.95 1.00 1365.44 1.00 2706 76 140 5 FALSE 0.08
colorectal cancer KRAS_G12A ARID2 40 89 Race:overall -0.25 -4.89 4.45 1533.40 1.00 1624 38 87 2 FALSE 0.04
non-small cell lung cancer KRAS_G12A ARID2 83 162 Race:overall -0.13 -2.65 1.88 1536.10 1.00 3019 78 157 5 FALSE 0.04
non-small cell lung cancer KRAS_G12A SOX17 81 51 White -0.82 -3.60 0.97 1437.41 1.00 2787 80 50 1 FALSE 0.32
non-small cell lung cancer KRAS_G12A SOX17 81 51 Race:overall -0.62 -5.24 4.04 1485.99 1.00 2787 80 50 1 FALSE 0.10
colorectal cancer KRAS_G12A MTOR 40 111 White -1.62 -4.55 0.21 931.93 1.00 1608 39 110 1 TRUE 0.74
non-small cell lung cancer KRAS_G12A MTOR 81 92 White -1.40 -4.13 0.42 1197.50 1.00 2747 80 91 1 TRUE 0.63
colorectal cancer KRAS_G12A MTOR 44 123 Race:overall -1.67 -4.60 0.39 957.46 1.00 1742 43 122 1 TRUE 0.71
non-small cell lung cancer KRAS_G12A MTOR 81 92 Race:overall -1.24 -6.03 3.71 1325.22 1.00 2747 80 91 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A RFWD2 81 50 White 0.13 -1.68 1.49 1456.97 1.00 2788 79 48 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A RFWD2 81 50 Race:overall 0.14 -4.43 4.87 1483.31 1.00 2788 79 48 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A IRS1 81 58 White -5.52 -14.93 -0.48 1070.07 1.00 2780 81 58 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A IRS1 81 58 Race:overall -3.98 -12.19 2.89 1268.17 1.00 2780 81 58 0 FALSE 0.56
colorectal cancer KRAS_G12A NOTCH1 45 133 White -0.43 -1.72 0.64 149.89 1.02 1787 42 130 3 TRUE 0.31
non-small cell lung cancer KRAS_G12A NOTCH1 84 108 White 0.40 -0.71 1.28 1169.70 1.00 2828 79 103 5 TRUE 0.37
colorectal cancer KRAS_G12A NOTCH1 54 170 Race:overall -0.45 -1.73 0.68 146.12 1.02 2211 51 167 3 TRUE 0.32
non-small cell lung cancer KRAS_G12A NOTCH1 86 119 Race:overall 0.15 -2.50 2.14 1405.34 1.00 3014 81 114 5 TRUE 0.05
colorectal cancer KRAS_G12A NTRK1 40 46 White 0.96 -0.45 2.16 1334.52 1.00 1660 37 43 3 TRUE 0.83
non-small cell lung cancer KRAS_G12A NTRK1 81 75 White 0.56 -0.53 1.54 1272.52 1.00 2767 77 71 4 TRUE 0.53
colorectal cancer KRAS_G12A NTRK1 40 46 Race:overall 0.78 -3.81 5.25 1426.99 1.00 1660 37 43 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A NTRK1 81 75 Race:overall 0.50 -4.06 4.94 1338.99 1.00 2767 77 71 4 TRUE 0.09
non-small cell lung cancer KRAS_G12A INPP4A 81 45 White -0.70 -3.48 1.10 1457.17 1.00 2793 80 44 1 FALSE 0.26
non-small cell lung cancer KRAS_G12A INPP4A 81 45 Race:overall -0.51 -5.11 4.42 1533.59 1.00 2793 80 44 1 FALSE 0.08
colorectal cancer KRAS_G12A SETD2 40 89 White -1.22 -4.04 0.55 1460.87 1.00 1627 39 88 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A SETD2 82 185 White 0.07 -0.92 0.85 1245.81 1.00 2685 76 179 6 FALSE 0.06
colorectal cancer KRAS_G12A SETD2 40 89 Race:overall -1.04 -5.66 3.93 1348.90 1.00 1627 39 88 1 FALSE 0.19
non-small cell lung cancer KRAS_G12A SETD2 84 205 Race:overall -0.18 -2.94 1.94 1369.96 1.00 2996 78 199 6 FALSE 0.06
colorectal cancer KRAS_G12A PBRM1 40 77 White -5.81 -15.00 -0.56 499.75 1.00 1635 40 77 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A PBRM1 81 95 White 0.03 -1.29 1.08 640.30 1.00 2756 78 92 3 TRUE 0.02
colorectal cancer KRAS_G12A PBRM1 40 77 Race:overall -4.26 -11.96 3.04 231.23 1.01 1635 40 77 0 TRUE 0.57
non-small cell lung cancer KRAS_G12A PBRM1 81 95 Race:overall 0.11 -4.37 4.35 1342.50 1.00 2756 78 92 3 TRUE 0.02
colorectal cancer KRAS_G12A EPHA3 40 81 White 0.10 -1.38 1.26 1472.20 1.00 1628 38 79 2 FALSE 0.05
non-small cell lung cancer KRAS_G12A EPHA3 82 199 White 0.25 -0.58 0.97 1382.25 1.00 2661 74 191 8 FALSE 0.28
colorectal cancer KRAS_G12A EPHA3 45 104 Race:overall 0.18 -1.40 1.50 1386.52 1.00 1884 42 101 3 FALSE 0.09
non-small cell lung cancer KRAS_G12A EPHA3 87 231 Race:overall 0.14 -1.02 1.12 1452.55 1.00 2996 79 223 8 FALSE 0.09
colorectal cancer KRAS_G12A KIT 44 38 White -4.90 -13.82 0.20 1229.87 1.00 1851 44 38 0 TRUE 0.67
non-small cell lung cancer KRAS_G12A KIT 84 69 White -5.68 -16.32 -0.41 783.14 1.01 2856 84 69 0 TRUE 0.69
colorectal cancer KRAS_G12A KIT 44 38 Race:overall -3.62 -11.19 3.12 1236.17 1.00 1851 44 38 0 TRUE 0.49
non-small cell lung cancer KRAS_G12A KIT 84 69 Race:overall -4.16 -12.02 2.81 759.63 1.00 2856 84 69 0 TRUE 0.58
colorectal cancer KRAS_G12A KDR 44 55 White -0.65 -3.33 1.23 1448.43 1.00 1839 43 54 1 TRUE 0.24
non-small cell lung cancer KRAS_G12A KDR 84 121 White 0.24 -0.83 1.13 365.92 1.01 2814 79 116 5 TRUE 0.21
colorectal cancer KRAS_G12A KDR 44 55 Race:overall -0.49 -5.34 4.38 1782.23 1.00 1839 43 54 1 TRUE 0.08
non-small cell lung cancer KRAS_G12A KDR 86 132 Race:overall 0.10 -1.98 1.82 1146.44 1.00 3001 81 127 5 TRUE 0.04
colorectal cancer KRAS_G12A RICTOR 40 60 White -0.84 -3.87 1.02 681.65 1.00 1651 39 59 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A RICTOR 81 58 White -0.99 -3.63 0.82 1521.71 1.00 2782 80 57 1 FALSE 0.40
colorectal cancer KRAS_G12A RICTOR 40 60 Race:overall -0.76 -5.43 3.57 1239.48 1.00 1651 39 59 1 FALSE 0.14
non-small cell lung cancer KRAS_G12A RICTOR 81 58 Race:overall -0.84 -6.01 3.92 1550.40 1.00 2782 80 57 1 FALSE 0.14
colorectal cancer KRAS_G12A RAD50 40 42 White -0.39 -3.36 1.33 295.14 1.02 1665 39 41 1 FALSE 0.12
colorectal cancer KRAS_G12A RAD50 40 42 Race:overall -0.28 -4.91 4.15 1241.59 1.00 1665 39 41 1 FALSE 0.05
colorectal cancer KRAS_G12A CSF1R 45 41 White 0.51 -1.38 1.88 1474.29 1.00 1853 43 39 2 TRUE 0.27
non-small cell lung cancer KRAS_G12A CSF1R 84 59 White -0.06 -1.81 1.25 1332.77 1.00 2870 82 57 2 TRUE 0.03
colorectal cancer KRAS_G12A CSF1R 45 41 Race:overall 0.50 -4.30 5.33 1408.08 1.00 1853 43 39 2 TRUE 0.08
non-small cell lung cancer KRAS_G12A CSF1R 84 59 Race:overall -0.01 -4.68 4.58 1518.33 1.00 2870 82 57 2 TRUE 0.00
non-small cell lung cancer KRAS_G12A PARK2 81 59 White -1.00 -3.89 0.81 1572.25 1.00 2778 80 58 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A PARK2 81 59 Race:overall -0.82 -4.94 4.20 1455.92 1.00 2778 80 58 1 FALSE 0.14
non-small cell lung cancer KRAS_G12A NTRK2 81 56 White 0.54 -0.92 1.65 1361.71 1.00 2786 78 53 3 FALSE 0.38
non-small cell lung cancer KRAS_G12A NTRK2 81 56 Race:overall 0.48 -4.39 5.14 1422.88 1.00 2786 78 53 3 FALSE 0.08
colorectal cancer KRAS_G12A PTCH1 40 115 White -1.44 -4.22 0.34 1400.52 1.00 1611 39 114 1 TRUE 0.67
non-small cell lung cancer KRAS_G12A PTCH1 81 46 White -5.42 -15.29 -0.24 984.69 1.00 2790 81 46 0 TRUE 0.65
colorectal cancer KRAS_G12A PTCH1 40 115 Race:overall -1.17 -5.39 3.59 1505.26 1.00 1611 39 114 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A PTCH1 81 46 Race:overall -3.84 -11.30 2.94 1357.27 1.00 2790 81 46 0 TRUE 0.52
non-small cell lung cancer KRAS_G12A TET1 81 101 White -0.11 -1.52 1.01 1508.94 1.00 2744 78 98 3 FALSE 0.07
non-small cell lung cancer KRAS_G12A TET1 81 101 Race:overall -0.10 -4.64 4.14 1437.98 1.00 2744 78 98 3 FALSE 0.02
colorectal cancer KRAS_G12A FGFR2 44 38 White -0.35 -3.31 1.53 1125.08 1.00 1852 43 37 1 TRUE 0.11
colorectal cancer KRAS_G12A FGFR2 44 38 Race:overall -0.32 -5.34 4.91 1530.88 1.00 1852 43 37 1 TRUE 0.05
colorectal cancer KRAS_G12A TBX3 40 57 White -1.90 -4.11 0.93 1.93 2.02 1653 39 56 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A TBX3 81 114 White -0.16 -1.60 1.22 129.49 1.02 2734 78 111 3 FALSE 0.09
colorectal cancer KRAS_G12A TBX3 40 57 Race:overall -1.82 -4.60 3.36 2.93 1.41 1653 39 56 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A TBX3 81 114 Race:overall -0.12 -4.91 4.12 1206.61 1.00 2734 78 111 3 FALSE 0.02
colorectal cancer KRAS_G12A HNF1A 44 40 White -5.25 -15.28 0.25 1241.23 1.00 1848 44 40 0 TRUE 0.67
colorectal cancer KRAS_G12A HNF1A 44 40 Race:overall -3.84 -11.70 3.68 990.06 1.00 1848 44 40 0 TRUE 0.50
colorectal cancer KRAS_G12A DICER1 40 49 White -4.60 -11.65 -0.20 1318.26 1.00 1657 40 49 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A DICER1 81 69 White -5.54 -15.13 -0.38 955.24 1.01 2773 81 69 0 TRUE 0.65
colorectal cancer KRAS_G12A DICER1 43 61 Race:overall -4.39 -11.28 0.22 1290.56 1.00 1795 43 61 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A DICER1 81 69 Race:overall -4.04 -11.34 2.94 1124.08 1.00 2773 81 69 0 TRUE 0.60
colorectal cancer KRAS_G12A SMAD3 43 84 White 0.74 -0.30 1.72 246.58 1.01 1631 38 79 5 TRUE 0.78
colorectal cancer KRAS_G12A SMAD3 46 98 Race:overall 0.43 -2.04 2.08 1376.16 1.00 1765 41 93 5 TRUE 0.17
colorectal cancer KRAS_G12A NTRK3 40 60 White -0.88 -3.80 1.05 1160.47 1.00 1648 39 59 1 FALSE 0.32
non-small cell lung cancer KRAS_G12A NTRK3 83 171 White 0.17 -0.83 0.97 1161.98 1.00 2691 77 165 6 FALSE 0.15
colorectal cancer KRAS_G12A NTRK3 40 60 Race:overall -0.72 -5.56 4.21 1493.47 1.00 1648 39 59 1 FALSE 0.12
non-small cell lung cancer KRAS_G12A NTRK3 85 187 Race:overall -0.05 -2.65 2.03 1297.14 1.00 3003 79 181 6 FALSE 0.01
colorectal cancer KRAS_G12A AXIN1 40 57 White -5.25 -15.01 -0.05 1379.20 1.00 1650 40 57 0 FALSE 0.56
colorectal cancer KRAS_G12A AXIN1 40 57 Race:overall -3.71 -11.40 3.31 1423.90 1.00 1650 40 57 0 FALSE 0.50
colorectal cancer KRAS_G12A GRIN2A 41 107 White -0.58 -2.40 0.81 985.49 1.00 1604 39 105 2 FALSE 0.32
non-small cell lung cancer KRAS_G12A GRIN2A 81 171 White -2.06 -4.79 -0.26 1039.47 1.00 2677 80 170 1 FALSE 1.15
colorectal cancer KRAS_G12A GRIN2A 44 118 Race:overall -0.66 -2.85 1.07 1182.65 1.00 1742 42 116 2 FALSE 0.28
non-small cell lung cancer KRAS_G12A GRIN2A 81 171 Race:overall -1.80 -6.16 3.46 1447.13 1.00 2677 80 170 1 FALSE 0.35
colorectal cancer KRAS_G12A PALB2 40 44 White -5.10 -14.15 0.20 1286.06 1.00 1659 40 44 0 TRUE 0.68
non-small cell lung cancer KRAS_G12A PALB2 81 47 White -0.82 -3.58 1.09 1437.67 1.00 2792 80 46 1 TRUE 0.31
colorectal cancer KRAS_G12A PALB2 40 44 Race:overall -3.80 -11.30 2.82 1116.16 1.00 1659 40 44 0 TRUE 0.55
non-small cell lung cancer KRAS_G12A PALB2 81 47 Race:overall -0.76 -5.45 4.10 1262.76 1.00 2792 80 46 1 TRUE 0.13
colorectal cancer KRAS_G12A CTCF 40 71 White -5.44 -15.60 -0.36 1111.40 1.00 1640 40 71 0 FALSE 0.65
colorectal cancer KRAS_G12A CTCF 40 71 Race:overall -3.90 -11.22 3.24 1186.56 1.00 1640 40 71 0 FALSE 0.57
colorectal cancer KRAS_G12A CDH1 44 43 White -0.55 -3.57 1.32 1489.74 1.00 1852 43 42 1 TRUE 0.18
colorectal cancer KRAS_G12A CDH1 44 43 Race:overall -0.46 -4.73 4.42 1450.62 1.00 1852 43 42 1 TRUE 0.08
colorectal cancer KRAS_G12A CDK12 41 76 White -0.07 -1.90 1.23 1499.81 1.00 1640 39 74 2 FALSE 0.03
non-small cell lung cancer KRAS_G12A CDK12 81 45 White -0.69 -3.34 1.09 1460.87 1.00 2792 80 44 1 FALSE 0.25
colorectal cancer KRAS_G12A CDK12 41 76 Race:overall -0.05 -4.74 5.10 1462.18 1.00 1640 39 74 2 FALSE 0.01
non-small cell lung cancer KRAS_G12A CDK12 81 45 Race:overall -0.65 -5.28 3.78 1466.93 1.00 2792 80 44 1 FALSE 0.11
non-small cell lung cancer KRAS_G12A STK11 85 472 White 0.55 0.04 1.04 1359.24 1.00 2484 65 452 20 TRUE 1.51
non-small cell lung cancer KRAS_G12A STK11 92 536 Race:overall 0.65 -0.49 1.85 1600.94 1.00 3148 70 514 22 TRUE 0.59
colorectal cancer KRAS_G12A BRD4 40 69 White -0.92 -3.87 0.91 1244.27 1.00 1637 39 68 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A BRD4 81 40 White -4.91 -14.48 0.01 1328.37 1.00 2798 81 40 0 FALSE 0.69
colorectal cancer KRAS_G12A BRD4 40 69 Race:overall -0.76 -5.43 4.12 1174.27 1.00 1637 39 68 1 FALSE 0.13
non-small cell lung cancer KRAS_G12A BRD4 81 40 Race:overall -3.58 -11.44 3.16 1322.23 1.00 2798 81 40 0 FALSE 0.52
colorectal cancer KRAS_G12A ASXL1 40 85 White -1.22 -4.17 0.62 551.88 1.00 1625 39 84 1 TRUE 0.48
non-small cell lung cancer KRAS_G12A ASXL1 81 74 White -1.18 -3.78 0.71 1348.00 1.00 2777 80 73 1 TRUE 0.51
colorectal cancer KRAS_G12A ASXL1 40 85 Race:overall -0.95 -5.24 3.91 986.57 1.00 1625 39 84 1 TRUE 0.17
non-small cell lung cancer KRAS_G12A ASXL1 81 74 Race:overall -0.98 -5.52 4.32 1518.20 1.00 2777 80 73 1 TRUE 0.17
colorectal cancer KRAS_G12A EP300 40 107 White 0.43 -0.75 1.44 1316.49 1.00 1618 36 103 4 TRUE 0.36
non-small cell lung cancer KRAS_G12A EP300 81 91 White 0.67 -0.33 1.51 1447.23 1.00 2760 76 86 5 TRUE 0.80
colorectal cancer KRAS_G12A EP300 40 107 Race:overall 0.34 -4.16 4.90 1436.49 1.00 1618 36 103 4 TRUE 0.06
non-small cell lung cancer KRAS_G12A EP300 81 91 Race:overall 0.61 -4.10 4.77 1474.40 1.00 2760 76 86 5 TRUE 0.12
colorectal cancer KRAS_G12A ERBB4 45 109 White 0.26 -1.00 1.25 577.49 1.01 1794 41 105 4 TRUE 0.18
non-small cell lung cancer KRAS_G12A ERBB4 86 160 White 0.32 -0.54 1.13 1501.92 1.00 2793 80 154 6 TRUE 0.36
colorectal cancer KRAS_G12A ERBB4 47 122 Race:overall 0.06 -2.35 1.82 884.18 1.00 1911 43 118 4 TRUE 0.02
non-small cell lung cancer KRAS_G12A ERBB4 88 177 Race:overall 0.57 -1.26 2.65 1476.17 1.00 2976 81 170 7 TRUE 0.27
non-small cell lung cancer KRAS_G12A MDC1 81 73 White -1.39 -4.45 0.43 1541.89 1.00 2770 80 72 1 FALSE 0.58
non-small cell lung cancer KRAS_G12A MDC1 84 86 Race:overall -1.50 -4.94 1.01 1505.55 1.00 2933 83 85 1 FALSE 0.50
non-small cell lung cancer KRAS_G12A RECQL4 81 50 White -5.42 -15.88 -0.12 1297.99 1.00 2788 81 50 0 TRUE 0.66
non-small cell lung cancer KRAS_G12A RECQL4 81 50 Race:overall -4.00 -11.70 2.94 1116.34 1.00 2788 81 50 0 TRUE 0.56
colorectal cancer KRAS_G12A MED12 40 95 White -6.05 -15.82 -0.74 667.82 1.00 1621 40 95 0 TRUE 0.56
non-small cell lung cancer KRAS_G12A MED12 81 146 White 0.37 -0.56 1.15 1061.15 1.00 2708 75 140 6 TRUE 0.39
colorectal cancer KRAS_G12A MED12 40 95 Race:overall -4.41 -11.37 2.39 981.94 1.00 1621 40 95 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A MED12 81 146 Race:overall 0.33 -3.54 4.20 1445.80 1.00 2708 75 140 6 TRUE 0.07
non-small cell lung cancer KRAS_G12A ERCC5 81 57 White -1.00 -3.56 0.88 1288.06 1.00 2783 80 56 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A ERCC5 81 57 Race:overall -0.84 -5.44 4.00 1501.92 1.00 2783 80 56 1 TRUE 0.15
colorectal cancer KRAS_G12A BRCA1 40 56 White -0.83 -3.29 1.07 183.42 1.02 1652 39 55 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A BRCA1 82 79 White 0.50 -0.75 1.46 1368.68 1.00 2764 78 75 4 TRUE 0.43
colorectal cancer KRAS_G12A BRCA1 40 56 Race:overall -0.64 -4.95 4.60 1005.70 1.01 1652 39 55 1 TRUE 0.10
non-small cell lung cancer KRAS_G12A BRCA1 82 79 Race:overall 0.48 -3.92 4.97 1411.89 1.00 2764 78 75 4 TRUE 0.09
colorectal cancer KRAS_G12A RBM10 40 54 White -5.23 -14.32 -0.12 1428.02 1.00 1651 40 54 0 FALSE 0.71
non-small cell lung cancer KRAS_G12A RBM10 81 314 White 0.90 0.32 1.40 1566.30 1.00 2556 63 296 18 FALSE 3.04
colorectal cancer KRAS_G12A RBM10 40 54 Race:overall -3.85 -10.98 3.30 1116.88 1.00 1651 40 54 0 FALSE 0.55
non-small cell lung cancer KRAS_G12A RBM10 88 381 Race:overall 0.88 0.02 1.77 1468.41 1.00 3185 68 361 20 FALSE 1.38
colorectal cancer KRAS_G12A TSC1 40 60 White -5.01 -14.24 -0.13 1210.78 1.00 1652 40 60 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A TSC1 81 44 White 0.79 -0.59 1.95 636.47 1.00 2796 78 41 3 TRUE 0.67
colorectal cancer KRAS_G12A TSC1 40 60 Race:overall -3.71 -11.33 3.04 1379.70 1.00 1652 40 60 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A TSC1 81 44 Race:overall 0.72 -3.60 5.00 1475.98 1.00 2796 78 41 3 TRUE 0.14
colorectal cancer KRAS_G12A FLCN 40 45 White 0.97 -0.48 2.16 1163.37 1.00 1663 37 42 3 TRUE 0.84
colorectal cancer KRAS_G12A FLCN 40 45 Race:overall 0.87 -4.21 5.81 1392.78 1.00 1663 37 42 3 TRUE 0.15
colorectal cancer KRAS_G12A NF1 41 113 White -0.54 -2.23 0.84 1288.06 1.00 1616 39 111 2 TRUE 0.31
non-small cell lung cancer KRAS_G12A NF1 81 254 White -1.10 -2.39 -0.07 1173.93 1.00 2626 78 251 3 TRUE 1.22
colorectal cancer KRAS_G12A NF1 41 113 Race:overall -0.49 -4.90 4.38 1397.67 1.00 1616 39 111 2 TRUE 0.08
non-small cell lung cancer KRAS_G12A NF1 88 307 Race:overall -1.17 -2.73 0.07 1129.72 1.00 3267 85 304 3 TRUE 0.99
colorectal cancer KRAS_G12A FLT1 40 68 White -5.60 -16.52 -0.44 1149.35 1.00 1644 40 68 0 FALSE 0.69
non-small cell lung cancer KRAS_G12A FLT1 82 118 White 0.36 -0.72 1.25 1157.01 1.00 2733 77 113 5 FALSE 0.33
colorectal cancer KRAS_G12A FLT1 40 68 Race:overall -4.10 -11.86 3.54 975.33 1.00 1644 40 68 0 FALSE 0.56
non-small cell lung cancer KRAS_G12A FLT1 82 118 Race:overall 0.33 -3.92 4.40 1375.79 1.00 2733 77 113 5 FALSE 0.06
colorectal cancer KRAS_G12A RPTOR 40 52 White -0.62 -3.58 1.26 1062.51 1.01 1652 39 51 1 FALSE 0.21
non-small cell lung cancer KRAS_G12A RPTOR 81 58 White -0.88 -3.70 0.90 1110.94 1.00 2781 80 57 1 FALSE 0.34
colorectal cancer KRAS_G12A RPTOR 40 52 Race:overall -0.47 -5.42 4.31 1269.63 1.00 1652 39 51 1 FALSE 0.08
non-small cell lung cancer KRAS_G12A RPTOR 81 58 Race:overall -0.77 -5.38 3.78 1242.23 1.00 2781 80 57 1 FALSE 0.14
colorectal cancer KRAS_G12A RASA1 42 58 White 0.69 -0.72 1.87 1386.04 1.00 1656 39 55 3 FALSE 0.54
non-small cell lung cancer KRAS_G12A RASA1 81 84 White -5.71 -15.67 -0.67 1264.12 1.00 2753 81 84 0 FALSE 0.77
colorectal cancer KRAS_G12A RASA1 42 58 Race:overall 0.54 -4.62 4.86 1467.77 1.00 1656 39 55 3 FALSE 0.10
non-small cell lung cancer KRAS_G12A RASA1 81 84 Race:overall -4.07 -11.83 2.72 1398.60 1.00 2753 81 84 0 FALSE 0.59
colorectal cancer KRAS_G12A EPHA5 40 115 White -0.75 -2.61 0.52 891.46 1.00 1602 39 114 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A EPHA5 82 213 White -0.30 -1.30 0.51 1428.68 1.00 2646 77 208 5 FALSE 0.28
colorectal cancer KRAS_G12A EPHA5 45 138 Race:overall -0.67 -2.49 0.67 951.58 1.00 1862 43 136 2 FALSE 0.39
non-small cell lung cancer KRAS_G12A EPHA5 89 255 Race:overall -0.49 -2.14 0.73 1416.38 1.00 3299 84 250 5 FALSE 0.29
colorectal cancer KRAS_G12A AR 40 86 White -1.18 -3.95 0.64 1265.99 1.00 1619 39 85 1 TRUE 0.49
non-small cell lung cancer KRAS_G12A AR 81 80 White -0.75 -2.95 0.68 1579.51 1.00 2762 80 79 1 TRUE 0.37
colorectal cancer KRAS_G12A AR 40 86 Race:overall -0.95 -5.65 4.30 1243.16 1.00 1619 39 85 1 TRUE 0.16
non-small cell lung cancer KRAS_G12A AR 83 93 Race:overall -0.05 -2.80 3.06 1661.30 1.00 2944 81 91 2 TRUE 0.01
colorectal cancer KRAS_G12A GNAS 44 66 White 0.07 -1.80 1.39 1200.69 1.00 1828 42 64 2 TRUE 0.03
colorectal cancer KRAS_G12A GNAS 44 66 Race:overall 0.04 -4.52 4.23 1479.19 1.00 1828 42 64 2 TRUE 0.01
colorectal cancer KRAS_G12A ASXL2 40 60 White -5.07 -13.88 -0.24 1159.57 1.00 1658 40 60 0 FALSE 0.73
non-small cell lung cancer KRAS_G12A ASXL2 81 53 White -0.78 -3.56 1.21 403.26 1.01 2787 80 52 1 FALSE 0.28
colorectal cancer KRAS_G12A ASXL2 40 60 Race:overall -3.74 -11.19 3.30 958.52 1.00 1658 40 60 0 FALSE 0.55
non-small cell lung cancer KRAS_G12A ASXL2 81 53 Race:overall -0.67 -5.54 4.38 912.56 1.00 2787 80 52 1 FALSE 0.11
colorectal cancer KRAS_G12A SF3B1 40 51 White -0.63 -3.31 1.17 1413.49 1.00 1659 39 50 1 TRUE 0.23
non-small cell lung cancer KRAS_G12A SF3B1 82 71 White 0.86 -0.21 1.76 974.24 1.00 2772 77 66 5 TRUE 1.07
colorectal cancer KRAS_G12A SF3B1 40 51 Race:overall -0.47 -5.15 4.62 1437.25 1.00 1659 39 50 1 TRUE 0.07
non-small cell lung cancer KRAS_G12A SF3B1 82 71 Race:overall 0.67 -4.31 5.14 1369.28 1.00 2772 77 66 5 TRUE 0.12
colorectal cancer KRAS_G12A MLH1 44 49 White -4.72 -14.36 0.07 144.24 1.04 1847 44 49 0 TRUE 0.56
colorectal cancer KRAS_G12A MLH1 44 49 Race:overall -3.44 -11.43 3.29 306.18 1.03 1847 44 49 0 TRUE 0.47
colorectal cancer KRAS_G12A ROS1 40 71 White -4.81 -11.58 -0.52 1196.30 1.00 1635 40 71 0 TRUE 1.00
non-small cell lung cancer KRAS_G12A ROS1 81 93 White -0.01 -1.42 1.12 1442.16 1.00 2751 78 90 3 TRUE 0.01
colorectal cancer KRAS_G12A ROS1 43 87 Race:overall -4.59 -11.31 -0.23 1189.40 1.00 1771 43 87 0 TRUE 0.96
non-small cell lung cancer KRAS_G12A ROS1 81 93 Race:overall -0.06 -4.58 4.35 1495.00 1.00 2751 78 90 3 TRUE 0.01
colorectal cancer KRAS_G12A PIK3R2 40 36 White -5.00 -14.70 0.31 1131.99 1.00 1665 40 36 0 FALSE 0.57
colorectal cancer KRAS_G12A PIK3R2 40 36 Race:overall -3.66 -11.30 3.36 1237.19 1.00 1665 40 36 0 FALSE 0.51
colorectal cancer KRAS_G12A FLT3 44 36 White -5.07 -13.87 0.14 950.76 1.00 1855 44 36 0 TRUE 0.75
non-small cell lung cancer KRAS_G12A FLT3 84 62 White -0.12 -1.84 1.20 1412.15 1.00 2868 82 60 2 TRUE 0.06
colorectal cancer KRAS_G12A FLT3 44 36 Race:overall -3.90 -10.83 2.52 405.54 1.01 1855 44 36 0 TRUE 0.60
non-small cell lung cancer KRAS_G12A FLT3 84 62 Race:overall -0.06 -4.38 4.23 1311.75 1.00 2868 82 60 2 TRUE 0.01
colorectal cancer KRAS_G12A MSH2 40 63 White -5.11 -15.43 -0.16 1071.44 1.00 1654 40 63 0 TRUE 0.67
non-small cell lung cancer KRAS_G12A MSH2 81 45 White -5.25 -13.97 -0.02 805.15 1.01 2795 81 45 0 TRUE 0.59
colorectal cancer KRAS_G12A MSH2 40 63 Race:overall -3.68 -10.78 2.93 928.35 1.01 1654 40 63 0 TRUE 0.56
non-small cell lung cancer KRAS_G12A MSH2 81 45 Race:overall -3.76 -11.34 3.32 1146.24 1.00 2795 81 45 0 TRUE 0.52
non-small cell lung cancer KRAS_G12A DIS3 81 53 White 0.57 -0.84 1.72 1401.36 1.00 2787 78 50 3 FALSE 0.41
non-small cell lung cancer KRAS_G12A DIS3 81 53 Race:overall 0.51 -3.84 4.97 1288.94 1.00 2787 78 50 3 FALSE 0.09
colorectal cancer KRAS_G12A AXL 40 67 White -0.98 -3.61 0.86 573.38 1.01 1644 39 66 1 FALSE 0.39
colorectal cancer KRAS_G12A AXL 40 67 Race:overall -0.92 -5.65 4.52 739.95 1.01 1644 39 66 1 FALSE 0.16
colorectal cancer KRAS_G12A PIK3CG 40 89 White -1.21 -3.86 0.54 1230.53 1.00 1621 39 88 1 FALSE 0.51
non-small cell lung cancer KRAS_G12A PIK3CG 82 151 White 0.26 -0.74 1.09 590.07 1.00 2705 76 145 6 FALSE 0.26
colorectal cancer KRAS_G12A PIK3CG 40 89 Race:overall -1.00 -5.52 3.74 1306.13 1.00 1621 39 88 1 FALSE 0.19
non-small cell lung cancer KRAS_G12A PIK3CG 84 163 Race:overall 0.12 -1.89 1.71 900.24 1.00 2886 78 157 6 FALSE 0.05
colorectal cancer KRAS_G12A MAP2K4 40 53 White 0.24 -1.68 1.60 1163.76 1.00 1651 38 51 2 TRUE 0.12
colorectal cancer KRAS_G12A MAP2K4 40 53 Race:overall 0.20 -4.39 4.63 1548.80 1.00 1651 38 51 2 TRUE 0.03
colorectal cancer KRAS_G12A EGFR 44 59 White -5.26 -14.73 -0.08 1272.77 1.00 1835 44 59 0 TRUE 0.70
non-small cell lung cancer KRAS_G12A EGFR 84 694 White -3.73 -6.26 -1.99 1408.89 1.00 2360 83 693 1 TRUE 3.15
colorectal cancer KRAS_G12A EGFR 44 59 Race:overall -3.92 -11.02 2.81 1006.95 1.00 1835 44 59 0 TRUE 0.58
non-small cell lung cancer KRAS_G12A EGFR 91 1038 Race:overall -3.79 -6.43 -1.73 1500.23 1.00 2854 90 1037 1 TRUE 2.79
colorectal cancer KRAS_G12A ARID1B 40 121 White -5.55 -14.12 -0.83 870.69 1.00 1599 40 121 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A ARID1B 81 82 White 0.44 -0.74 1.43 1102.30 1.00 2761 77 78 4 TRUE 0.36
colorectal cancer KRAS_G12A ARID1B 40 121 Race:overall -4.07 -11.23 2.43 1227.16 1.00 1599 40 121 0 TRUE 0.65
non-small cell lung cancer KRAS_G12A ARID1B 83 94 Race:overall 0.21 -2.60 2.40 1420.45 1.00 3078 79 90 4 TRUE 0.06
non-small cell lung cancer KRAS_G12A INSR 81 48 White -0.87 -3.39 0.90 1072.50 1.00 2792 80 47 1 FALSE 0.39
non-small cell lung cancer KRAS_G12A INSR 81 48 Race:overall -0.67 -4.87 3.81 1396.91 1.00 2792 80 47 1 FALSE 0.12
non-small cell lung cancer KRAS_G12A NKX2-1 81 58 White 0.52 -0.89 1.58 1435.93 1.00 2789 78 55 3 TRUE 0.38
non-small cell lung cancer KRAS_G12A NKX2-1 81 58 Race:overall 0.48 -4.03 5.20 1577.17 1.00 2789 78 55 3 TRUE 0.08
colorectal cancer KRAS_G12A ARID5B 40 53 White -0.71 -3.57 1.18 1115.62 1.00 1662 39 52 1 FALSE 0.26
colorectal cancer KRAS_G12A ARID5B 40 53 Race:overall -0.60 -5.50 4.37 1509.37 1.00 1662 39 52 1 FALSE 0.10
non-small cell lung cancer KRAS_G12A WT1 81 60 White -1.01 -4.07 0.81 1381.12 1.00 2780 80 59 1 TRUE 0.39
non-small cell lung cancer KRAS_G12A WT1 81 60 Race:overall -0.88 -5.78 3.79 1313.62 1.00 2780 80 59 1 TRUE 0.15
non-small cell lung cancer KRAS_G12A MET 84 140 White -0.45 -1.84 0.69 1005.97 1.00 2800 81 137 3 TRUE 0.33
non-small cell lung cancer KRAS_G12A MET 86 153 Race:overall -0.59 -3.44 1.85 1446.35 1.00 3137 83 150 3 TRUE 0.19
non-small cell lung cancer KRAS_G12A PMS1 81 44 White 0.29 -1.53 1.56 1115.09 1.00 2795 79 42 2 TRUE 0.14
non-small cell lung cancer KRAS_G12A PMS1 81 44 Race:overall 0.21 -4.41 4.64 1355.58 1.00 2795 79 42 2 TRUE 0.04
non-small cell lung cancer KRAS_G12A PIK3C3 81 62 White 0.76 -0.42 1.74 1184.31 1.00 2780 77 58 4 FALSE 0.80
non-small cell lung cancer KRAS_G12A PIK3C3 81 62 Race:overall 0.62 -3.49 4.45 1374.69 1.00 2780 77 58 4 FALSE 0.13
colorectal cancer KRAS_G12A BRAF 44 207 White -2.39 -4.98 -0.55 95.24 1.03 1692 43 206 1 TRUE 1.36
non-small cell lung cancer KRAS_G12A BRAF 84 167 White -2.04 -4.89 -0.28 1467.56 1.00 2762 83 166 1 TRUE 1.06
colorectal cancer KRAS_G12A BRAF 53 249 Race:overall -2.40 -5.01 -0.53 97.76 1.03 2102 52 248 1 TRUE 1.34
non-small cell lung cancer KRAS_G12A BRAF 84 167 Race:overall -1.66 -6.07 3.44 1566.26 1.00 2762 83 166 1 TRUE 0.33
non-small cell lung cancer KRAS_G12A TGFBR1 81 37 White 0.98 -0.46 2.13 1194.13 1.00 2802 78 34 3 FALSE 0.86
non-small cell lung cancer KRAS_G12A TGFBR1 81 37 Race:overall 0.80 -4.37 5.06 1539.15 1.00 2802 78 34 3 FALSE 0.15
colorectal cancer KRAS_G12A TET2 40 67 White -0.88 -3.99 0.98 1341.80 1.00 1646 39 66 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A TET2 81 66 White -5.30 -14.13 -0.65 396.43 1.02 2775 81 66 0 TRUE 0.78
colorectal cancer KRAS_G12A TET2 40 67 Race:overall -0.71 -5.35 4.48 1401.91 1.00 1646 39 66 1 TRUE 0.12
non-small cell lung cancer KRAS_G12A TET2 81 66 Race:overall -4.05 -11.32 2.77 942.12 1.01 2775 81 66 0 TRUE 0.65
colorectal cancer KRAS_G12A PDGFRB 40 38 White -0.42 -3.35 1.47 1060.51 1.00 1664 39 37 1 TRUE 0.13
non-small cell lung cancer KRAS_G12A PDGFRB 81 82 White -0.38 -2.10 0.98 1460.72 1.00 2763 79 80 2 TRUE 0.20
colorectal cancer KRAS_G12A PDGFRB 40 38 Race:overall -0.34 -5.08 4.93 1376.31 1.00 1664 39 37 1 TRUE 0.05
non-small cell lung cancer KRAS_G12A PDGFRB 81 82 Race:overall -0.34 -4.52 4.04 1467.11 1.00 2763 79 80 2 TRUE 0.06
colorectal cancer KRAS_G12A CARD11 40 106 White -0.38 -2.15 0.91 1478.37 1.00 1607 38 104 2 FALSE 0.20
non-small cell lung cancer KRAS_G12A CARD11 81 100 White 0.30 -0.85 1.23 1483.80 1.00 2746 77 96 4 FALSE 0.24
colorectal cancer KRAS_G12A CARD11 40 106 Race:overall -0.36 -4.59 4.07 1587.75 1.00 1607 38 104 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A CARD11 81 100 Race:overall 0.26 -4.38 4.79 1415.63 1.00 2746 77 96 4 FALSE 0.05
colorectal cancer KRAS_G12A DNMT3A 40 40 White -5.09 -15.33 0.21 1412.59 1.00 1664 40 40 0 TRUE 0.52
non-small cell lung cancer KRAS_G12A DNMT3A 81 66 White -6.33 -14.39 -0.79 54.91 1.05 2771 81 66 0 TRUE 0.62
colorectal cancer KRAS_G12A DNMT3A 40 40 Race:overall -3.69 -11.72 3.21 1168.14 1.00 1664 40 40 0 TRUE 0.50
non-small cell lung cancer KRAS_G12A DNMT3A 81 66 Race:overall -5.23 -11.66 2.40 10.16 1.18 2771 81 66 0 TRUE 0.79
colorectal cancer KRAS_G12A MSH6 40 83 White -1.11 -3.92 0.66 1396.92 1.00 1634 39 82 1 TRUE 0.47
colorectal cancer KRAS_G12A MSH6 40 83 Race:overall -0.98 -5.83 3.69 1547.45 1.00 1634 39 82 1 TRUE 0.17
non-small cell lung cancer KRAS_G12A MAX 81 46 White 1.41 0.42 2.34 1244.69 1.00 2796 76 41 5 FALSE 2.44
non-small cell lung cancer KRAS_G12A MAX 81 46 Race:overall 1.12 -3.82 4.95 1409.55 1.00 2796 76 41 5 FALSE 0.22
non-small cell lung cancer KRAS_G12A INPP4B 81 111 White 0.43 -0.57 1.27 295.31 1.00 2739 76 106 5 FALSE 0.42
non-small cell lung cancer KRAS_G12A INPP4B 81 111 Race:overall 0.31 -3.86 4.30 1246.45 1.00 2739 76 106 5 FALSE 0.06
non-small cell lung cancer KRAS_G12A NFE2L2 81 101 White -1.52 -4.33 0.30 1322.04 1.00 2745 80 100 1 FALSE 0.68
non-small cell lung cancer KRAS_G12A NFE2L2 81 101 Race:overall -1.21 -5.86 3.81 1384.36 1.00 2745 80 100 1 FALSE 0.22
colorectal cancer KRAS_G12A SOX9 43 209 White 0.71 -0.05 1.41 655.31 1.00 1517 34 200 9 FALSE 1.26
colorectal cancer KRAS_G12A SOX9 50 245 Race:overall 0.72 -0.17 1.55 730.30 1.00 1777 39 234 11 FALSE 1.06
colorectal cancer KRAS_G12A ARAF 40 50 White -5.47 -15.63 0.01 312.76 1.01 1656 40 50 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A ARAF 81 52 White 0.03 -1.98 1.41 1014.18 1.00 2791 79 50 2 FALSE 0.01
colorectal cancer KRAS_G12A ARAF 40 50 Race:overall -4.05 -12.39 3.10 163.69 1.01 1656 40 50 0 FALSE 0.51
non-small cell lung cancer KRAS_G12A ARAF 81 52 Race:overall 0.04 -4.52 4.56 1476.73 1.00 2791 79 50 2 FALSE 0.01
non-small cell lung cancer KRAS_G12A JAK2 85 62 White -0.13 -1.82 1.22 1139.70 1.00 2866 83 60 2 TRUE 0.06
non-small cell lung cancer KRAS_G12A JAK2 85 62 Race:overall -0.11 -4.72 4.20 1447.00 1.00 2866 83 60 2 TRUE 0.02
colorectal cancer KRAS_G12A SMAD2 40 74 White -0.05 -1.79 1.32 1130.61 1.00 1639 38 72 2 TRUE 0.02
colorectal cancer KRAS_G12A SMAD2 40 74 Race:overall 0.04 -4.46 4.83 1661.80 1.00 1639 38 72 2 TRUE 0.01
non-small cell lung cancer KRAS_G12A TP63 81 63 White -1.00 -3.82 0.78 961.39 1.00 2776 80 62 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A TP63 81 63 Race:overall -0.91 -5.90 3.68 1487.98 1.00 2776 80 62 1 FALSE 0.16
non-small cell lung cancer KRAS_G12A MYOD1 81 46 White -5.29 -15.24 -0.06 1070.87 1.00 2794 81 46 0 FALSE 0.73
non-small cell lung cancer KRAS_G12A MYOD1 81 46 Race:overall -3.83 -11.04 2.92 1301.88 1.00 2794 81 46 0 FALSE 0.56
colorectal cancer KRAS_G12A FGFR1 44 37 White -4.93 -14.43 0.26 1041.62 1.00 1855 44 37 0 TRUE 0.65
colorectal cancer KRAS_G12A FGFR1 44 37 Race:overall -3.55 -11.48 3.40 953.05 1.00 1855 44 37 0 TRUE 0.47
colorectal cancer KRAS_G12A MITF 40 42 White -4.80 -14.22 0.05 984.03 1.00 1658 40 42 0 FALSE 0.71
colorectal cancer KRAS_G12A MITF 40 42 Race:overall -3.60 -11.23 2.80 1179.40 1.00 1658 40 42 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A BTK 81 49 White -5.17 -14.82 -0.11 1419.18 1.00 2788 81 49 0 TRUE 0.69
non-small cell lung cancer KRAS_G12A BTK 81 49 Race:overall -3.73 -11.04 3.30 1487.61 1.00 2788 81 49 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A GLI1 76 90 White -1.47 -4.31 0.37 1325.68 1.00 2461 75 89 1 FALSE 0.66
non-small cell lung cancer KRAS_G12A GLI1 76 90 Race:overall -1.16 -6.24 4.18 1488.42 1.00 2461 75 89 1 FALSE 0.20
non-small cell lung cancer KRAS_G12A ZFHX3 76 136 White 0.13 -0.90 1.03 1090.86 1.01 2418 71 131 5 FALSE 0.10
non-small cell lung cancer KRAS_G12A ZFHX3 78 147 Race:overall -0.08 -2.67 1.52 1322.94 1.00 2584 73 142 5 FALSE 0.03
non-small cell lung cancer KRAS_G12A MGA 76 163 White -0.04 -1.08 0.84 1110.35 1.00 2409 71 158 5 FALSE 0.03
non-small cell lung cancer KRAS_G12A MGA 78 178 Race:overall -0.22 -3.01 1.92 1395.07 1.00 2688 73 173 5 FALSE 0.07
non-small cell lung cancer KRAS_G12A ANKRD11 76 64 White -0.15 -2.11 1.21 1374.72 1.00 2485 74 62 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A ANKRD11 76 64 Race:overall -0.10 -4.28 4.41 1283.51 1.00 2485 74 62 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A PGR 76 63 White -1.26 -4.13 0.57 1254.84 1.00 2484 75 62 1 FALSE 0.53
non-small cell lung cancer KRAS_G12A PGR 78 76 Race:overall -1.38 -4.81 1.27 1274.36 1.00 2648 77 75 1 FALSE 0.41
non-small cell lung cancer KRAS_G12A PLCG2 76 52 White -0.83 -3.70 1.09 1191.55 1.00 2499 75 51 1 FALSE 0.31
non-small cell lung cancer KRAS_G12A PLCG2 76 52 Race:overall -0.78 -5.45 3.52 1364.51 1.00 2499 75 51 1 FALSE 0.14
non-small cell lung cancer KRAS_G12A POLD1 76 49 White -5.35 -15.26 -0.09 1305.00 1.00 2496 76 49 0 TRUE 0.62
non-small cell lung cancer KRAS_G12A POLD1 76 49 Race:overall -3.73 -11.27 3.14 1497.53 1.00 2496 76 49 0 TRUE 0.51
non-small cell lung cancer KRAS_G12A INHBA 76 75 White -1.28 -3.96 0.55 1501.11 1.00 2476 75 74 1 FALSE 0.55
non-small cell lung cancer KRAS_G12A INHBA 76 75 Race:overall -1.11 -5.95 3.75 1398.16 1.00 2476 75 74 1 FALSE 0.20
colorectal cancer KRAS_G12A AMER1 40 135 White -1.74 -4.34 0.15 428.64 1.01 1579 39 134 1 FALSE 0.88
non-small cell lung cancer KRAS_G12A AMER1 81 127 White 0.25 -0.80 1.13 1205.48 1.00 2731 76 122 5 FALSE 0.22
colorectal cancer KRAS_G12A AMER1 44 147 Race:overall -1.75 -4.62 0.37 482.44 1.00 1711 43 146 1 FALSE 0.79
non-small cell lung cancer KRAS_G12A AMER1 83 143 Race:overall 0.00 -2.71 1.97 1345.34 1.00 2911 78 138 5 FALSE 0.00
non-small cell lung cancer KRAS_G12A EPHA7 76 110 White -0.73 -2.50 0.59 1213.76 1.00 2442 74 108 2 FALSE 0.45
non-small cell lung cancer KRAS_G12A EPHA7 76 110 Race:overall -0.52 -4.90 4.06 1379.08 1.00 2442 74 108 2 FALSE 0.09
colorectal cancer KRAS_G12C SPEN 58 121 White -5.32 -12.58 -1.11 1020.60 1.00 1594 58 121 0 FALSE 1.17
non-small cell lung cancer KRAS_G12C SPEN 406 101 White -1.02 -1.96 -0.20 1161.64 1.00 2446 400 95 6 FALSE 1.69
colorectal cancer KRAS_G12C SPEN 60 132 Race:overall -5.17 -12.21 -0.72 949.78 1.00 1730 60 132 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C SPEN 406 101 Race:overall -0.80 -4.45 3.81 1396.81 1.00 2446 400 95 6 FALSE 0.16
colorectal cancer KRAS_G12C KMT2C 58 157 White -5.50 -12.07 -1.62 936.02 1.00 1569 58 157 0 FALSE 1.24
non-small cell lung cancer KRAS_G12C KMT2C 12 14 Asian -0.02 -1.61 1.46 1423.66 1.00 304 11 13 1 FALSE 0.01
non-small cell lung cancer KRAS_G12C KMT2C 19 11 Black -0.61 -2.82 0.77 1259.61 1.00 164 19 11 0 FALSE 0.29
non-small cell lung cancer KRAS_G12C KMT2C 406 185 White 0.04 -0.37 0.43 1535.00 1.00 2369 379 158 27 FALSE 0.07
colorectal cancer KRAS_G12C KMT2C 65 194 Race:overall -5.47 -12.08 -1.56 935.63 1.00 1964 65 194 0 FALSE 1.23
non-small cell lung cancer KRAS_G12C KMT2C 437 210 Race:overall -0.21 -1.73 0.92 1463.12 1.00 2837 409 182 28 FALSE 0.13
colorectal cancer KRAS_G12C TP53 69 1350 White -0.28 -0.74 0.18 1054.55 1.00 657 27 1308 42 TRUE 0.62
non-small cell lung cancer KRAS_G12C TP53 13 173 Asian -0.74 -1.40 0.01 1464.29 1.00 179 7 167 6 TRUE 1.44
non-small cell lung cancer KRAS_G12C TP53 20 128 Black -0.72 -1.36 -0.04 1513.74 1.00 69 11 119 9 TRUE 1.58
non-small cell lung cancer KRAS_G12C TP53 17 98 Unknown -1.09 -1.99 -0.39 1441.41 1.00 76 14 95 3 TRUE 2.27
non-small cell lung cancer KRAS_G12C TP53 428 1617 White -0.67 -0.88 -0.47 1474.83 1.00 1240 268 1457 160 TRUE 9.90
colorectal cancer KRAS_G12C TP53 79 1713 Race:overall -0.48 -1.29 0.21 1466.67 1.00 821 32 1666 47 TRUE 0.74
non-small cell lung cancer KRAS_G12C TP53 482 2050 Race:overall -0.80 -1.35 -0.27 1316.46 1.01 1589 302 1870 180 TRUE 2.51
colorectal cancer KRAS_G12C ATRX 58 96 White -1.47 -3.99 0.06 48.16 1.06 1602 57 95 1 TRUE 0.78
non-small cell lung cancer KRAS_G12C ATRX 19 11 Black 0.30 -0.99 1.13 1295.66 1.00 167 18 10 1 TRUE 0.25
non-small cell lung cancer KRAS_G12C ATRX 409 186 White 0.48 0.12 0.84 338.69 1.02 2386 370 147 39 TRUE 2.29
colorectal cancer KRAS_G12C ATRX 58 96 Race:overall -1.31 -5.73 3.14 1157.96 1.01 1602 57 95 1 TRUE 0.28
non-small cell lung cancer KRAS_G12C ATRX 428 197 Race:overall 0.38 -0.69 1.17 1436.95 1.00 2553 388 157 40 TRUE 0.37
colorectal cancer KRAS_G12C ATR 58 88 White -5.05 -11.64 -1.09 1070.90 1.00 1617 58 88 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C ATR 405 103 White -0.24 -0.88 0.35 1416.36 1.00 2426 393 91 12 FALSE 0.34
colorectal cancer KRAS_G12C ATR 60 99 Race:overall -4.82 -11.33 -0.58 1129.51 1.00 1757 60 99 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C ATR 405 103 Race:overall -0.28 -4.33 3.84 1313.02 1.00 2426 393 91 12 FALSE 0.05
colorectal cancer KRAS_G12C PDGFRA 66 44 White 0.06 -1.84 1.37 966.67 1.00 1824 64 42 2 TRUE 0.03
non-small cell lung cancer KRAS_G12C PDGFRA 12 13 Asian 1.05 -0.19 2.33 1567.23 1.00 327 10 11 2 TRUE 0.97
non-small cell lung cancer KRAS_G12C PDGFRA 18 12 Unknown 1.02 -0.05 2.16 1592.48 1.00 153 15 9 3 TRUE 1.11
non-small cell lung cancer KRAS_G12C PDGFRA 419 112 White 0.47 -0.02 0.91 1615.31 1.00 2506 397 90 22 TRUE 1.32
colorectal cancer KRAS_G12C PDGFRA 66 44 Race:overall 0.07 -4.62 4.72 1577.78 1.00 1824 64 42 2 TRUE 0.01
non-small cell lung cancer KRAS_G12C PDGFRA 449 137 Race:overall 0.83 -0.24 1.96 1436.16 1.00 2986 422 110 27 TRUE 0.82
colorectal cancer KRAS_G12C FBXW7 68 254 White -0.05 -0.78 0.59 1187.81 1.00 1652 58 244 10 TRUE 0.05
non-small cell lung cancer KRAS_G12C FBXW7 421 64 White -0.16 -0.97 0.54 1414.29 1.00 2538 413 56 8 TRUE 0.17
colorectal cancer KRAS_G12C FBXW7 77 334 Race:overall -0.26 -1.41 0.62 1277.94 1.00 2033 67 324 10 TRUE 0.21
non-small cell lung cancer KRAS_G12C FBXW7 421 64 Race:overall -0.06 -4.19 4.11 1354.52 1.00 2538 413 56 8 TRUE 0.01
colorectal cancer KRAS_G12C MAP3K1 58 70 White -0.34 -2.11 0.94 1024.91 1.00 1622 56 68 2 FALSE 0.18
non-small cell lung cancer KRAS_G12C MAP3K1 405 56 White 0.34 -0.50 1.03 52.48 1.06 2469 394 45 11 FALSE 0.41
colorectal cancer KRAS_G12C MAP3K1 58 70 Race:overall -0.32 -5.16 4.18 1266.61 1.00 1622 56 68 2 FALSE 0.06
non-small cell lung cancer KRAS_G12C MAP3K1 405 56 Race:overall 0.14 -4.94 4.18 1460.50 1.00 2469 394 45 11 FALSE 0.02
colorectal cancer KRAS_G12C NSD1 58 71 White -1.41 -4.41 0.47 1312.00 1.00 1624 57 70 1 FALSE 0.58
non-small cell lung cancer KRAS_G12C NSD1 405 67 White 0.04 -0.67 0.67 1492.68 1.00 2456 395 57 10 FALSE 0.04
colorectal cancer KRAS_G12C NSD1 58 71 Race:overall -1.16 -6.14 3.98 1348.58 1.00 1624 57 70 1 FALSE 0.21
non-small cell lung cancer KRAS_G12C NSD1 405 67 Race:overall 0.05 -4.12 4.92 1544.16 1.00 2456 395 57 10 FALSE 0.01
colorectal cancer KRAS_G12C FLT4 58 115 White -1.84 -4.58 -0.08 728.96 1.00 1583 57 114 1 TRUE 0.92
non-small cell lung cancer KRAS_G12C FLT4 405 84 White 0.17 -0.40 0.73 610.71 1.01 2445 391 70 14 TRUE 0.26
colorectal cancer KRAS_G12C FLT4 58 115 Race:overall -1.49 -5.69 3.70 1331.88 1.00 1583 57 114 1 TRUE 0.28
non-small cell lung cancer KRAS_G12C FLT4 405 84 Race:overall 0.04 -4.10 4.21 1427.88 1.00 2445 391 70 14 TRUE 0.01
colorectal cancer KRAS_G12C PTPRD 58 85 White -1.52 -4.09 0.29 1261.44 1.00 1614 57 84 1 FALSE 0.73
non-small cell lung cancer KRAS_G12C PTPRD 12 18 Asian 0.00 -1.22 1.21 1393.73 1.00 301 11 17 1 FALSE 0.00
non-small cell lung cancer KRAS_G12C PTPRD 19 27 Black -0.13 -1.28 0.82 1467.88 1.00 152 17 25 2 FALSE 0.10
non-small cell lung cancer KRAS_G12C PTPRD 15 21 Unknown -0.19 -1.46 0.83 1304.34 1.00 147 14 20 1 FALSE 0.13
non-small cell lung cancer KRAS_G12C PTPRD 415 320 White 0.23 -0.08 0.53 1308.55 1.00 2285 361 266 54 FALSE 0.83
colorectal cancer KRAS_G12C PTPRD 58 85 Race:overall -1.26 -5.79 3.72 1454.97 1.00 1614 57 84 1 FALSE 0.24
non-small cell lung cancer KRAS_G12C PTPRD 461 386 Race:overall -0.03 -0.90 0.79 1402.47 1.00 2885 403 328 58 FALSE 0.03
colorectal cancer KRAS_G12C RET 66 58 White 0.67 -0.60 1.60 710.44 1.01 1813 62 54 4 TRUE 0.66
non-small cell lung cancer KRAS_G12C RET 418 81 White 0.57 0.00 1.07 1242.83 1.00 2530 400 63 18 TRUE 1.39
colorectal cancer KRAS_G12C RET 66 58 Race:overall 0.61 -3.69 4.72 1392.30 1.00 1813 62 54 4 TRUE 0.12
non-small cell lung cancer KRAS_G12C RET 418 81 Race:overall 0.48 -4.10 5.01 1323.61 1.00 2530 400 63 18 TRUE 0.09
colorectal cancer KRAS_G12C KDM5A 58 74 White -5.73 -14.40 -0.79 1176.14 1.00 1623 58 74 0 FALSE 0.84
non-small cell lung cancer KRAS_G12C KDM5A 406 62 White 0.35 -0.36 0.98 845.58 1.00 2465 394 50 12 FALSE 0.53
colorectal cancer KRAS_G12C KDM5A 58 74 Race:overall -4.35 -11.51 2.03 899.87 1.00 1623 58 74 0 FALSE 0.67
non-small cell lung cancer KRAS_G12C KDM5A 406 62 Race:overall 0.29 -4.40 4.74 1171.80 1.00 2465 394 50 12 FALSE 0.05
colorectal cancer KRAS_G12C PIK3C2G 58 65 White -1.29 -4.34 0.52 1291.13 1.00 1625 57 64 1 FALSE 0.53
non-small cell lung cancer KRAS_G12C PIK3C2G 406 113 White -0.25 -0.85 0.33 1124.03 1.00 2419 393 100 13 FALSE 0.39
colorectal cancer KRAS_G12C PIK3C2G 58 65 Race:overall -1.01 -5.61 3.82 1412.50 1.00 1625 57 64 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C PIK3C2G 406 113 Race:overall -0.20 -4.11 3.66 1499.74 1.00 2419 393 100 13 FALSE 0.04
non-small cell lung cancer KRAS_G12C TSHR 406 58 White 0.46 -0.28 1.08 1434.25 1.00 2468 394 46 12 TRUE 0.74
non-small cell lung cancer KRAS_G12C TSHR 406 58 Race:overall 0.39 -4.19 4.66 1552.50 1.00 2468 394 46 12 TRUE 0.07
colorectal cancer KRAS_G12C CREBBP 58 148 White -0.83 -2.44 0.25 536.61 1.00 1571 55 145 3 TRUE 0.64
non-small cell lung cancer KRAS_G12C CREBBP 405 122 White -0.25 -0.85 0.26 1178.67 1.00 2414 391 108 14 TRUE 0.41
colorectal cancer KRAS_G12C CREBBP 65 183 Race:overall -0.86 -2.52 0.32 578.35 1.00 1965 62 180 3 TRUE 0.64
non-small cell lung cancer KRAS_G12C CREBBP 405 122 Race:overall -0.19 -4.35 4.19 1285.95 1.00 2414 391 108 14 TRUE 0.03
non-small cell lung cancer KRAS_G12C BRIP1 405 53 White 0.06 -0.75 0.76 1212.25 1.00 2468 397 45 8 TRUE 0.06
non-small cell lung cancer KRAS_G12C BRIP1 405 53 Race:overall -0.02 -4.89 3.94 1424.99 1.00 2468 397 45 8 TRUE 0.00
colorectal cancer KRAS_G12C AXIN2 58 87 White -5.88 -14.47 -0.85 1108.27 1.00 1608 58 87 0 TRUE 0.86
non-small cell lung cancer KRAS_G12C AXIN2 405 52 White 0.05 -0.77 0.81 1124.72 1.00 2468 397 44 8 TRUE 0.04
colorectal cancer KRAS_G12C AXIN2 58 87 Race:overall -4.29 -11.62 2.81 1053.22 1.00 1608 58 87 0 TRUE 0.62
non-small cell lung cancer KRAS_G12C AXIN2 405 52 Race:overall 0.08 -4.23 4.36 1235.79 1.00 2468 397 44 8 TRUE 0.01
colorectal cancer KRAS_G12C DOT1L 58 67 White -1.18 -3.87 0.50 204.51 1.02 1628 57 66 1 FALSE 0.50
non-small cell lung cancer KRAS_G12C DOT1L 406 88 White 0.03 -0.56 0.60 1475.12 1.00 2439 393 75 13 FALSE 0.03
colorectal cancer KRAS_G12C DOT1L 58 67 Race:overall -1.02 -6.13 3.77 1481.56 1.00 1628 57 66 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C DOT1L 406 88 Race:overall 0.02 -4.01 4.14 1530.45 1.00 2439 393 75 13 FALSE 0.00
colorectal cancer KRAS_G12C PTPRS 58 200 White -1.15 -2.54 -0.06 440.97 1.00 1525 55 197 3 FALSE 1.11
non-small cell lung cancer KRAS_G12C PTPRS 409 69 White 0.69 0.12 1.24 948.73 1.00 2462 392 52 17 FALSE 1.82
colorectal cancer KRAS_G12C PTPRS 65 251 Race:overall -1.18 -2.77 0.01 572.80 1.00 1903 62 248 3 FALSE 1.04
non-small cell lung cancer KRAS_G12C PTPRS 409 69 Race:overall 0.65 -3.91 4.68 1440.08 1.00 2462 392 52 17 FALSE 0.13
colorectal cancer KRAS_G12C SMARCA4 58 126 White -2.06 -4.74 -0.25 1381.19 1.00 1582 57 125 1 FALSE 1.13
non-small cell lung cancer KRAS_G12C SMARCA4 12 11 Asian -0.19 -1.67 1.01 1657.38 1.00 307 12 11 0 FALSE 0.11
non-small cell lung cancer KRAS_G12C SMARCA4 20 24 Black 0.16 -0.91 1.15 1473.22 1.00 156 17 21 3 FALSE 0.12
non-small cell lung cancer KRAS_G12C SMARCA4 15 11 Unknown -0.03 -1.38 1.23 1596.18 1.00 150 14 10 1 FALSE 0.02
non-small cell lung cancer KRAS_G12C SMARCA4 408 264 White 0.13 -0.22 0.47 1483.13 1.00 2303 367 223 41 FALSE 0.33
colorectal cancer KRAS_G12C SMARCA4 63 159 Race:overall -2.08 -4.98 -0.07 1410.72 1.00 1831 62 158 1 FALSE 1.04
non-small cell lung cancer KRAS_G12C SMARCA4 455 310 Race:overall 0.01 -0.94 0.94 1564.04 1.00 2916 410 265 45 FALSE 0.01
colorectal cancer KRAS_G12C PTPRT 60 150 White 0.05 -0.86 0.87 1009.65 1.00 1552 54 144 6 FALSE 0.04
non-small cell lung cancer KRAS_G12C PTPRT 12 12 Asian 0.66 -0.56 1.94 1497.64 1.00 308 10 10 2 FALSE 0.50
non-small cell lung cancer KRAS_G12C PTPRT 19 21 Black 0.17 -0.95 1.13 1508.93 1.00 159 17 19 2 FALSE 0.12
non-small cell lung cancer KRAS_G12C PTPRT 15 16 Unknown 0.57 -0.56 1.70 1497.23 1.00 149 12 13 3 FALSE 0.49
non-small cell lung cancer KRAS_G12C PTPRT 407 299 White -0.07 -0.42 0.27 1408.98 1.00 2304 369 261 38 FALSE 0.16
colorectal cancer KRAS_G12C PTPRT 63 162 Race:overall -0.05 -1.61 1.24 1395.49 1.00 1669 57 156 6 FALSE 0.02
non-small cell lung cancer KRAS_G12C PTPRT 453 348 Race:overall 0.33 -0.56 1.27 1590.88 1.00 2920 408 303 45 FALSE 0.33
colorectal cancer KRAS_G12C HGF 58 39 White 0.21 -1.62 1.58 1377.58 1.00 1649 56 37 2 FALSE 0.10
non-small cell lung cancer KRAS_G12C HGF 19 17 Black 0.12 -0.95 1.08 1272.25 1.00 161 17 15 2 FALSE 0.09
non-small cell lung cancer KRAS_G12C HGF 407 156 White 0.10 -0.36 0.54 825.22 1.00 2390 383 132 24 FALSE 0.18
colorectal cancer KRAS_G12C HGF 58 39 Race:overall 0.09 -4.73 4.28 1443.26 1.00 1649 56 37 2 FALSE 0.01
non-small cell lung cancer KRAS_G12C HGF 426 173 Race:overall 0.11 -0.91 1.10 1348.60 1.00 2551 400 147 26 FALSE 0.08
colorectal cancer KRAS_G12C BLM 58 50 White -5.70 -14.67 -0.46 207.91 1.01 1641 58 50 0 TRUE 0.75
colorectal cancer KRAS_G12C BLM 58 50 Race:overall -4.21 -11.27 3.00 83.40 1.02 1641 58 50 0 TRUE 0.57
colorectal cancer KRAS_G12C PIK3CA 66 403 White -0.46 -1.19 0.17 383.82 1.02 1513 58 395 8 TRUE 0.74
non-small cell lung cancer KRAS_G12C PIK3CA 12 31 Asian -0.16 -1.55 1.07 1377.15 1.00 307 11 30 1 TRUE 0.10
non-small cell lung cancer KRAS_G12C PIK3CA 20 13 Black 0.10 -1.05 1.32 1261.71 1.00 169 18 11 2 TRUE 0.06
non-small cell lung cancer KRAS_G12C PIK3CA 419 189 White -0.12 -0.57 0.29 1438.86 1.00 2433 395 165 24 TRUE 0.24
colorectal cancer KRAS_G12C PIK3CA 75 498 Race:overall -0.39 -1.21 0.39 519.42 1.01 1884 64 487 11 TRUE 0.48
non-small cell lung cancer KRAS_G12C PIK3CA 451 233 Race:overall -0.06 -1.10 0.98 1390.38 1.00 2909 424 206 27 TRUE 0.04
non-small cell lung cancer KRAS_G12C GATA3 405 57 White 0.83 0.21 1.40 213.83 1.01 2474 390 42 15 FALSE 2.13
non-small cell lung cancer KRAS_G12C GATA3 405 57 Race:overall 0.62 -4.20 4.53 1390.32 1.00 2474 390 42 15 FALSE 0.12
colorectal cancer KRAS_G12C ESR1 58 61 White -0.26 -2.04 1.13 1268.57 1.00 1626 56 59 2 TRUE 0.13
non-small cell lung cancer KRAS_G12C ESR1 405 45 White -0.62 -1.78 0.42 1502.80 1.00 2474 401 41 4 TRUE 0.56
colorectal cancer KRAS_G12C ESR1 58 61 Race:overall -0.25 -4.79 4.31 1456.41 1.00 1626 56 59 2 TRUE 0.04
non-small cell lung cancer KRAS_G12C ESR1 405 45 Race:overall -0.51 -4.46 3.76 1625.30 1.00 2474 401 41 4 TRUE 0.10
colorectal cancer KRAS_G12C ALK 66 95 White -0.74 -2.62 0.69 1177.37 1.00 1787 64 93 2 TRUE 0.43
non-small cell lung cancer KRAS_G12C ALK 12 13 Asian 0.47 -1.33 2.09 1446.35 1.00 326 11 12 1 TRUE 0.23
non-small cell lung cancer KRAS_G12C ALK 418 141 White 0.45 0.03 0.86 1460.81 1.00 2486 390 113 28 TRUE 1.47
colorectal cancer KRAS_G12C ALK 66 95 Race:overall -0.70 -5.15 4.12 1479.02 1.00 1787 64 93 2 TRUE 0.13
non-small cell lung cancer KRAS_G12C ALK 430 154 Race:overall 0.44 -1.46 2.33 1321.03 1.00 2812 401 125 29 TRUE 0.19
colorectal cancer KRAS_G12C RNF43 58 217 White -2.54 -5.26 -0.80 782.54 1.01 1522 57 216 1 TRUE 1.55
colorectal cancer KRAS_G12C RNF43 62 253 Race:overall -2.54 -5.41 -0.59 973.22 1.01 1791 61 252 1 TRUE 1.39
non-small cell lung cancer KRAS_G12C U2AF1 405 65 White 0.53 -0.08 1.12 1255.61 1.00 2463 391 51 14 FALSE 1.07
non-small cell lung cancer KRAS_G12C U2AF1 405 65 Race:overall 0.50 -4.04 5.07 1504.45 1.00 2463 391 51 14 FALSE 0.09
colorectal cancer KRAS_G12C LATS1 58 40 White -5.58 -15.64 -0.15 1262.95 1.00 1647 58 40 0 FALSE 0.56
non-small cell lung cancer KRAS_G12C LATS1 405 59 White -1.76 -3.51 -0.36 1110.52 1.00 2456 403 57 2 FALSE 1.55
colorectal cancer KRAS_G12C LATS1 58 40 Race:overall -3.92 -11.76 3.21 1444.99 1.00 1647 58 40 0 FALSE 0.55
non-small cell lung cancer KRAS_G12C LATS1 405 59 Race:overall -1.53 -5.88 2.97 1485.26 1.00 2456 403 57 2 FALSE 0.33
colorectal cancer KRAS_G12C LATS2 58 58 White -1.16 -3.92 0.62 1281.86 1.00 1628 57 57 1 FALSE 0.49
non-small cell lung cancer KRAS_G12C LATS2 405 45 White -0.12 -1.11 0.75 1349.59 1.00 2473 399 39 6 FALSE 0.09
colorectal cancer KRAS_G12C LATS2 58 58 Race:overall -0.96 -5.23 3.47 1481.84 1.00 1628 57 57 1 FALSE 0.18
non-small cell lung cancer KRAS_G12C LATS2 405 45 Race:overall -0.08 -4.58 4.25 1545.96 1.00 2473 399 39 6 FALSE 0.01
colorectal cancer KRAS_G12C PTEN 66 141 White -0.87 -2.31 0.22 976.65 1.00 1762 64 139 2 TRUE 0.74
non-small cell lung cancer KRAS_G12C PTEN 12 13 Asian -1.43 -5.88 0.86 1341.89 1.00 325 12 13 0 TRUE 0.38
non-small cell lung cancer KRAS_G12C PTEN 418 111 White -0.57 -1.28 0.07 1510.09 1.00 2495 408 101 10 TRUE 1.04
colorectal cancer KRAS_G12C PTEN 75 181 Race:overall -0.80 -2.33 0.41 857.04 1.00 2182 72 178 3 TRUE 0.59
non-small cell lung cancer KRAS_G12C PTEN 430 124 Race:overall -0.90 -3.58 1.44 1381.26 1.00 2820 420 114 10 TRUE 0.33
colorectal cancer KRAS_G12C BCOR 58 94 White -1.66 -4.41 0.10 1335.57 1.00 1606 57 93 1 FALSE 0.82
non-small cell lung cancer KRAS_G12C BCOR 409 117 White 0.10 -0.41 0.60 452.68 1.00 2419 391 99 18 FALSE 0.15
colorectal cancer KRAS_G12C BCOR 58 94 Race:overall -1.24 -5.72 4.35 1520.56 1.00 1606 57 93 1 FALSE 0.22
non-small cell lung cancer KRAS_G12C BCOR 409 117 Race:overall 0.04 -4.34 4.44 1564.53 1.00 2419 391 99 18 FALSE 0.01
colorectal cancer KRAS_G12C CTNNB1 66 124 White 0.17 -0.76 1.00 1236.10 1.00 1754 60 118 6 TRUE 0.16
non-small cell lung cancer KRAS_G12C CTNNB1 12 17 Asian -1.21 -3.87 0.49 1528.50 1.00 320 12 17 0 TRUE 0.55
non-small cell lung cancer KRAS_G12C CTNNB1 20 11 Black -1.30 -3.81 0.38 1451.64 1.00 168 20 11 0 TRUE 0.61
non-small cell lung cancer KRAS_G12C CTNNB1 419 88 White -0.53 -1.32 0.14 1517.31 1.00 2513 410 79 9 TRUE 0.79
colorectal cancer KRAS_G12C CTNNB1 72 152 Race:overall 0.06 -1.19 1.06 1307.27 1.00 2052 66 146 6 TRUE 0.04
non-small cell lung cancer KRAS_G12C CTNNB1 451 116 Race:overall -0.99 -2.89 0.53 1409.41 1.00 3001 442 107 9 TRUE 0.61
colorectal cancer KRAS_G12C ARID1A 58 249 White -0.95 -2.16 -0.06 61.88 1.03 1515 54 245 4 TRUE 1.05
non-small cell lung cancer KRAS_G12C ARID1A 12 20 Asian 0.48 -0.77 1.68 1533.69 1.00 303 10 18 2 TRUE 0.35
non-small cell lung cancer KRAS_G12C ARID1A 19 20 Black 0.16 -1.05 1.19 1475.96 1.00 157 17 18 2 TRUE 0.11
non-small cell lung cancer KRAS_G12C ARID1A 411 231 White 0.18 -0.20 0.52 1766.06 1.00 2333 374 194 37 TRUE 0.47
colorectal cancer KRAS_G12C ARID1A 65 310 Race:overall -0.97 -2.29 -0.08 60.73 1.03 1890 61 306 4 TRUE 0.98
non-small cell lung cancer KRAS_G12C ARID1A 442 271 Race:overall 0.25 -0.82 1.23 1511.04 1.00 2793 401 230 41 TRUE 0.20
colorectal cancer KRAS_G12C PIK3R1 58 95 White -0.73 -2.39 0.61 1217.23 1.00 1606 56 93 2 TRUE 0.46
non-small cell lung cancer KRAS_G12C PIK3R1 405 41 White 0.00 -1.02 0.82 1493.72 1.00 2477 399 35 6 TRUE 0.00
colorectal cancer KRAS_G12C PIK3R1 58 95 Race:overall -0.66 -4.78 3.72 1338.60 1.00 1606 56 93 2 TRUE 0.13
non-small cell lung cancer KRAS_G12C PIK3R1 405 41 Race:overall 0.02 -4.09 4.49 1428.20 1.00 2477 399 35 6 TRUE 0.00
colorectal cancer KRAS_G12C IKZF1 58 69 White -0.40 -2.21 0.91 1369.81 1.00 1620 56 67 2 TRUE 0.21
non-small cell lung cancer KRAS_G12C IKZF1 405 67 White 0.17 -0.50 0.79 843.97 1.00 2457 394 56 11 TRUE 0.22
colorectal cancer KRAS_G12C IKZF1 58 69 Race:overall -0.37 -4.71 3.95 1492.43 1.00 1620 56 67 2 TRUE 0.07
non-small cell lung cancer KRAS_G12C IKZF1 405 67 Race:overall 0.18 -4.30 4.79 1501.59 1.00 2457 394 56 11 TRUE 0.03
colorectal cancer KRAS_G12C TERT 58 75 White 0.38 -0.78 1.42 1517.22 1.00 1620 54 71 4 TRUE 0.31
non-small cell lung cancer KRAS_G12C TERT 12 11 Asian -0.67 -5.57 1.53 1304.93 1.00 308 12 11 0 TRUE 0.15
non-small cell lung cancer KRAS_G12C TERT 407 135 White 0.63 0.20 1.02 1586.69 1.00 2412 376 104 31 TRUE 2.47
colorectal cancer KRAS_G12C TERT 58 75 Race:overall 0.35 -4.20 5.07 1387.66 1.00 1620 54 71 4 TRUE 0.06
non-small cell lung cancer KRAS_G12C TERT 419 146 Race:overall 0.00 -3.10 2.09 1423.66 1.00 2720 388 115 31 TRUE 0.00
colorectal cancer KRAS_G12C FAT1 58 180 White -5.68 -11.97 -1.67 1193.19 1.00 1553 58 180 0 FALSE 1.45
non-small cell lung cancer KRAS_G12C FAT1 12 13 Asian -0.40 -2.17 0.97 1530.91 1.00 304 12 13 0 FALSE 0.22
non-small cell lung cancer KRAS_G12C FAT1 19 12 Black -0.55 -2.29 0.65 1538.17 1.00 165 19 12 0 FALSE 0.32
non-small cell lung cancer KRAS_G12C FAT1 15 15 Unknown -0.24 -1.72 0.91 1413.63 1.00 146 14 14 1 FALSE 0.14
non-small cell lung cancer KRAS_G12C FAT1 409 261 White 0.30 -0.06 0.63 1497.10 1.00 2323 362 214 47 FALSE 1.07
colorectal cancer KRAS_G12C FAT1 65 225 Race:overall -5.66 -12.05 -1.61 1185.22 1.00 1952 65 225 0 FALSE 1.43
non-small cell lung cancer KRAS_G12C FAT1 455 301 Race:overall -0.22 -1.46 0.68 1517.23 1.00 2938 407 253 48 FALSE 0.17
colorectal cancer KRAS_G12C FGFR4 58 39 White -5.46 -15.22 -0.24 1249.34 1.00 1647 58 39 0 TRUE 0.71
colorectal cancer KRAS_G12C FGFR4 58 39 Race:overall -3.95 -11.97 3.44 1015.96 1.00 1647 58 39 0 TRUE 0.53
colorectal cancer KRAS_G12C CIC 58 111 White -0.76 -2.57 0.40 66.35 1.03 1595 56 109 2 TRUE 0.45
non-small cell lung cancer KRAS_G12C CIC 409 81 White 0.04 -0.64 0.62 1511.12 1.00 2451 397 69 12 TRUE 0.04
colorectal cancer KRAS_G12C CIC 58 111 Race:overall -0.72 -5.12 3.63 699.58 1.00 1595 56 109 2 TRUE 0.14
non-small cell lung cancer KRAS_G12C CIC 409 81 Race:overall 0.09 -4.46 4.20 1532.22 1.00 2451 397 69 12 TRUE 0.02
colorectal cancer KRAS_G12C KDM6A 58 49 White -5.51 -15.43 -0.62 987.09 1.00 1638 58 49 0 FALSE 0.75
non-small cell lung cancer KRAS_G12C KDM6A 405 45 White -0.61 -1.80 0.36 1039.19 1.00 2473 401 41 4 FALSE 0.60
colorectal cancer KRAS_G12C KDM6A 58 49 Race:overall -3.91 -11.29 3.35 1031.69 1.00 1638 58 49 0 FALSE 0.56
non-small cell lung cancer KRAS_G12C KDM6A 405 45 Race:overall -0.51 -4.71 3.93 1435.55 1.00 2473 401 41 4 FALSE 0.09
colorectal cancer KRAS_G12C NCOR1 58 108 White -5.28 -12.10 -1.10 668.40 1.00 1599 58 108 0 FALSE 1.14
non-small cell lung cancer KRAS_G12C NCOR1 407 82 White 0.28 -0.34 0.78 15.56 1.09 2450 393 68 14 FALSE 0.54
colorectal cancer KRAS_G12C NCOR1 60 120 Race:overall -5.08 -11.78 -0.74 685.56 1.00 1737 60 120 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C NCOR1 407 82 Race:overall 0.29 -3.36 3.69 1099.06 1.00 2450 393 68 14 FALSE 0.07
colorectal cancer KRAS_G12C POLE 58 115 White -5.41 -12.24 -1.17 1252.17 1.00 1588 58 115 0 TRUE 1.16
non-small cell lung cancer KRAS_G12C POLE 406 112 White 0.51 0.07 0.96 722.12 1.01 2430 382 88 24 TRUE 1.59
colorectal cancer KRAS_G12C POLE 60 128 Race:overall -5.22 -12.08 -0.60 1266.48 1.00 1728 60 128 0 TRUE 1.12
non-small cell lung cancer KRAS_G12C POLE 406 112 Race:overall 0.42 -3.94 4.39 1388.19 1.00 2430 382 88 24 TRUE 0.08
non-small cell lung cancer KRAS_G12C CUL3 406 64 White 0.31 -0.37 0.92 1119.36 1.00 2466 394 52 12 FALSE 0.46
non-small cell lung cancer KRAS_G12C CUL3 406 64 Race:overall 0.27 -4.08 4.57 1535.37 1.00 2466 394 52 12 FALSE 0.05
colorectal cancer KRAS_G12C ABL1 66 59 White -5.67 -15.81 -0.55 1206.93 1.00 1815 66 59 0 TRUE 0.65
colorectal cancer KRAS_G12C ABL1 66 59 Race:overall -4.01 -11.76 2.68 1472.55 1.00 1815 66 59 0 TRUE 0.58
colorectal cancer KRAS_G12C FOXP1 58 56 White -1.11 -3.67 0.68 1327.10 1.00 1633 57 55 1 FALSE 0.47
colorectal cancer KRAS_G12C FOXP1 58 56 Race:overall -0.96 -5.42 3.88 1541.65 1.00 1633 57 55 1 FALSE 0.18
colorectal cancer KRAS_G12C NOTCH2 58 64 White -5.53 -15.60 -0.58 1140.23 1.00 1628 58 64 0 TRUE 0.78
non-small cell lung cancer KRAS_G12C NOTCH2 405 98 White -0.41 -1.14 0.24 822.48 1.00 2434 395 88 10 TRUE 0.57
colorectal cancer KRAS_G12C NOTCH2 58 64 Race:overall -4.02 -11.55 3.10 1170.22 1.00 1628 58 64 0 TRUE 0.59
non-small cell lung cancer KRAS_G12C NOTCH2 405 98 Race:overall -0.35 -4.47 4.15 1349.25 1.00 2434 395 88 10 TRUE 0.07
non-small cell lung cancer KRAS_G12C DDR2 405 82 White 0.03 -0.66 0.63 1546.82 1.00 2442 393 70 12 TRUE 0.03
non-small cell lung cancer KRAS_G12C DDR2 405 82 Race:overall 0.11 -4.23 4.35 1565.31 1.00 2442 393 70 12 TRUE 0.02
colorectal cancer KRAS_G12C TGFBR2 58 93 White -5.95 -16.41 -0.99 901.13 1.00 1596 58 93 0 TRUE 0.75
non-small cell lung cancer KRAS_G12C TGFBR2 406 48 White 0.58 -0.14 1.25 1213.62 1.00 2478 395 37 11 TRUE 0.99
colorectal cancer KRAS_G12C TGFBR2 58 93 Race:overall -4.34 -12.00 2.66 1204.83 1.00 1596 58 93 0 TRUE 0.65
non-small cell lung cancer KRAS_G12C TGFBR2 406 48 Race:overall 0.50 -3.86 4.54 1420.83 1.00 2478 395 37 11 TRUE 0.09
colorectal cancer KRAS_G12C SMO 66 57 White -5.50 -15.46 -0.43 1211.92 1.00 1814 66 57 0 TRUE 0.70
non-small cell lung cancer KRAS_G12C SMO 418 64 White 0.22 -0.45 0.86 1478.66 1.00 2540 407 53 11 TRUE 0.29
colorectal cancer KRAS_G12C SMO 66 57 Race:overall -4.00 -11.60 2.54 1110.18 1.00 1814 66 57 0 TRUE 0.60
non-small cell lung cancer KRAS_G12C SMO 418 64 Race:overall 0.15 -4.63 4.48 1481.32 1.00 2540 407 53 11 TRUE 0.03
colorectal cancer KRAS_G12C RPS6KA4 58 46 White -1.00 -3.73 0.89 1433.50 1.00 1640 57 45 1 FALSE 0.39
colorectal cancer KRAS_G12C RPS6KA4 58 46 Race:overall -0.83 -5.60 3.92 1229.69 1.00 1640 57 45 1 FALSE 0.14
colorectal cancer KRAS_G12C KMT2A 58 122 White -1.01 -2.75 0.34 1333.13 1.00 1585 56 120 2 FALSE 0.68
non-small cell lung cancer KRAS_G12C KMT2A 405 99 White 0.10 -0.51 0.64 489.58 1.00 2434 390 84 15 FALSE 0.13
colorectal cancer KRAS_G12C KMT2A 58 122 Race:overall -0.84 -5.25 3.77 1366.40 1.00 1585 56 120 2 FALSE 0.16
non-small cell lung cancer KRAS_G12C KMT2A 405 99 Race:overall 0.08 -4.15 4.39 1548.70 1.00 2434 390 84 15 FALSE 0.01
colorectal cancer KRAS_G12C JAK3 66 51 White -0.05 -1.94 1.23 427.51 1.01 1821 64 49 2 TRUE 0.02
non-small cell lung cancer KRAS_G12C JAK3 419 73 White 0.36 -0.23 0.92 1521.49 1.00 2533 405 59 14 TRUE 0.65
colorectal cancer KRAS_G12C JAK3 66 51 Race:overall -0.15 -4.98 4.57 1285.47 1.00 1821 64 49 2 TRUE 0.03
non-small cell lung cancer KRAS_G12C JAK3 419 73 Race:overall 0.27 -4.42 4.85 1013.17 1.00 2533 405 59 14 TRUE 0.05
non-small cell lung cancer KRAS_G12C PAK7 15 14 Unknown -0.28 -1.79 1.09 1444.14 1.00 149 14 13 1 FALSE 0.15
non-small cell lung cancer KRAS_G12C PAK7 405 107 White -0.20 -0.78 0.38 1203.78 1.00 2425 392 94 13 FALSE 0.29
non-small cell lung cancer KRAS_G12C PAK7 420 121 Race:overall -0.25 -1.87 1.25 1491.10 1.00 2574 406 107 14 FALSE 0.13
non-small cell lung cancer KRAS_G12C STAG2 405 85 White 0.28 -0.32 0.81 1165.06 1.00 2447 390 70 15 TRUE 0.47
non-small cell lung cancer KRAS_G12C STAG2 405 85 Race:overall 0.15 -4.47 4.34 1596.13 1.00 2447 390 70 15 TRUE 0.03
colorectal cancer KRAS_G12C BRCA2 58 149 White -1.23 -2.87 -0.15 174.63 1.03 1581 56 147 2 TRUE 1.07
non-small cell lung cancer KRAS_G12C BRCA2 12 12 Asian -0.90 -4.95 1.16 1449.17 1.00 307 12 12 0 TRUE 0.24
non-small cell lung cancer KRAS_G12C BRCA2 405 110 White 0.07 -0.45 0.59 1467.40 1.00 2429 388 93 17 TRUE 0.10
colorectal cancer KRAS_G12C BRCA2 62 180 Race:overall -1.28 -3.13 -0.03 191.55 1.03 1859 60 178 2 TRUE 0.94
non-small cell lung cancer KRAS_G12C BRCA2 417 122 Race:overall -0.38 -3.21 1.71 1412.91 1.00 2736 400 105 17 TRUE 0.13
colorectal cancer KRAS_G12C NOTCH3 58 154 White -4.77 -11.50 -1.46 24.70 1.09 1561 58 154 0 TRUE 1.13
non-small cell lung cancer KRAS_G12C NOTCH3 405 106 White -0.09 -0.70 0.46 1499.80 1.00 2428 391 92 14 TRUE 0.12
colorectal cancer KRAS_G12C NOTCH3 65 197 Race:overall -4.76 -11.44 -1.45 25.80 1.09 1947 65 197 0 TRUE 1.13
non-small cell lung cancer KRAS_G12C NOTCH3 405 106 Race:overall 0.00 -3.93 4.52 1462.15 1.00 2428 391 92 14 TRUE 0.00
colorectal cancer KRAS_G12C NOTCH4 58 99 White -0.30 -1.84 0.78 1420.32 1.00 1597 55 96 3 TRUE 0.19
non-small cell lung cancer KRAS_G12C NOTCH4 405 117 White -0.38 -1.02 0.22 1373.24 1.00 2413 393 105 12 TRUE 0.65
colorectal cancer KRAS_G12C NOTCH4 58 99 Race:overall -0.28 -4.67 4.41 1505.01 1.00 1597 55 96 3 TRUE 0.05
non-small cell lung cancer KRAS_G12C NOTCH4 405 117 Race:overall -0.30 -5.15 3.81 1345.59 1.00 2413 393 105 12 TRUE 0.05
colorectal cancer KRAS_G12C FGFR3 66 45 White -5.45 -15.52 -0.11 1389.17 1.00 1824 66 45 0 TRUE 0.71
colorectal cancer KRAS_G12C FGFR3 66 45 Race:overall -3.81 -11.81 3.36 1169.13 1.00 1824 66 45 0 TRUE 0.53
non-small cell lung cancer KRAS_G12C MAP3K13 405 42 White -0.51 -1.73 0.46 1010.76 1.00 2475 401 38 4 FALSE 0.44
non-small cell lung cancer KRAS_G12C MAP3K13 405 42 Race:overall -0.41 -4.46 3.89 1699.77 1.00 2475 401 38 4 FALSE 0.08
colorectal cancer KRAS_G12C IGF1R 58 69 White -5.80 -16.11 -0.58 843.80 1.00 1624 58 69 0 TRUE 0.58
non-small cell lung cancer KRAS_G12C IGF1R 405 39 White 0.87 0.11 1.54 1348.47 1.00 2484 394 28 11 TRUE 1.74
colorectal cancer KRAS_G12C IGF1R 58 69 Race:overall -4.17 -11.89 3.31 876.05 1.00 1624 58 69 0 TRUE 0.58
non-small cell lung cancer KRAS_G12C IGF1R 405 39 Race:overall 0.80 -3.42 5.68 1263.40 1.00 2484 394 28 11 TRUE 0.15
non-small cell lung cancer KRAS_G12C KEAP1 12 24 Asian 0.99 -0.01 2.17 1381.55 1.00 299 8 20 4 FALSE 1.15
non-small cell lung cancer KRAS_G12C KEAP1 19 28 Black 0.41 -0.54 1.24 1545.11 1.00 152 16 25 3 FALSE 0.43
non-small cell lung cancer KRAS_G12C KEAP1 15 19 Unknown 0.65 -0.28 1.63 1427.98 1.00 143 12 16 3 FALSE 0.75
non-small cell lung cancer KRAS_G12C KEAP1 410 461 White 0.45 0.18 0.71 1593.88 1.00 2151 324 375 86 FALSE 3.09
non-small cell lung cancer KRAS_G12C KEAP1 456 532 Race:overall 0.61 -0.18 1.39 1411.88 1.00 2745 360 436 96 FALSE 0.91
colorectal cancer KRAS_G12C KDM5C 58 51 White -1.17 -3.93 0.64 1364.65 1.00 1639 57 50 1 FALSE 0.48
non-small cell lung cancer KRAS_G12C KDM5C 405 87 White -0.16 -0.90 0.44 1286.49 1.00 2440 394 76 11 FALSE 0.19
colorectal cancer KRAS_G12C KDM5C 60 63 Race:overall -1.21 -4.48 1.45 1313.16 1.00 1778 59 62 1 FALSE 0.37
non-small cell lung cancer KRAS_G12C KDM5C 405 87 Race:overall -0.19 -4.64 4.30 1520.88 1.00 2440 394 76 11 FALSE 0.03
non-small cell lung cancer KRAS_G12C CDKN2A 12 15 Asian -0.63 -2.26 0.62 1562.28 1.00 323 12 15 0 TRUE 0.40
non-small cell lung cancer KRAS_G12C CDKN2A 20 18 Black -0.53 -1.97 0.56 1454.24 1.00 162 19 17 1 TRUE 0.39
non-small cell lung cancer KRAS_G12C CDKN2A 17 20 Unknown -0.54 -1.97 0.59 1589.09 1.00 143 16 19 1 TRUE 0.41
non-small cell lung cancer KRAS_G12C CDKN2A 422 218 White -0.16 -0.55 0.24 1588.21 1.00 2413 394 190 28 TRUE 0.35
non-small cell lung cancer KRAS_G12C CDKN2A 471 271 Race:overall -0.46 -1.63 0.45 1461.23 1.00 3041 441 241 30 TRUE 0.45
colorectal cancer KRAS_G12C EPHB1 58 65 White -5.37 -14.70 -0.38 772.92 1.00 1620 58 65 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C EPHB1 19 11 Black -0.66 -2.93 0.39 680.83 1.01 164 19 11 0 FALSE 0.34
non-small cell lung cancer KRAS_G12C EPHB1 406 135 White -0.33 -0.68 0.22 2.40 1.61 2407 389 118 17 FALSE 0.53
colorectal cancer KRAS_G12C EPHB1 58 65 Race:overall -4.00 -11.60 2.88 1112.11 1.00 1620 58 65 0 FALSE 0.58
non-small cell lung cancer KRAS_G12C EPHB1 425 146 Race:overall -0.50 -2.05 0.46 71.36 1.04 2571 408 129 17 FALSE 0.38
colorectal cancer KRAS_G12C IRS2 58 71 White -5.88 -16.28 -0.78 1128.23 1.00 1619 58 71 0 FALSE 0.55
non-small cell lung cancer KRAS_G12C IRS2 405 68 White -0.25 -1.06 0.45 1134.17 1.00 2454 397 60 8 FALSE 0.28
colorectal cancer KRAS_G12C IRS2 58 71 Race:overall -4.05 -11.64 3.00 1131.56 1.00 1619 58 71 0 FALSE 0.58
non-small cell lung cancer KRAS_G12C IRS2 405 68 Race:overall -0.21 -4.51 3.87 1483.78 1.00 2454 397 60 8 FALSE 0.04
colorectal cancer KRAS_G12C FANCA 58 51 White -5.61 -14.75 -0.32 473.08 1.00 1635 58 51 0 TRUE 0.65
non-small cell lung cancer KRAS_G12C FANCA 405 59 White -0.10 -0.93 0.61 1268.69 1.00 2463 397 51 8 TRUE 0.10
colorectal cancer KRAS_G12C FANCA 58 51 Race:overall -4.15 -11.85 3.23 295.69 1.00 1635 58 51 0 TRUE 0.59
non-small cell lung cancer KRAS_G12C FANCA 405 59 Race:overall -0.04 -4.55 4.46 1457.85 1.00 2463 397 51 8 TRUE 0.01
non-small cell lung cancer KRAS_G12C IL7R 406 69 White -0.02 -0.75 0.64 1311.90 1.00 2459 396 59 10 FALSE 0.02
non-small cell lung cancer KRAS_G12C IL7R 406 69 Race:overall 0.02 -4.32 4.67 1242.45 1.00 2459 396 59 10 FALSE 0.00
colorectal cancer KRAS_G12C PIK3CB 58 48 White -1.00 -3.87 0.89 1386.94 1.00 1645 57 47 1 FALSE 0.38
colorectal cancer KRAS_G12C PIK3CB 58 48 Race:overall -0.89 -5.94 4.07 1455.49 1.00 1645 57 47 1 FALSE 0.15
colorectal cancer KRAS_G12C ERBB3 58 94 White -0.29 -1.71 0.89 1046.45 1.00 1604 55 91 3 TRUE 0.18
colorectal cancer KRAS_G12C ERBB3 60 105 Race:overall -0.46 -3.01 1.47 1242.08 1.00 1742 57 102 3 TRUE 0.17
colorectal cancer KRAS_G12C SMAD4 66 274 White 0.20 -0.40 0.80 564.38 1.01 1627 54 262 12 TRUE 0.30
non-small cell lung cancer KRAS_G12C SMAD4 12 11 Asian 0.24 -1.82 2.04 1543.54 1.00 329 11 10 1 TRUE 0.09
non-small cell lung cancer KRAS_G12C SMAD4 418 89 White -0.26 -0.97 0.34 1478.29 1.00 2513 408 79 10 TRUE 0.37
colorectal cancer KRAS_G12C SMAD4 75 348 Race:overall 0.14 -0.68 0.88 1294.42 1.00 2011 62 335 13 TRUE 0.14
non-small cell lung cancer KRAS_G12C SMAD4 430 100 Race:overall -0.02 -2.10 1.98 1447.81 1.00 2842 419 89 11 TRUE 0.00
colorectal cancer KRAS_G12C ATM 67 176 White -0.73 -1.88 0.15 1011.53 1.01 1726 64 173 3 TRUE 0.82
non-small cell lung cancer KRAS_G12C ATM 12 13 Asian 1.09 0.08 2.17 1403.59 1.00 328 10 11 2 TRUE 1.44
non-small cell lung cancer KRAS_G12C ATM 21 15 Black 0.94 -0.03 1.82 1381.27 1.00 168 18 12 3 TRUE 1.37
non-small cell lung cancer KRAS_G12C ATM 17 11 Unknown 0.91 -0.10 1.87 1410.11 1.00 154 15 9 2 TRUE 1.15
non-small cell lung cancer KRAS_G12C ATM 430 245 White 1.03 0.74 1.32 1473.36 1.00 2432 359 174 71 TRUE 11.25
colorectal cancer KRAS_G12C ATM 76 227 Race:overall -0.70 -1.86 0.30 961.85 1.00 2146 72 223 4 TRUE 0.67
non-small cell lung cancer KRAS_G12C ATM 480 284 Race:overall 0.97 0.21 1.70 1499.66 1.00 3082 402 206 78 TRUE 2.02
colorectal cancer KRAS_G12C RB1 66 57 White -1.16 -3.94 0.66 1031.67 1.00 1820 65 56 1 TRUE 0.48
non-small cell lung cancer KRAS_G12C RB1 12 27 Asian -1.00 -2.54 0.13 1548.89 1.00 310 12 27 0 TRUE 0.88
non-small cell lung cancer KRAS_G12C RB1 20 18 Black -0.81 -2.05 0.32 1465.42 1.00 162 19 17 1 TRUE 0.75
non-small cell lung cancer KRAS_G12C RB1 17 11 Unknown -0.73 -1.90 0.47 1575.65 1.00 152 16 10 1 TRUE 0.63
non-small cell lung cancer KRAS_G12C RB1 418 164 White -0.80 -1.42 -0.26 1467.32 1.00 2444 406 152 12 TRUE 2.15
colorectal cancer KRAS_G12C RB1 66 57 Race:overall -0.96 -5.58 3.61 1288.19 1.00 1820 65 56 1 TRUE 0.18
non-small cell lung cancer KRAS_G12C RB1 467 220 Race:overall -0.83 -1.82 0.09 1444.78 1.00 3068 453 206 14 TRUE 1.08
colorectal cancer KRAS_G12C KMT2D 58 298 White -2.02 -3.78 -0.72 573.75 1.00 1504 56 296 2 FALSE 1.87
non-small cell lung cancer KRAS_G12C KMT2D 12 14 Asian -0.30 -1.99 1.02 1454.51 1.00 306 12 14 0 FALSE 0.16
non-small cell lung cancer KRAS_G12C KMT2D 19 22 Black -0.33 -1.72 0.76 1400.37 1.00 157 18 21 1 FALSE 0.23
non-small cell lung cancer KRAS_G12C KMT2D 15 20 Unknown 0.48 -0.61 1.61 1503.96 1.00 144 11 16 4 FALSE 0.41
non-small cell lung cancer KRAS_G12C KMT2D 407 266 White -0.08 -0.43 0.28 1623.27 1.00 2318 373 232 34 FALSE 0.19
colorectal cancer KRAS_G12C KMT2D 65 381 Race:overall -2.05 -3.88 -0.64 580.73 1.00 1874 63 379 2 FALSE 1.72
non-small cell lung cancer KRAS_G12C KMT2D 453 322 Race:overall -0.05 -1.09 0.89 1453.40 1.00 2925 414 283 39 FALSE 0.04
colorectal cancer KRAS_G12C TSC2 58 91 White -5.89 -16.16 -0.79 1042.99 1.00 1609 58 91 0 TRUE 0.73
non-small cell lung cancer KRAS_G12C TSC2 405 63 White -1.00 -2.07 -0.03 1088.75 1.00 2456 401 59 4 TRUE 1.24
colorectal cancer KRAS_G12C TSC2 58 91 Race:overall -4.21 -11.82 2.79 1060.56 1.00 1609 58 91 0 TRUE 0.63
non-small cell lung cancer KRAS_G12C TSC2 405 63 Race:overall -0.85 -4.91 3.97 1383.74 1.00 2456 401 59 4 TRUE 0.17
colorectal cancer KRAS_G12C APC 91 1977 White 0.28 -0.20 0.79 1526.47 1.00 642 17 1903 74 TRUE 0.57
non-small cell lung cancer KRAS_G12C APC 12 12 Asian -0.96 -3.92 0.79 1536.00 1.00 326 12 12 0 TRUE 0.38
non-small cell lung cancer KRAS_G12C APC 20 12 Black -1.15 -4.15 0.48 1448.53 1.00 167 20 12 0 TRUE 0.47
non-small cell lung cancer KRAS_G12C APC 421 125 White -0.19 -0.77 0.34 1685.03 1.00 2486 405 109 16 TRUE 0.30
colorectal cancer KRAS_G12C APC 102 2530 Race:overall -0.23 -1.14 0.56 1385.47 1.00 803 22 2450 80 TRUE 0.22
non-small cell lung cancer KRAS_G12C APC 453 149 Race:overall -0.76 -2.80 0.61 1515.45 1.00 2979 437 133 16 TRUE 0.43
colorectal cancer KRAS_G12C ERBB2 66 84 White 0.53 -0.52 1.49 1204.27 1.00 1794 61 79 5 TRUE 0.53
non-small cell lung cancer KRAS_G12C ERBB2 12 13 Asian -3.37 -7.56 -0.12 1382.36 1.00 324 12 13 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C ERBB2 418 101 White -3.29 -5.98 -1.53 1612.34 1.00 2495 417 100 1 TRUE 2.55
colorectal cancer KRAS_G12C ERBB2 66 84 Race:overall 0.56 -3.75 4.87 1420.14 1.00 1794 61 79 5 TRUE 0.11
non-small cell lung cancer KRAS_G12C ERBB2 430 114 Race:overall -3.13 -6.37 -0.08 1496.83 1.00 2819 429 113 1 TRUE 1.32
colorectal cancer KRAS_G12C JAK1 58 58 White -5.89 -15.76 -0.65 343.03 1.00 1633 58 58 0 TRUE 0.31
non-small cell lung cancer KRAS_G12C JAK1 405 41 White -0.24 -1.35 0.63 1397.51 1.00 2477 400 36 5 TRUE 0.20
colorectal cancer KRAS_G12C JAK1 58 58 Race:overall -4.04 -10.97 2.88 1105.71 1.00 1633 58 58 0 TRUE 0.62
non-small cell lung cancer KRAS_G12C JAK1 405 41 Race:overall -0.17 -4.55 4.00 1427.23 1.00 2477 400 36 5 TRUE 0.03
colorectal cancer KRAS_G12C ARID2 58 89 White -5.91 -16.12 -0.82 821.73 1.00 1604 58 89 0 FALSE 0.84
non-small cell lung cancer KRAS_G12C ARID2 12 17 Asian 0.20 -1.63 1.79 1385.10 1.00 304 11 16 1 FALSE 0.09
non-small cell lung cancer KRAS_G12C ARID2 406 145 White 0.22 -0.22 0.64 1499.13 1.00 2400 382 121 24 FALSE 0.49
colorectal cancer KRAS_G12C ARID2 58 89 Race:overall -4.43 -11.84 2.25 1180.99 1.00 1604 58 89 0 FALSE 0.70
non-small cell lung cancer KRAS_G12C ARID2 418 162 Race:overall 0.21 -1.62 2.13 1412.39 1.00 2704 393 137 25 FALSE 0.09
colorectal cancer KRAS_G12C SOX17 58 80 White -0.01 -1.34 1.04 1195.31 1.00 1613 55 77 3 FALSE 0.01
non-small cell lung cancer KRAS_G12C SOX17 405 51 White 0.46 -0.20 1.16 87.00 1.05 2473 394 40 11 FALSE 0.70
colorectal cancer KRAS_G12C SOX17 58 80 Race:overall -0.02 -4.49 4.34 1392.90 1.00 1613 55 77 3 FALSE 0.00
non-small cell lung cancer KRAS_G12C SOX17 405 51 Race:overall 0.36 -4.05 4.36 1584.39 1.00 2473 394 40 11 FALSE 0.07
colorectal cancer KRAS_G12C MTOR 58 111 White -0.39 -1.80 0.65 382.82 1.01 1592 55 108 3 TRUE 0.26
non-small cell lung cancer KRAS_G12C MTOR 407 92 White 0.54 -0.04 1.02 986.85 1.00 2440 387 72 20 TRUE 1.34
colorectal cancer KRAS_G12C MTOR 60 123 Race:overall -0.46 -2.84 1.30 792.94 1.00 1728 57 120 3 TRUE 0.18
non-small cell lung cancer KRAS_G12C MTOR 407 92 Race:overall 0.41 -4.16 4.67 1714.86 1.00 2440 387 72 20 TRUE 0.08
non-small cell lung cancer KRAS_G12C RFWD2 405 50 White 0.43 -0.31 1.13 822.06 1.00 2472 395 40 10 FALSE 0.62
non-small cell lung cancer KRAS_G12C RFWD2 405 50 Race:overall 0.35 -4.21 4.67 1508.56 1.00 2472 395 40 10 FALSE 0.06
colorectal cancer KRAS_G12C IRS1 58 81 White -1.51 -4.22 0.33 1282.06 1.00 1613 57 80 1 FALSE 0.69
non-small cell lung cancer KRAS_G12C IRS1 405 58 White -0.06 -0.94 0.63 627.98 1.01 2464 397 50 8 FALSE 0.05
colorectal cancer KRAS_G12C IRS1 58 81 Race:overall -1.26 -6.42 4.06 1212.34 1.00 1613 57 80 1 FALSE 0.22
non-small cell lung cancer KRAS_G12C IRS1 405 58 Race:overall -0.07 -4.14 4.02 1399.86 1.00 2464 397 50 8 FALSE 0.01
colorectal cancer KRAS_G12C NOTCH1 66 133 White -5.34 -12.13 -1.28 224.44 1.01 1763 66 133 0 TRUE 1.24
non-small cell lung cancer KRAS_G12C NOTCH1 20 11 Black -0.50 -1.62 0.79 47.99 1.05 169 19 10 1 TRUE 0.39
non-small cell lung cancer KRAS_G12C NOTCH1 419 108 White -0.50 -1.11 0.18 13.23 1.15 2499 408 97 11 TRUE 0.74
colorectal cancer KRAS_G12C NOTCH1 75 170 Race:overall -5.34 -12.28 -1.24 224.08 1.01 2187 75 170 0 TRUE 1.23
non-small cell lung cancer KRAS_G12C NOTCH1 439 119 Race:overall -0.50 -1.55 0.71 38.30 1.05 2668 427 107 12 TRUE 0.40
colorectal cancer KRAS_G12C NTRK1 58 46 White -4.62 -13.46 -0.40 32.10 1.05 1639 58 46 0 TRUE 0.71
non-small cell lung cancer KRAS_G12C NTRK1 405 75 White 0.34 -0.30 0.90 803.24 1.00 2453 391 61 14 TRUE 0.57
colorectal cancer KRAS_G12C NTRK1 58 46 Race:overall -3.63 -11.11 2.51 1069.14 1.01 1639 58 46 0 TRUE 0.60
non-small cell lung cancer KRAS_G12C NTRK1 405 75 Race:overall 0.39 -3.76 4.82 1392.15 1.00 2453 391 61 14 TRUE 0.07
non-small cell lung cancer KRAS_G12C INPP4A 405 45 White 0.27 -0.53 0.99 1484.05 1.00 2476 397 37 8 FALSE 0.31
non-small cell lung cancer KRAS_G12C INPP4A 405 45 Race:overall 0.22 -4.55 4.50 1416.74 1.00 2476 397 37 8 FALSE 0.04
colorectal cancer KRAS_G12C CASP8 58 73 White -5.64 -15.23 -0.79 1420.93 1.00 1618 58 73 0 FALSE 0.81
colorectal cancer KRAS_G12C CASP8 58 73 Race:overall -4.07 -11.10 2.59 1501.71 1.00 1618 58 73 0 FALSE 0.61
colorectal cancer KRAS_G12C SETD2 58 89 White -5.83 -15.36 -1.01 1251.41 1.00 1608 58 89 0 FALSE 0.77
non-small cell lung cancer KRAS_G12C SETD2 12 20 Asian -1.25 -6.25 0.99 1525.56 1.00 301 12 20 0 FALSE 0.31
non-small cell lung cancer KRAS_G12C SETD2 409 185 White 0.08 -0.36 0.51 1384.99 1.00 2380 381 157 28 FALSE 0.15
colorectal cancer KRAS_G12C SETD2 58 89 Race:overall -4.04 -12.10 3.15 1473.32 1.00 1608 58 89 0 FALSE 0.57
non-small cell lung cancer KRAS_G12C SETD2 421 205 Race:overall -0.52 -3.71 1.59 1271.17 1.00 2681 393 177 28 FALSE 0.16
colorectal cancer KRAS_G12C PBRM1 58 77 White -6.22 -14.89 -0.74 126.88 1.03 1617 58 77 0 TRUE 0.72
non-small cell lung cancer KRAS_G12C PBRM1 405 95 White -0.14 -0.78 0.49 1044.20 1.00 2441 393 83 12 TRUE 0.19
colorectal cancer KRAS_G12C PBRM1 58 77 Race:overall -4.63 -13.28 3.04 52.67 1.07 1617 58 77 0 TRUE 0.58
non-small cell lung cancer KRAS_G12C PBRM1 405 95 Race:overall -0.12 -4.44 4.22 1559.05 1.00 2441 393 83 12 TRUE 0.02
colorectal cancer KRAS_G12C EPHA3 58 81 White -0.75 -2.65 0.53 598.22 1.01 1610 56 79 2 FALSE 0.47
non-small cell lung cancer KRAS_G12C EPHA3 19 19 Black 0.21 -0.82 0.94 1391.84 1.00 160 17 17 2 FALSE 0.19
non-small cell lung cancer KRAS_G12C EPHA3 15 13 Unknown 0.04 -1.38 0.86 1237.20 1.00 148 15 13 0 FALSE 0.02
non-small cell lung cancer KRAS_G12C EPHA3 411 199 White 0.40 0.05 0.75 1425.10 1.00 2364 371 159 40 FALSE 1.54
colorectal cancer KRAS_G12C EPHA3 63 104 Race:overall -0.83 -2.82 0.71 651.81 1.01 1865 61 102 2 FALSE 0.47
non-small cell lung cancer KRAS_G12C EPHA3 445 231 Race:overall 0.22 -0.72 0.85 1322.57 1.00 2672 403 189 42 FALSE 0.24
colorectal cancer KRAS_G12C KIT 66 38 White 0.72 -0.79 1.86 1464.18 1.00 1832 63 35 3 TRUE 0.54
non-small cell lung cancer KRAS_G12C KIT 418 69 White 0.66 0.17 1.22 129.11 1.02 2539 401 52 17 TRUE 2.11
colorectal cancer KRAS_G12C KIT 66 38 Race:overall 0.48 -4.70 4.92 1356.43 1.00 1832 63 35 3 TRUE 0.08
non-small cell lung cancer KRAS_G12C KIT 418 69 Race:overall 0.60 -3.35 4.31 1647.40 1.00 2539 401 52 17 TRUE 0.14
colorectal cancer KRAS_G12C KDR 66 55 White -0.21 -2.13 1.18 243.45 1.01 1818 64 53 2 TRUE 0.10
non-small cell lung cancer KRAS_G12C KDR 21 11 Black 0.28 -0.61 1.37 1376.97 1.00 170 19 9 2 TRUE 0.25
non-small cell lung cancer KRAS_G12C KDR 419 121 White 0.17 -0.29 0.61 1531.80 1.00 2493 400 102 19 TRUE 0.33
colorectal cancer KRAS_G12C KDR 66 55 Race:overall -0.20 -4.47 4.03 1372.48 1.00 1818 64 53 2 TRUE 0.04
non-small cell lung cancer KRAS_G12C KDR 440 132 Race:overall 0.25 -0.55 1.37 1463.05 1.00 2663 419 111 21 TRUE 0.22
colorectal cancer KRAS_G12C RICTOR 58 60 White -1.23 -4.08 0.69 970.18 1.00 1633 57 59 1 FALSE 0.49
non-small cell lung cancer KRAS_G12C RICTOR 405 58 White -0.39 -1.33 0.41 842.63 1.00 2463 399 52 6 FALSE 0.43
colorectal cancer KRAS_G12C RICTOR 58 60 Race:overall -1.08 -5.74 3.99 1391.37 1.00 1633 57 59 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C RICTOR 405 58 Race:overall -0.42 -4.71 3.66 1274.37 1.00 2463 399 52 6 FALSE 0.08
colorectal cancer KRAS_G12C RAD50 58 42 White -0.83 -3.76 1.01 1132.67 1.00 1647 57 41 1 FALSE 0.30
colorectal cancer KRAS_G12C RAD50 58 42 Race:overall -0.79 -5.83 4.18 1552.90 1.00 1647 57 41 1 FALSE 0.13
colorectal cancer KRAS_G12C CSF1R 66 41 White -5.91 -16.32 -0.22 640.38 1.00 1830 66 41 0 TRUE 0.37
non-small cell lung cancer KRAS_G12C CSF1R 418 59 White 0.32 -0.38 0.94 1463.25 1.00 2545 407 48 11 TRUE 0.45
colorectal cancer KRAS_G12C CSF1R 66 41 Race:overall -4.12 -11.91 3.08 999.37 1.00 1830 66 41 0 TRUE 0.57
non-small cell lung cancer KRAS_G12C CSF1R 418 59 Race:overall 0.17 -4.49 4.28 1529.59 1.00 2545 407 48 11 TRUE 0.03
non-small cell lung cancer KRAS_G12C PARK2 405 59 White -0.09 -0.91 0.62 1406.85 1.00 2461 397 51 8 FALSE 0.08
non-small cell lung cancer KRAS_G12C PARK2 405 59 Race:overall -0.01 -4.17 4.34 1512.42 1.00 2461 397 51 8 FALSE 0.00
non-small cell lung cancer KRAS_G12C NTRK2 406 56 White 0.38 -0.31 1.01 1302.18 1.00 2469 395 45 11 FALSE 0.58
non-small cell lung cancer KRAS_G12C NTRK2 406 56 Race:overall 0.32 -4.15 4.82 1483.51 1.00 2469 395 45 11 FALSE 0.06
colorectal cancer KRAS_G12C PTCH1 58 115 White -1.91 -4.65 -0.03 1174.01 1.00 1593 57 114 1 TRUE 0.97
non-small cell lung cancer KRAS_G12C PTCH1 405 46 White 0.35 -0.46 1.09 857.53 1.00 2475 396 37 9 TRUE 0.42
colorectal cancer KRAS_G12C PTCH1 58 115 Race:overall -1.53 -6.35 3.78 1216.55 1.00 1593 57 114 1 TRUE 0.29
non-small cell lung cancer KRAS_G12C PTCH1 405 46 Race:overall 0.26 -4.27 4.52 1341.09 1.00 2475 396 37 9 TRUE 0.04
colorectal cancer KRAS_G12C TET1 58 76 White -1.41 -4.11 0.40 715.38 1.01 1621 57 75 1 FALSE 0.63
non-small cell lung cancer KRAS_G12C TET1 406 101 White 0.06 -0.51 0.62 1188.12 1.00 2431 391 86 15 FALSE 0.08
colorectal cancer KRAS_G12C TET1 58 76 Race:overall -1.13 -5.64 3.65 1509.20 1.00 1621 57 75 1 FALSE 0.22
non-small cell lung cancer KRAS_G12C TET1 406 101 Race:overall 0.07 -4.34 4.35 1318.69 1.00 2431 391 86 15 FALSE 0.01
colorectal cancer KRAS_G12C FGFR2 66 38 White -5.30 -14.68 -0.12 1325.91 1.00 1829 66 38 0 TRUE 0.75
colorectal cancer KRAS_G12C FGFR2 66 38 Race:overall -3.96 -11.42 2.72 1109.74 1.00 1829 66 38 0 TRUE 0.59
colorectal cancer KRAS_G12C TBX3 58 57 White -5.79 -15.71 -0.54 693.72 1.00 1634 58 57 0 FALSE 0.36
non-small cell lung cancer KRAS_G12C TBX3 405 114 White 0.23 -0.33 0.69 374.57 1.01 2426 386 95 19 FALSE 0.41
colorectal cancer KRAS_G12C TBX3 58 57 Race:overall -4.01 -11.58 2.54 1516.10 1.00 1634 58 57 0 FALSE 0.60
non-small cell lung cancer KRAS_G12C TBX3 405 114 Race:overall 0.20 -4.29 4.32 1579.10 1.00 2426 386 95 19 FALSE 0.04
colorectal cancer KRAS_G12C HNF1A 66 40 White -5.16 -15.30 -0.23 1231.39 1.00 1826 66 40 0 TRUE 0.70
colorectal cancer KRAS_G12C HNF1A 66 40 Race:overall -3.78 -11.38 3.15 1341.76 1.00 1826 66 40 0 TRUE 0.53
colorectal cancer KRAS_G12C DICER1 58 49 White -4.88 -12.43 -0.59 1133.67 1.00 1639 58 49 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C DICER1 405 69 White 0.24 -0.38 0.84 1179.88 1.00 2461 393 57 12 TRUE 0.35
colorectal cancer KRAS_G12C DICER1 60 61 Race:overall -4.58 -11.71 0.20 1108.34 1.00 1778 60 61 0 TRUE 0.87
non-small cell lung cancer KRAS_G12C DICER1 405 69 Race:overall 0.23 -4.01 4.74 1530.02 1.00 2461 393 57 12 TRUE 0.04
colorectal cancer KRAS_G12C SMAD3 58 84 White -1.73 -5.47 0.15 161.02 1.02 1612 57 83 1 TRUE 0.74
colorectal cancer KRAS_G12C SMAD3 60 98 Race:overall -1.73 -5.70 0.90 262.03 1.01 1747 59 97 1 TRUE 0.56
colorectal cancer KRAS_G12C NTRK3 58 60 White -1.18 -3.93 0.55 1438.07 1.00 1630 57 59 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C NTRK3 12 16 Asian 1.55 0.17 3.03 1459.90 1.00 305 9 13 3 FALSE 1.57
non-small cell lung cancer KRAS_G12C NTRK3 407 171 White 0.74 0.37 1.09 1395.60 1.00 2402 366 130 41 FALSE 4.31
colorectal cancer KRAS_G12C NTRK3 58 60 Race:overall -1.00 -5.58 4.22 1686.25 1.00 1630 57 59 1 FALSE 0.17
non-small cell lung cancer KRAS_G12C NTRK3 419 187 Race:overall 1.13 -0.69 3.08 1431.06 1.00 2707 375 143 44 FALSE 0.67
colorectal cancer KRAS_G12C AXIN1 58 57 White -5.66 -15.81 -0.41 1315.82 1.00 1632 58 57 0 FALSE 0.77
colorectal cancer KRAS_G12C AXIN1 58 57 Race:overall -4.08 -11.39 2.37 1431.48 1.00 1632 58 57 0 FALSE 0.61
colorectal cancer KRAS_G12C GRIN2A 58 107 White -0.28 -1.63 0.63 29.90 1.06 1588 55 104 3 FALSE 0.19
non-small cell lung cancer KRAS_G12C GRIN2A 408 171 White 0.04 -0.42 0.46 1179.58 1.00 2374 383 146 25 FALSE 0.07
colorectal cancer KRAS_G12C GRIN2A 60 118 Race:overall -0.38 -2.53 1.09 123.04 1.03 1727 57 115 3 FALSE 0.17
non-small cell lung cancer KRAS_G12C GRIN2A 408 171 Race:overall -0.04 -4.44 4.06 1336.07 1.00 2374 383 146 25 FALSE 0.01
colorectal cancer KRAS_G12C PALB2 58 44 White -5.46 -16.41 -0.19 1247.61 1.00 1641 58 44 0 TRUE 0.67
non-small cell lung cancer KRAS_G12C PALB2 405 47 White 0.45 -0.31 1.13 1311.82 1.00 2477 395 37 10 TRUE 0.66
colorectal cancer KRAS_G12C PALB2 58 44 Race:overall -3.91 -11.81 3.16 1291.81 1.00 1641 58 44 0 TRUE 0.54
non-small cell lung cancer KRAS_G12C PALB2 405 47 Race:overall 0.34 -3.96 4.39 1531.35 1.00 2477 395 37 10 TRUE 0.07
colorectal cancer KRAS_G12C CTCF 58 71 White -0.40 -2.12 0.92 1391.43 1.00 1624 56 69 2 FALSE 0.22
colorectal cancer KRAS_G12C CTCF 58 71 Race:overall -0.23 -4.83 5.09 1363.79 1.00 1624 56 69 2 FALSE 0.04
colorectal cancer KRAS_G12C CDH1 66 43 White -5.29 -14.89 -0.14 783.40 1.00 1829 66 43 0 TRUE 0.70
colorectal cancer KRAS_G12C CDH1 66 43 Race:overall -3.90 -11.21 2.76 645.86 1.00 1829 66 43 0 TRUE 0.60
colorectal cancer KRAS_G12C CDK12 59 76 White -0.48 -2.33 0.83 737.89 1.01 1622 57 74 2 FALSE 0.26
non-small cell lung cancer KRAS_G12C CDK12 405 45 White -0.64 -1.76 0.33 1288.39 1.00 2471 401 41 4 FALSE 0.61
colorectal cancer KRAS_G12C CDK12 59 76 Race:overall -0.34 -4.47 3.71 1389.85 1.00 1622 57 74 2 FALSE 0.07
non-small cell lung cancer KRAS_G12C CDK12 405 45 Race:overall -0.63 -5.21 4.00 1340.38 1.00 2471 401 41 4 FALSE 0.11
non-small cell lung cancer KRAS_G12C STK11 12 19 Asian 0.95 -0.18 2.00 1262.02 1.00 326 10 17 2 TRUE 1.10
non-small cell lung cancer KRAS_G12C STK11 20 30 Black 1.00 0.15 1.79 1594.31 1.00 155 14 24 6 TRUE 1.71
non-small cell lung cancer KRAS_G12C STK11 17 15 Unknown 0.89 -0.17 1.82 1325.52 1.00 150 14 12 3 TRUE 1.12
non-small cell lung cancer KRAS_G12C STK11 423 472 White 0.92 0.69 1.17 1488.93 1.00 2245 304 353 119 TRUE 12.95
non-small cell lung cancer KRAS_G12C STK11 472 536 Race:overall 0.94 0.15 1.68 1444.61 1.00 2876 342 406 130 TRUE 1.82
colorectal cancer KRAS_G12C DNMT1 58 71 White -5.65 -14.57 -0.52 938.08 1.00 1621 58 71 0 FALSE 0.59
colorectal cancer KRAS_G12C DNMT1 58 71 Race:overall -4.21 -12.25 2.31 774.09 1.00 1621 58 71 0 FALSE 0.61
colorectal cancer KRAS_G12C BRD4 59 69 White -0.41 -2.16 0.90 1402.09 1.00 1619 57 67 2 FALSE 0.22
non-small cell lung cancer KRAS_G12C BRD4 406 40 White 0.02 -0.91 0.86 1631.19 1.00 2479 400 34 6 FALSE 0.02
colorectal cancer KRAS_G12C BRD4 59 69 Race:overall -0.31 -4.20 4.13 1446.27 1.00 1619 57 67 2 FALSE 0.06
non-small cell lung cancer KRAS_G12C BRD4 406 40 Race:overall -0.03 -4.84 4.42 1678.05 1.00 2479 400 34 6 FALSE 0.00
colorectal cancer KRAS_G12C ASXL1 58 85 White -0.57 -2.30 0.68 1304.44 1.00 1608 56 83 2 TRUE 0.34
non-small cell lung cancer KRAS_G12C ASXL1 405 74 White -0.18 -0.97 0.45 973.64 1.00 2461 396 65 9 TRUE 0.22
colorectal cancer KRAS_G12C ASXL1 58 85 Race:overall -0.47 -4.46 4.69 1475.92 1.00 1608 56 83 2 TRUE 0.08
non-small cell lung cancer KRAS_G12C ASXL1 405 74 Race:overall -0.14 -4.16 3.81 1474.65 1.00 2461 396 65 9 TRUE 0.03
colorectal cancer KRAS_G12C EP300 58 107 White -5.47 -14.24 -1.19 852.49 1.01 1596 58 107 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C EP300 405 91 White -0.31 -1.02 0.33 1153.45 1.00 2441 395 81 10 TRUE 0.43
colorectal cancer KRAS_G12C EP300 58 107 Race:overall -4.37 -10.89 1.75 879.21 1.00 1596 58 107 0 TRUE 0.82
non-small cell lung cancer KRAS_G12C EP300 405 91 Race:overall -0.26 -4.39 4.17 1447.89 1.00 2441 395 81 10 TRUE 0.05
colorectal cancer KRAS_G12C ERBB4 66 109 White -1.00 -2.79 0.30 1565.86 1.00 1771 64 107 2 TRUE 0.69
non-small cell lung cancer KRAS_G12C ERBB4 20 17 Black -0.39 -1.49 0.88 1434.50 1.00 166 18 15 2 TRUE 0.29
non-small cell lung cancer KRAS_G12C ERBB4 419 160 White -0.67 -1.27 -0.08 457.01 1.00 2466 407 148 12 TRUE 1.58
colorectal cancer KRAS_G12C ERBB4 69 122 Race:overall -1.13 -3.61 0.65 1518.24 1.00 1887 67 120 2 TRUE 0.51
non-small cell lung cancer KRAS_G12C ERBB4 439 177 Race:overall -0.52 -1.63 0.79 1123.56 1.00 2632 425 163 14 TRUE 0.42
colorectal cancer KRAS_G12C MDC1 58 51 White -5.68 -14.54 -0.36 1137.03 1.01 1638 58 51 0 FALSE 0.78
non-small cell lung cancer KRAS_G12C MDC1 15 13 Unknown -1.22 -4.86 0.66 1435.10 1.00 151 15 13 0 FALSE 0.39
non-small cell lung cancer KRAS_G12C MDC1 408 73 White -0.03 -0.70 0.60 1254.18 1.00 2453 397 62 11 FALSE 0.03
colorectal cancer KRAS_G12C MDC1 58 51 Race:overall -4.56 -10.36 1.75 20.31 1.07 1638 58 51 0 FALSE 0.82
non-small cell lung cancer KRAS_G12C MDC1 423 86 Race:overall -0.60 -3.38 1.34 1445.11 1.00 2604 412 75 11 FALSE 0.21
colorectal cancer KRAS_G12C RECQL4 58 64 White -5.80 -16.01 -0.54 970.48 1.00 1626 58 64 0 TRUE 0.75
non-small cell lung cancer KRAS_G12C RECQL4 405 50 White -1.41 -3.25 0.05 29.96 1.10 2466 403 48 2 TRUE 0.96
colorectal cancer KRAS_G12C RECQL4 58 64 Race:overall -4.28 -12.10 2.40 841.74 1.00 1626 58 64 0 TRUE 0.62
non-small cell lung cancer KRAS_G12C RECQL4 405 50 Race:overall -1.18 -5.54 3.60 713.82 1.01 2466 403 48 2 TRUE 0.23
colorectal cancer KRAS_G12C MED12 59 95 White 0.63 -0.36 1.50 1225.26 1.00 1608 53 89 6 TRUE 0.72
non-small cell lung cancer KRAS_G12C MED12 407 146 White -0.10 -0.60 0.37 1236.43 1.00 2395 388 127 19 TRUE 0.17
colorectal cancer KRAS_G12C MED12 59 95 Race:overall 0.44 -3.99 4.77 1460.87 1.00 1608 53 89 6 TRUE 0.08
non-small cell lung cancer KRAS_G12C MED12 407 146 Race:overall -0.11 -4.46 4.02 1478.73 1.00 2395 388 127 19 TRUE 0.02
colorectal cancer KRAS_G12C ERCC5 58 46 White -0.95 -3.99 1.00 1031.06 1.00 1639 57 45 1 TRUE 0.34
non-small cell lung cancer KRAS_G12C ERCC5 405 57 White 0.37 -0.30 1.00 1388.75 1.00 2469 394 46 11 TRUE 0.55
colorectal cancer KRAS_G12C ERCC5 58 46 Race:overall -0.74 -5.73 4.48 1263.57 1.00 1639 57 45 1 TRUE 0.12
non-small cell lung cancer KRAS_G12C ERCC5 405 57 Race:overall 0.23 -4.29 4.38 1463.30 1.00 2469 394 46 11 TRUE 0.04
colorectal cancer KRAS_G12C PIK3CD 58 58 White -0.23 -2.04 1.14 1043.97 1.00 1632 56 56 2 FALSE 0.11
colorectal cancer KRAS_G12C PIK3CD 58 58 Race:overall -0.25 -4.62 4.00 1509.04 1.00 1632 56 56 2 FALSE 0.04
colorectal cancer KRAS_G12C BRCA1 58 56 White -5.37 -15.44 -0.42 1214.22 1.00 1633 58 56 0 TRUE 0.71
non-small cell lung cancer KRAS_G12C BRCA1 405 79 White 0.07 -0.57 0.65 1437.34 1.00 2449 393 67 12 TRUE 0.08
colorectal cancer KRAS_G12C BRCA1 58 56 Race:overall -3.82 -11.22 3.67 1340.76 1.00 1633 58 56 0 TRUE 0.55
non-small cell lung cancer KRAS_G12C BRCA1 405 79 Race:overall 0.02 -4.45 4.40 1477.65 1.00 2449 393 67 12 TRUE 0.00
colorectal cancer KRAS_G12C RBM10 58 54 White -5.63 -15.85 -0.54 1318.63 1.00 1633 58 54 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C RBM10 12 36 Asian 0.52 -0.42 1.42 1603.80 1.00 285 10 34 2 FALSE 0.60
non-small cell lung cancer KRAS_G12C RBM10 20 16 Black 0.80 -0.05 1.68 1383.70 1.00 163 16 12 4 FALSE 1.11
non-small cell lung cancer KRAS_G12C RBM10 15 15 Unknown 0.74 -0.18 1.69 1507.54 1.00 148 12 12 3 FALSE 0.92
non-small cell lung cancer KRAS_G12C RBM10 408 314 White 0.53 0.23 0.82 1583.82 1.00 2274 345 251 63 FALSE 3.32
colorectal cancer KRAS_G12C RBM10 58 54 Race:overall -4.08 -11.13 3.00 1437.07 1.00 1633 58 54 0 FALSE 0.61
non-small cell lung cancer KRAS_G12C RBM10 455 381 Race:overall 0.65 -0.07 1.39 1368.32 1.00 2870 383 309 72 FALSE 1.13
colorectal cancer KRAS_G12C TSC1 58 60 White -1.21 -3.87 0.74 1284.53 1.00 1635 57 59 1 TRUE 0.52
non-small cell lung cancer KRAS_G12C TSC1 405 44 White 0.44 -0.38 1.20 1321.62 1.00 2478 396 35 9 TRUE 0.57
colorectal cancer KRAS_G12C TSC1 58 60 Race:overall -0.92 -5.45 4.15 1448.72 1.00 1635 57 59 1 TRUE 0.16
non-small cell lung cancer KRAS_G12C TSC1 405 44 Race:overall 0.37 -4.18 5.30 1372.71 1.00 2478 396 35 9 TRUE 0.07
colorectal cancer KRAS_G12C FLCN 58 45 White -5.49 -16.32 -0.23 1358.90 1.00 1642 58 45 0 TRUE 0.74
colorectal cancer KRAS_G12C FLCN 58 45 Race:overall -3.97 -11.37 2.90 1114.53 1.00 1642 58 45 0 TRUE 0.58
colorectal cancer KRAS_G12C NF1 58 113 White -1.86 -4.69 -0.03 981.30 1.00 1598 57 112 1 TRUE 0.94
non-small cell lung cancer KRAS_G12C NF1 12 21 Asian -0.01 -1.12 1.27 1405.24 1.00 299 10 19 2 TRUE 0.00
non-small cell lung cancer KRAS_G12C NF1 19 18 Black -0.59 -2.07 0.52 1422.42 1.00 159 19 18 0 TRUE 0.44
non-small cell lung cancer KRAS_G12C NF1 15 14 Unknown -0.08 -1.20 1.10 1366.37 1.00 148 13 12 2 TRUE 0.05
non-small cell lung cancer KRAS_G12C NF1 408 254 White -0.40 -0.83 -0.02 1523.95 1.00 2321 383 229 25 TRUE 1.33
colorectal cancer KRAS_G12C NF1 58 113 Race:overall -1.50 -6.08 3.42 1006.99 1.00 1598 57 112 1 TRUE 0.30
non-small cell lung cancer KRAS_G12C NF1 454 307 Race:overall -0.27 -1.16 0.60 1572.68 1.00 2927 425 278 29 TRUE 0.26
colorectal cancer KRAS_G12C FLT1 58 68 White -5.91 -16.82 -0.66 1206.81 1.00 1626 58 68 0 FALSE 0.62
non-small cell lung cancer KRAS_G12C FLT1 408 118 White 0.44 -0.02 0.92 676.77 1.01 2426 384 94 24 FALSE 1.15
colorectal cancer KRAS_G12C FLT1 58 68 Race:overall -4.18 -11.77 2.80 1347.85 1.00 1626 58 68 0 FALSE 0.60
non-small cell lung cancer KRAS_G12C FLT1 408 118 Race:overall 0.40 -4.02 4.58 1597.92 1.00 2426 384 94 24 FALSE 0.08
colorectal cancer KRAS_G12C RPTOR 58 52 White -1.01 -3.70 0.72 1454.76 1.00 1634 57 51 1 FALSE 0.42
non-small cell lung cancer KRAS_G12C RPTOR 405 58 White -0.07 -0.88 0.64 1421.00 1.00 2464 397 50 8 FALSE 0.07
colorectal cancer KRAS_G12C RPTOR 58 52 Race:overall -0.80 -6.04 3.92 1651.41 1.00 1634 57 51 1 FALSE 0.13
non-small cell lung cancer KRAS_G12C RPTOR 405 58 Race:overall 0.00 -4.16 4.07 1313.46 1.00 2464 397 50 8 FALSE 0.00
colorectal cancer KRAS_G12C RASA1 58 58 White -1.15 -4.04 0.74 1454.62 1.00 1638 57 57 1 FALSE 0.47
non-small cell lung cancer KRAS_G12C RASA1 405 84 White -0.85 -1.85 -0.04 722.50 1.00 2435 399 78 6 FALSE 1.18
colorectal cancer KRAS_G12C RASA1 58 58 Race:overall -0.92 -5.42 3.73 1348.47 1.00 1638 57 57 1 FALSE 0.17
non-small cell lung cancer KRAS_G12C RASA1 405 84 Race:overall -0.71 -4.61 4.33 1487.52 1.00 2435 399 78 6 FALSE 0.14
colorectal cancer KRAS_G12C EPHA5 58 115 White -1.04 -2.82 0.24 1282.57 1.00 1585 56 113 2 FALSE 0.73
non-small cell lung cancer KRAS_G12C EPHA5 12 12 Asian 0.56 -0.64 1.65 1422.45 1.00 307 11 11 1 FALSE 0.47
non-small cell lung cancer KRAS_G12C EPHA5 19 18 Black 0.26 -0.87 1.21 1427.49 1.00 161 18 17 1 FALSE 0.21
non-small cell lung cancer KRAS_G12C EPHA5 15 12 Unknown 0.83 -0.19 1.86 1486.55 1.00 151 12 9 3 FALSE 0.94
non-small cell lung cancer KRAS_G12C EPHA5 407 213 White 0.67 0.33 0.99 1430.90 1.00 2365 358 164 49 FALSE 4.13
colorectal cancer KRAS_G12C EPHA5 63 138 Race:overall -1.11 -3.02 0.33 1267.16 1.00 1844 61 136 2 FALSE 0.70
non-small cell lung cancer KRAS_G12C EPHA5 453 255 Race:overall 0.59 -0.30 1.40 1497.49 1.00 2984 399 201 54 FALSE 0.78
colorectal cancer KRAS_G12C AR 58 86 White -5.46 -14.04 -0.76 141.41 1.02 1600 58 86 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C AR 19 13 Black -1.16 -5.66 0.83 1284.65 1.00 164 19 13 0 TRUE 0.29
non-small cell lung cancer KRAS_G12C AR 408 80 White 0.43 -0.16 0.95 1176.66 1.00 2451 391 63 17 TRUE 0.90
colorectal cancer KRAS_G12C AR 58 86 Race:overall -4.12 -12.99 3.14 137.69 1.03 1600 58 86 0 TRUE 0.57
non-small cell lung cancer KRAS_G12C AR 427 93 Race:overall -0.27 -3.26 1.66 1385.74 1.00 2615 410 76 17 TRUE 0.08
colorectal cancer KRAS_G12C GNAS 66 66 White -5.36 -15.56 -0.60 316.04 1.01 1804 66 66 0 TRUE 0.67
colorectal cancer KRAS_G12C GNAS 66 66 Race:overall -3.98 -11.40 2.73 741.57 1.01 1804 66 66 0 TRUE 0.57
colorectal cancer KRAS_G12C ASXL2 58 60 White -1.17 -3.87 0.63 1328.68 1.00 1641 57 59 1 FALSE 0.51
non-small cell lung cancer KRAS_G12C ASXL2 406 53 White 0.70 0.06 1.30 1348.76 1.00 2474 393 40 13 FALSE 1.60
colorectal cancer KRAS_G12C ASXL2 58 60 Race:overall -1.03 -5.69 3.76 1492.86 1.00 1641 57 59 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C ASXL2 406 53 Race:overall 0.53 -4.44 4.50 1299.16 1.00 2474 393 40 13 FALSE 0.10
colorectal cancer KRAS_G12C SF3B1 58 51 White -6.14 -12.55 -0.30 9.64 1.11 1640 58 51 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C SF3B1 405 71 White -1.47 -2.83 -0.37 1114.66 1.00 2447 402 68 3 TRUE 1.65
colorectal cancer KRAS_G12C SF3B1 58 51 Race:overall -5.48 -10.77 1.43 3.65 1.30 1640 58 51 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C SF3B1 405 71 Race:overall -1.20 -5.09 3.10 1467.37 1.00 2447 402 68 3 TRUE 0.27
colorectal cancer KRAS_G12C MLH1 66 49 White -5.46 -15.15 -0.47 414.12 1.01 1825 66 49 0 TRUE 0.43
colorectal cancer KRAS_G12C MLH1 66 49 Race:overall -3.96 -11.52 2.74 939.99 1.00 1825 66 49 0 TRUE 0.60
colorectal cancer KRAS_G12C ROS1 58 71 White -1.51 -4.18 0.35 1488.59 1.00 1618 57 70 1 TRUE 0.68
non-small cell lung cancer KRAS_G12C ROS1 406 93 White -0.78 -1.60 -0.06 1451.47 1.00 2430 399 86 7 TRUE 1.26
colorectal cancer KRAS_G12C ROS1 60 87 Race:overall -1.63 -5.02 1.10 1418.22 1.00 1755 59 86 1 TRUE 0.54
non-small cell lung cancer KRAS_G12C ROS1 406 93 Race:overall -0.59 -4.52 4.54 1420.99 1.00 2430 399 86 7 TRUE 0.11
colorectal cancer KRAS_G12C PIK3R2 58 36 White -6.29 -13.85 -0.18 20.98 1.06 1647 58 36 0 FALSE 0.94
colorectal cancer KRAS_G12C PIK3R2 58 36 Race:overall -5.22 -10.71 2.63 4.25 1.25 1647 58 36 0 FALSE 0.83
colorectal cancer KRAS_G12C FLT3 66 36 White -5.14 -14.32 -0.10 1408.50 1.00 1833 66 36 0 TRUE 0.71
non-small cell lung cancer KRAS_G12C FLT3 418 62 White 0.26 -0.52 0.91 1406.63 1.00 2543 407 51 11 TRUE 0.34
colorectal cancer KRAS_G12C FLT3 66 36 Race:overall -3.81 -11.35 3.14 1369.44 1.00 1833 66 36 0 TRUE 0.55
non-small cell lung cancer KRAS_G12C FLT3 418 62 Race:overall 0.28 -4.36 4.70 1493.20 1.00 2543 407 51 11 TRUE 0.05
colorectal cancer KRAS_G12C MSH2 58 63 White -1.25 -4.21 0.58 1157.94 1.00 1637 57 62 1 TRUE 0.50
non-small cell lung cancer KRAS_G12C MSH2 405 45 White -0.34 -1.36 0.63 761.64 1.00 2476 400 40 5 TRUE 0.31
colorectal cancer KRAS_G12C MSH2 58 63 Race:overall -1.00 -5.65 3.98 1380.54 1.00 1637 57 62 1 TRUE 0.18
non-small cell lung cancer KRAS_G12C MSH2 405 45 Race:overall -0.31 -4.68 4.13 1386.47 1.00 2476 400 40 5 TRUE 0.06
non-small cell lung cancer KRAS_G12C DIS3 405 53 White 0.58 -0.10 1.19 1370.34 1.00 2472 393 41 12 FALSE 1.08
non-small cell lung cancer KRAS_G12C DIS3 405 53 Race:overall 0.44 -4.11 4.64 1421.11 1.00 2472 393 41 12 FALSE 0.08
colorectal cancer KRAS_G12C AXL 58 67 White -1.30 -4.16 0.57 1417.86 1.00 1626 57 66 1 FALSE 0.56
colorectal cancer KRAS_G12C AXL 58 67 Race:overall -1.01 -5.68 4.37 1452.59 1.00 1626 57 66 1 FALSE 0.18
colorectal cancer KRAS_G12C PIK3CG 58 89 White -5.89 -15.65 -0.78 1074.34 1.00 1602 58 89 0 FALSE 0.82
non-small cell lung cancer KRAS_G12C PIK3CG 19 12 Black 0.07 -1.20 1.01 1463.31 1.00 165 18 11 1 FALSE 0.05
non-small cell lung cancer KRAS_G12C PIK3CG 408 151 White 0.20 -0.20 0.65 44.97 1.04 2399 382 125 26 FALSE 0.39
colorectal cancer KRAS_G12C PIK3CG 58 89 Race:overall -4.36 -11.48 2.66 1197.24 1.00 1602 58 89 0 FALSE 0.65
non-small cell lung cancer KRAS_G12C PIK3CG 427 163 Race:overall 0.14 -0.83 0.96 619.43 1.01 2564 400 136 27 FALSE 0.11
colorectal cancer KRAS_G12C MAP2K4 58 53 White -1.06 -3.67 0.78 1091.23 1.00 1632 57 52 1 TRUE 0.45
colorectal cancer KRAS_G12C MAP2K4 58 53 Race:overall -0.92 -5.78 3.64 1342.93 1.00 1632 57 52 1 TRUE 0.16
colorectal cancer KRAS_G12C EGFR 66 59 White -5.42 -15.41 -0.45 1205.35 1.00 1813 66 59 0 TRUE 0.77
non-small cell lung cancer KRAS_G12C EGFR 12 209 Asian -3.38 -5.03 -2.03 1393.19 1.00 163 12 209 0 TRUE 5.28
non-small cell lung cancer KRAS_G12C EGFR 20 69 Black -3.34 -5.08 -1.98 1467.09 1.00 125 20 69 0 TRUE 4.78
non-small cell lung cancer KRAS_G12C EGFR 17 52 Unknown -2.98 -4.47 -1.55 1340.57 1.00 117 16 51 1 TRUE 4.28
non-small cell lung cancer KRAS_G12C EGFR 418 694 White -2.99 -3.75 -2.32 1515.46 1.00 2033 410 686 8 TRUE 15.97
colorectal cancer KRAS_G12C EGFR 66 59 Race:overall -3.91 -11.36 3.17 1091.06 1.00 1813 66 59 0 TRUE 0.56
non-small cell lung cancer KRAS_G12C EGFR 471 1038 Race:overall -3.15 -4.30 -2.14 1320.63 1.00 2482 462 1029 9 TRUE 7.79
colorectal cancer KRAS_G12C ARID1B 58 121 White -5.95 -15.27 -1.15 1073.66 1.00 1581 58 121 0 TRUE 0.70
non-small cell lung cancer KRAS_G12C ARID1B 12 12 Asian -0.89 -5.25 1.34 1492.68 1.00 307 12 12 0 TRUE 0.22
non-small cell lung cancer KRAS_G12C ARID1B 405 82 White 0.18 -0.48 0.76 1532.77 1.00 2447 391 68 14 TRUE 0.25
colorectal cancer KRAS_G12C ARID1B 58 121 Race:overall -4.30 -11.72 2.45 963.67 1.00 1581 58 121 0 TRUE 0.66
non-small cell lung cancer KRAS_G12C ARID1B 417 94 Race:overall -0.33 -3.42 1.68 1352.76 1.00 2754 403 80 14 TRUE 0.10
non-small cell lung cancer KRAS_G12C INSR 405 48 White -0.67 -1.85 0.29 1192.15 1.00 2471 401 44 4 FALSE 0.64
non-small cell lung cancer KRAS_G12C INSR 405 48 Race:overall -0.47 -4.47 4.07 1649.75 1.00 2471 401 44 4 FALSE 0.09
non-small cell lung cancer KRAS_G12C NKX2-1 408 58 White 0.65 -0.01 1.22 1521.83 1.00 2473 394 44 14 TRUE 1.37
non-small cell lung cancer KRAS_G12C NKX2-1 408 58 Race:overall 0.57 -3.67 4.84 1541.40 1.00 2473 394 44 14 TRUE 0.11
colorectal cancer KRAS_G12C ARID5B 58 53 White -5.49 -14.61 -0.37 1049.35 1.00 1643 58 53 0 FALSE 0.72
colorectal cancer KRAS_G12C ARID5B 58 53 Race:overall -4.03 -12.09 2.71 1043.00 1.00 1643 58 53 0 FALSE 0.58
non-small cell lung cancer KRAS_G12C WT1 405 60 White -0.96 -2.11 -0.06 1025.68 1.00 2459 401 56 4 TRUE 1.13
non-small cell lung cancer KRAS_G12C WT1 405 60 Race:overall -0.74 -4.57 4.33 1412.54 1.00 2459 401 56 4 TRUE 0.15
non-small cell lung cancer KRAS_G12C MET 12 13 Asian -0.20 -2.44 1.88 1495.86 1.00 328 11 12 1 TRUE 0.07
non-small cell lung cancer KRAS_G12C MET 418 140 White -1.14 -1.95 -0.46 1322.77 1.00 2470 411 133 7 TRUE 2.51
non-small cell lung cancer KRAS_G12C MET 430 153 Race:overall -0.67 -2.83 1.72 1555.41 1.00 2798 422 145 8 TRUE 0.26
non-small cell lung cancer KRAS_G12C PMS1 405 44 White -0.11 -1.07 0.71 1372.66 1.00 2475 399 38 6 TRUE 0.09
non-small cell lung cancer KRAS_G12C PMS1 405 44 Race:overall -0.14 -4.33 4.25 1213.96 1.00 2475 399 38 6 TRUE 0.02
non-small cell lung cancer KRAS_G12C PIK3C3 405 62 White -0.71 -1.75 0.16 1415.72 1.00 2457 400 57 5 FALSE 0.84
non-small cell lung cancer KRAS_G12C PIK3C3 405 62 Race:overall -0.56 -4.60 3.80 1364.71 1.00 2457 400 57 5 FALSE 0.11
colorectal cancer KRAS_G12C BRAF 66 207 White -5.80 -11.68 -1.88 27.11 1.11 1669 66 207 0 TRUE 1.48
non-small cell lung cancer KRAS_G12C BRAF 418 167 White -1.59 -2.47 -0.86 1284.59 1.00 2433 412 161 6 TRUE 3.64
colorectal cancer KRAS_G12C BRAF 75 249 Race:overall -5.79 -11.48 -1.86 27.36 1.10 2079 75 249 0 TRUE 1.47
non-small cell lung cancer KRAS_G12C BRAF 418 167 Race:overall -1.36 -5.82 3.31 1454.78 1.00 2433 412 161 6 TRUE 0.28
colorectal cancer KRAS_G12C B2M 59 102 White -0.44 -1.82 0.70 517.27 1.01 1620 56 99 3 FALSE 0.30
colorectal cancer KRAS_G12C B2M 64 129 Race:overall -0.55 -2.40 0.82 883.29 1.00 1877 61 126 3 FALSE 0.30
colorectal cancer KRAS_G12C TGFBR1 58 33 White -0.58 -3.33 1.25 913.20 1.00 1654 57 32 1 FALSE 0.20
non-small cell lung cancer KRAS_G12C TGFBR1 405 37 White 0.80 0.04 1.50 1488.41 1.00 2485 395 27 10 FALSE 1.44
colorectal cancer KRAS_G12C TGFBR1 58 33 Race:overall -0.48 -5.17 4.28 1121.64 1.00 1654 57 32 1 FALSE 0.08
non-small cell lung cancer KRAS_G12C TGFBR1 405 37 Race:overall 0.67 -4.01 4.94 1326.49 1.00 2485 395 27 10 FALSE 0.13
colorectal cancer KRAS_G12C TET2 58 67 White -5.82 -15.84 -0.74 1197.03 1.00 1627 58 67 0 TRUE 0.78
non-small cell lung cancer KRAS_G12C TET2 405 66 White -0.56 -1.45 0.21 1483.86 1.00 2457 399 60 6 TRUE 0.71
colorectal cancer KRAS_G12C TET2 58 67 Race:overall -4.34 -11.89 2.14 1028.21 1.00 1627 58 67 0 TRUE 0.64
non-small cell lung cancer KRAS_G12C TET2 405 66 Race:overall -0.47 -4.82 4.14 1418.52 1.00 2457 399 60 6 TRUE 0.08
colorectal cancer KRAS_G12C PDGFRB 58 38 White -0.72 -3.50 1.20 1276.77 1.00 1646 57 37 1 TRUE 0.26
non-small cell lung cancer KRAS_G12C PDGFRB 407 82 White 0.12 -0.53 0.69 1351.49 1.00 2448 394 69 13 TRUE 0.15
colorectal cancer KRAS_G12C PDGFRB 58 38 Race:overall -0.51 -5.26 4.55 1404.35 1.00 1646 57 37 1 TRUE 0.08
non-small cell lung cancer KRAS_G12C PDGFRB 407 82 Race:overall 0.09 -4.19 4.11 1401.55 1.00 2448 394 69 13 TRUE 0.02
colorectal cancer KRAS_G12C CARD11 58 106 White -0.01 -1.16 0.96 427.84 1.00 1591 54 102 4 FALSE 0.01
non-small cell lung cancer KRAS_G12C CARD11 406 100 White 0.24 -0.33 0.71 766.48 1.00 2434 389 83 17 FALSE 0.43
colorectal cancer KRAS_G12C CARD11 58 106 Race:overall -0.09 -4.27 4.06 1395.37 1.00 1591 54 102 4 FALSE 0.02
non-small cell lung cancer KRAS_G12C CARD11 406 100 Race:overall 0.18 -4.12 4.88 1542.75 1.00 2434 389 83 17 FALSE 0.03
colorectal cancer KRAS_G12C DNMT3A 58 40 White -5.11 -14.19 -0.24 1117.68 1.00 1646 58 40 0 TRUE 0.77
non-small cell lung cancer KRAS_G12C DNMT3A 405 66 White 0.50 -0.14 1.07 1470.29 1.00 2461 391 52 14 TRUE 0.94
colorectal cancer KRAS_G12C DNMT3A 58 40 Race:overall -3.81 -11.56 2.82 997.98 1.00 1646 58 40 0 TRUE 0.54
non-small cell lung cancer KRAS_G12C DNMT3A 405 66 Race:overall 0.53 -4.02 4.89 1516.22 1.00 2461 391 52 14 TRUE 0.10
colorectal cancer KRAS_G12C MSH6 58 83 White -5.87 -15.00 -0.86 1286.74 1.00 1615 58 83 0 TRUE 0.84
colorectal cancer KRAS_G12C MSH6 58 83 Race:overall -4.21 -11.51 2.89 1368.84 1.00 1615 58 83 0 TRUE 0.61
non-small cell lung cancer KRAS_G12C MAX 406 46 White 0.53 -0.20 1.20 1118.08 1.00 2476 396 36 10 FALSE 0.83
non-small cell lung cancer KRAS_G12C MAX 406 46 Race:overall 0.50 -3.85 4.98 1385.83 1.00 2476 396 36 10 FALSE 0.10
non-small cell lung cancer KRAS_G12C INPP4B 407 111 White 0.65 0.19 1.09 1171.93 1.00 2434 381 85 26 FALSE 2.41
non-small cell lung cancer KRAS_G12C INPP4B 407 111 Race:overall 0.53 -3.73 4.21 1410.01 1.00 2434 381 85 26 FALSE 0.11
non-small cell lung cancer KRAS_G12C NFE2L2 406 101 White -0.46 -1.13 0.18 259.25 1.01 2429 396 91 10 FALSE 0.78
non-small cell lung cancer KRAS_G12C NFE2L2 406 101 Race:overall -0.40 -4.18 3.71 1555.52 1.00 2429 396 91 10 FALSE 0.08
colorectal cancer KRAS_G12C SOX9 60 209 White 0.02 -0.76 0.74 784.63 1.01 1499 52 201 8 FALSE 0.02
colorectal cancer KRAS_G12C SOX9 64 245 Race:overall -0.08 -1.38 0.94 1103.27 1.00 1760 56 237 8 FALSE 0.05
colorectal cancer KRAS_G12C ETV1 58 44 White -5.37 -16.18 -0.26 1083.62 1.00 1642 58 44 0 TRUE 0.67
colorectal cancer KRAS_G12C ETV1 58 44 Race:overall -3.97 -11.55 3.59 1472.79 1.00 1642 58 44 0 TRUE 0.54
colorectal cancer KRAS_G12C ARAF 58 50 White -0.99 -3.73 0.82 949.12 1.00 1639 57 49 1 FALSE 0.38
non-small cell lung cancer KRAS_G12C ARAF 406 52 White 0.09 -0.75 0.77 317.25 1.01 2472 398 44 8 FALSE 0.08
colorectal cancer KRAS_G12C ARAF 58 50 Race:overall -0.81 -5.69 4.15 932.05 1.00 1639 57 49 1 FALSE 0.14
non-small cell lung cancer KRAS_G12C ARAF 406 52 Race:overall 0.13 -4.35 4.38 1377.76 1.00 2472 398 44 8 FALSE 0.02
non-small cell lung cancer KRAS_G12C JAK2 418 62 White -0.69 -1.77 0.18 1374.84 1.00 2536 413 57 5 TRUE 0.78
non-small cell lung cancer KRAS_G12C JAK2 418 62 Race:overall -0.61 -5.16 4.06 1554.02 1.00 2536 413 57 5 TRUE 0.11
colorectal cancer KRAS_G12C SMAD2 58 74 White 0.25 -0.72 1.35 8.28 1.20 1623 54 70 4 TRUE 0.17
colorectal cancer KRAS_G12C SMAD2 58 74 Race:overall 0.19 -3.69 4.42 334.10 1.02 1623 54 70 4 TRUE 0.04
non-small cell lung cancer KRAS_G12C TP63 405 63 White -0.33 -1.20 0.44 1360.05 1.00 2458 398 56 7 FALSE 0.37
non-small cell lung cancer KRAS_G12C TP63 405 63 Race:overall -0.25 -4.25 4.42 1473.41 1.00 2458 398 56 7 FALSE 0.04
colorectal cancer KRAS_G12C JUN 58 41 White -5.63 -14.87 -0.29 1223.15 1.00 1645 58 41 0 FALSE 0.70
colorectal cancer KRAS_G12C JUN 58 41 Race:overall -4.12 -11.62 2.72 848.50 1.00 1645 58 41 0 FALSE 0.60
colorectal cancer KRAS_G12C DNMT3B 58 46 White -5.22 -15.36 -0.44 607.52 1.01 1644 58 46 0 FALSE 0.68
colorectal cancer KRAS_G12C DNMT3B 58 46 Race:overall -3.79 -10.90 2.90 1228.31 1.00 1644 58 46 0 FALSE 0.57
non-small cell lung cancer KRAS_G12C MYOD1 405 46 White -0.46 -1.31 0.41 30.67 1.05 2475 400 41 5 FALSE 0.57
non-small cell lung cancer KRAS_G12C MYOD1 405 46 Race:overall -0.48 -4.08 3.22 1525.15 1.00 2475 400 41 5 FALSE 0.12
colorectal cancer KRAS_G12C FGFR1 66 37 White -5.31 -14.89 -0.05 1118.69 1.00 1833 66 37 0 TRUE 0.69
colorectal cancer KRAS_G12C FGFR1 66 37 Race:overall -3.74 -11.78 2.79 1348.55 1.00 1833 66 37 0 TRUE 0.52
colorectal cancer KRAS_G12C MITF 58 42 White 0.65 -1.06 1.80 333.82 1.01 1643 55 39 3 FALSE 0.47
colorectal cancer KRAS_G12C MITF 58 42 Race:overall 0.55 -4.11 4.98 983.51 1.00 1643 55 39 3 FALSE 0.10
non-small cell lung cancer KRAS_G12C BTK 405 49 White 0.30 -0.48 0.95 1370.13 1.00 2473 396 40 9 TRUE 0.37
non-small cell lung cancer KRAS_G12C BTK 405 49 Race:overall 0.23 -4.57 4.75 1398.38 1.00 2473 396 40 9 TRUE 0.04
colorectal cancer KRAS_G12C SH2B3 51 41 White -5.09 -13.59 -0.23 1272.71 1.00 1495 51 41 0 FALSE 0.71
colorectal cancer KRAS_G12C SH2B3 51 41 Race:overall -3.66 -10.97 2.73 1339.07 1.00 1495 51 41 0 FALSE 0.56
colorectal cancer KRAS_G12C GLI1 51 65 White -4.60 -11.96 -0.52 404.97 1.01 1473 51 65 0 FALSE 0.91
non-small cell lung cancer KRAS_G12C GLI1 375 90 White 0.48 -0.05 0.97 908.75 1.00 2180 356 71 19 FALSE 1.16
colorectal cancer KRAS_G12C GLI1 53 76 Race:overall -4.40 -11.31 -0.10 488.30 1.01 1599 53 76 0 FALSE 0.88
non-small cell lung cancer KRAS_G12C GLI1 375 90 Race:overall 0.36 -4.27 4.67 1304.02 1.00 2180 356 71 19 FALSE 0.07
colorectal cancer KRAS_G12C ZFHX3 51 183 White -2.38 -5.02 -0.59 212.51 1.01 1402 50 182 1 FALSE 1.34
non-small cell lung cancer KRAS_G12C ZFHX3 17 11 Black -0.20 -1.45 0.88 1348.71 1.00 152 16 10 1 FALSE 0.15
non-small cell lung cancer KRAS_G12C ZFHX3 374 136 White -0.17 -0.71 0.28 1112.26 1.01 2132 357 119 17 FALSE 0.29
colorectal cancer KRAS_G12C ZFHX3 56 216 Race:overall -2.38 -5.17 -0.48 220.16 1.02 1633 55 215 1 FALSE 1.27
non-small cell lung cancer KRAS_G12C ZFHX3 391 147 Race:overall -0.19 -1.25 0.72 882.59 1.00 2284 373 129 18 FALSE 0.15
colorectal cancer KRAS_G12C MST1R 51 60 White -5.27 -14.94 -0.63 1083.98 1.00 1484 51 60 0 FALSE 0.71
colorectal cancer KRAS_G12C MST1R 51 60 Race:overall -3.88 -10.95 2.82 1465.95 1.00 1484 51 60 0 FALSE 0.57
colorectal cancer KRAS_G12C MGA 51 99 White -0.75 -2.59 0.59 1096.01 1.00 1446 49 97 2 FALSE 0.46
non-small cell lung cancer KRAS_G12C MGA 12 15 Asian 0.90 -0.60 2.34 1394.54 1.00 271 10 13 2 FALSE 0.63
non-small cell lung cancer KRAS_G12C MGA 377 163 White 0.43 0.04 0.81 1430.53 1.00 2135 345 131 32 FALSE 1.51
colorectal cancer KRAS_G12C MGA 51 99 Race:overall -0.66 -4.69 4.17 1393.89 1.00 1446 49 97 2 FALSE 0.12
non-small cell lung cancer KRAS_G12C MGA 389 178 Race:overall 0.66 -1.11 2.77 1261.71 1.00 2406 355 144 34 FALSE 0.31
colorectal cancer KRAS_G12C TCF3 51 60 White -5.34 -14.90 -0.42 1056.23 1.00 1477 51 60 0 FALSE 0.76
colorectal cancer KRAS_G12C TCF3 51 60 Race:overall -3.98 -11.28 2.66 1335.96 1.00 1477 51 60 0 FALSE 0.58
non-small cell lung cancer KRAS_G12C KMT2B 209 59 White 0.33 -0.35 0.97 1391.25 1.00 1222 198 48 11 FALSE 0.48
non-small cell lung cancer KRAS_G12C KMT2B 209 59 Race:overall 0.26 -4.03 4.60 1395.04 1.00 1222 198 48 11 FALSE 0.05
colorectal cancer KRAS_G12C TCF7L2 51 239 White 0.04 -0.70 0.72 928.96 1.00 1322 42 230 9 FALSE 0.04
colorectal cancer KRAS_G12C TCF7L2 58 294 Race:overall -0.08 -1.13 0.74 986.91 1.00 1655 49 285 9 FALSE 0.06
colorectal cancer KRAS_G12C ANKRD11 51 125 White -6.10 -16.06 -1.10 1254.88 1.00 1435 51 125 0 FALSE 0.84
non-small cell lung cancer KRAS_G12C ANKRD11 373 64 White -0.54 -1.55 0.26 1459.87 1.00 2192 367 58 6 FALSE 0.62
colorectal cancer KRAS_G12C ANKRD11 51 125 Race:overall -4.45 -11.72 2.65 1379.51 1.00 1435 51 125 0 FALSE 0.66
non-small cell lung cancer KRAS_G12C ANKRD11 373 64 Race:overall -0.46 -4.85 4.13 1556.54 1.00 2192 367 58 6 FALSE 0.09
colorectal cancer KRAS_G12C PGR 51 52 White -4.75 -14.91 0.02 36.83 1.09 1484 51 52 0 FALSE 0.54
non-small cell lung cancer KRAS_G12C PGR 17 13 Black 0.54 -0.83 1.70 1351.22 1.00 151 15 11 2 FALSE 0.40
non-small cell lung cancer KRAS_G12C PGR 374 63 White 0.60 -0.04 1.16 1315.87 1.00 2200 359 48 15 FALSE 1.29
colorectal cancer KRAS_G12C PGR 51 52 Race:overall -3.49 -11.16 2.06 50.88 1.07 1484 51 52 0 FALSE 0.50
non-small cell lung cancer KRAS_G12C PGR 391 76 Race:overall 0.58 -0.86 2.11 1496.91 1.00 2351 374 59 17 FALSE 0.33
colorectal cancer KRAS_G12C PLCG2 51 64 White -1.25 -3.90 0.63 1340.57 1.00 1475 50 63 1 FALSE 0.54
non-small cell lung cancer KRAS_G12C PLCG2 373 52 White -0.15 -0.94 0.64 523.90 1.02 2208 366 45 7 FALSE 0.15
colorectal cancer KRAS_G12C PLCG2 51 64 Race:overall -1.04 -5.70 3.81 1441.36 1.00 1475 50 63 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C PLCG2 373 52 Race:overall -0.06 -4.13 4.63 1261.14 1.00 2208 366 45 7 FALSE 0.01
colorectal cancer KRAS_G12C POLD1 51 95 White -1.54 -4.33 0.20 1316.21 1.00 1463 50 94 1 TRUE 0.72
non-small cell lung cancer KRAS_G12C POLD1 373 49 White -0.74 -1.86 0.16 1226.13 1.00 2203 369 45 4 TRUE 0.78
colorectal cancer KRAS_G12C POLD1 51 95 Race:overall -1.25 -5.85 3.64 1355.68 1.00 1463 50 94 1 TRUE 0.24
non-small cell lung cancer KRAS_G12C POLD1 373 49 Race:overall -0.63 -5.15 3.87 1520.89 1.00 2203 369 45 4 TRUE 0.12
colorectal cancer KRAS_G12C INHBA 51 43 White -0.78 -3.44 1.03 1471.97 1.00 1490 50 42 1 FALSE 0.30
non-small cell lung cancer KRAS_G12C INHBA 373 75 White 0.20 -0.46 0.76 949.65 1.00 2191 360 62 13 FALSE 0.28
colorectal cancer KRAS_G12C INHBA 51 43 Race:overall -0.72 -5.49 3.58 1371.84 1.00 1490 50 42 1 FALSE 0.13
non-small cell lung cancer KRAS_G12C INHBA 373 75 Race:overall 0.04 -4.61 3.99 1348.37 1.00 2191 360 62 13 FALSE 0.01
non-small cell lung cancer KRAS_G12C PREX2 9 12 Black -0.82 -5.08 0.94 1144.30 1.00 90 9 12 0 FALSE 0.22
non-small cell lung cancer KRAS_G12C PREX2 210 86 White 0.33 -0.26 0.87 1391.72 1.00 1203 193 69 17 FALSE 0.60
non-small cell lung cancer KRAS_G12C PREX2 219 98 Race:overall -0.21 -3.08 1.43 1394.86 1.00 1293 202 81 17 FALSE 0.07
colorectal cancer KRAS_G12C AMER1 58 135 White 0.23 -0.80 0.99 1277.45 1.00 1566 52 129 6 FALSE 0.21
non-small cell lung cancer KRAS_G12C AMER1 19 16 Black 0.98 0.06 2.06 1457.20 1.00 167 15 12 4 FALSE 1.31
non-small cell lung cancer KRAS_G12C AMER1 407 127 White 0.70 0.29 1.07 1418.23 1.00 2430 377 97 30 FALSE 3.33
colorectal cancer KRAS_G12C AMER1 60 147 Race:overall 0.11 -1.76 1.59 1351.20 1.00 1700 54 141 6 FALSE 0.05
non-small cell lung cancer KRAS_G12C AMER1 426 143 Race:overall 0.87 -0.24 2.10 1514.93 1.00 2597 392 109 34 FALSE 0.80
colorectal cancer KRAS_G12C HLA-A 51 45 White -5.15 -14.88 -0.05 1243.70 1.00 1494 51 45 0 FALSE 0.63
colorectal cancer KRAS_G12C HLA-A 51 45 Race:overall -3.58 -11.31 3.53 1341.14 1.00 1494 51 45 0 FALSE 0.49
colorectal cancer KRAS_G12C EPHA7 51 69 White -5.63 -14.85 -0.68 1358.96 1.00 1472 51 69 0 FALSE 0.81
non-small cell lung cancer KRAS_G12C EPHA7 373 110 White -0.09 -0.70 0.46 765.28 1.00 2158 358 95 15 FALSE 0.12
colorectal cancer KRAS_G12C EPHA7 51 69 Race:overall -4.17 -11.00 2.12 1063.89 1.00 1472 51 69 0 FALSE 0.67
non-small cell lung cancer KRAS_G12C EPHA7 373 110 Race:overall -0.11 -4.90 4.47 1549.90 1.00 2158 358 95 15 FALSE 0.02
colorectal cancer KRAS_G12C NCOA3 51 45 White -0.87 -3.66 1.00 1136.28 1.00 1491 50 44 1 TRUE 0.32
colorectal cancer KRAS_G12C NCOA3 51 45 Race:overall -0.78 -5.83 3.76 1293.65 1.00 1491 50 44 1 TRUE 0.14
non-small cell lung cancer KRAS_G12C DROSHA 209 42 White -0.04 -1.06 0.84 697.19 1.00 1231 203 36 6 FALSE 0.03
non-small cell lung cancer KRAS_G12C DROSHA 209 42 Race:overall -0.02 -4.25 4.31 1505.88 1.00 1231 203 36 6 FALSE 0.00
cancer of unknown primary KRAS_G12D SPEN 41 49 White -0.01 -1.12 1.05 48.16 1.07 524 37 45 4 FALSE 0.01
colorectal cancer KRAS_G12D SPEN 27 11 Black -0.05 -1.25 0.83 1116.17 1.00 113 25 9 2 FALSE 0.04
colorectal cancer KRAS_G12D SPEN 216 121 White -0.02 -0.54 0.50 1151.51 1.00 1451 201 106 15 FALSE 0.02
non-small cell lung cancer KRAS_G12D SPEN 123 101 White -2.02 -5.41 -0.09 292.75 1.01 2724 122 100 1 FALSE 0.93
uterine cancer KRAS_G12D SPEN 41 91 White 0.70 -0.11 1.45 1119.17 1.00 709 32 82 9 FALSE 1.10
cancer of unknown primary KRAS_G12D SPEN 41 49 Race:overall -0.11 -4.32 3.77 1323.96 1.00 524 37 45 4 FALSE 0.02
colorectal cancer KRAS_G12D SPEN 243 132 Race:overall -0.04 -1.12 1.01 1234.42 1.00 1564 226 115 17 FALSE 0.03
non-small cell lung cancer KRAS_G12D SPEN 123 101 Race:overall -1.76 -6.51 3.29 956.43 1.00 2724 122 100 1 FALSE 0.34
uterine cancer KRAS_G12D SPEN 45 107 Race:overall 0.10 -2.85 1.80 1144.81 1.00 767 36 98 9 FALSE 0.03
colorectal cancer KRAS_G12D KMT2C 22 14 Asian -0.14 -0.77 0.52 1184.71 1.00 121 20 12 2 FALSE 0.17
colorectal cancer KRAS_G12D KMT2C 29 12 Black -0.11 -0.71 0.50 1241.59 1.00 114 26 9 3 FALSE 0.13
colorectal cancer KRAS_G12D KMT2C 19 11 Unknown -0.13 -0.77 0.53 1374.54 1.00 104 17 9 2 FALSE 0.17
colorectal cancer KRAS_G12D KMT2C 217 157 White -0.21 -0.71 0.25 1320.62 1.00 1425 202 142 15 FALSE 0.40
non-small cell lung cancer KRAS_G12D KMT2C 8 14 Asian -0.84 -2.53 0.41 1240.87 1.00 307 8 14 0 FALSE 0.56
non-small cell lung cancer KRAS_G12D KMT2C 11 11 Black -0.84 -2.46 0.38 1309.13 1.00 172 11 11 0 FALSE 0.60
non-small cell lung cancer KRAS_G12D KMT2C 123 185 White -0.66 -1.73 0.21 1051.71 1.00 2630 118 180 5 FALSE 0.76
colorectal cancer KRAS_G12D KMT2C 287 194 Race:overall -0.15 -0.73 0.38 1312.78 1.00 1764 265 172 22 FALSE 0.22
non-small cell lung cancer KRAS_G12D KMT2C 142 210 Race:overall -0.77 -2.18 0.38 1280.66 1.00 3109 137 205 5 FALSE 0.63
appendiceal cancer KRAS_G12D TP53 45 41 White 0.09 -0.68 0.90 643.06 1.00 78 32 28 13 TRUE 0.09
cancer of unknown primary KRAS_G12D TP53 41 334 White 0.26 -0.28 0.85 1307.21 1.00 295 15 308 26 TRUE 0.45
colorectal cancer KRAS_G12D TP53 27 124 Asian -0.44 -0.91 0.08 1407.01 1.00 52 12 109 15 TRUE 1.17
colorectal cancer KRAS_G12D TP53 32 117 Black -0.35 -0.80 0.14 1415.43 1.00 32 12 97 20 TRUE 0.85
colorectal cancer KRAS_G12D TP53 9 26 Race:Other -0.32 -0.84 0.31 1556.00 1.00 24 3 20 6 TRUE 0.58
colorectal cancer KRAS_G12D TP53 19 96 Unknown -0.34 -0.80 0.22 1458.41 1.00 29 5 82 14 TRUE 0.74
colorectal cancer KRAS_G12D TP53 264 1350 White -0.53 -0.79 -0.27 1456.95 1.00 565 119 1205 145 TRUE 4.54
non-small cell lung cancer KRAS_G12D TP53 8 173 Asian -0.87 -1.45 -0.18 1402.94 1.00 182 4 169 4 TRUE 2.11
non-small cell lung cancer KRAS_G12D TP53 11 128 Black -0.91 -1.52 -0.32 1483.20 1.00 73 7 124 4 TRUE 2.50
non-small cell lung cancer KRAS_G12D TP53 9 98 Unknown -0.85 -1.45 -0.15 1347.12 1.00 85 5 94 4 TRUE 2.08
non-small cell lung cancer KRAS_G12D TP53 128 1617 White -1.02 -1.39 -0.65 1143.64 1.00 1414 94 1583 34 TRUE 7.10
pancreatic cancer KRAS_G12D TP53 19 44 Asian 0.87 0.41 1.22 1311.25 1.00 29 7 32 12 TRUE 4.92
pancreatic cancer KRAS_G12D TP53 18 39 Black 0.95 0.59 1.33 1494.43 1.00 13 3 24 15 TRUE 6.33
pancreatic cancer KRAS_G12D TP53 11 19 Race:Other 0.93 0.52 1.30 1617.02 1.00 7 4 12 7 TRUE 5.70
pancreatic cancer KRAS_G12D TP53 27 50 Unknown 0.97 0.63 1.34 1429.30 1.00 27 5 28 22 TRUE 6.95
pancreatic cancer KRAS_G12D TP53 419 792 White 0.96 0.72 1.21 1372.89 1.00 393 99 472 320 TRUE 14.26
uterine cancer KRAS_G12D TP53 39 388 White -1.18 -1.94 -0.50 1452.06 1.00 497 32 381 7 TRUE 2.99
appendiceal cancer KRAS_G12D TP53 45 41 Race:overall 0.08 -4.10 3.99 1610.89 1.00 78 32 28 13 TRUE 0.01
cancer of unknown primary KRAS_G12D TP53 49 409 Race:overall 0.11 -0.81 0.78 722.18 1.01 357 21 381 28 TRUE 0.11
colorectal cancer KRAS_G12D TP53 351 1713 Race:overall -0.39 -0.76 0.03 1500.14 1.00 702 151 1513 200 TRUE 1.34
non-small cell lung cancer KRAS_G12D TP53 156 2050 Race:overall -0.92 -1.42 -0.42 1484.01 1.00 1781 110 2004 46 TRUE 3.54
pancreatic cancer KRAS_G12D TP53 494 944 Race:overall 0.94 0.62 1.25 1509.37 1.00 469 118 568 376 TRUE 8.61
uterine cancer KRAS_G12D TP53 51 541 Race:overall -1.11 -1.96 -0.26 1497.44 1.00 634 40 530 11 TRUE 1.96
colorectal cancer KRAS_G12D ATRX 215 96 White -0.02 -0.68 0.58 1093.39 1.00 1456 203 84 12 TRUE 0.02
non-small cell lung cancer KRAS_G12D ATRX 11 11 Black 0.17 -0.98 1.34 806.02 1.00 175 10 10 1 TRUE 0.11
non-small cell lung cancer KRAS_G12D ATRX 123 186 White 0.15 -0.57 0.81 270.87 1.00 2642 114 177 9 TRUE 0.17
uterine cancer KRAS_G12D ATRX 37 136 White -1.16 -2.66 -0.08 225.32 1.02 687 34 133 3 TRUE 1.09
colorectal cancer KRAS_G12D ATRX 215 96 Race:overall 0.00 -4.82 4.65 1439.65 1.00 1456 203 84 12 TRUE 0.00
non-small cell lung cancer KRAS_G12D ATRX 134 197 Race:overall 0.16 -0.88 1.14 755.81 1.00 2817 124 187 10 TRUE 0.12
uterine cancer KRAS_G12D ATRX 46 175 Race:overall -1.22 -2.76 -0.05 268.03 1.02 890 43 172 3 TRUE 1.07
colorectal cancer KRAS_G12D ATR 22 11 Asian -0.82 -4.41 0.47 1137.15 1.00 120 22 11 0 FALSE 0.29
colorectal cancer KRAS_G12D ATR 217 88 White -0.13 -0.80 0.52 982.10 1.00 1469 206 77 11 FALSE 0.16
non-small cell lung cancer KRAS_G12D ATR 123 103 White -0.19 -1.39 0.71 1324.53 1.00 2700 119 99 4 FALSE 0.14
uterine cancer KRAS_G12D ATR 38 81 White -0.91 -2.65 0.45 1341.76 1.00 715 36 79 2 FALSE 0.60
colorectal cancer KRAS_G12D ATR 239 99 Race:overall -0.44 -2.55 0.69 1424.67 1.00 1589 228 88 11 FALSE 0.22
non-small cell lung cancer KRAS_G12D ATR 123 103 Race:overall -0.09 -4.34 4.82 1500.51 1.00 2700 119 99 4 FALSE 0.01
uterine cancer KRAS_G12D ATR 38 81 Race:overall -0.76 -5.25 4.14 1470.22 1.00 715 36 79 2 FALSE 0.14
colorectal cancer KRAS_G12D PDGFRA 246 44 White 0.19 -0.71 0.99 1105.98 1.00 1649 239 37 7 TRUE 0.18
non-small cell lung cancer KRAS_G12D PDGFRA 8 13 Asian -0.84 -2.68 0.58 892.89 1.00 329 8 13 0 TRUE 0.50
non-small cell lung cancer KRAS_G12D PDGFRA 9 12 Unknown -0.64 -2.37 0.86 884.04 1.00 160 8 11 1 TRUE 0.38
non-small cell lung cancer KRAS_G12D PDGFRA 128 112 White -0.85 -2.40 0.29 1049.16 1.00 2777 126 110 2 TRUE 0.72
colorectal cancer KRAS_G12D PDGFRA 246 44 Race:overall 0.19 -4.08 4.86 1572.77 1.00 1649 239 37 7 TRUE 0.03
non-small cell lung cancer KRAS_G12D PDGFRA 145 137 Race:overall -0.79 -2.42 0.45 870.36 1.00 3266 142 134 3 TRUE 0.57
colorectal cancer KRAS_G12D FBXW7 30 34 Asian 0.31 -0.25 0.83 1457.72 1.00 129 23 27 7 TRUE 0.60
colorectal cancer KRAS_G12D FBXW7 30 20 Black 0.21 -0.48 0.73 1429.53 1.00 107 27 17 3 TRUE 0.31
colorectal cancer KRAS_G12D FBXW7 19 26 Unknown 0.27 -0.38 0.81 1512.42 1.00 89 15 22 4 TRUE 0.44
colorectal cancer KRAS_G12D FBXW7 256 254 White 0.32 0.00 0.65 1345.43 1.00 1498 212 210 44 TRUE 1.32
non-small cell lung cancer KRAS_G12D FBXW7 128 64 White -0.65 -2.50 0.66 146.30 1.02 2825 126 62 2 TRUE 0.36
uterine cancer KRAS_G12D FBXW7 40 115 White 0.90 0.12 1.48 58.99 1.04 745 30 105 10 TRUE 1.88
colorectal cancer KRAS_G12D FBXW7 335 334 Race:overall 0.28 -0.19 0.72 1484.24 1.00 1823 277 276 58 TRUE 0.66
non-small cell lung cancer KRAS_G12D FBXW7 128 64 Race:overall -0.55 -5.33 4.14 1302.07 1.00 2825 126 62 2 TRUE 0.10
uterine cancer KRAS_G12D FBXW7 43 130 Race:overall 0.87 -0.39 1.87 92.14 1.03 837 32 119 11 TRUE 0.88
colorectal cancer KRAS_G12D MAP3K1 215 70 White -0.50 -1.46 0.32 1500.10 1.00 1469 209 64 6 FALSE 0.58
non-small cell lung cancer KRAS_G12D MAP3K1 123 56 White -0.39 -2.18 0.90 1272.06 1.00 2742 121 54 2 FALSE 0.20
uterine cancer KRAS_G12D MAP3K1 38 57 White 0.35 -0.90 1.42 1250.50 1.00 715 34 53 4 FALSE 0.26
colorectal cancer KRAS_G12D MAP3K1 215 70 Race:overall -0.45 -4.49 3.87 1535.70 1.00 1469 209 64 6 FALSE 0.09
non-small cell lung cancer KRAS_G12D MAP3K1 123 56 Race:overall -0.37 -5.19 4.18 1343.35 1.00 2742 121 54 2 FALSE 0.06
uterine cancer KRAS_G12D MAP3K1 38 57 Race:overall 0.27 -4.23 4.65 1464.62 1.00 715 34 53 4 FALSE 0.05
colorectal cancer KRAS_G12D NSD1 215 71 White -1.39 -2.70 -0.28 204.16 1.02 1469 212 68 3 FALSE 1.43
non-small cell lung cancer KRAS_G12D NSD1 123 67 White -5.30 -14.88 -0.90 32.70 1.04 2728 123 67 0 FALSE 0.65
uterine cancer KRAS_G12D NSD1 39 95 White -0.14 -1.01 0.87 135.30 1.04 700 34 90 5 FALSE 0.11
colorectal cancer KRAS_G12D NSD1 215 71 Race:overall -1.07 -5.22 3.36 1342.82 1.00 1469 212 68 3 FALSE 0.22
non-small cell lung cancer KRAS_G12D NSD1 123 67 Race:overall -4.07 -11.50 2.37 643.94 1.01 2728 123 67 0 FALSE 0.70
uterine cancer KRAS_G12D NSD1 41 106 Race:overall -0.23 -1.94 1.20 1261.19 1.00 753 36 101 5 FALSE 0.11
colorectal cancer KRAS_G12D FLT4 217 115 White 0.04 -0.53 0.56 1239.11 1.00 1438 202 100 15 TRUE 0.05
non-small cell lung cancer KRAS_G12D FLT4 123 84 White -0.87 -2.66 0.43 1063.51 1.00 2715 121 82 2 TRUE 0.55
uterine cancer KRAS_G12D FLT4 37 34 White -0.93 -3.99 0.95 1023.87 1.00 732 36 33 1 TRUE 0.33
colorectal cancer KRAS_G12D FLT4 217 115 Race:overall 0.13 -3.96 4.73 1441.87 1.00 1438 202 100 15 TRUE 0.02
non-small cell lung cancer KRAS_G12D FLT4 123 84 Race:overall -0.64 -4.97 4.16 1378.64 1.00 2715 121 82 2 TRUE 0.11
uterine cancer KRAS_G12D FLT4 37 34 Race:overall -0.87 -5.66 3.82 1480.84 1.00 732 36 33 1 TRUE 0.15
cancer of unknown primary KRAS_G12D PTPRD 40 48 White -5.78 -14.93 -0.87 950.55 1.00 523 40 48 0 FALSE 0.74
colorectal cancer KRAS_G12D PTPRD 215 85 White -0.37 -1.17 0.32 1472.69 1.00 1464 207 77 8 FALSE 0.48
non-small cell lung cancer KRAS_G12D PTPRD 8 18 Asian -0.23 -1.58 0.77 1397.90 1.00 304 8 18 0 FALSE 0.16
non-small cell lung cancer KRAS_G12D PTPRD 11 27 Black -0.31 -1.62 0.69 1662.17 1.00 158 11 27 0 FALSE 0.21
non-small cell lung cancer KRAS_G12D PTPRD 9 21 Unknown 0.02 -1.05 1.09 1415.63 1.00 154 7 19 2 FALSE 0.01
non-small cell lung cancer KRAS_G12D PTPRD 123 320 White -0.02 -0.62 0.53 1478.80 1.00 2537 109 306 14 FALSE 0.02
uterine cancer KRAS_G12D PTPRD 37 82 White -1.87 -4.61 -0.07 1441.01 1.00 715 36 81 1 FALSE 0.94
cancer of unknown primary KRAS_G12D PTPRD 40 48 Race:overall -4.24 -11.29 2.67 898.25 1.00 523 40 48 0 FALSE 0.65
colorectal cancer KRAS_G12D PTPRD 215 85 Race:overall -0.34 -5.08 4.45 1585.20 1.00 1464 207 77 8 FALSE 0.06
non-small cell lung cancer KRAS_G12D PTPRD 151 386 Race:overall -0.14 -1.07 0.66 1581.05 1.00 3153 135 370 16 FALSE 0.12
uterine cancer KRAS_G12D PTPRD 37 82 Race:overall -1.56 -6.36 3.30 1484.58 1.00 715 36 81 1 FALSE 0.30
colorectal cancer KRAS_G12D RET 246 58 White -0.80 -1.94 0.18 1361.90 1.00 1633 242 54 4 TRUE 0.86
non-small cell lung cancer KRAS_G12D RET 128 81 White -0.91 -2.56 0.45 202.67 1.02 2804 126 79 2 TRUE 0.56
colorectal cancer KRAS_G12D RET 246 58 Race:overall -0.62 -4.71 3.80 1583.52 1.00 1633 242 54 4 TRUE 0.12
non-small cell lung cancer KRAS_G12D RET 128 81 Race:overall -0.78 -5.00 3.92 857.72 1.00 2804 126 79 2 TRUE 0.15
colorectal cancer KRAS_G12D KDM5A 217 74 White -0.22 -1.01 0.51 1574.92 1.00 1472 209 66 8 FALSE 0.24
non-small cell lung cancer KRAS_G12D KDM5A 123 62 White -1.46 -4.30 0.37 1425.37 1.00 2737 122 61 1 FALSE 0.67
uterine cancer KRAS_G12D KDM5A 37 49 White -0.34 -2.04 1.00 940.64 1.00 726 35 47 2 FALSE 0.17
colorectal cancer KRAS_G12D KDM5A 217 74 Race:overall -0.22 -4.42 4.34 1439.08 1.00 1472 209 66 8 FALSE 0.04
non-small cell lung cancer KRAS_G12D KDM5A 123 62 Race:overall -1.28 -5.87 3.29 1491.54 1.00 2737 122 61 1 FALSE 0.24
uterine cancer KRAS_G12D KDM5A 37 49 Race:overall -0.20 -4.63 4.07 1522.42 1.00 726 35 47 2 FALSE 0.03
colorectal cancer KRAS_G12D PIK3C2G 215 65 White -2.59 -5.24 -0.85 1482.42 1.00 1468 214 64 1 FALSE 1.60
non-small cell lung cancer KRAS_G12D PIK3C2G 123 113 White -0.06 -1.02 0.81 1541.64 1.00 2694 118 108 5 FALSE 0.04
colorectal cancer KRAS_G12D PIK3C2G 215 65 Race:overall -2.09 -6.62 2.77 1010.13 1.01 1468 214 64 1 FALSE 0.43
non-small cell lung cancer KRAS_G12D PIK3C2G 123 113 Race:overall -0.09 -4.35 4.07 1628.43 1.00 2694 118 108 5 FALSE 0.02
non-small cell lung cancer KRAS_G12D TSHR 124 58 White 0.06 -1.35 1.10 1042.16 1.00 2741 121 55 3 TRUE 0.03
non-small cell lung cancer KRAS_G12D TSHR 124 58 Race:overall 0.08 -4.13 4.69 1548.07 1.00 2741 121 55 3 TRUE 0.01
cancer of unknown primary KRAS_G12D CREBBP 40 49 White -0.80 -2.70 0.54 1077.35 1.00 520 38 47 2 TRUE 0.47
colorectal cancer KRAS_G12D CREBBP 23 13 Asian -0.32 -1.05 0.36 1559.46 1.00 121 21 11 2 TRUE 0.45
colorectal cancer KRAS_G12D CREBBP 27 11 Black -0.40 -1.15 0.23 1116.86 1.00 112 27 11 0 TRUE 0.61
colorectal cancer KRAS_G12D CREBBP 21 11 Unknown -0.23 -0.95 0.52 1491.75 1.00 103 17 7 4 TRUE 0.27
colorectal cancer KRAS_G12D CREBBP 219 148 White -0.39 -0.94 0.09 947.61 1.00 1419 207 136 12 TRUE 0.87
non-small cell lung cancer KRAS_G12D CREBBP 123 122 White -1.66 -3.16 0.01 3.30 1.39 2684 121 120 2 TRUE 1.04
uterine cancer KRAS_G12D CREBBP 37 78 White -0.89 -2.72 0.40 1134.93 1.00 704 35 76 2 TRUE 0.58
cancer of unknown primary KRAS_G12D CREBBP 40 49 Race:overall -0.64 -4.93 3.92 1342.39 1.00 520 38 47 2 TRUE 0.12
colorectal cancer KRAS_G12D CREBBP 290 183 Race:overall -0.34 -0.97 0.21 1558.40 1.00 1755 272 165 18 TRUE 0.59
non-small cell lung cancer KRAS_G12D CREBBP 123 122 Race:overall -1.54 -4.71 3.45 12.99 1.09 2684 121 120 2 TRUE 0.34
uterine cancer KRAS_G12D CREBBP 37 78 Race:overall -0.85 -5.39 3.72 1657.06 1.00 704 35 76 2 TRUE 0.16
non-small cell lung cancer KRAS_G12D BRIP1 123 53 White -1.29 -4.24 0.56 1279.91 1.00 2743 122 52 1 TRUE 0.54
non-small cell lung cancer KRAS_G12D BRIP1 123 53 Race:overall -1.11 -5.47 3.93 1474.51 1.00 2743 122 52 1 TRUE 0.21
colorectal cancer KRAS_G12D AXIN2 215 87 White -0.39 -1.17 0.31 1445.11 1.00 1459 207 79 8 TRUE 0.51
non-small cell lung cancer KRAS_G12D AXIN2 123 52 White -1.34 -4.64 0.56 392.51 1.00 2743 122 51 1 TRUE 0.54
uterine cancer KRAS_G12D AXIN2 37 46 White 0.23 -1.30 1.38 1264.75 1.00 723 34 43 3 TRUE 0.13
colorectal cancer KRAS_G12D AXIN2 215 87 Race:overall -0.36 -4.57 3.99 1601.41 1.00 1459 207 79 8 TRUE 0.07
non-small cell lung cancer KRAS_G12D AXIN2 123 52 Race:overall -1.09 -5.75 3.57 1243.85 1.00 2743 122 51 1 TRUE 0.19
uterine cancer KRAS_G12D AXIN2 37 46 Race:overall 0.24 -4.35 4.74 1233.96 1.00 723 34 43 3 TRUE 0.04
colorectal cancer KRAS_G12D DOT1L 216 67 White -0.25 -1.13 0.48 1116.43 1.00 1476 209 60 7 FALSE 0.26
non-small cell lung cancer KRAS_G12D DOT1L 123 88 White 0.24 -0.69 1.08 1374.36 1.00 2714 118 83 5 FALSE 0.22
colorectal cancer KRAS_G12D DOT1L 216 67 Race:overall -0.25 -4.76 4.15 1542.47 1.00 1476 209 60 7 FALSE 0.04
non-small cell lung cancer KRAS_G12D DOT1L 123 88 Race:overall 0.19 -4.19 4.43 1431.63 1.00 2714 118 83 5 FALSE 0.04
colorectal cancer KRAS_G12D PTPRS 22 21 Asian -0.07 -0.60 0.50 926.62 1.00 112 19 18 3 FALSE 0.10
colorectal cancer KRAS_G12D PTPRS 27 15 Black -0.10 -0.66 0.42 780.15 1.00 113 25 13 2 FALSE 0.14
colorectal cancer KRAS_G12D PTPRS 20 15 Unknown -0.02 -0.56 0.56 747.85 1.00 100 16 11 4 FALSE 0.03
colorectal cancer KRAS_G12D PTPRS 221 200 White -0.11 -0.53 0.28 762.46 1.00 1381 199 178 22 FALSE 0.22
non-small cell lung cancer KRAS_G12D PTPRS 123 69 White -1.80 -4.26 0.16 38.34 1.09 2732 122 68 1 FALSE 0.82
colorectal cancer KRAS_G12D PTPRS 290 251 Race:overall -0.07 -0.54 0.38 849.61 1.00 1706 259 220 31 FALSE 0.12
non-small cell lung cancer KRAS_G12D PTPRS 123 69 Race:overall -1.53 -5.59 3.34 239.36 1.03 2732 122 68 1 FALSE 0.30
cancer of unknown primary KRAS_G12D SMARCA4 40 50 White -0.70 -2.55 0.55 35.89 1.08 514 38 48 2 FALSE 0.37
colorectal cancer KRAS_G12D SMARCA4 27 19 Black -0.16 -1.19 0.59 1492.74 1.00 111 25 17 2 FALSE 0.14
colorectal cancer KRAS_G12D SMARCA4 19 14 Unknown -0.16 -1.26 0.63 1401.19 1.00 100 18 13 1 FALSE 0.13
colorectal cancer KRAS_G12D SMARCA4 218 126 White 0.04 -0.47 0.51 1252.72 1.00 1439 200 108 18 FALSE 0.06
non-small cell lung cancer KRAS_G12D SMARCA4 8 11 Asian 0.13 -1.14 1.35 1468.40 1.00 312 7 10 1 FALSE 0.08
non-small cell lung cancer KRAS_G12D SMARCA4 11 24 Black -0.03 -1.30 1.03 1508.08 1.00 163 10 23 1 FALSE 0.02
non-small cell lung cancer KRAS_G12D SMARCA4 9 11 Unknown -0.14 -1.61 1.08 1446.34 1.00 155 9 11 0 FALSE 0.08
non-small cell lung cancer KRAS_G12D SMARCA4 124 264 White 0.13 -0.46 0.67 1455.39 1.00 2559 111 251 13 FALSE 0.19
uterine cancer KRAS_G12D SMARCA4 37 80 White -0.91 -2.81 0.46 1486.90 1.00 706 35 78 2 FALSE 0.57
cancer of unknown primary KRAS_G12D SMARCA4 40 50 Race:overall -0.49 -4.79 3.85 712.16 1.01 514 38 48 2 FALSE 0.10
colorectal cancer KRAS_G12D SMARCA4 264 159 Race:overall -0.09 -0.91 0.60 1428.74 1.00 1650 243 138 21 FALSE 0.08
non-small cell lung cancer KRAS_G12D SMARCA4 152 310 Race:overall 0.02 -1.07 0.92 1467.56 1.00 3189 137 295 15 FALSE 0.02
uterine cancer KRAS_G12D SMARCA4 37 80 Race:overall -0.74 -5.09 3.89 1458.07 1.00 706 35 78 2 FALSE 0.14
cancer of unknown primary KRAS_G12D PTPRT 40 52 White -0.78 -2.58 0.55 1427.47 1.00 521 38 50 2 FALSE 0.49
colorectal cancer KRAS_G12D PTPRT 19 12 Unknown -0.80 -3.43 0.31 1070.34 1.00 101 19 12 0 FALSE 0.33
colorectal cancer KRAS_G12D PTPRT 216 150 White -0.29 -0.84 0.23 1256.78 1.00 1406 200 134 16 FALSE 0.56
non-small cell lung cancer KRAS_G12D PTPRT 8 12 Asian -0.68 -2.68 0.53 1112.01 1.00 310 8 12 0 FALSE 0.39
non-small cell lung cancer KRAS_G12D PTPRT 11 21 Black -0.77 -2.57 0.42 1291.67 1.00 165 11 21 0 FALSE 0.48
non-small cell lung cancer KRAS_G12D PTPRT 9 16 Unknown -0.74 -2.96 0.51 1295.71 1.00 152 9 16 0 FALSE 0.42
non-small cell lung cancer KRAS_G12D PTPRT 126 299 White -0.23 -0.87 0.32 1520.43 1.00 2559 114 287 12 FALSE 0.35
uterine cancer KRAS_G12D PTPRT 37 69 White -0.83 -2.50 0.58 123.31 1.04 711 35 67 2 FALSE 0.51
cancer of unknown primary KRAS_G12D PTPRT 40 52 Race:overall -0.63 -4.91 3.99 1178.89 1.00 521 38 50 2 FALSE 0.12
colorectal cancer KRAS_G12D PTPRT 235 162 Race:overall -0.54 -2.50 0.40 1612.69 1.00 1507 219 146 16 FALSE 0.33
non-small cell lung cancer KRAS_G12D PTPRT 154 348 Race:overall -0.62 -2.17 0.38 1185.28 1.00 3186 142 336 12 FALSE 0.46
uterine cancer KRAS_G12D PTPRT 37 69 Race:overall -0.67 -4.76 3.88 1259.84 1.01 711 35 67 2 FALSE 0.13
colorectal cancer KRAS_G12D HGF 215 39 White -0.66 -2.07 0.42 1374.64 1.00 1493 212 36 3 FALSE 0.54
non-small cell lung cancer KRAS_G12D HGF 11 17 Black -0.29 -1.86 0.94 1400.58 1.00 168 10 16 1 FALSE 0.17
non-small cell lung cancer KRAS_G12D HGF 123 156 White -0.34 -1.25 0.46 1313.55 1.00 2655 118 151 5 FALSE 0.37
colorectal cancer KRAS_G12D HGF 215 39 Race:overall -0.60 -4.71 3.36 1390.27 1.00 1493 212 36 3 FALSE 0.12
non-small cell lung cancer KRAS_G12D HGF 134 173 Race:overall -0.30 -1.66 1.03 1542.82 1.00 2823 128 167 6 FALSE 0.18
colorectal cancer KRAS_G12D BLM 215 50 White -6.92 -16.79 -1.66 772.96 1.00 1484 215 50 0 TRUE 0.43
colorectal cancer KRAS_G12D BLM 215 50 Race:overall -4.77 -12.61 2.96 1084.28 1.00 1484 215 50 0 TRUE 0.70
cancer of unknown primary KRAS_G12D PIK3CA 40 80 White -0.11 -1.27 0.81 1108.42 1.00 504 35 75 5 TRUE 0.08
colorectal cancer KRAS_G12D PIK3CA 27 33 Asian -0.03 -0.89 0.56 1197.78 1.00 128 23 29 4 TRUE 0.03
colorectal cancer KRAS_G12D PIK3CA 30 32 Black -0.08 -1.02 0.56 1049.39 1.00 97 26 28 4 TRUE 0.07
colorectal cancer KRAS_G12D PIK3CA 19 30 Unknown -0.21 -1.40 0.52 1119.61 1.00 85 18 29 1 TRUE 0.17
colorectal cancer KRAS_G12D PIK3CA 252 403 White 0.39 0.09 0.71 960.53 1.00 1392 179 330 73 TRUE 1.88
non-small cell lung cancer KRAS_G12D PIK3CA 8 31 Asian 0.19 -0.77 1.12 635.31 1.00 311 7 30 1 TRUE 0.16
non-small cell lung cancer KRAS_G12D PIK3CA 11 13 Black 0.20 -0.81 1.20 630.39 1.01 177 10 12 1 TRUE 0.16
non-small cell lung cancer KRAS_G12D PIK3CA 128 189 White 0.19 -0.42 0.79 279.84 1.01 2710 118 179 10 TRUE 0.26
uterine cancer KRAS_G12D PIK3CA 44 430 White 1.04 0.46 1.61 684.37 1.00 534 14 400 30 TRUE 3.39
cancer of unknown primary KRAS_G12D PIK3CA 40 80 Race:overall -0.12 -4.16 4.31 1270.08 1.00 504 35 75 5 TRUE 0.02
colorectal cancer KRAS_G12D PIK3CA 328 498 Race:overall 0.02 -0.71 0.55 1313.00 1.00 1702 246 416 82 TRUE 0.02
non-small cell lung cancer KRAS_G12D PIK3CA 147 233 Race:overall 0.20 -0.60 1.03 493.37 1.01 3198 135 221 12 TRUE 0.20
uterine cancer KRAS_G12D PIK3CA 58 557 Race:overall 1.04 0.41 1.65 688.69 1.00 720 19 518 39 TRUE 3.03
non-small cell lung cancer KRAS_G12D GATA3 123 57 White -1.43 -4.11 0.40 653.88 1.00 2742 122 56 1 FALSE 0.64
non-small cell lung cancer KRAS_G12D GATA3 123 57 Race:overall -1.14 -5.54 4.01 1313.23 1.00 2742 122 56 1 FALSE 0.20
colorectal cancer KRAS_G12D ESR1 215 61 White -0.31 -1.32 0.48 1041.28 1.00 1473 209 55 6 TRUE 0.30
non-small cell lung cancer KRAS_G12D ESR1 123 45 White -0.18 -2.00 1.19 944.70 1.00 2754 121 43 2 TRUE 0.09
colorectal cancer KRAS_G12D ESR1 215 61 Race:overall -0.29 -4.85 4.12 1356.32 1.00 1473 209 55 6 TRUE 0.05
non-small cell lung cancer KRAS_G12D ESR1 123 45 Race:overall -0.20 -4.52 4.31 1334.42 1.00 2754 121 43 2 TRUE 0.03
colorectal cancer KRAS_G12D ALK 246 95 White -0.51 -1.30 0.18 1066.93 1.00 1613 238 87 8 TRUE 0.75
non-small cell lung cancer KRAS_G12D ALK 8 13 Asian -0.66 -3.53 0.91 1362.20 1.00 329 8 13 0 TRUE 0.24
non-small cell lung cancer KRAS_G12D ALK 128 141 White -0.35 -1.41 0.53 1159.06 1.00 2753 123 136 5 TRUE 0.32
uterine cancer KRAS_G12D ALK 38 45 White -1.18 -3.94 0.67 1306.63 1.00 804 37 44 1 TRUE 0.48
colorectal cancer KRAS_G12D ALK 246 95 Race:overall -0.34 -4.54 4.15 1391.01 1.00 1613 238 87 8 TRUE 0.06
non-small cell lung cancer KRAS_G12D ALK 136 154 Race:overall -0.48 -2.46 1.03 1462.37 1.00 3082 131 149 5 TRUE 0.23
uterine cancer KRAS_G12D ALK 38 45 Race:overall -0.85 -5.30 4.21 1443.68 1.00 804 37 44 1 TRUE 0.15
colorectal cancer KRAS_G12D RNF43 23 21 Asian -0.01 -0.70 0.81 594.27 1.00 117 19 17 4 TRUE 0.01
colorectal cancer KRAS_G12D RNF43 29 15 Black 0.06 -0.64 1.01 557.45 1.00 113 24 10 5 TRUE 0.06
colorectal cancer KRAS_G12D RNF43 220 217 White -0.27 -0.74 0.16 1026.41 1.00 1378 201 198 19 TRUE 0.60
pancreatic cancer KRAS_G12D RNF43 407 66 White 0.29 -0.13 0.85 25.68 1.09 786 380 39 27 TRUE 0.53
uterine cancer KRAS_G12D RNF43 40 77 White 0.48 -0.42 1.35 1475.21 1.00 698 34 71 6 TRUE 0.51
colorectal cancer KRAS_G12D RNF43 272 253 Race:overall -0.06 -0.70 0.66 683.83 1.00 1608 244 225 28 TRUE 0.07
pancreatic cancer KRAS_G12D RNF43 407 66 Race:overall 0.24 -3.98 4.19 1408.19 1.01 786 380 39 27 TRUE 0.05
uterine cancer KRAS_G12D RNF43 40 77 Race:overall 0.30 -4.24 4.32 1370.67 1.00 698 34 71 6 TRUE 0.05
non-small cell lung cancer KRAS_G12D U2AF1 124 65 White 0.77 -0.23 1.59 796.14 1.00 2736 118 59 6 FALSE 1.01
non-small cell lung cancer KRAS_G12D U2AF1 124 65 Race:overall 0.50 -4.18 4.69 1488.94 1.00 2736 118 59 6 FALSE 0.09
colorectal cancer KRAS_G12D LATS1 215 40 White -1.17 -2.81 0.02 1347.77 1.00 1492 213 38 2 FALSE 0.95
non-small cell lung cancer KRAS_G12D LATS1 123 59 White -0.48 -2.23 0.78 1491.66 1.00 2738 121 57 2 FALSE 0.27
colorectal cancer KRAS_G12D LATS1 215 40 Race:overall -0.96 -5.30 3.83 1434.13 1.00 1492 213 38 2 FALSE 0.18
non-small cell lung cancer KRAS_G12D LATS1 123 59 Race:overall -0.36 -4.31 4.53 1598.23 1.00 2738 121 57 2 FALSE 0.07
colorectal cancer KRAS_G12D LATS2 215 58 White -0.27 -1.20 0.52 1403.30 1.00 1476 209 52 6 FALSE 0.25
non-small cell lung cancer KRAS_G12D LATS2 123 45 White -1.23 -3.84 0.63 281.48 1.02 2750 122 44 1 FALSE 0.55
colorectal cancer KRAS_G12D LATS2 215 58 Race:overall -0.26 -4.58 4.11 1616.80 1.00 1476 209 52 6 FALSE 0.05
non-small cell lung cancer KRAS_G12D LATS2 123 45 Race:overall -0.91 -4.86 4.34 1137.37 1.01 2750 122 44 1 FALSE 0.16
colorectal cancer KRAS_G12D PTEN 27 11 Asian -0.58 -1.52 0.15 1373.64 1.00 144 26 10 1 TRUE 0.77
colorectal cancer KRAS_G12D PTEN 30 12 Black -0.66 -1.79 0.08 1102.33 1.00 112 30 12 0 TRUE 0.79
colorectal cancer KRAS_G12D PTEN 19 17 Unknown -0.58 -1.55 0.17 1308.31 1.00 98 18 16 1 TRUE 0.73
colorectal cancer KRAS_G12D PTEN 248 141 White -0.41 -0.95 0.10 952.52 1.00 1593 233 126 15 TRUE 0.91
non-small cell lung cancer KRAS_G12D PTEN 8 13 Asian -0.92 -3.36 0.82 1206.30 1.00 329 8 13 0 TRUE 0.41
non-small cell lung cancer KRAS_G12D PTEN 128 111 White -0.76 -2.23 0.35 501.41 1.01 2778 125 108 3 TRUE 0.66
uterine cancer KRAS_G12D PTEN 6 43 Asian 1.17 0.18 2.23 1170.67 1.00 60 2 39 4 TRUE 1.60
uterine cancer KRAS_G12D PTEN 6 28 Black 1.54 0.48 2.78 1588.41 1.00 90 1 23 5 TRUE 2.08
uterine cancer KRAS_G12D PTEN 54 504 White 0.99 0.44 1.56 1392.27 1.00 539 17 467 37 TRUE 3.36
colorectal cancer KRAS_G12D PTEN 324 181 Race:overall -0.56 -1.35 0.07 1142.15 1.00 1947 307 164 17 TRUE 0.92
non-small cell lung cancer KRAS_G12D PTEN 136 124 Race:overall -0.85 -2.85 0.75 1205.47 1.00 3107 133 121 3 TRUE 0.48
uterine cancer KRAS_G12D PTEN 73 627 Race:overall 1.18 0.34 2.08 1357.19 1.00 748 23 577 50 TRUE 2.09
colorectal cancer KRAS_G12D BCOR 215 94 White -0.38 -1.04 0.30 44.04 1.07 1457 206 85 9 FALSE 0.49
non-small cell lung cancer KRAS_G12D BCOR 123 117 White -0.07 -1.06 0.77 1468.20 1.00 2692 118 112 5 FALSE 0.06
uterine cancer KRAS_G12D BCOR 37 124 White 0.44 -0.41 1.21 1023.40 1.00 668 29 116 8 FALSE 0.53
colorectal cancer KRAS_G12D BCOR 215 94 Race:overall -0.33 -3.96 3.94 1555.80 1.00 1457 206 85 9 FALSE 0.07
non-small cell lung cancer KRAS_G12D BCOR 123 117 Race:overall -0.04 -4.80 4.55 1215.45 1.00 2692 118 112 5 FALSE 0.01
uterine cancer KRAS_G12D BCOR 37 124 Race:overall 0.38 -3.80 4.59 1252.92 1.00 668 29 116 8 FALSE 0.07
colorectal cancer KRAS_G12D CTNNB1 27 15 Asian 0.01 -1.39 0.77 149.09 1.03 138 26 14 1 TRUE 0.01
colorectal cancer KRAS_G12D CTNNB1 30 13 Black -0.02 -1.57 0.75 151.33 1.03 111 29 12 1 TRUE 0.01
colorectal cancer KRAS_G12D CTNNB1 249 124 White 0.47 -0.03 0.91 650.07 1.01 1591 223 98 26 TRUE 1.33
non-small cell lung cancer KRAS_G12D CTNNB1 8 17 Asian -0.43 -2.09 0.86 1373.93 1.00 324 8 17 0 TRUE 0.24
non-small cell lung cancer KRAS_G12D CTNNB1 11 11 Black -0.22 -1.80 1.25 1356.40 1.00 178 10 10 1 TRUE 0.12
non-small cell lung cancer KRAS_G12D CTNNB1 129 88 White -0.34 -1.60 0.65 1252.01 1.00 2797 126 85 3 TRUE 0.26
uterine cancer KRAS_G12D CTNNB1 38 112 White -0.85 -2.46 0.28 784.47 1.00 734 35 109 3 TRUE 0.68
colorectal cancer KRAS_G12D CTNNB1 306 152 Race:overall 0.15 -0.96 0.79 194.17 1.03 1840 278 124 28 TRUE 0.13
non-small cell lung cancer KRAS_G12D CTNNB1 148 116 Race:overall -0.32 -1.69 0.89 1280.99 1.00 3299 144 112 4 TRUE 0.21
uterine cancer KRAS_G12D CTNNB1 42 127 Race:overall -0.98 -2.94 0.53 1167.77 1.00 802 39 124 3 TRUE 0.56
cancer of unknown primary KRAS_G12D ARID1A 41 105 White -0.47 -1.51 0.44 1317.46 1.00 485 36 100 5 TRUE 0.46
colorectal cancer KRAS_G12D ARID1A 22 22 Asian -0.27 -0.83 0.31 1333.64 1.00 115 18 18 4 TRUE 0.46
colorectal cancer KRAS_G12D ARID1A 27 24 Black -0.44 -1.44 0.12 1302.78 1.00 107 27 24 0 TRUE 0.59
colorectal cancer KRAS_G12D ARID1A 19 15 Unknown -0.42 -1.35 0.12 868.38 1.00 96 19 15 0 TRUE 0.59
colorectal cancer KRAS_G12D ARID1A 225 249 White -0.24 -0.63 0.16 1336.35 1.00 1373 196 220 29 TRUE 0.62
non-small cell lung cancer KRAS_G12D ARID1A 8 20 Asian -0.78 -2.30 0.36 1490.27 1.00 305 8 20 0 TRUE 0.62
non-small cell lung cancer KRAS_G12D ARID1A 11 20 Black -0.84 -2.53 0.23 1123.59 1.01 163 11 20 0 TRUE 0.65
non-small cell lung cancer KRAS_G12D ARID1A 123 231 White -0.57 -1.37 0.18 880.86 1.00 2591 116 224 7 TRUE 0.78
pancreatic cancer KRAS_G12D ARID1A 20 16 Asian 0.46 -0.53 1.39 1557.52 1.00 48 15 11 5 TRUE 0.46
pancreatic cancer KRAS_G12D ARID1A 409 104 White 0.49 0.09 0.88 1544.56 1.00 769 363 58 46 TRUE 1.82
uterine cancer KRAS_G12D ARID1A 43 427 White 0.62 0.06 1.21 1333.28 1.00 498 17 401 26 TRUE 1.40
cancer of unknown primary KRAS_G12D ARID1A 41 105 Race:overall -0.42 -4.41 4.02 1362.64 1.00 485 36 100 5 TRUE 0.08
colorectal cancer KRAS_G12D ARID1A 293 310 Race:overall -0.34 -0.92 0.11 1308.01 1.00 1691 260 277 33 TRUE 0.68
non-small cell lung cancer KRAS_G12D ARID1A 142 271 Race:overall -0.74 -1.97 0.23 1166.31 1.00 3059 135 264 7 TRUE 0.74
pancreatic cancer KRAS_G12D ARID1A 429 120 Race:overall 0.46 -0.93 1.78 1646.15 1.00 817 378 69 51 TRUE 0.29
uterine cancer KRAS_G12D ARID1A 54 517 Race:overall 0.51 -0.44 1.44 1337.65 1.00 665 23 486 31 TRUE 0.55
colorectal cancer KRAS_G12D PIK3R1 218 95 White 0.26 -0.35 0.84 1340.34 1.00 1459 203 80 15 TRUE 0.42
non-small cell lung cancer KRAS_G12D PIK3R1 123 41 White 0.42 -0.97 1.54 1488.37 1.00 2756 120 38 3 TRUE 0.29
uterine cancer KRAS_G12D PIK3R1 39 215 White -0.56 -1.43 0.20 1262.91 1.00 595 32 208 7 TRUE 0.76
colorectal cancer KRAS_G12D PIK3R1 218 95 Race:overall 0.17 -4.35 4.57 1388.10 1.00 1459 203 80 15 TRUE 0.03
non-small cell lung cancer KRAS_G12D PIK3R1 123 41 Race:overall 0.39 -4.24 4.97 1293.90 1.00 2756 120 38 3 TRUE 0.07
uterine cancer KRAS_G12D PIK3R1 45 254 Race:overall -0.57 -1.56 0.35 1381.96 1.00 691 37 246 8 TRUE 0.63
colorectal cancer KRAS_G12D IKZF1 215 69 White -0.51 -1.44 0.29 514.62 1.01 1467 209 63 6 TRUE 0.59
non-small cell lung cancer KRAS_G12D IKZF1 123 67 White -0.07 -1.46 1.06 1002.23 1.00 2731 120 64 3 TRUE 0.04
colorectal cancer KRAS_G12D IKZF1 215 69 Race:overall -0.49 -5.17 3.67 1422.37 1.00 1467 209 63 6 TRUE 0.09
non-small cell lung cancer KRAS_G12D IKZF1 123 67 Race:overall -0.04 -4.50 4.82 1459.55 1.00 2731 120 64 3 TRUE 0.01
cancer of unknown primary KRAS_G12D TERT 40 77 White -6.33 -16.07 -1.44 1501.15 1.00 495 40 77 0 TRUE 0.89
colorectal cancer KRAS_G12D TERT 219 75 White 0.48 -0.11 1.07 1091.48 1.00 1469 205 61 14 TRUE 0.97
non-small cell lung cancer KRAS_G12D TERT 8 11 Asian -0.62 -3.36 1.07 1118.11 1.00 312 8 11 0 TRUE 0.24
non-small cell lung cancer KRAS_G12D TERT 123 135 White -0.27 -1.38 0.56 629.29 1.00 2670 118 130 5 TRUE 0.24
uterine cancer KRAS_G12D TERT 37 47 White -1.32 -4.14 0.53 1376.44 1.00 715 36 46 1 TRUE 0.58
cancer of unknown primary KRAS_G12D TERT 40 77 Race:overall -4.63 -12.59 2.77 1139.66 1.00 495 40 77 0 TRUE 0.71
colorectal cancer KRAS_G12D TERT 219 75 Race:overall 0.46 -4.00 4.86 1588.28 1.00 1469 205 61 14 TRUE 0.08
non-small cell lung cancer KRAS_G12D TERT 131 146 Race:overall -0.45 -2.38 1.06 938.23 1.00 2982 126 141 5 TRUE 0.22
uterine cancer KRAS_G12D TERT 37 47 Race:overall -1.06 -5.18 3.97 1414.48 1.00 715 36 46 1 TRUE 0.20
cancer of unknown primary KRAS_G12D FAT1 41 58 White -0.95 -2.62 0.40 1269.31 1.00 514 39 56 2 FALSE 0.65
colorectal cancer KRAS_G12D FAT1 22 15 Asian -0.68 -1.68 0.00 1091.83 1.00 120 22 15 0 FALSE 1.01
colorectal cancer KRAS_G12D FAT1 27 11 Black -0.67 -1.63 -0.03 1135.90 1.00 117 27 11 0 FALSE 1.05
colorectal cancer KRAS_G12D FAT1 19 19 Unknown -0.59 -1.33 0.08 1258.74 1.00 103 17 17 2 FALSE 1.02
colorectal cancer KRAS_G12D FAT1 220 180 White -0.52 -1.03 -0.04 1162.78 1.00 1408 203 163 17 FALSE 1.43
non-small cell lung cancer KRAS_G12D FAT1 8 13 Asian -0.46 -2.00 0.69 1341.19 1.00 308 8 13 0 FALSE 0.30
non-small cell lung cancer KRAS_G12D FAT1 11 12 Black -0.46 -1.97 0.65 1195.66 1.00 173 11 12 0 FALSE 0.31
non-small cell lung cancer KRAS_G12D FAT1 9 15 Unknown -0.48 -2.01 0.56 1283.14 1.00 151 9 15 0 FALSE 0.33
non-small cell lung cancer KRAS_G12D FAT1 124 261 White -0.16 -0.84 0.46 1361.20 1.00 2572 113 250 11 FALSE 0.20
uterine cancer KRAS_G12D FAT1 39 150 White -0.42 -1.31 0.36 786.67 1.00 678 33 144 6 FALSE 0.48
cancer of unknown primary KRAS_G12D FAT1 41 58 Race:overall -0.76 -4.80 4.20 1346.28 1.00 514 39 56 2 FALSE 0.15
colorectal cancer KRAS_G12D FAT1 288 225 Race:overall -0.61 -1.30 -0.04 1064.62 1.00 1748 269 206 19 FALSE 1.27
non-small cell lung cancer KRAS_G12D FAT1 152 301 Race:overall -0.39 -1.57 0.52 1254.67 1.00 3204 141 290 11 FALSE 0.34
uterine cancer KRAS_G12D FAT1 45 176 Race:overall -0.49 -1.65 0.40 801.32 1.01 792 39 170 6 FALSE 0.46
colorectal cancer KRAS_G12D FGFR4 217 39 White 0.55 -0.32 1.34 707.87 1.00 1496 209 31 8 TRUE 0.71
colorectal cancer KRAS_G12D FGFR4 217 39 Race:overall 0.46 -4.26 4.80 1192.46 1.00 1496 209 31 8 TRUE 0.08
colorectal cancer KRAS_G12D CIC 218 111 White 0.09 -0.46 0.60 1174.63 1.00 1448 203 96 15 TRUE 0.13
non-small cell lung cancer KRAS_G12D CIC 123 81 White 0.33 -0.74 1.19 1404.66 1.00 2730 118 76 5 TRUE 0.30
uterine cancer KRAS_G12D CIC 37 55 White 0.05 -1.44 1.21 1359.13 1.00 719 34 52 3 TRUE 0.03
colorectal cancer KRAS_G12D CIC 218 111 Race:overall -0.02 -4.50 4.17 1317.55 1.00 1448 203 96 15 TRUE 0.00
non-small cell lung cancer KRAS_G12D CIC 123 81 Race:overall 0.29 -4.04 4.86 1395.03 1.00 2730 118 76 5 TRUE 0.05
uterine cancer KRAS_G12D CIC 37 55 Race:overall -0.02 -4.52 4.17 1506.69 1.00 719 34 52 3 TRUE 0.00
colorectal cancer KRAS_G12D KDM6A 216 49 White 0.56 -0.18 1.23 1322.72 1.00 1490 206 39 10 FALSE 0.90
non-small cell lung cancer KRAS_G12D KDM6A 123 45 White -0.17 -1.98 1.16 1292.94 1.00 2753 121 43 2 FALSE 0.08
pancreatic cancer KRAS_G12D KDM6A 406 56 White 0.27 -0.32 0.79 1205.32 1.00 790 384 34 22 FALSE 0.46
uterine cancer KRAS_G12D KDM6A 37 41 White -0.15 -1.87 1.14 1281.93 1.00 727 35 39 2 FALSE 0.07
colorectal cancer KRAS_G12D KDM6A 216 49 Race:overall 0.46 -4.17 4.60 1599.83 1.00 1490 206 39 10 FALSE 0.08
non-small cell lung cancer KRAS_G12D KDM6A 123 45 Race:overall -0.10 -4.82 5.09 1400.86 1.00 2753 121 43 2 FALSE 0.02
pancreatic cancer KRAS_G12D KDM6A 406 56 Race:overall 0.17 -4.14 4.03 1523.12 1.00 790 384 34 22 FALSE 0.03
uterine cancer KRAS_G12D KDM6A 37 41 Race:overall -0.13 -4.63 4.57 1633.41 1.00 727 35 39 2 FALSE 0.02
colorectal cancer KRAS_G12D NCOR1 22 12 Asian -0.57 -1.76 0.41 978.45 1.00 119 21 11 1 FALSE 0.57
colorectal cancer KRAS_G12D NCOR1 216 108 White -0.53 -1.20 0.08 1250.59 1.00 1450 207 99 9 FALSE 1.00
non-small cell lung cancer KRAS_G12D NCOR1 123 82 White -1.68 -4.47 0.10 1219.95 1.00 2721 122 81 1 FALSE 0.80
uterine cancer KRAS_G12D NCOR1 38 76 White 0.06 -1.12 1.05 1270.32 1.00 718 34 72 4 FALSE 0.04
colorectal cancer KRAS_G12D NCOR1 238 120 Race:overall -0.55 -1.58 0.38 1422.24 1.00 1569 228 110 10 FALSE 0.58
non-small cell lung cancer KRAS_G12D NCOR1 123 82 Race:overall -1.34 -5.96 3.75 1307.34 1.00 2721 122 81 1 FALSE 0.25
uterine cancer KRAS_G12D NCOR1 38 76 Race:overall 0.08 -4.14 4.47 1489.14 1.00 718 34 72 4 FALSE 0.01
colorectal cancer KRAS_G12D POLE 22 13 Asian -0.39 -1.36 0.70 1339.39 1.00 122 20 11 2 TRUE 0.35
colorectal cancer KRAS_G12D POLE 215 115 White -0.50 -1.17 0.12 1431.18 1.00 1440 206 106 9 TRUE 0.88
non-small cell lung cancer KRAS_G12D POLE 123 112 White -0.65 -1.98 0.43 1516.24 1.00 2692 120 109 3 TRUE 0.53
uterine cancer KRAS_G12D POLE 38 91 White 0.31 -0.82 1.18 194.02 1.01 711 32 85 6 TRUE 0.28
colorectal cancer KRAS_G12D POLE 237 128 Race:overall -0.45 -1.39 0.53 1446.70 1.00 1562 226 117 11 TRUE 0.43
non-small cell lung cancer KRAS_G12D POLE 123 112 Race:overall -0.58 -5.19 3.83 1435.57 1.00 2692 120 109 3 TRUE 0.11
uterine cancer KRAS_G12D POLE 38 91 Race:overall 0.28 -3.78 4.48 1269.73 1.00 711 32 85 6 TRUE 0.05
non-small cell lung cancer KRAS_G12D CUL3 123 64 White -1.52 -4.02 0.24 670.64 1.00 2738 122 63 1 FALSE 0.76
non-small cell lung cancer KRAS_G12D CUL3 123 64 Race:overall -1.18 -5.27 3.74 1299.29 1.01 2738 122 63 1 FALSE 0.24
colorectal cancer KRAS_G12D ABL1 246 59 White -0.83 -1.93 0.10 790.31 1.00 1639 242 55 4 TRUE 0.92
colorectal cancer KRAS_G12D ABL1 246 59 Race:overall -0.72 -4.91 3.60 1328.93 1.00 1639 242 55 4 TRUE 0.15
colorectal cancer KRAS_G12D FOXP1 215 56 White -0.56 -1.39 0.33 24.63 1.05 1480 210 51 5 FALSE 0.74
colorectal cancer KRAS_G12D FOXP1 215 56 Race:overall -0.63 -4.13 3.01 1301.17 1.01 1480 210 51 5 FALSE 0.16
colorectal cancer KRAS_G12D NOTCH2 215 64 White -0.61 -1.64 0.26 1563.11 1.00 1476 210 59 5 TRUE 0.68
non-small cell lung cancer KRAS_G12D NOTCH2 123 98 White 0.12 -0.85 0.97 1433.53 1.00 2711 118 93 5 TRUE 0.10
colorectal cancer KRAS_G12D NOTCH2 215 64 Race:overall -0.55 -4.94 3.51 1472.59 1.00 1476 210 59 5 TRUE 0.11
non-small cell lung cancer KRAS_G12D NOTCH2 123 98 Race:overall 0.04 -4.62 4.85 1536.07 1.00 2711 118 93 5 TRUE 0.01
non-small cell lung cancer KRAS_G12D DDR2 123 82 White -1.76 -4.33 -0.02 1177.86 1.00 2713 122 81 1 TRUE 0.92
uterine cancer KRAS_G12D DDR2 37 47 White 0.23 -1.23 1.46 1177.19 1.00 730 34 44 3 TRUE 0.13
non-small cell lung cancer KRAS_G12D DDR2 123 82 Race:overall -1.44 -6.05 3.24 1360.87 1.00 2713 122 81 1 TRUE 0.28
uterine cancer KRAS_G12D DDR2 37 47 Race:overall 0.16 -4.22 4.23 1438.67 1.00 730 34 44 3 TRUE 0.03
colorectal cancer KRAS_G12D TGFBR2 216 93 White 0.37 -0.18 0.78 11.94 1.10 1453 201 78 15 TRUE 0.92
non-small cell lung cancer KRAS_G12D TGFBR2 123 48 White 0.28 -1.12 1.35 957.17 1.00 2753 120 45 3 TRUE 0.19
colorectal cancer KRAS_G12D TGFBR2 216 93 Race:overall 0.44 -3.63 3.93 1158.91 1.01 1453 201 78 15 TRUE 0.10
non-small cell lung cancer KRAS_G12D TGFBR2 123 48 Race:overall 0.14 -4.92 4.40 1614.16 1.00 2753 120 45 3 TRUE 0.02
colorectal cancer KRAS_G12D SMO 247 57 White 0.05 -0.73 0.79 1365.18 1.00 1641 239 49 8 TRUE 0.05
non-small cell lung cancer KRAS_G12D SMO 128 64 White 0.57 -0.46 1.45 1545.38 1.00 2824 123 59 5 TRUE 0.62
uterine cancer KRAS_G12D SMO 38 41 White 0.40 -0.96 1.60 827.59 1.00 808 35 38 3 TRUE 0.27
colorectal cancer KRAS_G12D SMO 247 57 Race:overall 0.01 -4.08 4.81 1314.03 1.00 1641 239 49 8 TRUE 0.00
non-small cell lung cancer KRAS_G12D SMO 128 64 Race:overall 0.46 -4.12 4.67 1438.72 1.00 2824 123 59 5 TRUE 0.08
uterine cancer KRAS_G12D SMO 38 41 Race:overall 0.28 -4.35 4.46 1428.06 1.00 808 35 38 3 TRUE 0.05
colorectal cancer KRAS_G12D RPS6KA4 215 46 White -0.23 -1.27 0.67 1528.12 1.00 1487 210 41 5 FALSE 0.19
colorectal cancer KRAS_G12D RPS6KA4 215 46 Race:overall -0.18 -4.47 3.98 1401.78 1.00 1487 210 41 5 FALSE 0.03
colorectal cancer KRAS_G12D KMT2A 216 122 White 0.22 -0.32 0.72 875.08 1.00 1443 198 104 18 FALSE 0.39
non-small cell lung cancer KRAS_G12D KMT2A 123 99 White -1.02 -2.85 0.27 1348.30 1.00 2703 121 97 2 FALSE 0.71
uterine cancer KRAS_G12D KMT2A 38 88 White -1.01 -2.81 0.26 1093.99 1.00 709 36 86 2 FALSE 0.70
colorectal cancer KRAS_G12D KMT2A 216 122 Race:overall 0.20 -4.07 4.50 1422.12 1.00 1443 198 104 18 FALSE 0.04
non-small cell lung cancer KRAS_G12D KMT2A 123 99 Race:overall -0.87 -5.03 3.84 1426.73 1.00 2703 121 97 2 FALSE 0.17
uterine cancer KRAS_G12D KMT2A 38 88 Race:overall -0.88 -4.81 3.71 1338.81 1.00 709 36 86 2 FALSE 0.18
colorectal cancer KRAS_G12D JAK3 246 51 White -1.54 -3.32 -0.24 1152.94 1.00 1641 244 49 2 TRUE 1.26
non-small cell lung cancer KRAS_G12D JAK3 128 73 White 0.64 -0.31 1.48 1532.97 1.00 2816 122 67 6 TRUE 0.82
colorectal cancer KRAS_G12D JAK3 246 51 Race:overall -1.30 -5.51 3.60 1381.56 1.00 1641 244 49 2 TRUE 0.27
non-small cell lung cancer KRAS_G12D JAK3 128 73 Race:overall 0.55 -3.83 5.28 1493.11 1.00 2816 122 67 6 TRUE 0.10
non-small cell lung cancer KRAS_G12D PAK7 9 14 Unknown -0.75 -3.96 0.97 1197.71 1.00 154 9 14 0 FALSE 0.25
non-small cell lung cancer KRAS_G12D PAK7 123 107 White -0.08 -1.08 0.80 940.10 1.00 2699 118 102 5 FALSE 0.06
non-small cell lung cancer KRAS_G12D PAK7 132 121 Race:overall -0.39 -2.83 1.23 1426.67 1.00 2853 127 116 5 FALSE 0.16
non-small cell lung cancer KRAS_G12D STAG2 123 85 White 0.02 -1.07 0.97 1263.21 1.00 2718 119 81 4 TRUE 0.02
uterine cancer KRAS_G12D STAG2 40 70 White 0.62 -0.38 1.49 1553.24 1.00 720 34 64 6 TRUE 0.70
non-small cell lung cancer KRAS_G12D STAG2 123 85 Race:overall -0.04 -4.45 4.27 1333.03 1.00 2718 119 81 4 TRUE 0.01
uterine cancer KRAS_G12D STAG2 40 70 Race:overall 0.62 -3.62 4.95 1147.40 1.00 720 34 64 6 TRUE 0.12
colorectal cancer KRAS_G12D BRCA2 22 18 Asian -0.92 -2.05 -0.10 1425.80 1.00 122 22 18 0 TRUE 1.11
colorectal cancer KRAS_G12D BRCA2 27 13 Black -0.75 -1.68 0.07 1334.10 1.00 113 25 11 2 TRUE 1.09
colorectal cancer KRAS_G12D BRCA2 216 149 White -0.78 -1.47 -0.20 1295.36 1.00 1431 206 139 10 TRUE 1.88
non-small cell lung cancer KRAS_G12D BRCA2 8 12 Asian -0.90 -3.52 0.89 1430.03 1.00 311 8 12 0 TRUE 0.37
non-small cell lung cancer KRAS_G12D BRCA2 123 110 White -0.70 -2.16 0.39 1448.09 1.00 2697 120 107 3 TRUE 0.55
uterine cancer KRAS_G12D BRCA2 38 109 White -0.79 -2.26 0.33 1031.48 1.00 700 35 106 3 TRUE 0.65
colorectal cancer KRAS_G12D BRCA2 265 180 Race:overall -0.81 -1.65 -0.12 1263.40 1.00 1666 253 168 12 TRUE 1.42
non-small cell lung cancer KRAS_G12D BRCA2 131 122 Race:overall -0.76 -2.82 0.85 1444.45 1.00 3008 128 119 3 TRUE 0.38
uterine cancer KRAS_G12D BRCA2 40 120 Race:overall -0.87 -2.97 0.68 1443.99 1.00 756 37 117 3 TRUE 0.46
colorectal cancer KRAS_G12D NOTCH3 22 18 Asian -0.71 -1.42 -0.01 1185.80 1.00 118 20 16 2 TRUE 1.30
colorectal cancer KRAS_G12D NOTCH3 27 12 Black -0.74 -1.52 -0.09 1186.40 1.00 113 26 11 1 TRUE 1.38
colorectal cancer KRAS_G12D NOTCH3 19 13 Unknown -0.74 -1.54 -0.08 1144.99 1.00 98 18 12 1 TRUE 1.36
colorectal cancer KRAS_G12D NOTCH3 215 154 White -0.74 -1.39 -0.22 1142.69 1.00 1414 205 144 10 TRUE 1.87
non-small cell lung cancer KRAS_G12D NOTCH3 123 106 White -0.63 -2.07 0.50 1014.42 1.01 2699 120 103 3 TRUE 0.49
uterine cancer KRAS_G12D NOTCH3 37 72 White -5.93 -15.07 -1.07 1063.70 1.00 707 37 72 0 TRUE 0.92
colorectal cancer KRAS_G12D NOTCH3 283 197 Race:overall -0.73 -1.42 -0.14 1105.53 1.00 1743 269 183 14 TRUE 1.58
non-small cell lung cancer KRAS_G12D NOTCH3 123 106 Race:overall -0.58 -4.98 3.64 1561.49 1.00 2699 120 103 3 TRUE 0.11
uterine cancer KRAS_G12D NOTCH3 37 72 Race:overall -4.35 -11.88 2.49 1312.86 1.00 707 37 72 0 TRUE 0.68
colorectal cancer KRAS_G12D NOTCH4 217 99 White -0.29 -0.99 0.36 1426.14 1.00 1445 207 89 10 TRUE 0.39
non-small cell lung cancer KRAS_G12D NOTCH4 123 117 White -0.34 -1.45 0.62 1395.28 1.00 2687 119 113 4 TRUE 0.28
colorectal cancer KRAS_G12D NOTCH4 217 99 Race:overall -0.29 -4.63 3.62 1466.04 1.00 1445 207 89 10 TRUE 0.05
non-small cell lung cancer KRAS_G12D NOTCH4 123 117 Race:overall -0.21 -4.06 4.33 1364.89 1.00 2687 119 113 4 TRUE 0.04
colorectal cancer KRAS_G12D FGFR3 246 45 White -0.88 -2.26 0.21 918.33 1.00 1647 243 42 3 TRUE 0.78
colorectal cancer KRAS_G12D FGFR3 246 45 Race:overall -0.72 -5.22 3.67 1489.60 1.00 1647 243 42 3 TRUE 0.14
non-small cell lung cancer KRAS_G12D MAP3K13 123 42 White -1.05 -3.84 0.72 1184.08 1.00 2754 122 41 1 FALSE 0.44
non-small cell lung cancer KRAS_G12D MAP3K13 123 42 Race:overall -0.79 -5.21 4.27 1536.34 1.00 2754 122 41 1 FALSE 0.14
colorectal cancer KRAS_G12D IGF1R 215 69 White -0.15 -0.96 0.57 1193.14 1.00 1475 207 61 8 TRUE 0.15
non-small cell lung cancer KRAS_G12D IGF1R 123 39 White -1.01 -3.69 0.91 1539.46 1.00 2756 122 38 1 TRUE 0.40
colorectal cancer KRAS_G12D IGF1R 215 69 Race:overall -0.09 -4.25 4.25 1549.97 1.00 1475 207 61 8 TRUE 0.01
non-small cell lung cancer KRAS_G12D IGF1R 123 39 Race:overall -1.00 -6.03 3.62 1425.01 1.00 2756 122 38 1 TRUE 0.17
cancer of unknown primary KRAS_G12D KEAP1 40 59 White -6.08 -14.89 -1.31 1453.81 1.00 505 40 59 0 FALSE 0.90
non-small cell lung cancer KRAS_G12D KEAP1 8 24 Asian -0.30 -1.40 0.66 1439.10 1.00 299 8 24 0 FALSE 0.25
non-small cell lung cancer KRAS_G12D KEAP1 11 28 Black -0.24 -1.30 0.68 1476.85 1.00 158 10 27 1 FALSE 0.20
non-small cell lung cancer KRAS_G12D KEAP1 9 19 Unknown -0.18 -1.29 0.76 1521.22 1.00 147 8 18 1 FALSE 0.14
non-small cell lung cancer KRAS_G12D KEAP1 123 461 White -0.08 -0.58 0.39 1548.20 1.00 2371 104 442 19 FALSE 0.12
cancer of unknown primary KRAS_G12D KEAP1 40 59 Race:overall -4.40 -11.80 3.16 1458.55 1.00 505 40 59 0 FALSE 0.64
non-small cell lung cancer KRAS_G12D KEAP1 151 532 Race:overall -0.19 -1.03 0.55 1420.43 1.00 2975 130 511 21 FALSE 0.20
colorectal cancer KRAS_G12D KDM5C 27 12 Black -0.32 -2.37 1.06 1418.53 1.00 115 26 11 1 FALSE 0.15
colorectal cancer KRAS_G12D KDM5C 217 51 White 0.54 -0.20 1.19 1387.41 1.00 1490 206 40 11 FALSE 0.90
non-small cell lung cancer KRAS_G12D KDM5C 124 87 White 0.24 -0.84 1.07 1298.30 1.00 2715 119 82 5 FALSE 0.21
uterine cancer KRAS_G12D KDM5C 37 53 White 0.08 -1.40 1.24 1195.64 1.00 723 34 50 3 FALSE 0.04
colorectal cancer KRAS_G12D KDM5C 244 63 Race:overall 0.10 -1.93 1.75 1541.06 1.00 1605 232 51 12 FALSE 0.04
non-small cell lung cancer KRAS_G12D KDM5C 124 87 Race:overall 0.22 -4.30 4.28 1653.00 1.00 2715 119 82 5 FALSE 0.04
uterine cancer KRAS_G12D KDM5C 37 53 Race:overall 0.07 -4.69 4.68 1572.03 1.00 723 34 50 3 FALSE 0.01
cancer of unknown primary KRAS_G12D CDKN2A 40 61 White 0.21 -0.86 1.11 1461.12 1.00 517 35 56 5 TRUE 0.17
non-small cell lung cancer KRAS_G12D CDKN2A 8 15 Asian -0.33 -1.67 0.73 1345.82 1.00 327 8 15 0 TRUE 0.24
non-small cell lung cancer KRAS_G12D CDKN2A 11 18 Black -0.22 -1.40 0.86 1357.88 1.00 171 10 17 1 TRUE 0.16
non-small cell lung cancer KRAS_G12D CDKN2A 9 20 Unknown -0.09 -1.15 1.02 1087.10 1.00 152 7 18 2 TRUE 0.06
non-small cell lung cancer KRAS_G12D CDKN2A 128 218 White -0.36 -1.15 0.32 935.74 1.00 2685 122 212 6 TRUE 0.48
pancreatic cancer KRAS_G12D CDKN2A 19 11 Asian 0.48 -0.12 1.02 1442.12 1.00 54 15 7 4 TRUE 1.08
pancreatic cancer KRAS_G12D CDKN2A 28 15 Unknown 0.48 -0.12 1.01 1503.07 1.00 46 22 9 6 TRUE 1.14
pancreatic cancer KRAS_G12D CDKN2A 424 250 White 0.52 0.25 0.80 1373.22 1.00 725 318 144 106 TRUE 3.76
cancer of unknown primary KRAS_G12D CDKN2A 40 61 Race:overall 0.14 -4.17 4.22 1563.39 1.00 517 35 56 5 TRUE 0.03
non-small cell lung cancer KRAS_G12D CDKN2A 156 271 Race:overall -0.25 -1.20 0.64 1063.51 1.00 3335 147 262 9 TRUE 0.23
pancreatic cancer KRAS_G12D CDKN2A 471 276 Race:overall 0.49 0.03 0.95 1499.82 1.00 825 355 160 116 TRUE 1.48
colorectal cancer KRAS_G12D EPHB1 215 65 White -1.23 -2.58 -0.17 905.21 1.00 1466 212 62 3 FALSE 1.32
non-small cell lung cancer KRAS_G12D EPHB1 11 11 Black -1.20 -3.57 0.31 1221.67 1.00 172 11 11 0 FALSE 0.61
non-small cell lung cancer KRAS_G12D EPHB1 123 135 White -0.97 -2.38 0.11 828.32 1.00 2676 120 132 3 FALSE 0.90
colorectal cancer KRAS_G12D EPHB1 215 65 Race:overall -1.06 -5.26 3.71 1420.59 1.00 1466 212 62 3 FALSE 0.21
non-small cell lung cancer KRAS_G12D EPHB1 134 146 Race:overall -1.06 -3.03 0.37 1123.14 1.00 2848 131 143 3 FALSE 0.68
colorectal cancer KRAS_G12D IRS2 215 71 White 0.13 -0.62 0.78 1249.23 1.00 1472 205 61 10 FALSE 0.14
non-small cell lung cancer KRAS_G12D IRS2 123 68 White -5.83 -15.78 -0.91 1414.90 1.00 2728 123 68 0 FALSE 0.75
uterine cancer KRAS_G12D IRS2 37 55 White -5.76 -17.10 -0.69 1528.32 1.00 714 37 55 0 FALSE 0.70
colorectal cancer KRAS_G12D IRS2 215 71 Race:overall 0.00 -4.21 4.02 1355.36 1.01 1472 205 61 10 FALSE 0.00
non-small cell lung cancer KRAS_G12D IRS2 123 68 Race:overall -4.27 -11.71 2.53 996.24 1.00 2728 123 68 0 FALSE 0.66
uterine cancer KRAS_G12D IRS2 37 55 Race:overall -4.16 -11.25 2.47 1329.73 1.00 714 37 55 0 FALSE 0.67
colorectal cancer KRAS_G12D FANCA 215 51 White 0.04 -0.75 0.82 612.47 1.01 1485 208 44 7 TRUE 0.04
non-small cell lung cancer KRAS_G12D FANCA 123 59 White 0.01 -1.38 1.15 517.49 1.00 2740 120 56 3 TRUE 0.00
colorectal cancer KRAS_G12D FANCA 215 51 Race:overall 0.12 -4.27 4.87 1539.31 1.00 1485 208 44 7 TRUE 0.02
non-small cell lung cancer KRAS_G12D FANCA 123 59 Race:overall 0.06 -4.11 4.68 1276.93 1.00 2740 120 56 3 TRUE 0.01
non-small cell lung cancer KRAS_G12D IL7R 123 69 White -0.61 -2.34 0.67 1427.55 1.00 2734 121 67 2 FALSE 0.36
non-small cell lung cancer KRAS_G12D IL7R 123 69 Race:overall -0.48 -5.01 4.17 1536.59 1.00 2734 121 67 2 FALSE 0.08
uterine cancer KRAS_G12D PPP2R1A 37 133 White -0.98 -2.27 0.10 103.54 1.03 641 34 130 3 FALSE 0.97
uterine cancer KRAS_G12D PPP2R1A 37 133 Race:overall -0.88 -4.87 3.30 1156.81 1.00 641 34 130 3 FALSE 0.21
colorectal cancer KRAS_G12D PIK3CB 215 48 White -2.26 -4.80 -0.54 900.15 1.00 1488 214 47 1 FALSE 1.38
colorectal cancer KRAS_G12D PIK3CB 215 48 Race:overall -1.94 -6.17 3.27 1252.95 1.00 1488 214 47 1 FALSE 0.41
colorectal cancer KRAS_G12D ERBB3 22 11 Asian -0.09 -1.49 0.85 1329.14 1.00 119 21 10 1 TRUE 0.06
colorectal cancer KRAS_G12D ERBB3 216 94 White 0.05 -0.59 0.62 1220.64 1.00 1456 203 81 13 TRUE 0.06
uterine cancer KRAS_G12D ERBB3 37 62 White -0.12 -1.58 1.06 1371.75 1.00 708 34 59 3 TRUE 0.06
colorectal cancer KRAS_G12D ERBB3 238 105 Race:overall -0.01 -1.03 0.87 1318.29 1.00 1575 224 91 14 TRUE 0.00
uterine cancer KRAS_G12D ERBB3 37 62 Race:overall -0.06 -4.54 4.53 1185.82 1.00 708 34 59 3 TRUE 0.01
colorectal cancer KRAS_G12D SMAD4 27 23 Asian 0.00 -0.54 0.51 1489.82 1.00 134 23 19 4 TRUE 0.00
colorectal cancer KRAS_G12D SMAD4 30 27 Black 0.04 -0.46 0.60 1511.97 1.00 104 24 21 6 TRUE 0.06
colorectal cancer KRAS_G12D SMAD4 20 24 Unknown -0.04 -0.62 0.46 1459.42 1.01 89 18 22 2 TRUE 0.06
colorectal cancer KRAS_G12D SMAD4 249 274 White -0.02 -0.37 0.33 1358.54 1.00 1467 214 239 35 TRUE 0.04
non-small cell lung cancer KRAS_G12D SMAD4 8 11 Asian -0.68 -3.15 0.99 1311.02 1.00 332 8 11 0 TRUE 0.28
non-small cell lung cancer KRAS_G12D SMAD4 128 89 White -0.44 -1.82 0.60 809.84 1.00 2796 125 86 3 TRUE 0.33
pancreatic cancer KRAS_G12D SMAD4 19 17 Asian 0.07 -0.63 0.93 1400.57 1.00 49 14 12 5 TRUE 0.07
pancreatic cancer KRAS_G12D SMAD4 419 242 White -0.03 -0.31 0.24 1291.06 1.00 701 342 165 77 TRUE 0.08
colorectal cancer KRAS_G12D SMAD4 326 348 Race:overall -0.01 -0.43 0.42 1409.47 1.00 1794 279 301 47 TRUE 0.02
non-small cell lung cancer KRAS_G12D SMAD4 136 100 Race:overall -0.56 -2.54 0.99 1035.62 1.00 3128 133 97 3 TRUE 0.26
pancreatic cancer KRAS_G12D SMAD4 438 259 Race:overall 0.02 -0.70 0.84 1427.41 1.00 750 356 177 82 TRUE 0.01
colorectal cancer KRAS_G12D ATM 27 17 Asian -0.53 -1.57 0.14 1105.38 1.00 139 27 17 0 TRUE 0.63
colorectal cancer KRAS_G12D ATM 30 15 Black -0.53 -1.69 0.18 1223.42 1.00 113 30 15 0 TRUE 0.55
colorectal cancer KRAS_G12D ATM 20 19 Unknown -0.35 -1.12 0.30 1164.14 1.00 102 17 16 3 TRUE 0.49
colorectal cancer KRAS_G12D ATM 249 176 White -0.28 -0.72 0.16 1283.22 1.00 1562 228 155 21 TRUE 0.63
non-small cell lung cancer KRAS_G12D ATM 8 13 Asian 0.03 -1.33 1.08 1406.00 1.00 330 8 13 0 TRUE 0.02
non-small cell lung cancer KRAS_G12D ATM 11 15 Black -0.02 -1.46 0.95 1440.00 1.00 175 11 15 0 TRUE 0.01
non-small cell lung cancer KRAS_G12D ATM 9 11 Unknown 0.14 -1.04 1.19 1351.36 1.00 161 8 10 1 TRUE 0.10
non-small cell lung cancer KRAS_G12D ATM 130 245 White 0.24 -0.38 0.77 1362.59 1.00 2675 116 231 14 TRUE 0.38
uterine cancer KRAS_G12D ATM 40 132 White 0.05 -0.87 0.85 1224.49 1.00 768 33 125 7 TRUE 0.04
colorectal cancer KRAS_G12D ATM 326 227 Race:overall -0.41 -1.12 0.16 1022.57 1.00 1916 302 203 24 TRUE 0.68
non-small cell lung cancer KRAS_G12D ATM 158 284 Race:overall 0.09 -0.94 0.87 1338.70 1.00 3341 143 269 15 TRUE 0.08
uterine cancer KRAS_G12D ATM 44 150 Race:overall -0.21 -2.79 1.06 1309.00 1.00 839 37 143 7 TRUE 0.09
cancer of unknown primary KRAS_G12D RB1 41 61 White -0.51 -1.91 0.70 1500.86 1.00 519 38 58 3 TRUE 0.36
colorectal cancer KRAS_G12D RB1 247 57 White -0.77 -2.00 0.18 1179.19 1.00 1642 243 53 4 TRUE 0.80
non-small cell lung cancer KRAS_G12D RB1 8 27 Asian -0.76 -2.02 0.26 212.46 1.01 314 8 27 0 TRUE 0.69
non-small cell lung cancer KRAS_G12D RB1 11 18 Black -0.77 -2.07 0.24 293.94 1.01 170 11 18 0 TRUE 0.66
non-small cell lung cancer KRAS_G12D RB1 9 11 Unknown -0.64 -1.85 0.48 377.39 1.00 160 8 10 1 TRUE 0.56
non-small cell lung cancer KRAS_G12D RB1 128 164 White -0.70 -1.81 0.15 182.81 1.01 2726 124 160 4 TRUE 0.80
uterine cancer KRAS_G12D RB1 38 75 White -1.67 -4.65 0.14 1174.91 1.00 788 37 74 1 TRUE 0.80
cancer of unknown primary KRAS_G12D RB1 41 61 Race:overall -0.36 -4.72 3.85 1589.82 1.00 519 38 58 3 TRUE 0.07
colorectal cancer KRAS_G12D RB1 247 57 Race:overall -0.64 -5.17 4.29 1355.60 1.00 1642 243 53 4 TRUE 0.12
non-small cell lung cancer KRAS_G12D RB1 156 220 Race:overall -0.72 -1.82 0.24 251.18 1.01 3370 151 215 5 TRUE 0.75
uterine cancer KRAS_G12D RB1 38 75 Race:overall -1.41 -5.73 3.11 1416.27 1.00 788 37 74 1 TRUE 0.29
cancer of unknown primary KRAS_G12D KMT2D 40 110 White -0.07 -0.98 0.72 1516.29 1.00 486 33 103 7 FALSE 0.06
colorectal cancer KRAS_G12D KMT2D 25 36 Asian -0.33 -0.85 0.20 301.67 1.02 111 21 32 4 FALSE 0.65
colorectal cancer KRAS_G12D KMT2D 27 23 Black -0.33 -0.81 0.20 258.04 1.02 108 24 20 3 FALSE 0.67
colorectal cancer KRAS_G12D KMT2D 21 24 Unknown -0.26 -0.75 0.31 258.23 1.02 97 16 19 5 FALSE 0.45
colorectal cancer KRAS_G12D KMT2D 224 298 White -0.39 -0.76 -0.03 179.21 1.03 1362 198 272 26 FALSE 1.40
non-small cell lung cancer KRAS_G12D KMT2D 8 14 Asian -1.61 -3.48 -0.11 1391.32 1.00 310 8 14 0 FALSE 1.27
non-small cell lung cancer KRAS_G12D KMT2D 11 22 Black -1.64 -3.34 -0.33 1359.26 1.00 164 11 22 0 FALSE 1.45
non-small cell lung cancer KRAS_G12D KMT2D 9 20 Unknown -1.64 -3.48 -0.19 1255.43 1.00 146 9 20 0 FALSE 1.29
non-small cell lung cancer KRAS_G12D KMT2D 124 266 White -1.42 -2.64 -0.50 1114.98 1.00 2571 120 262 4 FALSE 2.01
pancreatic cancer KRAS_G12D KMT2D 408 54 White 0.34 -0.23 0.91 1445.43 1.00 795 386 32 22 FALSE 0.64
uterine cancer KRAS_G12D KMT2D 41 213 White -0.07 -0.78 0.58 568.33 1.01 626 30 202 11 FALSE 0.08
cancer of unknown primary KRAS_G12D KMT2D 40 110 Race:overall 0.01 -4.03 4.35 1528.03 1.00 486 33 103 7 FALSE 0.00
colorectal cancer KRAS_G12D KMT2D 297 381 Race:overall -0.33 -0.74 0.12 160.19 1.02 1678 259 343 38 FALSE 0.83
non-small cell lung cancer KRAS_G12D KMT2D 152 322 Race:overall -1.57 -2.97 -0.37 1130.57 1.00 3191 148 318 4 FALSE 1.70
pancreatic cancer KRAS_G12D KMT2D 408 54 Race:overall 0.26 -4.04 4.45 1343.80 1.00 795 386 32 22 FALSE 0.05
uterine cancer KRAS_G12D KMT2D 50 260 Race:overall -0.38 -1.77 0.54 591.71 1.00 818 39 249 11 FALSE 0.28
colorectal cancer KRAS_G12D TSC2 217 91 White -0.05 -0.72 0.52 1121.12 1.00 1461 206 80 11 TRUE 0.06
non-small cell lung cancer KRAS_G12D TSC2 123 63 White -1.47 -4.22 0.38 1191.04 1.00 2735 122 62 1 TRUE 0.67
uterine cancer KRAS_G12D TSC2 40 62 White 0.95 0.01 1.78 1384.36 1.00 720 33 55 7 TRUE 1.47
colorectal cancer KRAS_G12D TSC2 217 91 Race:overall -0.05 -3.68 4.00 1349.20 1.00 1461 206 80 11 TRUE 0.01
non-small cell lung cancer KRAS_G12D TSC2 123 63 Race:overall -1.25 -6.11 3.80 1394.50 1.00 2735 122 62 1 TRUE 0.23
uterine cancer KRAS_G12D TSC2 40 62 Race:overall 0.80 -3.30 4.78 1415.45 1.00 720 33 55 7 TRUE 0.17
cancer of unknown primary KRAS_G12D APC 43 57 White 0.67 -0.31 1.49 1087.94 1.00 529 36 50 7 TRUE 0.82
colorectal cancer KRAS_G12D APC 36 163 Asian -0.05 -0.56 0.44 1504.15 1.00 65 12 139 24 TRUE 0.07
colorectal cancer KRAS_G12D APC 47 187 Black 0.14 -0.35 0.64 1472.71 1.00 31 8 148 39 TRUE 0.24
colorectal cancer KRAS_G12D APC 12 47 Race:Other 0.00 -0.66 0.56 1487.30 1.00 16 4 39 8 TRUE 0.01
colorectal cancer KRAS_G12D APC 23 156 Unknown -0.17 -0.83 0.38 1268.34 1.00 24 6 139 17 TRUE 0.25
colorectal cancer KRAS_G12D APC 360 1977 White 0.08 -0.16 0.33 1626.75 1.00 576 83 1700 277 TRUE 0.28
non-small cell lung cancer KRAS_G12D APC 8 12 Asian -0.03 -1.16 0.97 1176.20 1.00 330 8 12 0 TRUE 0.02
non-small cell lung cancer KRAS_G12D APC 11 12 Black 0.04 -0.89 1.03 522.14 1.01 177 10 11 1 TRUE 0.03
non-small cell lung cancer KRAS_G12D APC 128 125 White 0.01 -0.73 0.79 366.58 1.02 2769 122 119 6 TRUE 0.01
uterine cancer KRAS_G12D APC 41 108 White 0.22 -0.71 1.07 1159.66 1.00 791 35 102 6 TRUE 0.20
cancer of unknown primary KRAS_G12D APC 43 57 Race:overall 0.63 -3.94 4.79 1458.28 1.00 529 36 50 7 TRUE 0.12
colorectal cancer KRAS_G12D APC 478 2530 Race:overall 0.01 -0.46 0.44 1436.01 1.00 712 113 2165 365 TRUE 0.02
non-small cell lung cancer KRAS_G12D APC 147 149 Race:overall 0.01 -0.89 0.91 444.11 1.01 3276 140 142 7 TRUE 0.01
uterine cancer KRAS_G12D APC 41 108 Race:overall 0.21 -4.00 4.64 1320.95 1.00 791 35 102 6 TRUE 0.04
colorectal cancer KRAS_G12D ERBB2 246 84 White -0.37 -1.19 0.30 354.95 1.01 1617 238 76 8 TRUE 0.46
non-small cell lung cancer KRAS_G12D ERBB2 8 13 Asian -2.22 -5.78 0.22 935.28 1.00 328 8 13 0 TRUE 0.85
non-small cell lung cancer KRAS_G12D ERBB2 128 101 White -2.08 -5.06 -0.25 833.50 1.00 2785 127 100 1 TRUE 0.99
uterine cancer KRAS_G12D ERBB2 39 45 White -0.28 -2.07 1.07 1325.02 1.00 800 37 43 2 TRUE 0.13
colorectal cancer KRAS_G12D ERBB2 246 84 Race:overall -0.33 -4.43 4.18 1453.93 1.00 1617 238 76 8 TRUE 0.06
non-small cell lung cancer KRAS_G12D ERBB2 136 114 Race:overall -2.11 -5.33 0.16 874.75 1.00 3113 135 113 1 TRUE 0.84
uterine cancer KRAS_G12D ERBB2 39 45 Race:overall -0.14 -4.40 5.04 1507.03 1.00 800 37 43 2 TRUE 0.02
colorectal cancer KRAS_G12D JAK1 218 58 White 0.05 -0.89 0.82 732.81 1.00 1481 210 50 8 TRUE 0.04
non-small cell lung cancer KRAS_G12D JAK1 123 41 White -5.30 -15.67 -0.44 908.52 1.00 2754 123 41 0 TRUE 0.56
uterine cancer KRAS_G12D JAK1 41 113 White 0.70 -0.03 1.38 1270.19 1.00 688 31 103 10 TRUE 1.29
colorectal cancer KRAS_G12D JAK1 218 58 Race:overall 0.10 -4.10 4.67 1508.88 1.00 1481 210 50 8 TRUE 0.02
non-small cell lung cancer KRAS_G12D JAK1 123 41 Race:overall -3.71 -11.44 3.05 889.64 1.00 2754 123 41 0 TRUE 0.52
uterine cancer KRAS_G12D JAK1 45 125 Race:overall 0.67 -0.46 1.73 1254.34 1.00 748 34 114 11 TRUE 0.62
uterine cancer KRAS_G12D CCND1 37 55 White 0.69 -0.43 1.67 1372.02 1.00 710 32 50 5 TRUE 0.72
uterine cancer KRAS_G12D CCND1 37 55 Race:overall 0.76 -3.67 5.41 1406.69 1.00 710 32 50 5 TRUE 0.15
colorectal cancer KRAS_G12D ARID2 215 89 White -0.16 -0.85 0.48 1333.44 1.00 1457 205 79 10 FALSE 0.20
non-small cell lung cancer KRAS_G12D ARID2 8 17 Asian -0.49 -2.97 1.09 1331.00 1.00 307 8 17 0 FALSE 0.18
non-small cell lung cancer KRAS_G12D ARID2 123 145 White -0.16 -1.11 0.65 1394.18 1.00 2665 117 139 6 FALSE 0.15
uterine cancer KRAS_G12D ARID2 40 63 White 0.72 -0.36 1.57 1360.61 1.00 719 34 57 6 FALSE 0.89
colorectal cancer KRAS_G12D ARID2 215 89 Race:overall -0.11 -3.95 4.13 1426.02 1.00 1457 205 79 10 FALSE 0.02
non-small cell lung cancer KRAS_G12D ARID2 131 162 Race:overall -0.29 -2.01 1.09 1359.40 1.00 2972 125 156 6 FALSE 0.14
uterine cancer KRAS_G12D ARID2 40 63 Race:overall 0.64 -3.36 5.00 1469.75 1.00 719 34 57 6 FALSE 0.13
colorectal cancer KRAS_G12D SOX17 216 80 White 0.09 -0.66 0.74 1196.73 1.00 1463 205 69 11 FALSE 0.09
non-small cell lung cancer KRAS_G12D SOX17 123 51 White -0.30 -2.05 1.01 1052.10 1.00 2746 121 49 2 FALSE 0.15
colorectal cancer KRAS_G12D SOX17 216 80 Race:overall 0.02 -4.09 4.60 1468.12 1.00 1463 205 69 11 FALSE 0.00
non-small cell lung cancer KRAS_G12D SOX17 123 51 Race:overall -0.23 -4.81 4.14 1563.64 1.00 2746 121 49 2 FALSE 0.04
colorectal cancer KRAS_G12D MTOR 27 12 Black -0.06 -1.10 1.14 1369.22 1.00 114 24 9 3 TRUE 0.04
colorectal cancer KRAS_G12D MTOR 217 111 White -0.42 -1.14 0.18 1471.18 1.00 1439 208 102 9 TRUE 0.68
non-small cell lung cancer KRAS_G12D MTOR 123 92 White -0.94 -2.79 0.37 670.73 1.00 2706 121 90 2 TRUE 0.62
uterine cancer KRAS_G12D MTOR 38 76 White 0.32 -0.70 1.23 1135.66 1.00 703 33 71 5 TRUE 0.28
colorectal cancer KRAS_G12D MTOR 244 123 Race:overall -0.24 -1.31 0.99 1245.64 1.00 1553 232 111 12 TRUE 0.16
non-small cell lung cancer KRAS_G12D MTOR 123 92 Race:overall -0.87 -5.24 3.98 1531.88 1.00 2706 121 90 2 TRUE 0.17
uterine cancer KRAS_G12D MTOR 38 76 Race:overall 0.28 -4.29 4.81 1374.46 1.00 703 33 71 5 TRUE 0.05
non-small cell lung cancer KRAS_G12D RFWD2 123 50 White -0.56 -2.07 0.86 11.32 1.35 2746 121 48 2 FALSE 0.32
non-small cell lung cancer KRAS_G12D RFWD2 123 50 Race:overall -0.56 -3.60 2.98 59.83 1.07 2746 121 48 2 FALSE 0.14
colorectal cancer KRAS_G12D IRS1 216 81 White -0.65 -1.58 0.16 1385.80 1.00 1460 210 75 6 FALSE 0.88
non-small cell lung cancer KRAS_G12D IRS1 123 58 White -5.80 -15.93 -0.72 1071.72 1.00 2738 123 58 0 FALSE 0.72
colorectal cancer KRAS_G12D IRS1 216 81 Race:overall -0.61 -4.94 3.77 1472.86 1.00 1460 210 75 6 FALSE 0.12
non-small cell lung cancer KRAS_G12D IRS1 123 58 Race:overall -4.17 -11.50 2.17 1189.72 1.00 2738 123 58 0 FALSE 0.64
cancer of unknown primary KRAS_G12D NOTCH1 41 43 White -0.64 -2.42 0.71 1485.99 1.00 534 39 41 2 TRUE 0.37
colorectal cancer KRAS_G12D NOTCH1 27 13 Asian -0.46 -1.38 0.25 182.18 1.02 142 27 13 0 TRUE 0.58
colorectal cancer KRAS_G12D NOTCH1 30 13 Black -0.44 -1.32 0.24 213.06 1.01 115 30 13 0 TRUE 0.57
colorectal cancer KRAS_G12D NOTCH1 20 11 Unknown -0.30 -1.06 0.41 353.33 1.01 102 17 8 3 TRUE 0.35
colorectal cancer KRAS_G12D NOTCH1 249 133 White -0.34 -0.91 0.16 149.34 1.02 1594 235 119 14 TRUE 0.64
non-small cell lung cancer KRAS_G12D NOTCH1 11 11 Black -0.21 -1.77 1.33 1388.52 1.00 178 10 10 1 TRUE 0.11
non-small cell lung cancer KRAS_G12D NOTCH1 128 108 White -0.42 -1.60 0.56 1126.01 1.00 2782 125 105 3 TRUE 0.34
uterine cancer KRAS_G12D NOTCH1 38 64 White -0.24 -1.63 0.95 1477.58 1.00 794 35 61 3 TRUE 0.14
cancer of unknown primary KRAS_G12D NOTCH1 41 43 Race:overall -0.62 -5.20 3.62 1483.61 1.00 534 39 41 2 TRUE 0.12
colorectal cancer KRAS_G12D NOTCH1 326 170 Race:overall -0.38 -1.06 0.22 172.12 1.01 1953 309 153 17 TRUE 0.58
non-small cell lung cancer KRAS_G12D NOTCH1 139 119 Race:overall -0.30 -1.71 1.13 1289.68 1.00 2960 135 115 4 TRUE 0.17
uterine cancer KRAS_G12D NOTCH1 42 79 Race:overall -0.54 -3.21 1.28 1422.99 1.00 871 39 76 3 TRUE 0.20
colorectal cancer KRAS_G12D NTRK1 216 46 White -0.23 -1.31 0.69 1010.51 1.00 1486 211 41 5 TRUE 0.19
non-small cell lung cancer KRAS_G12D NTRK1 123 75 White -1.61 -4.29 0.09 959.56 1.00 2722 122 74 1 TRUE 0.81
colorectal cancer KRAS_G12D NTRK1 216 46 Race:overall -0.13 -4.40 4.46 1380.13 1.00 1486 211 41 5 TRUE 0.02
non-small cell lung cancer KRAS_G12D NTRK1 123 75 Race:overall -1.32 -5.74 3.59 1427.59 1.00 2722 122 74 1 TRUE 0.26
non-small cell lung cancer KRAS_G12D INPP4A 123 45 White -5.47 -14.86 -0.61 1076.95 1.00 2750 123 45 0 FALSE 0.77
non-small cell lung cancer KRAS_G12D INPP4A 123 45 Race:overall -3.95 -11.03 2.82 872.04 1.01 2750 123 45 0 FALSE 0.58
colorectal cancer KRAS_G12D CASP8 216 73 White 0.07 -0.63 0.74 1550.01 1.00 1470 206 63 10 FALSE 0.08
colorectal cancer KRAS_G12D CASP8 216 73 Race:overall 0.01 -4.06 4.38 1462.45 1.00 1470 206 63 10 FALSE 0.00
colorectal cancer KRAS_G12D SETD2 217 89 White -0.58 -1.46 0.15 1291.77 1.00 1456 210 82 7 FALSE 0.81
non-small cell lung cancer KRAS_G12D SETD2 8 20 Asian -0.46 -3.27 0.85 1348.36 1.00 305 8 20 0 FALSE 0.18
non-small cell lung cancer KRAS_G12D SETD2 125 185 White -0.09 -0.93 0.63 964.73 1.00 2644 117 177 8 FALSE 0.09
uterine cancer KRAS_G12D SETD2 39 70 White 0.09 -1.16 1.12 1466.36 1.00 713 35 66 4 FALSE 0.06
colorectal cancer KRAS_G12D SETD2 217 89 Race:overall -0.57 -5.12 4.41 1418.16 1.00 1456 210 82 7 FALSE 0.10
non-small cell lung cancer KRAS_G12D SETD2 133 205 Race:overall -0.26 -1.97 0.95 1494.61 1.00 2949 125 197 8 FALSE 0.13
uterine cancer KRAS_G12D SETD2 39 70 Race:overall 0.07 -4.21 4.54 1489.90 1.00 713 35 66 4 FALSE 0.01
colorectal cancer KRAS_G12D PBRM1 218 77 White 0.35 -0.30 0.95 1432.78 1.00 1470 205 64 13 TRUE 0.58
non-small cell lung cancer KRAS_G12D PBRM1 123 95 White 0.14 -0.88 1.00 1393.27 1.00 2716 118 90 5 TRUE 0.11
colorectal cancer KRAS_G12D PBRM1 218 77 Race:overall 0.30 -4.18 4.35 1485.70 1.00 1470 205 64 13 TRUE 0.05
non-small cell lung cancer KRAS_G12D PBRM1 123 95 Race:overall 0.08 -4.14 4.09 1563.32 1.00 2716 118 90 5 TRUE 0.01
colorectal cancer KRAS_G12D EPHA3 22 11 Asian -0.76 -1.84 0.22 1351.87 1.00 121 21 10 1 FALSE 0.85
colorectal cancer KRAS_G12D EPHA3 19 12 Unknown -0.76 -1.82 0.24 1097.02 1.00 100 18 11 1 FALSE 0.83
colorectal cancer KRAS_G12D EPHA3 215 81 White -0.80 -1.72 -0.07 920.04 1.00 1456 210 76 5 FALSE 1.25
non-small cell lung cancer KRAS_G12D EPHA3 11 19 Black -0.59 -1.63 0.41 1190.46 1.00 167 10 18 1 FALSE 0.57
non-small cell lung cancer KRAS_G12D EPHA3 9 13 Unknown -0.56 -1.58 0.43 1163.92 1.00 155 8 12 1 FALSE 0.56
non-small cell lung cancer KRAS_G12D EPHA3 123 199 White -0.67 -1.66 0.12 755.89 1.00 2616 119 195 4 FALSE 0.88
uterine cancer KRAS_G12D EPHA3 37 67 White 0.20 -1.01 1.26 1464.10 1.00 719 33 63 4 FALSE 0.14
colorectal cancer KRAS_G12D EPHA3 256 104 Race:overall -0.78 -1.76 0.11 1152.54 1.00 1677 249 97 7 FALSE 1.00
non-small cell lung cancer KRAS_G12D EPHA3 143 231 Race:overall -0.61 -1.60 0.28 949.41 1.00 2938 137 225 6 FALSE 0.68
uterine cancer KRAS_G12D EPHA3 37 67 Race:overall 0.29 -3.51 4.57 1810.74 1.00 719 33 63 4 FALSE 0.05
colorectal cancer KRAS_G12D KIT 246 38 White -0.36 -1.62 0.66 210.19 1.02 1653 242 34 4 TRUE 0.26
non-small cell lung cancer KRAS_G12D KIT 128 69 White -5.78 -14.50 -0.87 1396.39 1.00 2812 128 69 0 TRUE 0.79
colorectal cancer KRAS_G12D KIT 246 38 Race:overall -0.31 -4.59 4.20 1128.64 1.01 1653 242 34 4 TRUE 0.06
non-small cell lung cancer KRAS_G12D KIT 128 69 Race:overall -4.09 -11.66 2.88 1509.80 1.00 2812 128 69 0 TRUE 0.61
colorectal cancer KRAS_G12D KDR 247 55 White -0.48 -1.57 0.38 1253.68 1.00 1640 242 50 5 TRUE 0.47
non-small cell lung cancer KRAS_G12D KDR 11 11 Black -0.84 -3.42 0.65 1239.38 1.00 178 11 11 0 TRUE 0.35
non-small cell lung cancer KRAS_G12D KDR 129 121 White -0.52 -1.60 0.41 1371.13 1.00 2768 125 117 4 TRUE 0.50
colorectal cancer KRAS_G12D KDR 247 55 Race:overall -0.38 -4.78 3.93 1473.04 1.00 1640 242 50 5 TRUE 0.07
non-small cell lung cancer KRAS_G12D KDR 140 132 Race:overall -0.70 -2.64 0.63 1402.64 1.00 2946 136 128 4 TRUE 0.38
colorectal cancer KRAS_G12D RICTOR 216 60 White -1.16 -2.69 -0.08 1440.27 1.00 1477 213 57 3 FALSE 1.13
non-small cell lung cancer KRAS_G12D RICTOR 123 58 White -1.42 -4.24 0.46 1492.27 1.00 2740 122 57 1 FALSE 0.60
uterine cancer KRAS_G12D RICTOR 37 47 White 0.23 -1.20 1.36 1341.48 1.00 729 34 44 3 FALSE 0.14
colorectal cancer KRAS_G12D RICTOR 216 60 Race:overall -0.93 -4.91 3.92 1441.14 1.00 1477 213 57 3 FALSE 0.18
non-small cell lung cancer KRAS_G12D RICTOR 123 58 Race:overall -1.25 -6.05 3.63 1447.34 1.00 2740 122 57 1 FALSE 0.23
uterine cancer KRAS_G12D RICTOR 37 47 Race:overall 0.24 -4.18 4.80 1449.66 1.00 729 34 44 3 FALSE 0.04
colorectal cancer KRAS_G12D RAD50 215 42 White -0.77 -2.16 0.31 1080.59 1.00 1492 212 39 3 FALSE 0.66
colorectal cancer KRAS_G12D RAD50 215 42 Race:overall -0.69 -5.13 4.13 1540.06 1.00 1492 212 39 3 FALSE 0.13
colorectal cancer KRAS_G12D CSF1R 246 41 White -1.27 -3.18 0.11 1226.77 1.00 1652 244 39 2 TRUE 0.96
non-small cell lung cancer KRAS_G12D CSF1R 128 59 White -1.26 -4.23 0.39 142.19 1.03 2825 127 58 1 TRUE 0.53
colorectal cancer KRAS_G12D CSF1R 246 41 Race:overall -1.04 -5.02 4.03 1311.59 1.00 1652 244 39 2 TRUE 0.20
non-small cell lung cancer KRAS_G12D CSF1R 128 59 Race:overall -1.12 -6.08 3.56 1277.16 1.01 2825 127 58 1 TRUE 0.21
non-small cell lung cancer KRAS_G12D PARK2 123 59 White -0.47 -2.30 0.90 1159.63 1.00 2737 121 57 2 FALSE 0.25
non-small cell lung cancer KRAS_G12D PARK2 123 59 Race:overall -0.44 -5.09 4.03 1422.81 1.00 2737 121 57 2 FALSE 0.07
non-small cell lung cancer KRAS_G12D NTRK2 123 56 White -1.32 -4.24 0.42 1147.84 1.01 2742 122 55 1 FALSE 0.57
non-small cell lung cancer KRAS_G12D NTRK2 123 56 Race:overall -1.11 -5.80 4.14 1409.29 1.00 2742 122 55 1 FALSE 0.20
colorectal cancer KRAS_G12D PTCH1 215 115 White -0.44 -1.13 0.22 1109.77 1.00 1445 205 105 10 TRUE 0.67
non-small cell lung cancer KRAS_G12D PTCH1 123 46 White -0.23 -2.03 1.12 1424.40 1.00 2750 121 44 2 TRUE 0.12
uterine cancer KRAS_G12D PTCH1 37 58 White -0.02 -1.56 1.10 1549.89 1.00 718 34 55 3 TRUE 0.01
colorectal cancer KRAS_G12D PTCH1 215 115 Race:overall -0.43 -4.52 3.70 1385.08 1.00 1445 205 105 10 TRUE 0.08
non-small cell lung cancer KRAS_G12D PTCH1 123 46 Race:overall -0.18 -4.79 4.39 1388.41 1.00 2750 121 44 2 TRUE 0.03
uterine cancer KRAS_G12D PTCH1 37 58 Race:overall -0.04 -4.68 4.67 1633.17 1.00 718 34 55 3 TRUE 0.01
colorectal cancer KRAS_G12D TET1 215 76 White -0.38 -1.21 0.30 1457.43 1.00 1470 208 69 7 FALSE 0.50
non-small cell lung cancer KRAS_G12D TET1 123 101 White -1.95 -4.60 -0.24 1103.78 1.00 2700 122 100 1 FALSE 1.10
colorectal cancer KRAS_G12D TET1 215 76 Race:overall -0.32 -4.61 4.10 1555.82 1.00 1470 208 69 7 FALSE 0.06
non-small cell lung cancer KRAS_G12D TET1 123 101 Race:overall -1.60 -5.64 3.88 1204.88 1.00 2700 122 100 1 FALSE 0.32
colorectal cancer KRAS_G12D FGFR2 246 38 White -2.17 -4.91 -0.38 1416.93 1.00 1650 245 37 1 TRUE 1.17
uterine cancer KRAS_G12D FGFR2 38 83 White -1.84 -4.53 0.02 1425.54 1.00 765 37 82 1 TRUE 0.92
colorectal cancer KRAS_G12D FGFR2 246 38 Race:overall -1.76 -6.34 3.03 1229.54 1.00 1650 245 37 1 TRUE 0.37
uterine cancer KRAS_G12D FGFR2 38 83 Race:overall -1.47 -5.58 3.44 1390.76 1.00 765 37 82 1 TRUE 0.28
colorectal cancer KRAS_G12D TBX3 215 57 White -0.24 -1.14 0.54 1467.91 1.00 1483 209 51 6 FALSE 0.23
non-small cell lung cancer KRAS_G12D TBX3 123 114 White -2.02 -4.72 -0.27 1516.72 1.00 2690 122 113 1 FALSE 1.09
uterine cancer KRAS_G12D TBX3 37 43 White -0.19 -1.96 1.15 1394.26 1.00 727 35 41 2 FALSE 0.09
colorectal cancer KRAS_G12D TBX3 215 57 Race:overall -0.25 -4.54 4.20 1456.65 1.00 1483 209 51 6 FALSE 0.05
non-small cell lung cancer KRAS_G12D TBX3 123 114 Race:overall -1.65 -5.92 3.49 1389.19 1.00 2690 122 113 1 FALSE 0.33
uterine cancer KRAS_G12D TBX3 37 43 Race:overall -0.10 -4.22 4.47 1474.88 1.00 727 35 41 2 FALSE 0.02
colorectal cancer KRAS_G12D HNF1A 246 40 White 0.29 -0.52 1.10 473.78 1.00 1653 239 33 7 TRUE 0.30
colorectal cancer KRAS_G12D HNF1A 246 40 Race:overall 0.21 -4.35 4.47 1375.13 1.00 1653 239 33 7 TRUE 0.04
colorectal cancer KRAS_G12D DICER1 22 12 Asian -0.68 -2.32 0.80 1545.16 1.00 120 21 11 1 TRUE 0.40
colorectal cancer KRAS_G12D DICER1 215 49 White -0.62 -1.68 0.27 1334.96 1.00 1486 211 45 4 TRUE 0.66
non-small cell lung cancer KRAS_G12D DICER1 123 69 White -1.54 -4.31 0.24 1289.66 1.00 2732 122 68 1 TRUE 0.74
uterine cancer KRAS_G12D DICER1 38 64 White -0.70 -2.58 0.69 1340.93 1.00 716 36 62 2 TRUE 0.39
colorectal cancer KRAS_G12D DICER1 237 61 Race:overall -0.65 -2.29 1.11 1614.40 1.00 1606 232 56 5 TRUE 0.36
non-small cell lung cancer KRAS_G12D DICER1 123 69 Race:overall -1.28 -5.55 3.77 1309.97 1.00 2732 122 68 1 TRUE 0.25
uterine cancer KRAS_G12D DICER1 38 64 Race:overall -0.58 -4.77 4.11 1446.48 1.00 716 36 62 2 TRUE 0.10
colorectal cancer KRAS_G12D SMAD3 22 14 Asian 0.22 -1.01 1.16 1158.66 1.00 117 20 12 2 TRUE 0.16
colorectal cancer KRAS_G12D SMAD3 221 84 White 0.30 -0.28 0.85 667.02 1.00 1462 207 70 14 TRUE 0.52
colorectal cancer KRAS_G12D SMAD3 243 98 Race:overall 0.25 -0.97 1.30 1268.76 1.00 1579 227 82 16 TRUE 0.17
colorectal cancer KRAS_G12D NTRK3 215 60 White -0.82 -2.08 0.14 839.93 1.00 1476 211 56 4 FALSE 0.84
non-small cell lung cancer KRAS_G12D NTRK3 8 16 Asian -1.78 -4.39 0.16 1422.26 1.00 306 8 16 0 FALSE 0.93
non-small cell lung cancer KRAS_G12D NTRK3 123 171 White -1.61 -3.40 -0.40 1228.88 1.00 2647 121 169 2 FALSE 1.46
colorectal cancer KRAS_G12D NTRK3 215 60 Race:overall -0.81 -5.33 3.65 1547.48 1.00 1476 211 56 4 FALSE 0.16
non-small cell lung cancer KRAS_G12D NTRK3 131 187 Race:overall -1.67 -3.70 0.01 1470.24 1.00 2953 129 185 2 FALSE 1.05
colorectal cancer KRAS_G12D AXIN1 216 57 White -0.07 -0.97 0.70 1309.90 1.00 1481 209 50 7 FALSE 0.06
colorectal cancer KRAS_G12D AXIN1 216 57 Race:overall 0.04 -4.68 4.70 1558.58 1.00 1481 209 50 7 FALSE 0.01
colorectal cancer KRAS_G12D GRIN2A 22 11 Asian -0.79 -3.79 0.41 948.69 1.00 119 22 11 0 FALSE 0.29
colorectal cancer KRAS_G12D GRIN2A 215 107 White -0.26 -0.99 0.34 358.64 1.01 1440 203 95 12 FALSE 0.36
non-small cell lung cancer KRAS_G12D GRIN2A 123 171 White -0.49 -1.53 0.36 1460.46 1.00 2639 118 166 5 FALSE 0.50
uterine cancer KRAS_G12D GRIN2A 37 65 White -5.89 -16.06 -0.91 1084.56 1.00 714 37 65 0 FALSE 0.75
colorectal cancer KRAS_G12D GRIN2A 237 118 Race:overall -0.50 -2.30 0.63 1161.27 1.00 1559 225 106 12 FALSE 0.27
non-small cell lung cancer KRAS_G12D GRIN2A 123 171 Race:overall -0.44 -4.76 4.29 1425.41 1.00 2639 118 166 5 FALSE 0.08
uterine cancer KRAS_G12D GRIN2A 37 65 Race:overall -4.28 -11.46 2.36 999.47 1.00 714 37 65 0 FALSE 0.64
colorectal cancer KRAS_G12D PALB2 215 44 White -1.31 -3.14 -0.04 1066.23 1.00 1486 213 42 2 TRUE 1.06
non-small cell lung cancer KRAS_G12D PALB2 123 47 White -0.24 -2.12 1.06 1428.27 1.00 2751 121 45 2 TRUE 0.12
colorectal cancer KRAS_G12D PALB2 215 44 Race:overall -1.09 -5.08 3.71 1404.42 1.00 1486 213 42 2 TRUE 0.22
non-small cell lung cancer KRAS_G12D PALB2 123 47 Race:overall -0.20 -4.74 4.62 1435.28 1.00 2751 121 45 2 TRUE 0.03
colorectal cancer KRAS_G12D CTCF 216 71 White 0.34 -0.36 0.97 1276.97 1.00 1476 204 59 12 FALSE 0.50
uterine cancer KRAS_G12D CTCF 38 137 White 0.30 -0.52 1.06 773.69 1.01 645 29 128 9 FALSE 0.35
colorectal cancer KRAS_G12D CTCF 216 71 Race:overall 0.36 -3.90 4.44 1585.54 1.00 1476 204 59 12 FALSE 0.07
uterine cancer KRAS_G12D CTCF 42 148 Race:overall 0.06 -1.98 1.27 852.66 1.00 703 33 139 9 FALSE 0.03
colorectal cancer KRAS_G12D CDH1 247 43 White -0.18 -1.24 0.74 709.25 1.00 1653 242 38 5 TRUE 0.14
colorectal cancer KRAS_G12D CDH1 247 43 Race:overall -0.23 -4.39 3.84 1562.74 1.00 1653 242 38 5 TRUE 0.04
colorectal cancer KRAS_G12D CDK12 216 76 White -0.41 -1.31 0.37 1324.86 1.00 1470 209 69 7 FALSE 0.48
non-small cell lung cancer KRAS_G12D CDK12 123 45 White -1.16 -3.80 0.67 1052.23 1.00 2750 122 44 1 FALSE 0.48
colorectal cancer KRAS_G12D CDK12 216 76 Race:overall -0.36 -4.70 4.35 1481.24 1.00 1470 209 69 7 FALSE 0.06
non-small cell lung cancer KRAS_G12D CDK12 123 45 Race:overall -0.98 -5.91 3.96 1390.37 1.00 2750 122 44 1 FALSE 0.17
cancer of unknown primary KRAS_G12D STK11 40 44 White -5.87 -15.27 -0.93 306.84 1.01 526 40 44 0 TRUE 0.81
non-small cell lung cancer KRAS_G12D STK11 8 19 Asian 0.32 -0.88 1.40 1309.06 1.00 329 7 18 1 TRUE 0.23
non-small cell lung cancer KRAS_G12D STK11 11 30 Black 0.10 -1.12 1.19 1454.12 1.00 159 10 29 1 TRUE 0.07
non-small cell lung cancer KRAS_G12D STK11 9 15 Unknown 0.24 -1.02 1.36 1466.42 1.00 156 8 14 1 TRUE 0.16
non-small cell lung cancer KRAS_G12D STK11 129 472 White 0.40 -0.02 0.81 1538.38 1.00 2448 101 444 28 TRUE 1.23
cancer of unknown primary KRAS_G12D STK11 40 44 Race:overall -4.48 -11.69 2.52 249.33 1.01 526 40 44 0 TRUE 0.66
non-small cell lung cancer KRAS_G12D STK11 157 536 Race:overall 0.27 -0.63 1.09 1497.13 1.00 3092 126 505 31 TRUE 0.26
colorectal cancer KRAS_G12D DNMT1 217 71 White -0.31 -1.14 0.46 1382.60 1.00 1469 210 64 7 FALSE 0.35
colorectal cancer KRAS_G12D DNMT1 217 71 Race:overall -0.28 -4.62 3.75 1468.55 1.00 1469 210 64 7 FALSE 0.05
colorectal cancer KRAS_G12D BRD4 217 69 White 0.01 -0.75 0.70 1453.51 1.00 1468 208 60 9 FALSE 0.01
non-small cell lung cancer KRAS_G12D BRD4 123 40 White -5.45 -14.00 -0.46 1223.58 1.00 2756 123 40 0 FALSE 0.76
uterine cancer KRAS_G12D BRD4 38 56 White -0.02 -1.43 1.19 943.68 1.00 714 35 53 3 FALSE 0.01
colorectal cancer KRAS_G12D BRD4 217 69 Race:overall -0.08 -4.29 3.94 1339.23 1.00 1468 208 60 9 FALSE 0.01
non-small cell lung cancer KRAS_G12D BRD4 123 40 Race:overall -3.90 -10.87 2.95 1309.54 1.00 2756 123 40 0 FALSE 0.60
uterine cancer KRAS_G12D BRD4 38 56 Race:overall 0.00 -4.21 4.44 1306.99 1.00 714 35 53 3 FALSE 0.00
colorectal cancer KRAS_G12D ASXL1 215 85 White -1.04 -1.98 -0.09 32.51 1.05 1454 210 80 5 TRUE 1.31
non-small cell lung cancer KRAS_G12D ASXL1 123 74 White -0.70 -2.75 0.65 1028.19 1.00 2736 121 72 2 TRUE 0.40
uterine cancer KRAS_G12D ASXL1 39 49 White 0.51 -0.82 1.58 1100.74 1.00 725 35 45 4 TRUE 0.41
colorectal cancer KRAS_G12D ASXL1 215 85 Race:overall -0.85 -4.39 3.62 931.28 1.00 1454 210 80 5 TRUE 0.18
non-small cell lung cancer KRAS_G12D ASXL1 123 74 Race:overall -0.60 -5.32 4.25 1446.63 1.00 2736 121 72 2 TRUE 0.11
uterine cancer KRAS_G12D ASXL1 39 49 Race:overall 0.49 -3.83 4.76 1444.06 1.00 725 35 45 4 TRUE 0.09
colorectal cancer KRAS_G12D EP300 216 107 White -0.78 -1.65 -0.06 1374.34 1.00 1445 209 100 7 TRUE 1.26
non-small cell lung cancer KRAS_G12D EP300 123 91 White -0.91 -2.65 0.39 1401.19 1.00 2715 121 89 2 TRUE 0.62
uterine cancer KRAS_G12D EP300 38 81 White -0.07 -1.26 0.96 197.76 1.02 700 34 77 4 TRUE 0.04
colorectal cancer KRAS_G12D EP300 216 107 Race:overall -0.65 -4.92 3.66 1669.66 1.00 1445 209 100 7 TRUE 0.13
non-small cell lung cancer KRAS_G12D EP300 123 91 Race:overall -0.77 -5.26 4.14 1515.91 1.00 2715 121 89 2 TRUE 0.14
uterine cancer KRAS_G12D EP300 38 81 Race:overall -0.09 -4.22 4.04 1271.54 1.00 700 34 77 4 TRUE 0.02
colorectal cancer KRAS_G12D ERBB4 19 13 Unknown 0.22 -0.74 1.28 1412.49 1.00 103 16 10 3 TRUE 0.18
colorectal cancer KRAS_G12D ERBB4 246 109 White -0.04 -0.61 0.49 862.24 1.00 1602 233 96 13 TRUE 0.06
non-small cell lung cancer KRAS_G12D ERBB4 11 17 Black -0.66 -3.76 0.75 959.20 1.01 173 11 17 0 TRUE 0.23
non-small cell lung cancer KRAS_G12D ERBB4 128 160 White -0.12 -1.01 0.64 1384.24 1.00 2752 121 153 7 TRUE 0.11
colorectal cancer KRAS_G12D ERBB4 265 122 Race:overall 0.10 -0.96 1.25 1284.79 1.00 1705 249 106 16 TRUE 0.07
non-small cell lung cancer KRAS_G12D ERBB4 139 177 Race:overall -0.38 -2.47 0.93 998.14 1.00 2925 132 170 7 TRUE 0.17
colorectal cancer KRAS_G12D MDC1 215 51 White -0.99 -2.39 0.18 344.30 1.01 1484 212 48 3 FALSE 0.86
non-small cell lung cancer KRAS_G12D MDC1 9 13 Unknown -1.42 -5.15 0.79 1150.26 1.00 157 9 13 0 FALSE 0.46
non-small cell lung cancer KRAS_G12D MDC1 123 73 White -0.83 -2.53 0.51 1316.60 1.00 2729 121 71 2 FALSE 0.52
colorectal cancer KRAS_G12D MDC1 215 51 Race:overall -0.91 -4.93 3.71 1169.81 1.00 1484 212 48 3 FALSE 0.18
non-small cell lung cancer KRAS_G12D MDC1 132 86 Race:overall -1.08 -3.90 0.91 1084.28 1.00 2886 130 84 2 FALSE 0.41
colorectal cancer KRAS_G12D RECQL4 215 64 White 0.23 -0.52 0.90 1162.95 1.00 1479 205 54 10 TRUE 0.28
non-small cell lung cancer KRAS_G12D RECQL4 123 50 White -6.03 -16.77 -0.59 757.64 1.00 2746 123 50 0 TRUE 0.50
colorectal cancer KRAS_G12D RECQL4 215 64 Race:overall 0.24 -4.20 4.62 1485.77 1.00 1479 205 54 10 TRUE 0.04
non-small cell lung cancer KRAS_G12D RECQL4 123 50 Race:overall -4.02 -11.43 2.90 1344.00 1.00 2746 123 50 0 TRUE 0.58
colorectal cancer KRAS_G12D MED12 216 95 White -0.65 -1.57 0.08 689.98 1.00 1452 209 88 7 TRUE 0.92
non-small cell lung cancer KRAS_G12D MED12 123 146 White -0.57 -1.77 0.35 1112.17 1.00 2664 119 142 4 TRUE 0.54
uterine cancer KRAS_G12D MED12 37 107 White -2.40 -4.97 -0.63 1012.92 1.00 680 37 107 0 TRUE 1.47
colorectal cancer KRAS_G12D MED12 216 95 Race:overall -0.51 -4.68 4.05 1360.46 1.00 1452 209 88 7 TRUE 0.10
non-small cell lung cancer KRAS_G12D MED12 123 146 Race:overall -0.57 -4.72 3.64 1532.20 1.00 2664 119 142 4 TRUE 0.11
uterine cancer KRAS_G12D MED12 44 131 Race:overall -2.27 -4.85 -0.34 1001.03 1.00 821 43 130 1 TRUE 1.29
colorectal cancer KRAS_G12D ERCC5 215 46 White -0.90 -2.30 0.19 1436.76 1.00 1484 212 43 3 TRUE 0.80
non-small cell lung cancer KRAS_G12D ERCC5 123 57 White -0.47 -2.22 0.85 821.71 1.00 2742 121 55 2 TRUE 0.25
uterine cancer KRAS_G12D ERCC5 40 41 White 1.23 0.15 2.11 1377.22 1.00 732 34 35 6 TRUE 1.91
colorectal cancer KRAS_G12D ERCC5 215 46 Race:overall -0.77 -5.13 4.27 1381.09 1.00 1484 212 43 3 TRUE 0.14
non-small cell lung cancer KRAS_G12D ERCC5 123 57 Race:overall -0.36 -4.83 4.12 1415.36 1.00 2742 121 55 2 TRUE 0.06
uterine cancer KRAS_G12D ERCC5 40 41 Race:overall 1.10 -3.73 5.46 1172.28 1.00 732 34 35 6 TRUE 0.22
colorectal cancer KRAS_G12D PIK3CD 216 58 White -0.50 -1.50 0.37 1301.89 1.00 1477 211 53 5 FALSE 0.51
colorectal cancer KRAS_G12D PIK3CD 216 58 Race:overall -0.43 -5.16 4.10 1428.00 1.00 1477 211 53 5 FALSE 0.08
colorectal cancer KRAS_G12D BRCA1 215 56 White 0.13 -0.68 0.87 1256.29 1.00 1484 207 48 8 TRUE 0.13
non-small cell lung cancer KRAS_G12D BRCA1 123 79 White -0.29 -1.64 0.82 1062.72 1.00 2722 120 76 3 TRUE 0.20
colorectal cancer KRAS_G12D BRCA1 215 56 Race:overall 0.09 -4.19 4.59 1371.69 1.00 1484 207 48 8 TRUE 0.02
non-small cell lung cancer KRAS_G12D BRCA1 123 79 Race:overall -0.27 -4.74 4.49 1275.72 1.00 2722 120 76 3 TRUE 0.05
colorectal cancer KRAS_G12D RBM10 215 54 White 0.17 -0.70 0.91 880.71 1.00 1484 207 46 8 FALSE 0.17
non-small cell lung cancer KRAS_G12D RBM10 8 36 Asian 0.44 -0.89 1.16 1061.70 1.00 287 8 36 0 FALSE 0.40
non-small cell lung cancer KRAS_G12D RBM10 11 16 Black 0.47 -0.94 1.21 865.82 1.00 168 11 16 0 FALSE 0.43
non-small cell lung cancer KRAS_G12D RBM10 9 15 Unknown 0.57 -0.51 1.26 1122.01 1.00 152 8 14 1 FALSE 0.70
non-small cell lung cancer KRAS_G12D RBM10 127 314 White 0.78 0.37 1.22 1276.09 1.00 2521 98 285 29 FALSE 3.51
uterine cancer KRAS_G12D RBM10 37 46 White 0.24 -1.12 1.38 1182.26 1.00 726 34 43 3 FALSE 0.14
colorectal cancer KRAS_G12D RBM10 215 54 Race:overall 0.17 -4.41 4.39 1323.68 1.00 1484 207 46 8 FALSE 0.03
non-small cell lung cancer KRAS_G12D RBM10 155 381 Race:overall 0.56 -0.38 1.13 947.42 1.00 3128 125 351 30 FALSE 0.84
uterine cancer KRAS_G12D RBM10 37 46 Race:overall 0.12 -4.60 4.13 1498.13 1.00 726 34 43 3 FALSE 0.02
colorectal cancer KRAS_G12D TSC1 215 60 White 0.20 -0.55 0.87 1579.24 1.00 1486 206 51 9 TRUE 0.24
non-small cell lung cancer KRAS_G12D TSC1 123 44 White -5.53 -14.94 0.66 130.79 1.03 2751 123 44 0 TRUE 0.55
uterine cancer KRAS_G12D TSC1 39 51 White 0.74 -0.32 1.63 1392.38 1.00 727 34 46 5 TRUE 0.87
colorectal cancer KRAS_G12D TSC1 215 60 Race:overall 0.22 -4.14 5.01 1503.88 1.00 1486 206 51 9 TRUE 0.04
non-small cell lung cancer KRAS_G12D TSC1 123 44 Race:overall -4.12 -11.74 2.62 86.43 1.03 2751 123 44 0 TRUE 0.57
uterine cancer KRAS_G12D TSC1 39 51 Race:overall 0.65 -4.21 4.90 1550.18 1.00 727 34 46 5 TRUE 0.12
colorectal cancer KRAS_G12D FLCN 216 45 White -0.48 -1.70 0.46 1083.52 1.00 1488 212 41 4 TRUE 0.40
colorectal cancer KRAS_G12D FLCN 216 45 Race:overall -0.44 -4.89 3.98 1443.22 1.00 1488 212 41 4 TRUE 0.08
cancer of unknown primary KRAS_G12D NF1 40 49 White -1.70 -4.48 0.07 1379.88 1.00 517 39 48 1 TRUE 0.84
colorectal cancer KRAS_G12D NF1 216 113 White -0.45 -1.13 0.18 1115.88 1.00 1449 206 103 10 TRUE 0.73
non-small cell lung cancer KRAS_G12D NF1 8 21 Asian -0.73 -1.83 0.10 140.69 1.03 301 8 21 0 TRUE 0.93
non-small cell lung cancer KRAS_G12D NF1 11 18 Black -0.69 -1.76 0.08 182.79 1.02 168 10 17 1 TRUE 0.90
non-small cell lung cancer KRAS_G12D NF1 9 14 Unknown -0.72 -1.79 0.12 157.90 1.02 152 9 14 0 TRUE 0.91
non-small cell lung cancer KRAS_G12D NF1 123 254 White -0.70 -1.56 -0.06 118.08 1.03 2587 117 248 6 TRUE 1.11
uterine cancer KRAS_G12D NF1 37 111 White -0.37 -1.64 0.66 1412.98 1.00 698 33 107 4 TRUE 0.28
cancer of unknown primary KRAS_G12D NF1 40 49 Race:overall -1.36 -5.98 3.41 1506.60 1.00 517 39 48 1 TRUE 0.26
colorectal cancer KRAS_G12D NF1 216 113 Race:overall -0.32 -4.55 4.48 1577.03 1.00 1449 206 103 10 TRUE 0.06
non-small cell lung cancer KRAS_G12D NF1 151 307 Race:overall -0.71 -1.67 0.02 137.53 1.03 3208 144 300 7 TRUE 1.00
uterine cancer KRAS_G12D NF1 37 111 Race:overall -0.30 -4.47 4.55 1443.10 1.00 698 33 107 4 TRUE 0.05
colorectal cancer KRAS_G12D FLT1 217 68 White -0.14 -0.93 0.60 578.08 1.01 1475 209 60 8 FALSE 0.13
non-small cell lung cancer KRAS_G12D FLT1 123 118 White -1.20 -3.05 0.12 1342.09 1.00 2689 121 116 2 FALSE 0.89
uterine cancer KRAS_G12D FLT1 37 45 White -5.57 -14.81 -0.64 1233.03 1.00 727 37 45 0 FALSE 0.79
colorectal cancer KRAS_G12D FLT1 217 68 Race:overall -0.13 -4.83 4.13 1361.70 1.00 1475 209 60 8 FALSE 0.02
non-small cell lung cancer KRAS_G12D FLT1 123 118 Race:overall -1.01 -5.42 3.90 1583.98 1.00 2689 121 116 2 FALSE 0.20
uterine cancer KRAS_G12D FLT1 37 45 Race:overall -4.18 -11.22 2.25 773.57 1.00 727 37 45 0 FALSE 0.65
colorectal cancer KRAS_G12D RPTOR 216 52 White 0.05 -0.77 0.82 1254.99 1.00 1482 209 45 7 FALSE 0.04
non-small cell lung cancer KRAS_G12D RPTOR 123 58 White -5.66 -15.49 -0.63 1012.36 1.00 2738 123 58 0 FALSE 0.76
colorectal cancer KRAS_G12D RPTOR 216 52 Race:overall 0.13 -4.47 4.53 1510.42 1.00 1482 209 45 7 FALSE 0.02
non-small cell lung cancer KRAS_G12D RPTOR 123 58 Race:overall -4.18 -11.63 2.71 1194.77 1.00 2738 123 58 0 FALSE 0.62
colorectal cancer KRAS_G12D RASA1 215 58 White -0.50 -1.52 0.35 1220.11 1.00 1485 210 53 5 FALSE 0.53
non-small cell lung cancer KRAS_G12D RASA1 123 84 White -0.34 -1.77 0.79 806.04 1.00 2714 120 81 3 FALSE 0.22
uterine cancer KRAS_G12D RASA1 37 81 White -5.25 -12.58 -0.82 165.57 1.03 710 37 81 0 FALSE 1.04
colorectal cancer KRAS_G12D RASA1 215 58 Race:overall -0.38 -4.66 4.43 1467.60 1.00 1485 210 53 5 FALSE 0.07
non-small cell lung cancer KRAS_G12D RASA1 123 84 Race:overall -0.28 -4.78 4.24 1338.95 1.00 2714 120 81 3 FALSE 0.05
uterine cancer KRAS_G12D RASA1 41 92 Race:overall -5.11 -12.10 -0.72 157.19 1.03 769 41 92 0 FALSE 1.01
colorectal cancer KRAS_G12D EPHA5 22 11 Asian -0.53 -1.50 0.21 870.98 1.00 124 21 10 1 FALSE 0.67
colorectal cancer KRAS_G12D EPHA5 19 12 Unknown -0.59 -1.61 0.16 1097.52 1.00 100 19 12 0 FALSE 0.67
colorectal cancer KRAS_G12D EPHA5 216 115 White -0.47 -1.10 0.10 842.44 1.00 1436 205 104 11 FALSE 0.87
non-small cell lung cancer KRAS_G12D EPHA5 8 12 Asian -0.87 -2.30 0.27 1120.19 1.00 310 8 12 0 FALSE 0.74
non-small cell lung cancer KRAS_G12D EPHA5 11 18 Black -0.90 -2.34 0.16 1123.23 1.00 168 11 18 0 FALSE 0.79
non-small cell lung cancer KRAS_G12D EPHA5 9 12 Unknown -0.90 -2.32 0.25 909.53 1.00 154 9 12 0 FALSE 0.75
non-small cell lung cancer KRAS_G12D EPHA5 123 213 White -0.71 -1.61 0.12 843.99 1.00 2606 117 207 6 FALSE 0.94
uterine cancer KRAS_G12D EPHA5 39 78 White -0.38 -1.90 0.82 1339.05 1.00 711 36 75 3 FALSE 0.23
colorectal cancer KRAS_G12D EPHA5 257 138 Race:overall -0.53 -1.34 0.14 1055.17 1.00 1660 245 126 12 FALSE 0.77
non-small cell lung cancer KRAS_G12D EPHA5 151 255 Race:overall -0.84 -2.03 0.17 1014.70 1.00 3238 145 249 6 FALSE 0.90
uterine cancer KRAS_G12D EPHA5 39 78 Race:overall -0.34 -4.43 4.08 1450.37 1.00 711 36 75 3 FALSE 0.06
colorectal cancer KRAS_G12D AR 215 86 White -0.53 -1.38 0.21 1353.65 1.00 1450 208 79 7 TRUE 0.73
non-small cell lung cancer KRAS_G12D AR 11 13 Black -0.04 -1.80 1.38 1697.66 1.00 173 10 12 1 TRUE 0.02
non-small cell lung cancer KRAS_G12D AR 123 80 White -0.20 -1.37 0.78 1372.97 1.00 2722 120 77 3 TRUE 0.14
uterine cancer KRAS_G12D AR 37 51 White 0.07 -2.19 1.28 102.33 1.03 721 34 48 3 TRUE 0.03
colorectal cancer KRAS_G12D AR 215 86 Race:overall -0.42 -4.36 4.11 1496.97 1.00 1450 208 79 7 TRUE 0.08
non-small cell lung cancer KRAS_G12D AR 134 93 Race:overall -0.12 -1.77 1.42 1567.84 1.00 2895 130 89 4 TRUE 0.05
uterine cancer KRAS_G12D AR 37 51 Race:overall 0.03 -4.31 4.48 685.92 1.00 721 34 48 3 TRUE 0.01
colorectal cancer KRAS_G12D GNAS 246 66 White 0.28 -0.44 0.92 1366.50 1.00 1635 235 55 11 TRUE 0.38
pancreatic cancer KRAS_G12D GNAS 417 53 White -0.67 -1.39 -0.03 1475.54 1.00 821 406 42 11 TRUE 1.25
colorectal cancer KRAS_G12D GNAS 246 66 Race:overall 0.21 -4.29 4.72 1486.08 1.00 1635 235 55 11 TRUE 0.04
pancreatic cancer KRAS_G12D GNAS 417 53 Race:overall -0.53 -4.61 3.88 1319.16 1.00 821 406 42 11 TRUE 0.10
colorectal cancer KRAS_G12D ASXL2 215 60 White -1.66 -3.45 -0.31 1353.87 1.00 1485 213 58 2 FALSE 1.46
non-small cell lung cancer KRAS_G12D ASXL2 123 53 White -1.31 -4.04 0.63 653.10 1.00 2745 122 52 1 FALSE 0.56
colorectal cancer KRAS_G12D ASXL2 215 60 Race:overall -1.34 -5.34 3.31 1405.82 1.00 1485 213 58 2 FALSE 0.28
non-small cell lung cancer KRAS_G12D ASXL2 123 53 Race:overall -1.16 -5.72 3.81 1312.89 1.00 2745 122 52 1 FALSE 0.21
colorectal cancer KRAS_G12D SF3B1 215 51 White -1.49 -3.34 -0.17 1296.91 1.00 1485 213 49 2 TRUE 1.22
non-small cell lung cancer KRAS_G12D SF3B1 123 71 White -0.64 -2.45 0.62 1132.64 1.00 2728 121 69 2 TRUE 0.38
colorectal cancer KRAS_G12D SF3B1 215 51 Race:overall -1.34 -5.70 3.29 1479.28 1.00 1485 213 49 2 TRUE 0.27
non-small cell lung cancer KRAS_G12D SF3B1 123 71 Race:overall -0.57 -5.06 4.24 1437.15 1.00 2728 121 69 2 TRUE 0.10
colorectal cancer KRAS_G12D MLH1 246 49 White -0.60 -1.87 0.38 1182.18 1.00 1649 242 45 4 TRUE 0.54
colorectal cancer KRAS_G12D MLH1 246 49 Race:overall -0.52 -4.85 3.94 1526.07 1.00 1649 242 45 4 TRUE 0.09
colorectal cancer KRAS_G12D ROS1 22 16 Asian -1.90 -5.81 0.02 1248.08 1.00 117 22 16 0 TRUE 0.63
colorectal cancer KRAS_G12D ROS1 215 71 White -0.66 -1.59 0.16 1461.88 1.00 1466 209 65 6 TRUE 0.86
non-small cell lung cancer KRAS_G12D ROS1 123 93 White -1.99 -5.46 -0.15 163.74 1.01 2707 122 92 1 TRUE 0.77
uterine cancer KRAS_G12D ROS1 38 79 White -0.35 -1.84 0.81 1215.57 1.00 720 35 76 3 TRUE 0.22
colorectal cancer KRAS_G12D ROS1 237 87 Race:overall -1.17 -3.95 0.79 1535.67 1.00 1583 231 81 6 TRUE 0.50
non-small cell lung cancer KRAS_G12D ROS1 123 93 Race:overall -1.73 -7.58 3.37 329.00 1.00 2707 122 92 1 TRUE 0.32
uterine cancer KRAS_G12D ROS1 38 79 Race:overall -0.32 -4.68 4.02 1621.11 1.00 720 35 76 3 TRUE 0.06
colorectal cancer KRAS_G12D PIK3R2 215 36 White 0.03 -1.03 0.91 1322.03 1.00 1495 210 31 5 FALSE 0.02
colorectal cancer KRAS_G12D PIK3R2 215 36 Race:overall -0.04 -4.75 4.21 1426.33 1.00 1495 210 31 5 FALSE 0.01
colorectal cancer KRAS_G12D FLT3 246 36 White -1.17 -3.16 0.20 888.12 1.00 1655 244 34 2 TRUE 0.79
non-small cell lung cancer KRAS_G12D FLT3 129 62 White -0.04 -1.34 1.04 1236.92 1.00 2824 126 59 3 TRUE 0.02
uterine cancer KRAS_G12D FLT3 38 53 White -1.24 -3.85 0.55 1329.19 1.00 805 37 52 1 TRUE 0.58
colorectal cancer KRAS_G12D FLT3 246 36 Race:overall -1.04 -5.32 3.52 1467.92 1.00 1655 244 34 2 TRUE 0.21
non-small cell lung cancer KRAS_G12D FLT3 129 62 Race:overall 0.00 -4.66 4.24 1494.01 1.00 2824 126 59 3 TRUE 0.00
uterine cancer KRAS_G12D FLT3 38 53 Race:overall -1.02 -5.52 3.97 1553.50 1.00 805 37 52 1 TRUE 0.20
colorectal cancer KRAS_G12D MSH2 215 63 White -0.37 -1.26 0.45 1339.49 1.00 1485 209 57 6 TRUE 0.38
non-small cell lung cancer KRAS_G12D MSH2 123 45 White -0.18 -1.86 1.11 1378.18 1.00 2755 121 43 2 TRUE 0.09
uterine cancer KRAS_G12D MSH2 38 51 White 0.07 -1.26 1.22 700.00 1.00 725 35 48 3 TRUE 0.04
colorectal cancer KRAS_G12D MSH2 215 63 Race:overall -0.30 -4.80 4.45 1602.68 1.00 1485 209 57 6 TRUE 0.05
non-small cell lung cancer KRAS_G12D MSH2 123 45 Race:overall -0.12 -4.41 4.23 1257.26 1.00 2755 121 43 2 TRUE 0.02
uterine cancer KRAS_G12D MSH2 38 51 Race:overall 0.04 -4.00 4.09 1392.21 1.00 725 35 48 3 TRUE 0.01
non-small cell lung cancer KRAS_G12D DIS3 123 53 White -0.41 -2.33 0.87 1058.12 1.00 2744 121 51 2 FALSE 0.21
non-small cell lung cancer KRAS_G12D DIS3 123 53 Race:overall -0.36 -4.95 4.70 1376.43 1.00 2744 121 51 2 FALSE 0.06
colorectal cancer KRAS_G12D AXL 215 67 White -0.26 -1.12 0.47 1330.12 1.00 1475 208 60 7 FALSE 0.27
colorectal cancer KRAS_G12D AXL 215 67 Race:overall -0.24 -4.64 4.25 1197.11 1.00 1475 208 60 7 FALSE 0.04
pancreatic cancer KRAS_G12D DAXX 406 46 White -3.57 -6.22 -1.78 504.32 1.00 782 405 45 1 TRUE 2.60
pancreatic cancer KRAS_G12D DAXX 406 46 Race:overall -2.91 -6.94 2.68 1233.69 1.00 782 405 45 1 TRUE 0.67
colorectal cancer KRAS_G12D PIK3CG 217 89 White 0.11 -0.61 0.76 80.72 1.04 1455 205 77 12 FALSE 0.12
non-small cell lung cancer KRAS_G12D PIK3CG 11 12 Black -1.64 -4.08 -0.09 852.85 1.01 172 11 12 0 FALSE 0.95
non-small cell lung cancer KRAS_G12D PIK3CG 123 151 White -1.52 -3.21 -0.37 694.89 1.01 2660 121 149 2 FALSE 1.59
uterine cancer KRAS_G12D PIK3CG 38 43 White 0.28 -1.14 1.38 1306.53 1.00 729 35 40 3 FALSE 0.18
colorectal cancer KRAS_G12D PIK3CG 217 89 Race:overall 0.19 -3.75 4.27 1395.30 1.00 1455 205 77 12 FALSE 0.04
non-small cell lung cancer KRAS_G12D PIK3CG 134 163 Race:overall -1.55 -3.58 -0.07 740.22 1.01 2832 132 161 2 FALSE 1.16
uterine cancer KRAS_G12D PIK3CG 38 43 Race:overall 0.30 -3.97 4.63 1523.86 1.00 729 35 40 3 FALSE 0.05
colorectal cancer KRAS_G12D MAP2K4 216 53 White -1.03 -2.42 0.06 963.64 1.00 1476 213 50 3 TRUE 1.01
colorectal cancer KRAS_G12D MAP2K4 216 53 Race:overall -0.87 -5.08 3.50 1200.59 1.00 1476 213 50 3 TRUE 0.18
colorectal cancer KRAS_G12D EGFR 246 59 White -1.15 -2.55 -0.10 914.79 1.00 1636 243 56 3 TRUE 1.18
non-small cell lung cancer KRAS_G12D EGFR 8 209 Asian -3.00 -4.75 -1.56 1609.77 1.00 168 7 208 1 TRUE 3.76
non-small cell lung cancer KRAS_G12D EGFR 11 69 Black -3.27 -5.30 -1.64 1647.30 1.00 134 11 69 0 TRUE 3.45
non-small cell lung cancer KRAS_G12D EGFR 9 52 Unknown -3.26 -5.25 -1.59 1585.88 1.00 124 9 52 0 TRUE 3.30
non-small cell lung cancer KRAS_G12D EGFR 128 694 White -3.16 -4.55 -2.02 1652.52 1.00 2317 126 692 2 TRUE 5.76
colorectal cancer KRAS_G12D EGFR 246 59 Race:overall -0.99 -5.15 3.81 1404.58 1.00 1636 243 56 3 TRUE 0.20
non-small cell lung cancer KRAS_G12D EGFR 156 1038 Race:overall -3.18 -4.62 -1.85 1630.11 1.00 2791 153 1035 3 TRUE 4.92
colorectal cancer KRAS_G12D ARID1B 215 121 White -1.09 -1.97 -0.32 1293.85 1.00 1430 209 115 6 TRUE 2.05
non-small cell lung cancer KRAS_G12D ARID1B 8 12 Asian -0.69 -3.34 1.05 1257.49 1.00 311 8 12 0 TRUE 0.26
non-small cell lung cancer KRAS_G12D ARID1B 123 82 White -0.44 -1.95 0.62 1084.27 1.00 2718 120 79 3 TRUE 0.30
uterine cancer KRAS_G12D ARID1B 38 89 White 0.78 -0.09 1.57 1383.83 1.00 697 30 81 8 TRUE 1.14
colorectal cancer KRAS_G12D ARID1B 215 121 Race:overall -0.92 -5.03 3.10 1500.79 1.00 1430 209 115 6 TRUE 0.20
non-small cell lung cancer KRAS_G12D ARID1B 131 94 Race:overall -0.54 -2.51 1.17 1060.57 1.00 3029 128 91 3 TRUE 0.25
uterine cancer KRAS_G12D ARID1B 38 89 Race:overall 0.64 -3.80 4.78 1280.81 1.00 697 30 81 8 TRUE 0.13
non-small cell lung cancer KRAS_G12D INSR 123 48 White -1.17 -4.21 0.72 1525.89 1.00 2750 122 47 1 FALSE 0.47
non-small cell lung cancer KRAS_G12D INSR 123 48 Race:overall -1.10 -5.87 3.46 1305.24 1.00 2750 122 47 1 FALSE 0.21
non-small cell lung cancer KRAS_G12D NKX2-1 125 58 White 1.12 0.28 1.87 1158.59 1.00 2749 118 51 7 TRUE 2.09
non-small cell lung cancer KRAS_G12D NKX2-1 125 58 Race:overall 0.94 -4.01 5.26 1419.21 1.00 2749 118 51 7 TRUE 0.18
colorectal cancer KRAS_G12D ARID5B 217 53 White 0.19 -0.64 0.90 1268.84 1.00 1492 209 45 8 FALSE 0.20
uterine cancer KRAS_G12D ARID5B 39 60 White 0.56 -0.52 1.54 1088.38 1.00 716 34 55 5 FALSE 0.55
colorectal cancer KRAS_G12D ARID5B 217 53 Race:overall 0.18 -4.16 4.77 1369.50 1.00 1492 209 45 8 FALSE 0.03
uterine cancer KRAS_G12D ARID5B 39 60 Race:overall 0.49 -3.62 4.46 1371.81 1.00 716 34 55 5 FALSE 0.10
non-small cell lung cancer KRAS_G12D WT1 124 60 White 0.66 -0.40 1.57 1034.48 1.00 2741 119 55 5 TRUE 0.73
non-small cell lung cancer KRAS_G12D WT1 124 60 Race:overall 0.56 -4.01 5.05 1556.80 1.00 2741 119 55 5 TRUE 0.10
non-small cell lung cancer KRAS_G12D MET 8 13 Asian -1.16 -3.90 0.70 1480.52 1.00 331 8 13 0 TRUE 0.49
non-small cell lung cancer KRAS_G12D MET 128 140 White -0.97 -2.29 0.15 634.16 1.00 2756 125 137 3 TRUE 0.87
uterine cancer KRAS_G12D MET 39 51 White 0.22 -1.16 1.54 454.03 1.00 808 36 48 3 TRUE 0.13
non-small cell lung cancer KRAS_G12D MET 136 153 Race:overall -1.04 -3.10 0.66 1347.14 1.00 3087 133 150 3 TRUE 0.53
uterine cancer KRAS_G12D MET 39 51 Race:overall 0.15 -4.72 4.41 1457.08 1.00 808 36 48 3 TRUE 0.02
non-small cell lung cancer KRAS_G12D PMS1 123 44 White -0.15 -1.91 1.11 498.73 1.01 2753 121 42 2 TRUE 0.07
non-small cell lung cancer KRAS_G12D PMS1 123 44 Race:overall -0.15 -4.52 4.47 1217.13 1.00 2753 121 42 2 TRUE 0.03
pancreatic cancer KRAS_G12D MEN1 406 67 White -3.92 -6.73 -2.18 1470.36 1.00 758 405 66 1 TRUE 3.25
pancreatic cancer KRAS_G12D MEN1 406 67 Race:overall -3.17 -7.30 2.69 1393.90 1.00 758 405 66 1 TRUE 0.75
non-small cell lung cancer KRAS_G12D PIK3C3 123 62 White -1.41 -4.34 0.33 1343.58 1.00 2735 122 61 1 FALSE 0.63
non-small cell lung cancer KRAS_G12D PIK3C3 123 62 Race:overall -1.23 -5.99 3.64 1448.43 1.00 2735 122 61 1 FALSE 0.23
colorectal cancer KRAS_G12D BRAF 27 15 Asian -2.25 -3.35 -1.28 1088.69 1.00 137 27 15 0 TRUE 4.62
colorectal cancer KRAS_G12D BRAF 30 14 Black -2.25 -3.40 -1.28 1048.99 1.00 109 30 14 0 TRUE 4.34
colorectal cancer KRAS_G12D BRAF 19 13 Unknown -2.24 -3.43 -1.27 1191.37 1.00 97 19 13 0 TRUE 4.24
colorectal cancer KRAS_G12D BRAF 247 207 White -2.18 -3.19 -1.33 1191.19 1.00 1493 242 202 5 TRUE 5.32
non-small cell lung cancer KRAS_G12D BRAF 128 167 White -0.81 -1.91 0.20 98.85 1.02 2721 124 163 4 TRUE 0.79
colorectal cancer KRAS_G12D BRAF 323 249 Race:overall -2.23 -3.29 -1.34 1121.90 1.00 1836 318 244 5 TRUE 5.00
non-small cell lung cancer KRAS_G12D BRAF 128 167 Race:overall -0.72 -4.67 3.97 1122.30 1.00 2721 124 163 4 TRUE 0.14
colorectal cancer KRAS_G12D B2M 22 16 Asian -0.32 -2.06 0.54 1122.83 1.00 119 22 16 0 FALSE 0.22
colorectal cancer KRAS_G12D B2M 21 11 Unknown 0.21 -0.69 1.38 1236.97 1.00 104 17 7 4 FALSE 0.17
colorectal cancer KRAS_G12D B2M 220 102 White -0.08 -0.68 0.48 1294.76 1.00 1468 208 90 12 FALSE 0.11
colorectal cancer KRAS_G12D B2M 263 129 Race:overall -0.06 -0.97 0.80 1496.99 1.00 1691 247 113 16 FALSE 0.05
colorectal cancer KRAS_G12D TGFBR1 216 33 White 0.59 -0.28 1.42 1327.72 1.00 1502 209 26 7 FALSE 0.74
non-small cell lung cancer KRAS_G12D TGFBR1 123 37 White 0.01 -1.83 1.39 1477.16 1.00 2759 121 35 2 FALSE 0.01
colorectal cancer KRAS_G12D TGFBR1 216 33 Race:overall 0.53 -4.18 4.58 1322.11 1.00 1502 209 26 7 FALSE 0.10
non-small cell lung cancer KRAS_G12D TGFBR1 123 37 Race:overall -0.04 -4.85 4.39 1448.93 1.00 2759 121 35 2 FALSE 0.01
colorectal cancer KRAS_G12D TET2 215 67 White -0.44 -1.40 0.40 1292.03 1.00 1476 209 61 6 TRUE 0.48
non-small cell lung cancer KRAS_G12D TET2 123 66 White -1.39 -4.19 0.26 116.23 1.04 2734 122 65 1 TRUE 0.64
uterine cancer KRAS_G12D TET2 37 55 White 0.05 -1.38 1.25 687.54 1.00 719 34 52 3 TRUE 0.03
colorectal cancer KRAS_G12D TET2 215 67 Race:overall -0.37 -4.67 4.41 1403.44 1.00 1476 209 61 6 TRUE 0.07
non-small cell lung cancer KRAS_G12D TET2 123 66 Race:overall -1.25 -5.50 2.93 936.95 1.01 2734 122 65 1 TRUE 0.27
uterine cancer KRAS_G12D TET2 37 55 Race:overall 0.08 -4.27 4.24 1233.16 1.00 719 34 52 3 TRUE 0.01
colorectal cancer KRAS_G12D PDGFRB 215 38 White -0.34 -1.43 0.70 356.85 1.00 1492 211 34 4 TRUE 0.25
non-small cell lung cancer KRAS_G12D PDGFRB 123 82 White -1.69 -4.24 0.02 1415.97 1.00 2720 122 81 1 TRUE 0.88
colorectal cancer KRAS_G12D PDGFRB 215 38 Race:overall -0.21 -4.39 4.60 1424.90 1.00 1492 211 34 4 TRUE 0.04
non-small cell lung cancer KRAS_G12D PDGFRB 123 82 Race:overall -1.43 -6.03 3.51 1387.03 1.00 2720 122 81 1 TRUE 0.27
colorectal cancer KRAS_G12D CARD11 215 106 White -0.49 -1.27 0.20 1408.98 1.00 1439 206 97 9 FALSE 0.74
non-small cell lung cancer KRAS_G12D CARD11 123 100 White -0.53 -2.05 0.59 1408.71 1.00 2703 120 97 3 FALSE 0.37
uterine cancer KRAS_G12D CARD11 37 47 White -1.16 -3.98 0.50 128.16 1.04 722 36 46 1 FALSE 0.50
colorectal cancer KRAS_G12D CARD11 215 106 Race:overall -0.35 -4.64 4.22 1376.42 1.00 1439 206 97 9 FALSE 0.06
non-small cell lung cancer KRAS_G12D CARD11 123 100 Race:overall -0.33 -4.53 4.35 1387.03 1.00 2703 120 97 3 FALSE 0.06
uterine cancer KRAS_G12D CARD11 37 47 Race:overall -0.98 -5.36 3.26 1235.09 1.00 722 36 46 1 FALSE 0.19
colorectal cancer KRAS_G12D DNMT3A 215 40 White -1.26 -3.46 0.06 284.43 1.00 1491 213 38 2 TRUE 0.86
non-small cell lung cancer KRAS_G12D DNMT3A 123 66 White 0.28 -1.00 1.20 960.93 1.00 2733 119 62 4 TRUE 0.21
colorectal cancer KRAS_G12D DNMT3A 215 40 Race:overall -1.12 -5.31 3.37 809.64 1.00 1491 213 38 2 TRUE 0.22
non-small cell lung cancer KRAS_G12D DNMT3A 123 66 Race:overall 0.22 -4.15 4.53 1444.02 1.00 2733 119 62 4 TRUE 0.04
colorectal cancer KRAS_G12D MSH6 217 83 White -0.18 -0.94 0.47 1540.50 1.00 1465 208 74 9 TRUE 0.22
uterine cancer KRAS_G12D MSH6 39 72 White 0.59 -0.31 1.43 1074.95 1.00 715 33 66 6 TRUE 0.68
colorectal cancer KRAS_G12D MSH6 217 83 Race:overall -0.10 -4.47 4.24 1294.50 1.00 1465 208 74 9 TRUE 0.02
uterine cancer KRAS_G12D MSH6 39 72 Race:overall 0.52 -3.82 4.82 1574.06 1.00 715 33 66 6 TRUE 0.10
non-small cell lung cancer KRAS_G12D MAX 123 46 White 1.19 0.19 2.04 1546.19 1.00 2755 117 40 6 FALSE 2.10
non-small cell lung cancer KRAS_G12D MAX 123 46 Race:overall 1.03 -3.75 5.47 1595.49 1.00 2755 117 40 6 FALSE 0.20
non-small cell lung cancer KRAS_G12D INPP4B 124 111 White 0.68 -0.09 1.37 1318.09 1.00 2700 115 102 9 FALSE 1.20
non-small cell lung cancer KRAS_G12D INPP4B 124 111 Race:overall 0.55 -3.68 4.44 1586.41 1.00 2700 115 102 9 FALSE 0.11
non-small cell lung cancer KRAS_G12D NFE2L2 123 101 White -1.03 -2.79 0.24 1527.12 1.00 2704 121 99 2 FALSE 0.75
non-small cell lung cancer KRAS_G12D NFE2L2 123 101 Race:overall -0.80 -5.21 4.33 1549.49 1.00 2704 121 99 2 FALSE 0.14
uterine cancer KRAS_G12D SPOP 37 39 White -1.39 -4.04 0.58 1282.19 1.00 723 36 38 1 FALSE 0.62
uterine cancer KRAS_G12D SPOP 41 50 Race:overall -1.60 -5.00 0.91 1206.03 1.00 780 40 49 1 FALSE 0.55
colorectal cancer KRAS_G12D SOX9 24 21 Asian 0.39 -0.19 1.08 1533.61 1.00 114 18 15 6 FALSE 0.64
colorectal cancer KRAS_G12D SOX9 27 15 Black 0.26 -0.36 0.90 1378.62 1.00 109 24 12 3 FALSE 0.40
colorectal cancer KRAS_G12D SOX9 217 209 White 0.20 -0.18 0.56 1336.71 1.00 1363 188 180 29 FALSE 0.55
colorectal cancer KRAS_G12D SOX9 268 245 Race:overall 0.28 -0.22 0.86 1223.10 1.00 1586 230 207 38 FALSE 0.53
colorectal cancer KRAS_G12D ETV1 215 44 White -0.19 -1.27 0.72 1427.26 1.00 1490 210 39 5 TRUE 0.15
colorectal cancer KRAS_G12D ETV1 215 44 Race:overall -0.21 -4.92 4.08 1788.05 1.00 1490 210 39 5 TRUE 0.04
colorectal cancer KRAS_G12D ARAF 215 50 White -0.34 -1.22 0.51 687.07 1.00 1486 210 45 5 FALSE 0.35
non-small cell lung cancer KRAS_G12D ARAF 123 52 White -0.39 -2.49 0.97 1004.97 1.00 2749 121 50 2 FALSE 0.19
colorectal cancer KRAS_G12D ARAF 215 50 Race:overall -0.32 -4.28 3.56 1617.58 1.00 1486 210 45 5 FALSE 0.07
non-small cell lung cancer KRAS_G12D ARAF 123 52 Race:overall -0.37 -4.83 4.33 1630.60 1.00 2749 121 50 2 FALSE 0.06
non-small cell lung cancer KRAS_G12D JAK2 128 62 White -0.47 -2.17 0.81 1490.69 1.00 2823 126 60 2 TRUE 0.27
non-small cell lung cancer KRAS_G12D JAK2 128 62 Race:overall -0.38 -4.92 4.15 1689.47 1.00 2823 126 60 2 TRUE 0.07
colorectal cancer KRAS_G12D SMAD2 217 74 White 0.50 -0.11 1.09 905.22 1.00 1474 203 60 14 TRUE 1.00
colorectal cancer KRAS_G12D SMAD2 217 74 Race:overall 0.44 -3.93 4.90 1232.48 1.00 1474 203 60 14 TRUE 0.09
non-small cell lung cancer KRAS_G12D TP63 123 63 White -1.47 -4.26 0.38 1357.73 1.00 2734 122 62 1 FALSE 0.63
non-small cell lung cancer KRAS_G12D TP63 123 63 Race:overall -1.20 -6.10 3.65 1583.36 1.00 2734 122 62 1 FALSE 0.22
colorectal cancer KRAS_G12D JUN 216 41 White -0.08 -1.14 0.84 996.77 1.00 1492 211 36 5 FALSE 0.06
colorectal cancer KRAS_G12D JUN 216 41 Race:overall -0.07 -4.05 3.96 1177.72 1.00 1492 211 36 5 FALSE 0.01
colorectal cancer KRAS_G12D DNMT3B 215 46 White -6.63 -17.23 -1.64 1110.49 1.00 1487 215 46 0 FALSE 0.85
colorectal cancer KRAS_G12D DNMT3B 215 46 Race:overall -4.67 -11.84 2.94 1297.64 1.00 1487 215 46 0 FALSE 0.69
non-small cell lung cancer KRAS_G12D MYOD1 123 46 White -0.21 -1.99 1.12 1448.58 1.00 2754 121 44 2 FALSE 0.10
non-small cell lung cancer KRAS_G12D MYOD1 123 46 Race:overall -0.22 -4.84 4.28 1263.80 1.00 2754 121 44 2 FALSE 0.04
colorectal cancer KRAS_G12D FGFR1 246 37 White 0.20 -0.78 1.03 458.78 1.00 1659 240 31 6 TRUE 0.18
colorectal cancer KRAS_G12D FGFR1 246 37 Race:overall 0.09 -4.79 4.42 1228.51 1.00 1659 240 31 6 TRUE 0.02
colorectal cancer KRAS_G12D MITF 215 42 White 0.30 -0.56 1.11 1478.60 1.00 1490 208 35 7 FALSE 0.31
colorectal cancer KRAS_G12D MITF 215 42 Race:overall 0.28 -4.25 4.59 1551.55 1.00 1490 208 35 7 FALSE 0.05
non-small cell lung cancer KRAS_G12D BTK 123 49 White -1.20 -3.92 0.63 1397.99 1.00 2747 122 48 1 TRUE 0.48
non-small cell lung cancer KRAS_G12D BTK 123 49 Race:overall -0.95 -5.62 4.04 1577.74 1.00 2747 122 48 1 TRUE 0.17
colorectal cancer KRAS_G12D SH2B3 194 41 White -0.04 -1.06 0.78 117.94 1.03 1357 189 36 5 FALSE 0.03
colorectal cancer KRAS_G12D SH2B3 194 41 Race:overall -0.05 -4.25 4.54 1269.73 1.00 1357 189 36 5 FALSE 0.01
colorectal cancer KRAS_G12D GLI1 22 11 Asian 0.59 -0.63 1.87 1388.47 1.00 110 18 7 4 FALSE 0.45
colorectal cancer KRAS_G12D GLI1 194 65 White -0.35 -1.31 0.42 1465.38 1.00 1335 189 60 5 FALSE 0.37
non-small cell lung cancer KRAS_G12D GLI1 111 90 White -0.49 -2.04 0.69 360.03 1.00 2428 108 87 3 FALSE 0.31
colorectal cancer KRAS_G12D GLI1 216 76 Race:overall 0.13 -1.33 1.68 1421.63 1.00 1445 207 67 9 FALSE 0.06
non-small cell lung cancer KRAS_G12D GLI1 111 90 Race:overall -0.44 -4.69 3.70 1365.36 1.00 2428 108 87 3 FALSE 0.08
colorectal cancer KRAS_G12D ZFHX3 21 18 Asian -0.32 -1.88 0.38 1134.77 1.00 105 21 18 0 FALSE 0.21
colorectal cancer KRAS_G12D ZFHX3 19 15 Unknown -0.23 -1.43 0.44 1075.44 1.00 92 18 14 1 FALSE 0.20
colorectal cancer KRAS_G12D ZFHX3 197 183 White 0.03 -0.44 0.47 637.42 1.00 1281 171 157 26 FALSE 0.05
non-small cell lung cancer KRAS_G12D ZFHX3 11 11 Black -0.50 -1.97 1.02 1382.24 1.00 158 10 10 1 FALSE 0.30
non-small cell lung cancer KRAS_G12D ZFHX3 111 136 White -0.67 -1.84 0.32 1183.19 1.00 2381 108 133 3 FALSE 0.63
uterine cancer KRAS_G12D ZFHX3 39 180 White 0.46 -0.19 1.10 1129.28 1.00 569 27 168 12 FALSE 0.78
colorectal cancer KRAS_G12D ZFHX3 237 216 Race:overall -0.17 -1.03 0.43 984.08 1.00 1478 210 189 27 FALSE 0.17
non-small cell lung cancer KRAS_G12D ZFHX3 122 147 Race:overall -0.60 -2.04 0.82 1282.12 1.00 2539 118 143 4 FALSE 0.38
uterine cancer KRAS_G12D ZFHX3 45 206 Race:overall 0.50 -0.42 1.43 1453.02 1.00 699 31 192 14 FALSE 0.55
colorectal cancer KRAS_G12D MST1R 195 60 White -0.27 -1.26 0.56 1019.53 1.00 1346 189 54 6 FALSE 0.26
colorectal cancer KRAS_G12D MST1R 195 60 Race:overall -0.26 -4.57 3.98 1504.17 1.00 1346 189 54 6 FALSE 0.05
colorectal cancer KRAS_G12D MGA 193 99 White -0.86 -1.76 -0.06 1264.97 1.00 1308 187 93 6 FALSE 1.28
non-small cell lung cancer KRAS_G12D MGA 8 15 Asian -1.72 -4.58 0.11 998.84 1.00 273 8 15 0 FALSE 0.82
non-small cell lung cancer KRAS_G12D MGA 111 163 White -1.58 -3.35 -0.30 796.74 1.00 2371 109 161 2 FALSE 1.35
uterine cancer KRAS_G12D MGA 39 93 White -0.15 -1.18 0.76 1022.71 1.00 618 34 88 5 FALSE 0.11
colorectal cancer KRAS_G12D MGA 193 99 Race:overall -0.82 -5.21 3.92 1603.79 1.00 1308 187 93 6 FALSE 0.15
non-small cell lung cancer KRAS_G12D MGA 119 178 Race:overall -1.63 -3.70 0.01 914.41 1.00 2644 117 176 2 FALSE 1.04
uterine cancer KRAS_G12D MGA 42 104 Race:overall -0.30 -2.23 1.06 1190.22 1.00 676 37 99 5 FALSE 0.15
colorectal cancer KRAS_G12D TCF3 193 60 White -0.78 -1.97 0.21 1214.11 1.00 1339 189 56 4 FALSE 0.82
colorectal cancer KRAS_G12D TCF3 193 60 Race:overall -0.64 -4.54 3.57 1287.90 1.00 1339 189 56 4 FALSE 0.12
colorectal cancer KRAS_G12D KMT2B 116 151 White -0.30 -0.89 0.22 723.65 1.01 681 101 136 15 FALSE 0.53
non-small cell lung cancer KRAS_G12D KMT2B 66 59 White -1.44 -4.24 0.32 806.10 1.00 1355 65 58 1 FALSE 0.65
colorectal cancer KRAS_G12D KMT2B 116 151 Race:overall -0.22 -4.41 4.11 1357.90 1.00 681 101 136 15 FALSE 0.04
non-small cell lung cancer KRAS_G12D KMT2B 66 59 Race:overall -1.20 -6.04 3.48 1392.76 1.00 1355 65 58 1 FALSE 0.23
colorectal cancer KRAS_G12D TCF7L2 21 21 Asian 0.14 -0.66 0.71 1068.84 1.00 99 20 20 1 FALSE 0.17
colorectal cancer KRAS_G12D TCF7L2 24 13 Black 0.27 -0.34 0.86 1239.48 1.00 101 21 10 3 FALSE 0.44
colorectal cancer KRAS_G12D TCF7L2 19 21 Unknown 0.44 -0.17 1.23 1354.53 1.00 87 12 14 7 FALSE 0.72
colorectal cancer KRAS_G12D TCF7L2 197 239 White 0.26 -0.13 0.60 661.28 1.01 1203 161 203 36 FALSE 0.80
colorectal cancer KRAS_G12D TCF7L2 261 294 Race:overall 0.28 -0.26 0.75 1111.48 1.00 1490 214 247 47 FALSE 0.57
colorectal cancer KRAS_G12D MSH3 113 76 White -0.85 -1.86 -0.01 1478.89 1.00 708 108 71 5 FALSE 1.10
colorectal cancer KRAS_G12D MSH3 113 76 Race:overall -0.83 -5.19 3.97 1663.72 1.00 708 108 71 5 FALSE 0.16
colorectal cancer KRAS_G12D ANKRD11 196 125 White -0.54 -1.25 0.08 1370.17 1.00 1300 186 115 10 FALSE 0.91
non-small cell lung cancer KRAS_G12D ANKRD11 112 64 White 0.24 -0.88 1.26 609.19 1.01 2451 108 60 4 FALSE 0.17
colorectal cancer KRAS_G12D ANKRD11 196 125 Race:overall -0.45 -4.53 3.79 1456.75 1.00 1300 186 115 10 FALSE 0.09
non-small cell lung cancer KRAS_G12D ANKRD11 112 64 Race:overall 0.18 -4.56 4.80 1477.29 1.00 2451 108 60 4 FALSE 0.03
colorectal cancer KRAS_G12D PGR 195 52 White -0.10 -1.06 0.68 817.90 1.00 1346 189 46 6 FALSE 0.09
non-small cell lung cancer KRAS_G12D PGR 11 13 Black -1.54 -5.37 0.69 1588.88 1.00 155 11 13 0 FALSE 0.49
non-small cell lung cancer KRAS_G12D PGR 111 63 White -0.78 -2.63 0.58 1168.54 1.00 2450 109 61 2 FALSE 0.47
colorectal cancer KRAS_G12D PGR 195 52 Race:overall -0.08 -4.14 4.45 1368.32 1.00 1346 189 46 6 FALSE 0.01
non-small cell lung cancer KRAS_G12D PGR 122 76 Race:overall -1.10 -3.88 1.18 1408.88 1.00 2605 120 74 2 FALSE 0.43
colorectal cancer KRAS_G12D PLCG2 195 64 White 0.36 -0.31 1.00 1236.02 1.01 1341 184 53 11 FALSE 0.55
non-small cell lung cancer KRAS_G12D PLCG2 111 52 White -5.83 -16.68 -0.61 1185.22 1.00 2463 111 52 0 FALSE 0.69
colorectal cancer KRAS_G12D PLCG2 195 64 Race:overall 0.14 -4.42 3.70 1212.23 1.00 1341 184 53 11 FALSE 0.03
non-small cell lung cancer KRAS_G12D PLCG2 111 52 Race:overall -4.09 -11.45 2.75 1476.44 1.00 2463 111 52 0 FALSE 0.61
colorectal cancer KRAS_G12D POLD1 196 95 White -0.34 -1.09 0.32 1207.65 1.00 1326 187 86 9 TRUE 0.45
non-small cell lung cancer KRAS_G12D POLD1 111 49 White 0.19 -1.28 1.32 578.17 1.01 2464 108 46 3 TRUE 0.12
colorectal cancer KRAS_G12D POLD1 196 95 Race:overall -0.25 -4.50 3.85 1330.15 1.00 1326 187 86 9 TRUE 0.05
non-small cell lung cancer KRAS_G12D POLD1 111 49 Race:overall 0.12 -4.30 4.54 1401.62 1.00 2464 108 46 3 TRUE 0.02
colorectal cancer KRAS_G12D INHBA 193 43 White 0.27 -0.62 1.04 1456.06 1.00 1354 186 36 7 FALSE 0.28
non-small cell lung cancer KRAS_G12D INHBA 111 75 White -1.57 -4.22 0.24 1378.14 1.00 2441 110 74 1 FALSE 0.77
colorectal cancer KRAS_G12D INHBA 193 43 Race:overall 0.24 -4.13 4.38 1574.98 1.00 1354 186 36 7 FALSE 0.04
non-small cell lung cancer KRAS_G12D INHBA 111 75 Race:overall -1.19 -5.55 4.10 1057.62 1.00 2441 110 74 1 FALSE 0.22
colorectal cancer KRAS_G12D PREX2 113 78 White -0.31 -1.12 0.43 1455.80 1.00 711 105 70 8 FALSE 0.37
non-small cell lung cancer KRAS_G12D PREX2 7 12 Black -1.04 -4.23 0.69 1168.01 1.00 92 7 12 0 FALSE 0.37
non-small cell lung cancer KRAS_G12D PREX2 66 86 White -0.56 -1.93 0.58 1007.01 1.00 1333 63 83 3 FALSE 0.43
colorectal cancer KRAS_G12D PREX2 113 78 Race:overall -0.29 -4.58 4.14 1478.87 1.00 711 105 70 8 FALSE 0.05
non-small cell lung cancer KRAS_G12D PREX2 73 98 Race:overall -0.77 -3.10 0.92 1274.39 1.00 1425 70 95 3 FALSE 0.35
colorectal cancer KRAS_G12D AMER1 27 12 Black 0.34 -0.63 1.28 1250.37 1.00 112 24 9 3 FALSE 0.34
colorectal cancer KRAS_G12D AMER1 215 135 White 0.29 -0.21 0.74 1323.15 1.00 1424 194 114 21 FALSE 0.67
non-small cell lung cancer KRAS_G12D AMER1 11 16 Black -0.78 -4.21 0.80 825.76 1.00 171 11 16 0 FALSE 0.22
non-small cell lung cancer KRAS_G12D AMER1 123 127 White -0.05 -0.95 0.74 1045.82 1.00 2690 117 121 6 FALSE 0.04
uterine cancer KRAS_G12D AMER1 37 47 White -0.34 -2.08 1.02 1032.07 1.00 731 35 45 2 FALSE 0.17
colorectal cancer KRAS_G12D AMER1 242 147 Race:overall 0.32 -0.67 1.32 1384.82 1.00 1536 218 123 24 FALSE 0.29
non-small cell lung cancer KRAS_G12D AMER1 134 143 Race:overall -0.42 -2.91 1.17 1081.53 1.00 2861 128 137 6 FALSE 0.16
uterine cancer KRAS_G12D AMER1 37 47 Race:overall -0.32 -4.45 3.99 1357.07 1.00 731 35 45 2 FALSE 0.06
colorectal cancer KRAS_G12D HLA-A 193 45 White -1.32 -3.06 -0.01 1100.89 1.00 1354 191 43 2 FALSE 1.00
colorectal cancer KRAS_G12D HLA-A 193 45 Race:overall -1.09 -5.71 3.79 1614.17 1.00 1354 191 43 2 FALSE 0.21
colorectal cancer KRAS_G12D EPHA7 194 69 White 0.02 -0.79 0.75 442.94 1.01 1338 185 60 9 FALSE 0.02
non-small cell lung cancer KRAS_G12D EPHA7 112 110 White -0.03 -1.08 0.78 1353.17 1.00 2409 107 105 5 FALSE 0.02
colorectal cancer KRAS_G12D EPHA7 194 69 Race:overall -0.02 -4.34 4.07 1243.39 1.00 1338 185 60 9 FALSE 0.00
non-small cell lung cancer KRAS_G12D EPHA7 112 110 Race:overall -0.04 -4.20 4.49 1381.38 1.00 2409 107 105 5 FALSE 0.01
colorectal cancer KRAS_G12D NCOA3 193 45 White -0.48 -1.68 0.48 1493.74 1.00 1352 189 41 4 TRUE 0.41
colorectal cancer KRAS_G12D NCOA3 193 45 Race:overall -0.42 -4.75 3.88 1421.31 1.00 1352 189 41 4 TRUE 0.08
non-small cell lung cancer KRAS_G12D DROSHA 66 42 White -5.52 -15.34 -0.63 657.56 1.01 1368 66 42 0 FALSE 0.67
non-small cell lung cancer KRAS_G12D DROSHA 66 42 Race:overall -3.92 -11.61 2.88 1322.02 1.00 1368 66 42 0 FALSE 0.58
colorectal cancer KRAS_G12D SLX4 112 47 White -0.08 -1.09 0.79 1000.89 1.00 733 106 41 6 FALSE 0.06
colorectal cancer KRAS_G12D SLX4 112 47 Race:overall -0.05 -4.56 4.28 1596.38 1.00 733 106 41 6 FALSE 0.01
colorectal cancer KRAS_G12D INPPL1 112 61 White -0.85 -2.08 0.11 1507.56 1.00 726 108 57 4 FALSE 0.93
colorectal cancer KRAS_G12D INPPL1 112 61 Race:overall -0.79 -4.99 3.92 1437.70 1.00 726 108 57 4 FALSE 0.16
colorectal cancer KRAS_G12V SPEN 17 11 Black -2.18 -4.88 -0.60 1006.81 1.00 121 17 11 0 FALSE 1.31
colorectal cancer KRAS_G12V SPEN 147 121 White -2.01 -3.74 -0.74 950.07 1.00 1507 145 119 2 FALSE 2.00
non-small cell lung cancer KRAS_G12V SPEN 147 101 White -0.09 -1.16 0.70 881.63 1.00 2704 142 96 5 FALSE 0.07
uterine cancer KRAS_G12V SPEN 44 91 White -1.29 -3.10 0.08 1407.17 1.00 698 43 90 1 FALSE 0.94
colorectal cancer KRAS_G12V SPEN 164 132 Race:overall -2.10 -4.21 -0.63 1059.57 1.00 1628 162 130 2 FALSE 1.45
non-small cell lung cancer KRAS_G12V SPEN 147 101 Race:overall -0.08 -4.92 4.59 1517.27 1.00 2704 142 96 5 FALSE 0.01
uterine cancer KRAS_G12V SPEN 49 107 Race:overall -0.71 -2.84 1.32 1273.00 1.00 757 46 104 3 FALSE 0.30
colorectal cancer KRAS_G12V KMT2C 13 14 Asian -1.24 -2.29 -0.34 1308.94 1.00 128 13 14 0 FALSE 2.00
colorectal cancer KRAS_G12V KMT2C 17 12 Black -1.24 -2.33 -0.35 1285.68 1.00 123 17 12 0 FALSE 1.89
colorectal cancer KRAS_G12V KMT2C 9 11 Unknown -1.24 -2.30 -0.34 1376.27 1.00 112 9 11 0 FALSE 1.96
colorectal cancer KRAS_G12V KMT2C 148 157 White -1.19 -2.13 -0.42 1194.53 1.00 1485 142 151 6 FALSE 2.23
non-small cell lung cancer KRAS_G12V KMT2C 9 11 Black 0.56 -0.90 2.08 1427.90 1.00 175 8 10 1 FALSE 0.34
non-small cell lung cancer KRAS_G12V KMT2C 148 185 White 0.32 -0.30 0.88 1417.93 1.00 2612 136 173 12 FALSE 0.53
uterine cancer KRAS_G12V KMT2C 44 117 White -0.46 -1.56 0.47 851.79 1.00 687 39 112 5 FALSE 0.43
colorectal cancer KRAS_G12V KMT2C 187 194 Race:overall -1.23 -2.26 -0.40 1306.95 1.00 1848 181 188 6 FALSE 2.11
non-small cell lung cancer KRAS_G12V KMT2C 160 210 Race:overall 0.54 -0.66 1.90 1423.10 1.00 3100 146 196 14 FALSE 0.40
uterine cancer KRAS_G12V KMT2C 49 131 Race:overall -0.63 -2.55 0.76 1278.60 1.00 745 44 126 5 FALSE 0.34
cancer of unknown primary KRAS_G12V TP53 38 334 White 0.22 -0.36 0.83 856.69 1.00 292 18 314 20 TRUE 0.33
colorectal cancer KRAS_G12V TP53 16 124 Asian -1.03 -1.78 -0.48 1386.47 1.00 52 12 120 4 TRUE 2.64
colorectal cancer KRAS_G12V TP53 18 117 Black -0.69 -1.24 -0.14 1359.31 1.00 38 6 105 12 TRUE 1.87
colorectal cancer KRAS_G12V TP53 7 26 Race:Other -0.86 -1.63 -0.25 1637.47 1.00 22 5 24 2 TRUE 1.94
colorectal cancer KRAS_G12V TP53 9 96 Unknown -0.93 -1.67 -0.38 1492.79 1.00 29 5 92 4 TRUE 2.44
colorectal cancer KRAS_G12V TP53 171 1350 White -0.74 -1.02 -0.44 1489.01 1.00 602 82 1261 89 TRUE 5.92
non-small cell lung cancer KRAS_G12V TP53 9 128 Black -0.70 -1.48 0.04 1314.03 1.00 75 5 124 4 TRUE 1.17
non-small cell lung cancer KRAS_G12V TP53 9 98 Unknown -0.72 -1.56 0.04 1277.83 1.00 84 6 95 3 TRUE 1.16
non-small cell lung cancer KRAS_G12V TP53 154 1617 White -0.66 -0.97 -0.34 1316.32 1.00 1410 98 1561 56 TRUE 4.46
pancreatic cancer KRAS_G12V TP53 25 44 Asian 0.85 0.48 1.29 1150.21 1.00 30 6 25 19 TRUE 4.88
pancreatic cancer KRAS_G12V TP53 15 39 Black 0.80 0.38 1.16 1242.66 1.00 12 4 28 11 TRUE 4.31
pancreatic cancer KRAS_G12V TP53 19 50 Unknown 0.79 0.38 1.15 1060.89 1.00 27 5 36 14 TRUE 4.41
pancreatic cancer KRAS_G12V TP53 323 792 White 0.81 0.55 1.07 842.74 1.00 411 81 550 242 TRUE 9.46
uterine cancer KRAS_G12V TP53 6 36 Asian -1.30 -2.38 -0.30 1450.92 1.00 49 5 35 1 TRUE 1.86
uterine cancer KRAS_G12V TP53 6 33 Unknown -1.17 -2.18 -0.09 1562.61 1.00 31 4 31 2 TRUE 1.60
uterine cancer KRAS_G12V TP53 51 388 White -1.35 -2.03 -0.70 1022.68 1.00 486 43 380 8 TRUE 4.03
cancer of unknown primary KRAS_G12V TP53 45 409 Race:overall 0.28 -0.43 1.05 1040.43 1.00 359 19 383 26 TRUE 0.34
colorectal cancer KRAS_G12V TP53 221 1713 Race:overall -0.85 -1.37 -0.40 1625.27 1.00 743 110 1602 111 TRUE 3.36
non-small cell lung cancer KRAS_G12V TP53 178 2050 Race:overall -0.74 -1.34 -0.20 1260.55 1.00 1778 113 1985 65 TRUE 1.93
pancreatic cancer KRAS_G12V TP53 386 944 Race:overall 0.80 0.47 1.12 1074.96 1.00 490 97 655 289 TRUE 6.13
uterine cancer KRAS_G12V TP53 65 541 Race:overall -1.29 -2.18 -0.43 1454.72 1.00 621 53 529 12 TRUE 2.51
colorectal cancer KRAS_G12V ATRX 147 96 White -0.61 -1.59 0.26 1387.59 1.00 1517 142 91 5 TRUE 0.70
non-small cell lung cancer KRAS_G12V ATRX 9 11 Black -0.20 -2.40 0.82 918.17 1.00 176 9 11 0 TRUE 0.09
non-small cell lung cancer KRAS_G12V ATRX 148 186 White 0.09 -0.59 0.70 1338.74 1.00 2619 137 175 11 TRUE 0.11
uterine cancer KRAS_G12V ATRX 44 136 White -2.74 -5.05 -0.98 1290.95 1.00 678 43 135 1 TRUE 1.97
colorectal cancer KRAS_G12V ATRX 147 96 Race:overall -0.52 -5.12 4.00 1475.35 1.00 1517 142 91 5 TRUE 0.10
non-small cell lung cancer KRAS_G12V ATRX 157 197 Race:overall -0.04 -1.54 0.92 1219.48 1.00 2795 146 186 11 TRUE 0.02
uterine cancer KRAS_G12V ATRX 55 175 Race:overall -2.77 -5.19 -0.97 1267.06 1.00 879 54 174 1 TRUE 1.91
colorectal cancer KRAS_G12V ATR 13 11 Asian -1.49 -3.69 -0.02 1155.33 1.00 129 13 11 0 FALSE 0.91
colorectal cancer KRAS_G12V ATR 147 88 White -1.28 -2.60 -0.19 462.17 1.00 1531 144 85 3 FALSE 1.34
non-small cell lung cancer KRAS_G12V ATR 147 103 White -1.24 -3.04 0.05 1360.12 1.00 2674 145 101 2 FALSE 0.92
uterine cancer KRAS_G12V ATR 44 81 White -6.38 -13.60 -1.24 175.90 1.04 707 44 81 0 FALSE 1.22
colorectal cancer KRAS_G12V ATR 160 99 Race:overall -1.37 -3.21 0.06 796.64 1.00 1660 157 96 3 FALSE 0.97
non-small cell lung cancer KRAS_G12V ATR 147 103 Race:overall -0.98 -5.34 4.24 1447.10 1.00 2674 145 101 2 FALSE 0.18
uterine cancer KRAS_G12V ATR 44 81 Race:overall -5.21 -11.86 2.21 35.17 1.09 707 44 81 0 FALSE 0.86
colorectal cancer KRAS_G12V PDGFRA 166 44 White 0.24 -0.74 1.09 246.03 1.01 1727 161 39 5 TRUE 0.23
non-small cell lung cancer KRAS_G12V PDGFRA 9 12 Unknown -0.48 -2.56 1.43 1462.77 1.00 160 8 11 1 TRUE 0.20
non-small cell lung cancer KRAS_G12V PDGFRA 152 112 White -1.05 -2.50 0.03 1537.03 1.00 2753 150 110 2 TRUE 0.96
colorectal cancer KRAS_G12V PDGFRA 166 44 Race:overall 0.16 -4.11 4.10 1470.46 1.00 1727 161 39 5 TRUE 0.03
non-small cell lung cancer KRAS_G12V PDGFRA 164 137 Race:overall -0.79 -2.62 0.90 1561.95 1.00 3247 161 134 3 TRUE 0.40
colorectal cancer KRAS_G12V FBXW7 17 34 Asian -0.57 -1.31 0.06 1079.82 1.00 137 15 32 2 TRUE 1.00
colorectal cancer KRAS_G12V FBXW7 17 20 Black -0.65 -1.44 -0.04 867.04 1.00 117 17 20 0 TRUE 1.13
colorectal cancer KRAS_G12V FBXW7 9 26 Unknown -0.59 -1.38 0.08 1423.94 1.00 96 8 25 1 TRUE 0.97
colorectal cancer KRAS_G12V FBXW7 167 254 White -0.51 -1.02 -0.06 1073.13 1.00 1559 151 238 16 TRUE 1.46
non-small cell lung cancer KRAS_G12V FBXW7 152 64 White 0.11 -1.12 1.10 1148.07 1.00 2803 148 60 4 TRUE 0.07
uterine cancer KRAS_G12V FBXW7 50 115 White -0.71 -1.86 0.28 1479.80 1.00 729 46 111 4 TRUE 0.71
colorectal cancer KRAS_G12V FBXW7 210 334 Race:overall -0.58 -1.22 -0.06 1041.49 1.00 1909 191 315 19 TRUE 1.29
non-small cell lung cancer KRAS_G12V FBXW7 152 64 Race:overall 0.17 -4.25 4.78 1354.47 1.00 2803 148 60 4 TRUE 0.03
uterine cancer KRAS_G12V FBXW7 51 130 Race:overall -0.83 -3.40 1.38 1270.65 1.00 822 47 126 4 TRUE 0.32
colorectal cancer KRAS_G12V MAP3K1 147 70 White -0.22 -1.16 0.58 1229.73 1.00 1536 142 65 5 FALSE 0.21
non-small cell lung cancer KRAS_G12V MAP3K1 148 56 White -0.63 -2.41 0.68 1294.41 1.00 2717 146 54 2 FALSE 0.36
uterine cancer KRAS_G12V MAP3K1 44 57 White -5.81 -15.07 -0.99 1080.08 1.00 705 44 57 0 FALSE 0.94
colorectal cancer KRAS_G12V MAP3K1 147 70 Race:overall -0.13 -4.16 4.12 1567.59 1.00 1536 142 65 5 FALSE 0.02
non-small cell lung cancer KRAS_G12V MAP3K1 148 56 Race:overall -0.45 -4.45 3.95 1601.88 1.00 2717 146 54 2 FALSE 0.08
uterine cancer KRAS_G12V MAP3K1 44 57 Race:overall -4.33 -11.67 2.45 1293.61 1.00 705 44 57 0 FALSE 0.65
colorectal cancer KRAS_G12V NSD1 148 71 White -0.53 -1.67 0.42 1330.70 1.00 1537 144 67 4 FALSE 0.50
non-small cell lung cancer KRAS_G12V NSD1 147 67 White 0.36 -0.65 1.22 805.51 1.00 2709 142 62 5 FALSE 0.35
uterine cancer KRAS_G12V NSD1 6 11 Unknown 0.28 -1.11 1.89 485.11 1.01 51 4 9 2 FALSE 0.15
uterine cancer KRAS_G12V NSD1 44 95 White -0.18 -1.19 0.74 1077.15 1.00 694 40 91 4 FALSE 0.14
colorectal cancer KRAS_G12V NSD1 148 71 Race:overall -0.50 -4.59 3.74 1484.92 1.00 1537 144 67 4 FALSE 0.10
non-small cell lung cancer KRAS_G12V NSD1 147 67 Race:overall 0.34 -4.10 4.27 1469.76 1.00 2709 142 62 5 FALSE 0.06
uterine cancer KRAS_G12V NSD1 50 106 Race:overall 0.04 -1.39 1.55 703.11 1.01 745 44 100 6 FALSE 0.02
colorectal cancer KRAS_G12V FLT4 148 115 White -0.83 -1.88 0.00 1341.77 1.00 1497 143 110 5 TRUE 1.06
non-small cell lung cancer KRAS_G12V FLT4 147 84 White -0.53 -1.89 0.60 640.64 1.00 2692 144 81 3 TRUE 0.38
uterine cancer KRAS_G12V FLT4 44 34 White -5.20 -14.54 -0.27 731.87 1.00 724 44 34 0 TRUE 0.79
colorectal cancer KRAS_G12V FLT4 148 115 Race:overall -0.67 -4.82 3.66 1515.39 1.00 1497 143 110 5 TRUE 0.13
non-small cell lung cancer KRAS_G12V FLT4 147 84 Race:overall -0.39 -4.65 4.59 1480.55 1.00 2692 144 81 3 TRUE 0.07
uterine cancer KRAS_G12V FLT4 44 34 Race:overall -3.89 -10.98 2.71 1184.68 1.00 724 44 34 0 TRUE 0.59
colorectal cancer KRAS_G12V PTPRD 147 85 White -1.59 -3.34 -0.33 1321.85 1.00 1526 145 83 2 FALSE 1.38
non-small cell lung cancer KRAS_G12V PTPRD 10 27 Black 0.52 -0.61 1.68 1483.26 1.00 162 7 24 3 FALSE 0.42
non-small cell lung cancer KRAS_G12V PTPRD 8 21 Unknown 0.15 -1.14 1.31 1259.74 1.00 154 7 20 1 FALSE 0.09
non-small cell lung cancer KRAS_G12V PTPRD 148 320 White 0.04 -0.51 0.52 1550.15 1.00 2514 132 304 16 FALSE 0.06
uterine cancer KRAS_G12V PTPRD 44 82 White -1.04 -2.78 0.23 697.64 1.00 709 42 80 2 FALSE 0.71
colorectal cancer KRAS_G12V PTPRD 147 85 Race:overall -1.29 -5.44 3.48 1512.77 1.00 1526 145 83 2 FALSE 0.25
non-small cell lung cancer KRAS_G12V PTPRD 169 386 Race:overall 0.18 -0.81 1.09 1451.97 1.00 3139 149 366 20 FALSE 0.14
uterine cancer KRAS_G12V PTPRD 44 82 Race:overall -0.84 -4.73 3.23 1376.21 1.00 709 42 80 2 FALSE 0.17
colorectal cancer KRAS_G12V RET 166 58 White -1.22 -2.86 0.04 1377.77 1.00 1711 164 56 2 TRUE 0.94
non-small cell lung cancer KRAS_G12V RET 152 81 White 0.34 -0.61 1.16 1191.69 1.00 2784 146 75 6 TRUE 0.34
colorectal cancer KRAS_G12V RET 166 58 Race:overall -0.97 -5.38 4.23 1469.25 1.00 1711 164 56 2 TRUE 0.18
non-small cell lung cancer KRAS_G12V RET 152 81 Race:overall 0.38 -4.00 4.95 1539.54 1.00 2784 146 75 6 TRUE 0.07
colorectal cancer KRAS_G12V KDM5A 147 74 White -1.50 -3.53 -0.11 606.24 1.00 1536 145 72 2 FALSE 1.09
non-small cell lung cancer KRAS_G12V KDM5A 147 62 White -0.20 -1.50 0.84 1115.12 1.00 2715 144 59 3 FALSE 0.13
uterine cancer KRAS_G12V KDM5A 44 49 White -1.51 -4.43 0.33 1161.81 1.00 718 43 48 1 FALSE 0.67
colorectal cancer KRAS_G12V KDM5A 147 74 Race:overall -1.26 -5.61 3.48 1330.86 1.00 1536 145 72 2 FALSE 0.24
non-small cell lung cancer KRAS_G12V KDM5A 147 62 Race:overall -0.15 -4.33 4.44 1487.24 1.00 2715 144 59 3 FALSE 0.02
uterine cancer KRAS_G12V KDM5A 44 49 Race:overall -1.28 -6.12 3.23 1476.07 1.00 718 43 48 1 FALSE 0.23
colorectal cancer KRAS_G12V PIK3C2G 147 65 White -0.20 -1.30 0.65 1585.53 1.00 1540 142 60 5 FALSE 0.17
non-small cell lung cancer KRAS_G12V PIK3C2G 147 113 White -1.37 -3.21 -0.08 733.38 1.00 2667 145 111 2 FALSE 1.01
colorectal cancer KRAS_G12V PIK3C2G 147 65 Race:overall -0.18 -4.58 4.35 1573.04 1.00 1540 142 60 5 FALSE 0.03
non-small cell lung cancer KRAS_G12V PIK3C2G 147 113 Race:overall -1.20 -5.67 3.44 1259.01 1.00 2667 145 111 2 FALSE 0.24
non-small cell lung cancer KRAS_G12V TSHR 147 58 White -0.16 -1.68 0.96 874.90 1.00 2718 144 55 3 TRUE 0.09
non-small cell lung cancer KRAS_G12V TSHR 147 58 Race:overall -0.12 -4.46 4.05 1349.49 1.00 2718 144 55 3 TRUE 0.02
colorectal cancer KRAS_G12V CREBBP 13 13 Asian -0.99 -1.92 -0.17 1331.71 1.00 129 13 13 0 TRUE 1.56
colorectal cancer KRAS_G12V CREBBP 17 11 Black -0.96 -1.94 -0.13 1313.91 1.00 123 16 10 1 TRUE 1.44
colorectal cancer KRAS_G12V CREBBP 9 11 Unknown -0.98 -1.93 -0.16 1375.57 1.00 111 9 11 0 TRUE 1.51
colorectal cancer KRAS_G12V CREBBP 147 148 White -0.97 -1.79 -0.26 1225.01 1.00 1485 141 142 6 TRUE 1.87
non-small cell lung cancer KRAS_G12V CREBBP 147 122 White 0.04 -0.79 0.86 112.03 1.04 2665 140 115 7 TRUE 0.04
uterine cancer KRAS_G12V CREBBP 45 78 White -0.19 -1.36 0.75 1459.17 1.00 698 41 74 4 TRUE 0.14
colorectal cancer KRAS_G12V CREBBP 186 183 Race:overall -0.97 -1.88 -0.20 1331.21 1.00 1848 179 176 7 TRUE 1.67
non-small cell lung cancer KRAS_G12V CREBBP 147 122 Race:overall 0.07 -4.36 4.77 1286.80 1.00 2665 140 115 7 TRUE 0.01
uterine cancer KRAS_G12V CREBBP 45 78 Race:overall -0.19 -4.75 4.15 1533.19 1.00 698 41 74 4 TRUE 0.03
non-small cell lung cancer KRAS_G12V BRIP1 147 53 White -1.46 -4.25 0.32 1200.18 1.00 2719 146 52 1 TRUE 0.69
non-small cell lung cancer KRAS_G12V BRIP1 147 53 Race:overall -1.27 -5.78 3.33 1370.41 1.00 2719 146 52 1 TRUE 0.24
colorectal cancer KRAS_G12V AXIN2 147 87 White -1.15 -2.62 -0.07 1291.29 1.00 1522 144 84 3 TRUE 1.13
non-small cell lung cancer KRAS_G12V AXIN2 147 52 White 0.58 -0.51 1.53 726.00 1.01 2723 142 47 5 TRUE 0.61
uterine cancer KRAS_G12V AXIN2 44 46 White -1.41 -4.13 0.51 1138.51 1.00 714 43 45 1 TRUE 0.64
colorectal cancer KRAS_G12V AXIN2 147 87 Race:overall -0.98 -5.45 3.73 1395.28 1.00 1522 144 84 3 TRUE 0.20
non-small cell lung cancer KRAS_G12V AXIN2 147 52 Race:overall 0.51 -4.16 4.82 1568.84 1.00 2723 142 47 5 TRUE 0.10
uterine cancer KRAS_G12V AXIN2 44 46 Race:overall -1.16 -5.36 3.34 1206.94 1.00 714 43 45 1 TRUE 0.24
colorectal cancer KRAS_G12V DOT1L 147 67 White -1.38 -3.12 -0.12 1184.93 1.00 1540 145 65 2 FALSE 1.10
non-small cell lung cancer KRAS_G12V DOT1L 147 88 White 0.03 -1.12 0.93 1385.49 1.00 2690 142 83 5 FALSE 0.02
colorectal cancer KRAS_G12V DOT1L 147 67 Race:overall -1.16 -5.56 3.65 1512.67 1.00 1540 145 65 2 FALSE 0.23
non-small cell lung cancer KRAS_G12V DOT1L 147 88 Race:overall 0.00 -4.77 4.05 1506.62 1.00 2690 142 83 5 FALSE 0.00
colorectal cancer KRAS_G12V PTPRS 13 21 Asian -0.57 -1.27 0.13 1308.19 1.00 120 11 19 2 FALSE 0.94
colorectal cancer KRAS_G12V PTPRS 17 15 Black -0.62 -1.37 0.07 1157.37 1.00 121 17 15 0 FALSE 1.02
colorectal cancer KRAS_G12V PTPRS 9 15 Unknown -0.59 -1.30 0.08 1472.70 1.00 108 8 14 1 FALSE 0.95
colorectal cancer KRAS_G12V PTPRS 147 200 White -0.60 -1.19 -0.02 1206.34 1.00 1443 137 190 10 FALSE 1.31
non-small cell lung cancer KRAS_G12V PTPRS 147 69 White 0.54 -0.45 1.37 1445.46 1.00 2713 141 63 6 FALSE 0.62
uterine cancer KRAS_G12V PTPRS 45 68 White -0.41 -1.82 0.69 1099.22 1.00 701 42 65 3 FALSE 0.27
colorectal cancer KRAS_G12V PTPRS 186 251 Race:overall -0.59 -1.26 0.03 1258.42 1.00 1792 173 238 13 FALSE 1.14
non-small cell lung cancer KRAS_G12V PTPRS 147 69 Race:overall 0.39 -4.08 5.06 1598.25 1.00 2713 141 63 6 FALSE 0.07
uterine cancer KRAS_G12V PTPRS 45 68 Race:overall -0.40 -4.52 3.98 1538.93 1.00 701 42 65 3 FALSE 0.08
colorectal cancer KRAS_G12V SMARCA4 17 19 Black -1.70 -3.26 -0.34 1176.39 1.00 120 16 18 1 FALSE 1.65
colorectal cancer KRAS_G12V SMARCA4 9 14 Unknown -1.82 -3.44 -0.47 1340.50 1.00 109 9 14 0 FALSE 1.74
colorectal cancer KRAS_G12V SMARCA4 147 126 White -1.81 -3.28 -0.76 1020.07 1.00 1494 145 124 2 FALSE 2.41
non-small cell lung cancer KRAS_G12V SMARCA4 9 24 Black 0.26 -1.15 1.52 1485.75 1.00 165 8 23 1 FALSE 0.15
non-small cell lung cancer KRAS_G12V SMARCA4 8 11 Unknown 0.82 -0.54 2.20 1512.83 1.00 158 6 9 2 FALSE 0.62
non-small cell lung cancer KRAS_G12V SMARCA4 147 264 White 0.37 -0.16 0.83 1486.99 1.00 2541 129 246 18 FALSE 0.82
uterine cancer KRAS_G12V SMARCA4 44 80 White -1.06 -2.94 0.29 1221.30 1.00 699 42 78 2 FALSE 0.72
colorectal cancer KRAS_G12V SMARCA4 173 159 Race:overall -1.77 -3.28 -0.54 1227.93 1.00 1723 170 156 3 FALSE 1.98
non-small cell lung cancer KRAS_G12V SMARCA4 167 310 Race:overall 0.40 -0.76 1.44 1528.45 1.00 3180 146 289 21 FALSE 0.32
uterine cancer KRAS_G12V SMARCA4 44 80 Race:overall -0.92 -5.21 3.50 1328.02 1.00 699 42 78 2 FALSE 0.17
colorectal cancer KRAS_G12V PTPRT 9 12 Unknown -0.68 -3.10 0.43 1240.39 1.00 111 9 12 0 FALSE 0.30
colorectal cancer KRAS_G12V PTPRT 147 150 White -0.38 -1.12 0.24 1450.95 1.00 1469 137 140 10 FALSE 0.55
non-small cell lung cancer KRAS_G12V PTPRT 9 21 Black -0.86 -3.19 0.62 1290.09 1.00 167 9 21 0 FALSE 0.43
non-small cell lung cancer KRAS_G12V PTPRT 8 16 Unknown -0.82 -3.09 0.77 1180.51 1.00 153 8 16 0 FALSE 0.39
non-small cell lung cancer KRAS_G12V PTPRT 149 299 White -0.02 -0.60 0.50 1395.92 1.00 2540 133 283 16 FALSE 0.02
uterine cancer KRAS_G12V PTPRT 44 69 White -1.85 -4.59 -0.02 1592.74 1.00 703 43 68 1 FALSE 0.93
colorectal cancer KRAS_G12V PTPRT 156 162 Race:overall -0.52 -2.11 0.55 1420.74 1.00 1580 146 152 10 FALSE 0.34
non-small cell lung cancer KRAS_G12V PTPRT 169 348 Race:overall -0.57 -2.22 0.66 1350.37 1.00 3175 153 332 16 FALSE 0.37
uterine cancer KRAS_G12V PTPRT 44 69 Race:overall -1.61 -6.03 3.19 1532.62 1.00 703 43 68 1 FALSE 0.33
colorectal cancer KRAS_G12V HGF 147 39 White -1.75 -4.42 0.05 1072.77 1.00 1559 146 38 1 FALSE 0.86
non-small cell lung cancer KRAS_G12V HGF 9 17 Black -1.01 -3.36 0.48 1353.11 1.00 169 9 17 0 FALSE 0.48
non-small cell lung cancer KRAS_G12V HGF 147 156 White -0.68 -1.67 0.20 1416.73 1.00 2631 142 151 5 FALSE 0.78
colorectal cancer KRAS_G12V HGF 147 39 Race:overall -1.40 -5.92 3.61 1254.18 1.00 1559 146 38 1 FALSE 0.28
non-small cell lung cancer KRAS_G12V HGF 156 173 Race:overall -0.82 -2.82 0.51 1452.41 1.00 2800 151 168 5 FALSE 0.51
colorectal cancer KRAS_G12V BLM 147 50 White -1.98 -4.73 -0.16 1510.52 1.00 1553 146 49 1 TRUE 1.01
colorectal cancer KRAS_G12V BLM 147 50 Race:overall -1.72 -6.47 3.08 1489.59 1.00 1553 146 49 1 TRUE 0.35
colorectal cancer KRAS_G12V PIK3CA 16 33 Asian 0.46 0.01 0.94 844.54 1.00 140 11 28 5 TRUE 1.30
colorectal cancer KRAS_G12V PIK3CA 17 32 Black 0.47 0.04 0.96 850.71 1.00 112 11 26 6 TRUE 1.44
colorectal cancer KRAS_G12V PIK3CA 9 30 Unknown 0.46 0.03 0.97 1050.73 1.00 98 5 26 4 TRUE 1.33
colorectal cancer KRAS_G12V PIK3CA 170 403 White 0.40 0.07 0.71 740.67 1.00 1444 127 360 43 TRUE 1.79
non-small cell lung cancer KRAS_G12V PIK3CA 9 13 Black -0.89 -3.42 0.84 1568.34 1.00 178 9 13 0 TRUE 0.39
non-small cell lung cancer KRAS_G12V PIK3CA 152 189 White -0.35 -1.17 0.33 1477.02 1.00 2684 144 181 8 TRUE 0.43
uterine cancer KRAS_G12V PIK3CA 7 40 Asian -0.11 -0.96 0.60 849.21 1.00 53 5 38 2 TRUE 0.11
uterine cancer KRAS_G12V PIK3CA 7 32 Unknown -0.10 -0.98 0.62 1002.85 1.00 39 5 30 2 TRUE 0.10
uterine cancer KRAS_G12V PIK3CA 57 430 White -0.01 -0.50 0.48 808.36 1.00 517 31 404 26 TRUE 0.01
colorectal cancer KRAS_G12V PIK3CA 212 498 Race:overall 0.45 0.06 0.85 792.07 1.00 1794 154 440 58 TRUE 1.64
non-small cell lung cancer KRAS_G12V PIK3CA 164 233 Race:overall -0.70 -2.64 0.75 1407.19 1.00 3177 156 225 8 TRUE 0.40
uterine cancer KRAS_G12V PIK3CA 73 557 Race:overall -0.09 -0.77 0.50 811.71 1.00 697 42 526 31 TRUE 0.11
non-small cell lung cancer KRAS_G12V GATA3 147 57 White -0.62 -2.49 0.69 1721.15 1.00 2719 145 55 2 FALSE 0.37
non-small cell lung cancer KRAS_G12V GATA3 147 57 Race:overall -0.49 -4.65 4.35 1537.06 1.00 2719 145 55 2 FALSE 0.09
colorectal cancer KRAS_G12V ESR1 147 61 White -1.20 -2.95 0.05 859.24 1.00 1537 145 59 2 TRUE 0.90
non-small cell lung cancer KRAS_G12V ESR1 147 45 White -1.29 -4.01 0.50 1322.00 1.00 2729 146 44 1 TRUE 0.56
colorectal cancer KRAS_G12V ESR1 147 61 Race:overall -1.02 -5.09 3.69 1393.55 1.00 1537 145 59 2 TRUE 0.21
non-small cell lung cancer KRAS_G12V ESR1 147 45 Race:overall -1.05 -5.57 3.86 1463.59 1.00 2729 146 44 1 TRUE 0.19
colorectal cancer KRAS_G12V ALK 166 95 White -2.62 -5.27 -0.86 1220.12 1.00 1686 165 94 1 TRUE 1.71
non-small cell lung cancer KRAS_G12V ALK 152 141 White 0.06 -0.71 0.76 1547.11 1.00 2732 144 133 8 TRUE 0.06
uterine cancer KRAS_G12V ALK 50 45 White -5.99 -14.20 -0.86 630.19 1.01 791 50 45 0 TRUE 0.94
colorectal cancer KRAS_G12V ALK 166 95 Race:overall -2.19 -6.69 2.74 1406.68 1.00 1686 165 94 1 TRUE 0.48
non-small cell lung cancer KRAS_G12V ALK 155 154 Race:overall -0.24 -3.04 2.23 1459.76 1.00 3066 147 146 8 TRUE 0.07
uterine cancer KRAS_G12V ALK 50 45 Race:overall -4.71 -11.93 2.39 360.72 1.01 791 50 45 0 TRUE 0.69
colorectal cancer KRAS_G12V RNF43 13 21 Asian -2.04 -3.28 -0.97 528.88 1.02 123 13 21 0 TRUE 3.08
colorectal cancer KRAS_G12V RNF43 17 15 Black -2.03 -3.27 -0.98 494.62 1.02 120 17 15 0 TRUE 3.18
colorectal cancer KRAS_G12V RNF43 147 217 White -1.98 -3.01 -1.00 171.35 1.03 1436 143 213 4 TRUE 3.91
pancreatic cancer KRAS_G12V RNF43 314 66 White 0.32 -0.20 0.84 1593.33 1.00 873 293 45 21 TRUE 0.63
uterine cancer KRAS_G12V RNF43 45 77 White -0.55 -1.98 0.59 1376.67 1.00 690 42 74 3 TRUE 0.39
colorectal cancer KRAS_G12V RNF43 177 253 Race:overall -2.02 -3.14 -1.00 347.18 1.03 1679 173 249 4 TRUE 3.56
pancreatic cancer KRAS_G12V RNF43 314 66 Race:overall 0.22 -4.12 4.56 1486.37 1.00 873 293 45 21 TRUE 0.04
uterine cancer KRAS_G12V RNF43 45 77 Race:overall -0.51 -4.85 3.87 1513.30 1.00 690 42 74 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V U2AF1 147 65 White 0.95 0.15 1.66 1141.64 1.00 2715 139 57 8 FALSE 1.87
non-small cell lung cancer KRAS_G12V U2AF1 147 65 Race:overall 0.77 -4.09 5.29 1549.71 1.00 2715 139 57 8 FALSE 0.14
colorectal cancer KRAS_G12V LATS1 147 40 White -1.74 -4.50 0.02 871.94 1.00 1559 146 39 1 FALSE 0.91
non-small cell lung cancer KRAS_G12V LATS1 147 59 White -0.13 -1.58 0.96 1085.15 1.00 2715 144 56 3 FALSE 0.07
colorectal cancer KRAS_G12V LATS1 147 40 Race:overall -1.50 -5.91 3.36 1371.57 1.00 1559 146 39 1 FALSE 0.30
non-small cell lung cancer KRAS_G12V LATS1 147 59 Race:overall -0.19 -5.11 4.06 1599.18 1.00 2715 144 56 3 FALSE 0.03
colorectal cancer KRAS_G12V LATS2 147 58 White -6.76 -16.20 -1.32 267.38 1.01 1538 147 58 0 FALSE 0.92
non-small cell lung cancer KRAS_G12V LATS2 147 45 White 0.16 -1.26 1.21 1086.42 1.00 2728 144 42 3 FALSE 0.09
uterine cancer KRAS_G12V LATS2 44 46 White -1.45 -4.19 0.36 1025.26 1.00 717 43 45 1 FALSE 0.67
colorectal cancer KRAS_G12V LATS2 147 58 Race:overall -5.10 -14.47 2.66 170.76 1.02 1538 147 58 0 FALSE 0.71
non-small cell lung cancer KRAS_G12V LATS2 147 45 Race:overall 0.07 -4.26 4.29 1449.21 1.00 2728 144 42 3 FALSE 0.01
uterine cancer KRAS_G12V LATS2 44 46 Race:overall -1.23 -5.77 3.49 1273.56 1.00 717 43 45 1 FALSE 0.23
colorectal cancer KRAS_G12V PTEN 16 11 Asian -0.52 -1.42 0.28 1379.71 1.00 155 15 10 1 TRUE 0.66
colorectal cancer KRAS_G12V PTEN 17 12 Black -0.57 -1.52 0.19 1122.61 1.00 125 17 12 0 TRUE 0.73
colorectal cancer KRAS_G12V PTEN 9 17 Unknown -0.53 -1.40 0.28 1299.90 1.00 108 8 16 1 TRUE 0.69
colorectal cancer KRAS_G12V PTEN 166 141 White -0.53 -1.28 0.08 946.42 1.00 1668 158 133 8 TRUE 0.94
non-small cell lung cancer KRAS_G12V PTEN 152 111 White -5.78 -12.74 -1.50 1196.33 1.00 2751 152 111 0 TRUE 1.26
uterine cancer KRAS_G12V PTEN 9 43 Asian 0.92 -0.06 2.12 1544.06 1.00 60 2 36 7 TRUE 1.00
uterine cancer KRAS_G12V PTEN 7 40 Unknown 0.30 -0.75 1.34 1463.04 1.00 41 4 37 3 TRUE 0.24
uterine cancer KRAS_G12V PTEN 60 504 White 0.02 -0.50 0.55 1574.60 1.00 523 33 477 27 TRUE 0.03
colorectal cancer KRAS_G12V PTEN 208 181 Race:overall -0.54 -1.35 0.14 1193.55 1.00 2056 198 171 10 TRUE 0.83
non-small cell lung cancer KRAS_G12V PTEN 155 124 Race:overall -5.26 -12.17 -0.54 1234.92 1.00 3085 155 124 0 TRUE 1.08
uterine cancer KRAS_G12V PTEN 79 627 Race:overall 0.40 -0.47 1.31 1398.88 1.00 731 40 588 39 TRUE 0.43
colorectal cancer KRAS_G12V BCOR 147 94 White -0.84 -1.95 0.10 1583.95 1.00 1520 143 90 4 FALSE 0.95
non-small cell lung cancer KRAS_G12V BCOR 148 117 White 0.76 0.07 1.37 1240.77 1.00 2674 136 105 12 FALSE 1.70
uterine cancer KRAS_G12V BCOR 44 124 White -0.72 -1.95 0.24 1429.61 1.00 657 40 120 4 FALSE 0.71
colorectal cancer KRAS_G12V BCOR 147 94 Race:overall -0.78 -5.06 3.76 1441.47 1.00 1520 143 90 4 FALSE 0.15
non-small cell lung cancer KRAS_G12V BCOR 148 117 Race:overall 0.64 -3.90 4.60 1337.80 1.00 2674 136 105 12 FALSE 0.13
uterine cancer KRAS_G12V BCOR 44 124 Race:overall -0.62 -4.54 3.87 1421.58 1.00 657 40 120 4 FALSE 0.12
colorectal cancer KRAS_G12V CTNNB1 16 15 Asian -0.57 -1.86 0.28 1075.59 1.00 148 16 15 0 TRUE 0.49
colorectal cancer KRAS_G12V CTNNB1 17 13 Black -0.56 -1.95 0.32 1033.59 1.00 123 17 13 0 TRUE 0.48
colorectal cancer KRAS_G12V CTNNB1 167 124 White -0.36 -1.07 0.31 989.46 1.00 1657 157 114 10 TRUE 0.51
non-small cell lung cancer KRAS_G12V CTNNB1 9 11 Black -1.55 -4.52 0.56 1456.86 1.00 179 9 11 0 TRUE 0.66
non-small cell lung cancer KRAS_G12V CTNNB1 152 88 White -1.22 -2.99 0.08 990.32 1.00 2773 150 86 2 TRUE 0.89
uterine cancer KRAS_G12V CTNNB1 6 15 Asian -1.10 -3.64 0.37 1029.38 1.00 66 6 15 0 TRUE 0.55
uterine cancer KRAS_G12V CTNNB1 50 112 White -0.79 -1.94 0.17 901.13 1.00 723 46 108 4 TRUE 0.81
colorectal cancer KRAS_G12V CTNNB1 200 152 Race:overall -0.50 -1.57 0.30 1111.03 1.00 1928 190 142 10 TRUE 0.53
non-small cell lung cancer KRAS_G12V CTNNB1 164 116 Race:overall -1.41 -3.83 0.36 1381.38 1.00 3281 162 114 2 TRUE 0.72
uterine cancer KRAS_G12V CTNNB1 56 127 Race:overall -0.91 -2.70 0.51 988.14 1.00 789 52 123 4 TRUE 0.57
cancer of unknown primary KRAS_G12V ARID1A 41 105 White 0.16 -0.69 0.95 1427.33 1.00 488 33 97 8 TRUE 0.15
colorectal cancer KRAS_G12V ARID1A 13 22 Asian -0.59 -1.24 0.03 772.70 1.01 121 12 21 1 TRUE 1.22
colorectal cancer KRAS_G12V ARID1A 17 24 Black -0.62 -1.27 -0.05 654.30 1.00 117 17 24 0 TRUE 1.31
colorectal cancer KRAS_G12V ARID1A 9 15 Unknown -0.56 -1.18 0.07 830.84 1.00 108 7 13 2 TRUE 1.15
colorectal cancer KRAS_G12V ARID1A 148 249 White -0.59 -1.14 -0.10 585.99 1.01 1434 135 236 13 TRUE 1.58
non-small cell lung cancer KRAS_G12V ARID1A 9 20 Black -0.92 -4.01 0.75 1480.27 1.00 165 9 20 0 TRUE 0.35
non-small cell lung cancer KRAS_G12V ARID1A 149 231 White -0.09 -0.76 0.51 1461.56 1.00 2570 137 219 12 TRUE 0.11
pancreatic cancer KRAS_G12V ARID1A 24 16 Asian -0.24 -1.35 0.69 1487.38 1.00 43 20 12 4 TRUE 0.19
pancreatic cancer KRAS_G12V ARID1A 314 104 White -0.22 -0.69 0.23 1352.32 1.00 841 291 81 23 TRUE 0.44
uterine cancer KRAS_G12V ARID1A 6 39 Asian 0.91 -0.22 2.03 1426.68 1.00 42 2 35 4 TRUE 0.99
uterine cancer KRAS_G12V ARID1A 7 28 Unknown 1.16 0.13 2.34 1481.42 1.00 42 2 23 5 TRUE 1.42
uterine cancer KRAS_G12V ARID1A 53 427 White 0.72 0.15 1.26 1544.31 1.00 494 21 395 32 TRUE 1.93
cancer of unknown primary KRAS_G12V ARID1A 41 105 Race:overall 0.00 -4.41 4.28 1251.33 1.00 488 33 97 8 TRUE 0.00
colorectal cancer KRAS_G12V ARID1A 187 310 Race:overall -0.59 -1.17 -0.02 679.33 1.01 1780 171 294 16 TRUE 1.38
non-small cell lung cancer KRAS_G12V ARID1A 161 271 Race:overall -0.56 -2.56 0.90 1488.01 1.00 3045 149 259 12 TRUE 0.29
pancreatic cancer KRAS_G12V ARID1A 338 120 Race:overall -0.22 -1.66 1.06 1548.45 1.00 884 311 93 27 TRUE 0.13
uterine cancer KRAS_G12V ARID1A 67 517 Race:overall 0.82 -0.12 1.76 1331.58 1.00 662 26 476 41 TRUE 1.07
colorectal cancer KRAS_G12V PIK3R1 147 95 White -1.69 -3.36 -0.37 1404.09 1.00 1517 145 93 2 TRUE 1.52
non-small cell lung cancer KRAS_G12V PIK3R1 147 41 White 0.23 -1.21 1.36 1439.00 1.00 2732 144 38 3 TRUE 0.14
uterine cancer KRAS_G12V PIK3R1 6 22 Asian -0.02 -0.94 1.36 1078.33 1.00 50 2 18 4 TRUE 0.01
uterine cancer KRAS_G12V PIK3R1 45 215 White -0.33 -1.04 0.32 276.50 1.02 590 37 207 8 TRUE 0.46
colorectal cancer KRAS_G12V PIK3R1 147 95 Race:overall -1.44 -5.62 3.19 1579.20 1.00 1517 145 93 2 TRUE 0.31
non-small cell lung cancer KRAS_G12V PIK3R1 147 41 Race:overall 0.15 -4.74 4.67 1540.52 1.00 2732 144 38 3 TRUE 0.02
uterine cancer KRAS_G12V PIK3R1 56 254 Race:overall -0.23 -1.02 0.63 1035.51 1.01 684 44 242 12 TRUE 0.22
colorectal cancer KRAS_G12V IKZF1 147 69 White -2.27 -4.86 -0.59 1205.17 1.00 1530 146 68 1 TRUE 1.34
non-small cell lung cancer KRAS_G12V IKZF1 147 67 White -1.65 -4.44 0.07 812.60 1.00 2705 146 66 1 TRUE 0.79
colorectal cancer KRAS_G12V IKZF1 147 69 Race:overall -1.85 -6.20 3.28 1446.04 1.00 1530 146 68 1 TRUE 0.38
non-small cell lung cancer KRAS_G12V IKZF1 147 67 Race:overall -1.48 -6.04 3.09 1001.75 1.00 2705 146 66 1 TRUE 0.30
colorectal cancer KRAS_G12V TERT 148 75 White -0.33 -1.59 0.30 3.25 1.35 1530 144 71 4 TRUE 0.25
non-small cell lung cancer KRAS_G12V TERT 147 135 White -1.51 -3.32 -0.19 1273.43 1.00 2643 145 133 2 TRUE 1.24
uterine cancer KRAS_G12V TERT 44 47 White -1.47 -4.16 0.33 1368.18 1.00 708 43 46 1 TRUE 0.68
colorectal cancer KRAS_G12V TERT 148 75 Race:overall -0.34 -4.32 3.00 179.73 1.02 1530 144 71 4 TRUE 0.07
non-small cell lung cancer KRAS_G12V TERT 150 146 Race:overall -1.54 -4.50 1.18 1411.98 1.00 2960 148 144 2 TRUE 0.52
uterine cancer KRAS_G12V TERT 44 47 Race:overall -1.18 -5.62 3.69 1589.00 1.00 708 43 46 1 TRUE 0.22
colorectal cancer KRAS_G12V FAT1 13 15 Asian -1.45 -2.47 -0.58 124.31 1.03 129 13 15 0 FALSE 2.32
colorectal cancer KRAS_G12V FAT1 17 11 Black -1.44 -2.42 -0.56 116.23 1.03 127 17 11 0 FALSE 2.42
colorectal cancer KRAS_G12V FAT1 9 19 Unknown -1.45 -2.43 -0.50 117.24 1.03 111 9 19 0 FALSE 2.36
colorectal cancer KRAS_G12V FAT1 147 180 White -1.38 -2.25 -0.62 70.12 1.05 1470 141 174 6 FALSE 2.65
non-small cell lung cancer KRAS_G12V FAT1 9 12 Black -0.33 -1.81 1.06 1465.14 1.00 176 8 11 1 FALSE 0.19
non-small cell lung cancer KRAS_G12V FAT1 8 15 Unknown -0.67 -2.38 0.70 1436.51 1.00 152 8 15 0 FALSE 0.40
non-small cell lung cancer KRAS_G12V FAT1 147 261 White -0.46 -1.14 0.13 1310.74 1.00 2547 138 252 9 FALSE 0.79
uterine cancer KRAS_G12V FAT1 45 150 White -0.44 -1.33 0.34 779.65 1.00 672 39 144 6 FALSE 0.50
colorectal cancer KRAS_G12V FAT1 186 225 Race:overall -1.43 -2.33 -0.62 95.89 1.04 1837 180 219 6 FALSE 2.62
non-small cell lung cancer KRAS_G12V FAT1 167 301 Race:overall -0.51 -1.80 0.58 1399.54 1.00 3188 157 291 10 FALSE 0.40
uterine cancer KRAS_G12V FAT1 55 176 Race:overall -0.45 -1.41 0.42 813.52 1.00 783 48 169 7 FALSE 0.44
colorectal cancer KRAS_G12V FGFR4 147 39 White -1.71 -4.42 0.17 1123.36 1.00 1559 146 38 1 TRUE 0.83
colorectal cancer KRAS_G12V FGFR4 147 39 Race:overall -1.43 -6.01 3.72 1340.53 1.00 1559 146 38 1 TRUE 0.26
colorectal cancer KRAS_G12V CIC 147 111 White -0.38 -1.22 0.36 1474.24 1.00 1511 140 104 7 TRUE 0.46
non-small cell lung cancer KRAS_G12V CIC 147 81 White -0.48 -1.95 0.56 1333.86 1.00 2704 144 78 3 TRUE 0.35
uterine cancer KRAS_G12V CIC 45 55 White 0.50 -0.60 1.42 1232.37 1.00 713 40 50 5 TRUE 0.47
colorectal cancer KRAS_G12V CIC 147 111 Race:overall -0.32 -4.51 4.21 1706.60 1.00 1511 140 104 7 TRUE 0.06
non-small cell lung cancer KRAS_G12V CIC 147 81 Race:overall -0.44 -4.93 4.07 1457.25 1.00 2704 144 78 3 TRUE 0.08
uterine cancer KRAS_G12V CIC 45 55 Race:overall 0.38 -3.71 4.66 1523.26 1.00 713 40 50 5 TRUE 0.07
colorectal cancer KRAS_G12V KDM6A 147 49 White 0.12 -0.98 1.00 1518.43 1.00 1554 142 44 5 FALSE 0.09
non-small cell lung cancer KRAS_G12V KDM6A 147 45 White -1.30 -4.43 0.57 1513.55 1.00 2728 146 44 1 FALSE 0.52
pancreatic cancer KRAS_G12V KDM6A 313 56 White 0.25 -0.36 0.81 1437.27 1.00 878 296 39 17 FALSE 0.38
uterine cancer KRAS_G12V KDM6A 44 41 White -1.30 -4.10 0.55 1395.70 1.00 719 43 40 1 FALSE 0.56
colorectal cancer KRAS_G12V KDM6A 147 49 Race:overall 0.08 -4.52 4.38 1637.87 1.00 1554 142 44 5 FALSE 0.01
non-small cell lung cancer KRAS_G12V KDM6A 147 45 Race:overall -1.18 -5.84 3.70 1347.83 1.00 2728 146 44 1 FALSE 0.22
pancreatic cancer KRAS_G12V KDM6A 313 56 Race:overall 0.17 -4.19 4.53 1503.37 1.00 878 296 39 17 FALSE 0.03
uterine cancer KRAS_G12V KDM6A 44 41 Race:overall -1.06 -5.64 3.81 1576.05 1.00 719 43 40 1 FALSE 0.19
colorectal cancer KRAS_G12V NCOR1 13 12 Asian -0.80 -3.31 0.45 1401.68 1.00 127 13 12 0 FALSE 0.39
colorectal cancer KRAS_G12V NCOR1 150 108 White -0.49 -1.39 0.26 1255.18 1.00 1514 143 101 7 FALSE 0.63
non-small cell lung cancer KRAS_G12V NCOR1 147 82 White -1.97 -4.84 -0.12 1147.38 1.01 2697 146 81 1 FALSE 0.97
uterine cancer KRAS_G12V NCOR1 44 76 White -6.41 -16.05 -1.25 936.34 1.00 708 44 76 0 FALSE 0.56
colorectal cancer KRAS_G12V NCOR1 163 120 Race:overall -0.62 -2.06 0.48 1362.81 1.00 1641 156 113 7 FALSE 0.45
non-small cell lung cancer KRAS_G12V NCOR1 147 82 Race:overall -1.60 -6.25 3.51 1298.26 1.00 2697 146 81 1 FALSE 0.31
uterine cancer KRAS_G12V NCOR1 44 76 Race:overall -4.63 -11.57 2.36 1059.14 1.00 708 44 76 0 FALSE 0.74
colorectal cancer KRAS_G12V POLE 13 13 Asian -1.70 -4.03 -0.28 661.05 1.01 129 13 13 0 TRUE 0.88
colorectal cancer KRAS_G12V POLE 147 115 White -1.50 -2.92 -0.51 274.28 1.01 1502 144 112 3 TRUE 1.73
non-small cell lung cancer KRAS_G12V POLE 148 112 White 0.61 -0.08 1.21 388.09 1.00 2674 138 102 10 TRUE 1.11
uterine cancer KRAS_G12V POLE 44 91 White -5.80 -16.03 -1.41 308.80 1.01 699 44 91 0 TRUE 0.85
colorectal cancer KRAS_G12V POLE 160 128 Race:overall -1.58 -3.51 -0.23 625.59 1.01 1631 157 125 3 TRUE 1.09
non-small cell lung cancer KRAS_G12V POLE 148 112 Race:overall 0.54 -4.05 4.67 1602.11 1.00 2674 138 102 10 TRUE 0.11
uterine cancer KRAS_G12V POLE 44 91 Race:overall -4.33 -11.99 2.15 1018.95 1.00 699 44 91 0 TRUE 0.67
non-small cell lung cancer KRAS_G12V CUL3 148 64 White 0.12 -1.08 1.09 1341.28 1.00 2716 144 60 4 FALSE 0.08
non-small cell lung cancer KRAS_G12V CUL3 148 64 Race:overall 0.10 -4.46 4.59 1585.93 1.00 2716 144 60 4 FALSE 0.02
colorectal cancer KRAS_G12V ABL1 167 59 White -0.76 -2.20 0.40 1147.02 1.00 1717 164 56 3 TRUE 0.61
colorectal cancer KRAS_G12V ABL1 167 59 Race:overall -0.68 -5.10 3.69 1202.15 1.01 1717 164 56 3 TRUE 0.13
colorectal cancer KRAS_G12V FOXP1 147 56 White -0.66 -2.06 0.40 1346.30 1.00 1546 144 53 3 FALSE 0.52
colorectal cancer KRAS_G12V FOXP1 147 56 Race:overall -0.53 -4.92 4.46 1637.55 1.00 1546 144 53 3 FALSE 0.09
colorectal cancer KRAS_G12V NOTCH2 147 64 White -2.29 -5.23 -0.41 803.81 1.01 1540 146 63 1 TRUE 1.27
non-small cell lung cancer KRAS_G12V NOTCH2 147 98 White -0.09 -1.03 0.79 1237.98 1.00 2687 142 93 5 TRUE 0.07
uterine cancer KRAS_G12V NOTCH2 44 41 White -5.64 -15.12 -0.57 1460.94 1.00 718 44 41 0 TRUE 0.74
colorectal cancer KRAS_G12V NOTCH2 147 64 Race:overall -1.87 -6.12 3.01 1339.37 1.00 1540 146 63 1 TRUE 0.39
non-small cell lung cancer KRAS_G12V NOTCH2 147 98 Race:overall -0.04 -4.38 4.19 1543.75 1.00 2687 142 93 5 TRUE 0.01
uterine cancer KRAS_G12V NOTCH2 44 41 Race:overall -4.15 -11.89 2.58 1420.03 1.00 718 44 41 0 TRUE 0.61
non-small cell lung cancer KRAS_G12V DDR2 147 82 White -0.13 -1.34 0.82 1188.15 1.00 2692 143 78 4 TRUE 0.09
uterine cancer KRAS_G12V DDR2 44 47 White -5.47 -15.02 -0.69 662.07 1.01 720 44 47 0 TRUE 0.76
non-small cell lung cancer KRAS_G12V DDR2 147 82 Race:overall -0.09 -4.37 4.40 1276.67 1.00 2692 143 78 4 TRUE 0.02
uterine cancer KRAS_G12V DDR2 44 47 Race:overall -4.10 -11.30 2.22 1358.54 1.00 720 44 47 0 TRUE 0.63
colorectal cancer KRAS_G12V TGFBR2 148 93 White -0.39 -1.34 0.43 1409.25 1.00 1512 142 87 6 TRUE 0.41
non-small cell lung cancer KRAS_G12V TGFBR2 147 48 White -0.42 -2.18 0.87 1228.75 1.00 2728 145 46 2 TRUE 0.22
colorectal cancer KRAS_G12V TGFBR2 148 93 Race:overall -0.33 -4.60 4.09 1550.97 1.00 1512 142 87 6 TRUE 0.06
non-small cell lung cancer KRAS_G12V TGFBR2 147 48 Race:overall -0.41 -4.86 4.10 1392.30 1.00 2728 145 46 2 TRUE 0.07
colorectal cancer KRAS_G12V SMO 166 57 White -0.70 -1.99 0.32 974.87 1.00 1717 163 54 3 TRUE 0.61
non-small cell lung cancer KRAS_G12V SMO 152 64 White -0.76 -2.66 0.57 934.39 1.01 2797 150 62 2 TRUE 0.46
uterine cancer KRAS_G12V SMO 50 41 White -5.67 -14.72 -0.68 861.48 1.00 793 50 41 0 TRUE 0.80
colorectal cancer KRAS_G12V SMO 166 57 Race:overall -0.57 -4.84 3.96 1382.92 1.00 1717 163 54 3 TRUE 0.11
non-small cell lung cancer KRAS_G12V SMO 152 64 Race:overall -0.59 -5.39 4.13 1502.51 1.00 2797 150 62 2 TRUE 0.10
uterine cancer KRAS_G12V SMO 50 41 Race:overall -4.12 -11.50 2.65 937.39 1.00 793 50 41 0 TRUE 0.61
colorectal cancer KRAS_G12V RPS6KA4 147 46 White -1.88 -4.65 -0.04 1475.66 1.00 1551 146 45 1 FALSE 0.93
colorectal cancer KRAS_G12V RPS6KA4 147 46 Race:overall -1.56 -6.41 3.98 1513.72 1.00 1551 146 45 1 FALSE 0.29
colorectal cancer KRAS_G12V KMT2A 147 122 White -1.21 -2.46 -0.20 647.75 1.01 1498 143 118 4 FALSE 1.43
non-small cell lung cancer KRAS_G12V KMT2A 147 99 White 0.13 -0.83 0.89 1303.34 1.00 2683 141 93 6 FALSE 0.11
uterine cancer KRAS_G12V KMT2A 44 88 White -2.15 -4.99 -0.24 1334.29 1.00 702 43 87 1 FALSE 1.12
colorectal cancer KRAS_G12V KMT2A 147 122 Race:overall -1.05 -5.19 4.18 1328.19 1.00 1498 143 118 4 FALSE 0.21
non-small cell lung cancer KRAS_G12V KMT2A 147 99 Race:overall 0.10 -4.60 4.57 1446.17 1.00 2683 141 93 6 FALSE 0.02
uterine cancer KRAS_G12V KMT2A 44 88 Race:overall -1.89 -6.29 3.05 1414.47 1.00 702 43 87 1 FALSE 0.41
colorectal cancer KRAS_G12V JAK3 166 51 White -5.97 -14.72 -1.20 1453.98 1.00 1719 166 51 0 TRUE 0.99
non-small cell lung cancer KRAS_G12V JAK3 153 73 White 0.47 -0.47 1.41 273.95 1.00 2791 147 67 6 TRUE 0.50
colorectal cancer KRAS_G12V JAK3 166 51 Race:overall -4.51 -11.98 3.06 1506.69 1.00 1719 166 51 0 TRUE 0.65
non-small cell lung cancer KRAS_G12V JAK3 153 73 Race:overall 0.37 -3.63 4.23 1446.82 1.00 2791 147 67 6 TRUE 0.07
non-small cell lung cancer KRAS_G12V PAK7 8 14 Unknown 0.56 -1.09 1.83 1465.43 1.00 156 7 13 1 FALSE 0.38
non-small cell lung cancer KRAS_G12V PAK7 147 107 White 0.64 -0.07 1.26 1529.91 1.00 2680 137 97 10 FALSE 1.26
non-small cell lung cancer KRAS_G12V PAK7 155 121 Race:overall 0.59 -0.86 1.87 1387.75 1.00 2836 144 110 11 FALSE 0.41
non-small cell lung cancer KRAS_G12V STAG2 147 85 White -0.55 -2.02 0.54 1317.93 1.00 2693 144 82 3 TRUE 0.40
uterine cancer KRAS_G12V STAG2 44 70 White -6.09 -15.63 -1.27 1006.20 1.00 710 44 70 0 TRUE 0.58
non-small cell lung cancer KRAS_G12V STAG2 147 85 Race:overall -0.55 -5.00 4.03 1368.82 1.00 2693 144 82 3 TRUE 0.10
uterine cancer KRAS_G12V STAG2 44 70 Race:overall -4.42 -11.21 2.39 476.12 1.00 710 44 70 0 TRUE 0.73
colorectal cancer KRAS_G12V BRCA2 13 18 Asian -1.08 -2.09 -0.19 1069.90 1.00 132 12 17 1 TRUE 1.53
colorectal cancer KRAS_G12V BRCA2 17 13 Black -1.14 -2.29 -0.25 971.73 1.00 121 17 13 0 TRUE 1.55
colorectal cancer KRAS_G12V BRCA2 147 149 White -1.09 -1.99 -0.34 996.74 1.00 1495 142 144 5 TRUE 1.95
non-small cell lung cancer KRAS_G12V BRCA2 148 110 White -0.49 -1.67 0.42 1417.69 1.00 2673 144 106 4 TRUE 0.43
uterine cancer KRAS_G12V BRCA2 44 109 White -2.70 -6.43 -0.36 146.40 1.04 691 44 109 0 TRUE 1.13
colorectal cancer KRAS_G12V BRCA2 177 180 Race:overall -1.10 -2.07 -0.26 992.76 1.00 1748 171 174 6 TRUE 1.75
non-small cell lung cancer KRAS_G12V BRCA2 151 122 Race:overall -0.67 -3.75 1.60 1548.11 1.00 2989 147 118 4 TRUE 0.22
uterine cancer KRAS_G12V BRCA2 49 120 Race:overall -2.16 -5.09 0.07 426.27 1.01 745 48 119 1 TRUE 0.96
colorectal cancer KRAS_G12V NOTCH3 13 18 Asian -0.94 -1.89 -0.15 897.30 1.00 125 13 18 0 TRUE 1.43
colorectal cancer KRAS_G12V NOTCH3 17 12 Black -0.90 -1.82 -0.10 905.59 1.00 123 16 11 1 TRUE 1.38
colorectal cancer KRAS_G12V NOTCH3 9 13 Unknown -0.93 -1.87 -0.14 993.83 1.00 107 9 13 0 TRUE 1.42
colorectal cancer KRAS_G12V NOTCH3 148 154 White -0.89 -1.71 -0.17 719.52 1.00 1478 141 147 7 TRUE 1.66
non-small cell lung cancer KRAS_G12V NOTCH3 147 106 White 0.03 -0.94 0.82 730.07 1.00 2678 141 100 6 TRUE 0.02
uterine cancer KRAS_G12V NOTCH3 44 72 White -5.81 -16.06 -1.25 347.90 1.01 700 44 72 0 TRUE 0.88
colorectal cancer KRAS_G12V NOTCH3 187 197 Race:overall -0.91 -1.79 -0.17 827.33 1.00 1833 179 189 8 TRUE 1.60
non-small cell lung cancer KRAS_G12V NOTCH3 147 106 Race:overall 0.00 -4.27 4.24 1318.13 1.00 2678 141 100 6 TRUE 0.00
uterine cancer KRAS_G12V NOTCH3 44 72 Race:overall -4.29 -12.22 1.86 886.92 1.00 700 44 72 0 TRUE 0.68
colorectal cancer KRAS_G12V NOTCH4 147 99 White -1.28 -2.61 -0.19 1441.04 1.00 1508 144 96 3 TRUE 1.36
non-small cell lung cancer KRAS_G12V NOTCH4 147 117 White 0.27 -0.56 0.98 1338.21 1.00 2667 139 109 8 TRUE 0.32
uterine cancer KRAS_G12V NOTCH4 45 52 White -0.66 -2.42 0.68 1265.17 1.00 714 43 50 2 TRUE 0.38
colorectal cancer KRAS_G12V NOTCH4 147 99 Race:overall -1.01 -5.46 3.81 1537.95 1.00 1508 144 96 3 TRUE 0.20
non-small cell lung cancer KRAS_G12V NOTCH4 147 117 Race:overall 0.15 -4.30 4.37 1355.82 1.00 2667 139 109 8 TRUE 0.03
uterine cancer KRAS_G12V NOTCH4 45 52 Race:overall -0.60 -4.81 3.64 1466.81 1.00 714 43 50 2 TRUE 0.12
colorectal cancer KRAS_G12V FGFR3 166 45 White -0.93 -2.72 0.36 913.97 1.00 1726 164 43 2 TRUE 0.61
colorectal cancer KRAS_G12V FGFR3 166 45 Race:overall -0.71 -4.78 4.18 1248.02 1.00 1726 164 43 2 TRUE 0.13
non-small cell lung cancer KRAS_G12V MAP3K13 148 42 White 0.85 -0.16 1.77 1165.40 1.00 2733 143 37 5 FALSE 1.11
non-small cell lung cancer KRAS_G12V MAP3K13 148 42 Race:overall 0.74 -3.60 4.64 1500.73 1.00 2733 143 37 5 FALSE 0.15
colorectal cancer KRAS_G12V IGF1R 147 69 White -1.38 -3.17 -0.06 1399.30 1.00 1537 145 67 2 TRUE 1.08
non-small cell lung cancer KRAS_G12V IGF1R 147 39 White -5.32 -14.48 -0.46 887.60 1.00 2731 147 39 0 TRUE 0.71
colorectal cancer KRAS_G12V IGF1R 147 69 Race:overall -1.20 -5.41 3.54 1441.19 1.00 1537 145 67 2 TRUE 0.24
non-small cell lung cancer KRAS_G12V IGF1R 147 39 Race:overall -4.03 -11.24 2.45 1179.66 1.00 2731 147 39 0 TRUE 0.61
non-small cell lung cancer KRAS_G12V KEAP1 9 28 Black 0.11 -1.08 1.29 1402.54 1.00 161 7 26 2 FALSE 0.07
non-small cell lung cancer KRAS_G12V KEAP1 8 19 Unknown -0.02 -1.26 1.11 1458.54 1.00 148 7 18 1 FALSE 0.01
non-small cell lung cancer KRAS_G12V KEAP1 147 461 White -0.09 -0.56 0.36 1192.71 1.00 2349 126 440 21 FALSE 0.15
non-small cell lung cancer KRAS_G12V KEAP1 167 532 Race:overall -0.05 -1.07 0.89 1320.28 1.00 2962 143 508 24 FALSE 0.04
colorectal cancer KRAS_G12V KDM5C 17 12 Black -1.92 -5.53 0.19 1212.09 1.00 124 17 12 0 FALSE 0.75
colorectal cancer KRAS_G12V KDM5C 147 51 White -1.29 -3.20 0.06 1433.24 1.00 1551 145 49 2 FALSE 0.92
non-small cell lung cancer KRAS_G12V KDM5C 147 87 White 0.62 -0.22 1.35 1461.06 1.00 2695 139 79 8 FALSE 0.91
uterine cancer KRAS_G12V KDM5C 45 53 White -0.15 -1.64 1.03 1122.74 1.00 715 42 50 3 FALSE 0.08
colorectal cancer KRAS_G12V KDM5C 164 63 Race:overall -1.51 -3.97 0.43 1390.06 1.00 1675 162 61 2 FALSE 0.73
non-small cell lung cancer KRAS_G12V KDM5C 147 87 Race:overall 0.51 -4.05 4.89 1339.88 1.00 2695 139 79 8 FALSE 0.09
uterine cancer KRAS_G12V KDM5C 45 53 Race:overall -0.14 -4.38 4.19 1497.37 1.00 715 42 50 3 FALSE 0.02
non-small cell lung cancer KRAS_G12V CDKN2A 9 18 Black 0.26 -1.08 1.58 1491.76 1.00 174 7 16 2 TRUE 0.15
non-small cell lung cancer KRAS_G12V CDKN2A 9 20 Unknown -0.42 -2.33 0.88 1420.80 1.00 150 9 20 0 TRUE 0.21
non-small cell lung cancer KRAS_G12V CDKN2A 153 218 White -0.04 -0.68 0.54 1623.65 1.00 2665 142 207 11 TRUE 0.05
pancreatic cancer KRAS_G12V CDKN2A 25 11 Asian 0.35 -0.16 0.93 1451.69 1.00 49 20 6 5 TRUE 0.74
pancreatic cancer KRAS_G12V CDKN2A 19 15 Unknown 0.31 -0.31 0.81 1398.77 1.00 53 15 11 4 TRUE 0.60
pancreatic cancer KRAS_G12V CDKN2A 326 250 White 0.33 0.04 0.61 1024.31 1.00 793 250 174 76 TRUE 1.66
non-small cell lung cancer KRAS_G12V CDKN2A 174 271 Race:overall -0.09 -1.35 0.97 1616.01 1.00 3321 161 258 13 TRUE 0.06
pancreatic cancer KRAS_G12V CDKN2A 370 276 Race:overall 0.33 -0.16 0.78 1373.18 1.00 895 285 191 85 TRUE 0.78
colorectal cancer KRAS_G12V EPHB1 147 65 White -1.31 -3.23 0.02 1213.61 1.00 1533 145 63 2 FALSE 0.98
non-small cell lung cancer KRAS_G12V EPHB1 9 11 Black -0.34 -1.69 1.14 1276.33 1.00 175 8 10 1 FALSE 0.21
non-small cell lung cancer KRAS_G12V EPHB1 147 135 White -0.52 -1.55 0.31 1017.36 1.00 2653 143 131 4 FALSE 0.57
colorectal cancer KRAS_G12V EPHB1 147 65 Race:overall -1.09 -5.59 3.62 1310.07 1.00 1533 145 63 2 FALSE 0.19
non-small cell lung cancer KRAS_G12V EPHB1 156 146 Race:overall -0.43 -1.70 0.79 1398.03 1.00 2828 151 141 5 FALSE 0.29
colorectal cancer KRAS_G12V IRS2 148 71 White -0.90 -2.26 0.11 1400.02 1.00 1532 145 68 3 FALSE 0.86
non-small cell lung cancer KRAS_G12V IRS2 147 68 White 0.33 -0.68 1.17 1207.12 1.00 2709 142 63 5 FALSE 0.31
uterine cancer KRAS_G12V IRS2 44 55 White -1.64 -4.78 0.21 1160.81 1.00 708 43 54 1 FALSE 0.74
colorectal cancer KRAS_G12V IRS2 148 71 Race:overall -0.77 -5.15 3.44 1530.03 1.00 1532 145 68 3 FALSE 0.15
non-small cell lung cancer KRAS_G12V IRS2 147 68 Race:overall 0.28 -4.27 4.57 1540.68 1.00 2709 142 63 5 FALSE 0.05
uterine cancer KRAS_G12V IRS2 44 55 Race:overall -1.32 -5.52 3.44 1257.51 1.00 708 43 54 1 FALSE 0.26
colorectal cancer KRAS_G12V FANCA 147 51 White -0.58 -2.04 0.56 1234.63 1.00 1549 144 48 3 TRUE 0.42
non-small cell lung cancer KRAS_G12V FANCA 147 59 White 0.22 -0.94 1.21 1127.37 1.00 2717 143 55 4 TRUE 0.16
colorectal cancer KRAS_G12V FANCA 147 51 Race:overall -0.48 -4.90 4.41 1478.19 1.00 1549 144 48 3 TRUE 0.08
non-small cell lung cancer KRAS_G12V FANCA 147 59 Race:overall 0.14 -4.02 4.60 1309.91 1.00 2717 143 55 4 TRUE 0.02
non-small cell lung cancer KRAS_G12V IL7R 147 69 White -0.32 -1.70 0.79 1390.67 1.00 2711 144 66 3 FALSE 0.21
non-small cell lung cancer KRAS_G12V IL7R 147 69 Race:overall -0.26 -4.75 4.05 1437.29 1.00 2711 144 66 3 FALSE 0.05
uterine cancer KRAS_G12V PPP2R1A 44 133 White -0.08 -0.94 0.68 1312.62 1.00 638 37 126 7 FALSE 0.07
uterine cancer KRAS_G12V PPP2R1A 44 133 Race:overall -0.16 -4.45 3.94 1487.83 1.00 638 37 126 7 FALSE 0.03
colorectal cancer KRAS_G12V PIK3CB 147 48 White -1.94 -4.70 -0.22 430.19 1.00 1556 146 47 1 FALSE 1.00
colorectal cancer KRAS_G12V PIK3CB 147 48 Race:overall -1.72 -6.11 3.00 708.05 1.00 1556 146 47 1 FALSE 0.38
colorectal cancer KRAS_G12V ERBB3 13 11 Asian -0.98 -3.14 0.31 661.38 1.00 127 13 11 0 TRUE 0.52
colorectal cancer KRAS_G12V ERBB3 147 94 White -0.76 -2.23 0.12 89.80 1.03 1517 142 89 5 TRUE 0.81
uterine cancer KRAS_G12V ERBB3 44 62 White -0.84 -2.59 0.49 888.33 1.01 700 42 60 2 TRUE 0.53
colorectal cancer KRAS_G12V ERBB3 160 105 Race:overall -0.84 -2.28 0.35 262.85 1.01 1644 155 100 5 TRUE 0.61
uterine cancer KRAS_G12V ERBB3 44 62 Race:overall -0.71 -4.72 3.87 1343.83 1.00 700 42 60 2 TRUE 0.14
colorectal cancer KRAS_G12V SMAD4 17 23 Asian 0.47 0.00 1.05 842.05 1.00 146 11 17 6 TRUE 1.05
colorectal cancer KRAS_G12V SMAD4 17 27 Black 0.39 -0.09 0.89 1288.38 1.00 114 14 24 3 TRUE 0.90
colorectal cancer KRAS_G12V SMAD4 9 24 Unknown 0.39 -0.13 0.91 1232.35 1.00 100 7 22 2 TRUE 0.86
colorectal cancer KRAS_G12V SMAD4 169 274 White 0.36 0.00 0.74 1143.63 1.00 1542 139 244 30 TRUE 1.24
non-small cell lung cancer KRAS_G12V SMAD4 152 89 White 0.01 -1.01 0.85 1532.65 1.00 2774 147 84 5 TRUE 0.01
pancreatic cancer KRAS_G12V SMAD4 25 17 Asian 0.10 -0.66 0.66 527.92 1.01 43 20 12 5 TRUE 0.11
pancreatic cancer KRAS_G12V SMAD4 323 242 White 0.13 -0.20 0.42 141.17 1.02 786 257 176 66 TRUE 0.39
colorectal cancer KRAS_G12V SMAD4 212 348 Race:overall 0.41 -0.02 0.85 1053.77 1.00 1902 171 307 41 TRUE 1.16
non-small cell lung cancer KRAS_G12V SMAD4 155 100 Race:overall -0.25 -3.20 2.12 1590.36 1.00 3111 150 95 5 TRUE 0.07
pancreatic cancer KRAS_G12V SMAD4 348 259 Race:overall 0.11 -0.63 0.75 836.91 1.00 829 277 188 71 TRUE 0.12
colorectal cancer KRAS_G12V ATM 16 17 Asian -0.08 -0.72 0.48 975.05 1.00 151 15 16 1 TRUE 0.11
colorectal cancer KRAS_G12V ATM 18 15 Black -0.05 -0.67 0.57 804.30 1.00 127 16 13 2 TRUE 0.06
colorectal cancer KRAS_G12V ATM 10 19 Unknown -0.05 -0.63 0.54 970.78 1.00 111 8 17 2 TRUE 0.07
colorectal cancer KRAS_G12V ATM 167 176 White -0.08 -0.56 0.37 599.40 1.01 1637 153 162 14 TRUE 0.13
non-small cell lung cancer KRAS_G12V ATM 9 15 Black 0.14 -1.66 1.31 1517.37 1.00 177 9 15 0 TRUE 0.07
non-small cell lung cancer KRAS_G12V ATM 9 11 Unknown 0.77 -0.51 2.02 1549.76 1.00 162 7 9 2 TRUE 0.65
non-small cell lung cancer KRAS_G12V ATM 154 245 White 0.55 0.04 1.01 1632.66 1.00 2657 134 225 20 TRUE 1.57
uterine cancer KRAS_G12V ATM 7 18 Asian 0.28 -0.95 1.95 635.41 1.00 71 4 15 3 TRUE 0.15
uterine cancer KRAS_G12V ATM 50 132 White -0.39 -1.31 0.36 372.85 1.01 755 46 128 4 TRUE 0.41
colorectal cancer KRAS_G12V ATM 211 227 Race:overall -0.06 -0.60 0.43 856.12 1.00 2026 192 208 19 TRUE 0.09
non-small cell lung cancer KRAS_G12V ATM 175 284 Race:overall 0.43 -0.69 1.41 1546.10 1.00 3331 153 262 22 TRUE 0.38
uterine cancer KRAS_G12V ATM 57 150 Race:overall -0.05 -1.30 1.46 1202.56 1.00 826 50 143 7 TRUE 0.03
colorectal cancer KRAS_G12V RB1 166 57 White -0.33 -1.54 0.68 1365.37 1.00 1723 162 53 4 TRUE 0.26
non-small cell lung cancer KRAS_G12V RB1 9 18 Black -1.32 -3.36 0.15 1389.31 1.00 172 9 18 0 TRUE 0.87
non-small cell lung cancer KRAS_G12V RB1 9 11 Unknown -1.37 -3.35 0.10 1160.50 1.00 159 9 11 0 TRUE 0.87
non-small cell lung cancer KRAS_G12V RB1 152 164 White -1.07 -2.30 -0.12 1088.84 1.00 2702 148 160 4 TRUE 1.33
uterine cancer KRAS_G12V RB1 50 75 White -5.94 -15.31 -1.34 747.64 1.02 775 50 75 0 TRUE 0.75
colorectal cancer KRAS_G12V RB1 166 57 Race:overall -0.27 -4.57 4.24 1329.27 1.00 1723 162 53 4 TRUE 0.05
non-small cell lung cancer KRAS_G12V RB1 173 220 Race:overall -1.26 -2.87 -0.04 1086.46 1.00 3352 169 216 4 TRUE 1.09
uterine cancer KRAS_G12V RB1 50 75 Race:overall -4.37 -11.23 1.82 848.99 1.00 775 50 75 0 TRUE 0.75
cancer of unknown primary KRAS_G12V KMT2D 38 110 White -0.49 -1.60 0.44 206.00 1.02 486 33 105 5 FALSE 0.45
colorectal cancer KRAS_G12V KMT2D 13 36 Asian -1.34 -2.29 -0.62 503.15 1.01 119 13 36 0 FALSE 2.77
colorectal cancer KRAS_G12V KMT2D 17 23 Black -1.34 -2.25 -0.64 664.66 1.01 115 17 23 0 FALSE 2.89
colorectal cancer KRAS_G12V KMT2D 9 24 Unknown -1.33 -2.24 -0.60 803.79 1.01 104 9 24 0 FALSE 2.92
colorectal cancer KRAS_G12V KMT2D 147 298 White -1.22 -1.82 -0.64 764.28 1.01 1424 136 287 11 FALSE 4.03
non-small cell lung cancer KRAS_G12V KMT2D 9 22 Black -0.34 -1.91 0.94 1462.66 1.00 167 8 21 1 FALSE 0.19
non-small cell lung cancer KRAS_G12V KMT2D 8 20 Unknown -0.66 -2.71 0.63 1528.52 1.00 147 8 20 0 FALSE 0.37
non-small cell lung cancer KRAS_G12V KMT2D 147 266 White -0.18 -0.77 0.42 1385.53 1.00 2556 135 254 12 FALSE 0.25
pancreatic cancer KRAS_G12V KMT2D 314 54 White -0.32 -1.02 0.33 1202.92 1.00 878 303 43 11 FALSE 0.45
uterine cancer KRAS_G12V KMT2D 44 213 White -0.60 -1.41 0.11 1171.27 1.00 618 38 207 6 FALSE 0.90
cancer of unknown primary KRAS_G12V KMT2D 38 110 Race:overall -0.30 -4.00 4.42 1254.36 1.00 486 33 105 5 FALSE 0.06
colorectal cancer KRAS_G12V KMT2D 186 381 Race:overall -1.31 -2.07 -0.67 600.99 1.01 1762 175 370 11 FALSE 3.47
non-small cell lung cancer KRAS_G12V KMT2D 167 322 Race:overall -0.42 -1.74 0.67 1544.23 1.00 3185 154 309 13 FALSE 0.31
pancreatic cancer KRAS_G12V KMT2D 314 54 Race:overall -0.29 -4.55 4.08 1648.06 1.00 878 303 43 11 FALSE 0.05
uterine cancer KRAS_G12V KMT2D 55 260 Race:overall -0.42 -1.50 0.64 1380.56 1.00 811 46 251 9 FALSE 0.37
colorectal cancer KRAS_G12V TSC2 147 91 White -1.69 -3.39 -0.35 1500.70 1.00 1522 145 89 2 TRUE 1.51
non-small cell lung cancer KRAS_G12V TSC2 147 63 White 0.40 -0.66 1.27 1511.06 1.00 2715 142 58 5 TRUE 0.39
uterine cancer KRAS_G12V TSC2 44 62 White -0.85 -2.83 0.50 1245.13 1.00 711 42 60 2 TRUE 0.52
colorectal cancer KRAS_G12V TSC2 147 91 Race:overall -1.42 -5.85 3.31 1443.80 1.00 1522 145 89 2 TRUE 0.29
non-small cell lung cancer KRAS_G12V TSC2 147 63 Race:overall 0.39 -4.12 4.88 1407.01 1.00 2715 142 58 5 TRUE 0.07
uterine cancer KRAS_G12V TSC2 44 62 Race:overall -0.70 -4.79 3.92 1438.41 1.00 711 42 60 2 TRUE 0.14
colorectal cancer KRAS_G12V APC 21 163 Asian 0.10 -0.50 0.68 1668.94 1.00 70 7 149 14 TRUE 0.13
colorectal cancer KRAS_G12V APC 28 187 Black 0.42 -0.17 1.10 1519.23 1.00 37 2 161 26 TRUE 0.74
colorectal cancer KRAS_G12V APC 8 47 Race:Other 0.32 -0.39 1.04 1458.23 1.00 19 1 40 7 TRUE 0.43
colorectal cancer KRAS_G12V APC 12 156 Unknown -0.07 -0.84 0.58 1451.14 1.00 26 4 148 8 TRUE 0.07
colorectal cancer KRAS_G12V APC 230 1977 White 0.17 -0.11 0.47 1568.70 1.00 608 51 1798 179 TRUE 0.60
non-small cell lung cancer KRAS_G12V APC 9 12 Black -0.30 -2.23 1.46 1467.64 1.00 179 8 11 1 TRUE 0.13
non-small cell lung cancer KRAS_G12V APC 152 125 White -0.79 -2.03 0.21 1555.77 1.00 2742 149 122 3 TRUE 0.77
uterine cancer KRAS_G12V APC 50 108 White -1.42 -3.16 -0.11 1419.08 1.00 778 48 106 2 TRUE 1.12
colorectal cancer KRAS_G12V APC 299 2530 Race:overall 0.19 -0.33 0.68 1531.50 1.00 760 65 2296 234 TRUE 0.35
non-small cell lung cancer KRAS_G12V APC 164 149 Race:overall -0.57 -2.27 1.05 1492.21 1.00 3256 160 145 4 TRUE 0.30
uterine cancer KRAS_G12V APC 50 108 Race:overall -1.28 -5.64 3.66 1508.00 1.00 778 48 106 2 TRUE 0.26
colorectal cancer KRAS_G12V ERBB2 166 84 White -0.76 -1.89 0.19 1298.05 1.00 1693 162 80 4 TRUE 0.82
non-small cell lung cancer KRAS_G12V ERBB2 152 101 White -2.12 -4.70 -0.42 1495.17 1.00 2761 151 100 1 TRUE 1.19
uterine cancer KRAS_G12V ERBB2 50 45 White -5.66 -14.63 -0.70 971.59 1.00 787 50 45 0 TRUE 0.79
colorectal cancer KRAS_G12V ERBB2 166 84 Race:overall -0.65 -4.81 3.84 1536.02 1.00 1693 162 80 4 TRUE 0.12
non-small cell lung cancer KRAS_G12V ERBB2 155 114 Race:overall -2.11 -5.42 0.95 1433.64 1.00 3094 154 113 1 TRUE 0.68
uterine cancer KRAS_G12V ERBB2 50 45 Race:overall -4.12 -11.47 3.15 1069.52 1.00 787 50 45 0 TRUE 0.61
colorectal cancer KRAS_G12V JAK1 147 58 White -1.20 -3.04 0.07 911.36 1.00 1546 145 56 2 TRUE 0.86
non-small cell lung cancer KRAS_G12V JAK1 147 41 White -0.29 -2.02 0.98 1074.03 1.00 2732 145 39 2 TRUE 0.14
uterine cancer KRAS_G12V JAK1 6 12 Asian 0.76 -1.05 2.70 268.20 1.02 60 3 9 3 TRUE 0.35
uterine cancer KRAS_G12V JAK1 44 113 White -0.82 -2.27 0.20 85.46 1.05 677 42 111 2 TRUE 0.65
colorectal cancer KRAS_G12V JAK1 147 58 Race:overall -1.04 -5.27 3.48 1566.81 1.00 1546 145 56 2 TRUE 0.21
non-small cell lung cancer KRAS_G12V JAK1 147 41 Race:overall -0.26 -5.03 4.42 1597.05 1.00 2732 145 39 2 TRUE 0.04
uterine cancer KRAS_G12V JAK1 50 125 Race:overall -0.06 -1.99 2.16 1228.07 1.00 737 45 120 5 TRUE 0.02
uterine cancer KRAS_G12V CCND1 44 55 White -0.15 -1.57 0.99 1462.31 1.00 701 41 52 3 TRUE 0.09
uterine cancer KRAS_G12V CCND1 44 55 Race:overall -0.14 -4.80 4.32 1544.86 1.00 701 41 52 3 TRUE 0.02
colorectal cancer KRAS_G12V ARID2 148 89 White -0.36 -1.31 0.46 1412.69 1.00 1520 142 83 6 FALSE 0.36
non-small cell lung cancer KRAS_G12V ARID2 147 145 White -0.83 -2.10 0.12 1467.52 1.00 2639 143 141 4 FALSE 0.86
uterine cancer KRAS_G12V ARID2 44 63 White -1.70 -4.52 0.11 1421.82 1.00 710 43 62 1 FALSE 0.81
colorectal cancer KRAS_G12V ARID2 148 89 Race:overall -0.41 -4.34 3.91 1438.91 1.00 1520 142 83 6 FALSE 0.08
non-small cell lung cancer KRAS_G12V ARID2 150 162 Race:overall -1.05 -3.95 1.42 1435.72 1.00 2951 146 158 4 FALSE 0.36
uterine cancer KRAS_G12V ARID2 44 63 Race:overall -1.38 -6.22 3.45 1463.54 1.00 710 43 62 1 FALSE 0.26
colorectal cancer KRAS_G12V SOX17 147 80 White -0.70 -1.87 0.26 897.48 1.00 1525 143 76 4 FALSE 0.69
non-small cell lung cancer KRAS_G12V SOX17 147 51 White 0.36 -0.82 1.36 925.15 1.00 2724 143 47 4 FALSE 0.28
uterine cancer KRAS_G12V SOX17 44 41 White 0.19 -1.28 1.35 1405.35 1.00 715 41 38 3 FALSE 0.11
colorectal cancer KRAS_G12V SOX17 147 80 Race:overall -0.61 -5.24 3.68 1385.63 1.00 1525 143 76 4 FALSE 0.12
non-small cell lung cancer KRAS_G12V SOX17 147 51 Race:overall 0.31 -4.48 4.96 1368.60 1.00 2724 143 47 4 FALSE 0.05
uterine cancer KRAS_G12V SOX17 44 41 Race:overall 0.19 -4.53 4.86 1507.07 1.00 715 41 38 3 FALSE 0.03
colorectal cancer KRAS_G12V MTOR 17 12 Black -0.80 -3.83 0.43 599.90 1.00 121 17 12 0 TRUE 0.33
colorectal cancer KRAS_G12V MTOR 147 111 White -0.34 -1.25 0.42 152.67 1.02 1508 139 103 8 TRUE 0.37
non-small cell lung cancer KRAS_G12V MTOR 147 92 White -0.60 -2.00 0.45 580.32 1.00 2683 144 89 3 TRUE 0.47
uterine cancer KRAS_G12V MTOR 45 76 White -0.55 -2.04 0.59 1349.69 1.00 694 42 73 3 TRUE 0.38
colorectal cancer KRAS_G12V MTOR 164 123 Race:overall -0.55 -2.42 0.58 375.80 1.01 1629 156 115 8 TRUE 0.32
non-small cell lung cancer KRAS_G12V MTOR 147 92 Race:overall -0.58 -4.91 3.64 1388.09 1.00 2683 144 89 3 TRUE 0.12
uterine cancer KRAS_G12V MTOR 45 76 Race:overall -0.54 -4.84 4.17 1136.54 1.00 694 42 73 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V RFWD2 147 50 White -5.88 -15.04 -0.72 226.82 1.01 2720 147 50 0 FALSE 0.77
non-small cell lung cancer KRAS_G12V RFWD2 147 50 Race:overall -4.52 -12.46 2.48 148.09 1.01 2720 147 50 0 FALSE 0.63
colorectal cancer KRAS_G12V IRS1 147 81 White -0.44 -1.41 0.42 143.83 1.04 1528 142 76 5 FALSE 0.48
non-small cell lung cancer KRAS_G12V IRS1 147 58 White -1.61 -4.34 0.22 1239.37 1.00 2715 146 57 1 FALSE 0.78
colorectal cancer KRAS_G12V IRS1 147 81 Race:overall -0.44 -4.66 3.88 1677.90 1.00 1528 142 76 5 FALSE 0.09
non-small cell lung cancer KRAS_G12V IRS1 147 58 Race:overall -1.26 -5.93 3.85 1368.09 1.00 2715 146 57 1 FALSE 0.23
colorectal cancer KRAS_G12V NOTCH1 16 13 Asian -1.37 -2.34 -0.38 194.03 1.03 153 16 13 0 TRUE 2.24
colorectal cancer KRAS_G12V NOTCH1 17 13 Black -1.39 -2.31 -0.46 278.99 1.02 128 17 13 0 TRUE 2.24
colorectal cancer KRAS_G12V NOTCH1 9 11 Unknown -1.38 -2.35 -0.41 305.14 1.02 110 9 11 0 TRUE 2.21
colorectal cancer KRAS_G12V NOTCH1 167 133 White -1.34 -2.20 -0.42 121.80 1.04 1667 162 128 5 TRUE 2.40
non-small cell lung cancer KRAS_G12V NOTCH1 9 11 Black -1.08 -3.53 0.52 1206.19 1.00 179 9 11 0 TRUE 0.51
non-small cell lung cancer KRAS_G12V NOTCH1 152 108 White -0.89 -2.38 0.18 609.96 1.00 2758 149 105 3 TRUE 0.77
uterine cancer KRAS_G12V NOTCH1 6 15 Asian -2.30 -5.83 0.03 859.20 1.00 75 6 15 0 TRUE 0.90
uterine cancer KRAS_G12V NOTCH1 50 64 White -2.05 -4.73 -0.16 692.23 1.01 780 49 63 1 TRUE 1.10
colorectal cancer KRAS_G12V NOTCH1 209 170 Race:overall -1.37 -2.21 -0.46 176.94 1.03 2058 204 165 5 TRUE 2.46
non-small cell lung cancer KRAS_G12V NOTCH1 161 119 Race:overall -0.98 -3.02 0.52 1006.26 1.00 2937 158 116 3 TRUE 0.55
uterine cancer KRAS_G12V NOTCH1 56 79 Race:overall -2.14 -5.10 0.08 784.98 1.00 855 55 78 1 TRUE 0.93
colorectal cancer KRAS_G12V NTRK1 147 46 White -0.93 -2.62 0.36 1470.59 1.00 1552 145 44 2 TRUE 0.66
non-small cell lung cancer KRAS_G12V NTRK1 147 75 White -1.87 -4.66 -0.06 1015.15 1.00 2698 146 74 1 TRUE 0.95
colorectal cancer KRAS_G12V NTRK1 147 46 Race:overall -0.81 -5.31 3.50 1656.42 1.00 1552 145 44 2 TRUE 0.16
non-small cell lung cancer KRAS_G12V NTRK1 147 75 Race:overall -1.49 -6.03 3.49 1333.04 1.00 2698 146 74 1 TRUE 0.29
non-small cell lung cancer KRAS_G12V INPP4A 147 45 White 0.12 -1.20 1.21 914.68 1.00 2729 144 42 3 FALSE 0.07
uterine cancer KRAS_G12V INPP4A 44 52 White -5.85 -15.09 -1.01 883.37 1.00 719 44 52 0 FALSE 0.91
non-small cell lung cancer KRAS_G12V INPP4A 147 45 Race:overall 0.12 -3.97 4.84 1331.77 1.00 2729 144 42 3 FALSE 0.02
uterine cancer KRAS_G12V INPP4A 44 52 Race:overall -4.40 -12.05 2.42 647.41 1.00 719 44 52 0 FALSE 0.67
colorectal cancer KRAS_G12V CASP8 147 73 White -6.25 -15.65 -1.58 1188.17 1.00 1529 147 73 0 FALSE 1.00
uterine cancer KRAS_G12V CASP8 44 46 White -1.49 -4.69 0.43 925.05 1.00 715 43 45 1 FALSE 0.62
colorectal cancer KRAS_G12V CASP8 147 73 Race:overall -4.59 -11.72 2.40 1375.29 1.00 1529 147 73 0 FALSE 0.73
uterine cancer KRAS_G12V CASP8 44 46 Race:overall -1.27 -5.82 3.58 1298.99 1.00 715 43 45 1 FALSE 0.24
colorectal cancer KRAS_G12V SETD2 147 89 White -2.55 -5.36 -0.83 1031.87 1.00 1520 146 88 1 FALSE 1.59
non-small cell lung cancer KRAS_G12V SETD2 148 185 White -0.41 -1.26 0.34 1441.49 1.00 2620 141 178 7 FALSE 0.50
uterine cancer KRAS_G12V SETD2 44 70 White -0.93 -2.71 0.42 1295.93 1.00 706 42 68 2 FALSE 0.60
colorectal cancer KRAS_G12V SETD2 147 89 Race:overall -2.08 -6.19 3.22 1257.26 1.00 1520 146 88 1 FALSE 0.45
non-small cell lung cancer KRAS_G12V SETD2 151 205 Race:overall -0.65 -3.42 1.74 1466.11 1.00 2930 144 198 7 FALSE 0.22
uterine cancer KRAS_G12V SETD2 44 70 Race:overall -0.73 -4.75 3.62 1474.78 1.00 706 42 68 2 FALSE 0.14
colorectal cancer KRAS_G12V PBRM1 147 77 White -2.44 -5.27 -0.59 796.79 1.01 1529 146 76 1 TRUE 1.39
non-small cell lung cancer KRAS_G12V PBRM1 149 95 White -0.04 -1.05 0.82 1505.94 1.00 2690 144 90 5 TRUE 0.03
colorectal cancer KRAS_G12V PBRM1 147 77 Race:overall -2.01 -6.17 3.23 883.03 1.00 1529 146 76 1 TRUE 0.41
non-small cell lung cancer KRAS_G12V PBRM1 149 95 Race:overall 0.00 -4.39 4.28 1414.06 1.00 2690 144 90 5 TRUE 0.00
colorectal cancer KRAS_G12V EPHA3 13 11 Asian -0.25 -2.02 0.85 942.11 1.00 129 13 11 0 FALSE 0.13
colorectal cancer KRAS_G12V EPHA3 9 12 Unknown -0.27 -2.34 0.82 990.59 1.00 109 9 12 0 FALSE 0.14
colorectal cancer KRAS_G12V EPHA3 148 81 White 0.14 -0.61 0.82 646.92 1.00 1528 138 71 10 FALSE 0.15
non-small cell lung cancer KRAS_G12V EPHA3 9 19 Black 0.08 -1.09 0.76 22.55 1.08 168 9 19 0 FALSE 0.06
non-small cell lung cancer KRAS_G12V EPHA3 8 13 Unknown 0.09 -1.15 0.78 26.55 1.07 155 8 13 0 FALSE 0.06
non-small cell lung cancer KRAS_G12V EPHA3 147 199 White 0.21 -0.47 0.73 18.79 1.09 2601 134 186 13 FALSE 0.26
uterine cancer KRAS_G12V EPHA3 44 67 White -6.30 -15.26 -1.11 798.49 1.00 708 44 67 0 FALSE 0.74
colorectal cancer KRAS_G12V EPHA3 170 104 Race:overall -0.14 -1.51 0.79 843.78 1.00 1766 160 94 10 FALSE 0.09
non-small cell lung cancer KRAS_G12V EPHA3 164 231 Race:overall 0.12 -0.82 0.75 20.27 1.09 2924 151 218 13 FALSE 0.10
uterine cancer KRAS_G12V EPHA3 44 67 Race:overall -4.64 -12.15 2.57 1131.67 1.00 708 44 67 0 FALSE 0.71
colorectal cancer KRAS_G12V KIT 166 38 White -1.74 -4.48 0.01 1246.13 1.00 1730 165 37 1 TRUE 0.86
non-small cell lung cancer KRAS_G12V KIT 152 69 White 0.25 -0.66 1.14 349.64 1.00 2793 147 64 5 TRUE 0.24
colorectal cancer KRAS_G12V KIT 166 38 Race:overall -1.45 -6.00 3.32 1449.88 1.00 1730 165 37 1 TRUE 0.29
non-small cell lung cancer KRAS_G12V KIT 152 69 Race:overall 0.26 -3.49 4.09 1326.42 1.00 2793 147 64 5 TRUE 0.05
colorectal cancer KRAS_G12V KDR 166 55 White -0.64 -2.02 0.47 1007.57 1.00 1719 163 52 3 TRUE 0.50
non-small cell lung cancer KRAS_G12V KDR 9 11 Black -0.33 -2.74 0.96 1336.74 1.00 180 9 11 0 TRUE 0.11
non-small cell lung cancer KRAS_G12V KDR 152 121 White -0.01 -0.88 0.73 1227.64 1.00 2748 145 114 7 TRUE 0.01
colorectal cancer KRAS_G12V KDR 166 55 Race:overall -0.53 -4.25 3.68 1407.90 1.00 1719 163 52 3 TRUE 0.11
non-small cell lung cancer KRAS_G12V KDR 161 132 Race:overall -0.18 -1.87 1.00 1419.63 1.00 2928 154 125 7 TRUE 0.08
colorectal cancer KRAS_G12V RICTOR 147 60 White -0.75 -2.17 0.35 1400.77 1.00 1546 144 57 3 FALSE 0.62
non-small cell lung cancer KRAS_G12V RICTOR 147 58 White -1.59 -4.46 0.25 240.89 1.02 2716 146 57 1 FALSE 0.68
uterine cancer KRAS_G12V RICTOR 44 47 White -1.47 -4.28 0.38 1375.35 1.00 720 43 46 1 FALSE 0.66
colorectal cancer KRAS_G12V RICTOR 147 60 Race:overall -0.56 -4.93 4.53 1516.40 1.00 1546 144 57 3 FALSE 0.10
non-small cell lung cancer KRAS_G12V RICTOR 147 58 Race:overall -1.33 -5.76 3.53 903.51 1.00 2716 146 57 1 FALSE 0.25
uterine cancer KRAS_G12V RICTOR 44 47 Race:overall -1.17 -6.01 3.74 1361.83 1.00 720 43 46 1 FALSE 0.21
colorectal cancer KRAS_G12V RAD50 147 42 White -1.80 -4.65 0.05 1522.47 1.00 1558 146 41 1 FALSE 0.88
colorectal cancer KRAS_G12V RAD50 147 42 Race:overall -1.67 -6.35 3.09 1326.14 1.00 1558 146 41 1 FALSE 0.34
colorectal cancer KRAS_G12V CSF1R 166 41 White -0.78 -2.56 0.58 1259.99 1.00 1732 164 39 2 TRUE 0.49
non-small cell lung cancer KRAS_G12V CSF1R 152 59 White 0.70 -0.27 1.57 1078.04 1.00 2806 146 53 6 TRUE 0.87
colorectal cancer KRAS_G12V CSF1R 166 41 Race:overall -0.66 -5.15 4.04 1304.06 1.00 1732 164 39 2 TRUE 0.12
non-small cell lung cancer KRAS_G12V CSF1R 152 59 Race:overall 0.61 -3.43 4.70 1383.59 1.00 2806 146 53 6 TRUE 0.12
non-small cell lung cancer KRAS_G12V PARK2 147 59 White -0.64 -2.56 0.72 1488.41 1.00 2713 145 57 2 FALSE 0.36
non-small cell lung cancer KRAS_G12V PARK2 147 59 Race:overall -0.56 -5.01 3.98 1516.93 1.00 2713 145 57 2 FALSE 0.10
non-small cell lung cancer KRAS_G12V NTRK2 147 56 White -0.06 -1.45 1.00 127.32 1.02 2720 144 53 3 FALSE 0.03
non-small cell lung cancer KRAS_G12V NTRK2 147 56 Race:overall -0.03 -4.61 4.65 913.00 1.00 2720 144 53 3 FALSE 0.01
colorectal cancer KRAS_G12V PTCH1 147 115 White -0.80 -1.94 0.08 772.39 1.00 1508 142 110 5 TRUE 0.95
non-small cell lung cancer KRAS_G12V PTCH1 147 46 White -0.43 -2.20 1.00 1293.61 1.00 2726 145 44 2 TRUE 0.22
uterine cancer KRAS_G12V PTCH1 44 58 White -5.69 -15.12 -0.94 368.44 1.00 708 44 58 0 TRUE 0.86
colorectal cancer KRAS_G12V PTCH1 147 115 Race:overall -0.70 -4.98 3.70 1439.67 1.00 1508 142 110 5 TRUE 0.14
non-small cell lung cancer KRAS_G12V PTCH1 147 46 Race:overall -0.31 -4.66 3.92 1517.08 1.00 2726 145 44 2 TRUE 0.06
uterine cancer KRAS_G12V PTCH1 44 58 Race:overall -4.17 -11.67 3.01 334.39 1.01 708 44 58 0 TRUE 0.59
colorectal cancer KRAS_G12V TET1 147 76 White -2.39 -5.09 -0.54 1078.34 1.00 1532 146 75 1 FALSE 1.37
non-small cell lung cancer KRAS_G12V TET1 147 101 White 0.09 -0.86 0.86 1517.64 1.00 2681 141 95 6 FALSE 0.08
uterine cancer KRAS_G12V TET1 44 60 White -5.82 -14.71 -0.92 1143.75 1.00 712 44 60 0 FALSE 0.91
colorectal cancer KRAS_G12V TET1 147 76 Race:overall -2.13 -6.72 3.10 1513.53 1.00 1532 146 75 1 FALSE 0.46
non-small cell lung cancer KRAS_G12V TET1 147 101 Race:overall 0.02 -4.88 4.37 1555.84 1.00 2681 141 95 6 FALSE 0.00
uterine cancer KRAS_G12V TET1 44 60 Race:overall -4.39 -11.79 2.36 993.60 1.00 712 44 60 0 FALSE 0.68
colorectal cancer KRAS_G12V FGFR2 166 38 White -0.78 -2.64 0.57 1215.92 1.00 1731 164 36 2 TRUE 0.47
uterine cancer KRAS_G12V FGFR2 50 83 White -2.05 -4.43 -0.28 1515.95 1.00 753 49 82 1 TRUE 1.18
colorectal cancer KRAS_G12V FGFR2 166 38 Race:overall -0.60 -4.87 4.03 1615.53 1.00 1731 164 36 2 TRUE 0.11
uterine cancer KRAS_G12V FGFR2 50 83 Race:overall -1.67 -6.28 3.57 1619.07 1.00 753 49 82 1 TRUE 0.32
colorectal cancer KRAS_G12V TBX3 147 57 White -0.46 -1.34 0.55 6.49 1.15 1549 143 53 4 FALSE 0.44
non-small cell lung cancer KRAS_G12V TBX3 147 114 White -0.21 -1.27 0.60 636.62 1.01 2670 142 109 5 FALSE 0.18
uterine cancer KRAS_G12V TBX3 44 43 White -5.65 -14.75 -0.60 1303.26 1.00 718 44 43 0 FALSE 0.80
colorectal cancer KRAS_G12V TBX3 147 57 Race:overall -0.48 -4.01 3.94 701.80 1.01 1549 143 53 4 FALSE 0.10
non-small cell lung cancer KRAS_G12V TBX3 147 114 Race:overall -0.12 -4.43 4.82 1238.14 1.00 2670 142 109 5 FALSE 0.02
uterine cancer KRAS_G12V TBX3 44 43 Race:overall -4.14 -11.73 3.05 1398.67 1.00 718 44 43 0 FALSE 0.61
colorectal cancer KRAS_G12V HNF1A 166 40 White -0.81 -2.69 0.46 1091.33 1.00 1728 164 38 2 TRUE 0.53
colorectal cancer KRAS_G12V HNF1A 166 40 Race:overall -0.72 -4.58 3.41 1136.04 1.00 1728 164 38 2 TRUE 0.15
colorectal cancer KRAS_G12V DICER1 13 12 Asian -2.54 -6.57 0.02 1238.62 1.00 128 13 12 0 TRUE 0.80
colorectal cancer KRAS_G12V DICER1 147 49 White -2.20 -5.25 -0.40 1112.76 1.00 1551 146 48 1 TRUE 1.13
non-small cell lung cancer KRAS_G12V DICER1 147 69 White -0.72 -2.57 0.41 21.48 1.06 2709 145 67 2 TRUE 0.46
uterine cancer KRAS_G12V DICER1 45 64 White -0.34 -1.86 0.74 1096.51 1.00 710 42 61 3 TRUE 0.22
colorectal cancer KRAS_G12V DICER1 160 61 Race:overall -2.33 -5.83 0.02 1212.74 1.00 1679 159 60 1 TRUE 0.95
non-small cell lung cancer KRAS_G12V DICER1 147 69 Race:overall -0.66 -5.01 3.46 1245.48 1.01 2709 145 67 2 TRUE 0.14
uterine cancer KRAS_G12V DICER1 45 64 Race:overall -0.38 -4.75 3.94 1430.66 1.00 710 42 61 3 TRUE 0.07
colorectal cancer KRAS_G12V SMAD3 13 14 Asian 0.04 -1.54 1.15 837.84 1.00 125 12 13 1 TRUE 0.02
colorectal cancer KRAS_G12V SMAD3 147 84 White 0.21 -0.53 0.84 644.13 1.01 1531 138 75 9 TRUE 0.25
colorectal cancer KRAS_G12V SMAD3 160 98 Race:overall 0.15 -1.30 1.43 1111.29 1.00 1656 150 88 10 TRUE 0.08
colorectal cancer KRAS_G12V NTRK3 147 60 White -0.72 -2.27 0.30 596.42 1.01 1543 144 57 3 FALSE 0.59
non-small cell lung cancer KRAS_G12V NTRK3 147 171 White -0.96 -2.17 -0.07 1617.47 1.00 2625 143 167 4 FALSE 1.16
colorectal cancer KRAS_G12V NTRK3 147 60 Race:overall -0.56 -4.68 4.12 1481.64 1.00 1543 144 57 3 FALSE 0.10
non-small cell lung cancer KRAS_G12V NTRK3 150 187 Race:overall -1.12 -4.09 1.54 1336.49 1.00 2936 146 183 4 FALSE 0.38
colorectal cancer KRAS_G12V AXIN1 147 57 White -2.11 -4.75 -0.33 1420.40 1.00 1544 146 56 1 FALSE 1.15
colorectal cancer KRAS_G12V AXIN1 147 57 Race:overall -1.79 -6.18 3.11 1530.89 1.00 1544 146 56 1 FALSE 0.37
colorectal cancer KRAS_G12V GRIN2A 13 11 Asian -1.00 -2.39 0.42 498.19 1.01 129 12 10 1 FALSE 0.82
colorectal cancer KRAS_G12V GRIN2A 147 107 White -1.16 -2.35 -0.20 590.65 1.00 1499 144 104 3 FALSE 1.50
non-small cell lung cancer KRAS_G12V GRIN2A 147 171 White 0.25 -0.46 0.86 523.35 1.01 2621 136 160 11 FALSE 0.34
uterine cancer KRAS_G12V GRIN2A 44 65 White -1.78 -4.58 0.06 1508.91 1.00 708 43 64 1 FALSE 0.86
colorectal cancer KRAS_G12V GRIN2A 160 118 Race:overall -1.08 -2.45 0.11 727.28 1.00 1628 156 114 4 FALSE 1.04
non-small cell lung cancer KRAS_G12V GRIN2A 147 171 Race:overall 0.14 -4.33 4.01 1507.01 1.00 2621 136 160 11 FALSE 0.02
uterine cancer KRAS_G12V GRIN2A 44 65 Race:overall -1.42 -5.91 4.07 1573.46 1.00 708 43 64 1 FALSE 0.27
colorectal cancer KRAS_G12V PALB2 147 44 White -5.96 -15.38 -0.96 962.97 1.00 1552 147 44 0 TRUE 0.99
non-small cell lung cancer KRAS_G12V PALB2 147 47 White 0.08 -1.34 1.22 1401.74 1.00 2728 144 44 3 TRUE 0.05
colorectal cancer KRAS_G12V PALB2 147 44 Race:overall -4.52 -11.68 2.31 977.21 1.00 1552 147 44 0 TRUE 0.75
non-small cell lung cancer KRAS_G12V PALB2 147 47 Race:overall 0.03 -4.61 4.22 1556.50 1.00 2728 144 44 3 TRUE 0.01
colorectal cancer KRAS_G12V CTCF 147 71 White -0.91 -2.25 0.16 1426.43 1.00 1536 144 68 3 FALSE 0.86
uterine cancer KRAS_G12V CTCF 44 137 White -0.26 -1.10 0.50 1055.77 1.00 636 38 131 6 FALSE 0.30
colorectal cancer KRAS_G12V CTCF 147 71 Race:overall -0.69 -4.63 3.75 1434.17 1.00 1536 144 68 3 FALSE 0.14
uterine cancer KRAS_G12V CTCF 49 148 Race:overall -0.22 -1.34 0.96 1425.70 1.00 694 42 141 7 FALSE 0.15
colorectal cancer KRAS_G12V CDH1 167 43 White -0.03 -1.21 0.93 1371.17 1.00 1732 163 39 4 TRUE 0.02
colorectal cancer KRAS_G12V CDH1 167 43 Race:overall 0.06 -3.95 4.53 1513.62 1.00 1732 163 39 4 TRUE 0.01
colorectal cancer KRAS_G12V CDK12 147 76 White -0.97 -2.42 0.07 1487.49 1.00 1535 144 73 3 FALSE 0.90
non-small cell lung cancer KRAS_G12V CDK12 147 45 White -5.71 -15.49 -0.68 1220.62 1.00 2725 147 45 0 FALSE 0.77
colorectal cancer KRAS_G12V CDK12 147 76 Race:overall -0.75 -5.07 4.17 1529.83 1.00 1535 144 73 3 FALSE 0.14
non-small cell lung cancer KRAS_G12V CDK12 147 45 Race:overall -3.94 -11.83 3.19 1442.34 1.00 2725 147 45 0 FALSE 0.55
non-small cell lung cancer KRAS_G12V STK11 9 30 Black 0.50 -0.75 1.60 1426.16 1.00 162 7 28 2 TRUE 0.39
non-small cell lung cancer KRAS_G12V STK11 9 15 Unknown 0.72 -0.54 2.00 1505.94 1.00 157 7 13 2 TRUE 0.60
non-small cell lung cancer KRAS_G12V STK11 154 472 White 0.50 0.11 0.87 1345.45 1.00 2430 119 437 35 TRUE 1.93
non-small cell lung cancer KRAS_G12V STK11 175 536 Race:overall 0.51 -0.60 1.49 1572.77 1.00 3082 136 497 39 TRUE 0.49
colorectal cancer KRAS_G12V DNMT1 147 71 White -1.44 -3.21 -0.14 1639.26 1.00 1534 145 69 2 FALSE 1.14
colorectal cancer KRAS_G12V DNMT1 147 71 Race:overall -1.19 -5.49 3.77 1208.35 1.00 1534 145 69 2 FALSE 0.24
colorectal cancer KRAS_G12V BRD4 147 69 White -0.53 -1.66 0.42 1081.41 1.00 1533 143 65 4 FALSE 0.49
non-small cell lung cancer KRAS_G12V BRD4 147 40 White -5.83 -16.43 -0.57 1334.50 1.00 2732 147 40 0 FALSE 0.72
uterine cancer KRAS_G12V BRD4 44 56 White -5.89 -14.07 -1.10 1277.78 1.00 705 44 56 0 FALSE 0.84
colorectal cancer KRAS_G12V BRD4 147 69 Race:overall -0.50 -4.70 3.75 1487.35 1.00 1533 143 65 4 FALSE 0.10
non-small cell lung cancer KRAS_G12V BRD4 147 40 Race:overall -4.06 -11.53 3.05 1381.39 1.00 2732 147 40 0 FALSE 0.58
uterine cancer KRAS_G12V BRD4 44 56 Race:overall -4.66 -10.80 1.68 200.67 1.03 705 44 56 0 FALSE 0.86
colorectal cancer KRAS_G12V ASXL1 147 85 White -0.75 -1.94 0.23 1196.55 1.00 1521 143 81 4 TRUE 0.72
non-small cell lung cancer KRAS_G12V ASXL1 147 74 White 0.46 -0.49 1.22 277.67 1.00 2716 141 68 6 TRUE 0.48
uterine cancer KRAS_G12V ASXL1 44 49 White -5.69 -13.86 -0.77 1230.63 1.00 716 44 49 0 TRUE 0.80
colorectal cancer KRAS_G12V ASXL1 147 85 Race:overall -0.68 -5.06 4.00 1611.40 1.00 1521 143 81 4 TRUE 0.13
non-small cell lung cancer KRAS_G12V ASXL1 147 74 Race:overall 0.39 -4.08 4.27 1561.47 1.00 2716 141 68 6 TRUE 0.07
uterine cancer KRAS_G12V ASXL1 44 49 Race:overall -4.31 -11.71 2.62 1372.04 1.00 716 44 49 0 TRUE 0.67
colorectal cancer KRAS_G12V EP300 147 107 White -1.01 -2.12 -0.09 1454.13 1.00 1511 143 103 4 TRUE 1.24
non-small cell lung cancer KRAS_G12V EP300 148 91 White -0.60 -1.98 0.50 1032.24 1.00 2691 145 88 3 TRUE 0.46
uterine cancer KRAS_G12V EP300 45 81 White 0.08 -0.94 0.98 1282.83 1.00 694 40 76 5 TRUE 0.06
colorectal cancer KRAS_G12V EP300 147 107 Race:overall -0.76 -4.98 3.90 1438.83 1.00 1511 143 103 4 TRUE 0.15
non-small cell lung cancer KRAS_G12V EP300 148 91 Race:overall -0.58 -4.93 3.65 1473.55 1.00 2691 145 88 3 TRUE 0.11
uterine cancer KRAS_G12V EP300 45 81 Race:overall 0.14 -4.29 4.66 1429.08 1.00 694 40 76 5 TRUE 0.02
colorectal cancer KRAS_G12V ERBB4 9 13 Unknown -0.85 -3.97 0.64 1189.81 1.00 110 9 13 0 TRUE 0.32
colorectal cancer KRAS_G12V ERBB4 167 109 White -0.32 -1.15 0.39 1240.83 1.00 1676 159 101 8 TRUE 0.38
non-small cell lung cancer KRAS_G12V ERBB4 9 17 Black -0.25 -1.52 1.06 1442.51 1.00 176 8 16 1 TRUE 0.15
non-small cell lung cancer KRAS_G12V ERBB4 153 160 White -0.36 -1.22 0.40 845.75 1.00 2726 147 154 6 TRUE 0.43
colorectal cancer KRAS_G12V ERBB4 176 122 Race:overall -0.56 -2.77 0.82 1199.97 1.00 1786 168 114 8 TRUE 0.27
non-small cell lung cancer KRAS_G12V ERBB4 162 177 Race:overall -0.32 -1.66 0.87 1449.00 1.00 2902 155 170 7 TRUE 0.20
colorectal cancer KRAS_G12V MDC1 147 51 White -1.98 -4.93 -0.20 1329.99 1.00 1550 146 50 1 FALSE 1.00
non-small cell lung cancer KRAS_G12V MDC1 8 13 Unknown -0.93 -4.94 1.17 1413.93 1.00 158 8 13 0 FALSE 0.27
non-small cell lung cancer KRAS_G12V MDC1 148 73 White -0.18 -1.39 0.78 1613.44 1.00 2706 144 69 4 FALSE 0.12
colorectal cancer KRAS_G12V MDC1 147 51 Race:overall -1.63 -6.21 3.17 1259.68 1.00 1550 146 50 1 FALSE 0.33
non-small cell lung cancer KRAS_G12V MDC1 156 86 Race:overall -0.47 -3.13 1.61 1308.44 1.00 2864 152 82 4 FALSE 0.17
colorectal cancer KRAS_G12V RECQL4 147 64 White -2.20 -4.87 -0.44 1179.20 1.00 1538 146 63 1 TRUE 1.29
non-small cell lung cancer KRAS_G12V RECQL4 147 50 White -0.49 -2.19 0.82 1459.35 1.00 2724 145 48 2 TRUE 0.28
colorectal cancer KRAS_G12V RECQL4 147 64 Race:overall -1.80 -6.11 3.37 1343.84 1.00 1538 146 63 1 TRUE 0.36
non-small cell lung cancer KRAS_G12V RECQL4 147 50 Race:overall -0.41 -4.73 4.08 1290.28 1.00 2724 145 48 2 TRUE 0.07
colorectal cancer KRAS_G12V MED12 147 95 White -0.39 -1.38 0.42 1283.14 1.00 1520 141 89 6 TRUE 0.42
non-small cell lung cancer KRAS_G12V MED12 147 146 White -0.75 -1.90 0.21 1443.07 1.00 2640 143 142 4 TRUE 0.77
uterine cancer KRAS_G12V MED12 44 107 White -0.87 -2.16 0.16 1312.72 1.00 675 42 105 2 TRUE 0.81
colorectal cancer KRAS_G12V MED12 147 95 Race:overall -0.40 -4.55 3.97 1319.29 1.00 1520 141 89 6 TRUE 0.08
non-small cell lung cancer KRAS_G12V MED12 147 146 Race:overall -0.62 -4.83 4.18 1615.68 1.00 2640 143 142 4 TRUE 0.11
uterine cancer KRAS_G12V MED12 50 131 Race:overall -0.54 -2.10 0.96 1379.18 1.00 818 46 127 4 TRUE 0.32
colorectal cancer KRAS_G12V ERCC5 147 46 White -0.97 -2.67 0.41 1431.22 1.00 1551 145 44 2 TRUE 0.66
non-small cell lung cancer KRAS_G12V ERCC5 147 57 White -5.87 -14.96 -0.80 335.63 1.01 2716 147 57 0 TRUE 0.89
uterine cancer KRAS_G12V ERCC5 44 41 White -1.28 -4.00 0.50 1314.91 1.00 723 43 40 1 TRUE 0.57
colorectal cancer KRAS_G12V ERCC5 147 46 Race:overall -0.68 -4.95 4.67 1455.38 1.00 1551 145 44 2 TRUE 0.12
non-small cell lung cancer KRAS_G12V ERCC5 147 57 Race:overall -4.39 -11.87 3.11 253.69 1.01 2716 147 57 0 TRUE 0.63
uterine cancer KRAS_G12V ERCC5 44 41 Race:overall -1.06 -5.71 3.96 1565.66 1.00 723 43 40 1 TRUE 0.19
colorectal cancer KRAS_G12V PIK3CD 147 58 White -2.07 -4.60 -0.33 1399.23 1.00 1542 146 57 1 FALSE 1.21
colorectal cancer KRAS_G12V PIK3CD 147 58 Race:overall -1.75 -5.93 2.94 1421.51 1.00 1542 146 57 1 FALSE 0.37
colorectal cancer KRAS_G12V BRCA1 147 56 White -1.13 -2.80 0.11 799.63 1.00 1546 145 54 2 TRUE 0.87
non-small cell lung cancer KRAS_G12V BRCA1 147 79 White -0.42 -1.71 0.62 959.06 1.00 2698 144 76 3 TRUE 0.31
colorectal cancer KRAS_G12V BRCA1 147 56 Race:overall -0.96 -5.46 3.80 1648.15 1.00 1546 145 54 2 TRUE 0.18
non-small cell lung cancer KRAS_G12V BRCA1 147 79 Race:overall -0.38 -4.64 3.94 1373.47 1.00 2698 144 76 3 TRUE 0.07
colorectal cancer KRAS_G12V RBM10 147 54 White -1.10 -2.90 0.14 145.19 1.01 1546 145 52 2 FALSE 0.75
non-small cell lung cancer KRAS_G12V RBM10 9 16 Black 0.55 -0.60 1.80 1295.04 1.00 172 7 14 2 FALSE 0.41
non-small cell lung cancer KRAS_G12V RBM10 8 15 Unknown 0.79 -0.39 2.26 1323.63 1.00 155 5 12 3 FALSE 0.61
non-small cell lung cancer KRAS_G12V RBM10 147 314 White -0.03 -0.55 0.50 1617.05 1.00 2486 133 300 14 FALSE 0.04
uterine cancer KRAS_G12V RBM10 44 46 White -0.50 -2.36 0.91 790.98 1.00 718 42 44 2 FALSE 0.26
colorectal cancer KRAS_G12V RBM10 147 54 Race:overall -1.02 -5.23 3.12 1209.71 1.00 1546 145 52 2 FALSE 0.22
non-small cell lung cancer KRAS_G12V RBM10 167 381 Race:overall 0.36 -0.53 1.37 1473.98 1.00 3105 148 362 19 FALSE 0.33
uterine cancer KRAS_G12V RBM10 44 46 Race:overall -0.44 -4.96 3.85 1226.91 1.01 718 42 44 2 FALSE 0.08
colorectal cancer KRAS_G12V TSC1 147 60 White -0.71 -2.18 0.31 1445.33 1.00 1548 144 57 3 TRUE 0.58
non-small cell lung cancer KRAS_G12V TSC1 147 44 White 0.18 -1.21 1.25 1500.50 1.00 2730 144 41 3 TRUE 0.11
uterine cancer KRAS_G12V TSC1 44 51 White -0.58 -2.58 0.69 530.65 1.01 719 42 49 2 TRUE 0.30
colorectal cancer KRAS_G12V TSC1 147 60 Race:overall -0.61 -4.94 3.64 1278.18 1.00 1548 144 57 3 TRUE 0.12
non-small cell lung cancer KRAS_G12V TSC1 147 44 Race:overall 0.06 -4.25 4.62 1399.46 1.00 2730 144 41 3 TRUE 0.01
uterine cancer KRAS_G12V TSC1 44 51 Race:overall -0.55 -5.04 3.75 1476.62 1.00 719 42 49 2 TRUE 0.10
colorectal cancer KRAS_G12V FLCN 147 45 White -0.91 -2.61 0.42 1433.91 1.00 1555 145 43 2 TRUE 0.58
colorectal cancer KRAS_G12V FLCN 147 45 Race:overall -0.79 -5.17 3.64 1458.55 1.00 1555 145 43 2 TRUE 0.15
colorectal cancer KRAS_G12V NF1 147 113 White -1.91 -3.65 -0.54 772.84 1.00 1510 145 111 2 TRUE 1.75
non-small cell lung cancer KRAS_G12V NF1 9 18 Black -0.64 -2.36 0.63 1399.29 1.00 169 9 18 0 TRUE 0.40
non-small cell lung cancer KRAS_G12V NF1 8 14 Unknown -0.62 -2.30 0.67 1374.69 1.00 153 8 14 0 TRUE 0.41
non-small cell lung cancer KRAS_G12V NF1 148 254 White -0.45 -1.21 0.17 771.78 1.00 2565 139 245 9 TRUE 0.69
uterine cancer KRAS_G12V NF1 44 111 White -6.34 -16.20 -1.77 732.84 1.00 687 44 111 0 TRUE 0.79
colorectal cancer KRAS_G12V NF1 147 113 Race:overall -1.59 -5.37 3.22 1432.78 1.00 1510 145 111 2 TRUE 0.36
non-small cell lung cancer KRAS_G12V NF1 168 307 Race:overall -0.50 -1.78 0.48 1371.70 1.00 3194 158 297 10 TRUE 0.42
uterine cancer KRAS_G12V NF1 44 111 Race:overall -4.45 -11.29 2.41 1208.98 1.00 687 44 111 0 TRUE 0.70
colorectal cancer KRAS_G12V FLT1 147 68 White -2.26 -4.65 -0.47 1106.53 1.00 1538 146 67 1 FALSE 1.40
non-small cell lung cancer KRAS_G12V FLT1 147 118 White 0.28 -0.54 0.96 1500.26 1.00 2671 139 110 8 FALSE 0.34
uterine cancer KRAS_G12V FLT1 44 45 White -5.66 -14.93 -0.83 870.46 1.00 720 44 45 0 FALSE 0.80
colorectal cancer KRAS_G12V FLT1 147 68 Race:overall -1.95 -6.13 2.94 1321.26 1.00 1538 146 67 1 FALSE 0.45
non-small cell lung cancer KRAS_G12V FLT1 147 118 Race:overall 0.16 -4.53 4.15 1448.41 1.00 2671 139 110 8 FALSE 0.03
uterine cancer KRAS_G12V FLT1 44 45 Race:overall -4.14 -11.33 2.56 965.02 1.00 720 44 45 0 FALSE 0.64
colorectal cancer KRAS_G12V RPTOR 147 52 White 0.28 -0.76 1.14 1313.08 1.00 1550 141 46 6 FALSE 0.25
non-small cell lung cancer KRAS_G12V RPTOR 148 58 White 0.51 -0.46 1.34 1097.59 1.00 2718 143 53 5 FALSE 0.55
colorectal cancer KRAS_G12V RPTOR 147 52 Race:overall 0.25 -4.03 4.75 1499.40 1.00 1550 141 46 6 FALSE 0.04
non-small cell lung cancer KRAS_G12V RPTOR 148 58 Race:overall 0.32 -4.28 5.00 1576.08 1.00 2718 143 53 5 FALSE 0.06
colorectal cancer KRAS_G12V RASA1 147 58 White -0.33 -1.49 0.64 1060.45 1.00 1552 143 54 4 FALSE 0.25
non-small cell lung cancer KRAS_G12V RASA1 147 84 White -0.50 -1.84 0.55 1326.13 1.00 2690 144 81 3 FALSE 0.38
uterine cancer KRAS_G12V RASA1 44 81 White -1.38 -3.20 -0.01 1326.48 1.00 704 43 80 1 FALSE 1.01
colorectal cancer KRAS_G12V RASA1 147 58 Race:overall -0.37 -5.08 4.32 1486.37 1.00 1552 143 54 4 FALSE 0.06
non-small cell lung cancer KRAS_G12V RASA1 147 84 Race:overall -0.38 -5.01 4.42 1501.68 1.00 2690 144 81 3 FALSE 0.07
uterine cancer KRAS_G12V RASA1 49 92 Race:overall -1.16 -3.08 0.67 1268.35 1.00 763 47 90 2 FALSE 0.63
colorectal cancer KRAS_G12V EPHA5 13 11 Asian -0.71 -2.02 0.14 74.77 1.03 132 13 11 0 FALSE 0.70
colorectal cancer KRAS_G12V EPHA5 9 12 Unknown -0.72 -2.08 0.10 76.76 1.03 110 9 12 0 FALSE 0.68
colorectal cancer KRAS_G12V EPHA5 147 115 White -0.67 -1.64 -0.03 62.96 1.03 1500 141 109 6 FALSE 0.93
non-small cell lung cancer KRAS_G12V EPHA5 9 18 Black -0.19 -2.13 1.11 1462.65 1.00 170 9 18 0 FALSE 0.09
non-small cell lung cancer KRAS_G12V EPHA5 8 12 Unknown 0.51 -0.82 1.85 1627.01 1.00 157 6 10 2 FALSE 0.34
non-small cell lung cancer KRAS_G12V EPHA5 148 213 White 0.12 -0.51 0.66 1344.61 1.00 2587 136 201 12 FALSE 0.16
uterine cancer KRAS_G12V EPHA5 44 78 White -2.00 -4.68 -0.24 1020.79 1.00 704 43 77 1 FALSE 1.16
colorectal cancer KRAS_G12V EPHA5 169 138 Race:overall -0.70 -1.90 0.02 65.70 1.03 1742 163 132 6 FALSE 0.79
non-small cell lung cancer KRAS_G12V EPHA5 168 255 Race:overall 0.11 -1.12 1.24 1540.92 1.00 3229 154 241 14 FALSE 0.07
uterine cancer KRAS_G12V EPHA5 44 78 Race:overall -1.86 -6.08 2.81 986.88 1.01 704 43 77 1 FALSE 0.41
colorectal cancer KRAS_G12V AR 147 86 White -0.10 -0.97 0.65 1131.08 1.00 1518 140 79 7 TRUE 0.10
non-small cell lung cancer KRAS_G12V AR 9 13 Black 0.19 -1.44 1.64 1408.06 1.01 175 8 12 1 TRUE 0.09
non-small cell lung cancer KRAS_G12V AR 147 80 White 0.13 -0.82 0.98 783.49 1.01 2700 142 75 5 TRUE 0.11
uterine cancer KRAS_G12V AR 44 51 White -1.55 -4.26 0.28 633.34 1.00 712 43 50 1 TRUE 0.71
colorectal cancer KRAS_G12V AR 147 86 Race:overall -0.11 -4.50 3.87 1721.90 1.00 1518 140 79 7 TRUE 0.02
non-small cell lung cancer KRAS_G12V AR 156 93 Race:overall 0.14 -1.34 1.70 1250.87 1.00 2875 150 87 6 TRUE 0.07
uterine cancer KRAS_G12V AR 44 51 Race:overall -1.28 -5.77 3.40 1249.24 1.00 712 43 50 1 TRUE 0.24
colorectal cancer KRAS_G12V GNAS 166 66 White -0.01 -0.99 0.82 1492.35 1.00 1710 160 60 6 TRUE 0.00
pancreatic cancer KRAS_G12V GNAS 323 53 White -0.18 -0.86 0.43 1318.31 1.00 916 311 41 12 TRUE 0.22
colorectal cancer KRAS_G12V GNAS 166 66 Race:overall -0.04 -4.23 4.69 1334.27 1.00 1710 160 60 6 TRUE 0.01
pancreatic cancer KRAS_G12V GNAS 323 53 Race:overall -0.19 -4.36 4.04 1353.14 1.00 916 311 41 12 TRUE 0.03
colorectal cancer KRAS_G12V ASXL2 147 60 White -1.16 -2.90 0.18 1067.17 1.00 1553 145 58 2 FALSE 0.88
non-small cell lung cancer KRAS_G12V ASXL2 147 53 White -5.97 -16.96 -0.84 1285.04 1.00 2720 147 53 0 FALSE 0.70
colorectal cancer KRAS_G12V ASXL2 147 60 Race:overall -0.92 -4.96 4.02 1453.03 1.00 1553 145 58 2 FALSE 0.18
non-small cell lung cancer KRAS_G12V ASXL2 147 53 Race:overall -4.32 -11.90 2.48 1411.46 1.00 2720 147 53 0 FALSE 0.63
colorectal cancer KRAS_G12V SF3B1 147 51 White -1.05 -2.86 0.25 1341.60 1.00 1553 145 49 2 TRUE 0.73
non-small cell lung cancer KRAS_G12V SF3B1 147 71 White 0.29 -0.69 1.14 1278.78 1.00 2707 142 66 5 TRUE 0.26
colorectal cancer KRAS_G12V SF3B1 147 51 Race:overall -0.93 -5.51 3.65 1393.61 1.00 1553 145 49 2 TRUE 0.18
non-small cell lung cancer KRAS_G12V SF3B1 147 71 Race:overall 0.32 -3.89 4.79 1571.41 1.00 2707 142 66 5 TRUE 0.06
colorectal cancer KRAS_G12V MLH1 166 49 White -2.00 -4.91 -0.17 1178.13 1.00 1726 165 48 1 TRUE 1.03
colorectal cancer KRAS_G12V MLH1 166 49 Race:overall -1.68 -6.28 3.38 1242.02 1.00 1726 165 48 1 TRUE 0.33
colorectal cancer KRAS_G12V ROS1 13 16 Asian -3.06 -6.58 -0.42 89.87 1.05 126 13 16 0 TRUE 1.27
colorectal cancer KRAS_G12V ROS1 147 71 White -2.80 -5.31 -0.81 27.16 1.13 1529 146 70 1 TRUE 1.54
non-small cell lung cancer KRAS_G12V ROS1 147 93 White -6.18 -16.20 -1.21 1236.44 1.00 2682 147 93 0 TRUE 0.87
uterine cancer KRAS_G12V ROS1 44 79 White -1.06 -2.86 0.28 943.38 1.00 713 42 77 2 TRUE 0.70
colorectal cancer KRAS_G12V ROS1 160 87 Race:overall -2.85 -5.83 -0.24 37.01 1.09 1655 159 86 1 TRUE 1.29
non-small cell lung cancer KRAS_G12V ROS1 147 93 Race:overall -4.58 -11.77 2.26 1209.30 1.00 2682 147 93 0 TRUE 0.75
uterine cancer KRAS_G12V ROS1 44 79 Race:overall -0.95 -5.36 3.93 1403.74 1.00 713 42 77 2 TRUE 0.18
colorectal cancer KRAS_G12V PIK3R2 147 36 White -0.18 -1.64 0.95 1406.06 1.00 1561 144 33 3 FALSE 0.10
colorectal cancer KRAS_G12V PIK3R2 147 36 Race:overall -0.17 -4.48 4.25 1519.66 1.00 1561 144 33 3 FALSE 0.03
colorectal cancer KRAS_G12V FLT3 166 36 White -0.18 -1.70 0.98 1303.95 1.00 1736 163 33 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V FLT3 152 62 White 0.12 -1.03 1.08 316.53 1.02 2802 148 58 4 TRUE 0.08
uterine cancer KRAS_G12V FLT3 50 53 White -5.82 -14.88 -0.91 1235.02 1.00 792 50 53 0 TRUE 0.91
colorectal cancer KRAS_G12V FLT3 166 36 Race:overall -0.14 -4.46 4.30 1506.75 1.00 1736 163 33 3 TRUE 0.02
non-small cell lung cancer KRAS_G12V FLT3 152 62 Race:overall 0.09 -4.36 4.80 1311.54 1.00 2802 148 58 4 TRUE 0.02
uterine cancer KRAS_G12V FLT3 50 53 Race:overall -4.21 -11.65 2.63 1431.62 1.00 792 50 53 0 TRUE 0.64
colorectal cancer KRAS_G12V MSH2 148 63 White -0.16 -1.27 0.74 1415.61 1.00 1551 143 58 5 TRUE 0.12
non-small cell lung cancer KRAS_G12V MSH2 147 45 White -0.36 -2.18 1.04 1315.36 1.00 2731 145 43 2 TRUE 0.18
uterine cancer KRAS_G12V MSH2 44 51 White -5.74 -15.34 -0.87 1330.11 1.00 716 44 51 0 TRUE 0.86
colorectal cancer KRAS_G12V MSH2 148 63 Race:overall -0.10 -4.05 4.02 1405.13 1.00 1551 143 58 5 TRUE 0.02
non-small cell lung cancer KRAS_G12V MSH2 147 45 Race:overall -0.30 -5.02 3.98 1525.45 1.00 2731 145 43 2 TRUE 0.05
uterine cancer KRAS_G12V MSH2 44 51 Race:overall -4.41 -11.90 1.73 1042.99 1.00 716 44 51 0 TRUE 0.69
non-small cell lung cancer KRAS_G12V DIS3 147 53 White -0.03 -1.36 1.07 1120.35 1.00 2721 144 50 3 FALSE 0.02
non-small cell lung cancer KRAS_G12V DIS3 147 53 Race:overall -0.06 -4.62 4.25 1492.60 1.00 2721 144 50 3 FALSE 0.01
colorectal cancer KRAS_G12V AXL 147 67 White -1.19 -2.94 -0.07 15.07 1.12 1538 145 65 2 FALSE 0.82
colorectal cancer KRAS_G12V AXL 147 67 Race:overall -0.98 -4.81 2.95 401.18 1.02 1538 145 65 2 FALSE 0.22
pancreatic cancer KRAS_G12V DAXX 313 46 White -3.16 -6.06 -1.41 1069.97 1.00 875 312 45 1 TRUE 2.10
pancreatic cancer KRAS_G12V DAXX 313 46 Race:overall -2.62 -6.89 2.87 1359.23 1.00 875 312 45 1 TRUE 0.60
colorectal cancer KRAS_G12V PIK3CG 147 89 White 0.02 -0.80 0.73 1349.74 1.00 1521 139 81 8 FALSE 0.02
non-small cell lung cancer KRAS_G12V PIK3CG 9 12 Black -0.23 -2.49 0.97 1305.47 1.00 174 9 12 0 FALSE 0.10
non-small cell lung cancer KRAS_G12V PIK3CG 147 151 White 0.06 -0.67 0.75 900.17 1.00 2643 138 142 9 FALSE 0.06
uterine cancer KRAS_G12V PIK3CG 44 43 White -1.39 -4.12 0.48 1349.15 1.00 721 43 42 1 FALSE 0.60
colorectal cancer KRAS_G12V PIK3CG 147 89 Race:overall -0.01 -4.85 4.33 1391.30 1.00 1521 139 81 8 FALSE 0.00
non-small cell lung cancer KRAS_G12V PIK3CG 156 163 Race:overall -0.06 -1.59 1.09 1296.17 1.00 2817 147 154 9 FALSE 0.03
uterine cancer KRAS_G12V PIK3CG 44 43 Race:overall -1.18 -6.05 3.68 1468.99 1.00 721 43 42 1 FALSE 0.21
colorectal cancer KRAS_G12V MAP2K4 147 53 White -1.90 -4.67 -0.12 116.06 1.04 1543 146 52 1 TRUE 1.00
colorectal cancer KRAS_G12V MAP2K4 147 53 Race:overall -1.60 -5.93 3.66 1227.49 1.01 1543 146 52 1 TRUE 0.32
colorectal cancer KRAS_G12V EGFR 166 59 White -0.72 -2.17 0.34 1288.88 1.01 1716 163 56 3 TRUE 0.61
non-small cell lung cancer KRAS_G12V EGFR 9 69 Black -3.79 -6.02 -1.88 1386.91 1.00 136 9 69 0 TRUE 3.44
non-small cell lung cancer KRAS_G12V EGFR 9 52 Unknown -3.78 -6.24 -1.89 1434.27 1.00 124 9 52 0 TRUE 3.40
non-small cell lung cancer KRAS_G12V EGFR 152 694 White -3.57 -5.21 -2.21 1423.89 1.00 2293 150 692 2 TRUE 5.23
colorectal cancer KRAS_G12V EGFR 166 59 Race:overall -0.68 -5.05 3.52 1438.70 1.00 1716 163 56 3 TRUE 0.13
non-small cell lung cancer KRAS_G12V EGFR 176 1038 Race:overall -3.72 -5.61 -2.16 1395.10 1.00 2770 174 1036 2 TRUE 4.49
colorectal cancer KRAS_G12V ARID1B 147 121 White -2.00 -3.77 -0.73 1226.29 1.00 1494 145 119 2 TRUE 1.99
non-small cell lung cancer KRAS_G12V ARID1B 148 82 White 0.05 -1.01 0.94 1449.44 1.00 2695 143 77 5 TRUE 0.04
uterine cancer KRAS_G12V ARID1B 44 89 White -1.21 -3.03 0.11 1392.91 1.00 685 42 87 2 TRUE 0.89
colorectal cancer KRAS_G12V ARID1B 147 121 Race:overall -1.69 -5.68 3.20 1480.50 1.00 1494 145 119 2 TRUE 0.37
non-small cell lung cancer KRAS_G12V ARID1B 151 94 Race:overall -0.31 -3.49 2.06 1344.43 1.00 3011 146 89 5 TRUE 0.09
uterine cancer KRAS_G12V ARID1B 44 89 Race:overall -1.00 -5.22 3.82 1570.35 1.00 685 42 87 2 TRUE 0.20
non-small cell lung cancer KRAS_G12V INSR 147 48 White -1.98 -3.89 0.24 3.38 1.33 2726 146 47 1 FALSE 0.93
uterine cancer KRAS_G12V INSR 44 42 White -1.33 -3.98 0.44 1321.07 1.00 723 43 41 1 FALSE 0.59
non-small cell lung cancer KRAS_G12V INSR 147 48 Race:overall -1.80 -5.37 2.84 7.97 1.12 2726 146 47 1 FALSE 0.42
uterine cancer KRAS_G12V INSR 44 42 Race:overall -1.17 -5.80 3.46 1312.71 1.00 723 43 41 1 FALSE 0.22
non-small cell lung cancer KRAS_G12V NKX2-1 150 58 White 1.47 0.74 2.14 594.80 1.01 2728 139 47 11 TRUE 4.30
non-small cell lung cancer KRAS_G12V NKX2-1 150 58 Race:overall 1.21 -3.59 5.38 1441.09 1.00 2728 139 47 11 TRUE 0.25
colorectal cancer KRAS_G12V ARID5B 147 53 White -2.02 -4.88 -0.19 1153.56 1.00 1555 146 52 1 FALSE 1.09
uterine cancer KRAS_G12V ARID5B 44 60 White -0.72 -2.52 0.58 818.61 1.00 708 42 58 2 FALSE 0.43
colorectal cancer KRAS_G12V ARID5B 147 53 Race:overall -1.59 -6.05 3.50 1449.83 1.00 1555 146 52 1 FALSE 0.33
uterine cancer KRAS_G12V ARID5B 44 60 Race:overall -0.59 -5.16 4.18 1363.36 1.00 708 42 58 2 FALSE 0.11
non-small cell lung cancer KRAS_G12V WT1 147 60 White -0.67 -2.51 0.61 1403.32 1.00 2715 145 58 2 TRUE 0.40
non-small cell lung cancer KRAS_G12V WT1 147 60 Race:overall -0.56 -4.73 3.79 1400.26 1.00 2715 145 58 2 TRUE 0.10
non-small cell lung cancer KRAS_G12V MET 152 140 White -0.28 -1.20 0.53 1527.12 1.00 2735 146 134 6 TRUE 0.27
uterine cancer KRAS_G12V MET 50 51 White -5.94 -16.27 -0.93 953.14 1.00 794 50 51 0 TRUE 0.80
non-small cell lung cancer KRAS_G12V MET 155 153 Race:overall -0.58 -3.70 2.03 1372.05 1.00 3071 149 147 6 TRUE 0.17
uterine cancer KRAS_G12V MET 50 51 Race:overall -4.38 -11.70 2.38 730.00 1.01 794 50 51 0 TRUE 0.68
non-small cell lung cancer KRAS_G12V PMS1 147 44 White 1.05 0.14 1.89 1277.30 1.00 2733 141 38 6 TRUE 1.63
non-small cell lung cancer KRAS_G12V PMS1 147 44 Race:overall 0.94 -3.23 5.08 1355.19 1.00 2733 141 38 6 TRUE 0.20
pancreatic cancer KRAS_G12V MEN1 313 67 White -3.53 -6.13 -1.82 1490.80 1.00 851 312 66 1 TRUE 2.74
pancreatic cancer KRAS_G12V MEN1 313 67 Race:overall -2.91 -7.34 2.66 1618.37 1.00 851 312 66 1 TRUE 0.67
non-small cell lung cancer KRAS_G12V PIK3C3 147 62 White -0.19 -1.57 0.89 1239.26 1.00 2713 144 59 3 FALSE 0.12
non-small cell lung cancer KRAS_G12V PIK3C3 147 62 Race:overall -0.14 -4.38 4.18 1321.03 1.00 2713 144 59 3 FALSE 0.02
colorectal cancer KRAS_G12V BRAF 16 15 Asian -2.31 -3.83 -1.20 1186.13 1.00 148 16 15 0 TRUE 3.41
colorectal cancer KRAS_G12V BRAF 17 14 Black -2.31 -3.88 -1.21 1152.22 1.00 122 17 14 0 TRUE 3.32
colorectal cancer KRAS_G12V BRAF 9 13 Unknown -2.31 -3.84 -1.22 1138.67 1.00 107 9 13 0 TRUE 3.29
colorectal cancer KRAS_G12V BRAF 166 207 White -2.29 -3.77 -1.26 1147.22 1.00 1572 163 204 3 TRUE 3.56
non-small cell lung cancer KRAS_G12V BRAF 152 167 White -0.27 -1.11 0.49 1235.51 1.00 2700 145 160 7 TRUE 0.29
colorectal cancer KRAS_G12V BRAF 208 249 Race:overall -2.31 -3.84 -1.24 1150.96 1.00 1949 205 246 3 TRUE 3.47
non-small cell lung cancer KRAS_G12V BRAF 152 167 Race:overall -0.29 -5.11 4.33 1400.80 1.00 2700 145 160 7 TRUE 0.05
colorectal cancer KRAS_G12V B2M 13 16 Asian -2.05 -3.91 -0.56 608.42 1.00 128 13 16 0 FALSE 1.66
colorectal cancer KRAS_G12V B2M 9 11 Unknown -1.87 -3.76 -0.25 464.97 1.00 113 8 10 1 FALSE 1.38
colorectal cancer KRAS_G12V B2M 147 102 White -2.05 -3.78 -0.71 451.36 1.00 1530 146 101 1 FALSE 2.00
colorectal cancer KRAS_G12V B2M 169 129 Race:overall -1.99 -3.79 -0.57 448.79 1.00 1771 167 127 2 FALSE 1.78
colorectal cancer KRAS_G12V TGFBR1 147 33 White -1.51 -4.07 0.26 1269.44 1.00 1565 146 32 1 FALSE 0.73
non-small cell lung cancer KRAS_G12V TGFBR1 147 37 White -1.13 -3.99 0.68 1118.72 1.00 2734 146 36 1 FALSE 0.45
colorectal cancer KRAS_G12V TGFBR1 147 33 Race:overall -1.28 -5.68 3.78 1248.54 1.00 1565 146 32 1 FALSE 0.25
non-small cell lung cancer KRAS_G12V TGFBR1 147 37 Race:overall -0.96 -5.58 3.60 1470.23 1.00 2734 146 36 1 FALSE 0.17
colorectal cancer KRAS_G12V TET2 147 67 White -1.34 -3.26 0.04 1264.29 1.00 1540 145 65 2 TRUE 1.00
non-small cell lung cancer KRAS_G12V TET2 147 66 White -1.77 -4.22 0.10 91.67 1.04 2710 146 65 1 TRUE 0.87
uterine cancer KRAS_G12V TET2 44 55 White -1.58 -4.25 0.08 1417.27 1.00 710 43 54 1 TRUE 0.81
colorectal cancer KRAS_G12V TET2 147 67 Race:overall -1.07 -5.26 3.50 1352.34 1.00 1540 145 65 2 TRUE 0.22
non-small cell lung cancer KRAS_G12V TET2 147 66 Race:overall -1.52 -5.69 3.80 394.06 1.01 2710 146 65 1 TRUE 0.30
uterine cancer KRAS_G12V TET2 44 55 Race:overall -1.41 -5.58 3.31 1339.87 1.00 710 43 54 1 TRUE 0.29
colorectal cancer KRAS_G12V PDGFRB 147 38 White -1.68 -4.29 0.16 1221.17 1.00 1557 146 37 1 TRUE 0.82
non-small cell lung cancer KRAS_G12V PDGFRB 148 82 White 0.53 -0.35 1.24 597.15 1.00 2701 141 75 7 TRUE 0.71
colorectal cancer KRAS_G12V PDGFRB 147 38 Race:overall -1.38 -5.76 3.40 1383.15 1.00 1557 146 37 1 TRUE 0.27
non-small cell lung cancer KRAS_G12V PDGFRB 148 82 Race:overall 0.48 -4.12 5.07 1129.44 1.00 2701 141 75 7 TRUE 0.09
colorectal cancer KRAS_G12V CARD11 147 106 White -1.01 -2.18 -0.04 993.30 1.00 1502 143 102 4 FALSE 1.20
non-small cell lung cancer KRAS_G12V CARD11 147 100 White -0.98 -2.61 0.34 14.74 1.12 2679 144 97 3 FALSE 0.60
uterine cancer KRAS_G12V CARD11 44 47 White -6.66 -14.72 -0.77 21.20 1.13 714 44 47 0 FALSE 0.95
colorectal cancer KRAS_G12V CARD11 147 106 Race:overall -0.89 -4.93 3.49 1105.94 1.00 1502 143 102 4 FALSE 0.18
non-small cell lung cancer KRAS_G12V CARD11 147 100 Race:overall -0.91 -4.81 4.12 111.09 1.02 2679 144 97 3 FALSE 0.18
uterine cancer KRAS_G12V CARD11 44 47 Race:overall -5.35 -11.25 2.06 14.40 1.26 714 44 47 0 FALSE 0.71
colorectal cancer KRAS_G12V DNMT3A 147 40 White -0.77 -2.53 0.44 1168.65 1.00 1559 145 38 2 TRUE 0.51
non-small cell lung cancer KRAS_G12V DNMT3A 147 66 White 0.34 -0.71 1.21 1186.18 1.00 2710 142 61 5 TRUE 0.31
colorectal cancer KRAS_G12V DNMT3A 147 40 Race:overall -0.66 -4.88 3.91 1432.51 1.00 1559 145 38 2 TRUE 0.13
non-small cell lung cancer KRAS_G12V DNMT3A 147 66 Race:overall 0.34 -4.27 4.70 1477.53 1.00 2710 142 61 5 TRUE 0.06
colorectal cancer KRAS_G12V MSH6 147 83 White -1.06 -2.40 0.05 1456.30 1.00 1529 144 80 3 TRUE 1.00
uterine cancer KRAS_G12V MSH6 44 72 White -0.92 -2.71 0.37 548.49 1.01 706 42 70 2 TRUE 0.62
colorectal cancer KRAS_G12V MSH6 147 83 Race:overall -0.97 -5.29 3.55 1457.19 1.00 1529 144 80 3 TRUE 0.19
uterine cancer KRAS_G12V MSH6 44 72 Race:overall -0.71 -5.25 3.92 1508.60 1.00 706 42 70 2 TRUE 0.13
non-small cell lung cancer KRAS_G12V MAX 147 46 White 0.99 -0.01 1.82 1231.10 1.00 2731 141 40 6 FALSE 1.45
non-small cell lung cancer KRAS_G12V MAX 147 46 Race:overall 0.79 -4.12 5.53 1361.81 1.00 2731 141 40 6 FALSE 0.15
non-small cell lung cancer KRAS_G12V INPP4B 147 111 White 0.00 -0.89 0.83 1312.49 1.00 2674 141 105 6 FALSE 0.00
non-small cell lung cancer KRAS_G12V INPP4B 147 111 Race:overall 0.05 -4.11 4.85 1284.68 1.00 2674 141 105 6 FALSE 0.01
non-small cell lung cancer KRAS_G12V NFE2L2 147 101 White -0.38 -1.59 0.60 1479.29 1.00 2682 143 97 4 FALSE 0.31
non-small cell lung cancer KRAS_G12V NFE2L2 147 101 Race:overall -0.26 -4.81 3.87 1457.71 1.00 2682 143 97 4 FALSE 0.05
uterine cancer KRAS_G12V SPOP 44 39 White -2.39 -7.24 0.03 1298.44 1.00 715 44 39 0 FALSE 0.64
uterine cancer KRAS_G12V SPOP 49 50 Race:overall -1.57 -4.97 0.99 1512.92 1.00 772 48 49 1 FALSE 0.51
colorectal cancer KRAS_G12V SOX9 13 21 Asian 0.22 -0.44 0.78 1032.91 1.00 121 11 19 2 FALSE 0.33
colorectal cancer KRAS_G12V SOX9 17 15 Black 0.23 -0.38 0.84 939.51 1.00 118 15 13 2 FALSE 0.35
colorectal cancer KRAS_G12V SOX9 149 209 White 0.24 -0.21 0.67 938.86 1.00 1424 127 187 22 FALSE 0.55
colorectal cancer KRAS_G12V SOX9 179 245 Race:overall 0.24 -0.32 0.76 1062.84 1.00 1663 153 219 26 FALSE 0.40
colorectal cancer KRAS_G12V ETV1 147 44 White -0.94 -2.72 0.46 909.03 1.00 1555 145 42 2 TRUE 0.61
colorectal cancer KRAS_G12V ETV1 147 44 Race:overall -0.89 -5.24 3.74 1321.99 1.00 1555 145 42 2 TRUE 0.17
colorectal cancer KRAS_G12V ARAF 148 50 White -1.05 -2.89 0.28 1125.86 1.00 1550 146 48 2 FALSE 0.71
non-small cell lung cancer KRAS_G12V ARAF 147 52 White -1.42 -4.11 0.43 1269.53 1.00 2724 146 51 1 FALSE 0.65
colorectal cancer KRAS_G12V ARAF 148 50 Race:overall -0.76 -5.12 4.27 1426.14 1.00 1550 146 48 2 FALSE 0.14
non-small cell lung cancer KRAS_G12V ARAF 147 52 Race:overall -1.17 -5.88 3.83 1588.11 1.00 2724 146 51 1 FALSE 0.21
non-small cell lung cancer KRAS_G12V JAK2 152 62 White -0.19 -1.52 0.89 1391.45 1.00 2800 149 59 3 TRUE 0.12
non-small cell lung cancer KRAS_G12V JAK2 152 62 Race:overall -0.21 -4.63 3.91 1512.87 1.00 2800 149 59 3 TRUE 0.04
colorectal cancer KRAS_G12V SMAD2 148 74 White 0.36 -0.46 1.04 1524.91 1.00 1538 139 65 9 TRUE 0.49
colorectal cancer KRAS_G12V SMAD2 148 74 Race:overall 0.29 -4.20 4.59 1474.76 1.00 1538 139 65 9 TRUE 0.05
non-small cell lung cancer KRAS_G12V TP63 147 63 White -0.20 -1.51 0.86 1048.50 1.00 2712 144 60 3 FALSE 0.13
non-small cell lung cancer KRAS_G12V TP63 147 63 Race:overall -0.15 -4.57 4.10 1337.34 1.00 2712 144 60 3 FALSE 0.03
colorectal cancer KRAS_G12V JUN 147 41 White -1.78 -4.38 0.01 942.58 1.00 1557 146 40 1 FALSE 0.90
colorectal cancer KRAS_G12V JUN 147 41 Race:overall -1.36 -5.76 3.91 1250.33 1.00 1557 146 40 1 FALSE 0.26
colorectal cancer KRAS_G12V DNMT3B 148 46 White 0.17 -0.84 1.08 1093.74 1.00 1559 143 41 5 FALSE 0.14
colorectal cancer KRAS_G12V DNMT3B 148 46 Race:overall 0.18 -3.90 4.97 1486.65 1.00 1559 143 41 5 FALSE 0.03
non-small cell lung cancer KRAS_G12V MYOD1 147 46 White 0.49 -0.68 1.45 1147.09 1.00 2732 143 42 4 FALSE 0.43
non-small cell lung cancer KRAS_G12V MYOD1 147 46 Race:overall 0.43 -4.09 4.69 1302.94 1.00 2732 143 42 4 FALSE 0.08
colorectal cancer KRAS_G12V FGFR1 166 37 White -1.69 -4.53 0.12 1209.94 1.00 1734 165 36 1 TRUE 0.80
colorectal cancer KRAS_G12V FGFR1 166 37 Race:overall -1.36 -5.79 3.73 1524.83 1.00 1734 165 36 1 TRUE 0.26
colorectal cancer KRAS_G12V MITF 147 42 White -1.73 -4.55 0.07 1392.02 1.00 1552 146 41 1 FALSE 0.84
colorectal cancer KRAS_G12V MITF 147 42 Race:overall -1.40 -6.30 3.69 1562.51 1.00 1552 146 41 1 FALSE 0.27
non-small cell lung cancer KRAS_G12V BTK 147 49 White 0.06 -1.40 1.16 1532.71 1.00 2725 144 46 3 TRUE 0.03
non-small cell lung cancer KRAS_G12V BTK 147 49 Race:overall 0.08 -4.33 4.88 1226.25 1.00 2725 144 46 3 TRUE 0.01
colorectal cancer KRAS_G12V SH2B3 137 41 White -6.29 -18.27 -1.20 570.66 1.00 1409 137 41 0 FALSE 0.80
colorectal cancer KRAS_G12V SH2B3 137 41 Race:overall -4.53 -13.31 2.83 370.07 1.01 1409 137 41 0 FALSE 0.61
colorectal cancer KRAS_G12V GLI1 10 11 Asian -2.49 -5.69 -0.26 904.34 1.00 118 10 11 0 FALSE 1.13
colorectal cancer KRAS_G12V GLI1 137 65 White -2.37 -5.00 -0.68 365.87 1.00 1388 136 64 1 FALSE 1.42
non-small cell lung cancer KRAS_G12V GLI1 137 90 White 0.68 -0.11 1.36 937.55 1.00 2408 128 81 9 FALSE 1.19
uterine cancer KRAS_G12V GLI1 40 44 White -1.39 -4.08 0.32 756.60 1.00 630 39 43 1 FALSE 0.67
colorectal cancer KRAS_G12V GLI1 147 76 Race:overall -2.37 -5.09 -0.21 550.91 1.00 1506 146 75 1 FALSE 1.15
non-small cell lung cancer KRAS_G12V GLI1 137 90 Race:overall 0.55 -3.94 4.36 1382.01 1.00 2408 128 81 9 FALSE 0.11
uterine cancer KRAS_G12V GLI1 40 44 Race:overall -1.13 -5.45 3.77 1328.20 1.01 630 39 43 1 FALSE 0.22
colorectal cancer KRAS_G12V ZFHX3 10 18 Asian -1.21 -2.29 -0.32 786.02 1.00 116 10 18 0 FALSE 1.69
colorectal cancer KRAS_G12V ZFHX3 9 15 Unknown -1.21 -2.28 -0.34 830.93 1.00 101 9 15 0 FALSE 1.65
colorectal cancer KRAS_G12V ZFHX3 139 183 White -1.14 -2.15 -0.40 670.23 1.00 1320 132 176 7 FALSE 2.06
non-small cell lung cancer KRAS_G12V ZFHX3 9 11 Black -0.02 -2.44 1.13 1014.89 1.00 159 9 11 0 FALSE 0.01
non-small cell lung cancer KRAS_G12V ZFHX3 138 136 White 0.28 -0.41 0.90 1290.75 1.00 2361 128 126 10 FALSE 0.41
uterine cancer KRAS_G12V ZFHX3 41 180 White -0.50 -1.38 0.30 1335.65 1.00 561 35 174 6 FALSE 0.60
colorectal cancer KRAS_G12V ZFHX3 158 216 Race:overall -1.19 -2.23 -0.39 783.10 1.00 1537 151 209 7 FALSE 1.90
non-small cell lung cancer KRAS_G12V ZFHX3 147 147 Race:overall 0.15 -1.55 1.31 1491.59 1.00 2520 137 137 10 FALSE 0.08
uterine cancer KRAS_G12V ZFHX3 46 206 Race:overall -0.15 -1.90 1.64 1416.15 1.00 692 38 198 8 FALSE 0.06
colorectal cancer KRAS_G12V MST1R 137 60 White -2.21 -5.20 -0.37 1437.02 1.00 1399 136 59 1 FALSE 1.16
colorectal cancer KRAS_G12V MST1R 137 60 Race:overall -1.87 -6.50 3.13 1608.33 1.00 1399 136 59 1 FALSE 0.37
colorectal cancer KRAS_G12V MGA 138 99 White -0.32 -1.15 0.46 1213.96 1.00 1364 131 92 7 FALSE 0.36
non-small cell lung cancer KRAS_G12V MGA 137 163 White 0.54 -0.08 1.10 1369.01 1.00 2357 123 149 14 FALSE 1.17
uterine cancer KRAS_G12V MGA 40 93 White -1.36 -3.04 -0.05 766.44 1.00 614 38 91 2 FALSE 1.13
colorectal cancer KRAS_G12V MGA 138 99 Race:overall -0.26 -4.72 4.32 1413.54 1.00 1364 131 92 7 FALSE 0.05
non-small cell lung cancer KRAS_G12V MGA 139 178 Race:overall 0.04 -3.23 2.40 1305.08 1.00 2636 125 164 14 FALSE 0.01
uterine cancer KRAS_G12V MGA 45 104 Race:overall -1.42 -3.48 0.11 934.37 1.00 670 43 102 2 FALSE 0.94
colorectal cancer KRAS_G12V TCF3 138 60 White -0.76 -2.10 0.34 1546.09 1.00 1393 135 57 3 FALSE 0.62
colorectal cancer KRAS_G12V TCF3 138 60 Race:overall -0.63 -4.80 4.12 1423.63 1.00 1393 135 57 3 FALSE 0.12
colorectal cancer KRAS_G12V KMT2B 72 151 White -1.08 -2.06 -0.22 1391.28 1.00 715 67 146 5 FALSE 1.59
non-small cell lung cancer KRAS_G12V KMT2B 82 59 White -0.24 -1.59 0.82 817.85 1.00 1341 79 56 3 FALSE 0.15
colorectal cancer KRAS_G12V KMT2B 72 151 Race:overall -0.84 -5.23 4.10 1443.17 1.00 715 67 146 5 FALSE 0.16
non-small cell lung cancer KRAS_G12V KMT2B 82 59 Race:overall -0.17 -4.54 4.45 1389.36 1.00 1341 79 56 3 FALSE 0.03
colorectal cancer KRAS_G12V TCF7L2 10 21 Asian -0.10 -0.72 0.49 894.01 1.01 110 9 20 1 FALSE 0.12
colorectal cancer KRAS_G12V TCF7L2 14 13 Black -0.10 -0.72 0.48 783.43 1.01 109 13 12 1 FALSE 0.13
colorectal cancer KRAS_G12V TCF7L2 9 21 Unknown -0.10 -0.73 0.45 792.05 1.00 91 8 20 1 FALSE 0.13
colorectal cancer KRAS_G12V TCF7L2 140 239 White -0.04 -0.47 0.39 349.39 1.01 1246 118 217 22 FALSE 0.07
colorectal cancer KRAS_G12V TCF7L2 173 294 Race:overall -0.09 -0.61 0.40 586.49 1.01 1556 148 269 25 FALSE 0.13
colorectal cancer KRAS_G12V MSH3 70 76 White -2.36 -4.99 -0.34 533.58 1.00 747 69 75 1 FALSE 1.37
colorectal cancer KRAS_G12V MSH3 70 76 Race:overall -1.97 -6.49 3.54 1033.84 1.00 747 69 75 1 FALSE 0.40
colorectal cancer KRAS_G12V ANKRD11 137 125 White -1.54 -2.89 -0.44 1431.74 1.00 1352 134 122 3 FALSE 1.83
non-small cell lung cancer KRAS_G12V ANKRD11 137 64 White -0.75 -2.43 0.49 1136.38 1.00 2424 135 62 2 FALSE 0.48
uterine cancer KRAS_G12V ANKRD11 40 73 White -0.47 -1.78 0.64 1411.63 1.00 618 37 70 3 FALSE 0.35
colorectal cancer KRAS_G12V ANKRD11 137 125 Race:overall -1.40 -6.08 3.13 1522.53 1.00 1352 134 122 3 FALSE 0.31
non-small cell lung cancer KRAS_G12V ANKRD11 137 64 Race:overall -0.56 -4.82 4.07 1382.31 1.00 2424 135 62 2 FALSE 0.10
uterine cancer KRAS_G12V ANKRD11 40 73 Race:overall -0.38 -4.92 4.10 1199.03 1.00 618 37 70 3 FALSE 0.07
colorectal cancer KRAS_G12V PGR 137 52 White -1.10 -2.88 0.27 900.75 1.00 1400 135 50 2 FALSE 0.76
non-small cell lung cancer KRAS_G12V PGR 9 13 Black -5.39 -12.57 -0.74 1340.72 1.00 157 9 13 0 FALSE 1.06
non-small cell lung cancer KRAS_G12V PGR 137 63 White -5.49 -12.50 -1.24 1362.30 1.00 2422 137 63 0 FALSE 1.15
uterine cancer KRAS_G12V PGR 40 44 White -1.46 -4.34 0.41 1196.86 1.00 629 39 43 1 FALSE 0.67
colorectal cancer KRAS_G12V PGR 137 52 Race:overall -0.91 -5.33 3.96 1437.74 1.00 1400 135 50 2 FALSE 0.17
non-small cell lung cancer KRAS_G12V PGR 146 76 Race:overall -5.26 -12.16 -0.80 1291.64 1.00 2579 146 76 0 FALSE 1.09
uterine cancer KRAS_G12V PGR 40 44 Race:overall -1.22 -5.61 3.56 1439.33 1.00 629 39 43 1 FALSE 0.23
colorectal cancer KRAS_G12V PLCG2 137 64 White -2.19 -5.19 -0.41 270.03 1.02 1389 136 63 1 FALSE 1.11
non-small cell lung cancer KRAS_G12V PLCG2 137 52 White -1.62 -4.27 0.33 274.96 1.01 2438 136 51 1 FALSE 0.68
uterine cancer KRAS_G12V PLCG2 40 43 White -5.78 -15.06 -0.85 1286.83 1.00 635 40 43 0 FALSE 0.90
colorectal cancer KRAS_G12V PLCG2 137 64 Race:overall -1.89 -6.80 3.65 1516.26 1.01 1389 136 63 1 FALSE 0.38
non-small cell lung cancer KRAS_G12V PLCG2 137 52 Race:overall -1.41 -5.53 3.75 803.53 1.01 2438 136 51 1 FALSE 0.28
uterine cancer KRAS_G12V PLCG2 40 43 Race:overall -4.35 -11.43 2.55 1423.47 1.00 635 40 43 0 FALSE 0.68
colorectal cancer KRAS_G12V POLD1 137 95 White -0.90 -2.02 0.05 990.98 1.00 1380 133 91 4 TRUE 1.07
non-small cell lung cancer KRAS_G12V POLD1 137 49 White 0.02 -1.43 1.08 1170.54 1.00 2438 134 46 3 TRUE 0.01
colorectal cancer KRAS_G12V POLD1 137 95 Race:overall -0.68 -4.66 4.05 1340.09 1.00 1380 133 91 4 TRUE 0.14
non-small cell lung cancer KRAS_G12V POLD1 137 49 Race:overall 0.07 -4.25 4.47 1444.41 1.00 2438 134 46 3 TRUE 0.01
colorectal cancer KRAS_G12V INHBA 137 43 White 0.50 -0.41 1.30 1476.08 1.00 1409 131 37 6 FALSE 0.58
non-small cell lung cancer KRAS_G12V INHBA 137 75 White -0.96 -3.15 0.44 279.77 1.01 2416 135 73 2 FALSE 0.57
colorectal cancer KRAS_G12V INHBA 137 43 Race:overall 0.41 -3.96 4.56 1428.30 1.00 1409 131 37 6 FALSE 0.08
non-small cell lung cancer KRAS_G12V INHBA 137 75 Race:overall -0.86 -5.00 3.71 1216.79 1.00 2416 135 73 2 FALSE 0.17
colorectal cancer KRAS_G12V PREX2 70 78 White -1.44 -3.02 -0.14 1396.76 1.00 748 68 76 2 FALSE 1.22
non-small cell lung cancer KRAS_G12V PREX2 6 12 Black -0.62 -3.40 0.96 1284.40 1.00 93 6 12 0 FALSE 0.24
non-small cell lung cancer KRAS_G12V PREX2 81 86 White -0.17 -1.22 0.76 1224.82 1.01 1320 76 81 5 FALSE 0.13
colorectal cancer KRAS_G12V PREX2 70 78 Race:overall -1.16 -5.26 3.60 1507.32 1.00 748 68 76 2 FALSE 0.23
non-small cell lung cancer KRAS_G12V PREX2 87 98 Race:overall -0.40 -2.56 1.14 1321.96 1.00 1413 82 93 5 FALSE 0.17
colorectal cancer KRAS_G12V AMER1 17 12 Black 0.30 -0.60 1.22 410.02 1.01 121 15 10 2 FALSE 0.30
colorectal cancer KRAS_G12V AMER1 147 135 White 0.24 -0.32 0.81 200.97 1.01 1485 133 121 14 FALSE 0.39
non-small cell lung cancer KRAS_G12V AMER1 9 16 Black -0.34 -3.19 1.12 1312.15 1.00 173 9 16 0 FALSE 0.12
non-small cell lung cancer KRAS_G12V AMER1 148 127 White 0.37 -0.38 1.02 1001.70 1.00 2669 138 117 10 FALSE 0.53
uterine cancer KRAS_G12V AMER1 44 47 White -1.48 -4.60 0.42 1517.73 1.00 723 43 46 1 FALSE 0.65
colorectal cancer KRAS_G12V AMER1 164 147 Race:overall 0.27 -0.58 1.17 1029.78 1.01 1606 148 131 16 FALSE 0.27
non-small cell lung cancer KRAS_G12V AMER1 157 143 Race:overall 0.01 -2.25 1.48 1246.53 1.00 2842 147 133 10 FALSE 0.00
uterine cancer KRAS_G12V AMER1 44 47 Race:overall -1.26 -6.28 3.91 1551.19 1.00 723 43 46 1 FALSE 0.22
colorectal cancer KRAS_G12V HLA-A 137 45 White -1.93 -4.73 -0.05 1375.18 1.00 1409 136 44 1 FALSE 0.94
colorectal cancer KRAS_G12V HLA-A 137 45 Race:overall -1.55 -5.95 3.43 1434.83 1.00 1409 136 44 1 FALSE 0.31
colorectal cancer KRAS_G12V EPHA7 137 69 White -0.30 -1.31 0.56 1115.79 1.00 1391 132 64 5 FALSE 0.27
non-small cell lung cancer KRAS_G12V EPHA7 137 110 White -0.24 -1.31 0.66 1119.91 1.00 2384 132 105 5 FALSE 0.20
colorectal cancer KRAS_G12V EPHA7 137 69 Race:overall -0.20 -4.41 4.00 1313.26 1.00 1391 132 64 5 FALSE 0.04
non-small cell lung cancer KRAS_G12V EPHA7 137 110 Race:overall -0.14 -4.69 4.66 1415.24 1.00 2384 132 105 5 FALSE 0.02
colorectal cancer KRAS_G12V NCOA3 137 45 White -0.95 -2.78 0.41 1322.36 1.00 1406 135 43 2 TRUE 0.60
colorectal cancer KRAS_G12V NCOA3 137 45 Race:overall -0.82 -5.17 3.97 1339.87 1.00 1406 135 43 2 TRUE 0.16
non-small cell lung cancer KRAS_G12V DROSHA 81 42 White 0.11 -1.26 1.24 1457.58 1.00 1356 78 39 3 FALSE 0.06
non-small cell lung cancer KRAS_G12V DROSHA 81 42 Race:overall 0.06 -4.64 4.26 1546.20 1.00 1356 78 39 3 FALSE 0.01
colorectal cancer KRAS_G12V SLX4 70 47 White -0.94 -2.82 0.44 321.65 1.00 771 68 45 2 FALSE 0.57
colorectal cancer KRAS_G12V SLX4 70 47 Race:overall -0.84 -5.00 3.63 1299.04 1.00 771 68 45 2 FALSE 0.16
colorectal cancer KRAS_G12V INPPL1 71 61 White -0.03 -1.05 0.86 1491.26 1.00 768 66 56 5 FALSE 0.02
colorectal cancer KRAS_G12V INPPL1 71 61 Race:overall -0.07 -4.37 4.23 1485.80 1.00 768 66 56 5 FALSE 0.01
colorectal cancer KRAS_G13D SPEN 20 11 Black -1.28 -4.27 0.29 1330.73 1.00 118 20 11 0 FALSE 0.56
colorectal cancer KRAS_G13D SPEN 126 121 White -0.63 -1.63 0.19 1412.47 1.00 1532 120 115 6 FALSE 0.75
colorectal cancer KRAS_G13D SPEN 146 132 Race:overall -0.91 -2.99 0.58 1368.72 1.00 1650 140 126 6 FALSE 0.47
colorectal cancer KRAS_G13D KMT2C 18 14 Asian 0.04 -1.03 0.89 1312.32 1.00 124 17 13 1 FALSE 0.03
colorectal cancer KRAS_G13D KMT2C 20 12 Black -0.07 -1.41 0.78 1120.69 1.00 120 20 12 0 FALSE 0.05
colorectal cancer KRAS_G13D KMT2C 9 11 Unknown 0.47 -0.42 1.88 1164.02 1.00 116 5 7 4 FALSE 0.40
colorectal cancer KRAS_G13D KMT2C 126 157 White 0.10 -0.49 0.64 971.96 1.00 1513 114 145 12 FALSE 0.15
colorectal cancer KRAS_G13D KMT2C 173 194 Race:overall 0.13 -0.63 0.82 1253.23 1.00 1873 156 177 17 FALSE 0.14
colorectal cancer KRAS_G13D TP53 19 124 Asian -0.07 -0.68 0.66 1404.72 1.00 59 5 110 14 TRUE 0.08
colorectal cancer KRAS_G13D TP53 21 117 Black -0.10 -0.72 0.58 1425.21 1.00 38 6 102 15 TRUE 0.12
colorectal cancer KRAS_G13D TP53 7 96 Unknown -0.26 -0.92 0.62 1468.86 1.00 33 1 90 6 TRUE 0.31
colorectal cancer KRAS_G13D TP53 145 1350 White -0.58 -0.91 -0.27 1440.12 1.00 614 70 1275 75 TRUE 3.26
colorectal cancer KRAS_G13D TP53 194 1713 Race:overall -0.30 -0.83 0.28 1456.79 1.00 769 84 1603 110 TRUE 0.55
colorectal cancer KRAS_G13D ATRX 127 96 White -0.44 -1.47 0.41 1152.53 1.00 1537 122 91 5 TRUE 0.45
colorectal cancer KRAS_G13D ATRX 127 96 Race:overall -0.37 -4.51 4.28 1351.66 1.00 1537 122 91 5 TRUE 0.07
colorectal cancer KRAS_G13D ATR 18 11 Asian -0.25 -1.66 0.93 1268.81 1.00 125 17 10 1 FALSE 0.15
colorectal cancer KRAS_G13D ATR 125 88 White -0.15 -1.00 0.64 243.25 1.01 1556 119 82 6 FALSE 0.14
colorectal cancer KRAS_G13D ATR 143 99 Race:overall -0.22 -1.52 1.00 958.04 1.00 1681 136 92 7 FALSE 0.13
colorectal cancer KRAS_G13D PDGFRA 139 44 White 0.16 -1.01 1.13 1266.04 1.00 1753 135 40 4 TRUE 0.11
colorectal cancer KRAS_G13D PDGFRA 139 44 Race:overall 0.18 -4.75 4.62 1433.33 1.00 1753 135 40 4 TRUE 0.03
colorectal cancer KRAS_G13D FBXW7 20 34 Asian 1.06 0.34 1.83 1041.24 1.00 141 11 25 9 TRUE 2.50
colorectal cancer KRAS_G13D FBXW7 21 20 Black 0.78 0.03 1.46 1614.98 1.00 117 17 16 4 TRUE 1.48
colorectal cancer KRAS_G13D FBXW7 6 26 Unknown 0.73 -0.14 1.54 1445.53 1.00 100 4 24 2 TRUE 1.15
colorectal cancer KRAS_G13D FBXW7 141 254 White 0.73 0.29 1.11 1179.35 1.00 1600 110 223 31 TRUE 3.52
colorectal cancer KRAS_G13D FBXW7 188 334 Race:overall 0.82 0.26 1.45 1358.10 1.00 1958 142 288 46 TRUE 2.13
colorectal cancer KRAS_G13D MAP3K1 126 70 White 0.48 -0.36 1.22 1500.83 1.00 1560 118 62 8 FALSE 0.61
colorectal cancer KRAS_G13D MAP3K1 126 70 Race:overall 0.47 -3.81 4.83 1430.23 1.00 1560 118 62 8 FALSE 0.09
colorectal cancer KRAS_G13D NSD1 125 71 White -0.37 -1.51 0.56 1371.67 1.00 1560 121 67 4 FALSE 0.31
colorectal cancer KRAS_G13D NSD1 125 71 Race:overall -0.29 -4.96 4.35 1394.04 1.00 1560 121 67 4 FALSE 0.05
colorectal cancer KRAS_G13D FLT4 125 115 White 0.02 -0.73 0.70 393.71 1.01 1524 116 106 9 TRUE 0.02
colorectal cancer KRAS_G13D FLT4 125 115 Race:overall 0.06 -3.97 4.27 1397.10 1.00 1524 116 106 9 TRUE 0.01
colorectal cancer KRAS_G13D PTPRD 125 85 White -0.28 -1.27 0.54 1444.32 1.00 1551 120 80 5 FALSE 0.26
colorectal cancer KRAS_G13D PTPRD 125 85 Race:overall -0.32 -4.83 3.78 1557.07 1.00 1551 120 80 5 FALSE 0.06
colorectal cancer KRAS_G13D RET 139 58 White 0.32 -0.66 1.13 821.90 1.00 1742 133 52 6 TRUE 0.31
colorectal cancer KRAS_G13D RET 139 58 Race:overall 0.38 -4.09 5.08 1630.35 1.00 1742 133 52 6 TRUE 0.07
colorectal cancer KRAS_G13D KDM5A 126 74 White 0.42 -0.36 1.14 1181.95 1.00 1563 118 66 8 FALSE 0.55
colorectal cancer KRAS_G13D KDM5A 126 74 Race:overall 0.45 -4.01 4.78 1374.28 1.00 1563 118 66 8 FALSE 0.08
colorectal cancer KRAS_G13D PIK3C2G 125 65 White -0.62 -1.92 0.49 1458.69 1.00 1560 122 62 3 FALSE 0.50
colorectal cancer KRAS_G13D PIK3C2G 125 65 Race:overall -0.51 -5.13 4.38 1459.34 1.00 1560 122 62 3 FALSE 0.09
colorectal cancer KRAS_G13D CREBBP 18 13 Asian 0.18 -0.70 0.92 1407.48 1.00 125 17 12 1 TRUE 0.18
colorectal cancer KRAS_G13D CREBBP 20 11 Black 0.26 -0.52 1.06 1426.04 1.00 121 18 9 2 TRUE 0.28
colorectal cancer KRAS_G13D CREBBP 6 11 Unknown 0.24 -0.69 1.12 1281.03 1.00 115 5 10 1 TRUE 0.24
colorectal cancer KRAS_G13D CREBBP 128 148 White 0.26 -0.29 0.77 1061.96 1.00 1512 114 134 14 TRUE 0.46
colorectal cancer KRAS_G13D CREBBP 172 183 Race:overall 0.23 -0.49 0.86 1221.65 1.00 1873 154 165 18 TRUE 0.30
colorectal cancer KRAS_G13D AXIN2 126 87 White 0.50 -0.21 1.12 1189.80 1.00 1550 116 77 10 TRUE 0.80
colorectal cancer KRAS_G13D AXIN2 126 87 Race:overall 0.46 -3.71 4.77 1393.98 1.00 1550 116 77 10 TRUE 0.09
colorectal cancer KRAS_G13D DOT1L 125 67 White -0.08 -1.05 0.82 68.12 1.05 1565 120 62 5 FALSE 0.07
colorectal cancer KRAS_G13D DOT1L 125 67 Race:overall -0.11 -4.32 4.34 1342.50 1.00 1565 120 62 5 FALSE 0.02
colorectal cancer KRAS_G13D PTPRS 18 21 Asian 0.38 -0.26 1.07 1398.86 1.00 117 14 17 4 FALSE 0.56
colorectal cancer KRAS_G13D PTPRS 20 15 Black 0.20 -0.70 0.90 911.52 1.00 119 19 14 1 FALSE 0.22
colorectal cancer KRAS_G13D PTPRS 7 15 Unknown 0.36 -0.36 1.18 1483.82 1.00 111 5 13 2 FALSE 0.47
colorectal cancer KRAS_G13D PTPRS 127 200 White 0.29 -0.17 0.75 739.27 1.00 1471 109 182 18 FALSE 0.64
colorectal cancer KRAS_G13D PTPRS 172 251 Race:overall 0.31 -0.30 0.89 1112.11 1.00 1818 147 226 25 FALSE 0.50
colorectal cancer KRAS_G13D SMARCA4 20 19 Black -0.82 -3.36 0.53 1365.23 1.00 116 20 19 0 FALSE 0.38
colorectal cancer KRAS_G13D SMARCA4 6 14 Unknown -0.16 -1.70 1.21 1359.29 1.00 113 5 13 1 FALSE 0.08
colorectal cancer KRAS_G13D SMARCA4 127 126 White 0.14 -0.53 0.76 1418.38 1.00 1524 115 114 12 FALSE 0.17
colorectal cancer KRAS_G13D SMARCA4 153 159 Race:overall -0.28 -1.80 0.78 1565.04 1.00 1753 140 146 13 FALSE 0.17
colorectal cancer KRAS_G13D PTPRT 10 12 Unknown 2.72 1.01 4.45 1478.56 1.00 116 4 6 6 FALSE 2.83
colorectal cancer KRAS_G13D PTPRT 125 150 White 0.29 -0.34 0.88 1479.58 1.00 1494 112 137 13 FALSE 0.45
colorectal cancer KRAS_G13D PTPRT 135 162 Race:overall 1.47 -0.73 3.95 1402.39 1.00 1610 116 143 19 FALSE 0.67
colorectal cancer KRAS_G13D HGF 125 39 White -0.62 -2.45 0.73 1352.43 1.00 1582 123 37 2 FALSE 0.34
colorectal cancer KRAS_G13D HGF 125 39 Race:overall -0.42 -4.58 4.36 1318.91 1.00 1582 123 37 2 FALSE 0.07
colorectal cancer KRAS_G13D BLM 125 50 White 0.02 -1.13 0.97 1245.37 1.00 1578 121 46 4 TRUE 0.01
colorectal cancer KRAS_G13D BLM 125 50 Race:overall 0.03 -4.32 4.48 1361.19 1.00 1578 121 46 4 TRUE 0.01
colorectal cancer KRAS_G13D PIK3CA 19 33 Asian 0.92 0.40 1.46 1329.52 1.00 139 12 26 7 TRUE 3.18
colorectal cancer KRAS_G13D PIK3CA 21 32 Black 0.85 0.27 1.34 1435.52 1.00 108 15 26 6 TRUE 2.79
colorectal cancer KRAS_G13D PIK3CA 6 30 Unknown 0.80 0.15 1.38 1247.45 1.00 99 4 28 2 TRUE 2.10
colorectal cancer KRAS_G13D PIK3CA 147 403 White 0.88 0.55 1.19 1418.51 1.00 1479 92 348 55 TRUE 7.17
colorectal cancer KRAS_G13D PIK3CA 193 498 Race:overall 0.87 0.40 1.30 1376.31 1.00 1825 123 428 70 TRUE 3.90
colorectal cancer KRAS_G13D ESR1 125 61 White 0.27 -0.66 1.11 362.67 1.00 1563 119 55 6 TRUE 0.25
colorectal cancer KRAS_G13D ESR1 125 61 Race:overall 0.23 -4.13 4.65 1616.34 1.00 1563 119 55 6 TRUE 0.04
colorectal cancer KRAS_G13D ALK 141 95 White 1.09 0.47 1.63 1439.76 1.00 1727 124 78 17 TRUE 3.70
colorectal cancer KRAS_G13D ALK 141 95 Race:overall 0.89 -4.05 4.98 1473.09 1.00 1727 124 78 17 TRUE 0.18
colorectal cancer KRAS_G13D RNF43 23 21 Asian 0.93 -0.03 2.01 965.90 1.00 121 15 13 8 TRUE 1.08
colorectal cancer KRAS_G13D RNF43 20 15 Black -0.56 -2.70 0.68 1171.55 1.00 117 20 15 0 TRUE 0.25
colorectal cancer KRAS_G13D RNF43 126 217 White -0.07 -0.62 0.47 1515.69 1.00 1467 112 203 14 TRUE 0.10
colorectal cancer KRAS_G13D RNF43 169 253 Race:overall 0.11 -1.16 1.11 1391.74 1.00 1705 147 231 22 TRUE 0.07
colorectal cancer KRAS_G13D LATS1 125 40 White -0.08 -1.59 1.02 1202.06 1.00 1583 122 37 3 FALSE 0.05
colorectal cancer KRAS_G13D LATS1 125 40 Race:overall -0.11 -4.49 4.12 1446.39 1.00 1583 122 37 3 FALSE 0.02
colorectal cancer KRAS_G13D LATS2 125 58 White 0.13 -0.96 1.00 1243.91 1.00 1565 120 53 5 FALSE 0.10
colorectal cancer KRAS_G13D LATS2 125 58 Race:overall 0.05 -4.65 4.15 1421.65 1.00 1565 120 53 5 FALSE 0.01
colorectal cancer KRAS_G13D PTEN 18 11 Asian 0.69 -0.12 1.47 1567.32 1.01 154 16 9 2 TRUE 1.06
colorectal cancer KRAS_G13D PTEN 20 12 Black 0.73 -0.04 1.52 1444.07 1.00 125 17 9 3 TRUE 1.23
colorectal cancer KRAS_G13D PTEN 7 17 Unknown 0.72 -0.12 1.52 1467.35 1.00 111 5 15 2 TRUE 1.10
colorectal cancer KRAS_G13D PTEN 143 141 White 0.62 0.12 1.07 1346.58 1.00 1700 126 124 17 TRUE 1.97
colorectal cancer KRAS_G13D PTEN 188 181 Race:overall 0.69 0.04 1.27 1523.50 1.00 2090 164 157 24 TRUE 1.48
colorectal cancer KRAS_G13D BCOR 127 94 White 0.28 -0.47 0.97 1284.71 1.00 1545 118 85 9 FALSE 0.35
colorectal cancer KRAS_G13D BCOR 127 94 Race:overall 0.08 -4.34 4.01 1422.45 1.00 1545 118 85 9 FALSE 0.02
colorectal cancer KRAS_G13D CTNNB1 18 15 Asian 0.75 -0.04 1.64 1533.67 1.00 150 14 11 4 TRUE 1.15
colorectal cancer KRAS_G13D CTNNB1 20 13 Black 0.67 -0.15 1.45 1198.08 1.00 123 17 10 3 TRUE 1.06
colorectal cancer KRAS_G13D CTNNB1 139 124 White 0.47 -0.12 0.99 1540.25 1.00 1687 127 112 12 TRUE 1.06
colorectal cancer KRAS_G13D CTNNB1 177 152 Race:overall 0.63 -0.12 1.31 1277.38 1.00 1960 158 133 19 TRUE 1.11
colorectal cancer KRAS_G13D ARID1A 20 22 Asian 0.33 -0.36 1.18 1176.45 1.00 118 15 17 5 TRUE 0.44
colorectal cancer KRAS_G13D ARID1A 20 24 Black -0.10 -1.36 0.62 375.15 1.01 114 20 24 0 TRUE 0.07
colorectal cancer KRAS_G13D ARID1A 7 15 Unknown 0.22 -0.62 1.09 1204.46 1.00 110 5 13 2 TRUE 0.23
colorectal cancer KRAS_G13D ARID1A 130 249 White 0.18 -0.27 0.57 334.80 1.01 1460 109 228 21 TRUE 0.39
colorectal cancer KRAS_G13D ARID1A 177 310 Race:overall 0.16 -0.53 0.78 592.16 1.00 1802 149 282 28 TRUE 0.21
colorectal cancer KRAS_G13D PIK3R1 126 95 White -0.03 -0.87 0.74 1522.52 1.00 1543 119 88 7 TRUE 0.02
colorectal cancer KRAS_G13D PIK3R1 126 95 Race:overall 0.01 -4.27 4.21 1568.30 1.00 1543 119 88 7 TRUE 0.00
colorectal cancer KRAS_G13D IKZF1 125 69 White 0.36 -0.54 1.07 465.73 1.00 1558 118 62 7 TRUE 0.41
colorectal cancer KRAS_G13D IKZF1 125 69 Race:overall 0.29 -3.92 4.75 1539.82 1.00 1558 118 62 7 TRUE 0.05
colorectal cancer KRAS_G13D TERT 125 75 White 0.06 -0.88 0.84 1332.74 1.00 1555 119 69 6 TRUE 0.05
colorectal cancer KRAS_G13D TERT 125 75 Race:overall 0.04 -4.19 3.68 1587.52 1.00 1555 119 69 6 TRUE 0.01
colorectal cancer KRAS_G13D FAT1 18 15 Asian 0.51 -0.62 1.42 1518.36 1.00 126 16 13 2 FALSE 0.50
colorectal cancer KRAS_G13D FAT1 20 11 Black 0.17 -1.70 1.17 1449.37 1.00 124 20 11 0 FALSE 0.09
colorectal cancer KRAS_G13D FAT1 13 19 Unknown 1.43 0.39 2.89 1326.30 1.00 115 5 11 8 FALSE 1.61
colorectal cancer KRAS_G13D FAT1 131 180 White 0.54 0.07 0.99 1342.09 1.00 1500 111 160 20 FALSE 1.64
colorectal cancer KRAS_G13D FAT1 182 225 Race:overall 0.66 -0.18 1.43 1473.48 1.00 1865 152 195 30 FALSE 0.95
colorectal cancer KRAS_G13D FGFR4 125 39 White 0.79 -0.20 1.66 1480.67 1.00 1586 119 33 6 TRUE 1.00
colorectal cancer KRAS_G13D FGFR4 125 39 Race:overall 0.70 -3.66 4.80 1368.47 1.00 1586 119 33 6 TRUE 0.14
colorectal cancer KRAS_G13D CIC 125 111 White -0.39 -1.49 0.40 899.99 1.00 1532 119 105 6 TRUE 0.39
colorectal cancer KRAS_G13D CIC 125 111 Race:overall -0.33 -4.25 3.48 1570.28 1.00 1532 119 105 6 TRUE 0.06
colorectal cancer KRAS_G13D KDM6A 125 49 White -0.82 -2.51 0.48 1318.66 1.00 1573 123 47 2 FALSE 0.54
colorectal cancer KRAS_G13D KDM6A 125 49 Race:overall -0.65 -4.83 3.79 1501.32 1.00 1573 123 47 2 FALSE 0.12
colorectal cancer KRAS_G13D NCOR1 18 12 Asian -0.82 -4.97 0.85 1097.13 1.00 122 18 12 0 FALSE 0.23
colorectal cancer KRAS_G13D NCOR1 127 108 White 0.34 -0.33 0.99 851.50 1.00 1542 115 96 12 FALSE 0.51
colorectal cancer KRAS_G13D NCOR1 145 120 Race:overall -0.19 -2.83 1.36 1341.12 1.00 1664 133 108 12 FALSE 0.07
colorectal cancer KRAS_G13D POLE 19 13 Asian 0.32 -0.88 1.26 1339.63 1.00 125 17 11 2 TRUE 0.26
colorectal cancer KRAS_G13D POLE 127 115 White 0.39 -0.25 1.00 1524.73 1.00 1531 115 103 12 TRUE 0.68
colorectal cancer KRAS_G13D POLE 146 128 Race:overall 0.35 -0.85 1.49 1473.03 1.00 1656 132 114 14 TRUE 0.26
colorectal cancer KRAS_G13D ABL1 141 59 White 0.05 -0.97 0.95 638.33 1.00 1745 136 54 5 TRUE 0.04
colorectal cancer KRAS_G13D ABL1 141 59 Race:overall 0.04 -4.44 4.62 1392.82 1.00 1745 136 54 5 TRUE 0.01
colorectal cancer KRAS_G13D FOXP1 126 56 White -0.03 -0.81 1.13 2.06 1.84 1570 120 50 6 FALSE 0.02
colorectal cancer KRAS_G13D FOXP1 126 56 Race:overall -0.06 -3.42 3.92 21.68 1.06 1570 120 50 6 FALSE 0.01
colorectal cancer KRAS_G13D NOTCH2 125 64 White 0.21 -0.84 1.01 398.79 1.00 1567 119 58 6 TRUE 0.18
colorectal cancer KRAS_G13D NOTCH2 125 64 Race:overall 0.18 -4.60 4.64 1513.54 1.00 1567 119 58 6 TRUE 0.03
colorectal cancer KRAS_G13D TGFBR2 125 93 White 0.46 -0.29 1.08 351.92 1.01 1539 115 83 10 TRUE 0.71
colorectal cancer KRAS_G13D TGFBR2 125 93 Race:overall 0.43 -3.77 4.64 1383.01 1.00 1539 115 83 10 TRUE 0.08
colorectal cancer KRAS_G13D SMO 140 57 White -0.15 -1.28 0.83 1297.29 1.00 1744 136 53 4 TRUE 0.10
colorectal cancer KRAS_G13D SMO 140 57 Race:overall -0.16 -4.29 4.20 1424.88 1.00 1744 136 53 4 TRUE 0.03
colorectal cancer KRAS_G13D RPS6KA4 126 46 White 0.60 -0.36 1.43 1276.38 1.00 1577 120 40 6 FALSE 0.72
colorectal cancer KRAS_G13D RPS6KA4 126 46 Race:overall 0.58 -3.76 5.16 1514.69 1.00 1577 120 40 6 FALSE 0.11
colorectal cancer KRAS_G13D KMT2A 127 122 White 0.12 -0.63 0.78 1014.89 1.00 1524 117 112 10 FALSE 0.13
colorectal cancer KRAS_G13D KMT2A 127 122 Race:overall 0.07 -3.90 4.00 1413.72 1.00 1524 117 112 10 FALSE 0.01
colorectal cancer KRAS_G13D JAK3 139 51 White -0.37 -1.84 0.66 1252.88 1.00 1749 136 48 3 TRUE 0.25
colorectal cancer KRAS_G13D JAK3 139 51 Race:overall -0.26 -4.59 4.22 1386.15 1.00 1749 136 48 3 TRUE 0.05
colorectal cancer KRAS_G13D BRCA2 18 18 Asian -0.44 -2.30 0.60 1436.28 1.00 126 18 18 0 TRUE 0.23
colorectal cancer KRAS_G13D BRCA2 20 13 Black -0.22 -1.60 0.69 1421.72 1.00 119 19 12 1 TRUE 0.15
colorectal cancer KRAS_G13D BRCA2 131 149 White 0.18 -0.41 0.71 1195.64 1.00 1521 116 134 15 TRUE 0.27
colorectal cancer KRAS_G13D BRCA2 169 180 Race:overall -0.16 -1.46 0.66 1387.69 1.00 1766 153 164 16 TRUE 0.12
colorectal cancer KRAS_G13D NOTCH3 18 18 Asian 0.36 -0.47 1.09 1417.74 1.00 123 15 15 3 TRUE 0.44
colorectal cancer KRAS_G13D NOTCH3 20 12 Black 0.24 -0.67 1.02 1239.11 1.00 120 19 11 1 TRUE 0.25
colorectal cancer KRAS_G13D NOTCH3 6 13 Unknown 0.42 -0.42 1.36 1505.46 1.00 112 4 11 2 TRUE 0.47
colorectal cancer KRAS_G13D NOTCH3 126 154 White 0.30 -0.25 0.81 1113.18 1.00 1507 112 140 14 TRUE 0.60
colorectal cancer KRAS_G13D NOTCH3 170 197 Race:overall 0.34 -0.34 0.98 1458.85 1.00 1862 150 177 20 TRUE 0.50
colorectal cancer KRAS_G13D NOTCH4 126 99 White -0.51 -1.61 0.38 930.60 1.00 1531 121 94 5 TRUE 0.51
colorectal cancer KRAS_G13D NOTCH4 126 99 Race:overall -0.38 -4.56 4.07 1504.51 1.00 1531 121 94 5 TRUE 0.07
colorectal cancer KRAS_G13D FGFR3 139 45 White -0.24 -1.62 0.87 1285.29 1.00 1754 136 42 3 TRUE 0.15
colorectal cancer KRAS_G13D FGFR3 139 45 Race:overall -0.24 -4.54 4.10 1412.19 1.00 1754 136 42 3 TRUE 0.04
colorectal cancer KRAS_G13D IGF1R 125 69 White -0.09 -1.09 0.84 1406.71 1.00 1562 120 64 5 TRUE 0.07
colorectal cancer KRAS_G13D IGF1R 125 69 Race:overall -0.09 -4.36 4.17 1509.33 1.00 1562 120 64 5 TRUE 0.02
colorectal cancer KRAS_G13D KDM5C 20 12 Black -1.80 -5.79 0.35 1117.54 1.00 121 20 12 0 FALSE 0.56
colorectal cancer KRAS_G13D KDM5C 125 51 White -0.62 -2.11 0.49 1365.44 1.00 1574 122 48 3 FALSE 0.47
colorectal cancer KRAS_G13D KDM5C 145 63 Race:overall -1.15 -3.99 0.92 1152.64 1.00 1695 142 60 3 FALSE 0.44
colorectal cancer KRAS_G13D EPHB1 125 65 White -2.05 -4.58 -0.27 1455.51 1.00 1554 124 64 1 FALSE 1.13
colorectal cancer KRAS_G13D EPHB1 125 65 Race:overall -1.69 -6.26 3.44 1490.33 1.00 1554 124 64 1 FALSE 0.33
colorectal cancer KRAS_G13D IRS2 125 71 White -0.11 -1.17 0.75 770.57 1.00 1557 120 66 5 FALSE 0.09
colorectal cancer KRAS_G13D IRS2 125 71 Race:overall -0.07 -4.06 4.33 1304.44 1.00 1557 120 66 5 FALSE 0.01
colorectal cancer KRAS_G13D FANCA 125 51 White 1.03 0.26 1.76 1411.02 1.00 1577 116 42 9 TRUE 2.03
colorectal cancer KRAS_G13D FANCA 125 51 Race:overall 0.84 -3.56 4.86 1492.55 1.00 1577 116 42 9 TRUE 0.17
colorectal cancer KRAS_G13D PIK3CB 125 48 White -1.78 -4.54 0.00 1361.08 1.00 1578 124 47 1 FALSE 0.90
colorectal cancer KRAS_G13D PIK3CB 125 48 Race:overall -1.41 -5.54 3.50 1237.46 1.00 1578 124 47 1 FALSE 0.28
colorectal cancer KRAS_G13D ERBB3 18 11 Asian 0.61 -0.48 1.61 1301.68 1.00 124 16 9 2 TRUE 0.58
colorectal cancer KRAS_G13D ERBB3 127 94 White 0.63 0.01 1.20 1363.43 1.00 1544 115 82 12 TRUE 1.41
colorectal cancer KRAS_G13D ERBB3 145 105 Race:overall 0.64 -0.42 1.70 1469.25 1.00 1668 131 91 14 TRUE 0.57
colorectal cancer KRAS_G13D SMAD4 18 23 Asian -0.30 -1.03 0.41 1501.79 1.00 141 16 21 2 TRUE 0.39
colorectal cancer KRAS_G13D SMAD4 20 27 Black -0.18 -0.89 0.57 1428.50 1.00 112 16 23 4 TRUE 0.21
colorectal cancer KRAS_G13D SMAD4 6 24 Unknown -0.39 -1.24 0.30 1414.43 1.00 101 6 24 0 TRUE 0.47
colorectal cancer KRAS_G13D SMAD4 141 274 White -0.32 -0.84 0.14 1399.87 1.00 1555 126 259 15 TRUE 0.71
colorectal cancer KRAS_G13D SMAD4 185 348 Race:overall -0.30 -0.92 0.28 1433.73 1.00 1909 164 327 21 TRUE 0.48
colorectal cancer KRAS_G13D ATM 18 17 Asian 0.40 -0.40 1.15 1345.08 1.00 150 16 15 2 TRUE 0.51
colorectal cancer KRAS_G13D ATM 21 15 Black 0.38 -0.42 1.13 1478.46 1.00 124 19 13 2 TRUE 0.49
colorectal cancer KRAS_G13D ATM 11 19 Unknown 0.75 -0.02 1.90 794.64 1.00 114 5 13 6 TRUE 0.91
colorectal cancer KRAS_G13D ATM 140 176 White 0.28 -0.23 0.73 1424.79 1.00 1664 126 162 14 TRUE 0.57
colorectal cancer KRAS_G13D ATM 190 227 Race:overall 0.45 -0.17 1.10 1333.89 1.00 2052 166 203 24 TRUE 0.82
colorectal cancer KRAS_G13D RB1 140 57 White -0.51 -1.91 0.58 1090.13 1.00 1748 137 54 3 TRUE 0.36
colorectal cancer KRAS_G13D RB1 140 57 Race:overall -0.42 -4.47 4.20 1503.00 1.00 1748 137 54 3 TRUE 0.08
colorectal cancer KRAS_G13D KMT2D 21 36 Asian 0.32 -0.34 1.09 1468.31 1.00 118 14 29 7 FALSE 0.43
colorectal cancer KRAS_G13D KMT2D 20 23 Black -0.05 -1.06 0.65 1311.84 1.00 113 19 22 1 FALSE 0.05
colorectal cancer KRAS_G13D KMT2D 7 24 Unknown 0.13 -0.67 0.86 1494.80 1.00 108 5 22 2 FALSE 0.13
colorectal cancer KRAS_G13D KMT2D 132 298 White 0.10 -0.34 0.51 1290.08 1.00 1451 109 275 23 FALSE 0.19
colorectal cancer KRAS_G13D KMT2D 180 381 Race:overall 0.13 -0.49 0.72 1393.69 1.00 1790 147 348 33 FALSE 0.17
colorectal cancer KRAS_G13D TSC2 126 91 White 0.00 -0.84 0.74 1465.48 1.00 1548 119 84 7 TRUE 0.00
colorectal cancer KRAS_G13D TSC2 126 91 Race:overall -0.01 -4.07 4.26 1531.82 1.00 1548 119 84 7 TRUE 0.00
colorectal cancer KRAS_G13D APC 24 163 Asian 0.41 -0.20 0.98 1451.33 1.00 70 7 146 17 TRUE 0.79
colorectal cancer KRAS_G13D APC 32 187 Black 0.69 0.12 1.29 1458.58 1.00 36 3 158 29 TRUE 1.64
colorectal cancer KRAS_G13D APC 16 156 Unknown 0.43 -0.21 1.07 1462.97 1.00 28 2 142 14 TRUE 0.75
colorectal cancer KRAS_G13D APC 204 1977 White 0.42 0.10 0.77 1564.78 1.00 622 37 1810 167 TRUE 1.84
colorectal cancer KRAS_G13D APC 280 2530 Race:overall 0.45 -0.06 0.93 1523.69 1.00 775 50 2300 230 TRUE 1.14
colorectal cancer KRAS_G13D ERBB2 140 84 White 0.56 -0.15 1.24 792.40 1.00 1725 130 74 10 TRUE 0.91
colorectal cancer KRAS_G13D ERBB2 140 84 Race:overall 0.49 -3.88 4.70 1500.85 1.00 1725 130 74 10 TRUE 0.09
colorectal cancer KRAS_G13D JAK1 125 58 White 0.67 -0.06 1.48 71.39 1.01 1574 117 50 8 TRUE 0.95
colorectal cancer KRAS_G13D JAK1 125 58 Race:overall 0.62 -3.44 4.78 1142.86 1.00 1574 117 50 8 TRUE 0.13
colorectal cancer KRAS_G13D ARID2 125 89 White -0.16 -1.07 0.65 1316.32 1.00 1543 119 83 6 FALSE 0.14
colorectal cancer KRAS_G13D ARID2 125 89 Race:overall -0.14 -4.88 4.81 1366.98 1.00 1543 119 83 6 FALSE 0.02
colorectal cancer KRAS_G13D SOX17 125 80 White 0.33 -0.49 1.05 1347.69 1.00 1551 117 72 8 FALSE 0.40
colorectal cancer KRAS_G13D SOX17 125 80 Race:overall 0.26 -4.24 4.70 1332.80 1.00 1551 117 72 8 FALSE 0.05
colorectal cancer KRAS_G13D MTOR 20 12 Black -1.02 -5.38 0.91 206.86 1.02 118 20 12 0 TRUE 0.25
colorectal cancer KRAS_G13D MTOR 129 111 White 0.63 0.03 1.19 1088.55 1.01 1533 114 96 15 TRUE 1.52
colorectal cancer KRAS_G13D MTOR 149 123 Race:overall -0.17 -3.25 1.73 936.64 1.01 1651 134 108 15 TRUE 0.05
colorectal cancer KRAS_G13D IRS1 128 81 White 0.29 -0.53 1.00 1126.24 1.00 1550 120 73 8 FALSE 0.33
colorectal cancer KRAS_G13D IRS1 128 81 Race:overall 0.26 -4.27 4.30 1328.78 1.00 1550 120 73 8 FALSE 0.05
colorectal cancer KRAS_G13D NOTCH1 19 13 Asian 0.37 -0.49 1.11 1013.09 1.00 153 16 10 3 TRUE 0.45
colorectal cancer KRAS_G13D NOTCH1 20 13 Black 0.13 -1.07 0.86 605.70 1.00 125 20 13 0 TRUE 0.10
colorectal cancer KRAS_G13D NOTCH1 6 11 Unknown 0.18 -0.99 0.92 754.48 1.00 113 6 11 0 TRUE 0.14
colorectal cancer KRAS_G13D NOTCH1 145 133 White 0.36 -0.21 0.87 380.62 1.00 1699 130 118 15 TRUE 0.71
colorectal cancer KRAS_G13D NOTCH1 190 170 Race:overall 0.25 -0.59 0.88 503.63 1.00 2090 172 152 18 TRUE 0.30
colorectal cancer KRAS_G13D NTRK1 125 46 White -0.26 -1.69 0.80 1376.86 1.00 1575 122 43 3 TRUE 0.16
colorectal cancer KRAS_G13D NTRK1 125 46 Race:overall -0.22 -4.64 4.12 1533.24 1.00 1575 122 43 3 TRUE 0.04
colorectal cancer KRAS_G13D CASP8 129 73 White 1.14 0.47 1.70 1242.95 1.00 1561 115 59 14 FALSE 3.50
colorectal cancer KRAS_G13D CASP8 129 73 Race:overall 0.89 -3.65 5.06 1633.24 1.00 1561 115 59 14 FALSE 0.18
colorectal cancer KRAS_G13D SETD2 127 89 White 0.61 -0.09 1.21 971.17 1.00 1550 116 78 11 FALSE 1.15
colorectal cancer KRAS_G13D SETD2 127 89 Race:overall 0.45 -4.12 4.93 1536.41 1.00 1550 116 78 11 FALSE 0.08
colorectal cancer KRAS_G13D PBRM1 127 77 White -0.01 -0.99 0.80 1385.15 1.00 1554 121 71 6 TRUE 0.01
colorectal cancer KRAS_G13D PBRM1 127 77 Race:overall 0.01 -4.60 4.56 1499.28 1.00 1554 121 71 6 TRUE 0.00
colorectal cancer KRAS_G13D EPHA3 18 11 Asian 0.06 -1.95 1.14 913.12 1.00 124 18 11 0 FALSE 0.03
colorectal cancer KRAS_G13D EPHA3 8 12 Unknown 0.84 -0.29 2.18 1486.78 1.00 113 5 9 3 FALSE 0.75
colorectal cancer KRAS_G13D EPHA3 125 81 White 0.47 -0.25 1.10 1090.35 1.00 1550 116 72 9 FALSE 0.78
colorectal cancer KRAS_G13D EPHA3 151 104 Race:overall 0.45 -0.77 1.44 1183.15 1.00 1787 139 92 12 FALSE 0.37
colorectal cancer KRAS_G13D KIT 139 38 White -5.61 -15.27 -0.72 692.76 1.01 1756 139 38 0 TRUE 0.63
colorectal cancer KRAS_G13D KIT 139 38 Race:overall -4.17 -11.81 2.81 901.86 1.00 1756 139 38 0 TRUE 0.64
colorectal cancer KRAS_G13D KDR 141 55 White 0.39 -0.59 1.19 1289.31 1.00 1747 135 49 6 TRUE 0.40
colorectal cancer KRAS_G13D KDR 141 55 Race:overall 0.35 -4.09 4.44 1571.98 1.00 1747 135 49 6 TRUE 0.06
colorectal cancer KRAS_G13D RICTOR 126 60 White 0.66 -0.18 1.42 1467.20 1.00 1572 118 52 8 FALSE 0.95
colorectal cancer KRAS_G13D RICTOR 126 60 Race:overall 0.63 -4.09 4.73 1328.59 1.00 1572 118 52 8 FALSE 0.12
colorectal cancer KRAS_G13D RAD50 126 42 White 0.17 -1.14 1.15 1212.34 1.00 1582 122 38 4 FALSE 0.11
colorectal cancer KRAS_G13D RAD50 126 42 Race:overall 0.17 -4.29 4.88 1543.86 1.00 1582 122 38 4 FALSE 0.03
colorectal cancer KRAS_G13D CSF1R 139 41 White -0.18 -1.64 0.95 1188.04 1.00 1760 136 38 3 TRUE 0.10
colorectal cancer KRAS_G13D CSF1R 139 41 Race:overall -0.02 -4.76 5.03 1512.79 1.00 1760 136 38 3 TRUE 0.00
colorectal cancer KRAS_G13D PTCH1 130 115 White 0.49 -0.16 1.11 565.82 1.00 1533 117 102 13 TRUE 0.90
colorectal cancer KRAS_G13D PTCH1 130 115 Race:overall 0.30 -4.33 4.43 1529.49 1.00 1533 117 102 13 TRUE 0.05
colorectal cancer KRAS_G13D TET1 125 76 White -0.43 -1.54 0.49 1473.31 1.00 1557 121 72 4 FALSE 0.39
colorectal cancer KRAS_G13D TET1 125 76 Race:overall -0.34 -4.55 4.21 1313.59 1.00 1557 121 72 4 FALSE 0.06
colorectal cancer KRAS_G13D FGFR2 139 38 White -0.06 -1.49 1.00 1129.93 1.00 1759 136 35 3 TRUE 0.03
colorectal cancer KRAS_G13D FGFR2 139 38 Race:overall 0.01 -4.48 4.76 1254.72 1.00 1759 136 35 3 TRUE 0.00
colorectal cancer KRAS_G13D TBX3 126 57 White 0.15 -0.88 1.06 1364.47 1.00 1571 121 52 5 FALSE 0.12
colorectal cancer KRAS_G13D TBX3 126 57 Race:overall 0.10 -4.49 4.51 1578.78 1.00 1571 121 52 5 FALSE 0.02
colorectal cancer KRAS_G13D HNF1A 139 40 White 0.23 -1.06 1.20 1289.65 1.00 1757 135 36 4 TRUE 0.16
colorectal cancer KRAS_G13D HNF1A 139 40 Race:overall 0.28 -3.94 4.87 1599.57 1.00 1757 135 36 4 TRUE 0.05
colorectal cancer KRAS_G13D DICER1 18 12 Asian 0.15 -1.38 1.45 1493.43 1.00 125 16 10 2 TRUE 0.08
colorectal cancer KRAS_G13D DICER1 125 49 White -0.21 -1.37 0.76 1529.42 1.00 1575 122 46 3 TRUE 0.15
colorectal cancer KRAS_G13D DICER1 143 61 Race:overall -0.02 -1.75 1.57 1536.30 1.00 1700 138 56 5 TRUE 0.01
colorectal cancer KRAS_G13D SMAD3 18 14 Asian -1.32 -5.18 0.58 1175.31 1.00 119 18 14 0 TRUE 0.40
colorectal cancer KRAS_G13D SMAD3 125 84 White -0.05 -0.97 0.75 1473.43 1.00 1551 118 77 7 TRUE 0.04
colorectal cancer KRAS_G13D SMAD3 143 98 Race:overall -0.66 -3.41 1.08 1204.61 1.00 1670 136 91 7 TRUE 0.25
colorectal cancer KRAS_G13D NTRK3 125 60 White -1.09 -2.88 0.24 797.25 1.00 1564 123 58 2 FALSE 0.75
colorectal cancer KRAS_G13D NTRK3 125 60 Race:overall -0.94 -5.28 3.77 1236.84 1.00 1564 123 58 2 FALSE 0.18
colorectal cancer KRAS_G13D AXIN1 125 57 White 0.15 -0.92 1.02 1559.28 1.00 1570 120 52 5 FALSE 0.12
colorectal cancer KRAS_G13D AXIN1 125 57 Race:overall 0.16 -3.99 4.66 1506.09 1.00 1570 120 52 5 FALSE 0.03
colorectal cancer KRAS_G13D GRIN2A 18 11 Asian -0.29 -1.92 0.92 1122.01 1.00 124 17 10 1 FALSE 0.17
colorectal cancer KRAS_G13D GRIN2A 125 107 White -0.23 -1.12 0.51 508.61 1.00 1525 118 100 7 FALSE 0.24
colorectal cancer KRAS_G13D GRIN2A 143 118 Race:overall -0.23 -1.54 1.02 1002.05 1.00 1649 135 110 8 FALSE 0.14
colorectal cancer KRAS_G13D PALB2 125 44 White 0.39 -0.69 1.34 226.59 1.01 1579 120 39 5 TRUE 0.32
colorectal cancer KRAS_G13D PALB2 125 44 Race:overall 0.33 -4.22 5.14 1429.94 1.00 1579 120 39 5 TRUE 0.06
colorectal cancer KRAS_G13D CTCF 128 71 White 0.76 0.04 1.42 1293.85 1.00 1562 118 61 10 FALSE 1.49
colorectal cancer KRAS_G13D CTCF 128 71 Race:overall 0.65 -3.69 4.82 1470.28 1.00 1562 118 61 10 FALSE 0.13
colorectal cancer KRAS_G13D CDH1 139 43 White -0.20 -1.66 0.88 1312.40 1.00 1759 136 40 3 TRUE 0.12
colorectal cancer KRAS_G13D CDH1 139 43 Race:overall -0.06 -4.32 4.93 1661.21 1.00 1759 136 40 3 TRUE 0.01
colorectal cancer KRAS_G13D CDK12 126 76 White -0.03 -0.80 0.78 38.65 1.05 1559 120 70 6 FALSE 0.03
colorectal cancer KRAS_G13D CDK12 126 76 Race:overall 0.02 -3.75 4.21 1200.46 1.00 1559 120 70 6 FALSE 0.00
colorectal cancer KRAS_G13D DNMT1 125 71 White 0.49 -0.34 1.20 1176.64 1.00 1562 117 63 8 FALSE 0.67
colorectal cancer KRAS_G13D DNMT1 125 71 Race:overall 0.44 -3.99 4.66 1450.12 1.00 1562 117 63 8 FALSE 0.08
colorectal cancer KRAS_G13D BRD4 125 69 White -0.36 -1.58 0.58 1061.55 1.00 1555 121 65 4 FALSE 0.29
colorectal cancer KRAS_G13D BRD4 125 69 Race:overall -0.31 -4.55 4.17 1681.30 1.00 1555 121 65 4 FALSE 0.06
colorectal cancer KRAS_G13D ASXL1 125 85 White 0.24 -0.56 0.97 1513.27 1.00 1547 117 77 8 TRUE 0.27
colorectal cancer KRAS_G13D ASXL1 125 85 Race:overall 0.16 -4.11 4.46 1517.64 1.00 1547 117 77 8 TRUE 0.03
colorectal cancer KRAS_G13D EP300 127 107 White -0.22 -1.16 0.53 1034.94 1.00 1534 120 100 7 TRUE 0.21
colorectal cancer KRAS_G13D EP300 127 107 Race:overall -0.12 -4.00 4.43 1580.29 1.00 1534 120 100 7 TRUE 0.02
colorectal cancer KRAS_G13D ERBB4 10 13 Unknown 1.92 0.61 3.46 1380.02 1.00 114 5 8 5 TRUE 2.01
colorectal cancer KRAS_G13D ERBB4 141 109 White 0.86 0.28 1.44 733.14 1.00 1709 126 94 15 TRUE 2.55
colorectal cancer KRAS_G13D ERBB4 151 122 Race:overall 1.35 -0.13 3.08 1314.74 1.00 1823 131 102 20 TRUE 1.04
colorectal cancer KRAS_G13D MDC1 126 51 White 0.47 -0.51 1.29 1199.58 1.00 1576 120 45 6 FALSE 0.52
colorectal cancer KRAS_G13D MDC1 126 51 Race:overall 0.40 -4.17 4.67 1370.10 1.00 1576 120 45 6 FALSE 0.07
colorectal cancer KRAS_G13D RECQL4 125 64 White 0.01 -0.96 0.89 1546.42 1.00 1564 120 59 5 TRUE 0.01
colorectal cancer KRAS_G13D RECQL4 125 64 Race:overall 0.04 -4.27 4.21 1420.39 1.00 1564 120 59 5 TRUE 0.01
colorectal cancer KRAS_G13D MED12 128 95 White 0.26 -0.52 0.90 802.18 1.00 1542 119 86 9 TRUE 0.32
colorectal cancer KRAS_G13D MED12 128 95 Race:overall 0.25 -4.40 4.53 1366.47 1.00 1542 119 86 9 TRUE 0.04
colorectal cancer KRAS_G13D ERCC5 125 46 White -0.30 -1.82 0.82 1000.68 1.00 1574 122 43 3 TRUE 0.18
colorectal cancer KRAS_G13D ERCC5 125 46 Race:overall -0.24 -4.75 4.11 1420.74 1.00 1574 122 43 3 TRUE 0.04
colorectal cancer KRAS_G13D PIK3CD 125 58 White -0.16 -1.35 0.82 1501.32 1.00 1567 121 54 4 FALSE 0.11
colorectal cancer KRAS_G13D PIK3CD 125 58 Race:overall -0.10 -4.43 4.23 1481.89 1.00 1567 121 54 4 FALSE 0.02
colorectal cancer KRAS_G13D BRCA1 127 56 White 0.74 -0.07 1.49 1359.28 1.00 1572 119 48 8 TRUE 1.18
colorectal cancer KRAS_G13D BRCA1 127 56 Race:overall 0.54 -3.99 5.00 1519.41 1.00 1572 119 48 8 TRUE 0.10
colorectal cancer KRAS_G13D RBM10 125 54 White -0.41 -1.76 0.69 1013.04 1.00 1569 122 51 3 FALSE 0.29
colorectal cancer KRAS_G13D RBM10 125 54 Race:overall -0.39 -4.70 4.36 1269.04 1.00 1569 122 51 3 FALSE 0.07
colorectal cancer KRAS_G13D TSC1 126 60 White 0.68 -0.17 1.36 1517.62 1.00 1574 118 52 8 TRUE 1.07
colorectal cancer KRAS_G13D TSC1 126 60 Race:overall 0.60 -3.91 4.91 1600.14 1.00 1574 118 52 8 TRUE 0.12
colorectal cancer KRAS_G13D FLCN 125 45 White -0.73 -2.56 0.55 1285.73 1.00 1577 123 43 2 TRUE 0.44
colorectal cancer KRAS_G13D FLCN 125 45 Race:overall -0.73 -4.71 3.91 1598.31 1.00 1577 123 43 2 TRUE 0.15
colorectal cancer KRAS_G13D NF1 125 113 White -0.21 -1.12 0.55 1254.81 1.00 1537 118 106 7 TRUE 0.21
colorectal cancer KRAS_G13D NF1 125 113 Race:overall -0.15 -3.87 4.31 1312.13 1.00 1537 118 106 7 TRUE 0.03
colorectal cancer KRAS_G13D FLT1 125 68 White 0.52 -0.26 1.19 1516.29 1.00 1567 117 60 8 FALSE 0.79
colorectal cancer KRAS_G13D FLT1 125 68 Race:overall 0.53 -4.06 4.96 1415.96 1.00 1567 117 60 8 FALSE 0.10
colorectal cancer KRAS_G13D RPTOR 125 52 White -0.36 -1.62 0.65 925.58 1.01 1569 122 49 3 FALSE 0.27
colorectal cancer KRAS_G13D RPTOR 125 52 Race:overall -0.29 -4.21 3.67 1377.32 1.00 1569 122 49 3 FALSE 0.06
colorectal cancer KRAS_G13D RASA1 125 58 White -0.14 -1.41 0.80 482.61 1.00 1574 121 54 4 FALSE 0.09
colorectal cancer KRAS_G13D RASA1 125 58 Race:overall -0.16 -4.44 3.57 1487.71 1.00 1574 121 54 4 FALSE 0.03
colorectal cancer KRAS_G13D EPHA5 18 11 Asian -0.72 -3.35 0.78 1487.41 1.00 127 18 11 0 FALSE 0.32
colorectal cancer KRAS_G13D EPHA5 9 12 Unknown 0.79 -0.78 2.80 794.10 1.00 114 5 8 4 FALSE 0.38
colorectal cancer KRAS_G13D EPHA5 125 115 White -0.58 -1.58 0.21 1263.39 1.00 1520 121 111 4 FALSE 0.68
colorectal cancer KRAS_G13D EPHA5 152 138 Race:overall -0.18 -1.65 1.27 1453.45 1.00 1761 144 130 8 FALSE 0.10
colorectal cancer KRAS_G13D AR 126 86 White 0.08 -0.77 0.80 1386.80 1.00 1539 119 79 7 TRUE 0.07
colorectal cancer KRAS_G13D AR 126 86 Race:overall 0.03 -4.53 4.35 1340.89 1.00 1539 119 79 7 TRUE 0.01
colorectal cancer KRAS_G13D GNAS 141 66 White 1.04 0.38 1.68 989.08 1.00 1741 129 54 12 TRUE 2.80
colorectal cancer KRAS_G13D GNAS 141 66 Race:overall 0.84 -3.73 4.98 1421.44 1.00 1741 129 54 12 TRUE 0.17
colorectal cancer KRAS_G13D ASXL2 126 60 White -0.20 -1.40 0.82 1066.12 1.00 1576 122 56 4 FALSE 0.14
colorectal cancer KRAS_G13D ASXL2 126 60 Race:overall -0.19 -4.86 4.23 1292.28 1.00 1576 122 56 4 FALSE 0.03
colorectal cancer KRAS_G13D SF3B1 131 51 White 1.61 0.96 2.23 1327.26 1.00 1581 117 37 14 TRUE 6.11
colorectal cancer KRAS_G13D SF3B1 131 51 Race:overall 1.32 -3.25 5.24 1396.94 1.00 1581 117 37 14 TRUE 0.29
colorectal cancer KRAS_G13D MLH1 141 49 White 1.04 0.24 1.75 1362.31 1.00 1759 132 40 9 TRUE 2.24
colorectal cancer KRAS_G13D MLH1 141 49 Race:overall 0.89 -3.76 5.48 1455.92 1.00 1759 132 40 9 TRUE 0.17
colorectal cancer KRAS_G13D ROS1 18 16 Asian 0.66 -0.63 1.92 1433.36 1.00 125 14 12 4 TRUE 0.51
colorectal cancer KRAS_G13D ROS1 125 71 White -0.42 -1.62 0.54 1558.79 1.00 1553 122 68 3 TRUE 0.34
colorectal cancer KRAS_G13D ROS1 143 87 Race:overall 0.12 -1.64 1.78 1577.77 1.00 1678 136 80 7 TRUE 0.05
colorectal cancer KRAS_G13D PIK3R2 125 36 White 0.40 -0.91 1.37 590.68 1.01 1584 121 32 4 FALSE 0.30
colorectal cancer KRAS_G13D PIK3R2 125 36 Race:overall 0.40 -3.82 4.71 1327.68 1.00 1584 121 32 4 FALSE 0.07
colorectal cancer KRAS_G13D FLT3 139 36 White -0.52 -2.16 0.72 946.44 1.00 1762 137 34 2 TRUE 0.31
colorectal cancer KRAS_G13D FLT3 139 36 Race:overall -0.39 -5.02 4.12 1373.12 1.00 1762 137 34 2 TRUE 0.07
colorectal cancer KRAS_G13D MSH2 126 63 White -0.26 -1.45 0.76 1153.34 1.00 1572 122 59 4 TRUE 0.19
colorectal cancer KRAS_G13D MSH2 126 63 Race:overall -0.30 -4.94 3.94 1568.99 1.00 1572 122 59 4 TRUE 0.05
colorectal cancer KRAS_G13D AXL 127 67 White 0.95 0.24 1.57 1224.70 1.00 1567 116 56 11 FALSE 2.18
colorectal cancer KRAS_G13D AXL 127 67 Race:overall 0.77 -3.91 4.98 1285.29 1.00 1567 116 56 11 FALSE 0.16
colorectal cancer KRAS_G13D PIK3CG 126 89 White -0.65 -1.92 0.34 1279.91 1.00 1538 122 85 4 FALSE 0.61
colorectal cancer KRAS_G13D PIK3CG 126 89 Race:overall -0.60 -4.84 3.89 1542.73 1.00 1538 122 85 4 FALSE 0.12
colorectal cancer KRAS_G13D MAP2K4 126 53 White 0.83 0.04 1.58 1230.55 1.00 1571 118 45 8 TRUE 1.43
colorectal cancer KRAS_G13D MAP2K4 126 53 Race:overall 0.72 -3.64 4.78 1542.33 1.00 1571 118 45 8 TRUE 0.15
colorectal cancer KRAS_G13D EGFR 140 59 White -0.18 -1.37 0.82 1051.15 1.00 1743 136 55 4 TRUE 0.13
colorectal cancer KRAS_G13D EGFR 140 59 Race:overall -0.17 -4.85 4.65 1449.97 1.00 1743 136 55 4 TRUE 0.03
colorectal cancer KRAS_G13D ARID1B 125 121 White -0.01 -0.80 0.66 1353.64 1.00 1523 116 112 9 TRUE 0.01
colorectal cancer KRAS_G13D ARID1B 125 121 Race:overall 0.03 -4.37 4.38 1532.75 1.00 1523 116 112 9 TRUE 0.00
colorectal cancer KRAS_G13D ARID5B 126 53 White -0.94 -2.63 0.39 1351.67 1.00 1577 124 51 2 FALSE 0.62
colorectal cancer KRAS_G13D ARID5B 126 53 Race:overall -0.80 -5.05 4.17 1441.75 1.00 1577 124 51 2 FALSE 0.15
colorectal cancer KRAS_G13D BRAF 18 15 Asian -1.04 -2.11 -0.11 1133.21 1.00 146 18 15 0 TRUE 1.32
colorectal cancer KRAS_G13D BRAF 20 14 Black -0.94 -1.93 -0.02 1042.28 1.00 120 19 13 1 TRUE 1.27
colorectal cancer KRAS_G13D BRAF 6 13 Unknown -0.78 -1.75 0.47 1344.92 1.00 112 4 11 2 TRUE 0.81
colorectal cancer KRAS_G13D BRAF 139 207 White -1.05 -1.83 -0.38 1146.74 1.00 1601 134 202 5 TRUE 2.26
colorectal cancer KRAS_G13D BRAF 183 249 Race:overall -0.96 -1.80 -0.15 1048.32 1.00 1979 175 241 8 TRUE 1.62
colorectal cancer KRAS_G13D B2M 19 16 Asian 0.66 -0.24 1.49 1588.78 1.00 125 16 13 3 FALSE 0.89
colorectal cancer KRAS_G13D B2M 7 11 Unknown 0.73 -0.23 1.86 1572.95 1.00 116 5 9 2 FALSE 0.83
colorectal cancer KRAS_G13D B2M 129 102 White 0.53 -0.07 1.08 1472.92 1.00 1558 118 91 11 FALSE 1.11
colorectal cancer KRAS_G13D B2M 155 129 Race:overall 0.64 -0.14 1.43 1484.32 1.00 1799 139 113 16 FALSE 0.94
colorectal cancer KRAS_G13D TGFBR1 125 33 White -0.47 -2.25 0.90 1401.33 1.00 1588 123 31 2 FALSE 0.25
colorectal cancer KRAS_G13D TGFBR1 125 33 Race:overall -0.41 -4.55 4.03 1537.50 1.00 1588 123 31 2 FALSE 0.08
colorectal cancer KRAS_G13D TET2 126 67 White -0.06 -1.00 0.82 1202.85 1.00 1564 121 62 5 TRUE 0.05
colorectal cancer KRAS_G13D TET2 126 67 Race:overall 0.10 -4.56 4.95 1403.95 1.00 1564 121 62 5 TRUE 0.02
colorectal cancer KRAS_G13D PDGFRB 125 38 White 0.87 -0.07 1.72 943.15 1.00 1584 119 32 6 TRUE 1.21
colorectal cancer KRAS_G13D PDGFRB 125 38 Race:overall 0.72 -4.03 4.97 1380.98 1.00 1584 119 32 6 TRUE 0.14
colorectal cancer KRAS_G13D CARD11 128 106 White 0.25 -0.50 0.90 850.58 1.00 1527 118 96 10 FALSE 0.31
colorectal cancer KRAS_G13D CARD11 128 106 Race:overall 0.36 -3.48 4.93 1367.88 1.00 1527 118 96 10 FALSE 0.07
colorectal cancer KRAS_G13D DNMT3A 126 40 White 0.27 -0.96 1.27 1359.86 1.00 1582 122 36 4 TRUE 0.20
colorectal cancer KRAS_G13D DNMT3A 126 40 Race:overall 0.20 -4.51 4.46 1444.89 1.00 1582 122 36 4 TRUE 0.03
colorectal cancer KRAS_G13D MSH6 127 83 White 0.28 -0.55 1.01 1308.44 1.00 1554 119 75 8 TRUE 0.33
colorectal cancer KRAS_G13D MSH6 127 83 Race:overall 0.13 -4.43 4.15 1509.67 1.00 1554 119 75 8 TRUE 0.02
colorectal cancer KRAS_G13D SOX9 18 21 Asian 0.17 -1.17 1.00 1316.07 1.00 115 17 20 1 FALSE 0.12
colorectal cancer KRAS_G13D SOX9 20 15 Black 0.45 -0.51 1.26 1442.84 1.00 116 17 12 3 FALSE 0.51
colorectal cancer KRAS_G13D SOX9 127 209 White 0.64 0.21 1.06 1477.91 1.00 1451 100 182 27 FALSE 2.40
colorectal cancer KRAS_G13D SOX9 165 245 Race:overall 0.42 -0.46 1.08 1448.19 1.00 1682 134 214 31 FALSE 0.52
colorectal cancer KRAS_G13D ETV1 126 44 White 0.65 -0.26 1.47 533.79 1.01 1580 120 38 6 TRUE 0.87
colorectal cancer KRAS_G13D ETV1 126 44 Race:overall 0.60 -3.58 4.26 1547.37 1.00 1580 120 38 6 TRUE 0.13
colorectal cancer KRAS_G13D ARAF 126 50 White 0.33 -0.76 1.24 772.03 1.00 1575 121 45 5 FALSE 0.28
colorectal cancer KRAS_G13D ARAF 126 50 Race:overall 0.19 -4.24 4.47 1425.38 1.00 1575 121 45 5 FALSE 0.03
colorectal cancer KRAS_G13D SMAD2 127 74 White 0.67 0.07 1.29 1387.22 1.00 1560 117 64 10 TRUE 1.68
colorectal cancer KRAS_G13D SMAD2 127 74 Race:overall 0.63 -3.30 3.98 1254.58 1.00 1560 117 64 10 TRUE 0.16
colorectal cancer KRAS_G13D JUN 125 41 White -0.63 -2.50 0.71 1272.26 1.00 1580 123 39 2 FALSE 0.36
colorectal cancer KRAS_G13D JUN 125 41 Race:overall -0.57 -5.02 3.84 1492.60 1.00 1580 123 39 2 FALSE 0.11
colorectal cancer KRAS_G13D DNMT3B 125 46 White 0.12 -1.09 1.13 1431.62 1.00 1581 121 42 4 FALSE 0.08
colorectal cancer KRAS_G13D DNMT3B 125 46 Race:overall 0.10 -4.25 4.12 1454.04 1.00 1581 121 42 4 FALSE 0.02
colorectal cancer KRAS_G13D FGFR1 139 37 White -1.52 -4.42 0.38 1376.07 1.00 1761 138 36 1 TRUE 0.67
colorectal cancer KRAS_G13D FGFR1 139 37 Race:overall -1.29 -5.57 3.37 1355.49 1.00 1761 138 36 1 TRUE 0.25
colorectal cancer KRAS_G13D MITF 125 42 White -0.69 -2.52 0.74 1329.85 1.00 1575 123 40 2 FALSE 0.39
colorectal cancer KRAS_G13D MITF 125 42 Race:overall -0.71 -5.58 4.06 1494.66 1.00 1575 123 40 2 FALSE 0.12
colorectal cancer KRAS_G13D SH2B3 110 41 White -0.12 -1.58 0.98 1155.03 1.00 1439 107 38 3 FALSE 0.07
colorectal cancer KRAS_G13D SH2B3 110 41 Race:overall -0.06 -4.03 4.16 1484.48 1.00 1439 107 38 3 FALSE 0.01
colorectal cancer KRAS_G13D GLI1 17 11 Asian 0.57 -0.88 1.86 1088.09 1.00 114 14 8 3 FALSE 0.38
colorectal cancer KRAS_G13D GLI1 110 65 White -0.26 -1.46 0.69 1123.76 1.00 1417 107 62 3 FALSE 0.19
colorectal cancer KRAS_G13D GLI1 127 76 Race:overall 0.13 -1.74 1.82 1331.91 1.00 1531 121 70 6 FALSE 0.06
colorectal cancer KRAS_G13D ZFHX3 16 18 Asian 0.11 -0.77 0.98 1364.69 1.00 112 14 16 2 FALSE 0.09
colorectal cancer KRAS_G13D ZFHX3 9 15 Unknown 0.39 -0.51 1.71 1186.25 1.00 105 5 11 4 FALSE 0.32
colorectal cancer KRAS_G13D ZFHX3 112 183 White -0.05 -0.66 0.54 908.88 1.00 1350 102 173 10 FALSE 0.06
colorectal cancer KRAS_G13D ZFHX3 137 216 Race:overall 0.16 -0.59 1.05 1187.50 1.00 1567 121 200 16 FALSE 0.15
colorectal cancer KRAS_G13D MST1R 110 60 White 0.36 -0.55 1.16 1486.68 1.00 1431 104 54 6 FALSE 0.38
colorectal cancer KRAS_G13D MST1R 110 60 Race:overall 0.27 -3.86 4.56 1484.36 1.00 1431 104 54 6 FALSE 0.05
colorectal cancer KRAS_G13D MGA 110 99 White 0.11 -0.71 0.81 1150.06 1.00 1393 102 91 8 FALSE 0.11
colorectal cancer KRAS_G13D MGA 110 99 Race:overall 0.04 -4.89 4.12 1578.86 1.00 1393 102 91 8 FALSE 0.01
colorectal cancer KRAS_G13D TCF3 110 60 White 0.36 -0.58 1.14 1212.83 1.00 1424 104 54 6 FALSE 0.36
colorectal cancer KRAS_G13D TCF3 110 60 Race:overall 0.34 -3.77 4.68 1533.71 1.00 1424 104 54 6 FALSE 0.06
colorectal cancer KRAS_G13D KMT2B 65 151 White 0.54 -0.07 1.09 929.79 1.00 733 49 135 16 FALSE 1.12
colorectal cancer KRAS_G13D KMT2B 65 151 Race:overall 0.43 -3.72 4.56 1557.04 1.00 733 49 135 16 FALSE 0.08
colorectal cancer KRAS_G13D TCF7L2 17 21 Asian -0.06 -1.11 0.87 1557.42 1.00 105 14 18 3 FALSE 0.04
colorectal cancer KRAS_G13D TCF7L2 20 13 Black -0.48 -2.07 0.49 1452.51 1.00 102 20 13 0 FALSE 0.33
colorectal cancer KRAS_G13D TCF7L2 6 21 Unknown -0.42 -2.16 0.60 1400.43 1.00 93 6 21 0 FALSE 0.27
colorectal cancer KRAS_G13D TCF7L2 113 239 White 0.19 -0.29 0.67 1405.70 1.00 1273 91 217 22 FALSE 0.36
colorectal cancer KRAS_G13D TCF7L2 156 294 Race:overall -0.20 -1.24 0.55 1455.94 1.00 1573 131 269 25 FALSE 0.18
colorectal cancer KRAS_G13D MSH3 62 76 White -0.18 -1.25 0.70 960.14 1.00 759 57 71 5 FALSE 0.14
colorectal cancer KRAS_G13D MSH3 62 76 Race:overall -0.10 -4.46 4.38 1244.86 1.00 759 57 71 5 FALSE 0.02
colorectal cancer KRAS_G13D ANKRD11 112 125 White 0.34 -0.34 0.95 1318.95 1.00 1386 100 113 12 FALSE 0.54
colorectal cancer KRAS_G13D ANKRD11 112 125 Race:overall 0.26 -4.69 4.66 1642.48 1.00 1386 100 113 12 FALSE 0.04
colorectal cancer KRAS_G13D PGR 110 52 White -0.90 -2.58 0.42 1140.13 1.00 1427 108 50 2 FALSE 0.61
colorectal cancer KRAS_G13D PGR 110 52 Race:overall -0.76 -4.89 4.02 1309.30 1.00 1427 108 50 2 FALSE 0.15
colorectal cancer KRAS_G13D PLCG2 111 64 White -0.21 -1.39 0.75 937.94 1.00 1418 107 60 4 FALSE 0.15
colorectal cancer KRAS_G13D PLCG2 111 64 Race:overall -0.13 -4.65 4.17 1427.01 1.00 1418 107 60 4 FALSE 0.02
colorectal cancer KRAS_G13D POLD1 112 95 White 0.42 -0.32 1.11 1126.69 1.00 1411 102 85 10 TRUE 0.60
colorectal cancer KRAS_G13D POLD1 112 95 Race:overall 0.34 -3.94 4.67 1452.33 1.00 1411 102 85 10 TRUE 0.06
colorectal cancer KRAS_G13D INHBA 110 43 White -5.94 -15.38 -0.92 921.94 1.00 1430 110 43 0 FALSE 0.78
colorectal cancer KRAS_G13D INHBA 110 43 Race:overall -4.17 -12.14 2.95 1106.00 1.00 1430 110 43 0 FALSE 0.59
colorectal cancer KRAS_G13D PREX2 64 78 White 0.02 -0.97 0.82 1131.47 1.00 758 58 72 6 FALSE 0.01
colorectal cancer KRAS_G13D PREX2 64 78 Race:overall 0.03 -4.28 4.62 1385.18 1.00 758 58 72 6 FALSE 0.00
colorectal cancer KRAS_G13D AMER1 20 12 Black 0.07 -1.95 1.20 1341.96 1.00 117 19 11 1 FALSE 0.03
colorectal cancer KRAS_G13D AMER1 129 135 White 0.57 -0.01 1.09 1432.17 1.00 1506 112 118 17 FALSE 1.37
colorectal cancer KRAS_G13D AMER1 149 147 Race:overall 0.29 -1.66 1.54 1411.61 1.00 1623 131 129 18 FALSE 0.15
colorectal cancer KRAS_G13D HLA-A 111 45 White 0.42 -0.65 1.38 1368.40 1.00 1439 106 40 5 FALSE 0.39
colorectal cancer KRAS_G13D HLA-A 111 45 Race:overall 0.39 -3.64 4.49 1567.39 1.00 1439 106 40 5 FALSE 0.07
colorectal cancer KRAS_G13D EPHA7 111 69 White -0.32 -1.54 0.68 1172.73 1.00 1416 107 65 4 FALSE 0.24
colorectal cancer KRAS_G13D EPHA7 111 69 Race:overall -0.24 -4.20 4.38 1521.93 1.00 1416 107 65 4 FALSE 0.04
colorectal cancer KRAS_G13D NCOA3 110 45 White -0.17 -1.48 0.91 1106.36 1.00 1434 107 42 3 TRUE 0.11
colorectal cancer KRAS_G13D NCOA3 110 45 Race:overall -0.23 -5.09 4.27 1611.86 1.00 1434 107 42 3 TRUE 0.04
colorectal cancer KRAS_G13D SLX4 61 47 White -0.75 -2.54 0.61 1494.87 1.00 780 59 45 2 FALSE 0.45
colorectal cancer KRAS_G13D SLX4 61 47 Race:overall -0.54 -5.34 3.98 1471.93 1.00 780 59 45 2 FALSE 0.09
colorectal cancer KRAS_G13D INPPL1 63 61 White 0.71 -0.13 1.48 832.26 1.00 779 55 53 8 FALSE 1.06
colorectal cancer KRAS_G13D INPPL1 63 61 Race:overall 0.63 -3.65 4.82 1320.27 1.00 779 55 53 8 FALSE 0.12
melanoma NRAS_Q61K SPEN 55 112 White -0.54 -1.60 0.40 1388.10 1.00 670 50 107 5 FALSE 0.53
melanoma NRAS_Q61K SPEN 55 112 Race:overall -0.43 -4.62 3.92 1530.67 1.00 670 50 107 5 FALSE 0.08
melanoma NRAS_Q61K KMT2C 56 142 White -0.66 -1.62 0.18 938.07 1.00 638 50 136 6 FALSE 0.80
melanoma NRAS_Q61K KMT2C 56 142 Race:overall -0.56 -4.88 3.52 1392.00 1.00 638 50 136 6 FALSE 0.11
melanoma NRAS_Q61K TP53 58 194 White 0.33 -0.30 0.91 1295.62 1.00 606 41 177 17 TRUE 0.54
melanoma NRAS_Q61K TP53 58 194 Race:overall 0.27 -3.85 4.58 1591.15 1.00 606 41 177 17 TRUE 0.05
melanoma NRAS_Q61K ATRX 56 101 White -0.45 -1.43 0.40 1275.47 1.00 675 51 96 5 TRUE 0.44
melanoma NRAS_Q61K ATRX 56 101 Race:overall -0.34 -4.65 4.07 1088.49 1.00 675 51 96 5 TRUE 0.06
melanoma NRAS_Q61K ATR 55 58 White -1.00 -2.70 0.31 1410.64 1.00 693 53 56 2 FALSE 0.69
melanoma NRAS_Q61K ATR 55 58 Race:overall -0.82 -4.61 3.62 1462.50 1.00 693 53 56 2 FALSE 0.17
melanoma NRAS_Q61K PDGFRA 57 75 White -1.23 -3.06 0.12 1099.41 1.00 699 55 73 2 TRUE 0.91
melanoma NRAS_Q61K PDGFRA 57 75 Race:overall -1.01 -5.25 3.76 1420.95 1.00 699 55 73 2 TRUE 0.20
melanoma NRAS_Q61K NSD1 55 48 White -0.78 -2.62 0.61 1529.58 1.00 702 53 46 2 FALSE 0.48
melanoma NRAS_Q61K NSD1 55 48 Race:overall -0.55 -4.47 4.55 1435.08 1.00 702 53 46 2 FALSE 0.10
melanoma NRAS_Q61K FLT4 55 86 White -1.41 -3.31 -0.10 955.70 1.00 673 53 84 2 TRUE 1.08
melanoma NRAS_Q61K FLT4 55 86 Race:overall -1.18 -5.07 3.14 1352.22 1.00 673 53 84 2 TRUE 0.26
melanoma NRAS_Q61K PTPRD 56 255 White -0.89 -1.60 -0.19 1162.07 1.00 586 48 247 8 FALSE 1.79
melanoma NRAS_Q61K PTPRD 59 273 Race:overall -0.80 -1.92 0.40 1473.94 1.00 637 50 264 9 FALSE 0.66
melanoma NRAS_Q61K RET 57 60 White -5.97 -14.85 -1.31 1115.89 1.00 708 57 60 0 TRUE 1.01
melanoma NRAS_Q61K RET 57 60 Race:overall -4.58 -11.93 2.18 1333.82 1.00 708 57 60 0 TRUE 0.72
melanoma NRAS_Q61K PIK3C2G 56 183 White -0.55 -1.34 0.17 1236.70 1.00 625 49 176 7 FALSE 0.80
melanoma NRAS_Q61K PIK3C2G 60 196 Race:overall -0.26 -1.58 1.61 1444.36 1.00 674 51 187 9 FALSE 0.12
melanoma NRAS_Q61K CREBBP 55 66 White -1.12 -2.99 0.26 1087.50 1.00 689 53 64 2 TRUE 0.76
melanoma NRAS_Q61K CREBBP 55 66 Race:overall -0.96 -5.33 3.47 1415.88 1.00 689 53 64 2 TRUE 0.19
melanoma NRAS_Q61K DOT1L 55 53 White -1.85 -4.52 -0.04 1428.33 1.00 698 54 52 1 FALSE 0.94
melanoma NRAS_Q61K DOT1L 55 53 Race:overall -1.51 -6.19 3.75 1527.99 1.00 698 54 52 1 FALSE 0.29
melanoma NRAS_Q61K PTPRS 55 64 White -2.03 -4.73 -0.28 1435.34 1.00 687 54 63 1 FALSE 1.09
melanoma NRAS_Q61K PTPRS 55 64 Race:overall -1.61 -6.14 3.59 1487.55 1.00 687 54 63 1 FALSE 0.32
melanoma NRAS_Q61K SMARCA4 55 69 White -0.64 -2.08 0.47 1416.38 1.00 684 52 66 3 FALSE 0.52
melanoma NRAS_Q61K SMARCA4 55 69 Race:overall -0.62 -4.82 3.56 1499.56 1.00 684 52 66 3 FALSE 0.12
melanoma NRAS_Q61K PTPRT 61 347 White 0.46 -0.04 0.99 1212.94 1.00 558 32 318 29 FALSE 1.12
melanoma NRAS_Q61K PTPRT 64 369 Race:overall 0.36 -0.97 1.42 1370.19 1.00 606 34 339 30 FALSE 0.26
melanoma NRAS_Q61K HGF 55 79 White -0.46 -1.74 0.55 1393.66 1.00 681 51 75 4 FALSE 0.38
melanoma NRAS_Q61K HGF 55 79 Race:overall -0.36 -4.62 4.51 1397.23 1.00 681 51 75 4 FALSE 0.06
melanoma NRAS_Q61K ALK 58 122 White -0.32 -1.14 0.47 282.55 1.01 667 51 115 7 TRUE 0.34
melanoma NRAS_Q61K ALK 58 122 Race:overall -0.31 -4.57 3.97 1482.90 1.00 667 51 115 7 TRUE 0.06
melanoma NRAS_Q61K BAP1 55 59 White -1.00 -2.80 0.31 922.43 1.00 689 53 57 2 TRUE 0.68
melanoma NRAS_Q61K BAP1 55 59 Race:overall -0.79 -4.74 4.02 1337.85 1.00 689 53 57 2 TRUE 0.15
melanoma NRAS_Q61K PTEN 57 77 White 0.05 -0.90 0.90 1201.57 1.00 688 51 71 6 TRUE 0.03
melanoma NRAS_Q61K PTEN 57 77 Race:overall 0.06 -4.19 4.50 1451.76 1.00 688 51 71 6 TRUE 0.01
melanoma NRAS_Q61K CTNNB1 58 54 White 0.66 -0.25 1.47 1070.81 1.00 712 51 47 7 TRUE 0.86
melanoma NRAS_Q61K CTNNB1 58 54 Race:overall 0.63 -4.19 5.03 1520.89 1.00 712 51 47 7 TRUE 0.12
melanoma NRAS_Q61K ARID1A 56 83 White 0.18 -0.79 0.96 1123.66 1.00 677 49 76 7 TRUE 0.17
melanoma NRAS_Q61K ARID1A 56 83 Race:overall 0.13 -4.22 4.20 1509.96 1.00 677 49 76 7 TRUE 0.02
melanoma NRAS_Q61K IKZF1 55 102 White -1.11 -2.42 0.02 466.62 1.01 671 52 99 3 TRUE 1.11
melanoma NRAS_Q61K IKZF1 55 102 Race:overall -0.97 -5.14 3.61 1096.63 1.01 671 52 99 3 TRUE 0.21
melanoma NRAS_Q61K TERT 59 581 White 1.31 0.59 2.08 1466.23 1.00 317 9 531 50 TRUE 3.34
melanoma NRAS_Q61K TERT 62 608 Race:overall 1.52 -0.39 3.67 1489.27 1.00 354 9 555 53 TRUE 0.92
melanoma NRAS_Q61K FAT1 55 139 White -0.06 -0.84 0.64 1483.22 1.00 643 46 130 9 FALSE 0.06
melanoma NRAS_Q61K FAT1 55 139 Race:overall -0.07 -4.13 4.18 1459.58 1.00 643 46 130 9 FALSE 0.01
melanoma NRAS_Q61K CIC 55 50 White -0.30 -1.76 0.83 1428.30 1.00 700 52 47 3 TRUE 0.19
melanoma NRAS_Q61K CIC 55 50 Race:overall -0.32 -4.26 4.10 1498.04 1.00 700 52 47 3 TRUE 0.06
melanoma NRAS_Q61K KDM6A 55 67 White -1.09 -2.90 0.20 937.04 1.00 723 53 65 2 FALSE 0.76
melanoma NRAS_Q61K KDM6A 55 67 Race:overall -0.87 -5.06 4.12 1169.47 1.00 723 53 65 2 FALSE 0.16
melanoma NRAS_Q61K POLE 57 68 White 0.73 -0.07 1.45 677.18 1.00 688 48 59 9 TRUE 1.20
melanoma NRAS_Q61K POLE 57 68 Race:overall 0.62 -4.28 4.93 1282.02 1.00 688 48 59 9 TRUE 0.11
melanoma NRAS_Q61K NOTCH2 55 59 White -0.50 -1.91 0.62 1350.06 1.00 694 52 56 3 TRUE 0.36
melanoma NRAS_Q61K NOTCH2 55 59 Race:overall -0.42 -5.08 4.04 1459.26 1.00 694 52 56 3 TRUE 0.08
melanoma NRAS_Q61K KMT2A 56 136 White -0.39 -1.29 0.34 1463.08 1.00 653 49 129 7 FALSE 0.43
melanoma NRAS_Q61K KMT2A 56 136 Race:overall -0.37 -4.75 3.99 1460.55 1.00 653 49 129 7 FALSE 0.07
melanoma NRAS_Q61K PAK7 57 202 White -0.49 -1.26 0.20 1336.75 1.00 600 47 192 10 FALSE 0.75
melanoma NRAS_Q61K PAK7 60 218 Race:overall -0.67 -2.34 0.42 1453.02 1.00 649 50 208 10 FALSE 0.44
melanoma NRAS_Q61K BRCA2 55 87 White -0.56 -1.74 0.40 636.66 1.01 681 51 83 4 TRUE 0.51
melanoma NRAS_Q61K BRCA2 55 87 Race:overall -0.46 -4.59 3.87 1367.29 1.00 681 51 83 4 TRUE 0.09
melanoma NRAS_Q61K NOTCH3 56 122 White -0.27 -1.24 0.55 1005.37 1.00 658 49 115 7 TRUE 0.26
melanoma NRAS_Q61K NOTCH3 56 122 Race:overall -0.15 -4.30 4.05 1434.12 1.00 658 49 115 7 TRUE 0.03
melanoma NRAS_Q61K NOTCH4 55 133 White -0.31 -1.16 0.44 1386.10 1.00 649 49 127 6 TRUE 0.34
melanoma NRAS_Q61K NOTCH4 59 148 Race:overall 0.27 -1.36 2.50 1399.92 1.00 698 50 139 9 TRUE 0.11
melanoma NRAS_Q61K CDKN2A 59 122 White 0.24 -0.47 0.89 180.00 1.01 658 48 111 11 TRUE 0.28
melanoma NRAS_Q61K CDKN2A 59 122 Race:overall 0.32 -3.86 4.70 1509.65 1.00 658 48 111 11 TRUE 0.06
melanoma NRAS_Q61K EPHB1 55 61 White -1.07 -2.85 0.28 911.85 1.00 691 53 59 2 FALSE 0.73
melanoma NRAS_Q61K EPHB1 55 61 Race:overall -0.91 -5.12 3.79 1193.33 1.00 691 53 59 2 FALSE 0.18
melanoma NRAS_Q61K IL7R 55 88 White -0.94 -2.31 0.19 370.08 1.01 675 52 85 3 FALSE 0.85
melanoma NRAS_Q61K IL7R 55 88 Race:overall -0.85 -5.26 3.30 1512.62 1.00 675 52 85 3 FALSE 0.18
melanoma NRAS_Q61K ATM 57 72 White -0.74 -2.10 0.36 1317.32 1.00 695 54 69 3 TRUE 0.61
melanoma NRAS_Q61K ATM 57 72 Race:overall -0.53 -4.92 4.20 1417.44 1.00 695 54 69 3 TRUE 0.10
melanoma NRAS_Q61K MAP2K1 55 54 White 0.24 -0.84 1.21 1458.97 1.00 697 50 49 5 TRUE 0.19
melanoma NRAS_Q61K MAP2K1 55 54 Race:overall 0.21 -4.05 4.59 1570.20 1.00 697 50 49 5 TRUE 0.04
melanoma NRAS_Q61K RB1 57 46 White 0.68 -0.29 1.55 1428.12 1.00 724 51 40 6 TRUE 0.84
melanoma NRAS_Q61K RB1 57 46 Race:overall 0.56 -3.97 4.60 1204.71 1.00 724 51 40 6 TRUE 0.11
melanoma NRAS_Q61K KMT2D 59 204 White 0.30 -0.26 0.91 722.64 1.00 626 42 187 17 FALSE 0.51
melanoma NRAS_Q61K KMT2D 62 216 Race:overall 0.30 -0.86 1.43 1417.84 1.00 676 44 198 18 FALSE 0.21
melanoma NRAS_Q61K APC 57 115 White -0.18 -1.03 0.63 1122.88 1.00 683 50 108 7 TRUE 0.17
melanoma NRAS_Q61K APC 57 115 Race:overall -0.21 -4.84 4.79 1713.55 1.00 683 50 108 7 TRUE 0.04
melanoma NRAS_Q61K ARID2 57 146 White 0.46 -0.21 1.08 1397.97 1.00 660 43 132 14 FALSE 0.80
melanoma NRAS_Q61K ARID2 57 146 Race:overall 0.38 -3.74 4.31 1397.00 1.00 660 43 132 14 FALSE 0.07
melanoma NRAS_Q61K MTOR 55 50 White -0.84 -2.67 0.45 1114.38 1.00 701 53 48 2 TRUE 0.54
melanoma NRAS_Q61K MTOR 55 50 Race:overall -0.63 -5.09 4.31 1487.01 1.00 701 53 48 2 TRUE 0.11
melanoma NRAS_Q61K NOTCH1 57 63 White -0.20 -1.38 0.74 1280.29 1.00 710 53 59 4 TRUE 0.15
melanoma NRAS_Q61K NOTCH1 57 63 Race:overall -0.21 -5.09 4.20 1508.12 1.00 710 53 59 4 TRUE 0.04
melanoma NRAS_Q61K NTRK1 55 48 White -1.78 -4.73 0.18 654.97 1.00 703 54 47 1 TRUE 0.83
melanoma NRAS_Q61K NTRK1 55 48 Race:overall -1.65 -6.15 3.05 1313.73 1.00 703 54 47 1 TRUE 0.33
melanoma NRAS_Q61K SETD2 55 77 White -1.29 -3.04 0.03 1302.15 1.00 684 53 75 2 FALSE 0.98
melanoma NRAS_Q61K SETD2 55 77 Race:overall -1.09 -5.55 3.94 1259.47 1.00 684 53 75 2 FALSE 0.21
melanoma NRAS_Q61K PBRM1 55 66 White -0.25 -1.46 0.73 1136.86 1.00 694 51 62 4 TRUE 0.19
melanoma NRAS_Q61K PBRM1 55 66 Race:overall -0.26 -4.80 3.94 1695.45 1.00 694 51 62 4 TRUE 0.05
melanoma NRAS_Q61K EPHA3 55 98 White 0.10 -0.86 0.93 51.37 1.07 676 48 91 7 FALSE 0.08
melanoma NRAS_Q61K EPHA3 55 98 Race:overall 0.07 -3.93 4.02 1404.94 1.00 676 48 91 7 FALSE 0.01
melanoma NRAS_Q61K KIT 57 53 White -5.95 -14.71 -1.08 1148.49 1.00 709 57 53 0 TRUE 0.85
melanoma NRAS_Q61K KIT 57 53 Race:overall -4.39 -11.25 2.13 979.52 1.00 709 57 53 0 TRUE 0.71
melanoma NRAS_Q61K KDR 57 125 White -1.90 -3.83 -0.56 957.48 1.00 662 55 123 2 TRUE 1.68
melanoma NRAS_Q61K KDR 57 125 Race:overall -1.68 -5.86 3.46 1399.86 1.00 662 55 123 2 TRUE 0.36
melanoma NRAS_Q61K CSF1R 57 55 White 0.22 -0.82 1.17 504.17 1.01 716 52 50 5 TRUE 0.17
melanoma NRAS_Q61K CSF1R 57 55 Race:overall 0.11 -4.44 4.20 1273.37 1.00 716 52 50 5 TRUE 0.02
melanoma NRAS_Q61K PTCH1 55 51 White -1.79 -4.72 0.08 1258.39 1.00 698 54 50 1 TRUE 0.86
melanoma NRAS_Q61K PTCH1 55 51 Race:overall -1.52 -5.96 3.42 1377.88 1.00 698 54 50 1 TRUE 0.30
melanoma NRAS_Q61K TET1 55 53 White 0.01 -1.20 1.09 1502.84 1.00 704 51 49 4 FALSE 0.01
melanoma NRAS_Q61K TET1 55 53 Race:overall -0.10 -4.58 4.25 1306.83 1.00 704 51 49 4 FALSE 0.02
melanoma NRAS_Q61K FGFR2 57 77 White -2.21 -4.93 -0.41 1305.06 1.00 696 56 76 1 TRUE 1.22
melanoma NRAS_Q61K FGFR2 57 77 Race:overall -1.86 -5.95 2.99 1399.29 1.00 696 56 76 1 TRUE 0.40
melanoma NRAS_Q61K TBX3 56 56 White -0.06 -1.26 0.85 1492.57 1.00 701 52 52 4 FALSE 0.04
melanoma NRAS_Q61K TBX3 56 56 Race:overall 0.04 -4.03 4.65 1575.66 1.00 701 52 52 4 FALSE 0.01
melanoma NRAS_Q61K DICER1 55 61 White -1.96 -4.93 -0.12 1489.03 1.00 697 54 60 1 TRUE 0.98
melanoma NRAS_Q61K DICER1 55 61 Race:overall -1.65 -6.27 3.04 1390.11 1.00 697 54 60 1 TRUE 0.32
melanoma NRAS_Q61K NTRK3 55 101 White -1.57 -3.27 -0.22 975.91 1.00 667 53 99 2 FALSE 1.37
melanoma NRAS_Q61K NTRK3 55 101 Race:overall -1.23 -5.16 3.19 1379.96 1.00 667 53 99 2 FALSE 0.27
melanoma NRAS_Q61K GRIN2A 58 280 White -0.44 -1.11 0.19 1126.67 1.00 582 45 267 13 FALSE 0.73
melanoma NRAS_Q61K GRIN2A 61 299 Race:overall -0.41 -1.59 0.86 1145.81 1.00 630 47 285 14 FALSE 0.32
melanoma NRAS_Q61K BRD4 55 59 White 0.17 -0.97 1.09 966.77 1.00 699 50 54 5 FALSE 0.13
melanoma NRAS_Q61K BRD4 55 59 Race:overall 0.22 -4.13 4.72 1325.11 1.00 699 50 54 5 FALSE 0.04
melanoma NRAS_Q61K ASXL1 55 51 White 0.04 -1.21 1.01 1366.19 1.00 702 51 47 4 TRUE 0.02
melanoma NRAS_Q61K ASXL1 55 51 Race:overall 0.02 -4.30 4.18 1435.83 1.00 702 51 47 4 TRUE 0.00
melanoma NRAS_Q61K EP300 55 67 White -2.05 -4.90 -0.25 1048.45 1.00 694 54 66 1 TRUE 1.09
melanoma NRAS_Q61K EP300 55 67 Race:overall -1.76 -6.29 3.05 1416.49 1.00 694 54 66 1 TRUE 0.37
melanoma NRAS_Q61K ERBB4 57 184 White -1.17 -2.18 -0.29 1521.79 1.00 633 52 179 5 TRUE 1.76
melanoma NRAS_Q61K ERBB4 57 184 Race:overall -1.00 -5.17 3.47 1432.27 1.00 633 52 179 5 TRUE 0.21
melanoma NRAS_Q61K MDC1 55 78 White -0.38 -1.52 0.54 467.52 1.01 685 51 74 4 FALSE 0.30
melanoma NRAS_Q61K MDC1 55 78 Race:overall -0.33 -4.62 4.17 1430.99 1.00 685 51 74 4 FALSE 0.06
melanoma NRAS_Q61K GNAQ 57 51 White -0.87 -2.75 0.49 1293.44 1.00 709 55 49 2 TRUE 0.52
melanoma NRAS_Q61K GNAQ 57 51 Race:overall -0.77 -5.22 3.97 1471.40 1.00 709 55 49 2 TRUE 0.14
melanoma NRAS_Q61K MED12 55 49 White -0.78 -2.61 0.51 1385.04 1.00 708 53 47 2 TRUE 0.47
melanoma NRAS_Q61K MED12 55 49 Race:overall -0.65 -4.89 4.03 1343.29 1.00 708 53 47 2 TRUE 0.12
melanoma NRAS_Q61K NF1 55 274 White -2.83 -4.96 -1.56 327.25 1.00 560 53 272 2 TRUE 3.25
melanoma NRAS_Q61K NF1 58 295 Race:overall -2.84 -5.06 -1.07 450.63 1.00 606 56 293 2 TRUE 2.25
melanoma NRAS_Q61K FLT1 55 116 White -1.24 -2.55 -0.16 1049.24 1.00 657 52 113 3 FALSE 1.38
melanoma NRAS_Q61K FLT1 55 116 Race:overall -1.11 -5.19 3.38 1251.96 1.00 657 52 113 3 FALSE 0.23
melanoma NRAS_Q61K RPTOR 55 45 White -0.20 -1.56 0.96 1316.79 1.00 704 52 42 3 FALSE 0.12
melanoma NRAS_Q61K RPTOR 55 45 Race:overall -0.13 -4.59 4.48 1564.29 1.00 704 52 42 3 FALSE 0.02
melanoma NRAS_Q61K SF3B1 55 79 White -2.26 -4.86 -0.41 1458.67 1.00 666 54 78 1 TRUE 1.27
melanoma NRAS_Q61K SF3B1 55 79 Race:overall -1.93 -6.11 2.82 1302.32 1.00 666 54 78 1 TRUE 0.44
melanoma NRAS_Q61K ROS1 55 238 White -1.04 -1.91 -0.36 223.57 1.02 595 49 232 6 TRUE 2.13
melanoma NRAS_Q61K ROS1 58 254 Race:overall -0.97 -2.15 0.34 1421.36 1.00 643 51 247 7 TRUE 0.93
melanoma NRAS_Q61K FLT3 57 77 White 0.06 -0.88 0.89 1342.20 1.00 693 51 71 6 TRUE 0.05
melanoma NRAS_Q61K FLT3 57 77 Race:overall 0.02 -4.34 3.97 1461.98 1.00 693 51 71 6 TRUE 0.00
melanoma NRAS_Q61K AXL 56 62 White 0.33 -0.62 1.17 1418.61 1.00 695 50 56 6 FALSE 0.33
melanoma NRAS_Q61K AXL 56 62 Race:overall 0.29 -3.82 4.66 1430.64 1.00 695 50 56 6 FALSE 0.05
melanoma NRAS_Q61K PIK3CG 55 91 White -1.49 -3.10 -0.34 137.97 1.02 678 53 89 2 FALSE 1.33
melanoma NRAS_Q61K PIK3CG 58 104 Race:overall -1.59 -4.09 0.18 224.81 1.01 727 56 102 2 FALSE 0.84
melanoma NRAS_Q61K EGFR 57 64 White -0.51 -1.84 0.44 89.08 1.04 705 54 61 3 TRUE 0.44
melanoma NRAS_Q61K EGFR 57 64 Race:overall -0.46 -4.49 3.86 1464.87 1.00 705 54 61 3 TRUE 0.10
melanoma NRAS_Q61K ARID1B 55 72 White -2.14 -4.92 -0.35 1331.50 1.00 690 54 71 1 TRUE 1.14
melanoma NRAS_Q61K ARID1B 55 72 Race:overall -1.83 -6.59 2.99 1447.50 1.00 690 54 71 1 TRUE 0.37
melanoma NRAS_Q61K GNA11 57 46 White -5.93 -15.83 -1.10 776.76 1.00 713 57 46 0 TRUE 0.80
melanoma NRAS_Q61K GNA11 57 46 Race:overall -4.38 -12.13 2.34 962.41 1.00 713 57 46 0 TRUE 0.67
melanoma NRAS_Q61K INSR 55 63 White -0.55 -1.97 0.59 1062.44 1.00 695 52 60 3 FALSE 0.40
melanoma NRAS_Q61K INSR 55 63 Race:overall -0.46 -4.93 4.11 1304.65 1.00 695 52 60 3 FALSE 0.08
melanoma NRAS_Q61K ERG 55 49 White -0.31 -2.03 0.90 387.75 1.01 706 52 46 3 FALSE 0.17
melanoma NRAS_Q61K ERG 55 49 Race:overall -0.27 -4.34 4.45 1519.85 1.00 706 52 46 3 FALSE 0.05
melanoma NRAS_Q61K MET 57 82 White -0.25 -1.26 0.59 1441.95 1.00 690 52 77 5 TRUE 0.22
melanoma NRAS_Q61K MET 57 82 Race:overall -0.21 -4.17 4.10 1405.97 1.00 690 52 77 5 TRUE 0.04
melanoma NRAS_Q61K BRAF 60 271 White -1.12 -1.96 0.04 77.57 1.04 513 51 262 9 TRUE 1.83
melanoma NRAS_Q61K BRAF 63 292 Race:overall -1.21 -2.82 0.14 217.81 1.02 551 54 283 9 TRUE 0.87
melanoma NRAS_Q61K TET2 55 86 White -0.92 -2.40 0.21 675.78 1.00 675 52 83 3 TRUE 0.77
melanoma NRAS_Q61K TET2 55 86 Race:overall -0.90 -5.41 3.40 1486.76 1.00 675 52 83 3 TRUE 0.18
melanoma NRAS_Q61K PDGFRB 55 60 White -0.43 -1.84 0.55 161.30 1.02 700 52 57 3 TRUE 0.29
melanoma NRAS_Q61K PDGFRB 55 60 Race:overall -0.43 -4.50 3.50 1365.10 1.00 700 52 57 3 TRUE 0.08
melanoma NRAS_Q61K CARD11 56 106 White -0.28 -1.25 0.53 1614.73 1.00 664 50 100 6 FALSE 0.28
melanoma NRAS_Q61K CARD11 56 106 Race:overall -0.21 -4.47 3.89 1334.79 1.00 664 50 100 6 FALSE 0.04
melanoma NRAS_Q61K CBL 55 75 White -0.76 -2.15 0.27 1054.82 1.00 680 52 72 3 TRUE 0.65
melanoma NRAS_Q61K CBL 55 75 Race:overall -0.68 -4.91 3.85 1480.17 1.00 680 52 72 3 TRUE 0.14
melanoma NRAS_Q61K TP63 56 160 White 0.00 -0.70 0.67 1396.86 1.00 630 45 149 11 FALSE 0.00
melanoma NRAS_Q61K TP63 56 160 Race:overall 0.06 -4.20 4.54 1594.17 1.00 630 45 149 11 FALSE 0.01
melanoma NRAS_Q61K GLI1 52 57 White -0.45 -1.81 0.65 1512.48 1.00 653 49 54 3 FALSE 0.33
melanoma NRAS_Q61K GLI1 52 57 Race:overall -0.39 -4.73 4.03 1531.82 1.00 653 49 54 3 FALSE 0.07
melanoma NRAS_Q61K ZFHX3 52 137 White -1.90 -3.73 -0.59 1312.28 1.00 622 50 135 2 FALSE 1.85
melanoma NRAS_Q61K ZFHX3 52 137 Race:overall -1.58 -6.03 3.07 1540.72 1.00 622 50 135 2 FALSE 0.35
melanoma NRAS_Q61K MGA 52 89 White 0.10 -0.76 0.90 1228.31 1.00 633 45 82 7 FALSE 0.09
melanoma NRAS_Q61K MGA 52 89 Race:overall 0.04 -4.44 4.37 1342.30 1.00 633 45 82 7 FALSE 0.01
melanoma NRAS_Q61K ANKRD11 52 72 White -1.24 -2.92 0.08 1186.04 1.00 645 50 70 2 FALSE 0.99
melanoma NRAS_Q61K ANKRD11 52 72 Race:overall -1.07 -5.44 3.85 1699.76 1.00 645 50 70 2 FALSE 0.21
melanoma NRAS_Q61K PGR 52 52 White -0.85 -2.58 0.46 1065.20 1.00 655 50 50 2 FALSE 0.54
melanoma NRAS_Q61K PGR 52 52 Race:overall -0.74 -5.14 3.62 1405.53 1.00 655 50 50 2 FALSE 0.14
melanoma NRAS_Q61K PLCG2 52 57 White -1.91 -4.81 -0.15 1095.83 1.00 649 51 56 1 FALSE 0.93
melanoma NRAS_Q61K PLCG2 52 57 Race:overall -1.55 -5.90 3.43 1400.39 1.00 649 51 56 1 FALSE 0.31
melanoma NRAS_Q61K EPHA7 52 148 White -0.16 -0.92 0.55 523.61 1.00 599 43 139 9 FALSE 0.17
melanoma NRAS_Q61K EPHA7 52 148 Race:overall -0.24 -4.36 3.82 1473.01 1.00 599 43 139 9 FALSE 0.05
melanoma NRAS_Q61R SPEN 75 112 White -0.94 -1.98 -0.04 1106.29 1.00 650 70 107 5 FALSE 1.22
melanoma NRAS_Q61R SPEN 75 112 Race:overall -0.74 -4.28 3.84 1431.77 1.00 650 70 107 5 FALSE 0.16
melanoma NRAS_Q61R KMT2C 76 142 White -0.38 -1.26 0.27 444.72 1.01 622 66 132 10 FALSE 0.52
melanoma NRAS_Q61R KMT2C 76 142 Race:overall -0.42 -4.71 3.70 1504.84 1.00 622 66 132 10 FALSE 0.08
melanoma NRAS_Q61R TP53 76 194 White -0.54 -1.20 0.10 1369.01 1.00 583 64 182 12 TRUE 0.98
thyroid cancer NRAS_Q61R TP53 42 58 White -0.19 -1.20 0.67 1025.90 1.00 273 36 52 6 TRUE 0.16
melanoma NRAS_Q61R TP53 76 194 Race:overall -0.42 -4.59 4.11 1579.67 1.00 583 64 182 12 TRUE 0.08
thyroid cancer NRAS_Q61R TP53 42 58 Race:overall -0.18 -4.21 4.03 1273.81 1.00 273 36 52 6 TRUE 0.03
melanoma NRAS_Q61R ATRX 76 101 White -0.60 -1.47 0.19 1276.48 1.00 656 70 95 6 TRUE 0.76
melanoma NRAS_Q61R ATRX 76 101 Race:overall -0.47 -4.42 3.81 1768.89 1.00 656 70 95 6 TRUE 0.09
melanoma NRAS_Q61R ATR 76 58 White -0.19 -1.23 0.66 1346.38 1.00 675 71 53 5 FALSE 0.16
melanoma NRAS_Q61R ATR 76 58 Race:overall -0.09 -4.35 4.12 1591.65 1.00 675 71 53 5 FALSE 0.02
melanoma NRAS_Q61R PDGFRA 76 75 White -2.52 -5.24 -0.78 1283.69 1.00 679 75 74 1 TRUE 1.50
melanoma NRAS_Q61R PDGFRA 76 75 Race:overall -2.19 -6.71 2.81 1503.01 1.00 679 75 74 1 TRUE 0.47
melanoma NRAS_Q61R NSD1 75 48 White -0.62 -2.08 0.56 1424.38 1.00 683 72 45 3 FALSE 0.44
melanoma NRAS_Q61R NSD1 75 48 Race:overall -0.46 -4.91 4.18 1467.96 1.00 683 72 45 3 FALSE 0.08
melanoma NRAS_Q61R FLT4 75 86 White -0.31 -1.09 0.51 28.74 1.06 658 68 79 7 TRUE 0.33
melanoma NRAS_Q61R FLT4 75 86 Race:overall -0.34 -4.31 3.94 1178.95 1.00 658 68 79 7 TRUE 0.07
melanoma NRAS_Q61R PTPRD 82 255 White -0.13 -0.64 0.38 1470.37 1.00 573 61 234 21 FALSE 0.21
melanoma NRAS_Q61R PTPRD 85 273 Race:overall 0.12 -1.12 1.89 1380.69 1.00 625 62 250 23 FALSE 0.06
melanoma NRAS_Q61R RET 76 60 White -1.31 -2.98 -0.01 1489.84 1.00 691 74 58 2 TRUE 1.06
melanoma NRAS_Q61R RET 76 60 Race:overall -1.07 -5.13 3.58 1436.73 1.00 691 74 58 2 TRUE 0.22
melanoma NRAS_Q61R PIK3C2G 77 183 White 0.05 -0.53 0.59 1340.68 1.00 614 60 166 17 FALSE 0.07
melanoma NRAS_Q61R PIK3C2G 79 196 Race:overall 0.12 -1.34 1.92 1419.91 1.00 664 61 178 18 FALSE 0.06
melanoma NRAS_Q61R CREBBP 75 66 White -0.35 -1.40 0.50 1201.27 1.00 672 70 61 5 TRUE 0.33
melanoma NRAS_Q61R CREBBP 75 66 Race:overall -0.29 -4.17 3.97 1525.54 1.00 672 70 61 5 TRUE 0.06
melanoma NRAS_Q61R DOT1L 75 53 White -0.07 -1.17 0.84 486.37 1.00 682 70 48 5 FALSE 0.05
melanoma NRAS_Q61R DOT1L 75 53 Race:overall -0.07 -4.24 4.11 1269.88 1.00 682 70 48 5 FALSE 0.01
melanoma NRAS_Q61R PTPRS 75 64 White -0.29 -1.36 0.57 1372.58 1.00 671 70 59 5 FALSE 0.25
melanoma NRAS_Q61R PTPRS 75 64 Race:overall -0.32 -4.71 4.11 1429.87 1.00 671 70 59 5 FALSE 0.06
melanoma NRAS_Q61R SMARCA4 75 69 White 0.22 -0.61 0.95 1565.26 1.00 669 67 61 8 FALSE 0.23
melanoma NRAS_Q61R SMARCA4 75 69 Race:overall 0.19 -3.98 4.87 1433.32 1.00 669 67 61 8 FALSE 0.03
melanoma NRAS_Q61R PTPRT 82 347 White -0.13 -0.60 0.34 1429.16 1.00 536 54 319 28 FALSE 0.23
melanoma NRAS_Q61R PTPRT 84 369 Race:overall -0.12 -1.80 1.54 1485.07 1.00 585 55 340 29 FALSE 0.06
melanoma NRAS_Q61R HGF 75 79 White -1.15 -2.62 -0.11 590.36 1.01 660 72 76 3 FALSE 1.12
melanoma NRAS_Q61R HGF 75 79 Race:overall -0.97 -5.28 3.27 1585.52 1.00 660 72 76 3 FALSE 0.20
melanoma NRAS_Q61R ALK 76 122 White -0.03 -0.72 0.61 1290.41 1.00 653 65 111 11 TRUE 0.03
melanoma NRAS_Q61R ALK 76 122 Race:overall -0.02 -4.45 4.47 1490.17 1.00 653 65 111 11 TRUE 0.00
melanoma NRAS_Q61R BAP1 75 59 White -2.27 -5.03 -0.45 1396.34 1.00 668 74 58 1 TRUE 1.25
melanoma NRAS_Q61R BAP1 75 59 Race:overall -1.92 -6.63 3.15 1371.88 1.00 668 74 58 1 TRUE 0.41
melanoma NRAS_Q61R PTEN 76 77 White -0.09 -0.95 0.73 1381.15 1.00 670 69 70 7 TRUE 0.08
melanoma NRAS_Q61R PTEN 76 77 Race:overall -0.08 -4.31 4.23 1666.78 1.00 670 69 70 7 TRUE 0.01
melanoma NRAS_Q61R CTNNB1 76 54 White -0.08 -1.12 0.79 1481.26 1.00 692 71 49 5 TRUE 0.06
melanoma NRAS_Q61R CTNNB1 76 54 Race:overall -0.10 -4.71 4.46 1512.33 1.00 692 71 49 5 TRUE 0.02
melanoma NRAS_Q61R ARID1A 75 83 White -1.22 -2.62 -0.08 1387.77 1.00 654 72 80 3 TRUE 1.25
melanoma NRAS_Q61R ARID1A 75 83 Race:overall -1.00 -5.22 3.93 1356.37 1.00 654 72 80 3 TRUE 0.20
melanoma NRAS_Q61R IKZF1 75 102 White -2.01 -3.64 -0.71 251.93 1.01 650 73 100 2 TRUE 1.96
melanoma NRAS_Q61R IKZF1 75 102 Race:overall -1.71 -5.87 3.25 1152.37 1.00 650 73 100 2 TRUE 0.38
melanoma NRAS_Q61R TERT 83 581 White 1.10 0.52 1.69 1170.61 1.00 311 15 513 68 TRUE 3.61
thyroid cancer NRAS_Q61R TERT 6 24 Asian 0.56 -0.42 1.52 1025.20 1.00 12 2 20 4 TRUE 0.63
thyroid cancer NRAS_Q61R TERT 8 11 Black 0.76 -0.19 1.95 949.17 1.00 11 3 6 5 TRUE 0.86
thyroid cancer NRAS_Q61R TERT 37 198 White 0.46 -0.26 1.11 830.95 1.00 129 12 173 25 TRUE 0.78
melanoma NRAS_Q61R TERT 86 608 Race:overall 1.30 -0.32 3.53 1448.97 1.00 348 15 537 71 TRUE 0.73
thyroid cancer NRAS_Q61R TERT 54 247 Race:overall 0.61 -0.25 1.46 845.93 1.00 160 17 210 37 TRUE 0.82
melanoma NRAS_Q61R FAT1 77 139 White -0.04 -0.66 0.58 1352.30 1.00 625 64 126 13 FALSE 0.04
melanoma NRAS_Q61R FAT1 77 139 Race:overall -0.02 -4.14 4.41 1582.55 1.00 625 64 126 13 FALSE 0.00
melanoma NRAS_Q61R CIC 75 50 White -2.13 -4.92 -0.31 1123.48 1.00 678 74 49 1 TRUE 1.14
melanoma NRAS_Q61R CIC 75 50 Race:overall -1.73 -5.86 3.29 1416.01 1.00 678 74 49 1 TRUE 0.36
melanoma NRAS_Q61R KDM6A 75 67 White -2.33 -4.89 -0.58 1411.62 1.00 702 74 66 1 FALSE 1.39
melanoma NRAS_Q61R KDM6A 75 67 Race:overall -1.96 -6.48 3.49 1335.95 1.00 702 74 66 1 FALSE 0.40
melanoma NRAS_Q61R POLE 75 68 White -0.38 -1.52 0.54 1365.52 1.00 666 70 63 5 TRUE 0.34
melanoma NRAS_Q61R POLE 75 68 Race:overall -0.41 -4.94 3.88 1466.43 1.00 666 70 63 5 TRUE 0.07
melanoma NRAS_Q61R NOTCH2 75 59 White -2.25 -4.95 -0.53 1016.16 1.00 672 74 58 1 TRUE 1.28
melanoma NRAS_Q61R NOTCH2 75 59 Race:overall -1.91 -6.25 3.01 1395.07 1.00 672 74 58 1 TRUE 0.42
melanoma NRAS_Q61R KMT2A 76 136 White 0.05 -0.61 0.66 1531.75 1.00 639 63 123 13 FALSE 0.06
melanoma NRAS_Q61R KMT2A 76 136 Race:overall 0.11 -4.43 4.36 1419.46 1.00 639 63 123 13 FALSE 0.02
melanoma NRAS_Q61R PAK7 76 202 White -0.20 -0.79 0.36 1117.67 1.00 586 61 187 15 FALSE 0.29
melanoma NRAS_Q61R PAK7 79 218 Race:overall 0.10 -1.34 2.27 1134.32 1.00 637 62 201 17 FALSE 0.04
melanoma NRAS_Q61R BRCA2 76 87 White -0.67 -1.70 0.19 1219.57 1.00 661 71 82 5 TRUE 0.78
melanoma NRAS_Q61R BRCA2 76 87 Race:overall -0.56 -4.59 4.17 1219.11 1.00 661 71 82 5 TRUE 0.11
melanoma NRAS_Q61R NOTCH3 75 122 White -1.30 -2.55 -0.35 1322.64 1.00 636 71 118 4 TRUE 1.80
melanoma NRAS_Q61R NOTCH3 75 122 Race:overall -1.14 -5.22 3.23 1548.81 1.00 636 71 118 4 TRUE 0.25
melanoma NRAS_Q61R NOTCH4 75 133 White -0.46 -1.22 0.25 1153.16 1.00 631 67 125 8 TRUE 0.63
melanoma NRAS_Q61R NOTCH4 78 148 Race:overall 0.87 -2.13 4.96 1473.87 1.00 681 67 137 11 TRUE 0.21
melanoma NRAS_Q61R CDKN2A 76 122 White -0.82 -1.85 0.05 447.92 1.01 636 70 116 6 TRUE 1.02
melanoma NRAS_Q61R CDKN2A 76 122 Race:overall -0.70 -4.94 4.25 1573.47 1.00 636 70 116 6 TRUE 0.14
melanoma NRAS_Q61R EPHB1 75 61 White 0.00 -1.00 0.79 1143.76 1.00 675 69 55 6 FALSE 0.00
melanoma NRAS_Q61R EPHB1 75 61 Race:overall 0.00 -4.24 4.03 1575.28 1.00 675 69 55 6 FALSE 0.00
melanoma NRAS_Q61R IL7R 75 88 White -0.43 -1.36 0.42 1057.89 1.00 658 69 82 6 FALSE 0.48
melanoma NRAS_Q61R IL7R 75 88 Race:overall -0.31 -4.33 3.92 1533.20 1.00 658 69 82 6 FALSE 0.06
melanoma NRAS_Q61R ATM 77 72 White -0.22 -1.23 0.63 1371.77 1.00 678 71 66 6 TRUE 0.20
melanoma NRAS_Q61R ATM 77 72 Race:overall -0.17 -4.77 3.93 1391.99 1.00 678 71 66 6 TRUE 0.03
melanoma NRAS_Q61R MAP2K1 75 54 White -1.22 -2.91 0.10 1018.56 1.00 674 73 52 2 TRUE 0.89
melanoma NRAS_Q61R MAP2K1 75 54 Race:overall -1.01 -5.47 3.52 1523.90 1.00 674 73 52 2 TRUE 0.20
melanoma NRAS_Q61R RB1 77 46 White 0.52 -0.41 1.29 1414.06 1.00 705 70 39 7 TRUE 0.63
melanoma NRAS_Q61R RB1 77 46 Race:overall 0.47 -4.05 4.62 1593.33 1.00 705 70 39 7 TRUE 0.09
melanoma NRAS_Q61R KMT2D 80 204 White -0.11 -0.72 0.40 114.60 1.03 605 63 187 17 FALSE 0.16
melanoma NRAS_Q61R KMT2D 82 216 Race:overall -0.32 -2.55 1.16 540.74 1.01 655 65 199 17 FALSE 0.14
melanoma NRAS_Q61R APC 77 115 White -0.97 -2.01 -0.08 1469.31 1.00 661 72 110 5 TRUE 1.31
melanoma NRAS_Q61R APC 77 115 Race:overall -0.84 -5.03 3.83 1432.36 1.00 661 72 110 5 TRUE 0.17
melanoma NRAS_Q61R ARID2 80 146 White -0.20 -0.86 0.40 1379.09 1.00 635 68 134 12 FALSE 0.27
melanoma NRAS_Q61R ARID2 80 146 Race:overall -0.17 -4.44 4.03 1617.23 1.00 635 68 134 12 FALSE 0.03
melanoma NRAS_Q61R MTOR 75 50 White -0.21 -1.44 0.67 107.39 1.03 683 71 46 4 TRUE 0.16
melanoma NRAS_Q61R MTOR 75 50 Race:overall -0.16 -4.24 4.26 1309.91 1.00 683 71 46 4 TRUE 0.03
melanoma NRAS_Q61R NOTCH1 76 63 White -1.37 -3.07 -0.09 1623.20 1.00 689 74 61 2 TRUE 1.12
melanoma NRAS_Q61R NOTCH1 76 63 Race:overall -1.09 -5.01 3.50 1574.61 1.00 689 74 61 2 TRUE 0.23
melanoma NRAS_Q61R NTRK1 75 48 White -0.66 -1.98 0.53 474.25 1.02 685 72 45 3 TRUE 0.54
melanoma NRAS_Q61R NTRK1 75 48 Race:overall -0.57 -4.48 4.03 1555.29 1.00 685 72 45 3 TRUE 0.11
melanoma NRAS_Q61R SETD2 75 77 White -0.25 -1.24 0.52 265.43 1.02 668 69 71 6 FALSE 0.23
melanoma NRAS_Q61R SETD2 75 77 Race:overall -0.23 -4.95 4.07 1609.73 1.00 668 69 71 6 FALSE 0.04
melanoma NRAS_Q61R PBRM1 75 66 White -0.55 -1.74 0.36 886.69 1.00 674 71 62 4 TRUE 0.51
melanoma NRAS_Q61R PBRM1 75 66 Race:overall -0.46 -4.79 4.05 1515.47 1.00 674 71 62 4 TRUE 0.09
melanoma NRAS_Q61R EPHA3 76 98 White -0.07 -0.84 0.65 803.27 1.00 657 67 89 9 FALSE 0.07
melanoma NRAS_Q61R EPHA3 76 98 Race:overall -0.07 -4.15 3.84 1383.38 1.00 657 67 89 9 FALSE 0.01
melanoma NRAS_Q61R KIT 76 53 White -6.38 -13.37 -1.64 79.04 1.05 690 76 53 0 TRUE 1.41
melanoma NRAS_Q61R KIT 76 53 Race:overall -5.22 -10.80 1.52 8.07 1.12 690 76 53 0 TRUE 1.03
melanoma NRAS_Q61R KDR 77 125 White 0.04 -0.69 0.70 1475.86 1.00 652 65 113 12 TRUE 0.04
melanoma NRAS_Q61R KDR 77 125 Race:overall 0.07 -4.26 4.17 1403.09 1.00 652 65 113 12 TRUE 0.01
melanoma NRAS_Q61R CSF1R 76 55 White -0.76 -2.17 0.31 997.28 1.00 695 73 52 3 TRUE 0.60
melanoma NRAS_Q61R CSF1R 76 55 Race:overall -0.64 -5.12 4.13 1409.96 1.00 695 73 52 3 TRUE 0.12
melanoma NRAS_Q61R PTCH1 75 51 White -1.19 -3.06 0.15 1335.04 1.00 679 73 49 2 TRUE 0.84
melanoma NRAS_Q61R PTCH1 75 51 Race:overall -0.97 -5.33 3.86 1468.29 1.00 679 73 49 2 TRUE 0.19
melanoma NRAS_Q61R TET1 75 53 White -0.74 -2.38 0.31 636.82 1.01 683 72 50 3 FALSE 0.60
melanoma NRAS_Q61R TET1 75 53 Race:overall -0.58 -4.73 4.03 1397.13 1.00 683 72 50 3 FALSE 0.11
melanoma NRAS_Q61R FGFR2 76 77 White -0.77 -1.95 0.20 1449.22 1.00 680 72 73 4 TRUE 0.80
melanoma NRAS_Q61R FGFR2 76 77 Race:overall -0.67 -4.72 3.67 1522.54 1.00 680 72 73 4 TRUE 0.13
melanoma NRAS_Q61R TBX3 75 56 White -1.30 -3.10 0.00 1366.02 1.00 680 73 54 2 FALSE 0.97
melanoma NRAS_Q61R TBX3 75 56 Race:overall -1.11 -5.54 3.37 1315.96 1.00 680 73 54 2 FALSE 0.22
melanoma NRAS_Q61R DICER1 77 61 White 0.65 -0.11 1.34 1276.10 1.00 684 67 51 10 TRUE 1.10
melanoma NRAS_Q61R DICER1 77 61 Race:overall 0.53 -3.66 4.88 1531.20 1.00 684 67 51 10 TRUE 0.10
melanoma NRAS_Q61R NTRK3 76 101 White -0.42 -1.26 0.31 1197.69 1.00 651 69 94 7 FALSE 0.52
melanoma NRAS_Q61R NTRK3 76 101 Race:overall -0.33 -4.50 3.98 1569.00 1.00 651 69 94 7 FALSE 0.06
melanoma NRAS_Q61R GRIN2A 80 280 White -0.37 -0.89 0.15 90.07 1.04 567 60 260 20 FALSE 0.70
melanoma NRAS_Q61R GRIN2A 82 299 Race:overall -0.62 -2.63 0.90 1277.39 1.00 615 62 279 20 FALSE 0.34
melanoma NRAS_Q61R BRD4 75 59 White -0.83 -2.25 0.27 1337.84 1.00 677 72 56 3 FALSE 0.71
melanoma NRAS_Q61R BRD4 75 59 Race:overall -0.71 -5.09 3.65 1344.97 1.00 677 72 56 3 FALSE 0.14
melanoma NRAS_Q61R ASXL1 75 51 White -2.14 -4.79 -0.38 1482.94 1.00 679 74 50 1 TRUE 1.18
melanoma NRAS_Q61R ASXL1 75 51 Race:overall -1.84 -6.31 3.18 1300.21 1.00 679 74 50 1 TRUE 0.39
melanoma NRAS_Q61R EP300 76 67 White -0.77 -2.26 0.41 11.60 1.20 675 73 64 3 TRUE 0.49
melanoma NRAS_Q61R EP300 76 67 Race:overall -0.70 -4.78 3.01 128.47 1.02 675 73 64 3 TRUE 0.16
melanoma NRAS_Q61R ERBB4 79 184 White -0.38 -1.06 0.22 874.97 1.00 619 66 171 13 TRUE 0.61
melanoma NRAS_Q61R ERBB4 79 184 Race:overall -0.36 -4.23 3.60 1424.30 1.00 619 66 171 13 TRUE 0.07
melanoma NRAS_Q61R MDC1 75 78 White -0.28 -1.25 0.52 1577.60 1.00 667 69 72 6 FALSE 0.27
melanoma NRAS_Q61R MDC1 75 78 Race:overall -0.25 -4.43 3.89 1511.51 1.00 667 69 72 6 FALSE 0.05
melanoma NRAS_Q61R GNAQ 76 51 White -6.01 -14.93 -1.22 788.87 1.00 688 76 51 0 TRUE 0.87
melanoma NRAS_Q61R GNAQ 76 51 Race:overall -4.41 -11.49 2.39 842.27 1.00 688 76 51 0 TRUE 0.69
melanoma NRAS_Q61R MED12 78 49 White 0.22 -0.74 1.03 1255.44 1.00 689 72 43 6 TRUE 0.19
melanoma NRAS_Q61R MED12 78 49 Race:overall 0.17 -4.23 4.13 1643.71 1.00 689 72 43 6 TRUE 0.03
melanoma NRAS_Q61R NF1 76 274 White -1.37 -2.18 -0.68 499.68 1.01 546 67 265 9 TRUE 3.52
melanoma NRAS_Q61R NF1 78 295 Race:overall -1.57 -3.72 -0.03 1517.22 1.00 593 69 286 9 TRUE 0.99
melanoma NRAS_Q61R FLT1 78 116 White 0.10 -0.60 0.70 1304.70 1.00 643 66 104 12 FALSE 0.11
melanoma NRAS_Q61R FLT1 78 116 Race:overall 0.12 -3.92 4.46 1535.21 1.00 643 66 104 12 FALSE 0.02
melanoma NRAS_Q61R RPTOR 75 45 White -1.05 -2.95 0.28 1379.08 1.00 683 73 43 2 FALSE 0.71
melanoma NRAS_Q61R RPTOR 75 45 Race:overall -0.84 -5.44 4.08 1253.16 1.00 683 73 43 2 FALSE 0.15
melanoma NRAS_Q61R SF3B1 75 79 White -0.15 -1.01 0.65 1219.25 1.00 652 68 72 7 TRUE 0.14
melanoma NRAS_Q61R SF3B1 75 79 Race:overall -0.10 -4.21 4.64 1393.04 1.00 652 68 72 7 TRUE 0.02
melanoma NRAS_Q61R ROS1 77 238 White -0.48 -1.10 0.07 891.17 1.00 581 63 224 14 TRUE 0.93
melanoma NRAS_Q61R ROS1 80 254 Race:overall -0.15 -1.50 1.94 1366.44 1.00 630 64 238 16 TRUE 0.07
melanoma NRAS_Q61R FLT3 76 77 White 0.10 -0.68 0.84 1318.78 1.00 676 68 69 8 TRUE 0.10
melanoma NRAS_Q61R FLT3 76 77 Race:overall 0.12 -4.24 3.96 1447.98 1.00 676 68 69 8 TRUE 0.02
melanoma NRAS_Q61R AXL 75 62 White -1.45 -3.16 -0.14 1064.73 1.01 672 73 60 2 FALSE 1.21
melanoma NRAS_Q61R AXL 75 62 Race:overall -1.16 -5.16 3.57 1513.15 1.00 672 73 60 2 FALSE 0.24
melanoma NRAS_Q61R PIK3CG 75 91 White -0.76 -1.79 0.11 1641.59 1.00 661 70 86 5 FALSE 0.92
melanoma NRAS_Q61R PIK3CG 77 104 Race:overall -1.07 -3.74 0.93 1479.67 1.00 711 72 99 5 FALSE 0.45
melanoma NRAS_Q61R EGFR 76 64 White -0.58 -1.82 0.42 1029.80 1.00 687 72 60 4 TRUE 0.52
melanoma NRAS_Q61R EGFR 76 64 Race:overall -0.46 -5.04 3.94 1396.04 1.00 687 72 60 4 TRUE 0.08
melanoma NRAS_Q61R ARID1B 75 72 White 0.02 -0.85 0.80 1529.64 1.00 676 68 65 7 TRUE 0.02
melanoma NRAS_Q61R ARID1B 75 72 Race:overall 0.03 -4.36 4.26 1394.53 1.00 676 68 65 7 TRUE 0.00
melanoma NRAS_Q61R GNA11 76 46 White -1.98 -4.55 -0.26 1220.37 1.00 695 75 45 1 TRUE 1.11
melanoma NRAS_Q61R GNA11 76 46 Race:overall -1.59 -6.12 3.75 1308.74 1.00 695 75 45 1 TRUE 0.32
melanoma NRAS_Q61R INSR 75 63 White 0.17 -0.80 0.98 1325.40 1.00 679 68 56 7 FALSE 0.15
melanoma NRAS_Q61R INSR 75 63 Race:overall 0.11 -4.33 3.93 1512.14 1.00 679 68 56 7 FALSE 0.02
melanoma NRAS_Q61R ERG 75 49 White -2.04 -4.75 -0.30 1164.51 1.01 684 74 48 1 FALSE 1.13
melanoma NRAS_Q61R ERG 75 49 Race:overall -1.83 -5.99 2.62 1484.32 1.00 684 74 48 1 FALSE 0.41
melanoma NRAS_Q61R MET 76 82 White -0.85 -2.01 0.09 776.25 1.01 670 72 78 4 TRUE 0.94
melanoma NRAS_Q61R MET 76 82 Race:overall -0.73 -4.90 3.38 1249.74 1.00 670 72 78 4 TRUE 0.15
melanoma NRAS_Q61R BRAF 76 271 White -2.73 -4.10 -1.60 1060.59 1.00 491 73 268 3 TRUE 4.86
thyroid cancer NRAS_Q61R BRAF 6 15 Asian -3.87 -6.96 -1.85 94.87 1.04 20 6 15 0 TRUE 2.19
thyroid cancer NRAS_Q61R BRAF 42 141 White -3.76 -6.63 -1.91 83.15 1.04 185 41 140 1 TRUE 2.67
melanoma NRAS_Q61R BRAF 78 292 Race:overall -2.75 -4.90 -0.75 1279.69 1.00 530 75 289 3 TRUE 2.21
thyroid cancer NRAS_Q61R BRAF 48 156 Race:overall -3.78 -6.74 -1.85 100.77 1.04 205 47 155 1 TRUE 2.42
melanoma NRAS_Q61R TET2 75 86 White -0.38 -1.27 0.43 721.56 1.01 658 69 80 6 TRUE 0.40
melanoma NRAS_Q61R TET2 75 86 Race:overall -0.31 -4.49 4.11 1543.81 1.00 658 69 80 6 TRUE 0.06
melanoma NRAS_Q61R PDGFRB 75 60 White -2.34 -5.26 -0.48 1538.76 1.00 678 74 59 1 TRUE 1.25
melanoma NRAS_Q61R PDGFRB 75 60 Race:overall -1.97 -6.30 2.74 1567.71 1.00 678 74 59 1 TRUE 0.41
melanoma NRAS_Q61R CARD11 75 106 White -1.13 -2.27 -0.21 1405.04 1.00 643 71 102 4 FALSE 1.56
melanoma NRAS_Q61R CARD11 75 106 Race:overall -1.01 -4.85 3.28 1448.30 1.00 643 71 102 4 FALSE 0.22
melanoma NRAS_Q61R CBL 75 75 White -0.48 -1.55 0.39 1417.48 1.00 662 70 70 5 TRUE 0.48
melanoma NRAS_Q61R CBL 75 75 Race:overall -0.32 -4.44 4.43 1310.26 1.00 662 70 70 5 TRUE 0.06
melanoma NRAS_Q61R TP63 78 160 White -0.02 -0.63 0.54 713.98 1.01 612 63 145 15 FALSE 0.03
melanoma NRAS_Q61R TP63 78 160 Race:overall -0.02 -4.42 4.42 1508.40 1.00 612 63 145 15 FALSE 0.00
melanoma NRAS_Q61R GLI1 73 57 White -0.85 -2.27 0.30 1370.13 1.00 632 70 54 3 FALSE 0.73
melanoma NRAS_Q61R GLI1 73 57 Race:overall -0.70 -4.86 3.50 1531.54 1.00 632 70 54 3 FALSE 0.14
melanoma NRAS_Q61R ZFHX3 74 137 White -0.62 -1.51 0.08 1300.10 1.00 606 66 129 8 FALSE 0.92
melanoma NRAS_Q61R ZFHX3 74 137 Race:overall -0.59 -4.62 3.13 1399.06 1.00 606 66 129 8 FALSE 0.13
melanoma NRAS_Q61R MGA 73 89 White -1.84 -3.76 -0.56 555.60 1.00 607 71 87 2 FALSE 1.64
melanoma NRAS_Q61R MGA 73 89 Race:overall -1.57 -5.66 3.12 1303.32 1.00 607 71 87 2 FALSE 0.35
melanoma NRAS_Q61R KMT2B 47 88 White -0.61 -1.61 0.20 1236.49 1.00 326 41 82 6 FALSE 0.73
melanoma NRAS_Q61R KMT2B 47 88 Race:overall -0.50 -4.53 4.21 1586.91 1.00 326 41 82 6 FALSE 0.10
melanoma NRAS_Q61R ANKRD11 73 72 White -0.72 -1.89 0.26 1402.09 1.00 626 69 68 4 FALSE 0.73
melanoma NRAS_Q61R ANKRD11 73 72 Race:overall -0.61 -4.46 3.76 1538.23 1.00 626 69 68 4 FALSE 0.12
melanoma NRAS_Q61R PGR 73 52 White -2.11 -4.84 -0.34 863.56 1.00 633 72 51 1 FALSE 1.14
melanoma NRAS_Q61R PGR 73 52 Race:overall -1.87 -6.21 2.90 1371.57 1.00 633 72 51 1 FALSE 0.39
melanoma NRAS_Q61R PLCG2 73 57 White -0.54 -1.92 0.47 275.61 1.01 631 69 53 4 FALSE 0.44
melanoma NRAS_Q61R PLCG2 73 57 Race:overall -0.48 -4.89 4.17 1545.88 1.00 631 69 53 4 FALSE 0.09
melanoma NRAS_Q61R PREX2 47 162 White -0.35 -1.09 0.27 1074.74 1.00 297 34 149 13 FALSE 0.51
melanoma NRAS_Q61R PREX2 49 174 Race:overall -0.57 -2.54 0.70 1469.32 1.00 321 36 161 13 FALSE 0.30
melanoma NRAS_Q61R EPHA7 73 148 White -1.31 -2.36 -0.44 702.41 1.00 574 68 143 5 FALSE 2.07
melanoma NRAS_Q61R EPHA7 73 148 Race:overall -1.15 -5.06 3.34 1423.65 1.00 574 68 143 5 FALSE 0.25
pancreatic cancer KRAS_G12R TP53 7 39 Black 0.76 0.22 1.49 816.86 1.00 16 0 32 7 TRUE 1.73
pancreatic cancer KRAS_G12R TP53 8 50 Unknown 0.66 0.06 1.26 901.10 1.00 30 2 44 6 TRUE 1.56
pancreatic cancer KRAS_G12R TP53 150 792 White 0.69 0.35 1.03 987.73 1.00 453 39 681 111 TRUE 3.82
pancreatic cancer KRAS_G12R TP53 171 944 Race:overall 0.67 0.18 1.18 682.83 1.00 544 43 816 128 TRUE 2.12
pancreatic cancer KRAS_G12R RNF43 143 66 White -0.02 -0.81 0.74 863.79 1.00 1031 135 58 8 TRUE 0.01
pancreatic cancer KRAS_G12R RNF43 143 66 Race:overall -0.01 -4.42 4.15 1593.88 1.00 1031 135 58 8 TRUE 0.00
pancreatic cancer KRAS_G12R ARID1A 143 104 White -1.16 -2.22 -0.29 1412.32 1.00 994 138 99 5 TRUE 1.68
pancreatic cancer KRAS_G12R ARID1A 145 120 Race:overall -1.46 -4.50 1.00 1535.23 1.00 1055 140 115 5 TRUE 0.56
pancreatic cancer KRAS_G12R KDM6A 143 56 White -0.18 -1.09 0.65 1224.58 1.00 1037 137 50 6 FALSE 0.16
pancreatic cancer KRAS_G12R KDM6A 143 56 Race:overall -0.22 -4.68 4.28 1597.35 1.00 1037 137 50 6 FALSE 0.04
pancreatic cancer KRAS_G12R CDKN2A 8 15 Unknown 0.44 -0.41 1.34 1358.27 1.00 62 6 13 2 TRUE 0.49
pancreatic cancer KRAS_G12R CDKN2A 153 250 White 0.43 0.04 0.80 1468.76 1.00 929 114 211 39 TRUE 1.65
pancreatic cancer KRAS_G12R CDKN2A 164 276 Race:overall 0.44 -0.34 1.21 1440.01 1.00 1058 122 234 42 TRUE 0.58
pancreatic cancer KRAS_G12R SMAD4 152 242 White 0.80 0.43 1.16 1542.80 1.00 939 104 194 48 TRUE 4.69
pancreatic cancer KRAS_G12R SMAD4 155 259 Race:overall 0.63 -0.87 1.99 1532.44 1.00 1000 106 210 49 TRUE 0.39
pancreatic cancer KRAS_G12R KMT2D 144 54 White -0.36 -1.49 0.52 1416.02 1.00 1042 139 49 5 FALSE 0.32
pancreatic cancer KRAS_G12R KMT2D 144 54 Race:overall -0.33 -5.15 4.62 1549.66 1.00 1042 139 49 5 FALSE 0.05
pancreatic cancer KRAS_G12R GNAS 150 53 White -0.11 -1.03 0.68 1275.46 1.00 1083 144 47 6 TRUE 0.09
pancreatic cancer KRAS_G12R GNAS 150 53 Race:overall -0.16 -4.68 4.17 1453.52 1.00 1083 144 47 6 TRUE 0.03
pancreatic cancer KRAS_G12R DAXX 143 46 White -6.22 -15.32 -1.46 1196.26 1.00 1044 143 46 0 TRUE 0.80
pancreatic cancer KRAS_G12R DAXX 143 46 Race:overall -4.58 -11.75 1.92 1244.24 1.00 1044 143 46 0 TRUE 0.74
pancreatic cancer KRAS_G12R MEN1 143 67 White -6.59 -15.78 -1.91 1171.48 1.00 1020 143 67 0 TRUE 0.97
pancreatic cancer KRAS_G12R MEN1 143 67 Race:overall -4.76 -11.74 2.97 1156.42 1.00 1020 143 67 0 TRUE 0.77
pancreatic cancer KRAS_Q61H TP53 51 792 White 0.59 0.10 1.30 16.39 1.09 480 12 753 39 TRUE 1.28
pancreatic cancer KRAS_Q61H TP53 60 944 Race:overall 0.55 -0.03 1.30 29.54 1.06 572 15 899 45 TRUE 1.03
pancreatic cancer KRAS_Q61H RNF43 49 66 White -5.82 -15.22 -0.80 1392.38 1.00 1117 49 66 0 TRUE 0.89
pancreatic cancer KRAS_Q61H RNF43 49 66 Race:overall -4.31 -11.50 2.47 1270.25 1.00 1117 49 66 0 TRUE 0.67
pancreatic cancer KRAS_Q61H ARID1A 50 104 White 0.15 -0.87 0.99 1538.63 1.00 1087 45 99 5 TRUE 0.12
pancreatic cancer KRAS_Q61H ARID1A 53 120 Race:overall 0.22 -1.49 2.11 1468.25 1.00 1148 47 114 6 TRUE 0.09
pancreatic cancer KRAS_Q61H KDM6A 49 56 White -0.23 -2.09 1.05 53.80 1.05 1127 47 54 2 FALSE 0.10
pancreatic cancer KRAS_Q61H KDM6A 49 56 Race:overall -0.23 -4.95 3.88 1330.42 1.01 1127 47 54 2 FALSE 0.04
pancreatic cancer KRAS_Q61H CDKN2A 50 250 White -0.20 -0.96 0.53 173.36 1.02 1001 42 242 8 TRUE 0.23
pancreatic cancer KRAS_Q61H CDKN2A 55 276 Race:overall -0.21 -1.14 0.65 364.30 1.01 1134 46 267 9 TRUE 0.18
pancreatic cancer KRAS_Q61H SMAD4 51 242 White 0.15 -0.54 0.77 1130.23 1.00 1002 41 232 10 TRUE 0.18
pancreatic cancer KRAS_Q61H SMAD4 54 259 Race:overall 0.36 -0.88 2.01 1355.29 1.00 1064 42 247 12 TRUE 0.21
pancreatic cancer KRAS_Q61H KMT2D 49 54 White -1.27 -4.22 0.56 1549.80 1.00 1133 48 53 1 FALSE 0.53
pancreatic cancer KRAS_Q61H KMT2D 49 54 Race:overall -0.99 -5.62 3.82 1501.00 1.00 1133 48 53 1 FALSE 0.18
pancreatic cancer KRAS_Q61H GNAS 50 53 White 0.28 -1.00 1.36 1323.26 1.00 1180 47 50 3 TRUE 0.18
pancreatic cancer KRAS_Q61H GNAS 50 53 Race:overall 0.11 -4.42 4.22 1164.46 1.00 1180 47 50 3 TRUE 0.02
pancreatic cancer KRAS_Q61H DAXX 49 46 White -5.12 -14.80 -0.34 406.46 1.01 1138 49 46 0 TRUE 0.74
pancreatic cancer KRAS_Q61H DAXX 49 46 Race:overall -3.76 -10.82 2.02 851.86 1.00 1138 49 46 0 TRUE 0.62
pancreatic cancer KRAS_Q61H MEN1 49 67 White -5.97 -13.93 -0.95 124.45 1.04 1114 49 67 0 TRUE 1.04
pancreatic cancer KRAS_Q61H MEN1 49 67 Race:overall -4.79 -11.34 2.38 34.87 1.09 1114 49 67 0 TRUE 0.74
colorectal cancer KRAS_G12S APC 10 156 Unknown 0.63 -0.34 1.68 1286.03 1.00 28 2 148 8 TRUE 0.65
colorectal cancer KRAS_G12S APC 47 1977 White 0.37 -0.25 1.08 1506.58 1.00 650 9 1939 38 TRUE 0.57
colorectal cancer KRAS_G12S APC 67 2530 Race:overall 0.45 -0.39 1.36 1563.27 1.00 813 12 2475 55 TRUE 0.51
colorectal cancer KRAS_G12A SPEN 22 55 Female -1.34 -4.07 0.49 364.07 1.02 985 22 55 0 FALSE 0.51
colorectal cancer KRAS_G12A SPEN 30 100 Male -0.88 -3.19 0.63 67.67 1.03 1135 28 98 2 FALSE 0.45
non-small cell lung cancer KRAS_G12A SPEN 56 56 Female 0.28 -0.78 1.47 70.52 1.05 2045 53 53 3 FALSE 0.19
non-small cell lung cancer KRAS_G12A SPEN 32 65 Male -0.03 -1.50 1.25 661.25 1.02 1479 31 64 1 FALSE 0.02
colorectal cancer KRAS_G12A SPEN 52 155 Sex:overall -1.10 -3.23 0.70 132.07 1.02 2120 50 153 2 FALSE 0.51
non-small cell lung cancer KRAS_G12A SPEN 88 121 Sex:overall 0.14 -1.34 1.51 269.15 1.02 3524 84 117 4 FALSE 0.07
non-small cell lung cancer KRAS_G12A KMT2C 56 113 Female -0.90 -2.49 0.24 1070.15 1.00 1976 55 112 1 FALSE 0.69
non-small cell lung cancer KRAS_G12A KMT2C 32 109 Male -0.69 -2.18 0.64 1032.24 1.00 1415 30 107 2 FALSE 0.50
non-small cell lung cancer KRAS_G12A KMT2C 88 222 Sex:overall -0.79 -2.39 0.53 1018.57 1.00 3391 85 219 3 FALSE 0.55
colorectal cancer KRAS_G12A TP53 25 796 Female -0.60 -1.18 0.00 1368.48 1.00 403 13 784 12 TRUE 1.33
colorectal cancer KRAS_G12A TP53 31 923 Male -0.55 -1.12 0.05 1419.05 1.00 490 14 906 17 TRUE 1.18
non-small cell lung cancer KRAS_G12A TP53 59 1120 Female -0.82 -1.30 -0.34 1660.00 1.00 1133 41 1102 18 TRUE 2.97
non-small cell lung cancer KRAS_G12A TP53 34 936 Male -0.87 -1.46 -0.33 1523.74 1.00 715 22 924 12 TRUE 2.55
colorectal cancer KRAS_G12A TP53 56 1719 Sex:overall -0.58 -1.25 0.10 1487.35 1.00 893 27 1690 29 TRUE 1.04
non-small cell lung cancer KRAS_G12A TP53 93 2056 Sex:overall -0.84 -1.66 -0.10 1532.31 1.00 1848 63 2026 30 TRUE 1.50
colorectal cancer KRAS_G12A ATRX 22 73 Female 0.02 -1.53 1.23 1411.92 1.00 969 20 71 2 TRUE 0.01
colorectal cancer KRAS_G12A ATRX 29 46 Male -0.12 -1.81 1.28 1201.62 1.00 1168 28 45 1 TRUE 0.05
non-small cell lung cancer KRAS_G12A ATRX 57 162 Female -0.06 -1.12 0.82 1468.87 1.00 1959 52 157 5 TRUE 0.04
non-small cell lung cancer KRAS_G12A ATRX 32 46 Male -1.16 -5.16 0.69 1166.15 1.00 1474 32 46 0 TRUE 0.30
colorectal cancer KRAS_G12A ATRX 51 119 Sex:overall -0.04 -1.91 1.56 1525.39 1.00 2137 48 116 3 TRUE 0.01
non-small cell lung cancer KRAS_G12A ATRX 89 208 Sex:overall -0.56 -3.26 1.54 1456.46 1.00 3433 84 203 5 TRUE 0.20
colorectal cancer KRAS_G12A ATR 22 30 Female -4.96 -12.51 -0.26 1460.32 1.00 1000 22 30 0 FALSE 0.94
colorectal cancer KRAS_G12A ATR 29 84 Male -5.01 -12.47 -0.60 1418.05 1.00 1149 29 84 0 FALSE 0.99
non-small cell lung cancer KRAS_G12A ATR 57 69 Female 0.40 -0.75 1.42 42.48 1.08 2028 53 65 4 FALSE 0.30
non-small cell lung cancer KRAS_G12A ATR 32 60 Male 0.20 -1.12 1.28 102.12 1.04 1461 31 59 1 FALSE 0.12
colorectal cancer KRAS_G12A ATR 51 114 Sex:overall -4.81 -11.82 -0.35 1388.88 1.00 2149 51 114 0 FALSE 0.97
non-small cell lung cancer KRAS_G12A ATR 89 129 Sex:overall 0.30 -0.92 1.42 76.57 1.04 3489 84 124 5 FALSE 0.19
colorectal cancer KRAS_G12A PDGFRA 25 28 Female -4.47 -11.33 -0.06 546.03 1.00 1099 25 28 0 TRUE 0.87
colorectal cancer KRAS_G12A PDGFRA 31 32 Male -4.43 -10.97 -0.03 742.02 1.00 1305 31 32 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A PDGFRA 58 69 Female -0.47 -2.09 0.76 1445.48 1.00 2092 57 68 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A PDGFRA 33 79 Male -0.25 -1.70 0.99 1432.11 1.00 1503 31 77 2 TRUE 0.14
colorectal cancer KRAS_G12A PDGFRA 56 60 Sex:overall -4.41 -11.21 0.05 603.38 1.00 2404 56 60 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A PDGFRA 91 148 Sex:overall -0.35 -1.94 1.06 1448.69 1.00 3595 88 145 3 TRUE 0.18
colorectal cancer KRAS_G12A FBXW7 25 137 Female 0.63 -0.20 1.32 1234.98 1.00 1012 20 132 5 TRUE 1.03
colorectal cancer KRAS_G12A FBXW7 32 202 Male 0.65 -0.07 1.33 1038.28 1.00 1164 24 194 8 TRUE 1.18
non-small cell lung cancer KRAS_G12A FBXW7 58 39 Female -1.56 -5.21 0.64 1130.13 1.00 2121 58 39 0 TRUE 0.52
non-small cell lung cancer KRAS_G12A FBXW7 33 47 Male -1.12 -4.35 0.98 963.46 1.00 1531 32 46 1 TRUE 0.40
colorectal cancer KRAS_G12A FBXW7 57 339 Sex:overall 0.64 -0.20 1.49 1108.24 1.00 2176 44 326 13 TRUE 0.82
non-small cell lung cancer KRAS_G12A FBXW7 91 86 Sex:overall -1.32 -4.63 0.81 1157.40 1.00 3652 90 85 1 TRUE 0.47
colorectal cancer KRAS_G12A MAP3K1 22 39 Female -1.33 -4.37 0.68 827.30 1.00 994 22 39 0 FALSE 0.51
colorectal cancer KRAS_G12A MAP3K1 29 53 Male -1.17 -3.83 0.77 689.53 1.00 1158 28 52 1 FALSE 0.47
non-small cell lung cancer KRAS_G12A MAP3K1 56 39 Female -0.07 -1.99 1.29 931.11 1.00 2055 55 38 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A MAP3K1 32 28 Male -0.02 -1.89 1.46 919.42 1.00 1491 31 27 1 FALSE 0.01
colorectal cancer KRAS_G12A MAP3K1 51 92 Sex:overall -1.25 -4.13 0.69 690.19 1.00 2152 50 91 1 FALSE 0.49
non-small cell lung cancer KRAS_G12A MAP3K1 88 67 Sex:overall -0.05 -2.03 1.47 1030.17 1.00 3546 86 65 2 FALSE 0.02
colorectal cancer KRAS_G12A NSD1 22 35 Female -3.36 -11.35 -0.15 3.93 1.27 998 22 35 0 FALSE 0.52
colorectal cancer KRAS_G12A NSD1 29 51 Male -3.35 -11.43 -0.18 3.93 1.27 1162 29 51 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A NSD1 56 50 Female 0.59 -0.72 1.68 1156.31 1.00 2045 53 47 3 FALSE 0.48
non-small cell lung cancer KRAS_G12A NSD1 32 40 Male 0.46 -0.94 1.62 1230.35 1.00 1479 31 39 1 FALSE 0.33
colorectal cancer KRAS_G12A NSD1 51 86 Sex:overall -3.32 -11.12 -0.17 3.85 1.28 2160 51 86 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A NSD1 88 90 Sex:overall 0.52 -0.87 1.70 1181.29 1.00 3524 84 86 4 FALSE 0.37
colorectal cancer KRAS_G12A FLT4 22 70 Female -0.74 -2.71 0.70 1157.62 1.00 969 21 69 1 TRUE 0.40
colorectal cancer KRAS_G12A FLT4 29 69 Male -0.75 -2.71 0.63 1141.54 1.00 1144 28 68 1 TRUE 0.41
non-small cell lung cancer KRAS_G12A FLT4 57 47 Female 0.74 -0.46 1.96 61.00 1.04 2050 53 43 4 TRUE 0.59
non-small cell lung cancer KRAS_G12A FLT4 32 55 Male -0.63 -5.05 1.19 1286.79 1.00 1464 32 55 0 TRUE 0.16
colorectal cancer KRAS_G12A FLT4 51 139 Sex:overall -0.75 -2.76 0.73 1226.63 1.00 2113 49 137 2 TRUE 0.40
non-small cell lung cancer KRAS_G12A FLT4 89 102 Sex:overall 0.10 -2.35 1.75 1417.21 1.00 3514 85 98 4 TRUE 0.03
colorectal cancer KRAS_G12A PTPRD 22 48 Female 0.40 -1.01 1.43 1022.39 1.00 987 21 47 1 FALSE 0.29
colorectal cancer KRAS_G12A PTPRD 29 55 Male 0.53 -0.70 1.54 1074.71 1.00 1167 26 52 3 FALSE 0.45
non-small cell lung cancer KRAS_G12A PTPRD 57 235 Female 0.17 -0.56 0.85 913.07 1.00 1905 51 229 6 FALSE 0.21
non-small cell lung cancer KRAS_G12A PTPRD 32 156 Male 0.33 -0.40 1.13 707.75 1.01 1384 26 150 6 FALSE 0.41
colorectal cancer KRAS_G12A PTPRD 51 103 Sex:overall 0.47 -0.84 1.51 1195.53 1.00 2154 47 99 4 FALSE 0.35
non-small cell lung cancer KRAS_G12A PTPRD 89 391 Sex:overall 0.24 -0.55 1.09 825.28 1.00 3289 77 379 12 FALSE 0.25
colorectal cancer KRAS_G12A RET 25 36 Female -3.73 -11.98 0.49 14.42 1.14 1092 25 36 0 TRUE 0.58
colorectal cancer KRAS_G12A RET 31 29 Male -3.73 -11.81 0.43 15.41 1.14 1305 31 29 0 TRUE 0.59
non-small cell lung cancer KRAS_G12A RET 58 55 Female -0.44 -2.26 0.92 1131.49 1.00 2102 57 54 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A RET 33 38 Male -0.39 -2.27 1.09 929.46 1.00 1541 32 37 1 TRUE 0.19
colorectal cancer KRAS_G12A RET 56 65 Sex:overall -3.68 -11.40 0.52 14.59 1.14 2397 56 65 0 TRUE 0.59
non-small cell lung cancer KRAS_G12A RET 91 93 Sex:overall -0.41 -2.33 1.10 1166.60 1.00 3643 89 91 2 TRUE 0.20
colorectal cancer KRAS_G12A KDM5A 22 31 Female -4.89 -11.97 -0.36 881.97 1.00 999 22 31 0 FALSE 0.98
colorectal cancer KRAS_G12A KDM5A 29 65 Male -4.94 -12.03 -0.41 821.20 1.01 1155 29 65 0 FALSE 1.01
non-small cell lung cancer KRAS_G12A KDM5A 56 37 Female 0.43 -0.97 1.60 1205.30 1.00 2057 54 35 2 FALSE 0.29
non-small cell lung cancer KRAS_G12A KDM5A 32 36 Male 0.34 -1.29 1.57 1233.99 1.00 1486 31 35 1 FALSE 0.19
colorectal cancer KRAS_G12A KDM5A 51 96 Sex:overall -4.81 -11.73 -0.36 832.48 1.00 2154 51 96 0 FALSE 0.99
non-small cell lung cancer KRAS_G12A KDM5A 88 73 Sex:overall 0.37 -1.31 1.73 1135.95 1.00 3543 85 70 3 FALSE 0.20
colorectal cancer KRAS_G12A PIK3C2G 22 30 Female 0.53 -0.94 1.68 1218.55 1.00 970 21 29 1 FALSE 0.35
colorectal cancer KRAS_G12A PIK3C2G 29 57 Male 0.65 -0.64 1.68 1328.98 1.00 1129 26 54 3 FALSE 0.56
non-small cell lung cancer KRAS_G12A PIK3C2G 56 70 Female 0.67 -0.30 1.52 1213.54 1.00 2016 52 66 4 FALSE 0.86
non-small cell lung cancer KRAS_G12A PIK3C2G 32 61 Male 0.60 -0.50 1.51 1120.16 1.00 1459 30 59 2 FALSE 0.64
colorectal cancer KRAS_G12A PIK3C2G 51 87 Sex:overall 0.58 -1.03 1.85 1359.51 1.00 2099 47 83 4 FALSE 0.37
non-small cell lung cancer KRAS_G12A PIK3C2G 88 131 Sex:overall 0.66 -0.36 1.64 1138.47 1.00 3475 82 125 6 FALSE 0.68
non-small cell lung cancer KRAS_G12A TSHR 56 47 Female -0.12 -2.03 1.20 1026.84 1.00 2048 55 46 1 TRUE 0.05
non-small cell lung cancer KRAS_G12A TSHR 32 22 Male 0.04 -1.75 1.49 1030.22 1.00 1497 31 21 1 TRUE 0.02
non-small cell lung cancer KRAS_G12A TSHR 88 69 Sex:overall -0.02 -1.90 1.42 949.24 1.00 3545 86 67 2 TRUE 0.01
colorectal cancer KRAS_G12A CREBBP 22 81 Female -1.10 -3.22 0.32 356.38 1.01 967 21 80 1 TRUE 0.68
colorectal cancer KRAS_G12A CREBBP 29 107 Male -1.12 -3.25 0.27 337.13 1.01 1125 28 106 1 TRUE 0.72
non-small cell lung cancer KRAS_G12A CREBBP 56 82 Female -0.23 -1.45 0.80 61.04 1.07 2018 53 79 3 TRUE 0.16
non-small cell lung cancer KRAS_G12A CREBBP 32 60 Male -0.54 -2.86 0.69 306.75 1.00 1462 32 60 0 TRUE 0.24
colorectal cancer KRAS_G12A CREBBP 51 188 Sex:overall -1.10 -3.24 0.37 363.93 1.01 2092 49 186 2 TRUE 0.67
non-small cell lung cancer KRAS_G12A CREBBP 88 142 Sex:overall -0.37 -2.00 0.78 173.24 1.02 3480 85 139 3 TRUE 0.22
non-small cell lung cancer KRAS_G12A BRIP1 56 36 Female 0.33 -1.24 1.56 868.35 1.00 2057 55 35 1 TRUE 0.19
non-small cell lung cancer KRAS_G12A BRIP1 32 34 Male 0.53 -0.95 1.74 564.66 1.00 1486 30 32 2 TRUE 0.34
non-small cell lung cancer KRAS_G12A BRIP1 88 70 Sex:overall 0.42 -1.21 1.82 923.99 1.00 3543 85 67 3 TRUE 0.23
colorectal cancer KRAS_G12A AXIN2 22 48 Female 0.53 -0.78 1.57 1362.20 1.00 990 21 47 1 TRUE 0.43
colorectal cancer KRAS_G12A AXIN2 29 67 Male 0.69 -0.39 1.68 858.02 1.00 1150 25 63 4 TRUE 0.72
non-small cell lung cancer KRAS_G12A AXIN2 56 31 Female -0.68 -3.32 1.03 558.35 1.01 2061 55 30 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A AXIN2 32 31 Male -0.92 -4.08 0.85 299.54 1.02 1487 32 31 0 TRUE 0.34
colorectal cancer KRAS_G12A AXIN2 51 115 Sex:overall 0.62 -0.60 1.72 1289.66 1.00 2140 46 110 5 TRUE 0.52
non-small cell lung cancer KRAS_G12A AXIN2 88 62 Sex:overall -0.77 -3.35 1.02 526.43 1.01 3548 87 61 1 TRUE 0.30
colorectal cancer KRAS_G12A DOT1L 23 30 Female 0.11 -1.77 1.84 614.41 1.01 1001 21 28 2 FALSE 0.04
colorectal cancer KRAS_G12A DOT1L 29 54 Male -0.85 -4.14 0.99 1274.29 1.00 1161 29 54 0 FALSE 0.20
non-small cell lung cancer KRAS_G12A DOT1L 56 46 Female -1.09 -4.20 0.70 1412.46 1.00 2046 56 46 0 FALSE 0.37
non-small cell lung cancer KRAS_G12A DOT1L 32 61 Male -0.22 -2.14 1.20 1404.97 1.00 1461 30 59 2 FALSE 0.10
colorectal cancer KRAS_G12A DOT1L 52 84 Sex:overall -0.33 -2.71 1.49 1351.47 1.00 2162 50 82 2 FALSE 0.12
non-small cell lung cancer KRAS_G12A DOT1L 88 107 Sex:overall -0.62 -3.11 1.15 1513.14 1.00 3507 86 105 2 FALSE 0.24
non-small cell lung cancer KRAS_G12A PTPRS 56 43 Female -1.06 -3.87 0.73 489.42 1.01 2039 55 42 1 FALSE 0.43
non-small cell lung cancer KRAS_G12A PTPRS 32 37 Male -1.27 -4.58 0.58 580.82 1.00 1480 32 37 0 FALSE 0.46
non-small cell lung cancer KRAS_G12A PTPRS 88 80 Sex:overall -1.14 -4.03 0.75 550.14 1.00 3519 87 79 1 FALSE 0.44
colorectal cancer KRAS_G12A SMARCA4 23 77 Female 0.58 -0.27 1.38 287.89 1.01 967 20 74 3 FALSE 0.72
colorectal cancer KRAS_G12A SMARCA4 30 92 Male 0.59 -0.28 1.38 279.56 1.01 1139 26 88 4 FALSE 0.76
non-small cell lung cancer KRAS_G12A SMARCA4 56 163 Female -0.47 -1.67 0.41 350.25 1.01 1945 54 161 2 FALSE 0.41
non-small cell lung cancer KRAS_G12A SMARCA4 32 150 Male -0.18 -1.31 0.76 1000.38 1.01 1379 28 146 4 FALSE 0.14
colorectal cancer KRAS_G12A SMARCA4 53 169 Sex:overall 0.58 -0.28 1.42 314.57 1.01 2106 46 162 7 FALSE 0.71
non-small cell lung cancer KRAS_G12A SMARCA4 88 313 Sex:overall -0.32 -1.53 0.72 616.02 1.01 3324 82 307 6 FALSE 0.24
colorectal cancer KRAS_G12A PTPRT 22 71 Female -0.83 -2.66 0.44 127.13 1.02 963 21 70 1 FALSE 0.56
colorectal cancer KRAS_G12A PTPRT 29 114 Male -0.91 -2.87 0.29 54.27 1.04 1107 28 113 1 FALSE 0.61
non-small cell lung cancer KRAS_G12A PTPRT 58 205 Female -0.14 -1.00 0.62 747.71 1.00 1926 53 200 5 FALSE 0.13
non-small cell lung cancer KRAS_G12A PTPRT 32 146 Male -0.14 -1.06 0.70 766.36 1.00 1400 29 143 3 FALSE 0.12
colorectal cancer KRAS_G12A PTPRT 51 185 Sex:overall -0.87 -2.72 0.43 109.72 1.03 2070 49 183 2 FALSE 0.56
non-small cell lung cancer KRAS_G12A PTPRT 90 351 Sex:overall -0.14 -1.08 0.75 888.23 1.00 3326 82 343 8 FALSE 0.11
colorectal cancer KRAS_G12A HGF 22 14 Female -4.53 -12.37 0.27 854.39 1.00 1015 22 14 0 FALSE 0.77
colorectal cancer KRAS_G12A HGF 29 42 Male -4.57 -12.28 0.04 716.55 1.01 1166 29 42 0 FALSE 0.79
non-small cell lung cancer KRAS_G12A HGF 56 108 Female 0.03 -1.00 0.95 334.00 1.01 1993 53 105 3 FALSE 0.02
non-small cell lung cancer KRAS_G12A HGF 32 83 Male 0.03 -1.01 1.02 350.37 1.01 1443 30 81 2 FALSE 0.02
colorectal cancer KRAS_G12A HGF 51 56 Sex:overall -4.41 -11.94 0.23 766.42 1.01 2181 51 56 0 FALSE 0.78
non-small cell lung cancer KRAS_G12A HGF 88 191 Sex:overall 0.03 -1.04 1.08 343.47 1.01 3436 83 186 5 FALSE 0.02
colorectal cancer KRAS_G12A BLM 22 26 Female -4.45 -11.10 -0.17 350.15 1.00 1004 22 26 0 TRUE 0.89
colorectal cancer KRAS_G12A BLM 29 44 Male -4.49 -11.29 -0.23 360.26 1.00 1167 29 44 0 TRUE 0.89
colorectal cancer KRAS_G12A BLM 51 70 Sex:overall -4.41 -10.90 -0.12 344.73 1.00 2171 51 70 0 TRUE 0.89
colorectal cancer KRAS_G12A PIK3CA 25 244 Female 0.05 -0.70 0.74 1097.38 1.00 913 19 238 6 TRUE 0.05
colorectal cancer KRAS_G12A PIK3CA 32 267 Male 0.01 -0.75 0.70 1183.03 1.00 1103 26 261 6 TRUE 0.01
non-small cell lung cancer KRAS_G12A PIK3CA 59 141 Female -0.02 -1.01 0.80 508.02 1.00 2025 55 137 4 TRUE 0.01
non-small cell lung cancer KRAS_G12A PIK3CA 33 101 Male -0.05 -1.09 0.79 478.25 1.01 1478 31 99 2 TRUE 0.04
colorectal cancer KRAS_G12A PIK3CA 57 511 Sex:overall 0.03 -0.74 0.80 1195.17 1.00 2016 45 499 12 TRUE 0.03
non-small cell lung cancer KRAS_G12A PIK3CA 92 242 Sex:overall -0.03 -1.12 0.82 604.52 1.00 3503 86 236 6 TRUE 0.02
non-small cell lung cancer KRAS_G12A GATA3 56 40 Female -1.14 -4.20 0.76 1293.65 1.00 2054 56 40 0 FALSE 0.41
non-small cell lung cancer KRAS_G12A GATA3 32 26 Male -0.86 -3.60 1.08 1250.34 1.00 1494 31 25 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A GATA3 88 66 Sex:overall -0.99 -3.93 0.97 1194.19 1.00 3548 87 65 1 FALSE 0.38
colorectal cancer KRAS_G12A ESR1 22 26 Female -1.23 -4.38 0.86 1152.98 1.00 1004 22 26 0 TRUE 0.42
colorectal cancer KRAS_G12A ESR1 29 46 Male -0.94 -3.65 0.95 978.11 1.00 1161 28 45 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A ESR1 56 30 Female -4.79 -11.82 -0.34 120.43 1.02 2064 56 30 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A ESR1 32 26 Male -4.77 -11.79 -0.25 101.98 1.02 1492 32 26 0 TRUE 0.91
colorectal cancer KRAS_G12A ESR1 51 72 Sex:overall -1.05 -3.93 1.11 1083.21 1.00 2165 50 71 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A ESR1 88 56 Sex:overall -4.74 -11.73 -0.29 112.62 1.02 3556 88 56 0 TRUE 0.91
colorectal cancer KRAS_G12A ALK 25 55 Female -1.39 -4.10 0.50 994.99 1.00 1078 24 54 1 TRUE 0.61
colorectal cancer KRAS_G12A ALK 31 60 Male -1.57 -4.63 0.35 938.38 1.00 1283 31 60 0 TRUE 0.64
non-small cell lung cancer KRAS_G12A ALK 58 90 Female -1.82 -4.65 0.01 1292.84 1.00 2071 57 89 1 TRUE 0.92
non-small cell lung cancer KRAS_G12A ALK 33 79 Male -2.02 -5.22 -0.10 1269.93 1.00 1502 33 79 0 TRUE 0.82
colorectal cancer KRAS_G12A ALK 56 115 Sex:overall -1.46 -4.33 0.51 1021.23 1.00 2361 55 114 1 TRUE 0.62
non-small cell lung cancer KRAS_G12A ALK 91 169 Sex:overall -1.91 -4.82 0.06 1373.07 1.00 3573 90 168 1 TRUE 0.87
colorectal cancer KRAS_G12A RNF43 22 140 Female -2.18 -5.01 -0.32 1167.49 1.00 926 21 139 1 TRUE 1.17
colorectal cancer KRAS_G12A RNF43 29 127 Male -2.43 -5.54 -0.55 1013.75 1.00 1109 29 127 0 TRUE 1.24
colorectal cancer KRAS_G12A RNF43 51 267 Sex:overall -2.27 -5.16 -0.39 1121.99 1.00 2035 50 266 1 TRUE 1.18
non-small cell lung cancer KRAS_G12A U2AF1 56 52 Female 1.08 0.00 2.12 618.25 1.00 2042 53 49 3 FALSE 1.42
non-small cell lung cancer KRAS_G12A U2AF1 33 26 Male 1.31 0.14 2.41 874.48 1.00 1496 30 23 3 FALSE 1.62
non-small cell lung cancer KRAS_G12A U2AF1 89 78 Sex:overall 1.20 -0.04 2.27 958.46 1.00 3538 83 72 6 FALSE 1.33
non-small cell lung cancer KRAS_G12A LATS1 56 41 Female -0.96 -3.72 0.88 1219.08 1.00 2040 55 40 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A LATS1 32 27 Male -1.11 -4.32 0.90 1006.96 1.00 1486 32 27 0 FALSE 0.40
non-small cell lung cancer KRAS_G12A LATS1 88 68 Sex:overall -1.02 -3.86 0.96 1141.89 1.00 3526 87 67 1 FALSE 0.39
non-small cell lung cancer KRAS_G12A LATS2 56 30 Female -4.68 -11.37 -0.11 505.42 1.00 2051 56 30 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A LATS2 32 31 Male -4.67 -11.40 -0.13 525.43 1.00 1483 32 31 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A LATS2 88 61 Sex:overall -4.60 -11.29 -0.05 494.89 1.00 3534 88 61 0 FALSE 0.92
colorectal cancer KRAS_G12A PTEN 25 80 Female -1.33 -2.97 0.32 5.17 1.25 1068 24 79 1 TRUE 0.77
colorectal cancer KRAS_G12A PTEN 31 105 Male -1.36 -3.10 0.22 4.76 1.27 1254 30 104 1 TRUE 0.80
non-small cell lung cancer KRAS_G12A PTEN 58 60 Female -0.77 -2.75 0.70 1231.80 1.00 2097 57 59 1 TRUE 0.43
non-small cell lung cancer KRAS_G12A PTEN 33 76 Male -0.76 -2.63 0.71 1351.71 1.00 1506 32 75 1 TRUE 0.43
colorectal cancer KRAS_G12A PTEN 56 185 Sex:overall -1.35 -3.04 0.31 5.02 1.25 2322 54 183 2 TRUE 0.76
non-small cell lung cancer KRAS_G12A PTEN 91 136 Sex:overall -0.75 -2.84 0.89 1345.56 1.00 3603 89 134 2 TRUE 0.38
colorectal cancer KRAS_G12A BCOR 22 59 Female -1.52 -4.85 0.41 1012.10 1.01 982 22 59 0 FALSE 0.58
colorectal cancer KRAS_G12A BCOR 29 53 Male -1.23 -3.87 0.67 1034.46 1.00 1157 28 52 1 FALSE 0.55
non-small cell lung cancer KRAS_G12A BCOR 56 103 Female -0.96 -2.99 0.43 1554.05 1.00 1998 55 102 1 FALSE 0.57
non-small cell lung cancer KRAS_G12A BCOR 32 31 Male -0.51 -2.62 1.35 1378.80 1.00 1490 31 30 1 FALSE 0.21
colorectal cancer KRAS_G12A BCOR 51 112 Sex:overall -1.36 -4.09 0.61 1032.17 1.00 2139 50 111 1 FALSE 0.56
non-small cell lung cancer KRAS_G12A BCOR 88 134 Sex:overall -0.74 -3.15 1.33 1391.59 1.00 3488 86 132 2 FALSE 0.30
colorectal cancer KRAS_G12A CTNNB1 25 74 Female -0.34 -1.70 0.83 904.88 1.00 1057 23 72 2 TRUE 0.21
colorectal cancer KRAS_G12A CTNNB1 31 89 Male -0.44 -1.91 0.73 855.71 1.00 1250 30 88 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A CTNNB1 58 74 Female -0.38 -2.74 0.95 21.54 1.08 2085 56 72 2 TRUE 0.17
non-small cell lung cancer KRAS_G12A CTNNB1 33 47 Male -0.42 -2.73 0.99 23.73 1.07 1530 32 46 1 TRUE 0.18
colorectal cancer KRAS_G12A CTNNB1 56 163 Sex:overall -0.38 -1.90 0.89 878.12 1.00 2307 53 160 3 TRUE 0.23
non-small cell lung cancer KRAS_G12A CTNNB1 91 121 Sex:overall -0.40 -2.73 1.05 23.98 1.07 3615 88 118 3 TRUE 0.16
colorectal cancer KRAS_G12A ARID1A 22 149 Female -0.82 -2.17 0.24 1051.88 1.00 932 21 148 1 TRUE 0.72
colorectal cancer KRAS_G12A ARID1A 29 166 Male -0.69 -1.94 0.40 940.75 1.00 1085 26 163 3 TRUE 0.62
non-small cell lung cancer KRAS_G12A ARID1A 56 132 Female -0.73 -2.10 0.37 1345.18 1.00 1971 54 130 2 TRUE 0.61
non-small cell lung cancer KRAS_G12A ARID1A 33 152 Male -0.74 -2.10 0.40 1404.25 1.00 1382 31 150 2 TRUE 0.60
colorectal cancer KRAS_G12A ARID1A 51 315 Sex:overall -0.76 -2.09 0.35 1051.97 1.00 2017 47 311 4 TRUE 0.63
non-small cell lung cancer KRAS_G12A ARID1A 89 284 Sex:overall -0.71 -2.18 0.60 1295.76 1.00 3353 85 280 4 TRUE 0.48
colorectal cancer KRAS_G12A PIK3R1 22 44 Female -1.70 -5.23 0.44 1341.89 1.00 988 22 44 0 TRUE 0.61
colorectal cancer KRAS_G12A PIK3R1 29 72 Male -1.43 -4.22 0.46 1114.41 1.00 1148 28 71 1 TRUE 0.63
non-small cell lung cancer KRAS_G12A PIK3R1 56 30 Female -4.46 -11.42 -0.11 1223.03 1.00 2062 56 30 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A PIK3R1 32 25 Male -4.43 -11.20 0.15 1249.00 1.00 1494 32 25 0 TRUE 0.87
colorectal cancer KRAS_G12A PIK3R1 51 116 Sex:overall -1.53 -4.46 0.61 1203.25 1.00 2136 50 115 1 TRUE 0.61
non-small cell lung cancer KRAS_G12A PIK3R1 88 55 Sex:overall -4.40 -11.19 0.01 1217.26 1.00 3556 88 55 0 TRUE 0.88
colorectal cancer KRAS_G12A IKZF1 22 42 Female -4.57 -11.79 -0.42 677.89 1.00 990 22 42 0 TRUE 0.90
colorectal cancer KRAS_G12A IKZF1 29 44 Male -4.55 -11.68 -0.37 679.43 1.00 1162 29 44 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A IKZF1 56 48 Female 0.17 -1.50 1.38 830.08 1.00 2045 55 47 1 TRUE 0.09
non-small cell lung cancer KRAS_G12A IKZF1 32 34 Male 0.38 -1.26 1.71 726.17 1.00 1487 30 32 2 TRUE 0.23
colorectal cancer KRAS_G12A IKZF1 51 86 Sex:overall -4.52 -11.62 -0.35 629.28 1.00 2152 51 86 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A IKZF1 88 82 Sex:overall 0.26 -1.43 1.63 989.80 1.00 3532 85 79 3 TRUE 0.13
colorectal cancer KRAS_G12A TERT 22 40 Female -1.37 -4.12 0.65 639.19 1.00 991 22 40 0 TRUE 0.54
colorectal cancer KRAS_G12A TERT 29 58 Male -1.20 -3.87 0.73 624.14 1.00 1156 28 57 1 TRUE 0.51
non-small cell lung cancer KRAS_G12A TERT 56 87 Female 0.06 -1.15 1.07 1522.11 1.00 2010 54 85 2 TRUE 0.04
non-small cell lung cancer KRAS_G12A TERT 32 79 Male 0.22 -0.88 1.26 843.63 1.00 1447 29 76 3 TRUE 0.17
colorectal cancer KRAS_G12A TERT 51 98 Sex:overall -1.26 -4.00 0.80 757.50 1.00 2147 50 97 1 TRUE 0.52
non-small cell lung cancer KRAS_G12A TERT 88 166 Sex:overall 0.16 -1.12 1.28 1394.37 1.00 3457 83 161 5 TRUE 0.10
colorectal cancer KRAS_G12A FAT1 22 97 Female 0.10 -1.08 0.94 1310.24 1.00 959 20 95 2 FALSE 0.08
colorectal cancer KRAS_G12A FAT1 30 130 Male 0.17 -0.88 0.97 1006.94 1.00 1128 26 126 4 FALSE 0.14
non-small cell lung cancer KRAS_G12A FAT1 56 155 Female -0.37 -1.49 0.52 1196.79 1.00 1953 52 151 4 FALSE 0.35
non-small cell lung cancer KRAS_G12A FAT1 32 150 Male -0.66 -2.11 0.30 356.93 1.01 1388 31 149 1 FALSE 0.53
colorectal cancer KRAS_G12A FAT1 52 227 Sex:overall 0.14 -0.97 1.00 1020.26 1.00 2087 46 221 6 FALSE 0.10
non-small cell lung cancer KRAS_G12A FAT1 88 305 Sex:overall -0.50 -1.87 0.63 1044.26 1.00 3341 83 300 5 FALSE 0.37
colorectal cancer KRAS_G12A FGFR4 22 19 Female -0.86 -4.17 1.25 1164.77 1.00 1012 22 19 0 TRUE 0.28
colorectal cancer KRAS_G12A FGFR4 29 34 Male -0.62 -3.40 1.30 1237.56 1.00 1174 28 33 1 TRUE 0.21
colorectal cancer KRAS_G12A FGFR4 51 53 Sex:overall -0.70 -3.77 1.37 1170.71 1.00 2186 50 52 1 TRUE 0.23
colorectal cancer KRAS_G12A CIC 22 58 Female -0.20 -1.63 0.95 1097.69 1.00 984 21 57 1 TRUE 0.11
colorectal cancer KRAS_G12A CIC 30 79 Male -0.16 -1.56 0.98 1157.07 1.00 1143 28 77 2 TRUE 0.09
non-small cell lung cancer KRAS_G12A CIC 56 43 Female 0.44 -1.11 1.69 1331.36 1.00 2054 53 40 3 TRUE 0.27
non-small cell lung cancer KRAS_G12A CIC 32 49 Male -0.60 -4.20 1.18 1260.63 1.00 1478 32 49 0 TRUE 0.15
colorectal cancer KRAS_G12A CIC 52 137 Sex:overall -0.17 -1.62 1.05 1165.68 1.00 2127 49 134 3 TRUE 0.09
non-small cell lung cancer KRAS_G12A CIC 88 92 Sex:overall -0.04 -2.67 1.76 1480.12 1.00 3532 85 89 3 TRUE 0.01
colorectal cancer KRAS_G12A KDM6A 22 31 Female -0.19 -2.67 1.35 1227.78 1.00 1000 22 31 0 FALSE 0.06
colorectal cancer KRAS_G12A KDM6A 29 31 Male 0.24 -1.67 1.74 961.71 1.00 1177 27 29 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A KDM6A 56 28 Female 0.46 -1.24 1.74 835.18 1.00 2066 55 27 1 FALSE 0.25
non-small cell lung cancer KRAS_G12A KDM6A 33 33 Male 0.65 -0.92 1.92 810.54 1.00 1488 31 31 2 FALSE 0.43
colorectal cancer KRAS_G12A KDM6A 51 62 Sex:overall 0.04 -2.31 1.61 1085.46 1.00 2177 49 60 2 FALSE 0.01
non-small cell lung cancer KRAS_G12A KDM6A 89 61 Sex:overall 0.56 -1.09 1.93 1008.47 1.00 3554 86 58 3 FALSE 0.33
colorectal cancer KRAS_G12A NCOR1 22 54 Female -0.26 -1.76 1.03 1356.88 1.00 981 21 53 1 FALSE 0.15
colorectal cancer KRAS_G12A NCOR1 29 81 Male -0.20 -1.54 1.00 1374.84 1.00 1146 27 79 2 FALSE 0.12
non-small cell lung cancer KRAS_G12A NCOR1 56 53 Female 0.68 -0.38 1.58 1267.93 1.00 2048 53 50 3 FALSE 0.73
non-small cell lung cancer KRAS_G12A NCOR1 32 51 Male 0.64 -0.50 1.57 1263.81 1.00 1472 30 49 2 FALSE 0.65
colorectal cancer KRAS_G12A NCOR1 51 135 Sex:overall -0.23 -1.77 1.05 1396.01 1.00 2127 48 132 3 FALSE 0.13
non-small cell lung cancer KRAS_G12A NCOR1 88 104 Sex:overall 0.66 -0.52 1.70 1157.74 1.00 3520 83 99 5 FALSE 0.61
colorectal cancer KRAS_G12A POLE 22 59 Female 0.15 -1.41 1.52 900.00 1.00 982 19 56 3 TRUE 0.08
colorectal cancer KRAS_G12A POLE 29 82 Male -0.91 -4.87 0.72 925.25 1.00 1141 29 82 0 TRUE 0.25
non-small cell lung cancer KRAS_G12A POLE 56 67 Female -0.40 -2.07 0.84 1381.88 1.00 2031 55 66 1 TRUE 0.22
non-small cell lung cancer KRAS_G12A POLE 32 69 Male -0.16 -1.62 1.10 1476.44 1.00 1454 30 67 2 TRUE 0.09
colorectal cancer KRAS_G12A POLE 51 141 Sex:overall -0.39 -2.92 1.27 1297.18 1.00 2123 48 138 3 TRUE 0.14
non-small cell lung cancer KRAS_G12A POLE 88 136 Sex:overall -0.27 -1.93 1.09 1429.64 1.00 3485 85 133 3 TRUE 0.14
non-small cell lung cancer KRAS_G12A CUL3 56 34 Female -1.08 -4.33 1.01 533.95 1.00 2063 55 33 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A CUL3 32 43 Male -1.51 -5.33 0.62 722.93 1.00 1478 32 43 0 FALSE 0.44
non-small cell lung cancer KRAS_G12A CUL3 88 77 Sex:overall -1.25 -4.72 1.12 686.41 1.00 3541 87 76 1 FALSE 0.41
colorectal cancer KRAS_G12A ABL1 25 34 Female -4.85 -14.77 -0.37 74.53 1.05 1095 25 34 0 TRUE 0.77
colorectal cancer KRAS_G12A ABL1 31 39 Male -4.87 -14.71 -0.50 75.66 1.05 1300 31 39 0 TRUE 0.77
colorectal cancer KRAS_G12A ABL1 56 73 Sex:overall -4.83 -14.72 -0.41 74.47 1.05 2395 56 73 0 TRUE 0.76
colorectal cancer KRAS_G12A FOXP1 22 24 Female -0.88 -4.17 0.87 15.35 1.11 1005 22 24 0 FALSE 0.27
colorectal cancer KRAS_G12A FOXP1 29 46 Male -0.61 -3.29 0.92 14.63 1.11 1164 28 45 1 FALSE 0.22
colorectal cancer KRAS_G12A FOXP1 51 70 Sex:overall -0.73 -3.70 0.99 16.65 1.10 2169 50 69 1 FALSE 0.24
non-small cell lung cancer KRAS_G12A NOTCH2 56 62 Female -5.00 -11.64 -0.73 1200.29 1.00 2023 56 62 0 TRUE 1.09
non-small cell lung cancer KRAS_G12A NOTCH2 32 53 Male -4.99 -11.55 -0.62 1246.98 1.00 1465 32 53 0 TRUE 1.08
non-small cell lung cancer KRAS_G12A NOTCH2 88 115 Sex:overall -4.95 -11.29 -0.62 1189.62 1.00 3488 88 115 0 TRUE 1.08
non-small cell lung cancer KRAS_G12A DDR2 56 49 Female -4.76 -12.18 -0.73 73.28 1.04 2042 56 49 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A DDR2 32 49 Male -4.76 -12.38 -0.68 63.59 1.05 1469 32 49 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A DDR2 88 98 Sex:overall -4.71 -12.19 -0.74 71.06 1.04 3511 88 98 0 TRUE 0.92
colorectal cancer KRAS_G12A TGFBR2 22 53 Female -1.31 -3.91 0.52 980.26 1.00 979 21 52 1 TRUE 0.58
colorectal cancer KRAS_G12A TGFBR2 29 61 Male -1.56 -4.82 0.34 916.08 1.00 1147 29 61 0 TRUE 0.64
non-small cell lung cancer KRAS_G12A TGFBR2 56 35 Female -5.46 -13.60 -0.27 45.88 1.09 2060 56 35 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A TGFBR2 32 21 Male -5.44 -13.46 -0.11 48.16 1.09 1497 32 21 0 TRUE 0.91
colorectal cancer KRAS_G12A TGFBR2 51 114 Sex:overall -1.42 -4.17 0.57 1062.32 1.00 2126 50 113 1 TRUE 0.60
non-small cell lung cancer KRAS_G12A TGFBR2 88 56 Sex:overall -5.41 -13.41 -0.18 45.42 1.09 3557 88 56 0 TRUE 0.91
colorectal cancer KRAS_G12A SMO 25 32 Female -4.04 -10.73 -0.15 180.50 1.01 1096 25 32 0 TRUE 0.88
colorectal cancer KRAS_G12A SMO 31 39 Male -4.04 -10.65 -0.26 181.71 1.01 1299 31 39 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A SMO 58 39 Female -0.19 -2.01 1.14 958.29 1.00 2120 57 38 1 TRUE 0.09
non-small cell lung cancer KRAS_G12A SMO 33 36 Male -0.13 -2.02 1.37 1079.55 1.00 1540 32 35 1 TRUE 0.05
colorectal cancer KRAS_G12A SMO 56 71 Sex:overall -4.02 -10.63 -0.20 191.17 1.01 2395 56 71 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A SMO 91 75 Sex:overall -0.16 -2.03 1.32 962.10 1.00 3660 89 73 2 TRUE 0.06
colorectal cancer KRAS_G12A KMT2A 22 69 Female -4.65 -10.36 -1.31 38.08 1.06 977 22 69 0 FALSE 1.24
colorectal cancer KRAS_G12A KMT2A 29 79 Male -4.66 -10.32 -1.19 35.94 1.06 1142 29 79 0 FALSE 1.24
non-small cell lung cancer KRAS_G12A KMT2A 56 64 Female -1.38 -3.90 0.39 779.39 1.00 2033 55 63 1 FALSE 0.66
non-small cell lung cancer KRAS_G12A KMT2A 32 50 Male -1.55 -4.55 0.34 628.03 1.00 1470 32 50 0 FALSE 0.66
colorectal cancer KRAS_G12A KMT2A 51 148 Sex:overall -4.62 -10.25 -1.24 36.58 1.06 2119 51 148 0 FALSE 1.25
non-small cell lung cancer KRAS_G12A KMT2A 88 114 Sex:overall -1.45 -4.20 0.51 683.27 1.00 3503 87 113 1 FALSE 0.65
colorectal cancer KRAS_G12A JAK3 25 33 Female -1.01 -4.20 1.01 1384.69 1.00 1097 25 33 0 TRUE 0.34
colorectal cancer KRAS_G12A JAK3 31 30 Male -0.75 -3.73 1.08 1408.46 1.00 1305 30 29 1 TRUE 0.26
non-small cell lung cancer KRAS_G12A JAK3 58 50 Female -0.25 -2.14 1.16 537.61 1.00 2109 56 48 2 TRUE 0.12
non-small cell lung cancer KRAS_G12A JAK3 33 33 Male -0.56 -3.05 1.07 770.36 1.00 1543 33 33 0 TRUE 0.21
colorectal cancer KRAS_G12A JAK3 56 63 Sex:overall -0.87 -3.91 1.07 1470.49 1.00 2402 55 62 1 TRUE 0.30
non-small cell lung cancer KRAS_G12A JAK3 91 83 Sex:overall -0.39 -2.52 1.21 725.87 1.00 3652 89 81 2 TRUE 0.16
non-small cell lung cancer KRAS_G12A PAK7 57 71 Female -0.10 -1.42 1.02 989.94 1.00 2014 54 68 3 FALSE 0.06
non-small cell lung cancer KRAS_G12A PAK7 32 62 Male -0.58 -3.31 0.77 1092.06 1.01 1457 32 62 0 FALSE 0.22
non-small cell lung cancer KRAS_G12A PAK7 89 133 Sex:overall -0.30 -2.04 0.99 1579.86 1.00 3471 86 130 3 FALSE 0.15
non-small cell lung cancer KRAS_G12A STAG2 56 75 Female 0.36 -1.08 1.43 1648.32 1.00 2022 54 73 2 TRUE 0.24
non-small cell lung cancer KRAS_G12A STAG2 32 27 Male 1.65 0.31 2.88 1374.19 1.00 1497 28 23 4 TRUE 1.92
non-small cell lung cancer KRAS_G12A STAG2 88 102 Sex:overall 0.96 -1.10 2.74 1441.14 1.00 3519 82 96 6 TRUE 0.52
colorectal cancer KRAS_G12A BRCA2 22 75 Female -0.96 -3.33 0.46 1119.66 1.00 967 22 75 0 TRUE 0.45
colorectal cancer KRAS_G12A BRCA2 31 115 Male -0.55 -1.86 0.64 95.89 1.05 1140 28 112 3 TRUE 0.39
non-small cell lung cancer KRAS_G12A BRCA2 56 72 Female -1.03 -5.47 0.82 1079.94 1.00 2028 56 72 0 TRUE 0.25
non-small cell lung cancer KRAS_G12A BRCA2 32 63 Male 0.59 -0.92 1.90 514.55 1.01 1462 28 59 4 TRUE 0.40
colorectal cancer KRAS_G12A BRCA2 53 190 Sex:overall -0.74 -2.65 0.66 1159.46 1.01 2107 50 187 3 TRUE 0.42
non-small cell lung cancer KRAS_G12A BRCA2 88 135 Sex:overall -0.14 -2.86 1.72 1370.76 1.00 3490 84 131 4 TRUE 0.04
colorectal cancer KRAS_G12A NOTCH3 22 88 Female 0.02 -1.05 1.00 419.48 1.01 958 20 86 2 TRUE 0.01
colorectal cancer KRAS_G12A NOTCH3 29 112 Male 0.04 -0.98 0.92 401.94 1.01 1122 26 109 3 TRUE 0.03
non-small cell lung cancer KRAS_G12A NOTCH3 56 64 Female -0.94 -4.71 0.83 1049.82 1.00 2031 56 64 0 TRUE 0.28
non-small cell lung cancer KRAS_G12A NOTCH3 32 64 Male 0.19 -1.48 1.55 1301.94 1.00 1462 29 61 3 TRUE 0.10
colorectal cancer KRAS_G12A NOTCH3 51 200 Sex:overall 0.02 -1.05 0.99 484.34 1.01 2080 46 195 5 TRUE 0.01
non-small cell lung cancer KRAS_G12A NOTCH3 88 128 Sex:overall -0.40 -3.13 1.25 1199.83 1.00 3493 85 125 3 TRUE 0.14
non-small cell lung cancer KRAS_G12A NOTCH4 56 82 Female -0.35 -1.86 0.76 766.02 1.01 2001 55 81 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A NOTCH4 32 57 Male -0.16 -1.69 1.01 867.23 1.00 1461 30 55 2 TRUE 0.09
non-small cell lung cancer KRAS_G12A NOTCH4 88 139 Sex:overall -0.25 -1.83 0.93 830.22 1.01 3462 85 136 3 TRUE 0.14
colorectal cancer KRAS_G12A FGFR3 25 25 Female -1.02 -4.32 1.05 479.62 1.02 1102 25 25 0 TRUE 0.34
colorectal cancer KRAS_G12A FGFR3 31 35 Male -0.79 -3.57 1.20 438.99 1.01 1303 30 34 1 TRUE 0.29
colorectal cancer KRAS_G12A FGFR3 56 60 Sex:overall -0.88 -3.78 1.15 430.35 1.02 2405 55 59 1 TRUE 0.31
non-small cell lung cancer KRAS_G12A MAP3K13 56 30 Female -0.74 -3.55 1.21 434.03 1.00 2051 55 29 1 FALSE 0.26
non-small cell lung cancer KRAS_G12A MAP3K13 32 22 Male -0.90 -3.81 1.16 636.11 1.00 1491 32 22 0 FALSE 0.30
non-small cell lung cancer KRAS_G12A MAP3K13 88 52 Sex:overall -0.80 -3.63 1.23 660.12 1.00 3542 87 51 1 FALSE 0.28
colorectal cancer KRAS_G12A IGF1R 22 31 Female -0.93 -4.03 0.61 9.30 1.11 1000 22 31 0 TRUE 0.35
colorectal cancer KRAS_G12A IGF1R 29 49 Male -0.76 -3.41 0.73 13.17 1.09 1164 28 48 1 TRUE 0.33
non-small cell lung cancer KRAS_G12A IGF1R 56 31 Female -4.65 -11.00 -0.13 204.24 1.03 2061 56 31 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A IGF1R 32 23 Male -4.69 -11.28 0.16 224.12 1.02 1495 32 23 0 TRUE 0.87
colorectal cancer KRAS_G12A IGF1R 51 80 Sex:overall -0.84 -3.58 0.70 9.76 1.11 2164 50 79 1 TRUE 0.35
non-small cell lung cancer KRAS_G12A IGF1R 88 54 Sex:overall -4.61 -11.06 0.02 182.94 1.03 3556 88 54 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A KEAP1 56 248 Female 0.16 -0.59 0.79 1404.54 1.00 1858 49 241 7 FALSE 0.18
non-small cell lung cancer KRAS_G12A KEAP1 33 290 Male 0.38 -0.31 1.05 1492.12 1.00 1251 24 281 9 FALSE 0.55
non-small cell lung cancer KRAS_G12A KEAP1 89 538 Sex:overall 0.25 -0.90 1.27 1607.92 1.00 3109 73 522 16 FALSE 0.18
colorectal cancer KRAS_G12A KDM5C 22 41 Female -4.48 -12.02 -0.09 686.50 1.00 998 22 41 0 FALSE 0.84
colorectal cancer KRAS_G12A KDM5C 29 28 Male -4.49 -11.76 -0.16 778.42 1.00 1178 29 28 0 FALSE 0.83
non-small cell lung cancer KRAS_G12A KDM5C 56 71 Female -0.50 -2.25 0.87 847.83 1.00 2026 54 69 2 FALSE 0.28
non-small cell lung cancer KRAS_G12A KDM5C 32 35 Male -0.85 -3.50 0.83 1235.47 1.00 1484 32 35 0 FALSE 0.34
colorectal cancer KRAS_G12A KDM5C 51 69 Sex:overall -4.42 -11.49 0.01 681.00 1.00 2176 51 69 0 FALSE 0.84
non-small cell lung cancer KRAS_G12A KDM5C 88 106 Sex:overall -0.66 -2.82 0.91 1128.97 1.00 3510 86 104 2 FALSE 0.30
non-small cell lung cancer KRAS_G12A CDKN2A 59 139 Female 0.17 -0.95 1.09 882.78 1.00 2033 53 133 6 TRUE 0.13
non-small cell lung cancer KRAS_G12A CDKN2A 33 137 Male -1.46 -6.19 0.36 985.00 1.00 1444 33 137 0 TRUE 0.41
non-small cell lung cancer KRAS_G12A CDKN2A 92 276 Sex:overall -0.60 -3.53 1.11 1185.15 1.00 3477 86 270 6 TRUE 0.22
colorectal cancer KRAS_G12A EPHB1 22 32 Female -4.65 -11.54 -0.38 772.39 1.01 997 22 32 0 FALSE 0.93
colorectal cancer KRAS_G12A EPHB1 29 50 Male -4.62 -11.38 -0.32 797.00 1.01 1157 29 50 0 FALSE 0.94
non-small cell lung cancer KRAS_G12A EPHB1 56 81 Female -0.13 -1.78 0.94 1277.55 1.00 2021 55 80 1 FALSE 0.07
non-small cell lung cancer KRAS_G12A EPHB1 33 77 Male 0.44 -0.66 1.56 1258.66 1.00 1448 29 73 4 FALSE 0.35
colorectal cancer KRAS_G12A EPHB1 51 82 Sex:overall -4.58 -11.26 -0.27 780.72 1.01 2154 51 82 0 FALSE 0.93
non-small cell lung cancer KRAS_G12A EPHB1 89 158 Sex:overall 0.17 -1.29 1.43 1541.32 1.00 3469 84 153 5 FALSE 0.09
colorectal cancer KRAS_G12A IRS2 22 29 Female -1.41 -4.61 0.82 1377.04 1.00 1003 22 29 0 FALSE 0.50
colorectal cancer KRAS_G12A IRS2 29 58 Male -1.15 -3.75 0.73 1310.01 1.00 1153 28 57 1 FALSE 0.50
non-small cell lung cancer KRAS_G12A IRS2 56 42 Female -1.38 -4.82 0.60 1258.13 1.00 2051 56 42 0 FALSE 0.45
non-small cell lung cancer KRAS_G12A IRS2 32 42 Male -1.06 -4.11 0.87 1422.58 1.00 1478 31 41 1 FALSE 0.40
colorectal cancer KRAS_G12A IRS2 51 87 Sex:overall -1.26 -3.95 0.85 1297.75 1.00 2156 50 86 1 FALSE 0.49
non-small cell lung cancer KRAS_G12A IRS2 88 84 Sex:overall -1.20 -4.32 0.78 1378.94 1.00 3529 87 83 1 FALSE 0.45
colorectal cancer KRAS_G12A FANCA 22 31 Female -4.47 -11.23 -0.20 104.34 1.01 999 22 31 0 TRUE 0.91
colorectal cancer KRAS_G12A FANCA 29 34 Male -4.49 -11.07 -0.34 101.18 1.01 1175 29 34 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A FANCA 56 39 Female -4.90 -12.10 -0.49 38.80 1.16 2053 56 39 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A FANCA 32 30 Male -4.88 -12.04 -0.47 43.47 1.15 1490 32 30 0 TRUE 0.94
colorectal cancer KRAS_G12A FANCA 51 65 Sex:overall -4.45 -11.08 -0.18 102.44 1.01 2174 51 65 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A FANCA 88 69 Sex:overall -4.82 -12.01 -0.44 40.47 1.16 3543 88 69 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A IL7R 56 51 Female -0.24 -2.02 1.15 1114.45 1.00 2046 54 49 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A IL7R 32 40 Male -0.55 -3.09 1.01 731.56 1.00 1483 32 40 0 FALSE 0.21
non-small cell lung cancer KRAS_G12A IL7R 88 91 Sex:overall -0.38 -2.51 1.05 899.23 1.00 3529 86 89 2 FALSE 0.16
colorectal cancer KRAS_G12A ERBB3 22 52 Female -0.89 -3.41 0.84 818.78 1.00 984 22 52 0 TRUE 0.34
colorectal cancer KRAS_G12A ERBB3 29 70 Male -0.54 -2.34 1.01 934.97 1.00 1143 27 68 2 TRUE 0.28
colorectal cancer KRAS_G12A ERBB3 51 122 Sex:overall -0.70 -2.79 0.99 1054.78 1.00 2127 49 120 2 TRUE 0.33
colorectal cancer KRAS_G12A SMAD4 25 170 Female -0.17 -1.14 0.60 495.78 1.00 976 21 166 4 TRUE 0.16
colorectal cancer KRAS_G12A SMAD4 31 190 Male -0.25 -1.19 0.54 504.57 1.00 1163 28 187 3 TRUE 0.24
non-small cell lung cancer KRAS_G12A SMAD4 58 74 Female -1.14 -4.57 0.58 1176.99 1.00 2085 58 74 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A SMAD4 33 42 Male -0.24 -2.07 1.34 1253.05 1.00 1535 31 40 2 TRUE 0.10
colorectal cancer KRAS_G12A SMAD4 56 360 Sex:overall -0.22 -1.21 0.64 836.41 1.00 2139 49 353 7 TRUE 0.18
non-small cell lung cancer KRAS_G12A SMAD4 91 116 Sex:overall -0.65 -2.80 1.16 1327.01 1.00 3620 89 114 2 TRUE 0.26
colorectal cancer KRAS_G12A ATM 26 100 Female 0.24 -0.79 0.92 21.49 1.16 1046 23 97 3 TRUE 0.21
colorectal cancer KRAS_G12A ATM 32 131 Male 0.21 -0.83 0.88 18.06 1.18 1241 29 128 3 TRUE 0.17
non-small cell lung cancer KRAS_G12A ATM 61 174 Female 1.06 0.45 1.62 1314.74 1.00 2014 48 161 13 TRUE 3.44
non-small cell lung cancer KRAS_G12A ATM 34 114 Male 0.88 0.00 1.51 1361.99 1.00 1474 30 110 4 TRUE 1.79
colorectal cancer KRAS_G12A ATM 58 231 Sex:overall 0.23 -0.80 0.95 23.64 1.14 2287 52 225 6 TRUE 0.18
non-small cell lung cancer KRAS_G12A ATM 95 288 Sex:overall 0.96 0.14 1.63 1313.98 1.00 3488 78 271 17 TRUE 1.95
colorectal cancer KRAS_G12A RB1 25 23 Female -4.78 -11.60 -0.01 248.50 1.02 1107 25 23 0 TRUE 0.94
colorectal cancer KRAS_G12A RB1 31 45 Male -4.86 -11.91 -0.23 251.33 1.02 1298 31 45 0 TRUE 0.96
non-small cell lung cancer KRAS_G12A RB1 58 107 Female -1.32 -3.31 0.14 835.66 1.00 2054 57 106 1 TRUE 0.87
non-small cell lung cancer KRAS_G12A RB1 33 116 Male -1.28 -3.16 0.14 934.06 1.00 1461 32 115 1 TRUE 0.84
colorectal cancer KRAS_G12A RB1 56 68 Sex:overall -4.72 -11.58 -0.20 226.34 1.02 2405 56 68 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A RB1 91 223 Sex:overall -1.28 -3.22 0.28 1039.05 1.00 3515 89 221 2 TRUE 0.81
colorectal cancer KRAS_G12A KMT2D 22 187 Female -1.05 -2.50 0.00 936.36 1.00 920 21 186 1 FALSE 1.00
colorectal cancer KRAS_G12A KMT2D 30 201 Male -0.91 -2.14 0.13 1084.88 1.00 1080 27 198 3 FALSE 0.93
non-small cell lung cancer KRAS_G12A KMT2D 56 136 Female -0.88 -2.58 0.37 1549.33 1.00 1968 55 135 1 FALSE 0.62
non-small cell lung cancer KRAS_G12A KMT2D 33 192 Male -0.05 -1.19 0.91 1310.53 1.00 1365 28 187 5 FALSE 0.03
colorectal cancer KRAS_G12A KMT2D 52 388 Sex:overall -0.98 -2.32 0.11 1042.77 1.00 2000 48 384 4 FALSE 0.88
non-small cell lung cancer KRAS_G12A KMT2D 89 328 Sex:overall -0.47 -2.37 1.10 1432.15 1.00 3333 83 322 6 FALSE 0.24
colorectal cancer KRAS_G12A TSC2 23 62 Female 0.72 -0.58 1.76 859.61 1.01 982 19 58 4 TRUE 0.69
colorectal cancer KRAS_G12A TSC2 29 53 Male -0.15 -3.96 1.15 9.19 1.12 1159 29 53 0 TRUE 0.04
non-small cell lung cancer KRAS_G12A TSC2 57 46 Female 0.76 -0.44 1.70 980.37 1.00 2050 54 43 3 TRUE 0.76
non-small cell lung cancer KRAS_G12A TSC2 32 26 Male 0.66 -0.81 1.76 1059.21 1.00 1494 31 25 1 TRUE 0.51
colorectal cancer KRAS_G12A TSC2 52 115 Sex:overall 0.29 -2.43 1.53 18.60 1.07 2141 48 111 4 TRUE 0.11
non-small cell lung cancer KRAS_G12A TSC2 89 72 Sex:overall 0.69 -0.76 1.81 1192.41 1.00 3544 85 68 4 TRUE 0.51
colorectal cancer KRAS_G12A APC 32 1110 Female 0.12 -0.51 0.76 1274.30 1.00 415 9 1087 23 TRUE 0.16
colorectal cancer KRAS_G12A APC 42 1428 Male 0.22 -0.36 0.85 1296.47 1.00 459 8 1394 34 TRUE 0.32
non-small cell lung cancer KRAS_G12A APC 58 85 Female 0.23 -0.84 1.10 156.33 1.04 2075 55 82 3 TRUE 0.20
non-small cell lung cancer KRAS_G12A APC 33 72 Male 0.22 -0.98 1.12 184.78 1.02 1512 31 70 2 TRUE 0.16
colorectal cancer KRAS_G12A APC 74 2538 Sex:overall 0.18 -0.52 0.90 1407.48 1.00 874 17 2481 57 TRUE 0.20
non-small cell lung cancer KRAS_G12A APC 91 157 Sex:overall 0.23 -1.03 1.18 247.33 1.02 3587 86 152 5 TRUE 0.16
colorectal cancer KRAS_G12A ERBB2 25 38 Female -4.98 -12.47 -0.60 719.58 1.00 1091 25 38 0 TRUE 0.96
colorectal cancer KRAS_G12A ERBB2 31 66 Male -5.02 -12.19 -0.72 766.34 1.00 1273 31 66 0 TRUE 0.98
non-small cell lung cancer KRAS_G12A ERBB2 58 76 Female -5.26 -11.24 -0.67 111.50 1.02 2083 58 76 0 TRUE 1.09
non-small cell lung cancer KRAS_G12A ERBB2 33 53 Male -5.24 -11.15 -0.59 109.96 1.02 1523 33 53 0 TRUE 1.07
colorectal cancer KRAS_G12A ERBB2 56 104 Sex:overall -4.92 -12.18 -0.59 737.94 1.00 2364 56 104 0 TRUE 0.97
non-small cell lung cancer KRAS_G12A ERBB2 91 129 Sex:overall -5.22 -11.15 -0.61 105.78 1.02 3606 91 129 0 TRUE 1.08
colorectal cancer KRAS_G12A JAK1 22 29 Female -0.10 -1.98 1.36 800.98 1.01 1005 21 28 1 TRUE 0.04
colorectal cancer KRAS_G12A JAK1 29 46 Male -0.16 -2.03 1.21 1327.61 1.00 1169 28 45 1 TRUE 0.07
non-small cell lung cancer KRAS_G12A JAK1 56 19 Female 0.33 -1.68 1.92 1578.71 1.00 2075 55 18 1 TRUE 0.14
non-small cell lung cancer KRAS_G12A JAK1 32 33 Male 0.24 -1.73 1.69 1569.09 1.00 1487 31 32 1 TRUE 0.11
colorectal cancer KRAS_G12A JAK1 51 75 Sex:overall -0.14 -2.14 1.33 1099.55 1.00 2174 49 73 2 TRUE 0.06
non-small cell lung cancer KRAS_G12A JAK1 88 52 Sex:overall 0.29 -1.77 2.09 1620.63 1.00 3562 86 50 2 TRUE 0.12
colorectal cancer KRAS_G12A ARID2 22 54 Female 0.06 -1.40 1.28 552.85 1.00 981 20 52 2 FALSE 0.03
colorectal cancer KRAS_G12A ARID2 29 56 Male -0.05 -1.49 1.13 644.94 1.00 1159 28 55 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A ARID2 56 88 Female 0.08 -1.11 1.02 1557.68 1.00 2008 53 85 3 FALSE 0.05
non-small cell lung cancer KRAS_G12A ARID2 32 94 Male 0.03 -1.29 0.98 1335.08 1.00 1439 30 92 2 FALSE 0.02
colorectal cancer KRAS_G12A ARID2 51 110 Sex:overall -0.01 -1.48 1.24 577.98 1.00 2140 48 107 3 FALSE 0.00
non-small cell lung cancer KRAS_G12A ARID2 88 182 Sex:overall 0.04 -1.45 1.23 1577.10 1.00 3447 83 177 5 FALSE 0.02
non-small cell lung cancer KRAS_G12A SOX17 56 34 Female -0.81 -3.35 1.05 388.03 1.01 2048 55 33 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A SOX17 32 27 Male -1.00 -3.94 0.94 417.20 1.00 1486 32 27 0 FALSE 0.33
non-small cell lung cancer KRAS_G12A SOX17 88 61 Sex:overall -0.89 -3.51 1.04 410.11 1.01 3534 87 60 1 FALSE 0.31
colorectal cancer KRAS_G12A MTOR 22 75 Female -1.81 -5.09 0.13 809.04 1.00 966 22 75 0 TRUE 0.74
colorectal cancer KRAS_G12A MTOR 29 65 Male -1.55 -4.57 0.34 1231.29 1.00 1149 28 64 1 TRUE 0.70
non-small cell lung cancer KRAS_G12A MTOR 56 64 Female -0.64 -2.45 0.70 819.95 1.00 2029 55 63 1 TRUE 0.37
non-small cell lung cancer KRAS_G12A MTOR 32 51 Male -0.60 -2.42 0.86 877.73 1.00 1470 31 50 1 TRUE 0.33
colorectal cancer KRAS_G12A MTOR 51 140 Sex:overall -1.64 -4.59 0.46 950.64 1.00 2115 50 139 1 TRUE 0.72
non-small cell lung cancer KRAS_G12A MTOR 88 115 Sex:overall -0.62 -2.43 0.81 829.89 1.00 3499 86 113 2 TRUE 0.34
non-small cell lung cancer KRAS_G12A RFWD2 56 30 Female 0.13 -1.81 1.49 861.25 1.00 2050 55 29 1 FALSE 0.06
non-small cell lung cancer KRAS_G12A RFWD2 32 27 Male 0.18 -1.74 1.62 752.85 1.00 1487 31 26 1 FALSE 0.08
non-small cell lung cancer KRAS_G12A RFWD2 88 57 Sex:overall 0.17 -1.83 1.65 785.07 1.00 3537 86 55 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A IRS1 56 38 Female -1.08 -4.44 0.68 994.72 1.01 2043 56 38 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A IRS1 32 35 Male -0.79 -3.42 0.98 1196.11 1.00 1480 31 34 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A IRS1 88 73 Sex:overall -0.91 -3.77 0.82 1161.18 1.00 3523 87 72 1 FALSE 0.36
colorectal cancer KRAS_G12A NOTCH1 26 85 Female -0.36 -1.72 0.71 593.20 1.00 1065 24 83 2 TRUE 0.26
colorectal cancer KRAS_G12A NOTCH1 31 87 Male -0.44 -1.93 0.60 531.11 1.01 1266 30 86 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A NOTCH1 58 64 Female 0.76 -0.48 1.80 767.97 1.00 2099 53 59 5 TRUE 0.76
non-small cell lung cancer KRAS_G12A NOTCH1 33 66 Male -0.76 -4.76 1.04 1117.30 1.00 1515 33 66 0 TRUE 0.19
colorectal cancer KRAS_G12A NOTCH1 57 172 Sex:overall -0.41 -1.77 0.70 639.66 1.00 2331 54 169 3 TRUE 0.29
non-small cell lung cancer KRAS_G12A NOTCH1 91 130 Sex:overall 0.04 -2.84 2.05 1461.56 1.00 3614 86 125 5 TRUE 0.01
colorectal cancer KRAS_G12A NTRK1 22 24 Female 1.09 -0.30 2.18 1038.26 1.00 1007 21 23 1 TRUE 1.04
colorectal cancer KRAS_G12A NTRK1 29 40 Male 1.35 0.27 2.33 837.78 1.00 1170 25 36 4 TRUE 1.83
non-small cell lung cancer KRAS_G12A NTRK1 56 38 Female 0.74 -0.59 1.87 1427.52 1.00 2057 53 35 3 TRUE 0.65
non-small cell lung cancer KRAS_G12A NTRK1 32 50 Male 0.34 -1.27 1.50 1506.04 1.00 1470 31 49 1 TRUE 0.20
colorectal cancer KRAS_G12A NTRK1 51 64 Sex:overall 1.22 -0.20 2.40 1059.91 1.00 2177 46 59 5 TRUE 1.18
non-small cell lung cancer KRAS_G12A NTRK1 88 88 Sex:overall 0.55 -1.10 2.02 1662.99 1.00 3527 84 84 4 TRUE 0.30
non-small cell lung cancer KRAS_G12A INPP4A 56 21 Female -0.55 -3.47 1.44 1361.57 1.00 2059 55 20 1 FALSE 0.18
non-small cell lung cancer KRAS_G12A INPP4A 32 32 Male -1.19 -5.02 1.09 1360.83 1.00 1482 32 32 0 FALSE 0.35
non-small cell lung cancer KRAS_G12A INPP4A 88 53 Sex:overall -0.80 -4.03 1.49 1382.93 1.00 3541 87 52 1 FALSE 0.25
colorectal cancer KRAS_G12A SETD2 22 34 Female -1.03 -4.21 0.86 1248.53 1.00 999 22 34 0 FALSE 0.35
colorectal cancer KRAS_G12A SETD2 29 79 Male -0.42 -2.45 0.96 933.13 1.00 1144 27 77 2 FALSE 0.21
non-small cell lung cancer KRAS_G12A SETD2 57 131 Female -0.01 -1.20 0.91 215.07 1.03 1987 52 126 5 FALSE 0.01
non-small cell lung cancer KRAS_G12A SETD2 32 94 Male -0.20 -1.58 0.80 370.85 1.01 1436 31 93 1 FALSE 0.14
colorectal cancer KRAS_G12A SETD2 51 113 Sex:overall -0.70 -3.19 1.16 1002.47 1.00 2143 49 111 2 FALSE 0.27
non-small cell lung cancer KRAS_G12A SETD2 89 225 Sex:overall -0.12 -1.56 0.90 355.74 1.01 3423 83 219 6 FALSE 0.07
colorectal cancer KRAS_G12A PBRM1 22 38 Female -1.28 -4.28 0.70 931.14 1.00 994 22 38 0 TRUE 0.48
colorectal cancer KRAS_G12A PBRM1 29 56 Male -1.10 -3.95 0.66 791.23 1.00 1159 28 55 1 TRUE 0.46
non-small cell lung cancer KRAS_G12A PBRM1 56 57 Female -0.07 -1.48 1.10 1185.02 1.00 2044 54 55 2 TRUE 0.04
non-small cell lung cancer KRAS_G12A PBRM1 32 57 Male -0.17 -1.68 1.07 1364.54 1.00 1469 31 56 1 TRUE 0.09
colorectal cancer KRAS_G12A PBRM1 51 94 Sex:overall -1.17 -4.02 0.73 1008.82 1.00 2153 50 93 1 TRUE 0.45
non-small cell lung cancer KRAS_G12A PBRM1 88 114 Sex:overall -0.13 -1.69 1.21 966.94 1.00 3513 85 111 3 TRUE 0.06
colorectal cancer KRAS_G12A EPHA3 22 52 Female -0.04 -1.46 1.18 1232.42 1.00 982 21 51 1 FALSE 0.02
colorectal cancer KRAS_G12A EPHA3 29 61 Male 0.02 -1.34 1.16 1125.80 1.00 1152 27 59 2 FALSE 0.01
non-small cell lung cancer KRAS_G12A EPHA3 56 146 Female 0.21 -0.63 0.98 522.67 1.00 1961 52 142 4 FALSE 0.21
non-small cell lung cancer KRAS_G12A EPHA3 33 96 Male 0.34 -0.46 1.17 243.91 1.03 1434 29 92 4 FALSE 0.36
colorectal cancer KRAS_G12A EPHA3 51 113 Sex:overall 0.00 -1.45 1.23 1169.24 1.00 2134 48 110 3 FALSE 0.00
non-small cell lung cancer KRAS_G12A EPHA3 89 242 Sex:overall 0.27 -0.68 1.12 446.09 1.01 3395 81 234 8 FALSE 0.25
colorectal cancer KRAS_G12A KIT 25 23 Female -4.22 -11.19 -0.02 180.32 1.01 1105 25 23 0 TRUE 0.77
colorectal cancer KRAS_G12A KIT 31 31 Male -4.22 -10.95 0.04 173.69 1.01 1305 31 31 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A KIT 58 38 Female -4.93 -12.79 -0.40 442.70 1.00 2117 58 38 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A KIT 33 43 Male -4.90 -12.62 -0.27 444.70 1.00 1535 33 43 0 TRUE 0.91
colorectal cancer KRAS_G12A KIT 56 54 Sex:overall -4.18 -10.95 0.00 177.30 1.01 2410 56 54 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A KIT 91 81 Sex:overall -4.84 -12.76 -0.24 470.85 1.00 3652 91 81 0 TRUE 0.88
colorectal cancer KRAS_G12A KDR 25 26 Female -0.81 -3.84 1.28 1184.93 1.00 1105 24 25 1 TRUE 0.27
colorectal cancer KRAS_G12A KDR 31 49 Male -1.32 -4.79 0.78 1281.95 1.00 1292 31 49 0 TRUE 0.44
non-small cell lung cancer KRAS_G12A KDR 58 94 Female 0.60 -0.38 1.44 1120.75 1.00 2074 52 88 6 TRUE 0.72
non-small cell lung cancer KRAS_G12A KDR 33 60 Male -0.27 -3.89 1.11 667.18 1.01 1516 33 60 0 TRUE 0.08
colorectal cancer KRAS_G12A KDR 56 75 Sex:overall -1.07 -4.11 1.15 1444.77 1.00 2397 55 74 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A KDR 91 154 Sex:overall 0.20 -2.12 1.34 1123.12 1.00 3590 85 148 6 TRUE 0.09
colorectal cancer KRAS_G12A RICTOR 22 26 Female -1.17 -4.08 0.91 742.42 1.00 1005 22 26 0 FALSE 0.44
colorectal cancer KRAS_G12A RICTOR 29 44 Male -0.98 -3.44 0.99 665.39 1.01 1170 28 43 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A RICTOR 56 39 Female -0.78 -3.29 1.17 183.55 1.02 2054 55 38 1 FALSE 0.31
non-small cell lung cancer KRAS_G12A RICTOR 32 25 Male -0.96 -3.98 1.17 261.36 1.01 1495 32 25 0 FALSE 0.33
colorectal cancer KRAS_G12A RICTOR 51 70 Sex:overall -1.07 -3.90 0.91 737.38 1.00 2175 50 69 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A RICTOR 88 64 Sex:overall -0.86 -3.57 1.25 209.66 1.02 3549 87 63 1 FALSE 0.32
colorectal cancer KRAS_G12A RAD50 22 21 Female -0.58 -3.36 1.35 1485.89 1.00 1011 21 20 1 FALSE 0.20
colorectal cancer KRAS_G12A RAD50 29 39 Male -1.04 -4.49 0.93 1079.11 1.00 1170 29 39 0 FALSE 0.33
colorectal cancer KRAS_G12A RAD50 51 60 Sex:overall -0.79 -3.67 1.21 1415.32 1.00 2181 50 59 1 FALSE 0.27
colorectal cancer KRAS_G12A CSF1R 26 21 Female 0.51 -1.33 2.19 1137.91 1.00 1108 24 19 2 TRUE 0.25
colorectal cancer KRAS_G12A CSF1R 31 35 Male -0.30 -3.39 1.49 1347.65 1.00 1304 31 35 0 TRUE 0.08
non-small cell lung cancer KRAS_G12A CSF1R 58 36 Female 0.46 -1.11 1.60 715.42 1.00 2124 56 34 2 TRUE 0.30
non-small cell lung cancer KRAS_G12A CSF1R 33 33 Male 0.38 -1.26 1.58 776.64 1.00 1543 32 32 1 TRUE 0.21
colorectal cancer KRAS_G12A CSF1R 57 56 Sex:overall 0.08 -2.53 1.86 1193.52 1.00 2412 55 54 2 TRUE 0.03
non-small cell lung cancer KRAS_G12A CSF1R 91 69 Sex:overall 0.39 -1.30 1.68 970.92 1.00 3667 88 66 3 TRUE 0.22
non-small cell lung cancer KRAS_G12A PARK2 56 39 Female -0.99 -3.95 0.93 1229.05 1.00 2053 55 38 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A PARK2 32 26 Male -1.19 -4.54 0.90 1115.67 1.00 1492 32 26 0 FALSE 0.37
non-small cell lung cancer KRAS_G12A PARK2 88 65 Sex:overall -1.07 -4.11 1.00 1253.30 1.00 3545 87 64 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A NTRK2 56 36 Female 0.56 -0.99 1.68 293.88 1.01 2060 54 34 2 FALSE 0.37
non-small cell lung cancer KRAS_G12A NTRK2 32 31 Male 0.50 -1.16 1.65 345.63 1.01 1490 31 30 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A NTRK2 88 67 Sex:overall 0.53 -1.15 1.76 394.75 1.00 3550 85 64 3 FALSE 0.32
colorectal cancer KRAS_G12A PTCH1 22 67 Female -1.68 -4.30 0.40 253.85 1.01 974 21 66 1 TRUE 0.72
colorectal cancer KRAS_G12A PTCH1 29 78 Male -1.87 -4.76 0.22 405.67 1.00 1148 29 78 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A PTCH1 56 39 Female -4.50 -11.49 -0.32 460.91 1.00 2053 56 39 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A PTCH1 32 23 Male -4.45 -11.55 -0.18 505.83 1.00 1495 32 23 0 TRUE 0.87
colorectal cancer KRAS_G12A PTCH1 51 145 Sex:overall -1.74 -4.42 0.36 332.11 1.01 2122 50 144 1 TRUE 0.72
non-small cell lung cancer KRAS_G12A PTCH1 88 62 Sex:overall -4.43 -11.37 -0.30 477.30 1.00 3548 88 62 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A TET1 56 63 Female 0.12 -1.45 1.23 1287.71 1.00 2021 55 62 1 FALSE 0.06
non-small cell lung cancer KRAS_G12A TET1 33 63 Male 0.65 -0.57 1.77 989.84 1.00 1461 29 59 4 FALSE 0.59
non-small cell lung cancer KRAS_G12A TET1 89 126 Sex:overall 0.39 -1.22 1.62 1370.11 1.00 3482 84 121 5 FALSE 0.24
colorectal cancer KRAS_G12A FGFR2 25 21 Female -0.54 -3.49 1.46 1048.71 1.00 1109 24 20 1 TRUE 0.18
colorectal cancer KRAS_G12A FGFR2 31 32 Male -0.85 -4.13 1.23 1023.37 1.00 1303 31 32 0 TRUE 0.28
colorectal cancer KRAS_G12A FGFR2 56 53 Sex:overall -0.69 -3.61 1.38 997.07 1.00 2412 55 52 1 TRUE 0.23
colorectal cancer KRAS_G12A TBX3 22 37 Female -1.23 -4.45 0.90 721.22 1.00 997 22 37 0 FALSE 0.44
colorectal cancer KRAS_G12A TBX3 29 43 Male -1.03 -3.95 0.89 679.70 1.00 1170 28 42 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A TBX3 56 76 Female -0.89 -4.36 0.73 1015.05 1.00 2018 56 76 0 FALSE 0.29
non-small cell lung cancer KRAS_G12A TBX3 32 61 Male 0.13 -1.25 1.50 952.43 1.00 1466 29 58 3 FALSE 0.07
colorectal cancer KRAS_G12A TBX3 51 80 Sex:overall -1.15 -4.22 0.92 707.63 1.00 2167 50 79 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A TBX3 88 137 Sex:overall -0.37 -2.79 1.22 1521.54 1.00 3484 85 134 3 FALSE 0.15
colorectal cancer KRAS_G12A HNF1A 25 27 Female -4.54 -11.30 0.06 1194.66 1.00 1100 25 27 0 TRUE 0.92
colorectal cancer KRAS_G12A HNF1A 31 25 Male -4.51 -11.31 0.01 1091.92 1.00 1309 31 25 0 TRUE 0.92
colorectal cancer KRAS_G12A HNF1A 56 52 Sex:overall -4.46 -11.09 0.12 1148.55 1.00 2409 56 52 0 TRUE 0.91
colorectal cancer KRAS_G12A DICER1 22 29 Female -4.59 -11.59 -0.15 515.23 1.00 1001 22 29 0 TRUE 0.90
colorectal cancer KRAS_G12A DICER1 29 47 Male -4.61 -11.47 -0.37 516.90 1.00 1170 29 47 0 TRUE 0.94
non-small cell lung cancer KRAS_G12A DICER1 56 52 Female -4.71 -11.65 -0.51 217.22 1.02 2044 56 52 0 TRUE 0.94
non-small cell lung cancer KRAS_G12A DICER1 32 38 Male -4.69 -11.35 -0.55 215.84 1.02 1481 32 38 0 TRUE 0.94
colorectal cancer KRAS_G12A DICER1 51 76 Sex:overall -4.54 -11.42 -0.29 503.77 1.00 2171 51 76 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A DICER1 88 90 Sex:overall -4.65 -11.38 -0.48 203.50 1.02 3525 88 90 0 TRUE 0.95
colorectal cancer KRAS_G12A SMAD3 25 46 Female 1.24 -0.09 2.41 965.95 1.00 991 20 41 5 TRUE 1.29
colorectal cancer KRAS_G12A SMAD3 29 61 Male -0.82 -6.00 1.35 757.94 1.00 1151 29 61 0 TRUE 0.17
colorectal cancer KRAS_G12A SMAD3 54 107 Sex:overall 0.22 -3.33 2.16 1149.30 1.00 2142 49 102 5 TRUE 0.06
colorectal cancer KRAS_G12A NTRK3 22 24 Female -1.28 -4.50 0.91 640.54 1.00 1007 22 24 0 FALSE 0.41
colorectal cancer KRAS_G12A NTRK3 29 46 Male -1.03 -4.04 0.96 478.05 1.00 1165 28 45 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A NTRK3 56 106 Female 0.20 -0.67 0.99 1368.71 1.00 2000 53 103 3 FALSE 0.20
non-small cell lung cancer KRAS_G12A NTRK3 34 101 Male 0.35 -0.57 1.28 1471.51 1.00 1433 30 97 4 FALSE 0.35
colorectal cancer KRAS_G12A NTRK3 51 70 Sex:overall -1.15 -4.33 0.97 617.61 1.00 2172 50 69 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A NTRK3 90 207 Sex:overall 0.28 -0.79 1.25 1497.85 1.00 3433 83 200 7 FALSE 0.22
colorectal cancer KRAS_G12A AXIN1 22 33 Female -4.50 -11.30 -0.22 1195.10 1.00 999 22 33 0 FALSE 0.92
colorectal cancer KRAS_G12A AXIN1 29 38 Male -4.49 -11.36 -0.20 1249.86 1.00 1172 29 38 0 FALSE 0.92
colorectal cancer KRAS_G12A AXIN1 51 71 Sex:overall -4.46 -11.45 -0.14 1286.35 1.00 2171 51 71 0 FALSE 0.91
colorectal cancer KRAS_G12A GRIN2A 23 62 Female -0.56 -2.42 0.88 721.82 1.00 971 21 60 2 FALSE 0.29
colorectal cancer KRAS_G12A GRIN2A 29 74 Male -1.02 -3.73 0.52 775.45 1.01 1141 29 74 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A GRIN2A 56 102 Female -2.27 -5.09 -0.23 430.38 1.00 1996 56 102 0 FALSE 1.13
non-small cell lung cancer KRAS_G12A GRIN2A 32 91 Male -2.04 -4.65 -0.06 394.88 1.00 1433 31 90 1 FALSE 1.02
colorectal cancer KRAS_G12A GRIN2A 52 136 Sex:overall -0.77 -3.04 0.72 849.39 1.01 2112 50 134 2 FALSE 0.37
non-small cell lung cancer KRAS_G12A GRIN2A 88 193 Sex:overall -2.15 -4.78 -0.08 443.55 1.00 3429 87 192 1 FALSE 1.07
colorectal cancer KRAS_G12A PALB2 22 20 Female -1.00 -4.45 1.10 1223.56 1.00 1010 22 20 0 TRUE 0.31
colorectal cancer KRAS_G12A PALB2 29 36 Male -0.73 -3.65 1.21 1095.24 1.00 1172 28 35 1 TRUE 0.25
non-small cell lung cancer KRAS_G12A PALB2 56 31 Female -1.08 -4.21 0.93 1169.14 1.00 2062 56 31 0 TRUE 0.35
non-small cell lung cancer KRAS_G12A PALB2 32 29 Male -0.75 -3.40 1.17 1237.23 1.00 1491 31 28 1 TRUE 0.27
colorectal cancer KRAS_G12A PALB2 51 56 Sex:overall -0.86 -3.94 1.28 1050.19 1.00 2182 50 55 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A PALB2 88 60 Sex:overall -0.90 -3.87 1.25 1240.30 1.00 3553 87 59 1 TRUE 0.31
colorectal cancer KRAS_G12A CTCF 22 40 Female -4.63 -11.56 -0.14 836.61 1.00 995 22 40 0 FALSE 0.93
colorectal cancer KRAS_G12A CTCF 29 50 Male -4.60 -11.54 -0.22 816.47 1.00 1161 29 50 0 FALSE 0.93
colorectal cancer KRAS_G12A CTCF 51 90 Sex:overall -4.59 -11.27 -0.23 835.20 1.00 2156 51 90 0 FALSE 0.93
colorectal cancer KRAS_G12A CDH1 25 21 Female -0.48 -3.50 1.45 654.97 1.00 1113 24 20 1 TRUE 0.15
colorectal cancer KRAS_G12A CDH1 31 33 Male -0.86 -4.36 1.06 636.56 1.00 1302 31 33 0 TRUE 0.25
colorectal cancer KRAS_G12A CDH1 56 54 Sex:overall -0.67 -4.01 1.39 970.07 1.00 2415 55 53 1 TRUE 0.21
colorectal cancer KRAS_G12A CDK12 22 42 Female -0.52 -3.18 1.04 1017.16 1.00 993 22 42 0 FALSE 0.19
colorectal cancer KRAS_G12A CDK12 30 48 Male -0.16 -2.08 1.23 1131.61 1.00 1165 28 46 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A CDK12 56 31 Female -1.10 -4.51 0.96 1030.20 1.00 2061 56 31 0 FALSE 0.36
non-small cell lung cancer KRAS_G12A CDK12 32 28 Male -0.77 -3.49 1.24 1035.05 1.00 1492 31 27 1 FALSE 0.28
colorectal cancer KRAS_G12A CDK12 52 90 Sex:overall -0.34 -2.55 1.24 1073.55 1.00 2158 50 88 2 FALSE 0.14
non-small cell lung cancer KRAS_G12A CDK12 88 59 Sex:overall -0.92 -3.74 1.13 1007.96 1.00 3553 87 58 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A STK11 59 295 Female 0.60 -0.03 1.08 91.40 1.04 1882 48 284 11 TRUE 1.33
non-small cell lung cancer KRAS_G12A STK11 33 248 Male 0.78 0.16 1.42 273.72 1.02 1345 22 237 11 TRUE 1.80
non-small cell lung cancer KRAS_G12A STK11 92 543 Sex:overall 0.68 -0.12 1.40 318.83 1.02 3227 70 521 22 TRUE 1.05
colorectal cancer KRAS_G12A BRD4 22 31 Female -1.48 -5.01 0.69 1045.18 1.00 998 22 31 0 FALSE 0.53
colorectal cancer KRAS_G12A BRD4 29 57 Male -1.23 -4.13 0.76 956.56 1.00 1155 28 56 1 FALSE 0.49
non-small cell lung cancer KRAS_G12A BRD4 56 27 Female -4.40 -11.22 -0.04 827.11 1.00 2066 56 27 0 FALSE 0.87
non-small cell lung cancer KRAS_G12A BRD4 32 26 Male -4.47 -11.58 0.02 909.23 1.00 1492 32 26 0 FALSE 0.87
colorectal cancer KRAS_G12A BRD4 51 88 Sex:overall -1.35 -4.29 0.79 1063.62 1.00 2153 50 87 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A BRD4 88 53 Sex:overall -4.40 -11.12 0.06 835.61 1.00 3558 88 53 0 FALSE 0.88
colorectal cancer KRAS_G12A ASXL1 22 49 Female -1.12 -3.96 0.55 105.25 1.05 987 21 48 1 TRUE 0.51
colorectal cancer KRAS_G12A ASXL1 29 60 Male -1.28 -4.66 0.34 58.74 1.07 1148 29 60 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A ASXL1 56 40 Female -1.11 -4.20 0.88 1220.64 1.00 2053 55 39 1 TRUE 0.41
non-small cell lung cancer KRAS_G12A ASXL1 32 46 Male -1.50 -4.97 0.59 1325.11 1.00 1485 32 46 0 TRUE 0.52
colorectal cancer KRAS_G12A ASXL1 51 109 Sex:overall -1.16 -4.15 0.51 95.00 1.06 2135 50 108 1 TRUE 0.51
non-small cell lung cancer KRAS_G12A ASXL1 88 86 Sex:overall -1.26 -4.55 0.94 1353.02 1.00 3538 87 85 1 TRUE 0.45
colorectal cancer KRAS_G12A EP300 22 53 Female 0.24 -1.09 1.25 578.51 1.02 989 21 52 1 TRUE 0.16
colorectal cancer KRAS_G12A EP300 29 72 Male 0.34 -0.84 1.29 801.33 1.01 1147 26 69 3 TRUE 0.28
non-small cell lung cancer KRAS_G12A EP300 56 54 Female 0.76 -0.41 1.75 1520.18 1.00 2048 52 50 4 TRUE 0.77
non-small cell lung cancer KRAS_G12A EP300 32 54 Male 0.40 -1.16 1.45 1275.26 1.00 1469 31 53 1 TRUE 0.26
colorectal cancer KRAS_G12A EP300 51 125 Sex:overall 0.29 -1.01 1.31 776.49 1.01 2136 47 121 4 TRUE 0.21
non-small cell lung cancer KRAS_G12A EP300 88 108 Sex:overall 0.57 -0.92 1.67 1452.19 1.00 3517 83 103 5 TRUE 0.40
colorectal cancer KRAS_G12A ERBB4 26 60 Female 0.24 -1.05 1.37 523.96 1.01 1075 23 57 3 TRUE 0.16
colorectal cancer KRAS_G12A ERBB4 31 78 Male -0.01 -1.49 1.10 835.74 1.00 1269 30 77 1 TRUE 0.00
non-small cell lung cancer KRAS_G12A ERBB4 58 108 Female -0.27 -2.23 0.91 1237.74 1.00 2062 57 107 1 TRUE 0.13
non-small cell lung cancer KRAS_G12A ERBB4 35 85 Male 0.85 -0.18 1.92 755.49 1.00 1509 29 79 6 TRUE 0.94
colorectal cancer KRAS_G12A ERBB4 57 138 Sex:overall 0.10 -1.45 1.28 934.55 1.00 2344 53 134 4 TRUE 0.05
non-small cell lung cancer KRAS_G12A ERBB4 93 193 Sex:overall 0.26 -1.77 1.87 1378.73 1.00 3571 86 186 7 TRUE 0.11
non-small cell lung cancer KRAS_G12A MDC1 56 52 Female -1.42 -4.70 0.43 1021.54 1.00 2033 56 52 0 FALSE 0.50
non-small cell lung cancer KRAS_G12A MDC1 32 43 Male -1.16 -3.83 0.77 625.25 1.00 1476 31 42 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A MDC1 88 95 Sex:overall -1.27 -4.05 0.62 816.97 1.00 3509 87 94 1 FALSE 0.51
non-small cell lung cancer KRAS_G12A RECQL4 56 36 Female -4.64 -11.80 -0.33 507.11 1.00 2046 56 36 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A RECQL4 32 28 Male -4.58 -11.60 -0.12 509.07 1.00 1485 32 28 0 TRUE 0.84
non-small cell lung cancer KRAS_G12A RECQL4 88 64 Sex:overall -4.58 -11.43 -0.30 495.82 1.01 3531 88 64 0 TRUE 0.86
colorectal cancer KRAS_G12A MED12 22 54 Female -4.66 -11.31 -0.69 306.49 1.01 982 22 54 0 TRUE 1.03
colorectal cancer KRAS_G12A MED12 29 54 Male -4.64 -11.35 -0.68 291.01 1.01 1158 29 54 0 TRUE 1.02
non-small cell lung cancer KRAS_G12A MED12 56 137 Female 0.26 -0.74 1.09 1513.44 1.00 1971 51 132 5 TRUE 0.23
non-small cell lung cancer KRAS_G12A MED12 32 39 Male 0.09 -1.64 1.50 1444.34 1.00 1482 31 38 1 TRUE 0.04
colorectal cancer KRAS_G12A MED12 51 108 Sex:overall -4.61 -11.26 -0.63 310.34 1.01 2140 51 108 0 TRUE 1.04
non-small cell lung cancer KRAS_G12A MED12 88 176 Sex:overall 0.15 -1.54 1.76 1460.25 1.00 3453 82 170 6 TRUE 0.07
non-small cell lung cancer KRAS_G12A ERCC5 56 39 Female -1.28 -4.80 0.66 1089.62 1.00 2041 56 39 0 TRUE 0.44
non-small cell lung cancer KRAS_G12A ERCC5 32 34 Male -0.96 -3.75 0.98 1135.19 1.00 1485 31 33 1 TRUE 0.37
non-small cell lung cancer KRAS_G12A ERCC5 88 73 Sex:overall -1.10 -4.37 0.87 1119.51 1.00 3526 87 72 1 TRUE 0.41
colorectal cancer KRAS_G12A BRCA1 22 28 Female -2.02 -5.84 0.56 5.86 1.74 1003 22 28 0 TRUE 0.50
colorectal cancer KRAS_G12A BRCA1 29 51 Male -1.84 -5.95 0.67 5.82 1.96 1166 28 50 1 TRUE 0.45
non-small cell lung cancer KRAS_G12A BRCA1 56 50 Female 0.29 -1.22 1.38 939.93 1.00 2045 55 49 1 TRUE 0.18
non-small cell lung cancer KRAS_G12A BRCA1 33 47 Male 0.62 -0.70 1.75 1267.36 1.00 1475 30 44 3 TRUE 0.50
colorectal cancer KRAS_G12A BRCA1 51 79 Sex:overall -1.94 -5.87 0.73 5.41 1.88 2169 50 78 1 TRUE 0.48
non-small cell lung cancer KRAS_G12A BRCA1 89 97 Sex:overall 0.47 -0.99 1.80 1448.21 1.00 3520 85 93 4 TRUE 0.30
colorectal cancer KRAS_G12A RBM10 22 41 Female -4.76 -11.98 -0.29 941.17 1.01 994 22 41 0 FALSE 0.92
colorectal cancer KRAS_G12A RBM10 29 31 Male -4.78 -12.15 -0.19 937.60 1.01 1173 29 31 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A RBM10 56 239 Female 0.86 0.23 1.43 1368.25 1.00 1880 45 228 11 FALSE 2.31
non-small cell lung cancer KRAS_G12A RBM10 32 144 Male 1.05 0.38 1.74 1244.96 1.00 1386 23 135 9 FALSE 2.71
colorectal cancer KRAS_G12A RBM10 51 72 Sex:overall -4.70 -11.78 -0.21 931.45 1.01 2167 51 72 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A RBM10 88 383 Sex:overall 0.94 0.13 1.72 1439.65 1.00 3266 68 363 20 FALSE 1.55
colorectal cancer KRAS_G12A TSC1 22 27 Female -4.72 -11.94 -0.19 159.58 1.02 1004 22 27 0 TRUE 0.91
colorectal cancer KRAS_G12A TSC1 29 40 Male -4.77 -11.93 -0.31 165.85 1.02 1173 29 40 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A TSC1 56 30 Female 0.99 -0.40 2.08 974.35 1.00 2064 54 28 2 TRUE 0.97
non-small cell lung cancer KRAS_G12A TSC1 32 27 Male 1.06 -0.33 2.17 1235.23 1.00 1493 30 25 2 TRUE 1.04
colorectal cancer KRAS_G12A TSC1 51 67 Sex:overall -4.72 -11.93 -0.08 156.68 1.02 2177 51 67 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A TSC1 88 57 Sex:overall 1.02 -0.41 2.24 1269.43 1.00 3557 84 53 4 TRUE 0.89
colorectal cancer KRAS_G12A FLCN 22 30 Female -0.01 -4.10 1.81 1235.76 1.00 1000 22 30 0 TRUE 0.00
colorectal cancer KRAS_G12A FLCN 29 24 Male 1.07 -0.47 2.50 113.72 1.03 1187 26 21 3 TRUE 0.73
colorectal cancer KRAS_G12A FLCN 51 54 Sex:overall 0.53 -1.97 2.38 492.90 1.01 2187 48 51 3 TRUE 0.19
colorectal cancer KRAS_G12A NF1 22 55 Female -0.64 -3.36 0.78 953.06 1.00 984 22 55 0 TRUE 0.24
colorectal cancer KRAS_G12A NF1 30 87 Male -0.10 -1.59 1.02 1221.40 1.00 1144 27 84 3 TRUE 0.06
non-small cell lung cancer KRAS_G12A NF1 56 165 Female -1.26 -2.92 -0.11 1063.59 1.00 1951 55 164 1 TRUE 1.13
non-small cell lung cancer KRAS_G12A NF1 32 150 Male -1.07 -2.71 0.16 850.34 1.00 1391 30 148 2 TRUE 0.90
colorectal cancer KRAS_G12A NF1 52 142 Sex:overall -0.36 -2.39 1.02 1013.88 1.00 2128 49 139 3 TRUE 0.16
non-small cell lung cancer KRAS_G12A NF1 88 315 Sex:overall -1.15 -2.75 0.16 1047.08 1.00 3342 85 312 3 TRUE 0.93
colorectal cancer KRAS_G12A FLT1 22 30 Female -4.69 -10.87 -0.46 323.13 1.01 1003 22 30 0 FALSE 1.03
colorectal cancer KRAS_G12A FLT1 29 52 Male -4.71 -11.18 -0.43 307.20 1.01 1162 29 52 0 FALSE 1.03
non-small cell lung cancer KRAS_G12A FLT1 57 75 Female 0.56 -0.50 1.53 783.19 1.00 2027 52 70 5 FALSE 0.53
non-small cell lung cancer KRAS_G12A FLT1 32 61 Male -0.43 -4.11 1.08 837.09 1.00 1462 32 61 0 FALSE 0.12
colorectal cancer KRAS_G12A FLT1 51 82 Sex:overall -4.62 -10.71 -0.40 309.41 1.01 2165 51 82 0 FALSE 1.03
non-small cell lung cancer KRAS_G12A FLT1 89 136 Sex:overall 0.09 -2.04 1.43 987.30 1.00 3489 84 131 5 FALSE 0.03
colorectal cancer KRAS_G12A RPTOR 22 32 Female -0.86 -3.84 1.13 481.98 1.01 998 21 31 1 FALSE 0.31
colorectal cancer KRAS_G12A RPTOR 29 38 Male -1.11 -4.41 0.92 367.48 1.01 1172 29 38 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A RPTOR 56 34 Female -0.97 -3.84 1.00 570.80 1.01 2059 55 33 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A RPTOR 32 31 Male -1.22 -4.42 0.93 928.28 1.00 1488 32 31 0 FALSE 0.42
colorectal cancer KRAS_G12A RPTOR 51 70 Sex:overall -0.99 -3.98 1.03 408.18 1.01 2170 50 69 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A RPTOR 88 65 Sex:overall -1.09 -4.12 1.16 832.69 1.00 3547 87 64 1 FALSE 0.38
colorectal cancer KRAS_G12A RASA1 22 30 Female 0.02 -2.82 1.59 1094.83 1.00 1002 22 30 0 FALSE 0.00
colorectal cancer KRAS_G12A RASA1 31 43 Male 0.52 -0.97 1.78 1231.81 1.00 1175 28 40 3 FALSE 0.34
non-small cell lung cancer KRAS_G12A RASA1 56 47 Female -6.99 -11.70 -0.91 2.44 1.58 2046 56 47 0 FALSE 1.21
non-small cell lung cancer KRAS_G12A RASA1 32 51 Male -6.97 -11.53 -0.95 2.49 1.56 1467 32 51 0 FALSE 1.21
colorectal cancer KRAS_G12A RASA1 53 73 Sex:overall 0.27 -1.74 1.80 1342.68 1.00 2177 50 70 3 FALSE 0.12
non-small cell lung cancer KRAS_G12A RASA1 88 98 Sex:overall -6.95 -11.32 -0.95 2.42 1.59 3513 88 98 0 FALSE 1.20
colorectal cancer KRAS_G12A EPHA5 22 58 Female -0.91 -3.40 0.97 227.08 1.01 977 22 58 0 FALSE 0.36
colorectal cancer KRAS_G12A EPHA5 29 86 Male -0.58 -2.37 0.98 136.42 1.04 1139 27 84 2 FALSE 0.31
non-small cell lung cancer KRAS_G12A EPHA5 57 147 Female -0.30 -1.40 0.52 200.16 1.02 1958 53 143 4 FALSE 0.25
non-small cell lung cancer KRAS_G12A EPHA5 32 113 Male -0.44 -1.80 0.47 210.66 1.02 1419 31 112 1 FALSE 0.34
colorectal cancer KRAS_G12A EPHA5 51 144 Sex:overall -0.72 -2.87 1.02 213.65 1.02 2116 49 142 2 FALSE 0.33
non-small cell lung cancer KRAS_G12A EPHA5 89 260 Sex:overall -0.38 -1.77 0.60 224.88 1.02 3377 84 255 5 FALSE 0.26
colorectal cancer KRAS_G12A AR 22 59 Female -1.63 -4.54 0.36 334.27 1.01 976 22 59 0 TRUE 0.69
colorectal cancer KRAS_G12A AR 29 57 Male -1.42 -4.25 0.49 422.08 1.01 1154 28 56 1 TRUE 0.62
non-small cell lung cancer KRAS_G12A AR 56 81 Female -0.49 -2.44 0.82 655.71 1.00 2021 54 79 2 TRUE 0.25
non-small cell lung cancer KRAS_G12A AR 32 29 Male -0.93 -4.20 0.86 698.27 1.01 1489 32 29 0 TRUE 0.30
colorectal cancer KRAS_G12A AR 51 116 Sex:overall -1.52 -4.45 0.49 343.96 1.01 2130 50 115 1 TRUE 0.65
non-small cell lung cancer KRAS_G12A AR 88 110 Sex:overall -0.65 -3.02 1.06 826.07 1.00 3510 86 108 2 TRUE 0.26
colorectal cancer KRAS_G12A GNAS 25 41 Female 0.12 -1.68 1.62 1268.71 1.00 1093 23 39 2 TRUE 0.05
colorectal cancer KRAS_G12A GNAS 31 34 Male -0.39 -3.16 1.19 1089.42 1.00 1298 31 34 0 TRUE 0.13
colorectal cancer KRAS_G12A GNAS 56 75 Sex:overall -0.12 -2.37 1.61 1139.83 1.00 2391 54 73 2 TRUE 0.04
colorectal cancer KRAS_G12A ASXL2 22 20 Female -4.75 -12.10 -0.05 1089.26 1.00 1009 22 20 0 FALSE 0.86
colorectal cancer KRAS_G12A ASXL2 29 51 Male -4.80 -12.20 -0.13 1143.88 1.00 1173 29 51 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A ASXL2 56 32 Female -0.52 -3.46 1.08 21.43 1.16 2062 55 31 1 FALSE 0.17
non-small cell lung cancer KRAS_G12A ASXL2 32 31 Male -0.68 -3.99 0.94 19.77 1.16 1488 32 31 0 FALSE 0.20
colorectal cancer KRAS_G12A ASXL2 51 71 Sex:overall -4.68 -11.64 -0.03 1136.90 1.00 2182 51 71 0 FALSE 0.89
non-small cell lung cancer KRAS_G12A ASXL2 88 63 Sex:overall -0.60 -3.73 1.02 20.83 1.16 3550 87 62 1 FALSE 0.19
colorectal cancer KRAS_G12A SF3B1 22 18 Female -1.21 -4.60 1.14 1266.48 1.00 1012 22 18 0 TRUE 0.36
colorectal cancer KRAS_G12A SF3B1 29 52 Male -0.90 -3.79 1.02 1043.63 1.00 1168 28 51 1 TRUE 0.34
non-small cell lung cancer KRAS_G12A SF3B1 56 55 Female 0.98 -0.10 1.85 1218.97 1.00 2043 53 52 3 TRUE 1.40
non-small cell lung cancer KRAS_G12A SF3B1 33 32 Male 1.14 0.16 2.09 894.47 1.00 1489 30 29 3 TRUE 1.62
colorectal cancer KRAS_G12A SF3B1 51 70 Sex:overall -1.01 -4.28 1.33 1307.60 1.00 2180 50 69 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A SF3B1 89 87 Sex:overall 1.06 -0.12 2.07 1129.05 1.00 3532 83 81 6 TRUE 1.21
colorectal cancer KRAS_G12A MLH1 25 20 Female -4.52 -11.52 -0.22 14.71 1.13 1112 25 20 0 TRUE 0.79
colorectal cancer KRAS_G12A MLH1 31 36 Male -4.52 -11.43 -0.25 13.20 1.14 1300 31 36 0 TRUE 0.79
colorectal cancer KRAS_G12A MLH1 56 56 Sex:overall -4.48 -11.41 -0.32 13.81 1.13 2412 56 56 0 TRUE 0.80
colorectal cancer KRAS_G12A ROS1 22 32 Female -4.89 -11.82 -0.36 1292.99 1.00 998 22 32 0 TRUE 0.97
colorectal cancer KRAS_G12A ROS1 29 71 Male -4.95 -11.65 -0.58 1315.15 1.00 1154 29 71 0 TRUE 1.03
non-small cell lung cancer KRAS_G12A ROS1 56 57 Female -0.16 -1.77 1.11 1108.27 1.00 2037 55 56 1 TRUE 0.08
non-small cell lung cancer KRAS_G12A ROS1 32 54 Male 0.06 -1.46 1.31 1030.52 1.00 1469 30 52 2 TRUE 0.03
colorectal cancer KRAS_G12A ROS1 51 103 Sex:overall -4.82 -11.55 -0.30 1269.77 1.00 2152 51 103 0 TRUE 0.98
non-small cell lung cancer KRAS_G12A ROS1 88 111 Sex:overall -0.04 -1.62 1.28 984.44 1.00 3506 85 108 3 TRUE 0.02
colorectal cancer KRAS_G12A PIK3R2 22 24 Female -0.44 -3.42 1.53 687.18 1.00 1008 21 23 1 FALSE 0.14
colorectal cancer KRAS_G12A PIK3R2 29 28 Male -0.73 -4.26 1.30 520.76 1.00 1177 29 28 0 FALSE 0.22
colorectal cancer KRAS_G12A PIK3R2 51 52 Sex:overall -0.57 -3.67 1.41 645.89 1.00 2185 50 51 1 FALSE 0.18
colorectal cancer KRAS_G12A FLT3 25 19 Female -4.47 -13.84 0.23 54.57 1.06 1109 25 19 0 TRUE 0.72
colorectal cancer KRAS_G12A FLT3 31 33 Male -4.49 -13.79 0.02 50.53 1.06 1307 31 33 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A FLT3 58 42 Female -0.24 -1.96 1.04 557.70 1.00 2117 57 41 1 TRUE 0.12
non-small cell lung cancer KRAS_G12A FLT3 33 39 Male -0.20 -1.90 1.12 501.84 1.01 1539 32 38 1 TRUE 0.10
colorectal cancer KRAS_G12A FLT3 56 52 Sex:overall -4.42 -13.79 0.11 50.69 1.06 2416 56 52 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A FLT3 91 81 Sex:overall -0.23 -2.06 1.12 729.29 1.00 3656 89 79 2 TRUE 0.11
colorectal cancer KRAS_G12A MSH2 22 34 Female -1.25 -4.50 0.71 883.50 1.00 1003 22 34 0 TRUE 0.43
colorectal cancer KRAS_G12A MSH2 29 49 Male -1.00 -3.87 0.82 1027.42 1.00 1169 28 48 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A MSH2 56 26 Female -4.51 -11.51 0.00 593.40 1.00 2065 56 26 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A MSH2 32 30 Male -4.48 -11.55 0.16 641.43 1.00 1492 32 30 0 TRUE 0.85
colorectal cancer KRAS_G12A MSH2 51 83 Sex:overall -1.10 -4.11 0.89 1143.98 1.00 2172 50 82 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A MSH2 88 56 Sex:overall -4.42 -11.43 0.14 550.67 1.00 3557 88 56 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A DIS3 56 29 Female 0.40 -1.24 1.68 1465.29 1.00 2063 55 28 1 FALSE 0.23
non-small cell lung cancer KRAS_G12A DIS3 32 36 Male 0.61 -0.92 1.87 1465.92 1.00 1486 30 34 2 FALSE 0.41
non-small cell lung cancer KRAS_G12A DIS3 88 65 Sex:overall 0.50 -1.23 1.97 1598.60 1.00 3549 85 62 3 FALSE 0.28
colorectal cancer KRAS_G12A AXL 22 30 Female -1.44 -4.87 0.75 1219.97 1.00 1000 22 30 0 FALSE 0.51
colorectal cancer KRAS_G12A AXL 29 58 Male -1.17 -3.92 0.69 1294.46 1.00 1160 28 57 1 FALSE 0.48
colorectal cancer KRAS_G12A AXL 51 88 Sex:overall -1.28 -4.20 0.87 1162.11 1.00 2160 50 87 1 FALSE 0.48
colorectal cancer KRAS_G12A PIK3CG 22 39 Female -0.43 -3.38 1.14 1107.63 1.00 991 22 39 0 FALSE 0.13
colorectal cancer KRAS_G12A PIK3CG 29 68 Male 0.22 -1.24 1.43 1157.02 1.00 1152 26 65 3 FALSE 0.13
non-small cell lung cancer KRAS_G12A PIK3CG 56 88 Female 0.30 -0.73 1.10 908.91 1.02 2011 53 85 3 FALSE 0.30
non-small cell lung cancer KRAS_G12A PIK3CG 33 92 Male 0.33 -0.78 1.16 942.34 1.01 1442 30 89 3 FALSE 0.32
colorectal cancer KRAS_G12A PIK3CG 51 107 Sex:overall -0.14 -2.55 1.43 1114.74 1.00 2143 48 104 3 FALSE 0.05
non-small cell lung cancer KRAS_G12A PIK3CG 89 180 Sex:overall 0.33 -0.86 1.31 1049.92 1.01 3453 83 174 6 FALSE 0.27
colorectal cancer KRAS_G12A MAP2K4 22 28 Female -0.15 -2.50 1.40 137.04 1.02 1001 22 28 0 TRUE 0.04
colorectal cancer KRAS_G12A MAP2K4 29 35 Male 0.18 -1.78 1.56 103.53 1.03 1173 27 33 2 TRUE 0.08
colorectal cancer KRAS_G12A MAP2K4 51 63 Sex:overall 0.04 -1.92 1.68 125.98 1.02 2174 49 61 2 TRUE 0.01
colorectal cancer KRAS_G12A EGFR 25 28 Female -4.44 -10.78 -0.31 270.46 1.01 1102 25 28 0 TRUE 0.93
colorectal cancer KRAS_G12A EGFR 31 38 Male -4.46 -10.77 -0.33 275.37 1.01 1298 31 38 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A EGFR 58 724 Female -4.37 -8.06 -2.31 1350.21 1.00 1567 58 724 0 TRUE 2.42
non-small cell lung cancer KRAS_G12A EGFR 33 318 Male -3.46 -6.30 -1.19 1364.71 1.00 1309 32 317 1 TRUE 2.10
colorectal cancer KRAS_G12A EGFR 56 66 Sex:overall -4.41 -10.61 -0.35 277.72 1.01 2400 56 66 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A EGFR 91 1042 Sex:overall -3.80 -6.68 -1.43 1372.13 1.00 2876 90 1041 1 TRUE 2.21
colorectal cancer KRAS_G12A ARID1B 22 70 Female -1.58 -4.14 0.36 721.67 1.00 970 21 69 1 TRUE 0.76
colorectal cancer KRAS_G12A ARID1B 29 70 Male -1.86 -4.86 0.18 723.25 1.00 1146 29 70 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A ARID1B 56 68 Female 0.37 -1.01 1.20 38.95 1.06 2028 54 66 2 TRUE 0.26
non-small cell lung cancer KRAS_G12A ARID1B 32 43 Male 0.47 -0.96 1.50 95.29 1.03 1480 30 41 2 TRUE 0.35
colorectal cancer KRAS_G12A ARID1B 51 140 Sex:overall -1.71 -4.47 0.30 730.69 1.00 2116 50 139 1 TRUE 0.77
non-small cell lung cancer KRAS_G12A ARID1B 88 111 Sex:overall 0.42 -1.10 1.42 75.73 1.03 3508 84 107 4 TRUE 0.27
non-small cell lung cancer KRAS_G12A INSR 56 33 Female -0.97 -4.07 1.02 1065.56 1.00 2048 56 33 0 FALSE 0.32
non-small cell lung cancer KRAS_G12A INSR 32 22 Male -0.68 -3.23 1.24 795.96 1.00 1493 31 21 1 FALSE 0.24
non-small cell lung cancer KRAS_G12A INSR 88 55 Sex:overall -0.80 -3.77 1.16 898.10 1.00 3541 87 54 1 FALSE 0.28
non-small cell lung cancer KRAS_G12A NKX2-1 56 34 Female 1.16 -0.20 2.31 1069.90 1.00 2064 52 30 4 TRUE 1.13
non-small cell lung cancer KRAS_G12A NKX2-1 32 41 Male -0.46 -4.92 1.52 1248.44 1.00 1484 32 41 0 TRUE 0.10
non-small cell lung cancer KRAS_G12A NKX2-1 88 75 Sex:overall 0.38 -2.49 2.37 1432.68 1.00 3548 84 71 4 TRUE 0.11
colorectal cancer KRAS_G12A ARID5B 22 20 Female -0.51 -3.73 1.45 1293.96 1.00 1009 22 20 0 FALSE 0.15
colorectal cancer KRAS_G12A ARID5B 29 48 Male 0.09 -1.71 1.52 1399.33 1.00 1171 27 46 2 FALSE 0.04
colorectal cancer KRAS_G12A ARID5B 51 68 Sex:overall -0.18 -2.65 1.75 1438.68 1.00 2180 49 66 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A WT1 56 39 Female -0.88 -3.61 0.72 568.82 1.01 2055 55 38 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A WT1 32 31 Male -0.99 -3.94 0.80 348.41 1.02 1489 32 31 0 TRUE 0.39
non-small cell lung cancer KRAS_G12A WT1 88 70 Sex:overall -0.91 -3.75 0.87 392.93 1.01 3544 87 69 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A MET 58 94 Female -0.54 -2.12 0.59 1115.98 1.00 2072 57 93 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A MET 33 71 Male -0.37 -1.76 0.80 965.19 1.00 1512 31 69 2 TRUE 0.26
non-small cell lung cancer KRAS_G12A MET 91 165 Sex:overall -0.46 -1.98 0.72 1183.54 1.00 3584 88 162 3 TRUE 0.32
non-small cell lung cancer KRAS_G12A PMS1 56 29 Female -0.08 -3.42 1.38 767.27 1.02 2063 56 29 0 TRUE 0.02
non-small cell lung cancer KRAS_G12A PMS1 32 23 Male 0.50 -1.29 2.07 971.78 1.00 1497 30 21 2 TRUE 0.27
non-small cell lung cancer KRAS_G12A PMS1 88 52 Sex:overall 0.24 -2.03 1.83 774.07 1.01 3560 86 50 2 TRUE 0.09
non-small cell lung cancer KRAS_G12A PIK3C3 56 40 Female 0.77 -0.45 1.81 1346.38 1.00 2044 53 37 3 FALSE 0.71
non-small cell lung cancer KRAS_G12A PIK3C3 32 36 Male 0.63 -0.74 1.74 1246.07 1.00 1478 31 35 1 FALSE 0.47
non-small cell lung cancer KRAS_G12A PIK3C3 88 76 Sex:overall 0.71 -0.64 1.84 1268.63 1.00 3522 84 72 4 FALSE 0.56
colorectal cancer KRAS_G12A BRAF 25 128 Female -2.11 -4.75 -0.32 1522.64 1.00 1007 24 127 1 TRUE 1.22
colorectal cancer KRAS_G12A BRAF 31 125 Male -2.32 -5.19 -0.49 1379.56 1.00 1213 31 125 0 TRUE 1.26
non-small cell lung cancer KRAS_G12A BRAF 58 113 Female -2.08 -4.66 -0.29 177.85 1.02 2045 57 112 1 TRUE 1.10
non-small cell lung cancer KRAS_G12A BRAF 33 80 Male -2.19 -5.10 -0.26 206.77 1.01 1497 33 80 0 TRUE 1.03
colorectal cancer KRAS_G12A BRAF 56 253 Sex:overall -2.21 -4.89 -0.40 1511.65 1.00 2220 55 252 1 TRUE 1.18
non-small cell lung cancer KRAS_G12A BRAF 91 193 Sex:overall -2.12 -4.86 -0.23 207.11 1.02 3542 90 192 1 TRUE 1.05
non-small cell lung cancer KRAS_G12A TGFBR1 56 36 Female 0.74 -0.77 1.89 1184.14 1.00 2045 54 34 2 FALSE 0.55
non-small cell lung cancer KRAS_G12A TGFBR1 32 15 Male 0.80 -0.79 2.11 1228.62 1.00 1499 31 14 1 FALSE 0.51
non-small cell lung cancer KRAS_G12A TGFBR1 88 51 Sex:overall 0.75 -0.97 2.18 1307.96 1.00 3544 85 48 3 FALSE 0.44
colorectal cancer KRAS_G12A TET2 22 31 Female -1.52 -4.62 0.61 1231.59 1.00 1002 22 31 0 TRUE 0.55
colorectal cancer KRAS_G12A TET2 29 60 Male -1.28 -3.93 0.74 506.51 1.00 1158 28 59 1 TRUE 0.58
non-small cell lung cancer KRAS_G12A TET2 56 38 Female -1.01 -3.62 0.82 1321.89 1.00 2055 55 37 1 TRUE 0.41
non-small cell lung cancer KRAS_G12A TET2 32 43 Male -1.34 -4.55 0.66 1286.15 1.00 1479 32 43 0 TRUE 0.48
colorectal cancer KRAS_G12A TET2 51 91 Sex:overall -1.35 -4.24 0.76 985.83 1.00 2160 50 90 1 TRUE 0.54
non-small cell lung cancer KRAS_G12A TET2 88 81 Sex:overall -1.16 -3.85 0.83 1343.27 1.00 3534 87 80 1 TRUE 0.46
colorectal cancer KRAS_G12A PDGFRB 22 24 Female -0.72 -3.00 1.26 34.65 1.05 1005 21 23 1 TRUE 0.31
colorectal cancer KRAS_G12A PDGFRB 29 28 Male -0.90 -3.28 1.09 476.30 1.01 1177 29 28 0 TRUE 0.38
non-small cell lung cancer KRAS_G12A PDGFRB 56 54 Female -0.30 -2.26 1.04 794.92 1.00 2045 54 52 2 TRUE 0.15
non-small cell lung cancer KRAS_G12A PDGFRB 32 38 Male -0.57 -3.02 0.90 919.79 1.00 1483 32 38 0 TRUE 0.22
colorectal cancer KRAS_G12A PDGFRB 51 52 Sex:overall -0.82 -3.11 1.15 89.96 1.03 2182 50 51 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A PDGFRB 88 92 Sex:overall -0.41 -2.61 1.08 915.19 1.00 3528 86 90 2 TRUE 0.18
colorectal cancer KRAS_G12A CARD11 22 49 Female 0.51 -0.79 1.57 1708.44 1.00 983 20 47 2 FALSE 0.41
colorectal cancer KRAS_G12A CARD11 30 79 Male 0.46 -0.67 1.41 1661.41 1.00 1138 27 76 3 FALSE 0.41
non-small cell lung cancer KRAS_G12A CARD11 56 71 Female 0.13 -1.07 1.17 911.87 1.00 2025 54 69 2 FALSE 0.09
non-small cell lung cancer KRAS_G12A CARD11 32 59 Male 0.20 -1.03 1.25 884.95 1.00 1465 30 57 2 FALSE 0.13
colorectal cancer KRAS_G12A CARD11 52 128 Sex:overall 0.48 -0.87 1.59 1585.71 1.00 2121 47 123 5 FALSE 0.35
non-small cell lung cancer KRAS_G12A CARD11 88 130 Sex:overall 0.17 -1.08 1.28 900.96 1.00 3490 84 126 4 FALSE 0.11
colorectal cancer KRAS_G12A DNMT3A 22 24 Female -4.78 -11.39 -0.04 99.21 1.03 1008 22 24 0 TRUE 0.89
colorectal cancer KRAS_G12A DNMT3A 29 32 Male -4.77 -11.39 -0.07 101.59 1.03 1175 29 32 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A DNMT3A 56 49 Female -4.75 -11.22 -0.31 157.11 1.02 2043 56 49 0 TRUE 0.92
non-small cell lung cancer KRAS_G12A DNMT3A 32 28 Male -4.74 -11.22 -0.26 134.42 1.02 1490 32 28 0 TRUE 0.92
colorectal cancer KRAS_G12A DNMT3A 51 56 Sex:overall -4.74 -11.36 -0.01 99.85 1.03 2183 51 56 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A DNMT3A 88 77 Sex:overall -4.71 -11.13 -0.33 153.85 1.02 3533 88 77 0 TRUE 0.92
colorectal cancer KRAS_G12A MSH6 22 43 Female -0.49 -3.01 0.96 124.64 1.03 990 22 43 0 TRUE 0.18
colorectal cancer KRAS_G12A MSH6 29 57 Male -0.20 -2.06 1.06 299.74 1.02 1163 27 55 2 TRUE 0.09
colorectal cancer KRAS_G12A MSH6 51 100 Sex:overall -0.33 -2.48 1.07 177.51 1.02 2153 49 98 2 TRUE 0.13
non-small cell lung cancer KRAS_G12A MAX 56 35 Female 1.31 0.32 2.30 73.92 1.04 2049 52 31 4 FALSE 2.03
non-small cell lung cancer KRAS_G12A MAX 32 20 Male 1.16 -0.28 2.25 1048.47 1.01 1494 31 19 1 FALSE 1.18
non-small cell lung cancer KRAS_G12A MAX 88 55 Sex:overall 1.23 -0.04 2.48 416.35 1.02 3543 83 50 5 FALSE 1.28
non-small cell lung cancer KRAS_G12A INPP4B 56 60 Female 0.48 -0.63 1.41 1344.19 1.00 2037 53 57 3 FALSE 0.45
non-small cell lung cancer KRAS_G12A INPP4B 32 66 Male 0.40 -0.82 1.37 1253.75 1.00 1462 30 64 2 FALSE 0.33
non-small cell lung cancer KRAS_G12A INPP4B 88 126 Sex:overall 0.44 -1.00 1.68 1253.26 1.00 3499 83 121 5 FALSE 0.29
non-small cell lung cancer KRAS_G12A NFE2L2 56 52 Female -1.39 -4.18 0.50 1414.39 1.00 2044 55 51 1 FALSE 0.59
non-small cell lung cancer KRAS_G12A NFE2L2 32 72 Male -1.98 -5.62 0.16 1316.50 1.00 1455 32 72 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A NFE2L2 88 124 Sex:overall -1.69 -4.77 0.51 1440.92 1.00 3499 87 123 1 FALSE 0.65
colorectal cancer KRAS_G12A SOX9 23 125 Female 0.61 -0.22 1.36 1128.83 1.00 917 19 121 4 FALSE 0.88
colorectal cancer KRAS_G12A SOX9 31 139 Male 0.69 -0.10 1.38 1029.79 1.00 1084 24 132 7 FALSE 1.18
colorectal cancer KRAS_G12A SOX9 54 264 Sex:overall 0.66 -0.19 1.41 1194.71 1.00 2001 43 253 11 FALSE 0.87
colorectal cancer KRAS_G12A ARAF 22 30 Female -4.25 -10.86 -0.17 135.18 1.02 1002 22 30 0 FALSE 0.97
colorectal cancer KRAS_G12A ARAF 29 25 Male -4.31 -10.57 -0.22 124.51 1.03 1181 29 25 0 FALSE 0.99
non-small cell lung cancer KRAS_G12A ARAF 56 55 Female -0.04 -1.79 1.31 1125.54 1.00 2047 54 53 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A ARAF 32 14 Male -0.72 -4.58 1.54 1130.70 1.00 1504 32 14 0 FALSE 0.18
colorectal cancer KRAS_G12A ARAF 51 55 Sex:overall -4.25 -10.21 -0.16 159.10 1.02 2183 51 55 0 FALSE 0.99
non-small cell lung cancer KRAS_G12A ARAF 88 69 Sex:overall -0.36 -3.28 1.73 1015.54 1.00 3551 86 67 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A JAK2 58 33 Female -0.75 -4.49 1.03 1293.02 1.00 2123 58 33 0 TRUE 0.23
non-small cell lung cancer KRAS_G12A JAK2 34 45 Male 0.07 -1.97 1.56 1497.82 1.00 1534 32 43 2 TRUE 0.03
non-small cell lung cancer KRAS_G12A JAK2 92 78 Sex:overall -0.34 -3.04 1.47 1413.30 1.00 3657 90 76 2 TRUE 0.11
colorectal cancer KRAS_G12A SMAD2 22 43 Female -0.49 -2.61 1.40 20.80 1.17 991 20 41 2 TRUE 0.17
colorectal cancer KRAS_G12A SMAD2 29 59 Male -1.13 -3.86 0.86 82.94 1.04 1153 29 59 0 TRUE 0.34
colorectal cancer KRAS_G12A SMAD2 51 102 Sex:overall -0.78 -2.74 1.21 36.25 1.09 2144 49 100 2 TRUE 0.28
non-small cell lung cancer KRAS_G12A TP63 56 34 Female -0.96 -4.02 1.01 1467.85 1.00 2048 55 33 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A TP63 32 38 Male -1.31 -4.98 0.74 1355.10 1.00 1475 32 38 0 FALSE 0.43
non-small cell lung cancer KRAS_G12A TP63 88 72 Sex:overall -1.12 -4.43 1.03 1483.11 1.00 3523 87 71 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A MYOD1 56 29 Female -4.23 -11.08 -0.05 684.04 1.00 2054 56 29 0 FALSE 0.83
non-small cell lung cancer KRAS_G12A MYOD1 32 29 Male -4.22 -10.81 0.09 743.84 1.00 1484 32 29 0 FALSE 0.82
non-small cell lung cancer KRAS_G12A MYOD1 88 58 Sex:overall -4.19 -10.82 -0.03 764.03 1.00 3538 88 58 0 FALSE 0.83
colorectal cancer KRAS_G12A FGFR1 25 21 Female -4.21 -11.63 0.25 374.01 1.00 1107 25 21 0 TRUE 0.73
colorectal cancer KRAS_G12A FGFR1 31 30 Male -4.19 -11.42 0.15 348.49 1.00 1307 31 30 0 TRUE 0.74
colorectal cancer KRAS_G12A FGFR1 56 51 Sex:overall -4.16 -11.57 0.15 375.32 1.00 2414 56 51 0 TRUE 0.73
colorectal cancer KRAS_G12A MITF 22 22 Female -4.24 -10.58 0.21 196.25 1.01 1006 22 22 0 FALSE 0.81
colorectal cancer KRAS_G12A MITF 29 30 Male -4.26 -10.62 0.19 205.23 1.01 1175 29 30 0 FALSE 0.81
colorectal cancer KRAS_G12A MITF 51 52 Sex:overall -4.22 -10.42 0.19 197.00 1.01 2181 51 52 0 FALSE 0.81
non-small cell lung cancer KRAS_G12A BTK 56 47 Female -4.68 -11.71 -0.15 905.98 1.00 2045 56 47 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A BTK 32 13 Male -4.54 -11.67 0.24 1134.22 1.00 1505 32 13 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A BTK 88 60 Sex:overall -4.45 -11.21 0.34 993.72 1.00 3550 88 60 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A GLI1 51 56 Female -1.32 -4.18 0.41 609.01 1.00 1840 50 55 1 FALSE 0.60
non-small cell lung cancer KRAS_G12A GLI1 32 50 Male -1.47 -4.53 0.38 557.53 1.00 1313 32 50 0 FALSE 0.62
non-small cell lung cancer KRAS_G12A GLI1 83 106 Sex:overall -1.38 -4.43 0.44 615.78 1.00 3153 82 105 1 FALSE 0.60
non-small cell lung cancer KRAS_G12A ZFHX3 51 90 Female 0.10 -0.91 1.05 946.70 1.00 1810 48 87 3 FALSE 0.08
non-small cell lung cancer KRAS_G12A ZFHX3 32 74 Male 0.07 -1.03 1.05 1052.06 1.00 1288 30 72 2 FALSE 0.05
non-small cell lung cancer KRAS_G12A ZFHX3 83 164 Sex:overall 0.09 -1.05 1.18 1370.42 1.00 3098 78 159 5 FALSE 0.06
non-small cell lung cancer KRAS_G12A MGA 51 117 Female -0.22 -1.55 0.75 110.39 1.02 1800 49 115 2 FALSE 0.15
non-small cell lung cancer KRAS_G12A MGA 32 80 Male -0.08 -1.58 1.04 93.22 1.03 1282 29 77 3 FALSE 0.04
non-small cell lung cancer KRAS_G12A MGA 83 197 Sex:overall -0.16 -1.56 0.92 112.43 1.02 3082 78 192 5 FALSE 0.09
non-small cell lung cancer KRAS_G12A ANKRD11 51 40 Female -0.15 -1.97 1.34 472.37 1.01 1847 49 38 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A ANKRD11 32 32 Male -0.41 -2.73 1.15 700.38 1.00 1321 32 32 0 FALSE 0.16
non-small cell lung cancer KRAS_G12A ANKRD11 83 72 Sex:overall -0.26 -2.31 1.36 566.94 1.01 3168 81 70 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A PGR 51 44 Female -1.26 -4.13 0.68 1018.55 1.00 1839 50 43 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A PGR 32 43 Male -1.52 -4.68 0.59 1005.57 1.00 1312 32 43 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A PGR 83 87 Sex:overall -1.38 -4.42 0.69 1098.03 1.00 3151 82 86 1 FALSE 0.54
non-small cell lung cancer KRAS_G12A PLCG2 51 31 Female -0.88 -3.66 0.99 1159.26 1.01 1855 50 30 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A PLCG2 32 31 Male -1.16 -4.29 0.93 1091.38 1.00 1325 32 31 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A PLCG2 83 62 Sex:overall -1.00 -4.12 1.03 1231.29 1.00 3180 82 61 1 FALSE 0.34
non-small cell lung cancer KRAS_G12A POLD1 51 31 Female -4.85 -12.84 -0.25 64.76 1.02 1863 51 31 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A POLD1 32 27 Male -4.83 -12.88 -0.19 61.15 1.03 1331 32 27 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A POLD1 83 58 Sex:overall -4.79 -12.88 -0.13 61.75 1.03 3194 83 58 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A INHBA 51 46 Female -1.42 -4.78 0.49 1035.64 1.00 1851 51 46 0 FALSE 0.53
non-small cell lung cancer KRAS_G12A INHBA 32 41 Male -1.14 -3.91 0.76 972.95 1.00 1320 31 40 1 FALSE 0.46
non-small cell lung cancer KRAS_G12A INHBA 83 87 Sex:overall -1.27 -4.17 0.68 870.20 1.00 3171 82 86 1 FALSE 0.51
colorectal cancer KRAS_G12A AMER1 22 85 Female -1.95 -4.01 0.04 20.22 1.06 952 21 84 1 FALSE 1.36
colorectal cancer KRAS_G12A AMER1 29 84 Male -2.09 -4.55 -0.14 307.13 1.02 1126 29 84 0 FALSE 1.34
non-small cell lung cancer KRAS_G12A AMER1 56 104 Female 0.29 -0.76 1.16 1383.10 1.00 2008 52 100 4 FALSE 0.26
non-small cell lung cancer KRAS_G12A AMER1 32 45 Male 0.11 -1.44 1.24 1558.71 1.00 1478 31 44 1 FALSE 0.06
colorectal cancer KRAS_G12A AMER1 51 169 Sex:overall -2.01 -4.13 -0.08 51.66 1.05 2078 50 168 1 FALSE 1.43
non-small cell lung cancer KRAS_G12A AMER1 88 149 Sex:overall 0.20 -1.18 1.38 1601.32 1.00 3486 83 144 5 FALSE 0.12
non-small cell lung cancer KRAS_G12A EPHA7 51 67 Female -0.72 -2.38 0.74 445.72 1.00 1830 49 65 2 FALSE 0.42
non-small cell lung cancer KRAS_G12A EPHA7 32 62 Male -1.11 -3.64 0.56 945.81 1.00 1300 32 62 0 FALSE 0.51
non-small cell lung cancer KRAS_G12A EPHA7 83 129 Sex:overall -0.90 -2.85 0.70 871.55 1.00 3130 81 127 2 FALSE 0.46
colorectal cancer KRAS_G12C SPEN 41 55 Female -5.39 -11.91 -1.21 908.44 1.00 966 41 55 0 FALSE 1.22
colorectal cancer KRAS_G12C SPEN 29 100 Male -5.44 -12.07 -1.24 890.62 1.00 1134 29 100 0 FALSE 1.22
non-small cell lung cancer KRAS_G12C SPEN 284 56 Female -0.76 -1.66 0.02 1376.59 1.00 1819 279 51 5 FALSE 1.08
non-small cell lung cancer KRAS_G12C SPEN 172 65 Male -1.08 -2.30 -0.16 1224.75 1.00 1340 170 63 2 FALSE 1.36
colorectal cancer KRAS_G12C SPEN 70 155 Sex:overall -5.28 -11.79 -1.10 860.58 1.00 2100 70 155 0 FALSE 1.21
non-small cell lung cancer KRAS_G12C SPEN 456 121 Sex:overall -0.90 -2.15 0.18 1445.33 1.00 3159 449 114 7 FALSE 0.81
colorectal cancer KRAS_G12C KMT2C 38 68 Female -5.61 -12.52 -1.48 532.42 1.00 923 38 68 0 FALSE 1.20
colorectal cancer KRAS_G12C KMT2C 28 130 Male -5.59 -12.54 -1.46 518.26 1.00 1088 28 130 0 FALSE 1.21
non-small cell lung cancer KRAS_G12C KMT2C 284 113 Female 0.17 -0.31 0.64 1452.87 1.00 1766 265 94 19 FALSE 0.30
non-small cell lung cancer KRAS_G12C KMT2C 172 109 Male -0.08 -0.70 0.44 1670.06 1.00 1283 162 99 10 FALSE 0.11
colorectal cancer KRAS_G12C KMT2C 66 198 Sex:overall -5.47 -12.30 -1.23 546.51 1.00 2011 66 198 0 FALSE 1.23
non-small cell lung cancer KRAS_G12C KMT2C 456 222 Sex:overall 0.04 -0.72 0.84 1518.85 1.00 3049 427 193 29 FALSE 0.04
colorectal cancer KRAS_G12C TP53 50 796 Female -0.34 -0.84 0.16 1439.78 1.00 395 21 767 29 TRUE 0.75
colorectal cancer KRAS_G12C TP53 34 923 Male -0.50 -1.04 0.03 1439.55 1.00 488 16 905 18 TRUE 1.16
non-small cell lung cancer KRAS_G12C TP53 301 1120 Female -0.51 -0.74 -0.26 1262.16 1.00 990 184 1003 117 TRUE 4.38
non-small cell lung cancer KRAS_G12C TP53 181 936 Male -0.89 -1.22 -0.59 1328.57 1.00 619 118 873 63 TRUE 7.58
colorectal cancer KRAS_G12C TP53 84 1719 Sex:overall -0.41 -1.23 0.48 1559.13 1.00 883 37 1672 47 TRUE 0.46
non-small cell lung cancer KRAS_G12C TP53 482 2056 Sex:overall -0.70 -1.50 0.08 1359.68 1.00 1609 302 1876 180 TRUE 1.12
colorectal cancer KRAS_G12C ATRX 41 73 Female -1.81 -4.68 0.04 1439.55 1.00 949 40 72 1 TRUE 0.92
colorectal cancer KRAS_G12C ATRX 29 46 Male -2.19 -5.56 0.06 1369.03 1.00 1167 29 46 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C ATRX 287 162 Female 0.78 0.40 1.15 1572.92 1.00 1763 248 123 39 TRUE 4.12
non-small cell lung cancer KRAS_G12C ATRX 173 46 Male 0.08 -0.86 0.82 1504.59 1.00 1338 168 41 5 TRUE 0.07
colorectal cancer KRAS_G12C ATRX 70 119 Sex:overall -1.94 -4.85 0.47 1473.10 1.00 2116 69 118 1 TRUE 0.82
non-small cell lung cancer KRAS_G12C ATRX 460 208 Sex:overall 0.41 -1.08 1.71 1257.75 1.00 3101 416 164 44 TRUE 0.26
colorectal cancer KRAS_G12C ATR 41 30 Female -5.28 -12.53 -0.63 1074.83 1.00 981 41 30 0 FALSE 1.07
colorectal cancer KRAS_G12C ATR 29 84 Male -5.37 -12.97 -0.99 1067.16 1.00 1149 29 84 0 FALSE 1.11
non-small cell lung cancer KRAS_G12C ATR 283 69 Female 0.10 -0.47 0.64 1242.48 1.00 1808 273 59 10 FALSE 0.15
non-small cell lung cancer KRAS_G12C ATR 172 60 Male 0.12 -0.47 0.70 1076.61 1.00 1328 164 52 8 FALSE 0.17
colorectal cancer KRAS_G12C ATR 70 114 Sex:overall -5.16 -12.26 -0.60 1075.68 1.00 2130 70 114 0 FALSE 1.08
non-small cell lung cancer KRAS_G12C ATR 455 129 Sex:overall 0.12 -0.55 0.81 981.83 1.01 3136 437 111 18 FALSE 0.14
colorectal cancer KRAS_G12C PDGFRA 48 28 Female 0.11 -1.53 1.35 1337.80 1.00 1077 47 27 1 TRUE 0.05
colorectal cancer KRAS_G12C PDGFRA 33 32 Male 0.43 -1.01 1.77 1121.84 1.00 1305 31 30 2 TRUE 0.26
non-small cell lung cancer KRAS_G12C PDGFRA 294 69 Female 1.13 0.56 1.67 1315.62 1.00 1878 271 46 23 TRUE 4.09
non-small cell lung cancer KRAS_G12C PDGFRA 179 79 Male -0.45 -1.47 0.39 1533.17 1.00 1360 174 74 5 TRUE 0.48
colorectal cancer KRAS_G12C PDGFRA 81 60 Sex:overall 0.25 -1.45 1.66 1326.82 1.00 2382 78 57 3 TRUE 0.12
non-small cell lung cancer KRAS_G12C PDGFRA 473 148 Sex:overall 0.33 -1.56 2.04 1385.97 1.00 3238 445 120 28 TRUE 0.14
colorectal cancer KRAS_G12C FBXW7 49 137 Female -0.30 -1.26 0.54 1445.05 1.00 987 45 133 4 TRUE 0.29
colorectal cancer KRAS_G12C FBXW7 34 202 Male -0.03 -0.90 0.74 1433.23 1.00 1160 28 196 6 TRUE 0.02
non-small cell lung cancer KRAS_G12C FBXW7 294 39 Female 0.01 -0.82 0.89 1175.87 1.00 1892 287 32 7 TRUE 0.01
non-small cell lung cancer KRAS_G12C FBXW7 180 47 Male -0.62 -2.06 0.29 1257.39 1.00 1385 178 45 2 TRUE 0.54
colorectal cancer KRAS_G12C FBXW7 83 339 Sex:overall -0.15 -1.29 0.90 1395.62 1.00 2147 73 329 10 TRUE 0.10
non-small cell lung cancer KRAS_G12C FBXW7 474 86 Sex:overall -0.29 -1.59 0.91 1381.59 1.00 3277 465 77 9 TRUE 0.19
colorectal cancer KRAS_G12C MAP3K1 41 39 Female -0.64 -2.50 0.81 1156.84 1.00 976 40 38 1 FALSE 0.35
colorectal cancer KRAS_G12C MAP3K1 29 53 Male -0.63 -2.53 0.91 1117.94 1.00 1158 28 52 1 FALSE 0.32
non-small cell lung cancer KRAS_G12C MAP3K1 283 39 Female 0.97 0.26 1.63 1186.57 1.00 1840 270 26 13 FALSE 2.31
non-small cell lung cancer KRAS_G12C MAP3K1 172 28 Male 0.51 -0.66 1.26 1063.39 1.00 1353 169 25 3 FALSE 0.53
colorectal cancer KRAS_G12C MAP3K1 70 92 Sex:overall -0.64 -2.55 0.89 1076.31 1.00 2134 68 90 2 FALSE 0.32
non-small cell lung cancer KRAS_G12C MAP3K1 455 67 Sex:overall 0.73 -0.39 1.55 1424.55 1.00 3193 439 51 16 FALSE 0.79
colorectal cancer KRAS_G12C NSD1 41 35 Female -1.75 -5.03 0.33 988.33 1.00 979 41 35 0 FALSE 0.68
colorectal cancer KRAS_G12C NSD1 29 51 Male -1.37 -3.88 0.52 948.55 1.01 1163 28 50 1 FALSE 0.62
non-small cell lung cancer KRAS_G12C NSD1 283 50 Female -0.06 -0.84 0.62 1278.19 1.00 1823 275 42 8 FALSE 0.06
non-small cell lung cancer KRAS_G12C NSD1 172 40 Male -0.36 -1.45 0.39 1391.79 1.00 1340 170 38 2 FALSE 0.35
colorectal cancer KRAS_G12C NSD1 70 86 Sex:overall -1.53 -4.42 0.55 1058.00 1.00 2142 69 85 1 FALSE 0.65
non-small cell lung cancer KRAS_G12C NSD1 455 90 Sex:overall -0.21 -1.28 0.64 1430.91 1.00 3163 445 80 10 FALSE 0.17
colorectal cancer KRAS_G12C FLT4 41 70 Female -1.91 -4.46 -0.07 1282.66 1.00 950 40 69 1 TRUE 0.99
colorectal cancer KRAS_G12C FLT4 29 69 Male -2.20 -5.66 -0.10 1184.98 1.00 1143 29 69 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C FLT4 284 47 Female 0.50 -0.15 1.16 1307.38 1.00 1830 273 36 11 TRUE 0.86
non-small cell lung cancer KRAS_G12C FLT4 172 55 Male 0.16 -0.66 0.83 1352.46 1.00 1330 166 49 6 TRUE 0.18
colorectal cancer KRAS_G12C FLT4 70 139 Sex:overall -2.03 -4.68 0.03 1292.19 1.00 2093 69 138 1 TRUE 1.00
non-small cell lung cancer KRAS_G12C FLT4 456 102 Sex:overall 0.33 -0.79 1.43 1509.97 1.00 3160 439 85 17 TRUE 0.25
colorectal cancer KRAS_G12C PTPRD 41 48 Female -1.53 -4.09 0.23 1030.03 1.00 968 40 47 1 FALSE 0.74
colorectal cancer KRAS_G12C PTPRD 29 55 Male -1.86 -5.10 0.19 1237.97 1.00 1164 29 55 0 FALSE 0.69
non-small cell lung cancer KRAS_G12C PTPRD 290 235 Female 0.30 -0.03 0.61 797.33 1.00 1708 248 193 42 FALSE 1.40
non-small cell lung cancer KRAS_G12C PTPRD 175 156 Male 0.13 -0.36 0.47 14.54 1.07 1251 159 140 16 FALSE 0.28
colorectal cancer KRAS_G12C PTPRD 70 103 Sex:overall -1.66 -4.31 0.27 992.24 1.00 2132 69 102 1 FALSE 0.76
non-small cell lung cancer KRAS_G12C PTPRD 465 391 Sex:overall 0.22 -0.26 0.66 1576.72 1.00 2959 407 333 58 FALSE 0.36
colorectal cancer KRAS_G12C RET 48 36 Female 0.64 -0.59 1.50 192.17 1.03 1072 45 33 3 TRUE 0.73
colorectal cancer KRAS_G12C RET 33 29 Male 0.56 -0.99 1.55 18.66 1.06 1304 32 28 1 TRUE 0.43
non-small cell lung cancer KRAS_G12C RET 292 55 Female 0.70 0.13 1.28 1291.58 1.00 1882 277 40 15 TRUE 1.76
non-small cell lung cancer KRAS_G12C RET 179 38 Male 0.35 -0.64 0.97 1085.52 1.00 1398 175 34 4 TRUE 0.40
colorectal cancer KRAS_G12C RET 81 65 Sex:overall 0.59 -1.01 1.76 192.60 1.04 2376 77 61 4 TRUE 0.44
non-small cell lung cancer KRAS_G12C RET 471 93 Sex:overall 0.52 -0.44 1.29 1337.50 1.00 3280 452 74 19 TRUE 0.52
colorectal cancer KRAS_G12C KDM5A 41 31 Female -5.06 -12.09 -0.59 1381.44 1.00 980 41 31 0 FALSE 1.03
colorectal cancer KRAS_G12C KDM5A 29 65 Male -5.10 -11.97 -0.64 1422.20 1.00 1155 29 65 0 FALSE 1.02
non-small cell lung cancer KRAS_G12C KDM5A 284 37 Female 0.64 -0.05 1.36 1151.97 1.00 1837 274 27 10 FALSE 1.09
non-small cell lung cancer KRAS_G12C KDM5A 172 36 Male 0.29 -0.68 1.02 1377.35 1.00 1349 168 32 4 FALSE 0.31
colorectal cancer KRAS_G12C KDM5A 70 96 Sex:overall -4.99 -11.80 -0.61 1411.73 1.00 2135 70 96 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C KDM5A 456 73 Sex:overall 0.45 -0.62 1.43 1394.97 1.00 3186 442 59 14 FALSE 0.37
colorectal cancer KRAS_G12C PIK3C2G 38 30 Female -1.73 -5.08 0.46 1255.39 1.00 953 38 30 0 FALSE 0.63
colorectal cancer KRAS_G12C PIK3C2G 28 57 Male -1.29 -4.10 0.65 1220.59 1.00 1128 27 56 1 FALSE 0.53
non-small cell lung cancer KRAS_G12C PIK3C2G 283 70 Female -0.37 -0.89 0.44 2.14 1.76 1795 273 60 10 FALSE 0.40
non-small cell lung cancer KRAS_G12C PIK3C2G 173 61 Male -0.49 -1.09 0.26 3.31 1.36 1320 169 57 4 FALSE 0.64
colorectal cancer KRAS_G12C PIK3C2G 66 87 Sex:overall -1.45 -4.39 0.74 1185.46 1.00 2081 65 86 1 FALSE 0.57
non-small cell lung cancer KRAS_G12C PIK3C2G 456 131 Sex:overall -0.43 -0.94 0.48 3.10 1.38 3115 442 117 14 FALSE 0.44
non-small cell lung cancer KRAS_G12C TSHR 284 47 Female 0.40 -0.29 1.04 1309.43 1.00 1827 276 39 8 TRUE 0.62
non-small cell lung cancer KRAS_G12C TSHR 172 22 Male 0.55 -0.23 1.35 1281.03 1.00 1361 167 17 5 TRUE 0.72
non-small cell lung cancer KRAS_G12C TSHR 456 69 Sex:overall 0.45 -0.53 1.44 1370.98 1.00 3188 443 56 13 TRUE 0.45
colorectal cancer KRAS_G12C CREBBP 41 81 Female -0.62 -2.19 0.65 1050.93 1.00 950 38 78 3 TRUE 0.42
colorectal cancer KRAS_G12C CREBBP 29 107 Male -1.49 -4.99 0.22 918.79 1.00 1124 29 107 0 TRUE 0.56
non-small cell lung cancer KRAS_G12C CREBBP 283 82 Female -0.25 -0.93 0.33 1079.98 1.00 1796 275 74 8 TRUE 0.37
non-small cell lung cancer KRAS_G12C CREBBP 172 60 Male -0.17 -0.80 0.47 1346.71 1.00 1329 165 53 7 TRUE 0.21
colorectal cancer KRAS_G12C CREBBP 70 188 Sex:overall -1.01 -3.29 0.72 1013.28 1.00 2074 67 185 3 TRUE 0.51
non-small cell lung cancer KRAS_G12C CREBBP 455 142 Sex:overall -0.20 -0.91 0.49 1416.43 1.00 3125 440 127 15 TRUE 0.21
non-small cell lung cancer KRAS_G12C BRIP1 283 36 Female 0.09 -0.62 0.87 152.53 1.03 1835 277 30 6 TRUE 0.09
non-small cell lung cancer KRAS_G12C BRIP1 172 34 Male 0.06 -0.75 0.81 251.26 1.02 1348 168 30 4 TRUE 0.06
non-small cell lung cancer KRAS_G12C BRIP1 455 70 Sex:overall 0.08 -0.77 0.94 336.28 1.02 3183 445 60 10 TRUE 0.06
colorectal cancer KRAS_G12C AXIN2 41 48 Female -5.24 -12.06 -0.98 224.23 1.01 970 41 48 0 TRUE 1.02
colorectal cancer KRAS_G12C AXIN2 29 67 Male -5.21 -12.05 -0.87 223.84 1.01 1146 29 67 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C AXIN2 283 31 Female 0.30 -0.51 1.07 908.80 1.00 1839 277 25 6 TRUE 0.36
non-small cell lung cancer KRAS_G12C AXIN2 172 31 Male 0.24 -0.63 1.03 1131.88 1.00 1351 168 27 4 TRUE 0.24
colorectal cancer KRAS_G12C AXIN2 70 115 Sex:overall -5.15 -11.96 -0.85 222.63 1.01 2116 70 115 0 TRUE 1.01
non-small cell lung cancer KRAS_G12C AXIN2 455 62 Sex:overall 0.26 -0.70 1.19 1142.76 1.00 3190 445 52 10 TRUE 0.23
colorectal cancer KRAS_G12C DOT1L 41 30 Female -1.78 -5.20 0.41 1042.70 1.00 981 41 30 0 FALSE 0.64
colorectal cancer KRAS_G12C DOT1L 29 54 Male -1.27 -4.19 0.70 1011.94 1.00 1162 28 53 1 FALSE 0.53
non-small cell lung cancer KRAS_G12C DOT1L 284 46 Female 0.38 -0.35 1.11 1416.39 1.00 1828 274 36 10 FALSE 0.51
non-small cell lung cancer KRAS_G12C DOT1L 172 61 Male -0.15 -1.07 0.59 1499.49 1.00 1324 167 56 5 FALSE 0.15
colorectal cancer KRAS_G12C DOT1L 70 84 Sex:overall -1.50 -4.59 0.71 996.15 1.00 2143 69 83 1 FALSE 0.57
non-small cell lung cancer KRAS_G12C DOT1L 456 107 Sex:overall 0.10 -1.29 1.41 1375.07 1.00 3152 441 92 15 FALSE 0.05
colorectal cancer KRAS_G12C PTPRS 38 107 Female -1.24 -2.83 -0.02 1375.70 1.00 892 37 106 1 FALSE 1.04
colorectal cancer KRAS_G12C PTPRS 28 147 Male -1.08 -2.51 0.05 1206.23 1.00 1059 26 145 2 FALSE 0.97
non-small cell lung cancer KRAS_G12C PTPRS 284 43 Female 0.68 0.07 1.26 591.59 1.00 1821 273 32 11 FALSE 1.58
non-small cell lung cancer KRAS_G12C PTPRS 175 37 Male 0.58 -0.11 1.19 496.36 1.01 1343 169 31 6 FALSE 1.06
colorectal cancer KRAS_G12C PTPRS 66 254 Sex:overall -1.15 -2.73 0.12 1384.85 1.00 1951 63 251 3 FALSE 0.91
non-small cell lung cancer KRAS_G12C PTPRS 459 80 Sex:overall 0.62 -0.17 1.36 822.53 1.00 3164 442 63 17 FALSE 0.78
colorectal cancer KRAS_G12C SMARCA4 41 77 Female -2.40 -5.59 -0.41 248.98 1.02 946 41 77 0 FALSE 1.15
colorectal cancer KRAS_G12C SMARCA4 29 92 Male -2.04 -4.84 -0.18 251.44 1.02 1137 28 91 1 FALSE 1.12
non-small cell lung cancer KRAS_G12C SMARCA4 286 163 Female 0.32 -0.06 0.72 981.34 1.00 1743 256 133 30 FALSE 0.96
non-small cell lung cancer KRAS_G12C SMARCA4 173 150 Male 0.03 -0.51 0.50 1000.61 1.00 1249 158 135 15 FALSE 0.04
colorectal cancer KRAS_G12C SMARCA4 70 169 Sex:overall -2.21 -5.26 -0.20 232.82 1.02 2083 69 168 1 FALSE 1.13
non-small cell lung cancer KRAS_G12C SMARCA4 459 313 Sex:overall 0.17 -0.63 0.86 1337.17 1.00 2992 414 268 45 FALSE 0.19
colorectal cancer KRAS_G12C PTPRT 42 71 Female -0.03 -1.19 0.96 1405.58 1.00 945 39 68 3 FALSE 0.02
colorectal cancer KRAS_G12C PTPRT 30 114 Male -0.04 -1.13 0.89 1347.93 1.00 1108 27 111 3 FALSE 0.03
non-small cell lung cancer KRAS_G12C PTPRT 285 205 Female 0.18 -0.18 0.56 777.26 1.01 1728 251 171 34 FALSE 0.49
non-small cell lung cancer KRAS_G12C PTPRT 172 146 Male -0.07 -0.66 0.35 456.91 1.00 1269 160 134 12 FALSE 0.10
colorectal cancer KRAS_G12C PTPRT 72 185 Sex:overall -0.05 -1.40 1.13 1279.09 1.00 2053 66 179 6 FALSE 0.03
non-small cell lung cancer KRAS_G12C PTPRT 457 351 Sex:overall 0.06 -0.60 0.60 1313.27 1.00 2997 411 305 46 FALSE 0.06
colorectal cancer KRAS_G12C HGF 41 14 Female -0.78 -4.52 1.29 1313.54 1.00 996 41 14 0 FALSE 0.20
colorectal cancer KRAS_G12C HGF 29 42 Male 0.19 -1.76 1.68 1448.72 1.00 1168 27 40 2 FALSE 0.08
non-small cell lung cancer KRAS_G12C HGF 283 108 Female 0.05 -0.47 0.50 1088.33 1.00 1776 270 95 13 FALSE 0.08
non-small cell lung cancer KRAS_G12C HGF 174 83 Male 0.28 -0.23 0.82 1342.87 1.00 1313 160 69 14 FALSE 0.53
colorectal cancer KRAS_G12C HGF 70 56 Sex:overall -0.29 -3.30 1.79 1306.56 1.00 2164 68 54 2 FALSE 0.09
non-small cell lung cancer KRAS_G12C HGF 457 191 Sex:overall 0.16 -0.49 0.86 1574.79 1.00 3089 430 164 27 FALSE 0.20
colorectal cancer KRAS_G12C BLM 41 26 Female -5.04 -12.58 -0.55 955.48 1.00 985 41 26 0 TRUE 0.98
colorectal cancer KRAS_G12C BLM 29 44 Male -5.04 -12.80 -0.58 1099.17 1.00 1167 29 44 0 TRUE 0.99
colorectal cancer KRAS_G12C BLM 70 70 Sex:overall -4.97 -12.10 -0.54 952.17 1.00 2152 70 70 0 TRUE 1.00
colorectal cancer KRAS_G12C PIK3CA 48 244 Female -0.34 -1.08 0.31 1045.70 1.00 892 40 236 8 TRUE 0.47
colorectal cancer KRAS_G12C PIK3CA 33 267 Male -0.51 -1.38 0.26 1155.33 1.00 1100 29 263 4 TRUE 0.65
non-small cell lung cancer KRAS_G12C PIK3CA 293 141 Female -0.05 -0.52 0.40 1134.36 1.00 1807 273 121 20 TRUE 0.07
non-small cell lung cancer KRAS_G12C PIK3CA 179 101 Male -0.19 -0.75 0.29 1108.81 1.00 1338 171 93 8 TRUE 0.33
colorectal cancer KRAS_G12C PIK3CA 81 511 Sex:overall -0.42 -1.47 0.54 1292.63 1.00 1992 69 499 12 TRUE 0.38
non-small cell lung cancer KRAS_G12C PIK3CA 472 242 Sex:overall -0.12 -0.74 0.44 1390.15 1.00 3145 444 214 28 TRUE 0.15
non-small cell lung cancer KRAS_G12C GATA3 283 40 Female 0.84 0.21 1.43 1443.08 1.00 1838 272 29 11 FALSE 2.10
non-small cell lung cancer KRAS_G12C GATA3 172 26 Male 0.77 0.01 1.42 1433.86 1.00 1358 167 21 5 FALSE 1.52
non-small cell lung cancer KRAS_G12C GATA3 455 66 Sex:overall 0.80 0.01 1.50 1446.41 1.00 3196 439 50 16 FALSE 1.45
colorectal cancer KRAS_G12C ESR1 41 26 Female -0.39 -2.34 1.10 1385.11 1.00 986 40 25 1 TRUE 0.18
colorectal cancer KRAS_G12C ESR1 29 46 Male -0.42 -2.39 1.08 1449.00 1.00 1161 28 45 1 TRUE 0.19
non-small cell lung cancer KRAS_G12C ESR1 283 30 Female -0.24 -1.41 0.77 874.47 1.00 1842 278 25 5 TRUE 0.17
non-small cell lung cancer KRAS_G12C ESR1 172 26 Male -1.31 -5.17 0.31 1027.92 1.00 1352 172 26 0 TRUE 0.44
colorectal cancer KRAS_G12C ESR1 70 72 Sex:overall -0.38 -2.64 1.39 1203.82 1.00 2147 68 70 2 TRUE 0.15
non-small cell lung cancer KRAS_G12C ESR1 455 56 Sex:overall -0.76 -3.31 0.74 1431.20 1.00 3194 450 51 5 TRUE 0.36
colorectal cancer KRAS_G12C ALK 48 55 Female -0.96 -2.82 0.42 940.66 1.00 1055 47 54 1 TRUE 0.55
colorectal cancer KRAS_G12C ALK 33 60 Male -0.91 -2.89 0.59 921.54 1.00 1282 32 59 1 TRUE 0.50
non-small cell lung cancer KRAS_G12C ALK 292 90 Female 0.54 0.07 0.99 888.79 1.00 1856 272 70 20 TRUE 1.77
non-small cell lung cancer KRAS_G12C ALK 179 79 Male 0.40 -0.17 0.88 1391.41 1.00 1367 168 68 11 TRUE 0.91
colorectal cancer KRAS_G12C ALK 81 115 Sex:overall -0.92 -2.95 0.68 900.50 1.00 2337 79 113 2 TRUE 0.48
non-small cell lung cancer KRAS_G12C ALK 471 169 Sex:overall 0.47 -0.19 1.10 1460.31 1.00 3223 440 138 31 TRUE 0.84
colorectal cancer KRAS_G12C RNF43 41 140 Female -1.81 -3.78 -0.38 945.00 1.00 907 40 139 1 TRUE 1.50
colorectal cancer KRAS_G12C RNF43 29 127 Male -1.68 -3.72 -0.20 830.26 1.00 1110 28 126 1 TRUE 1.24
colorectal cancer KRAS_G12C RNF43 70 267 Sex:overall -1.72 -3.80 -0.03 949.78 1.00 2017 68 265 2 TRUE 1.20
non-small cell lung cancer KRAS_G12C U2AF1 283 52 Female 0.48 -0.16 1.07 1230.87 1.00 1822 273 42 10 FALSE 0.89
non-small cell lung cancer KRAS_G12C U2AF1 172 26 Male 0.52 -0.23 1.24 1593.18 1.00 1359 167 21 5 FALSE 0.80
non-small cell lung cancer KRAS_G12C U2AF1 455 78 Sex:overall 0.50 -0.33 1.30 1375.96 1.00 3181 440 63 15 FALSE 0.64
colorectal cancer KRAS_G12C LATS1 38 19 Female -4.72 -11.35 -0.12 628.63 1.00 960 38 19 0 FALSE 0.93
colorectal cancer KRAS_G12C LATS1 28 36 Male -4.69 -11.37 -0.21 558.80 1.00 1144 28 36 0 FALSE 0.97
non-small cell lung cancer KRAS_G12C LATS1 283 41 Female -0.84 -2.03 0.20 961.10 1.00 1816 279 37 4 FALSE 0.84
non-small cell lung cancer KRAS_G12C LATS1 172 27 Male -1.36 -4.09 -0.06 1217.87 1.00 1346 172 27 0 FALSE 0.66
colorectal cancer KRAS_G12C LATS1 66 55 Sex:overall -4.61 -11.39 -0.09 579.35 1.00 2104 66 55 0 FALSE 0.97
non-small cell lung cancer KRAS_G12C LATS1 455 68 Sex:overall -1.07 -3.08 0.30 1413.37 1.01 3162 451 64 4 FALSE 0.74
colorectal cancer KRAS_G12C LATS2 38 26 Female -0.97 -3.71 0.86 1035.00 1.00 956 37 25 1 FALSE 0.39
colorectal cancer KRAS_G12C LATS2 28 44 Male -1.40 -4.95 0.63 923.36 1.00 1131 28 44 0 FALSE 0.48
non-small cell lung cancer KRAS_G12C LATS2 284 30 Female 0.32 -0.53 1.17 1360.28 1.00 1830 277 23 7 FALSE 0.34
non-small cell lung cancer KRAS_G12C LATS2 172 31 Male -0.12 -1.36 0.79 1380.42 1.00 1345 170 29 2 FALSE 0.08
colorectal cancer KRAS_G12C LATS2 66 70 Sex:overall -1.15 -3.94 0.84 1172.95 1.00 2087 65 69 1 FALSE 0.42
non-small cell lung cancer KRAS_G12C LATS2 456 61 Sex:overall 0.10 -1.08 1.21 1393.70 1.00 3175 447 52 9 FALSE 0.06
colorectal cancer KRAS_G12C PTEN 48 80 Female -0.83 -2.29 0.35 1211.91 1.00 1046 46 78 2 TRUE 0.65
colorectal cancer KRAS_G12C PTEN 33 105 Male -0.99 -2.67 0.26 1127.28 1.00 1252 32 104 1 TRUE 0.72
non-small cell lung cancer KRAS_G12C PTEN 292 60 Female -0.62 -1.44 0.08 1524.09 1.00 1867 287 55 5 TRUE 0.92
non-small cell lung cancer KRAS_G12C PTEN 179 76 Male -0.62 -1.46 0.14 1502.84 1.00 1364 174 71 5 TRUE 0.90
colorectal cancer KRAS_G12C PTEN 81 185 Sex:overall -0.91 -2.57 0.44 1193.74 1.00 2298 78 182 3 TRUE 0.61
non-small cell lung cancer KRAS_G12C PTEN 471 136 Sex:overall -0.59 -1.71 0.44 1342.81 1.00 3231 461 126 10 TRUE 0.56
colorectal cancer KRAS_G12C BCOR 41 59 Female -2.11 -5.55 -0.01 1189.98 1.00 963 41 59 0 FALSE 0.85
colorectal cancer KRAS_G12C BCOR 29 53 Male -1.54 -4.51 0.49 1057.47 1.00 1157 28 52 1 FALSE 0.66
non-small cell lung cancer KRAS_G12C BCOR 286 103 Female 0.20 -0.38 0.69 1468.30 1.00 1783 270 87 16 FALSE 0.33
non-small cell lung cancer KRAS_G12C BCOR 173 31 Male 0.28 -0.58 1.10 1486.95 1.00 1353 168 26 5 FALSE 0.29
colorectal cancer KRAS_G12C BCOR 70 112 Sex:overall -1.82 -4.96 0.32 1189.70 1.00 2120 69 111 1 FALSE 0.75
non-small cell lung cancer KRAS_G12C BCOR 459 134 Sex:overall 0.25 -0.96 1.57 1408.28 1.00 3136 438 113 21 FALSE 0.17
colorectal cancer KRAS_G12C CTNNB1 48 74 Female 0.11 -0.95 0.99 1178.35 1.00 1036 44 70 4 TRUE 0.08
colorectal cancer KRAS_G12C CTNNB1 33 89 Male -0.01 -1.24 0.95 1306.64 1.00 1249 31 87 2 TRUE 0.01
non-small cell lung cancer KRAS_G12C CTNNB1 293 74 Female -0.56 -1.34 0.09 974.74 1.00 1853 288 69 5 TRUE 0.89
non-small cell lung cancer KRAS_G12C CTNNB1 179 47 Male -0.41 -1.18 0.32 1418.02 1.00 1388 174 42 5 TRUE 0.53
colorectal cancer KRAS_G12C CTNNB1 81 163 Sex:overall 0.06 -1.19 1.17 1112.75 1.00 2285 75 157 6 TRUE 0.04
non-small cell lung cancer KRAS_G12C CTNNB1 472 121 Sex:overall -0.47 -1.35 0.35 1222.39 1.00 3241 462 111 10 TRUE 0.51
colorectal cancer KRAS_G12C ARID1A 41 149 Female -1.02 -2.20 0.01 1307.58 1.00 915 38 146 3 TRUE 1.12
colorectal cancer KRAS_G12C ARID1A 29 166 Male -1.20 -2.58 -0.11 1251.77 1.00 1083 28 165 1 TRUE 1.24
non-small cell lung cancer KRAS_G12C ARID1A 284 132 Female 0.21 -0.23 0.62 1550.58 1.00 1762 263 111 21 TRUE 0.48
non-small cell lung cancer KRAS_G12C ARID1A 177 152 Male 0.24 -0.22 0.67 1574.87 1.00 1257 156 131 21 TRUE 0.58
colorectal cancer KRAS_G12C ARID1A 70 315 Sex:overall -1.11 -2.51 0.14 1267.08 1.00 1998 66 311 4 TRUE 1.01
non-small cell lung cancer KRAS_G12C ARID1A 461 284 Sex:overall 0.24 -0.60 1.00 1450.98 1.00 3019 419 242 42 TRUE 0.23
colorectal cancer KRAS_G12C PIK3R1 41 44 Female -0.60 -2.46 0.82 1154.65 1.00 971 39 42 2 TRUE 0.33
colorectal cancer KRAS_G12C PIK3R1 29 72 Male -1.40 -4.92 0.39 1290.37 1.00 1147 29 72 0 TRUE 0.56
non-small cell lung cancer KRAS_G12C PIK3R1 283 30 Female 0.28 -0.62 1.02 1412.39 1.00 1839 279 26 4 TRUE 0.30
non-small cell lung cancer KRAS_G12C PIK3R1 173 25 Male 0.56 -0.29 1.37 1236.78 1.00 1359 167 19 6 TRUE 0.71
colorectal cancer KRAS_G12C PIK3R1 70 116 Sex:overall -0.98 -3.51 0.78 1412.97 1.00 2118 68 114 2 TRUE 0.41
non-small cell lung cancer KRAS_G12C PIK3R1 456 55 Sex:overall 0.40 -0.53 1.29 1437.93 1.00 3198 446 45 10 TRUE 0.35
colorectal cancer KRAS_G12C IKZF1 41 42 Female -0.62 -2.52 0.81 1311.65 1.00 972 40 41 1 TRUE 0.34
colorectal cancer KRAS_G12C IKZF1 29 44 Male -0.54 -2.49 0.93 1462.88 1.00 1163 28 43 1 TRUE 0.26
non-small cell lung cancer KRAS_G12C IKZF1 283 48 Female 0.18 -0.38 0.80 68.25 1.04 1824 276 41 7 TRUE 0.26
non-small cell lung cancer KRAS_G12C IKZF1 172 34 Male 0.27 -0.33 0.97 23.17 1.08 1351 166 28 6 TRUE 0.35
colorectal cancer KRAS_G12C IKZF1 70 86 Sex:overall -0.58 -2.63 0.94 1375.09 1.00 2135 68 84 2 TRUE 0.27
non-small cell lung cancer KRAS_G12C IKZF1 455 82 Sex:overall 0.22 -0.49 0.99 47.70 1.04 3175 442 69 13 TRUE 0.26
colorectal cancer KRAS_G12C TERT 41 40 Female 0.55 -0.77 1.64 721.77 1.00 976 37 36 4 TRUE 0.44
colorectal cancer KRAS_G12C TERT 29 58 Male -0.74 -4.81 1.03 903.02 1.00 1155 29 58 0 TRUE 0.20
non-small cell lung cancer KRAS_G12C TERT 285 87 Female 0.70 0.25 1.16 1283.80 1.00 1801 263 65 22 TRUE 2.59
non-small cell lung cancer KRAS_G12C TERT 173 79 Male 0.53 0.00 1.01 1413.46 1.00 1315 161 67 12 TRUE 1.36
colorectal cancer KRAS_G12C TERT 70 98 Sex:overall -0.08 -2.73 1.75 1111.93 1.00 2131 66 94 4 TRUE 0.02
non-small cell lung cancer KRAS_G12C TERT 458 166 Sex:overall 0.61 -0.13 1.34 1541.36 1.00 3116 424 132 34 TRUE 1.03
colorectal cancer KRAS_G12C FAT1 41 97 Female -5.61 -12.21 -1.58 1242.38 1.00 938 41 97 0 FALSE 1.38
colorectal cancer KRAS_G12C FAT1 29 130 Male -5.61 -12.40 -1.60 1407.34 1.00 1125 29 130 0 FALSE 1.39
non-small cell lung cancer KRAS_G12C FAT1 287 155 Female 0.60 0.18 0.99 1369.79 1.00 1753 252 120 35 FALSE 2.37
non-small cell lung cancer KRAS_G12C FAT1 172 150 Male -0.13 -0.75 0.41 1513.89 1.00 1260 159 137 13 FALSE 0.18
colorectal cancer KRAS_G12C FAT1 70 227 Sex:overall -5.51 -11.96 -1.59 1325.09 1.00 2063 70 227 0 FALSE 1.40
non-small cell lung cancer KRAS_G12C FAT1 459 305 Sex:overall 0.22 -0.99 1.29 1497.60 1.00 3013 411 257 48 FALSE 0.15
colorectal cancer KRAS_G12C FGFR4 41 19 Female -4.82 -11.90 -0.21 777.26 1.01 993 41 19 0 TRUE 0.94
colorectal cancer KRAS_G12C FGFR4 29 34 Male -4.80 -12.03 -0.10 730.15 1.00 1173 29 34 0 TRUE 0.92
colorectal cancer KRAS_G12C FGFR4 70 53 Sex:overall -4.72 -11.64 -0.20 744.07 1.00 2166 70 53 0 TRUE 0.92
colorectal cancer KRAS_G12C CIC 41 58 Female -1.07 -3.05 0.36 1123.53 1.00 965 40 57 1 TRUE 0.67
colorectal cancer KRAS_G12C CIC 29 79 Male -1.01 -3.06 0.42 1234.82 1.00 1143 28 78 1 TRUE 0.60
non-small cell lung cancer KRAS_G12C CIC 284 43 Female 0.20 -0.52 0.88 1537.91 1.00 1831 276 35 8 TRUE 0.24
non-small cell lung cancer KRAS_G12C CIC 175 49 Male 0.03 -0.80 0.71 1386.78 1.00 1340 170 44 5 TRUE 0.02
colorectal cancer KRAS_G12C CIC 70 137 Sex:overall -1.02 -3.13 0.55 1145.16 1.00 2108 68 135 2 TRUE 0.57
non-small cell lung cancer KRAS_G12C CIC 459 92 Sex:overall 0.12 -0.82 1.05 1381.43 1.00 3171 446 79 13 TRUE 0.10
colorectal cancer KRAS_G12C KDM6A 41 31 Female -4.72 -11.81 -0.42 399.56 1.01 981 41 31 0 FALSE 0.88
colorectal cancer KRAS_G12C KDM6A 29 31 Male -4.68 -11.36 -0.27 420.08 1.01 1175 29 31 0 FALSE 0.88
non-small cell lung cancer KRAS_G12C KDM6A 283 28 Female -0.35 -1.45 0.59 1345.42 1.00 1841 280 25 3 FALSE 0.31
non-small cell lung cancer KRAS_G12C KDM6A 172 33 Male -0.32 -1.38 0.60 1210.41 1.00 1350 169 30 3 FALSE 0.29
colorectal cancer KRAS_G12C KDM6A 70 62 Sex:overall -4.64 -11.23 -0.25 397.90 1.01 2156 70 62 0 FALSE 0.88
non-small cell lung cancer KRAS_G12C KDM6A 455 61 Sex:overall -0.34 -1.52 0.69 1463.01 1.00 3191 449 55 6 FALSE 0.25
colorectal cancer KRAS_G12C NCOR1 41 54 Female -5.42 -12.43 -1.02 1325.41 1.00 961 41 54 0 FALSE 1.14
colorectal cancer KRAS_G12C NCOR1 29 81 Male -5.39 -12.35 -1.18 1175.24 1.00 1144 29 81 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C NCOR1 285 53 Female 0.24 -0.39 0.88 1272.17 1.00 1826 275 43 10 FALSE 0.35
non-small cell lung cancer KRAS_G12C NCOR1 172 51 Male 0.06 -0.71 0.69 1340.16 1.00 1335 167 46 5 FALSE 0.06
colorectal cancer KRAS_G12C NCOR1 70 135 Sex:overall -5.34 -12.32 -1.10 1280.71 1.00 2105 70 135 0 FALSE 1.16
non-small cell lung cancer KRAS_G12C NCOR1 457 104 Sex:overall 0.14 -0.74 0.95 1324.62 1.00 3161 442 89 15 FALSE 0.12
colorectal cancer KRAS_G12C POLE 41 59 Female -5.42 -12.05 -1.07 1015.42 1.00 960 41 59 0 TRUE 1.22
colorectal cancer KRAS_G12C POLE 29 82 Male -5.34 -11.97 -0.95 1150.80 1.01 1141 29 82 0 TRUE 1.21
non-small cell lung cancer KRAS_G12C POLE 283 67 Female 0.66 0.15 1.15 1316.09 1.00 1818 268 52 15 TRUE 2.05
non-small cell lung cancer KRAS_G12C POLE 173 69 Male 0.72 0.20 1.23 1190.62 1.00 1325 159 55 14 TRUE 2.20
colorectal cancer KRAS_G12C POLE 70 141 Sex:overall -5.29 -11.60 -0.95 1050.42 1.00 2101 70 141 0 TRUE 1.23
non-small cell lung cancer KRAS_G12C POLE 456 136 Sex:overall 0.66 -0.09 1.33 1199.27 1.00 3143 427 107 29 TRUE 0.92
non-small cell lung cancer KRAS_G12C CUL3 284 34 Female 0.42 -0.32 1.14 1445.17 1.00 1840 278 28 6 FALSE 0.60
non-small cell lung cancer KRAS_G12C CUL3 172 43 Male 0.66 -0.03 1.36 1422.02 1.00 1347 163 34 9 FALSE 1.23
non-small cell lung cancer KRAS_G12C CUL3 456 77 Sex:overall 0.54 -0.50 1.52 1200.10 1.00 3187 441 62 15 FALSE 0.52
colorectal cancer KRAS_G12C ABL1 48 34 Female -4.98 -12.16 -0.68 228.97 1.02 1072 48 34 0 TRUE 1.00
colorectal cancer KRAS_G12C ABL1 33 39 Male -4.95 -12.13 -0.66 234.16 1.01 1298 33 39 0 TRUE 0.98
colorectal cancer KRAS_G12C ABL1 81 73 Sex:overall -4.88 -12.09 -0.63 232.80 1.01 2370 81 73 0 TRUE 0.98
colorectal cancer KRAS_G12C FOXP1 41 24 Female -1.52 -5.06 0.54 1360.36 1.00 986 41 24 0 FALSE 0.51
colorectal cancer KRAS_G12C FOXP1 29 46 Male -1.03 -3.73 0.92 1320.77 1.00 1164 28 45 1 FALSE 0.41
colorectal cancer KRAS_G12C FOXP1 70 70 Sex:overall -1.26 -4.21 0.86 1384.01 1.00 2150 69 69 1 FALSE 0.46
colorectal cancer KRAS_G12C NOTCH2 38 30 Female -6.21 -16.14 -0.80 16.02 1.12 954 38 30 0 TRUE 0.80
colorectal cancer KRAS_G12C NOTCH2 28 43 Male -6.18 -15.86 -0.68 14.19 1.13 1135 28 43 0 TRUE 0.80
non-small cell lung cancer KRAS_G12C NOTCH2 283 62 Female -0.08 -0.73 0.56 1163.28 1.00 1805 274 53 9 TRUE 0.09
non-small cell lung cancer KRAS_G12C NOTCH2 172 53 Male -0.23 -1.04 0.45 1208.26 1.00 1329 168 49 4 TRUE 0.26
colorectal cancer KRAS_G12C NOTCH2 66 73 Sex:overall -6.13 -16.07 -0.68 14.56 1.13 2089 66 73 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C NOTCH2 455 115 Sex:overall -0.15 -1.01 0.60 1476.38 1.00 3134 442 102 13 TRUE 0.13
non-small cell lung cancer KRAS_G12C DDR2 283 49 Female 0.28 -0.36 0.86 1168.50 1.00 1824 274 40 9 TRUE 0.43
non-small cell lung cancer KRAS_G12C DDR2 172 49 Male 0.19 -0.57 0.81 1409.61 1.00 1335 166 43 6 TRUE 0.23
non-small cell lung cancer KRAS_G12C DDR2 455 98 Sex:overall 0.24 -0.63 1.03 1420.62 1.00 3159 440 83 15 TRUE 0.25
colorectal cancer KRAS_G12C TGFBR2 41 53 Female -1.66 -4.51 0.22 760.54 1.00 960 40 52 1 TRUE 0.79
colorectal cancer KRAS_G12C TGFBR2 29 61 Male -1.99 -5.43 0.08 989.50 1.00 1147 29 61 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C TGFBR2 284 35 Female 0.75 0.06 1.42 1063.29 1.00 1842 274 25 10 TRUE 1.49
non-small cell lung cancer KRAS_G12C TGFBR2 172 21 Male 0.42 -0.84 1.22 1073.37 1.01 1359 170 19 2 TRUE 0.39
colorectal cancer KRAS_G12C TGFBR2 70 114 Sex:overall -1.81 -4.84 0.29 772.21 1.00 2107 69 113 1 TRUE 0.79
non-small cell lung cancer KRAS_G12C TGFBR2 456 56 Sex:overall 0.58 -0.65 1.48 1292.01 1.00 3201 444 44 12 TRUE 0.56
colorectal cancer KRAS_G12C SMO 48 32 Female -1.22 -4.14 0.68 1058.23 1.00 1074 47 31 1 TRUE 0.51
colorectal cancer KRAS_G12C SMO 33 39 Male -1.56 -4.78 0.46 841.55 1.00 1297 33 39 0 TRUE 0.56
non-small cell lung cancer KRAS_G12C SMO 292 39 Female 0.16 -0.63 0.85 1263.31 1.00 1890 287 34 5 TRUE 0.17
non-small cell lung cancer KRAS_G12C SMO 179 36 Male 0.39 -0.34 1.13 1375.33 1.00 1400 172 29 7 TRUE 0.54
colorectal cancer KRAS_G12C SMO 81 71 Sex:overall -1.36 -4.45 0.79 846.42 1.00 2371 80 70 1 TRUE 0.53
non-small cell lung cancer KRAS_G12C SMO 471 75 Sex:overall 0.27 -0.65 1.16 1297.97 1.00 3290 459 63 12 TRUE 0.25
colorectal cancer KRAS_G12C RPS6KA4 38 26 Female -1.38 -4.94 0.63 1063.45 1.00 956 38 26 0 FALSE 0.44
colorectal cancer KRAS_G12C RPS6KA4 28 37 Male -0.98 -3.87 0.93 1148.59 1.00 1138 27 36 1 FALSE 0.37
colorectal cancer KRAS_G12C RPS6KA4 66 63 Sex:overall -1.14 -4.27 0.86 1048.39 1.00 2094 65 62 1 FALSE 0.41
colorectal cancer KRAS_G12C KMT2A 41 69 Female -1.14 -3.22 0.23 1110.50 1.00 959 40 68 1 FALSE 0.74
colorectal cancer KRAS_G12C KMT2A 29 79 Male -1.10 -3.08 0.33 1225.84 1.00 1143 28 78 1 FALSE 0.68
non-small cell lung cancer KRAS_G12C KMT2A 283 64 Female 0.11 -0.48 0.68 1413.97 1.00 1814 274 55 9 FALSE 0.15
non-small cell lung cancer KRAS_G12C KMT2A 172 50 Male 0.16 -0.46 0.74 1456.55 1.00 1337 165 43 7 FALSE 0.21
colorectal cancer KRAS_G12C KMT2A 70 148 Sex:overall -1.10 -3.13 0.49 1241.55 1.00 2102 68 146 2 FALSE 0.62
non-small cell lung cancer KRAS_G12C KMT2A 455 114 Sex:overall 0.12 -0.62 0.82 1299.71 1.00 3151 439 98 16 FALSE 0.13
colorectal cancer KRAS_G12C JAK3 48 33 Female -0.16 -2.06 1.22 1452.95 1.00 1076 46 31 2 TRUE 0.07
colorectal cancer KRAS_G12C JAK3 33 30 Male -0.73 -4.05 1.10 1226.47 1.00 1302 33 30 0 TRUE 0.24
non-small cell lung cancer KRAS_G12C JAK3 292 50 Female 0.43 -0.19 1.00 1436.83 1.00 1883 282 40 10 TRUE 0.80
non-small cell lung cancer KRAS_G12C JAK3 180 33 Male 0.38 -0.37 0.99 1453.78 1.00 1401 175 28 5 TRUE 0.55
colorectal cancer KRAS_G12C JAK3 81 63 Sex:overall -0.43 -2.72 1.27 1528.97 1.00 2378 79 61 2 TRUE 0.16
non-small cell lung cancer KRAS_G12C JAK3 472 83 Sex:overall 0.42 -0.31 1.16 1394.33 1.00 3284 457 68 15 TRUE 0.55
non-small cell lung cancer KRAS_G12C PAK7 283 71 Female -0.11 -0.75 0.48 1507.14 1.00 1793 275 63 8 FALSE 0.14
non-small cell lung cancer KRAS_G12C PAK7 172 62 Male 0.00 -0.63 0.66 1310.50 1.00 1325 164 54 8 FALSE 0.01
non-small cell lung cancer KRAS_G12C PAK7 455 133 Sex:overall -0.05 -0.85 0.69 1408.51 1.00 3118 439 117 16 FALSE 0.04
non-small cell lung cancer KRAS_G12C STAG2 283 75 Female 0.24 -0.38 0.81 1473.36 1.00 1806 270 62 13 TRUE 0.36
non-small cell lung cancer KRAS_G12C STAG2 172 27 Male -0.19 -1.48 0.70 1462.86 1.00 1355 170 25 2 TRUE 0.14
non-small cell lung cancer KRAS_G12C STAG2 455 102 Sex:overall 0.03 -1.21 1.12 1420.83 1.00 3161 440 87 15 TRUE 0.01
colorectal cancer KRAS_G12C BRCA2 41 75 Female -1.16 -2.93 0.24 1083.12 1.00 950 39 73 2 TRUE 0.79
colorectal cancer KRAS_G12C BRCA2 29 115 Male -1.86 -5.09 -0.21 1083.24 1.00 1139 29 115 0 TRUE 0.76
non-small cell lung cancer KRAS_G12C BRCA2 283 72 Female 0.22 -0.35 0.75 1254.03 1.00 1814 270 59 13 TRUE 0.36
non-small cell lung cancer KRAS_G12C BRCA2 172 63 Male 0.03 -0.72 0.64 1156.42 1.00 1324 166 57 6 TRUE 0.03
colorectal cancer KRAS_G12C BRCA2 70 190 Sex:overall -1.48 -3.90 0.24 1294.25 1.00 2089 68 188 2 TRUE 0.78
non-small cell lung cancer KRAS_G12C BRCA2 455 135 Sex:overall 0.14 -0.63 0.89 1354.25 1.00 3138 436 116 19 TRUE 0.13
colorectal cancer KRAS_G12C NOTCH3 41 88 Female -5.60 -11.72 -1.53 174.76 1.03 937 41 88 0 TRUE 1.44
colorectal cancer KRAS_G12C NOTCH3 29 112 Male -5.62 -11.70 -1.56 210.55 1.03 1119 29 112 0 TRUE 1.43
non-small cell lung cancer KRAS_G12C NOTCH3 283 64 Female -0.05 -0.73 0.54 982.46 1.00 1812 275 56 8 TRUE 0.06
non-small cell lung cancer KRAS_G12C NOTCH3 172 64 Male 0.03 -0.63 0.63 1290.35 1.00 1327 164 56 8 TRUE 0.03
colorectal cancer KRAS_G12C NOTCH3 70 200 Sex:overall -5.50 -11.34 -1.39 147.19 1.03 2056 70 200 0 TRUE 1.40
non-small cell lung cancer KRAS_G12C NOTCH3 455 128 Sex:overall -0.02 -0.84 0.77 1321.60 1.00 3139 439 112 16 TRUE 0.01
colorectal cancer KRAS_G12C NOTCH4 38 45 Female -0.45 -2.12 0.80 1514.70 1.00 938 37 44 1 TRUE 0.27
colorectal cancer KRAS_G12C NOTCH4 28 77 Male -0.28 -1.79 0.98 1533.19 1.00 1111 26 75 2 TRUE 0.16
non-small cell lung cancer KRAS_G12C NOTCH4 283 82 Female -0.24 -0.90 0.32 857.54 1.00 1783 273 72 10 TRUE 0.35
non-small cell lung cancer KRAS_G12C NOTCH4 172 57 Male -0.35 -1.18 0.29 945.22 1.00 1323 168 53 4 TRUE 0.47
colorectal cancer KRAS_G12C NOTCH4 66 122 Sex:overall -0.34 -2.00 1.16 1563.59 1.00 2049 63 119 3 TRUE 0.18
non-small cell lung cancer KRAS_G12C NOTCH4 455 139 Sex:overall -0.30 -1.12 0.41 1170.31 1.00 3106 441 125 14 TRUE 0.35
colorectal cancer KRAS_G12C FGFR3 48 25 Female -4.80 -11.68 -0.53 1383.71 1.00 1079 48 25 0 TRUE 1.00
colorectal cancer KRAS_G12C FGFR3 33 35 Male -4.76 -11.37 -0.42 1232.29 1.00 1300 33 35 0 TRUE 1.01
colorectal cancer KRAS_G12C FGFR3 81 60 Sex:overall -4.69 -10.99 -0.37 1261.28 1.00 2379 81 60 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C MAP3K13 283 30 Female -0.55 -1.84 0.49 1310.52 1.00 1827 279 26 4 FALSE 0.46
non-small cell lung cancer KRAS_G12C MAP3K13 172 22 Male -1.09 -3.79 0.25 1137.05 1.00 1351 172 22 0 FALSE 0.53
non-small cell lung cancer KRAS_G12C MAP3K13 455 52 Sex:overall -0.83 -2.70 0.46 1311.75 1.00 3178 451 48 4 FALSE 0.52
colorectal cancer KRAS_G12C IGF1R 41 31 Female -5.02 -11.92 -0.57 1000.51 1.00 981 41 31 0 TRUE 1.00
colorectal cancer KRAS_G12C IGF1R 29 49 Male -5.01 -12.33 -0.40 989.47 1.00 1163 29 49 0 TRUE 0.98
non-small cell lung cancer KRAS_G12C IGF1R 283 31 Female 0.71 -0.02 1.35 490.69 1.02 1841 276 24 7 TRUE 1.36
non-small cell lung cancer KRAS_G12C IGF1R 172 23 Male 0.73 -0.02 1.47 456.11 1.02 1360 167 18 5 TRUE 1.30
colorectal cancer KRAS_G12C IGF1R 70 80 Sex:overall -4.93 -11.94 -0.52 1024.37 1.00 2144 70 80 0 TRUE 0.99
non-small cell lung cancer KRAS_G12C IGF1R 455 54 Sex:overall 0.72 -0.07 1.49 461.21 1.01 3201 443 42 12 TRUE 1.06
non-small cell lung cancer KRAS_G12C KEAP1 285 248 Female 0.62 0.29 0.93 1393.27 1.00 1674 233 196 52 FALSE 3.74
non-small cell lung cancer KRAS_G12C KEAP1 175 290 Male 0.46 0.13 0.80 1361.58 1.00 1144 131 246 44 FALSE 2.13
non-small cell lung cancer KRAS_G12C KEAP1 460 538 Sex:overall 0.54 -0.38 1.40 1531.72 1.00 2818 364 442 96 FALSE 0.67
colorectal cancer KRAS_G12C KDM5C 41 41 Female -1.80 -5.52 0.38 1289.63 1.00 979 41 41 0 FALSE 0.60
colorectal cancer KRAS_G12C KDM5C 29 28 Male -0.98 -4.05 1.04 1333.02 1.00 1179 28 27 1 FALSE 0.36
non-small cell lung cancer KRAS_G12C KDM5C 284 71 Female 0.13 -0.53 0.71 1229.75 1.00 1807 273 60 11 FALSE 0.17
non-small cell lung cancer KRAS_G12C KDM5C 172 35 Male 0.06 -0.76 0.77 1371.81 1.00 1348 168 31 4 FALSE 0.05
colorectal cancer KRAS_G12C KDM5C 70 69 Sex:overall -1.32 -4.48 1.01 1277.81 1.00 2158 69 68 1 FALSE 0.46
non-small cell lung cancer KRAS_G12C KDM5C 456 106 Sex:overall 0.10 -0.77 0.88 1557.38 1.00 3155 441 91 15 FALSE 0.08
non-small cell lung cancer KRAS_G12C CDKN2A 293 139 Female -0.36 -0.94 0.12 1355.06 1.00 1805 281 127 12 TRUE 0.73
non-small cell lung cancer KRAS_G12C CDKN2A 182 137 Male 0.03 -0.50 0.53 1214.12 1.00 1313 164 119 18 TRUE 0.04
non-small cell lung cancer KRAS_G12C CDKN2A 475 276 Sex:overall -0.16 -1.00 0.68 1635.23 1.00 3118 445 246 30 TRUE 0.14
colorectal cancer KRAS_G12C EPHB1 41 32 Female -5.06 -12.19 -0.80 370.03 1.00 978 41 32 0 FALSE 1.07
colorectal cancer KRAS_G12C EPHB1 29 50 Male -5.07 -12.24 -0.73 394.38 1.00 1157 29 50 0 FALSE 1.07
non-small cell lung cancer KRAS_G12C EPHB1 284 81 Female 0.13 -0.44 0.68 1409.68 1.00 1806 270 67 14 FALSE 0.18
non-small cell lung cancer KRAS_G12C EPHB1 172 77 Male -0.31 -1.20 0.35 1385.71 1.00 1310 167 72 5 FALSE 0.37
colorectal cancer KRAS_G12C EPHB1 70 82 Sex:overall -4.99 -12.08 -0.77 367.92 1.00 2135 70 82 0 FALSE 1.07
non-small cell lung cancer KRAS_G12C EPHB1 456 158 Sex:overall -0.07 -1.05 0.90 1428.31 1.00 3116 437 139 19 FALSE 0.06
colorectal cancer KRAS_G12C IRS2 41 29 Female -1.76 -5.29 0.38 977.41 1.00 984 41 29 0 FALSE 0.64
colorectal cancer KRAS_G12C IRS2 29 58 Male -1.36 -4.36 0.53 901.17 1.00 1153 28 57 1 FALSE 0.58
non-small cell lung cancer KRAS_G12C IRS2 283 42 Female -0.32 -1.23 0.50 1161.72 1.00 1829 278 37 5 FALSE 0.36
non-small cell lung cancer KRAS_G12C IRS2 172 42 Male -0.41 -1.39 0.39 1276.41 1.00 1340 169 39 3 FALSE 0.43
colorectal cancer KRAS_G12C IRS2 70 87 Sex:overall -1.53 -4.66 0.54 1015.84 1.00 2137 69 86 1 FALSE 0.60
non-small cell lung cancer KRAS_G12C IRS2 455 84 Sex:overall -0.38 -1.40 0.54 1335.35 1.00 3169 447 76 8 FALSE 0.35
colorectal cancer KRAS_G12C FANCA 41 31 Female -4.59 -11.14 -0.59 64.23 1.06 980 41 31 0 TRUE 0.95
colorectal cancer KRAS_G12C FANCA 29 34 Male -4.60 -11.41 -0.49 69.10 1.05 1175 29 34 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C FANCA 283 39 Female 0.06 -0.75 0.86 1288.27 1.00 1833 276 32 7 TRUE 0.06
non-small cell lung cancer KRAS_G12C FANCA 172 30 Male -0.13 -1.29 0.72 815.82 1.00 1352 170 28 2 TRUE 0.10
colorectal cancer KRAS_G12C FANCA 70 65 Sex:overall -4.49 -11.24 -0.58 59.98 1.06 2155 70 65 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C FANCA 455 69 Sex:overall -0.04 -1.21 0.91 1435.53 1.00 3185 446 60 9 TRUE 0.02
non-small cell lung cancer KRAS_G12C IL7R 284 51 Female 0.00 -0.70 0.67 1441.21 1.00 1824 276 43 8 FALSE 0.00
non-small cell lung cancer KRAS_G12C IL7R 172 40 Male -0.17 -1.13 0.53 1326.47 1.00 1346 169 37 3 FALSE 0.16
non-small cell lung cancer KRAS_G12C IL7R 456 91 Sex:overall -0.09 -1.02 0.76 1461.79 1.00 3170 445 80 11 FALSE 0.08
colorectal cancer KRAS_G12C PIK3CB 38 24 Female -1.45 -4.58 0.62 1318.15 1.00 959 38 24 0 FALSE 0.52
colorectal cancer KRAS_G12C PIK3CB 28 44 Male -1.11 -3.98 0.76 1443.37 1.00 1142 27 43 1 FALSE 0.43
colorectal cancer KRAS_G12C PIK3CB 66 68 Sex:overall -1.25 -4.12 0.85 1224.92 1.00 2101 65 67 1 FALSE 0.47
colorectal cancer KRAS_G12C ERBB3 41 52 Female -0.74 -1.87 0.60 6.88 1.14 966 40 51 1 TRUE 0.60
colorectal cancer KRAS_G12C ERBB3 29 70 Male -0.60 -1.63 0.78 4.14 1.25 1143 27 68 2 TRUE 0.43
colorectal cancer KRAS_G12C ERBB3 70 122 Sex:overall -0.67 -1.88 0.82 6.55 1.15 2109 67 119 3 TRUE 0.44
colorectal cancer KRAS_G12C SMAD4 48 170 Female 0.07 -0.63 0.69 755.48 1.00 956 41 163 7 TRUE 0.08
colorectal cancer KRAS_G12C SMAD4 33 190 Male 0.15 -0.59 0.87 888.01 1.00 1164 27 184 6 TRUE 0.16
non-small cell lung cancer KRAS_G12C SMAD4 292 74 Female -0.23 -0.96 0.40 1414.33 1.00 1858 285 67 7 TRUE 0.29
non-small cell lung cancer KRAS_G12C SMAD4 179 42 Male -0.05 -0.82 0.70 1277.64 1.00 1393 173 36 6 TRUE 0.05
colorectal cancer KRAS_G12C SMAD4 81 360 Sex:overall 0.12 -0.78 1.10 1233.07 1.00 2120 68 347 13 TRUE 0.09
non-small cell lung cancer KRAS_G12C SMAD4 471 116 Sex:overall -0.14 -1.05 0.68 1424.90 1.00 3251 458 103 13 TRUE 0.12
colorectal cancer KRAS_G12C ATM 49 100 Female -0.89 -2.07 0.16 330.96 1.02 1022 47 98 2 TRUE 0.88
colorectal cancer KRAS_G12C ATM 33 131 Male -0.83 -2.10 0.31 93.14 1.03 1239 31 129 2 TRUE 0.73
non-small cell lung cancer KRAS_G12C ATM 302 174 Female 1.06 0.74 1.36 1159.33 1.00 1808 254 126 48 TRUE 10.40
non-small cell lung cancer KRAS_G12C ATM 182 114 Male 1.13 0.78 1.50 1184.61 1.00 1353 151 83 31 TRUE 9.15
colorectal cancer KRAS_G12C ATM 82 231 Sex:overall -0.84 -2.21 0.44 371.27 1.01 2261 78 227 4 TRUE 0.65
non-small cell lung cancer KRAS_G12C ATM 484 288 Sex:overall 1.09 0.61 1.59 1245.10 1.00 3161 405 209 79 TRUE 4.75
colorectal cancer KRAS_G12C RB1 48 23 Female -1.58 -5.33 0.60 1245.43 1.00 1084 48 23 0 TRUE 0.51
colorectal cancer KRAS_G12C RB1 33 45 Male -1.10 -3.96 0.84 1206.27 1.00 1297 32 44 1 TRUE 0.42
non-small cell lung cancer KRAS_G12C RB1 292 107 Female -0.78 -1.46 -0.19 1362.84 1.00 1827 284 99 8 TRUE 1.83
non-small cell lung cancer KRAS_G12C RB1 179 116 Male -0.86 -1.62 -0.22 1295.51 1.00 1320 173 110 6 TRUE 1.78
colorectal cancer KRAS_G12C RB1 81 68 Sex:overall -1.29 -4.32 0.85 1146.71 1.00 2381 80 67 1 TRUE 0.47
non-small cell lung cancer KRAS_G12C RB1 471 223 Sex:overall -0.81 -1.63 0.04 1521.12 1.00 3147 457 209 14 TRUE 1.23
colorectal cancer KRAS_G12C KMT2D 41 187 Female -2.17 -3.96 -0.78 1067.45 1.00 901 40 186 1 FALSE 2.09
colorectal cancer KRAS_G12C KMT2D 29 201 Male -2.12 -4.13 -0.66 933.77 1.00 1079 28 200 1 FALSE 1.83
non-small cell lung cancer KRAS_G12C KMT2D 283 136 Female 0.40 -0.06 0.84 1316.89 1.00 1766 257 110 26 FALSE 1.06
non-small cell lung cancer KRAS_G12C KMT2D 174 192 Male -0.51 -1.12 0.06 1471.75 1.00 1232 161 179 13 FALSE 1.05
colorectal cancer KRAS_G12C KMT2D 70 388 Sex:overall -2.11 -3.97 -0.57 992.79 1.00 1980 68 386 2 FALSE 1.82
non-small cell lung cancer KRAS_G12C KMT2D 457 328 Sex:overall -0.05 -1.40 1.30 1390.22 1.00 2998 418 289 39 FALSE 0.03
colorectal cancer KRAS_G12C TSC2 41 62 Female -5.64 -12.70 -0.91 95.63 1.03 960 41 62 0 TRUE 1.07
colorectal cancer KRAS_G12C TSC2 29 53 Male -5.64 -12.77 -0.76 95.82 1.03 1159 29 53 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C TSC2 283 46 Female -1.04 -2.36 -0.04 988.85 1.00 1823 281 44 2 TRUE 1.14
non-small cell lung cancer KRAS_G12C TSC2 172 26 Male -0.92 -2.22 0.21 1022.65 1.00 1355 170 24 2 TRUE 0.84
colorectal cancer KRAS_G12C TSC2 70 115 Sex:overall -5.55 -12.59 -0.73 92.40 1.04 2119 70 115 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C TSC2 455 72 Sex:overall -0.97 -2.37 0.19 1064.45 1.00 3178 451 68 4 TRUE 0.89
colorectal cancer KRAS_G12C APC 65 1110 Female 0.17 -0.36 0.71 1331.96 1.00 407 17 1062 48 TRUE 0.27
colorectal cancer KRAS_G12C APC 42 1428 Male 0.08 -0.52 0.68 1275.55 1.00 458 9 1395 33 TRUE 0.09
non-small cell lung cancer KRAS_G12C APC 292 85 Female -0.30 -0.97 0.24 1421.86 1.00 1846 284 77 8 TRUE 0.51
non-small cell lung cancer KRAS_G12C APC 182 72 Male -0.20 -0.83 0.39 1315.68 1.00 1369 174 64 8 TRUE 0.29
colorectal cancer KRAS_G12C APC 107 2538 Sex:overall 0.12 -0.72 1.11 1423.15 1.00 865 26 2457 81 TRUE 0.10
non-small cell lung cancer KRAS_G12C APC 474 157 Sex:overall -0.26 -1.00 0.45 1320.17 1.00 3215 458 141 16 TRUE 0.32
colorectal cancer KRAS_G12C ERBB2 48 38 Female 0.43 -0.81 1.48 1056.68 1.00 1071 45 35 3 TRUE 0.34
colorectal cancer KRAS_G12C ERBB2 33 66 Male 0.24 -1.11 1.29 1003.74 1.00 1273 31 64 2 TRUE 0.16
non-small cell lung cancer KRAS_G12C ERBB2 292 76 Female -3.50 -6.39 -1.66 630.48 1.01 1849 292 76 0 TRUE 2.48
non-small cell lung cancer KRAS_G12C ERBB2 179 53 Male -3.31 -5.80 -1.50 173.78 1.02 1378 178 52 1 TRUE 2.68
colorectal cancer KRAS_G12C ERBB2 81 104 Sex:overall 0.32 -1.12 1.60 1170.34 1.00 2344 76 99 5 TRUE 0.19
non-small cell lung cancer KRAS_G12C ERBB2 471 129 Sex:overall -3.39 -6.01 -1.44 464.33 1.01 3227 470 128 1 TRUE 2.63
colorectal cancer KRAS_G12C JAK1 41 29 Female -5.21 -11.94 -0.50 650.18 1.00 985 41 29 0 TRUE 1.05
colorectal cancer KRAS_G12C JAK1 29 46 Male -5.17 -11.87 -0.53 607.80 1.00 1168 29 46 0 TRUE 1.05
non-small cell lung cancer KRAS_G12C JAK1 283 19 Female -0.43 -1.73 0.68 1437.63 1.00 1849 281 17 2 TRUE 0.31
non-small cell lung cancer KRAS_G12C JAK1 172 33 Male -0.34 -1.48 0.66 1519.50 1.00 1349 169 30 3 TRUE 0.28
colorectal cancer KRAS_G12C JAK1 70 75 Sex:overall -5.13 -11.52 -0.51 536.15 1.00 2153 70 75 0 TRUE 1.08
non-small cell lung cancer KRAS_G12C JAK1 455 52 Sex:overall -0.40 -1.90 1.00 1296.93 1.00 3198 450 47 5 TRUE 0.22
colorectal cancer KRAS_G12C ARID2 41 54 Female -1.73 -4.74 0.26 525.52 1.01 961 40 53 1 FALSE 0.79
colorectal cancer KRAS_G12C ARID2 29 56 Male -2.03 -5.34 0.18 634.44 1.00 1158 29 56 0 FALSE 0.80
non-small cell lung cancer KRAS_G12C ARID2 283 88 Female 0.24 -0.28 0.73 1112.21 1.00 1793 268 73 15 FALSE 0.45
non-small cell lung cancer KRAS_G12C ARID2 173 94 Male 0.18 -0.38 0.71 1426.49 1.00 1308 161 82 12 FALSE 0.29
colorectal cancer KRAS_G12C ARID2 70 110 Sex:overall -1.86 -4.84 0.31 610.95 1.00 2119 69 109 1 FALSE 0.76
non-small cell lung cancer KRAS_G12C ARID2 456 182 Sex:overall 0.20 -0.59 1.00 1393.36 1.00 3101 429 155 27 FALSE 0.21
colorectal cancer KRAS_G12C SOX17 38 52 Female -0.35 -2.00 0.84 597.53 1.01 931 37 51 1 FALSE 0.20
colorectal cancer KRAS_G12C SOX17 28 46 Male 0.04 -1.38 1.40 916.65 1.01 1134 26 44 2 FALSE 0.02
non-small cell lung cancer KRAS_G12C SOX17 283 34 Female 0.73 0.03 1.35 1413.93 1.00 1828 275 26 8 FALSE 1.56
non-small cell lung cancer KRAS_G12C SOX17 172 27 Male 0.78 0.06 1.46 1458.19 1.00 1352 166 21 6 FALSE 1.58
colorectal cancer KRAS_G12C SOX17 66 98 Sex:overall -0.16 -1.95 1.28 720.71 1.01 2065 63 95 3 FALSE 0.07
non-small cell lung cancer KRAS_G12C SOX17 455 61 Sex:overall 0.76 -0.03 1.58 1391.73 1.00 3180 441 47 14 FALSE 1.11
colorectal cancer KRAS_G12C MTOR 41 75 Female -0.19 -1.48 0.80 810.84 1.00 950 38 72 3 TRUE 0.13
colorectal cancer KRAS_G12C MTOR 29 65 Male -0.36 -1.98 0.84 1502.82 1.00 1149 28 64 1 TRUE 0.20
non-small cell lung cancer KRAS_G12C MTOR 284 64 Female 0.58 0.11 1.02 1300.23 1.00 1813 271 51 13 TRUE 2.18
non-small cell lung cancer KRAS_G12C MTOR 173 51 Male 0.61 0.11 1.10 NA 1.00 1338 163 41 10 TRUE 2.10
colorectal cancer KRAS_G12C MTOR 70 140 Sex:overall -0.26 -1.76 1.01 1248.79 1.00 2099 66 136 4 TRUE 0.14
non-small cell lung cancer KRAS_G12C MTOR 457 115 Sex:overall 0.60 0.06 1.15 1126.79 1.00 3151 434 92 23 TRUE 1.48
non-small cell lung cancer KRAS_G12C RFWD2 283 30 Female 0.59 -0.15 1.29 1290.98 1.00 1829 276 23 7 FALSE 0.98
non-small cell lung cancer KRAS_G12C RFWD2 172 27 Male 0.59 -0.22 1.33 1413.14 1.00 1351 167 22 5 FALSE 0.88
non-small cell lung cancer KRAS_G12C RFWD2 455 57 Sex:overall 0.60 -0.35 1.45 1404.29 1.00 3180 443 45 12 FALSE 0.71
colorectal cancer KRAS_G12C IRS1 38 43 Female -1.46 -4.12 0.46 899.06 1.00 941 37 42 1 FALSE 0.68
colorectal cancer KRAS_G12C IRS1 28 54 Male -1.71 -5.00 0.38 902.43 1.00 1127 28 54 0 FALSE 0.69
non-small cell lung cancer KRAS_G12C IRS1 283 38 Female -0.26 -1.10 0.50 146.82 1.03 1820 279 34 4 FALSE 0.27
non-small cell lung cancer KRAS_G12C IRS1 172 35 Male -0.18 -1.02 0.65 96.38 1.04 1343 168 31 4 FALSE 0.18
colorectal cancer KRAS_G12C IRS1 66 97 Sex:overall -1.58 -4.50 0.51 888.26 1.00 2068 65 96 1 FALSE 0.68
non-small cell lung cancer KRAS_G12C IRS1 455 73 Sex:overall -0.22 -1.14 0.64 189.98 1.02 3163 447 65 8 FALSE 0.19
colorectal cancer KRAS_G12C NOTCH1 48 85 Female -5.67 -11.93 -1.46 837.54 1.00 1041 48 85 0 TRUE 1.30
colorectal cancer KRAS_G12C NOTCH1 33 87 Male -5.69 -12.14 -1.43 811.91 1.00 1263 33 87 0 TRUE 1.27
non-small cell lung cancer KRAS_G12C NOTCH1 292 64 Female -0.41 -1.21 0.23 1547.86 1.00 1865 287 59 5 TRUE 0.58
non-small cell lung cancer KRAS_G12C NOTCH1 180 66 Male -0.14 -0.88 0.53 1450.69 1.00 1376 172 58 8 TRUE 0.16
colorectal cancer KRAS_G12C NOTCH1 81 172 Sex:overall -5.61 -12.01 -1.46 780.80 1.00 2304 81 172 0 TRUE 1.28
non-small cell lung cancer KRAS_G12C NOTCH1 472 130 Sex:overall -0.27 -1.20 0.68 1521.57 1.00 3241 459 117 13 TRUE 0.24
colorectal cancer KRAS_G12C NTRK1 41 24 Female -4.67 -11.68 -0.28 772.99 1.00 987 41 24 0 TRUE 0.92
colorectal cancer KRAS_G12C NTRK1 29 40 Male -4.69 -11.43 -0.31 753.60 1.00 1166 29 40 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C NTRK1 283 38 Female 0.80 0.07 1.47 500.01 1.01 1838 272 27 11 TRUE 1.56
non-small cell lung cancer KRAS_G12C NTRK1 172 50 Male 0.30 -0.57 0.98 266.29 1.01 1335 166 44 6 TRUE 0.32
colorectal cancer KRAS_G12C NTRK1 70 64 Sex:overall -4.60 -11.13 -0.17 757.45 1.00 2153 70 64 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C NTRK1 455 88 Sex:overall 0.53 -0.76 1.71 934.78 1.01 3173 438 71 17 TRUE 0.40
non-small cell lung cancer KRAS_G12C INPP4A 283 21 Female 0.84 -0.14 1.81 1303.55 1.00 1838 276 14 7 FALSE 1.06
non-small cell lung cancer KRAS_G12C INPP4A 172 32 Male -0.26 -1.83 0.81 1210.88 1.00 1344 170 30 2 FALSE 0.16
non-small cell lung cancer KRAS_G12C INPP4A 455 53 Sex:overall 0.28 -1.60 2.01 1460.46 1.00 3182 446 44 9 FALSE 0.12
colorectal cancer KRAS_G12C CASP8 38 38 Female -5.06 -12.95 -0.94 189.47 1.02 945 38 38 0 FALSE 1.00
colorectal cancer KRAS_G12C CASP8 28 58 Male -5.02 -13.02 -0.82 188.28 1.02 1126 28 58 0 FALSE 0.99
colorectal cancer KRAS_G12C CASP8 66 96 Sex:overall -4.96 -12.86 -0.90 181.03 1.01 2071 66 96 0 FALSE 1.01
colorectal cancer KRAS_G12C SETD2 41 34 Female -4.94 -12.60 -0.71 311.17 1.01 980 41 34 0 FALSE 0.96
colorectal cancer KRAS_G12C SETD2 29 79 Male -4.99 -12.24 -0.92 290.81 1.02 1142 29 79 0 FALSE 1.00
non-small cell lung cancer KRAS_G12C SETD2 287 131 Female 0.25 -0.16 0.67 1124.02 1.00 1775 264 108 23 FALSE 0.62
non-small cell lung cancer KRAS_G12C SETD2 173 94 Male 0.12 -0.41 0.57 1478.06 1.00 1304 163 84 10 FALSE 0.21
colorectal cancer KRAS_G12C SETD2 70 113 Sex:overall -4.85 -11.99 -0.77 285.25 1.02 2122 70 113 0 FALSE 0.99
non-small cell lung cancer KRAS_G12C SETD2 460 225 Sex:overall 0.19 -0.40 0.75 1215.59 1.00 3079 427 192 33 FALSE 0.28
colorectal cancer KRAS_G12C PBRM1 41 38 Female -4.92 -11.53 -0.74 1220.34 1.00 975 41 38 0 TRUE 1.08
colorectal cancer KRAS_G12C PBRM1 29 56 Male -4.87 -11.62 -0.68 1147.77 1.00 1158 29 56 0 TRUE 1.05
non-small cell lung cancer KRAS_G12C PBRM1 283 57 Female -0.08 -0.77 0.60 61.04 1.02 1823 275 49 8 TRUE 0.07
non-small cell lung cancer KRAS_G12C PBRM1 172 57 Male -0.11 -0.81 0.58 60.29 1.03 1334 166 51 6 TRUE 0.10
colorectal cancer KRAS_G12C PBRM1 70 94 Sex:overall -4.80 -11.40 -0.71 1174.49 1.00 2133 70 94 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C PBRM1 455 114 Sex:overall -0.10 -0.83 0.72 93.43 1.02 3157 441 100 14 TRUE 0.08
colorectal cancer KRAS_G12C EPHA3 41 52 Female -0.85 -4.59 0.67 83.97 1.04 964 39 50 2 FALSE 0.39
colorectal cancer KRAS_G12C EPHA3 29 61 Male -1.33 -4.82 0.39 193.12 1.02 1150 29 61 0 FALSE 0.50
non-small cell lung cancer KRAS_G12C EPHA3 289 146 Female 0.50 0.17 0.91 20.99 1.15 1756 257 114 32 FALSE 1.70
non-small cell lung cancer KRAS_G12C EPHA3 172 96 Male 0.26 -0.31 0.73 1139.97 1.00 1302 161 85 11 FALSE 0.50
colorectal cancer KRAS_G12C EPHA3 70 113 Sex:overall -1.09 -4.62 0.71 121.37 1.03 2114 68 111 2 FALSE 0.45
non-small cell lung cancer KRAS_G12C EPHA3 461 242 Sex:overall 0.39 -0.27 0.98 829.28 1.02 3058 418 199 43 FALSE 0.60
colorectal cancer KRAS_G12C KIT 48 23 Female 0.44 -1.08 1.73 1227.68 1.00 1084 46 21 2 TRUE 0.27
colorectal cancer KRAS_G12C KIT 33 31 Male 0.32 -1.36 1.65 1346.29 1.00 1304 32 30 1 TRUE 0.17
non-small cell lung cancer KRAS_G12C KIT 292 38 Female 0.80 0.19 1.47 1501.62 1.00 1894 281 27 11 TRUE 1.84
non-small cell lung cancer KRAS_G12C KIT 179 43 Male 0.59 -0.15 1.20 1533.46 1.00 1396 172 36 7 TRUE 1.06
colorectal cancer KRAS_G12C KIT 81 54 Sex:overall 0.40 -1.26 1.86 1227.28 1.00 2388 78 51 3 TRUE 0.21
non-small cell lung cancer KRAS_G12C KIT 471 81 Sex:overall 0.68 -0.26 1.65 1502.65 1.00 3290 453 63 18 TRUE 0.78
colorectal cancer KRAS_G12C KDR 48 26 Female -0.45 -2.35 1.03 1135.62 1.00 1082 47 25 1 TRUE 0.21
colorectal cancer KRAS_G12C KDR 33 49 Male -0.47 -2.33 1.00 1234.06 1.00 1291 32 48 1 TRUE 0.23
non-small cell lung cancer KRAS_G12C KDR 294 94 Female 0.22 -0.29 0.71 1144.68 1.00 1848 278 78 16 TRUE 0.41
non-small cell lung cancer KRAS_G12C KDR 179 60 Male 0.14 -0.50 0.71 1436.54 1.00 1377 172 53 7 TRUE 0.20
colorectal cancer KRAS_G12C KDR 81 75 Sex:overall -0.45 -2.48 1.27 1279.09 1.00 2373 79 73 2 TRUE 0.19
non-small cell lung cancer KRAS_G12C KDR 473 154 Sex:overall 0.17 -0.50 0.83 1312.47 1.00 3225 450 131 23 TRUE 0.21
colorectal cancer KRAS_G12C RICTOR 41 26 Female -0.91 -4.40 1.00 1138.19 1.00 986 41 26 0 FALSE 0.28
colorectal cancer KRAS_G12C RICTOR 29 44 Male -0.09 -1.97 1.44 1404.35 1.00 1171 27 42 2 FALSE 0.04
non-small cell lung cancer KRAS_G12C RICTOR 283 39 Female -0.35 -1.34 0.51 1273.72 1.00 1830 279 35 4 FALSE 0.34
non-small cell lung cancer KRAS_G12C RICTOR 172 25 Male -0.39 -1.49 0.51 1277.95 1.00 1357 170 23 2 FALSE 0.35
colorectal cancer KRAS_G12C RICTOR 70 70 Sex:overall -0.47 -3.02 1.42 1156.19 1.00 2157 68 68 2 FALSE 0.17
non-small cell lung cancer KRAS_G12C RICTOR 455 64 Sex:overall -0.37 -1.47 0.64 1250.73 1.00 3187 449 58 6 FALSE 0.30
colorectal cancer KRAS_G12C RAD50 41 21 Female -1.37 -4.82 0.77 1249.10 1.00 991 41 21 0 FALSE 0.45
colorectal cancer KRAS_G12C RAD50 29 39 Male -0.95 -3.81 1.01 1381.41 1.00 1171 28 38 1 FALSE 0.35
colorectal cancer KRAS_G12C RAD50 70 60 Sex:overall -1.13 -4.27 1.05 1348.36 1.00 2162 69 59 1 FALSE 0.41
colorectal cancer KRAS_G12C CSF1R 48 21 Female -4.72 -11.94 -0.25 1122.74 1.00 1084 48 21 0 TRUE 0.92
colorectal cancer KRAS_G12C CSF1R 33 35 Male -4.69 -11.92 -0.43 1039.87 1.00 1302 33 35 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C CSF1R 292 36 Female 0.27 -0.57 0.99 1121.53 1.00 1893 287 31 5 TRUE 0.32
non-small cell lung cancer KRAS_G12C CSF1R 179 33 Male 0.50 -0.20 1.26 1260.79 1.00 1403 172 26 7 TRUE 0.78
colorectal cancer KRAS_G12C CSF1R 81 56 Sex:overall -4.62 -11.52 -0.29 1016.93 1.00 2386 81 56 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C CSF1R 471 69 Sex:overall 0.39 -0.48 1.28 1299.07 1.00 3296 459 57 12 TRUE 0.40
non-small cell lung cancer KRAS_G12C PARK2 283 39 Female 0.23 -0.55 0.98 1116.57 1.00 1832 276 32 7 FALSE 0.27
non-small cell lung cancer KRAS_G12C PARK2 172 26 Male 0.15 -0.75 0.93 1400.32 1.00 1355 169 23 3 FALSE 0.14
non-small cell lung cancer KRAS_G12C PARK2 455 65 Sex:overall 0.20 -0.73 1.00 1308.82 1.00 3187 445 55 10 FALSE 0.18
non-small cell lung cancer KRAS_G12C NTRK2 284 36 Female 0.41 -0.29 1.05 1189.14 1.00 1837 277 29 7 FALSE 0.62
non-small cell lung cancer KRAS_G12C NTRK2 172 31 Male 0.40 -0.38 1.10 1366.34 1.00 1354 167 26 5 FALSE 0.53
non-small cell lung cancer KRAS_G12C NTRK2 456 67 Sex:overall 0.40 -0.43 1.15 1325.86 1.00 3191 444 55 12 FALSE 0.46
colorectal cancer KRAS_G12C PTCH1 41 67 Female -2.02 -4.72 -0.14 590.39 1.01 955 40 66 1 TRUE 1.01
colorectal cancer KRAS_G12C PTCH1 29 78 Male -2.26 -5.34 -0.20 971.60 1.00 1148 29 78 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C PTCH1 283 39 Female 0.57 -0.18 1.30 1364.66 1.00 1836 273 29 10 TRUE 0.90
non-small cell lung cancer KRAS_G12C PTCH1 172 23 Male -0.16 -1.85 0.91 1251.03 1.00 1356 171 22 1 TRUE 0.08
colorectal cancer KRAS_G12C PTCH1 70 145 Sex:overall -2.13 -4.92 -0.17 639.80 1.00 2103 69 144 1 TRUE 1.04
non-small cell lung cancer KRAS_G12C PTCH1 455 62 Sex:overall 0.22 -1.41 1.34 1560.90 1.00 3192 444 51 11 TRUE 0.12
colorectal cancer KRAS_G12C TET1 38 40 Female -1.51 -4.27 0.39 1197.60 1.00 944 37 39 1 FALSE 0.70
colorectal cancer KRAS_G12C TET1 28 63 Male -1.86 -5.15 0.12 1409.39 1.00 1132 28 63 0 FALSE 0.77
non-small cell lung cancer KRAS_G12C TET1 284 63 Female 0.02 -0.61 0.62 1465.47 1.00 1802 274 53 10 FALSE 0.02
non-small cell lung cancer KRAS_G12C TET1 172 63 Male -0.19 -1.01 0.48 1351.93 1.00 1323 167 58 5 FALSE 0.21
colorectal cancer KRAS_G12C TET1 66 103 Sex:overall -1.68 -4.76 0.40 1368.57 1.00 2076 65 102 1 FALSE 0.73
non-small cell lung cancer KRAS_G12C TET1 456 126 Sex:overall -0.08 -0.97 0.74 1443.02 1.00 3125 441 111 15 FALSE 0.06
colorectal cancer KRAS_G12C FGFR2 48 21 Female -3.66 -11.30 0.16 7.71 1.16 1085 48 21 0 TRUE 0.61
colorectal cancer KRAS_G12C FGFR2 33 32 Male -3.62 -10.91 0.13 7.48 1.16 1301 33 32 0 TRUE 0.61
colorectal cancer KRAS_G12C FGFR2 81 53 Sex:overall -3.58 -10.91 0.21 7.44 1.16 2386 81 53 0 TRUE 0.61
colorectal cancer KRAS_G12C TBX3 41 37 Female -5.03 -12.56 -0.35 534.06 1.00 978 41 37 0 FALSE 0.96
colorectal cancer KRAS_G12C TBX3 29 43 Male -5.01 -12.72 -0.26 554.88 1.00 1169 29 43 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C TBX3 283 76 Female 0.71 0.14 1.24 1465.49 1.00 1811 263 56 20 FALSE 2.01
non-small cell lung cancer KRAS_G12C TBX3 172 61 Male -0.19 -1.36 0.60 1196.74 1.00 1327 168 57 4 FALSE 0.15
colorectal cancer KRAS_G12C TBX3 70 80 Sex:overall -4.96 -12.28 -0.28 531.30 1.00 2147 70 80 0 FALSE 0.96
non-small cell lung cancer KRAS_G12C TBX3 455 137 Sex:overall 0.24 -1.23 1.31 1403.82 1.00 3138 431 113 24 FALSE 0.16
colorectal cancer KRAS_G12C HNF1A 48 27 Female -4.51 -12.10 -0.33 840.24 1.00 1077 48 27 0 TRUE 0.87
colorectal cancer KRAS_G12C HNF1A 33 25 Male -4.52 -12.27 -0.26 874.85 1.00 1307 33 25 0 TRUE 0.85
colorectal cancer KRAS_G12C HNF1A 81 52 Sex:overall -4.41 -11.79 -0.08 914.72 1.00 2384 81 52 0 TRUE 0.84
colorectal cancer KRAS_G12C DICER1 41 29 Female -4.89 -12.44 -0.62 1075.38 1.00 982 41 29 0 TRUE 0.96
colorectal cancer KRAS_G12C DICER1 29 47 Male -4.80 -11.81 -0.46 1088.07 1.00 1170 29 47 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C DICER1 283 52 Female 0.23 -0.42 0.86 1114.51 1.00 1827 273 42 10 TRUE 0.33
non-small cell lung cancer KRAS_G12C DICER1 172 38 Male 0.03 -0.92 0.68 331.79 1.02 1344 169 35 3 TRUE 0.02
colorectal cancer KRAS_G12C DICER1 70 76 Sex:overall -4.75 -11.72 -0.45 1068.30 1.00 2152 70 76 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C DICER1 455 90 Sex:overall 0.13 -0.77 0.87 1419.87 1.00 3171 442 77 13 TRUE 0.12
colorectal cancer KRAS_G12C SMAD3 41 46 Female -1.56 -4.08 0.27 992.68 1.00 971 40 45 1 TRUE 0.76
colorectal cancer KRAS_G12C SMAD3 29 61 Male -1.88 -4.94 0.02 795.21 1.00 1151 29 61 0 TRUE 0.85
colorectal cancer KRAS_G12C SMAD3 70 107 Sex:overall -1.70 -4.39 0.26 903.82 1.00 2122 69 106 1 TRUE 0.78
colorectal cancer KRAS_G12C NTRK3 41 24 Female -1.64 -5.44 0.50 1177.16 1.00 988 41 24 0 FALSE 0.56
colorectal cancer KRAS_G12C NTRK3 29 46 Male -1.13 -4.03 0.76 1318.89 1.00 1165 28 45 1 FALSE 0.44
non-small cell lung cancer KRAS_G12C NTRK3 285 106 Female 0.98 0.58 1.38 1391.46 1.00 1799 254 75 31 FALSE 5.81
non-small cell lung cancer KRAS_G12C NTRK3 174 101 Male 0.82 0.35 1.24 1414.65 1.00 1309 154 81 20 FALSE 3.63
colorectal cancer KRAS_G12C NTRK3 70 70 Sex:overall -1.34 -4.20 0.88 1389.40 1.00 2153 69 69 1 FALSE 0.49
non-small cell lung cancer KRAS_G12C NTRK3 459 207 Sex:overall 0.90 0.23 1.65 1413.60 1.00 3108 408 156 51 FALSE 1.97
colorectal cancer KRAS_G12C AXIN1 41 33 Female -4.75 -11.38 -0.70 1013.62 1.00 980 41 33 0 FALSE 1.03
colorectal cancer KRAS_G12C AXIN1 29 38 Male -4.77 -11.23 -0.59 948.37 1.00 1172 29 38 0 FALSE 1.04
colorectal cancer KRAS_G12C AXIN1 70 71 Sex:overall -4.70 -11.10 -0.64 1026.35 1.00 2152 70 71 0 FALSE 1.03
colorectal cancer KRAS_G12C GRIN2A 41 62 Female -0.09 -1.28 0.93 568.19 1.00 954 38 59 3 FALSE 0.06
colorectal cancer KRAS_G12C GRIN2A 29 74 Male -0.30 -1.67 0.85 717.35 1.00 1142 28 73 1 FALSE 0.19
non-small cell lung cancer KRAS_G12C GRIN2A 284 102 Female 0.27 -0.20 0.75 588.27 1.01 1787 265 83 19 FALSE 0.54
non-small cell lung cancer KRAS_G12C GRIN2A 174 91 Male 0.04 -0.60 0.56 1266.99 1.00 1299 165 82 9 FALSE 0.05
colorectal cancer KRAS_G12C GRIN2A 70 136 Sex:overall -0.18 -1.64 1.09 847.85 1.00 2096 66 132 4 FALSE 0.10
non-small cell lung cancer KRAS_G12C GRIN2A 458 193 Sex:overall 0.15 -0.55 0.76 1052.83 1.00 3086 430 165 28 FALSE 0.18
colorectal cancer KRAS_G12C PALB2 41 20 Female -4.61 -11.99 -0.22 510.30 1.00 991 41 20 0 TRUE 0.87
colorectal cancer KRAS_G12C PALB2 29 36 Male -4.61 -11.81 -0.20 472.12 1.01 1171 29 36 0 TRUE 0.86
non-small cell lung cancer KRAS_G12C PALB2 283 31 Female 0.46 -0.30 1.21 1207.38 1.00 1842 276 24 7 TRUE 0.64
non-small cell lung cancer KRAS_G12C PALB2 172 29 Male 0.37 -0.50 1.09 1040.23 1.00 1354 168 25 4 TRUE 0.44
colorectal cancer KRAS_G12C PALB2 70 56 Sex:overall -4.51 -11.56 -0.21 488.36 1.00 2162 70 56 0 TRUE 0.86
non-small cell lung cancer KRAS_G12C PALB2 455 60 Sex:overall 0.43 -0.44 1.28 1188.59 1.00 3196 444 49 11 TRUE 0.45
colorectal cancer KRAS_G12C CTCF 41 40 Female -0.44 -2.47 0.98 527.45 1.01 978 39 38 2 FALSE 0.21
colorectal cancer KRAS_G12C CTCF 29 50 Male -1.11 -4.63 0.65 1033.58 1.00 1161 29 50 0 FALSE 0.35
colorectal cancer KRAS_G12C CTCF 70 90 Sex:overall -0.74 -3.30 1.01 1117.87 1.00 2139 68 88 2 FALSE 0.29
colorectal cancer KRAS_G12C CDH1 48 21 Female -4.61 -10.51 -0.54 745.43 1.00 1089 48 21 0 TRUE 1.26
colorectal cancer KRAS_G12C CDH1 33 33 Male -4.56 -10.27 -0.46 660.59 1.00 1300 33 33 0 TRUE 1.25
colorectal cancer KRAS_G12C CDH1 81 54 Sex:overall -4.53 -10.26 -0.46 629.15 1.00 2389 81 54 0 TRUE 1.27
colorectal cancer KRAS_G12C CDK12 41 42 Female -1.32 -4.40 0.56 951.91 1.01 974 41 42 0 FALSE 0.48
colorectal cancer KRAS_G12C CDK12 30 48 Male -0.63 -2.13 1.20 7.03 1.18 1165 28 46 2 FALSE 0.29
non-small cell lung cancer KRAS_G12C CDK12 283 31 Female -0.62 -1.80 0.32 1391.65 1.00 1836 281 29 2 FALSE 0.59
non-small cell lung cancer KRAS_G12C CDK12 172 28 Male -0.47 -1.63 0.53 1472.83 1.00 1354 169 25 3 FALSE 0.40
colorectal cancer KRAS_G12C CDK12 71 90 Sex:overall -0.96 -2.98 0.91 27.42 1.07 2139 69 88 2 FALSE 0.46
non-small cell lung cancer KRAS_G12C CDK12 455 59 Sex:overall -0.53 -1.69 0.52 1464.28 1.00 3190 450 54 5 FALSE 0.42
non-small cell lung cancer KRAS_G12C STK11 294 295 Female 0.96 0.69 1.23 1360.57 1.00 1709 221 222 73 TRUE 11.28
non-small cell lung cancer KRAS_G12C STK11 182 248 Male 1.03 0.76 1.34 1304.97 1.00 1242 125 191 57 TRUE 11.26
non-small cell lung cancer KRAS_G12C STK11 476 543 Sex:overall 1.00 0.53 1.49 1529.86 1.00 2951 346 413 130 TRUE 4.24
colorectal cancer KRAS_G12C DNMT1 38 39 Female -4.69 -11.13 -0.50 404.69 1.02 942 38 39 0 FALSE 1.07
colorectal cancer KRAS_G12C DNMT1 28 51 Male -4.66 -11.09 -0.61 515.81 1.02 1131 28 51 0 FALSE 1.06
colorectal cancer KRAS_G12C DNMT1 66 90 Sex:overall -4.58 -10.88 -0.48 451.46 1.02 2073 66 90 0 FALSE 1.06
colorectal cancer KRAS_G12C BRD4 41 31 Female -1.16 -4.82 0.66 1282.06 1.00 979 41 31 0 FALSE 0.38
colorectal cancer KRAS_G12C BRD4 30 57 Male -0.32 -2.24 1.17 1243.62 1.00 1155 28 55 2 FALSE 0.15
non-small cell lung cancer KRAS_G12C BRD4 284 27 Female 0.06 -0.90 0.88 572.11 1.00 1843 279 22 5 FALSE 0.05
non-small cell lung cancer KRAS_G12C BRD4 172 26 Male -0.13 -1.22 0.76 919.21 1.00 1354 170 24 2 FALSE 0.09
colorectal cancer KRAS_G12C BRD4 71 88 Sex:overall -0.70 -3.29 1.24 1548.37 1.00 2134 69 86 2 FALSE 0.27
non-small cell lung cancer KRAS_G12C BRD4 456 53 Sex:overall -0.02 -1.11 0.91 1127.02 1.00 3197 449 46 7 FALSE 0.01
colorectal cancer KRAS_G12C ASXL1 41 49 Female -0.84 -3.09 0.71 77.70 1.04 969 39 47 2 TRUE 0.47
colorectal cancer KRAS_G12C ASXL1 29 60 Male -1.27 -3.95 0.46 204.23 1.02 1148 29 60 0 TRUE 0.55
non-small cell lung cancer KRAS_G12C ASXL1 283 40 Female 0.19 -0.65 0.96 1359.90 1.00 1833 275 32 8 TRUE 0.18
non-small cell lung cancer KRAS_G12C ASXL1 172 46 Male -0.53 -1.89 0.40 1391.19 1.00 1347 170 44 2 TRUE 0.44
colorectal cancer KRAS_G12C ASXL1 70 109 Sex:overall -1.06 -3.37 0.70 112.17 1.03 2117 68 107 2 TRUE 0.52
non-small cell lung cancer KRAS_G12C ASXL1 455 86 Sex:overall -0.17 -1.53 1.12 1488.10 1.00 3180 445 76 10 TRUE 0.10
colorectal cancer KRAS_G12C EP300 41 53 Female -2.10 -5.44 -0.08 1214.60 1.00 969 41 53 0 TRUE 0.86
colorectal cancer KRAS_G12C EP300 29 72 Male -1.71 -4.37 0.24 1305.45 1.00 1145 28 71 1 TRUE 0.79
non-small cell lung cancer KRAS_G12C EP300 283 54 Female 0.07 -0.63 0.70 1256.66 1.00 1826 274 45 9 TRUE 0.08
non-small cell lung cancer KRAS_G12C EP300 172 54 Male -0.18 -1.09 0.51 741.24 1.00 1332 168 50 4 TRUE 0.18
colorectal cancer KRAS_G12C EP300 70 125 Sex:overall -1.87 -4.94 0.30 1292.52 1.00 2114 69 124 1 TRUE 0.81
non-small cell lung cancer KRAS_G12C EP300 455 108 Sex:overall -0.05 -1.06 0.80 1229.09 1.00 3158 442 95 13 TRUE 0.04
colorectal cancer KRAS_G12C ERBB4 48 60 Female -1.08 -3.12 0.34 1372.44 1.00 1051 47 59 1 TRUE 0.68
colorectal cancer KRAS_G12C ERBB4 33 78 Male -1.07 -3.06 0.42 1197.31 1.00 1267 32 77 1 TRUE 0.67
non-small cell lung cancer KRAS_G12C ERBB4 293 108 Female -0.50 -1.08 0.04 1235.64 1.00 1837 282 97 11 TRUE 1.04
non-small cell lung cancer KRAS_G12C ERBB4 179 85 Male -0.67 -1.45 -0.04 1163.77 1.01 1363 175 81 4 TRUE 1.18
colorectal cancer KRAS_G12C ERBB4 81 138 Sex:overall -1.05 -3.04 0.51 1376.45 1.00 2318 79 136 2 TRUE 0.62
non-small cell lung cancer KRAS_G12C ERBB4 472 193 Sex:overall -0.57 -1.35 0.14 1315.99 1.00 3200 457 178 15 TRUE 0.85
colorectal cancer KRAS_G12C MDC1 38 27 Female -4.84 -13.26 -0.18 219.29 1.01 952 38 27 0 FALSE 0.86
colorectal cancer KRAS_G12C MDC1 28 38 Male -4.83 -13.35 -0.20 224.99 1.01 1144 28 38 0 FALSE 0.85
non-small cell lung cancer KRAS_G12C MDC1 286 52 Female 0.13 -0.58 0.83 1369.21 1.00 1813 276 42 10 FALSE 0.14
non-small cell lung cancer KRAS_G12C MDC1 172 43 Male -0.38 -1.70 0.48 1299.82 1.00 1337 170 41 2 FALSE 0.29
colorectal cancer KRAS_G12C MDC1 66 65 Sex:overall -4.76 -13.16 -0.28 217.21 1.01 2096 66 65 0 FALSE 0.85
non-small cell lung cancer KRAS_G12C MDC1 458 95 Sex:overall -0.11 -1.39 0.89 1577.98 1.00 3150 446 83 12 FALSE 0.07
colorectal cancer KRAS_G12C RECQL4 38 30 Female -4.88 -11.69 -0.44 1417.43 1.00 951 38 30 0 TRUE 1.04
colorectal cancer KRAS_G12C RECQL4 28 51 Male -4.87 -11.55 -0.62 1303.22 1.00 1131 28 51 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C RECQL4 283 36 Female -0.93 -2.19 0.14 620.15 1.00 1821 281 34 2 TRUE 0.94
non-small cell lung cancer KRAS_G12C RECQL4 172 28 Male -0.84 -2.09 0.27 765.05 1.00 1347 170 26 2 TRUE 0.79
colorectal cancer KRAS_G12C RECQL4 66 81 Sex:overall -4.78 -10.97 -0.35 1403.36 1.00 2082 66 81 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C RECQL4 455 64 Sex:overall -0.89 -2.17 0.24 697.36 1.00 3168 451 60 4 TRUE 0.81
colorectal cancer KRAS_G12C MED12 42 54 Female 0.59 -0.45 1.49 1433.77 1.00 966 38 50 4 TRUE 0.64
colorectal cancer KRAS_G12C MED12 29 54 Male 0.48 -0.68 1.44 1329.34 1.00 1160 27 52 2 TRUE 0.42
non-small cell lung cancer KRAS_G12C MED12 285 137 Female -0.20 -0.73 0.30 1521.62 1.00 1752 270 122 15 TRUE 0.34
non-small cell lung cancer KRAS_G12C MED12 173 39 Male 0.16 -0.71 0.96 1052.97 1.00 1346 167 33 6 TRUE 0.16
colorectal cancer KRAS_G12C MED12 71 108 Sex:overall 0.55 -0.71 1.79 1455.17 1.00 2126 65 102 6 TRUE 0.43
non-small cell lung cancer KRAS_G12C MED12 458 176 Sex:overall -0.01 -1.27 1.30 1244.25 1.00 3098 437 155 21 TRUE 0.00
colorectal cancer KRAS_G12C ERCC5 38 31 Female -1.51 -4.86 0.70 842.62 1.00 953 38 31 0 TRUE 0.52
colorectal cancer KRAS_G12C ERCC5 28 27 Male -0.98 -3.76 1.12 257.64 1.01 1147 27 26 1 TRUE 0.34
non-small cell lung cancer KRAS_G12C ERCC5 283 39 Female 0.38 -0.32 1.01 223.06 1.02 1822 275 31 8 TRUE 0.53
non-small cell lung cancer KRAS_G12C ERCC5 172 34 Male 0.26 -0.63 0.99 235.60 1.01 1348 168 30 4 TRUE 0.27
colorectal cancer KRAS_G12C ERCC5 66 58 Sex:overall -1.22 -4.15 0.93 526.21 1.01 2100 65 57 1 TRUE 0.43
non-small cell lung cancer KRAS_G12C ERCC5 455 73 Sex:overall 0.31 -0.63 1.09 337.30 1.01 3170 443 61 12 TRUE 0.30
colorectal cancer KRAS_G12C PIK3CD 38 34 Female -0.14 -1.89 1.17 308.23 1.01 949 36 32 2 FALSE 0.07
colorectal cancer KRAS_G12C PIK3CD 28 35 Male -0.65 -3.62 1.14 456.03 1.00 1142 28 35 0 FALSE 0.22
colorectal cancer KRAS_G12C PIK3CD 66 69 Sex:overall -0.39 -2.64 1.20 470.76 1.00 2091 64 67 2 FALSE 0.15
colorectal cancer KRAS_G12C BRCA1 41 28 Female -5.19 -12.27 -0.52 624.72 1.00 984 41 28 0 TRUE 1.02
colorectal cancer KRAS_G12C BRCA1 29 51 Male -5.14 -12.54 -0.45 667.61 1.00 1165 29 51 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C BRCA1 283 50 Female 0.23 -0.44 0.87 1243.10 1.01 1826 274 41 9 TRUE 0.32
non-small cell lung cancer KRAS_G12C BRCA1 172 47 Male 0.10 -0.71 0.74 958.56 1.00 1338 167 42 5 TRUE 0.10
colorectal cancer KRAS_G12C BRCA1 70 79 Sex:overall -5.04 -11.97 -0.50 602.89 1.00 2149 70 79 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C BRCA1 455 97 Sex:overall 0.16 -0.70 0.91 1439.25 1.00 3164 441 83 14 TRUE 0.16
colorectal cancer KRAS_G12C RBM10 41 41 Female -5.03 -11.99 -0.68 263.37 1.01 975 41 41 0 FALSE 1.07
colorectal cancer KRAS_G12C RBM10 29 31 Male -5.01 -11.90 -0.41 255.29 1.01 1173 29 31 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C RBM10 287 239 Female 0.57 0.24 0.88 1401.85 1.00 1686 239 191 48 FALSE 3.29
non-small cell lung cancer KRAS_G12C RBM10 172 144 Male 0.53 0.13 0.90 1437.87 1.00 1261 148 120 24 FALSE 2.23
colorectal cancer KRAS_G12C RBM10 70 72 Sex:overall -4.93 -11.74 -0.39 240.53 1.01 2148 70 72 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C RBM10 459 383 Sex:overall 0.55 0.07 1.03 1331.67 1.00 2947 387 311 72 FALSE 1.30
colorectal cancer KRAS_G12C TSC1 41 27 Female -1.10 -3.97 0.88 1341.23 1.00 986 40 26 1 TRUE 0.43
colorectal cancer KRAS_G12C TSC1 29 40 Male -1.54 -5.08 0.61 1371.08 1.00 1173 29 40 0 TRUE 0.50
non-small cell lung cancer KRAS_G12C TSC1 283 30 Female 0.37 -0.35 1.08 845.55 1.00 1841 277 24 6 TRUE 0.52
non-small cell lung cancer KRAS_G12C TSC1 172 27 Male 0.35 -0.42 1.08 917.90 1.00 1355 168 23 4 TRUE 0.43
colorectal cancer KRAS_G12C TSC1 70 67 Sex:overall -1.27 -4.47 1.07 1424.44 1.00 2159 69 66 1 TRUE 0.46
non-small cell lung cancer KRAS_G12C TSC1 455 57 Sex:overall 0.35 -0.51 1.16 895.49 1.00 3196 445 47 10 TRUE 0.39
colorectal cancer KRAS_G12C FLCN 41 30 Female -4.70 -11.41 -0.29 1336.05 1.00 981 41 30 0 TRUE 0.95
colorectal cancer KRAS_G12C FLCN 29 24 Male -4.70 -11.66 -0.18 1292.18 1.00 1184 29 24 0 TRUE 0.92
colorectal cancer KRAS_G12C FLCN 70 54 Sex:overall -4.59 -11.55 -0.24 1351.06 1.00 2165 70 54 0 TRUE 0.94
colorectal cancer KRAS_G12C NF1 41 55 Female -1.83 -4.45 0.01 919.97 1.00 966 40 54 1 TRUE 0.94
colorectal cancer KRAS_G12C NF1 29 87 Male -2.24 -5.57 -0.10 1111.89 1.00 1142 29 87 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C NF1 284 165 Female -0.32 -0.77 0.14 1485.34 1.00 1740 266 147 18 TRUE 0.78
non-small cell lung cancer KRAS_G12C NF1 174 150 Male -0.42 -0.95 0.05 1242.37 1.00 1258 163 139 11 TRUE 0.98
colorectal cancer KRAS_G12C NF1 70 142 Sex:overall -1.99 -4.94 0.03 1044.07 1.00 2108 69 141 1 TRUE 0.91
non-small cell lung cancer KRAS_G12C NF1 458 315 Sex:overall -0.37 -1.05 0.25 1380.78 1.00 2998 429 286 29 TRUE 0.56
colorectal cancer KRAS_G12C FLT1 41 30 Female -4.84 -11.43 -0.69 982.56 1.00 984 41 30 0 FALSE 1.12
colorectal cancer KRAS_G12C FLT1 29 52 Male -4.85 -11.60 -0.68 970.09 1.00 1162 29 52 0 FALSE 1.11
non-small cell lung cancer KRAS_G12C FLT1 285 75 Female 0.43 -0.06 0.90 1333.67 1.00 1807 272 62 13 FALSE 1.07
non-small cell lung cancer KRAS_G12C FLT1 173 61 Male 0.55 0.03 1.10 1295.76 1.00 1333 161 49 12 FALSE 1.37
colorectal cancer KRAS_G12C FLT1 70 82 Sex:overall -4.79 -11.35 -0.59 958.33 1.00 2146 70 82 0 FALSE 1.10
non-small cell lung cancer KRAS_G12C FLT1 458 136 Sex:overall 0.49 -0.16 1.13 1534.17 1.00 3140 433 111 25 FALSE 0.81
colorectal cancer KRAS_G12C RPTOR 41 32 Female -1.56 -4.91 0.46 1051.03 1.00 978 41 32 0 FALSE 0.54
colorectal cancer KRAS_G12C RPTOR 29 38 Male -1.07 -3.65 0.85 1124.66 1.00 1173 28 37 1 FALSE 0.44
non-small cell lung cancer KRAS_G12C RPTOR 283 34 Female -0.15 -1.14 0.63 179.66 1.03 1834 280 31 3 FALSE 0.13
non-small cell lung cancer KRAS_G12C RPTOR 172 31 Male 0.08 -0.81 0.89 1109.85 1.00 1353 167 26 5 FALSE 0.07
colorectal cancer KRAS_G12C RPTOR 70 70 Sex:overall -1.28 -4.05 0.82 1133.15 1.00 2151 69 69 1 FALSE 0.51
non-small cell lung cancer KRAS_G12C RPTOR 455 65 Sex:overall -0.03 -1.04 0.90 1053.48 1.01 3187 447 57 8 FALSE 0.02
colorectal cancer KRAS_G12C RASA1 41 30 Female -1.15 -3.90 0.74 920.93 1.00 984 40 29 1 FALSE 0.49
colorectal cancer KRAS_G12C RASA1 29 43 Male -1.48 -4.63 0.44 986.84 1.00 1174 29 43 0 FALSE 0.57
non-small cell lung cancer KRAS_G12C RASA1 283 47 Female -0.79 -1.81 0.03 1511.72 1.00 1823 279 43 4 FALSE 1.02
non-small cell lung cancer KRAS_G12C RASA1 172 51 Male -0.97 -2.06 -0.06 1204.13 1.00 1329 170 49 2 FALSE 1.19
colorectal cancer KRAS_G12C RASA1 70 73 Sex:overall -1.27 -4.16 0.65 1046.27 1.00 2158 69 72 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C RASA1 455 98 Sex:overall -0.86 -2.05 0.24 1347.57 1.00 3152 449 92 6 FALSE 0.85
colorectal cancer KRAS_G12C EPHA5 41 58 Female -1.07 -3.02 0.32 1370.71 1.00 959 40 57 1 FALSE 0.68
colorectal cancer KRAS_G12C EPHA5 29 86 Male -1.07 -3.00 0.34 1411.25 1.00 1138 28 85 1 FALSE 0.68
non-small cell lung cancer KRAS_G12C EPHA5 283 147 Female 0.73 0.38 1.08 1376.62 1.00 1764 247 111 36 FALSE 4.47
non-small cell lung cancer KRAS_G12C EPHA5 174 113 Male 0.59 0.13 0.98 1131.66 1.00 1294 156 95 18 FALSE 2.25
colorectal cancer KRAS_G12C EPHA5 70 144 Sex:overall -1.06 -3.04 0.51 1430.81 1.00 2097 68 142 2 FALSE 0.61
non-small cell lung cancer KRAS_G12C EPHA5 457 260 Sex:overall 0.67 0.12 1.19 1465.62 1.00 3058 403 206 54 FALSE 1.51
colorectal cancer KRAS_G12C AR 41 59 Female -5.05 -12.29 -0.94 1163.27 1.00 957 41 59 0 TRUE 1.10
colorectal cancer KRAS_G12C AR 29 57 Male -5.11 -12.43 -0.82 1203.93 1.00 1153 29 57 0 TRUE 1.11
non-small cell lung cancer KRAS_G12C AR 286 81 Female 0.36 -0.19 0.89 1459.67 1.00 1804 271 66 15 TRUE 0.69
non-small cell lung cancer KRAS_G12C AR 172 29 Male 0.03 -1.09 0.87 1309.24 1.00 1352 169 26 3 TRUE 0.02
colorectal cancer KRAS_G12C AR 70 116 Sex:overall -5.03 -12.08 -0.82 1187.18 1.00 2110 70 116 0 TRUE 1.11
non-small cell lung cancer KRAS_G12C AR 458 110 Sex:overall 0.21 -1.13 1.29 1361.90 1.00 3156 440 92 18 TRUE 0.14
colorectal cancer KRAS_G12C GNAS 48 41 Female -5.00 -12.89 -0.80 145.91 1.03 1068 48 41 0 TRUE 0.96
colorectal cancer KRAS_G12C GNAS 33 34 Male -4.89 -12.90 -0.72 131.68 1.03 1296 33 34 0 TRUE 0.95
colorectal cancer KRAS_G12C GNAS 81 75 Sex:overall -4.82 -12.74 -0.83 124.03 1.03 2364 81 75 0 TRUE 0.97
colorectal cancer KRAS_G12C ASXL2 41 20 Female -1.68 -5.52 0.59 1302.13 1.00 990 41 20 0 FALSE 0.54
colorectal cancer KRAS_G12C ASXL2 29 51 Male -1.15 -4.04 0.84 1097.85 1.00 1174 28 50 1 FALSE 0.45
non-small cell lung cancer KRAS_G12C ASXL2 284 32 Female 0.60 -0.09 1.23 1238.79 1.00 1840 277 25 7 FALSE 1.10
non-small cell lung cancer KRAS_G12C ASXL2 172 31 Male 0.63 -0.15 1.34 1399.80 1.00 1354 166 25 6 FALSE 1.06
colorectal cancer KRAS_G12C ASXL2 70 71 Sex:overall -1.37 -4.59 1.14 1160.25 1.00 2164 69 70 1 FALSE 0.46
non-small cell lung cancer KRAS_G12C ASXL2 456 63 Sex:overall 0.63 -0.16 1.45 1301.08 1.00 3194 443 50 13 FALSE 0.80
colorectal cancer KRAS_G12C SF3B1 41 18 Female -5.07 -13.19 -0.20 426.41 1.00 993 41 18 0 TRUE 0.92
colorectal cancer KRAS_G12C SF3B1 29 52 Male -5.09 -12.70 -0.54 435.11 1.00 1167 29 52 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C SF3B1 285 55 Female -0.70 -1.67 0.14 1048.34 1.00 1816 280 50 5 TRUE 0.89
non-small cell lung cancer KRAS_G12C SF3B1 172 32 Male -0.91 -2.34 0.08 1281.78 1.00 1348 171 31 1 TRUE 0.87
colorectal cancer KRAS_G12C SF3B1 70 70 Sex:overall -4.95 -12.72 -0.23 428.60 1.00 2160 70 70 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C SF3B1 457 87 Sex:overall -0.79 -2.00 0.17 1189.90 1.00 3164 451 81 6 TRUE 0.76
colorectal cancer KRAS_G12C MLH1 48 20 Female -4.65 -12.94 -0.25 241.25 1.02 1089 48 20 0 TRUE 0.81
colorectal cancer KRAS_G12C MLH1 33 36 Male -4.60 -12.87 -0.27 228.92 1.02 1298 33 36 0 TRUE 0.78
colorectal cancer KRAS_G12C MLH1 81 56 Sex:overall -4.53 -12.54 -0.26 223.75 1.02 2387 81 56 0 TRUE 0.80
colorectal cancer KRAS_G12C ROS1 41 32 Female -1.99 -5.58 0.32 1443.06 1.00 979 41 32 0 TRUE 0.66
colorectal cancer KRAS_G12C ROS1 29 71 Male -1.46 -4.41 0.48 1310.40 1.00 1155 28 70 1 TRUE 0.62
non-small cell lung cancer KRAS_G12C ROS1 283 57 Female -0.57 -1.38 0.19 1300.56 1.00 1813 279 53 4 TRUE 0.84
non-small cell lung cancer KRAS_G12C ROS1 173 54 Male -0.44 -1.26 0.33 1472.50 1.00 1331 168 49 5 TRUE 0.56
colorectal cancer KRAS_G12C ROS1 70 103 Sex:overall -1.67 -4.81 0.64 1262.64 1.00 2134 69 102 1 TRUE 0.63
non-small cell lung cancer KRAS_G12C ROS1 456 111 Sex:overall -0.52 -1.45 0.31 1391.04 1.00 3144 447 102 9 TRUE 0.57
colorectal cancer KRAS_G12C PIK3R2 41 24 Female -4.63 -12.27 -0.24 1339.69 1.00 988 41 24 0 FALSE 0.86
colorectal cancer KRAS_G12C PIK3R2 29 28 Male -4.61 -12.36 -0.05 1319.27 1.00 1177 29 28 0 FALSE 0.86
colorectal cancer KRAS_G12C PIK3R2 70 52 Sex:overall -4.54 -11.68 -0.09 1313.51 1.00 2165 70 52 0 FALSE 0.86
colorectal cancer KRAS_G12C FLT3 48 19 Female -4.98 -11.78 -0.27 365.69 1.01 1086 48 19 0 TRUE 0.92
colorectal cancer KRAS_G12C FLT3 33 33 Male -4.97 -11.90 -0.12 377.07 1.01 1305 33 33 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C FLT3 293 42 Female 0.92 0.19 1.58 1168.14 1.00 1894 280 29 13 TRUE 1.93
non-small cell lung cancer KRAS_G12C FLT3 179 39 Male -0.94 -3.07 0.42 1410.48 1.00 1393 178 38 1 TRUE 0.52
colorectal cancer KRAS_G12C FLT3 81 52 Sex:overall -4.88 -11.70 -0.20 346.58 1.00 2391 81 52 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C FLT3 472 81 Sex:overall -0.01 -2.27 1.86 1411.14 1.00 3287 458 67 14 TRUE 0.00
colorectal cancer KRAS_G12C MSH2 41 34 Female -1.27 -4.13 0.54 588.70 1.00 985 40 33 1 TRUE 0.55
colorectal cancer KRAS_G12C MSH2 29 49 Male -1.67 -5.10 0.41 391.47 1.00 1168 29 49 0 TRUE 0.56
non-small cell lung cancer KRAS_G12C MSH2 283 26 Female -0.24 -1.38 0.83 1245.09 1.00 1842 279 22 4 TRUE 0.18
non-small cell lung cancer KRAS_G12C MSH2 172 30 Male -0.72 -2.39 0.40 1330.73 1.00 1353 171 29 1 TRUE 0.51
colorectal cancer KRAS_G12C MSH2 70 83 Sex:overall -1.43 -4.42 0.59 629.06 1.00 2153 69 82 1 TRUE 0.56
non-small cell lung cancer KRAS_G12C MSH2 455 56 Sex:overall -0.48 -2.08 0.80 1442.45 1.00 3195 450 51 5 TRUE 0.30
non-small cell lung cancer KRAS_G12C DIS3 283 29 Female 0.43 -0.48 1.12 1373.12 1.00 1840 278 24 5 FALSE 0.55
non-small cell lung cancer KRAS_G12C DIS3 172 36 Male 0.70 -0.11 1.42 1466.38 1.00 1352 164 28 8 FALSE 1.14
non-small cell lung cancer KRAS_G12C DIS3 455 65 Sex:overall 0.57 -0.52 1.64 1401.25 1.00 3192 442 52 13 FALSE 0.53
colorectal cancer KRAS_G12C AXL 41 30 Female -1.77 -5.40 0.27 1344.79 1.00 981 41 30 0 FALSE 0.61
colorectal cancer KRAS_G12C AXL 29 58 Male -1.28 -4.05 0.60 1342.03 1.00 1160 28 57 1 FALSE 0.56
colorectal cancer KRAS_G12C AXL 70 88 Sex:overall -1.51 -4.65 0.56 1307.72 1.00 2141 69 87 1 FALSE 0.60
colorectal cancer KRAS_G12C PIK3CG 41 39 Female -5.25 -11.75 -0.84 467.01 1.00 972 41 39 0 FALSE 1.10
colorectal cancer KRAS_G12C PIK3CG 29 68 Male -5.27 -11.90 -0.85 480.40 1.00 1149 29 68 0 FALSE 1.11
non-small cell lung cancer KRAS_G12C PIK3CG 283 88 Female 0.34 -0.16 0.82 1362.17 1.00 1797 267 72 16 FALSE 0.77
non-small cell lung cancer KRAS_G12C PIK3CG 175 92 Male 0.31 -0.19 0.78 1560.00 1.00 1310 162 79 13 FALSE 0.66
colorectal cancer KRAS_G12C PIK3CG 70 107 Sex:overall -5.14 -11.49 -0.60 422.05 1.00 2121 70 107 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C PIK3CG 458 180 Sex:overall 0.33 -0.43 1.02 1444.90 1.00 3107 429 151 29 FALSE 0.37
colorectal cancer KRAS_G12C MAP2K4 41 28 Female -1.44 -4.88 0.60 1176.27 1.00 982 41 28 0 TRUE 0.51
colorectal cancer KRAS_G12C MAP2K4 29 35 Male -1.02 -3.81 0.99 1243.21 1.00 1172 28 34 1 TRUE 0.39
colorectal cancer KRAS_G12C MAP2K4 70 63 Sex:overall -1.20 -4.24 1.04 1107.19 1.00 2154 69 62 1 TRUE 0.45
colorectal cancer KRAS_G12C EGFR 48 28 Female -4.70 -11.71 -0.50 840.27 1.00 1079 48 28 0 TRUE 0.92
colorectal cancer KRAS_G12C EGFR 33 38 Male -4.70 -12.31 -0.42 950.89 1.00 1296 33 38 0 TRUE 0.89
non-small cell lung cancer KRAS_G12C EGFR 292 724 Female -3.14 -3.92 -2.48 1507.61 1.00 1340 285 717 7 TRUE 16.86
non-small cell lung cancer KRAS_G12C EGFR 179 318 Male -3.23 -4.47 -2.22 1598.77 1.00 1164 177 316 2 TRUE 8.20
colorectal cancer KRAS_G12C EGFR 81 66 Sex:overall -4.60 -11.66 -0.44 1051.33 1.00 2375 81 66 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C EGFR 471 1042 Sex:overall -3.14 -4.43 -1.80 1562.85 1.00 2504 462 1033 9 TRUE 5.48
colorectal cancer KRAS_G12C ARID1B 41 70 Female -5.38 -12.67 -1.16 1027.35 1.00 950 41 70 0 TRUE 1.17
colorectal cancer KRAS_G12C ARID1B 29 70 Male -5.34 -12.32 -1.18 778.72 1.00 1146 29 70 0 TRUE 1.19
non-small cell lung cancer KRAS_G12C ARID1B 284 68 Female 0.34 -0.29 0.89 1149.98 1.00 1812 270 54 14 TRUE 0.61
non-small cell lung cancer KRAS_G12C ARID1B 172 43 Male -0.25 -1.80 0.53 144.11 1.02 1340 170 41 2 TRUE 0.17
colorectal cancer KRAS_G12C ARID1B 70 140 Sex:overall -5.26 -12.26 -1.16 757.47 1.00 2096 70 140 0 TRUE 1.18
non-small cell lung cancer KRAS_G12C ARID1B 456 111 Sex:overall 0.03 -1.42 0.96 515.30 1.01 3152 440 95 16 TRUE 0.02
non-small cell lung cancer KRAS_G12C INSR 283 33 Female -0.69 -1.80 0.26 1005.21 1.00 1824 280 30 3 FALSE 0.69
non-small cell lung cancer KRAS_G12C INSR 172 22 Male -0.79 -2.19 0.24 1248.82 1.00 1353 171 21 1 FALSE 0.68
non-small cell lung cancer KRAS_G12C INSR 455 55 Sex:overall -0.73 -2.00 0.34 1105.01 1.00 3177 451 51 4 FALSE 0.63
non-small cell lung cancer KRAS_G12C NKX2-1 283 34 Female 0.20 -0.83 0.96 910.39 1.00 1837 279 30 4 TRUE 0.16
non-small cell lung cancer KRAS_G12C NKX2-1 175 41 Male 0.88 0.12 1.60 1499.65 1.00 1352 164 30 11 TRUE 1.76
non-small cell lung cancer KRAS_G12C NKX2-1 458 75 Sex:overall 0.56 -0.65 1.75 1238.08 1.00 3189 443 60 15 TRUE 0.44
colorectal cancer KRAS_G12C ARID5B 41 20 Female -4.34 -10.74 -0.50 56.36 1.04 990 41 20 0 FALSE 1.00
colorectal cancer KRAS_G12C ARID5B 29 48 Male -4.34 -11.11 -0.48 63.63 1.04 1169 29 48 0 FALSE 0.98
colorectal cancer KRAS_G12C ARID5B 70 68 Sex:overall -4.23 -10.41 -0.37 61.10 1.04 2159 70 68 0 FALSE 1.00
non-small cell lung cancer KRAS_G12C WT1 283 39 Female -0.40 -1.34 0.45 1112.09 1.00 1832 278 34 5 TRUE 0.41
non-small cell lung cancer KRAS_G12C WT1 172 31 Male -0.65 -1.95 0.29 1069.01 1.00 1350 171 30 1 TRUE 0.58
non-small cell lung cancer KRAS_G12C WT1 455 70 Sex:overall -0.50 -1.74 0.58 1407.75 1.00 3182 449 64 6 TRUE 0.40
non-small cell lung cancer KRAS_G12C MET 292 94 Female -1.15 -2.01 -0.46 1238.97 1.00 1841 288 90 4 TRUE 2.24
non-small cell lung cancer KRAS_G12C MET 179 71 Male -1.05 -1.97 -0.27 1085.52 1.00 1368 175 67 4 TRUE 1.83
non-small cell lung cancer KRAS_G12C MET 471 165 Sex:overall -1.09 -2.06 -0.26 1312.92 1.00 3209 463 157 8 TRUE 1.65
non-small cell lung cancer KRAS_G12C PMS1 283 29 Female 0.17 -0.77 0.93 1243.60 1.00 1840 279 25 4 TRUE 0.16
non-small cell lung cancer KRAS_G12C PMS1 172 23 Male 0.27 -0.63 1.07 1131.14 1.00 1359 168 19 4 TRUE 0.27
non-small cell lung cancer KRAS_G12C PMS1 455 52 Sex:overall 0.22 -0.85 1.10 1349.02 1.00 3199 447 44 8 TRUE 0.18
non-small cell lung cancer KRAS_G12C PIK3C3 283 40 Female -0.41 -1.26 0.42 1168.81 1.00 1818 279 36 4 FALSE 0.47
non-small cell lung cancer KRAS_G12C PIK3C3 172 36 Male -0.40 -1.34 0.42 1223.67 1.00 1340 169 33 3 FALSE 0.43
non-small cell lung cancer KRAS_G12C PIK3C3 455 76 Sex:overall -0.40 -1.37 0.53 1283.13 1.00 3158 448 69 7 FALSE 0.37
colorectal cancer KRAS_G12C BRAF 48 128 Female -5.74 -12.42 -1.81 1049.44 1.00 983 48 128 0 TRUE 1.47
colorectal cancer KRAS_G12C BRAF 33 125 Male -5.69 -12.23 -1.68 1034.36 1.00 1211 33 125 0 TRUE 1.44
non-small cell lung cancer KRAS_G12C BRAF 292 113 Female -1.26 -2.07 -0.56 898.27 1.00 1815 287 108 5 TRUE 3.04
non-small cell lung cancer KRAS_G12C BRAF 179 80 Male -1.26 -2.06 -0.49 1087.16 1.00 1354 176 77 3 TRUE 2.68
colorectal cancer KRAS_G12C BRAF 81 253 Sex:overall -5.64 -11.92 -1.70 1046.19 1.00 2194 81 253 0 TRUE 1.46
non-small cell lung cancer KRAS_G12C BRAF 471 193 Sex:overall -1.26 -2.19 -0.44 898.78 1.00 3169 463 185 8 TRUE 2.32
colorectal cancer KRAS_G12C B2M 38 69 Female -1.38 -5.20 0.32 935.96 1.00 938 38 69 0 FALSE 0.46
colorectal cancer KRAS_G12C B2M 29 70 Male -0.15 -1.70 1.21 327.56 1.01 1129 26 67 3 FALSE 0.08
colorectal cancer KRAS_G12C B2M 67 139 Sex:overall -0.74 -3.41 1.01 1093.51 1.00 2067 64 136 3 FALSE 0.30
colorectal cancer KRAS_G12C TGFBR1 38 14 Female -0.63 -3.53 1.51 1471.61 1.00 967 37 13 1 FALSE 0.20
colorectal cancer KRAS_G12C TGFBR1 28 37 Male -1.50 -5.66 0.91 1183.00 1.00 1142 28 37 0 FALSE 0.44
non-small cell lung cancer KRAS_G12C TGFBR1 283 36 Female 0.68 -0.12 1.42 1269.39 1.00 1825 274 27 9 FALSE 1.13
non-small cell lung cancer KRAS_G12C TGFBR1 172 15 Male 0.41 -0.77 1.31 1400.77 1.00 1360 170 13 2 FALSE 0.36
colorectal cancer KRAS_G12C TGFBR1 66 51 Sex:overall -1.03 -4.49 1.39 1289.29 1.00 2109 65 50 1 FALSE 0.32
non-small cell lung cancer KRAS_G12C TGFBR1 455 51 Sex:overall 0.55 -0.59 1.59 1436.04 1.00 3185 444 40 11 FALSE 0.45
colorectal cancer KRAS_G12C TET2 41 31 Female -5.16 -11.92 -0.75 1140.87 1.00 983 41 31 0 TRUE 1.09
colorectal cancer KRAS_G12C TET2 29 60 Male -5.14 -12.15 -0.86 1145.59 1.00 1157 29 60 0 TRUE 1.06
non-small cell lung cancer KRAS_G12C TET2 283 38 Female -1.07 -2.74 -0.01 564.81 1.00 1828 282 37 1 TRUE 0.90
non-small cell lung cancer KRAS_G12C TET2 172 43 Male -0.42 -1.75 0.51 249.81 1.01 1344 167 38 5 TRUE 0.36
colorectal cancer KRAS_G12C TET2 70 91 Sex:overall -5.03 -11.86 -0.71 1163.03 1.00 2140 70 91 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C TET2 455 81 Sex:overall -0.73 -2.20 0.64 606.21 1.00 3172 449 75 6 TRUE 0.52
colorectal cancer KRAS_G12C PDGFRB 41 24 Female -0.82 -3.58 1.06 1085.48 1.00 986 40 23 1 TRUE 0.32
colorectal cancer KRAS_G12C PDGFRB 29 28 Male -1.16 -4.62 0.96 727.72 1.00 1177 29 28 0 TRUE 0.37
non-small cell lung cancer KRAS_G12C PDGFRB 286 54 Female 0.38 -0.24 0.95 1351.75 1.00 1823 276 44 10 TRUE 0.67
non-small cell lung cancer KRAS_G12C PDGFRB 172 38 Male 0.37 -0.32 1.00 1362.02 1.00 1349 166 32 6 TRUE 0.57
colorectal cancer KRAS_G12C PDGFRB 70 52 Sex:overall -0.96 -4.08 1.11 1009.29 1.00 2163 69 51 1 TRUE 0.34
non-small cell lung cancer KRAS_G12C PDGFRB 458 92 Sex:overall 0.38 -0.37 1.11 1415.73 1.00 3172 442 76 16 TRUE 0.44
colorectal cancer KRAS_G12C CARD11 41 49 Female -0.08 -1.42 1.05 1377.29 1.00 964 39 47 2 FALSE 0.04
colorectal cancer KRAS_G12C CARD11 29 79 Male -0.06 -1.29 1.04 1500.35 1.00 1138 27 77 2 FALSE 0.03
non-small cell lung cancer KRAS_G12C CARD11 284 71 Female 0.47 -0.08 0.98 1400.83 1.00 1810 269 56 15 FALSE 1.09
non-small cell lung cancer KRAS_G12C CARD11 172 59 Male 0.37 -0.26 0.92 1275.66 1.00 1331 164 51 8 FALSE 0.67
colorectal cancer KRAS_G12C CARD11 70 128 Sex:overall -0.06 -1.49 1.27 1453.22 1.00 2102 66 124 4 FALSE 0.03
non-small cell lung cancer KRAS_G12C CARD11 456 130 Sex:overall 0.41 -0.33 1.13 1343.28 1.00 3141 433 107 23 FALSE 0.51
colorectal cancer KRAS_G12C DNMT3A 41 24 Female -4.69 -11.32 -0.23 1209.09 1.00 989 41 24 0 TRUE 0.97
colorectal cancer KRAS_G12C DNMT3A 29 32 Male -4.69 -11.27 -0.23 1217.50 1.00 1175 29 32 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C DNMT3A 283 49 Female 0.70 0.03 1.35 1233.63 1.00 1829 270 36 13 TRUE 1.53
non-small cell lung cancer KRAS_G12C DNMT3A 172 28 Male 0.38 -0.65 1.12 1211.66 1.00 1353 169 25 3 TRUE 0.41
colorectal cancer KRAS_G12C DNMT3A 70 56 Sex:overall -4.65 -11.25 -0.31 956.06 1.00 2164 70 56 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C DNMT3A 455 77 Sex:overall 0.54 -0.48 1.34 1426.92 1.00 3182 439 61 16 TRUE 0.56
colorectal cancer KRAS_G12C MSH6 41 43 Female -5.12 -11.38 -0.85 610.43 1.00 971 41 43 0 TRUE 1.07
colorectal cancer KRAS_G12C MSH6 29 57 Male -5.11 -11.48 -0.83 657.32 1.00 1161 29 57 0 TRUE 1.07
colorectal cancer KRAS_G12C MSH6 70 100 Sex:overall -5.06 -11.25 -0.73 603.72 1.00 2132 70 100 0 TRUE 1.09
non-small cell lung cancer KRAS_G12C MAX 284 35 Female 0.74 -0.02 1.41 704.69 1.00 1824 277 28 7 FALSE 1.35
non-small cell lung cancer KRAS_G12C MAX 172 20 Male 1.05 0.24 1.89 1235.03 1.00 1360 165 13 7 FALSE 1.94
non-small cell lung cancer KRAS_G12C MAX 456 55 Sex:overall 0.86 -0.15 1.84 1391.54 1.00 3184 442 41 14 FALSE 0.99
non-small cell lung cancer KRAS_G12C INPP4B 283 60 Female 0.63 0.08 1.14 1539.87 1.00 1820 270 47 13 FALSE 1.68
non-small cell lung cancer KRAS_G12C INPP4B 174 66 Male 0.74 0.22 1.26 1491.38 1.00 1332 160 52 14 FALSE 2.17
non-small cell lung cancer KRAS_G12C INPP4B 457 126 Sex:overall 0.68 -0.10 1.45 1307.07 1.00 3152 430 99 27 FALSE 1.09
non-small cell lung cancer KRAS_G12C NFE2L2 284 52 Female -0.20 -1.02 0.58 1562.39 1.00 1822 277 45 7 FALSE 0.22
non-small cell lung cancer KRAS_G12C NFE2L2 172 72 Male -0.64 -1.56 0.15 1471.86 1.00 1319 168 68 4 FALSE 0.81
non-small cell lung cancer KRAS_G12C NFE2L2 456 124 Sex:overall -0.40 -1.54 1.07 1480.72 1.00 3141 445 113 11 FALSE 0.28
colorectal cancer KRAS_G12C SOX9 41 125 Female -0.06 -0.98 0.71 1134.05 1.00 899 37 121 4 FALSE 0.05
colorectal cancer KRAS_G12C SOX9 31 139 Male 0.10 -0.76 0.93 1158.01 1.00 1082 26 134 5 FALSE 0.08
colorectal cancer KRAS_G12C SOX9 72 264 Sex:overall 0.03 -0.95 1.04 1292.77 1.00 1981 63 255 9 FALSE 0.02
colorectal cancer KRAS_G12C ETV1 38 23 Female -4.72 -11.38 -0.29 168.79 1.01 957 38 23 0 TRUE 0.91
colorectal cancer KRAS_G12C ETV1 28 29 Male -4.68 -11.42 -0.25 182.59 1.01 1147 28 29 0 TRUE 0.89
colorectal cancer KRAS_G12C ETV1 66 52 Sex:overall -4.64 -11.29 -0.14 177.44 1.01 2104 66 52 0 TRUE 0.90
colorectal cancer KRAS_G12C ARAF 41 30 Female -0.95 -3.88 0.95 1243.55 1.00 984 40 29 1 FALSE 0.35
colorectal cancer KRAS_G12C ARAF 29 25 Male -1.33 -4.99 0.85 1340.77 1.00 1181 29 25 0 FALSE 0.41
non-small cell lung cancer KRAS_G12C ARAF 284 55 Female 0.04 -0.76 0.76 1449.23 1.00 1825 276 47 8 FALSE 0.04
non-small cell lung cancer KRAS_G12C ARAF 172 14 Male -0.39 -2.11 0.85 1481.96 1.00 1365 171 13 1 FALSE 0.21
colorectal cancer KRAS_G12C ARAF 70 55 Sex:overall -1.13 -4.42 1.11 1210.02 1.00 2165 69 54 1 FALSE 0.38
non-small cell lung cancer KRAS_G12C ARAF 456 69 Sex:overall -0.15 -1.71 1.53 1409.37 1.00 3190 447 60 9 FALSE 0.07
non-small cell lung cancer KRAS_G12C JAK2 292 33 Female -0.11 -1.03 0.76 1472.43 1.00 1894 287 28 5 TRUE 0.09
non-small cell lung cancer KRAS_G12C JAK2 179 45 Male -0.43 -1.53 0.48 1372.95 1.00 1390 176 42 3 TRUE 0.41
non-small cell lung cancer KRAS_G12C JAK2 471 78 Sex:overall -0.29 -1.63 0.90 1377.11 1.00 3284 463 70 8 TRUE 0.19
colorectal cancer KRAS_G12C SMAD2 41 43 Female 0.72 -0.37 1.67 1510.51 1.00 974 37 39 4 TRUE 0.77
colorectal cancer KRAS_G12C SMAD2 29 59 Male 0.51 -0.78 1.54 1472.04 1.00 1155 27 57 2 TRUE 0.41
colorectal cancer KRAS_G12C SMAD2 70 102 Sex:overall 0.61 -0.77 1.80 1433.58 1.00 2129 64 96 6 TRUE 0.45
non-small cell lung cancer KRAS_G12C TP63 283 34 Female -0.24 -1.18 0.69 941.65 1.00 1825 278 29 5 FALSE 0.21
non-small cell lung cancer KRAS_G12C TP63 172 38 Male -0.53 -1.64 0.42 958.42 1.00 1337 170 36 2 FALSE 0.51
non-small cell lung cancer KRAS_G12C TP63 455 72 Sex:overall -0.36 -1.56 0.74 1344.25 1.00 3162 448 65 7 FALSE 0.27
colorectal cancer KRAS_G12C JUN 38 32 Female -4.66 -12.27 -0.05 522.38 1.00 949 38 32 0 FALSE 0.83
colorectal cancer KRAS_G12C JUN 28 21 Male -4.68 -12.13 0.08 479.26 1.00 1154 28 21 0 FALSE 0.78
colorectal cancer KRAS_G12C JUN 66 53 Sex:overall -4.56 -11.82 0.07 503.79 1.00 2103 66 53 0 FALSE 0.82
colorectal cancer KRAS_G12C DNMT3B 38 25 Female -4.85 -12.25 -0.33 570.81 1.00 956 38 25 0 FALSE 0.96
colorectal cancer KRAS_G12C DNMT3B 28 39 Male -4.86 -12.38 -0.31 588.63 1.00 1140 28 39 0 FALSE 0.95
colorectal cancer KRAS_G12C DNMT3B 66 64 Sex:overall -4.79 -12.31 -0.36 561.90 1.00 2096 66 64 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C MYOD1 283 29 Female -0.16 -1.19 0.69 810.97 1.00 1830 280 26 3 FALSE 0.13
non-small cell lung cancer KRAS_G12C MYOD1 172 29 Male -0.01 -1.04 0.84 1266.95 1.00 1348 168 25 4 FALSE 0.01
non-small cell lung cancer KRAS_G12C MYOD1 455 58 Sex:overall -0.09 -1.15 0.85 1284.06 1.00 3178 448 51 7 FALSE 0.06
colorectal cancer KRAS_G12C FGFR1 48 21 Female -4.64 -11.90 -0.28 1381.20 1.00 1084 48 21 0 TRUE 0.92
colorectal cancer KRAS_G12C FGFR1 33 30 Male -4.62 -11.62 -0.16 1392.94 1.00 1305 33 30 0 TRUE 0.93
colorectal cancer KRAS_G12C FGFR1 81 51 Sex:overall -4.53 -11.44 -0.08 1331.02 1.00 2389 81 51 0 TRUE 0.92
colorectal cancer KRAS_G12C MITF 41 22 Female 0.58 -0.80 1.80 1260.36 1.01 989 39 20 2 FALSE 0.41
colorectal cancer KRAS_G12C MITF 29 30 Male 0.40 -1.24 1.62 1077.56 1.00 1176 28 29 1 FALSE 0.24
colorectal cancer KRAS_G12C MITF 70 52 Sex:overall 0.47 -1.17 1.83 1183.63 1.00 2165 67 49 3 FALSE 0.25
non-small cell lung cancer KRAS_G12C BTK 283 47 Female 0.35 -0.44 1.03 1446.72 1.00 1827 274 38 9 TRUE 0.46
non-small cell lung cancer KRAS_G12C BTK 172 13 Male -0.18 -1.84 1.00 1471.30 1.00 1366 171 12 1 TRUE 0.09
non-small cell lung cancer KRAS_G12C BTK 455 60 Sex:overall 0.07 -1.66 1.41 1467.68 1.00 3193 445 50 10 TRUE 0.03
colorectal cancer KRAS_G12C SH2B3 37 18 Female -4.87 -12.38 -0.29 1142.55 1.00 901 37 18 0 FALSE 0.92
colorectal cancer KRAS_G12C SH2B3 26 38 Male -4.82 -12.19 -0.30 1167.55 1.00 1073 26 38 0 FALSE 0.93
colorectal cancer KRAS_G12C SH2B3 63 56 Sex:overall -4.73 -11.99 -0.06 1104.74 1.00 1974 63 56 0 FALSE 0.92
colorectal cancer KRAS_G12C GLI1 37 32 Female -5.10 -12.87 -0.70 1147.77 1.00 889 37 32 0 FALSE 1.03
colorectal cancer KRAS_G12C GLI1 26 55 Male -5.11 -13.05 -0.80 978.04 1.00 1057 26 55 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C GLI1 262 56 Female 0.61 0.04 1.13 1296.68 1.00 1641 249 43 13 FALSE 1.61
non-small cell lung cancer KRAS_G12C GLI1 160 50 Male 0.59 -0.02 1.14 1296.85 1.00 1194 151 41 9 FALSE 1.31
colorectal cancer KRAS_G12C GLI1 63 87 Sex:overall -5.02 -12.47 -0.76 909.16 1.00 1946 63 87 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C GLI1 422 106 Sex:overall 0.58 -0.08 1.18 1411.72 1.00 2835 400 84 22 FALSE 1.04
colorectal cancer KRAS_G12C ZFHX3 37 96 Female -2.69 -6.38 -0.71 572.27 1.01 849 37 96 0 FALSE 1.18
colorectal cancer KRAS_G12C ZFHX3 26 130 Male -2.26 -5.29 -0.34 990.88 1.00 1018 25 129 1 FALSE 1.22
non-small cell lung cancer KRAS_G12C ZFHX3 262 90 Female -0.04 -0.60 0.47 1111.53 1.00 1610 248 76 14 FALSE 0.06
non-small cell lung cancer KRAS_G12C ZFHX3 159 74 Male -0.28 -1.09 0.33 1412.34 1.00 1164 154 69 5 FALSE 0.37
colorectal cancer KRAS_G12C ZFHX3 63 226 Sex:overall -2.43 -5.54 -0.31 1014.91 1.00 1867 62 225 1 FALSE 1.18
non-small cell lung cancer KRAS_G12C ZFHX3 421 164 Sex:overall -0.16 -0.99 0.53 1415.06 1.00 2774 402 145 19 FALSE 0.16
colorectal cancer KRAS_G12C MST1R 34 28 Female -4.72 -12.09 -0.17 266.46 1.01 867 34 28 0 FALSE 0.89
colorectal cancer KRAS_G12C MST1R 25 45 Male -4.73 -11.99 -0.31 226.71 1.01 1036 25 45 0 FALSE 0.92
colorectal cancer KRAS_G12C MST1R 59 73 Sex:overall -4.65 -12.00 -0.10 210.44 1.02 1903 59 73 0 FALSE 0.89
colorectal cancer KRAS_G12C MGA 37 50 Female -0.94 -2.96 0.52 1402.87 1.00 875 36 49 1 FALSE 0.55
colorectal cancer KRAS_G12C MGA 26 73 Male -0.91 -2.95 0.62 1272.72 1.00 1044 25 72 1 FALSE 0.50
non-small cell lung cancer KRAS_G12C MGA 264 117 Female 0.56 0.18 0.93 1324.15 1.00 1611 238 91 26 FALSE 2.33
non-small cell lung cancer KRAS_G12C MGA 160 80 Male 0.46 -0.07 0.90 1250.83 1.00 1163 148 68 12 FALSE 1.29
colorectal cancer KRAS_G12C MGA 63 123 Sex:overall -0.94 -3.08 0.73 1332.24 1.00 1919 61 121 2 FALSE 0.48
non-small cell lung cancer KRAS_G12C MGA 424 197 Sex:overall 0.52 0.01 1.04 1170.29 1.00 2774 386 159 38 FALSE 1.08
colorectal cancer KRAS_G12C TCF3 34 31 Female -4.87 -11.18 -0.55 211.18 1.02 862 34 31 0 FALSE 0.97
colorectal cancer KRAS_G12C TCF3 25 37 Male -4.89 -11.27 -0.60 222.46 1.02 1039 25 37 0 FALSE 0.96
colorectal cancer KRAS_G12C TCF3 59 68 Sex:overall -4.81 -10.98 -0.55 188.03 1.02 1901 59 68 0 FALSE 0.97
non-small cell lung cancer KRAS_G12C KMT2B 148 33 Female 0.32 -0.48 1.08 1280.68 1.00 952 141 26 7 FALSE 0.36
non-small cell lung cancer KRAS_G12C KMT2B 90 38 Male 0.07 -0.86 0.88 1330.64 1.00 650 86 34 4 FALSE 0.06
non-small cell lung cancer KRAS_G12C KMT2B 238 71 Sex:overall 0.18 -0.85 1.21 1426.99 1.00 1602 227 60 11 FALSE 0.14
colorectal cancer KRAS_G12C TCF7L2 37 124 Female -0.10 -1.08 0.70 1099.55 1.00 808 33 120 4 FALSE 0.09
colorectal cancer KRAS_G12C TCF7L2 26 175 Male 0.03 -0.82 0.85 968.89 1.00 953 21 170 5 FALSE 0.02
colorectal cancer KRAS_G12C TCF7L2 63 299 Sex:overall -0.05 -1.17 0.97 1130.10 1.00 1761 54 290 9 FALSE 0.03
colorectal cancer KRAS_G12C ANKRD11 34 56 Female -5.39 -12.67 -1.07 925.88 1.01 842 34 56 0 FALSE 1.14
colorectal cancer KRAS_G12C ANKRD11 25 90 Male -5.42 -12.76 -1.11 726.07 1.01 1010 25 90 0 FALSE 1.16
non-small cell lung cancer KRAS_G12C ANKRD11 261 40 Female -0.09 -1.11 0.71 549.80 1.01 1642 254 33 7 FALSE 0.07
non-small cell lung cancer KRAS_G12C ANKRD11 159 32 Male -0.55 -2.14 0.43 900.28 1.00 1195 158 31 1 FALSE 0.40
colorectal cancer KRAS_G12C ANKRD11 59 146 Sex:overall -5.32 -12.23 -1.07 844.76 1.01 1852 59 146 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C ANKRD11 420 72 Sex:overall -0.32 -1.73 0.77 1083.40 1.01 2837 412 64 8 FALSE 0.21
colorectal cancer KRAS_G12C PGR 34 30 Female -4.97 -12.47 -0.29 262.57 1.00 859 34 30 0 FALSE 0.92
colorectal cancer KRAS_G12C PGR 25 33 Male -4.93 -12.51 -0.18 260.30 1.01 1047 25 33 0 FALSE 0.88
non-small cell lung cancer KRAS_G12C PGR 261 44 Female 0.75 0.12 1.30 150.63 1.03 1640 249 32 12 FALSE 1.89
non-small cell lung cancer KRAS_G12C PGR 160 43 Male 0.61 -0.14 1.16 54.37 1.06 1191 153 36 7 FALSE 1.14
colorectal cancer KRAS_G12C PGR 59 63 Sex:overall -4.87 -12.38 -0.13 264.68 1.01 1906 59 63 0 FALSE 0.90
non-small cell lung cancer KRAS_G12C PGR 421 87 Sex:overall 0.67 -0.13 1.35 131.17 1.03 2831 402 68 19 FALSE 1.04
colorectal cancer KRAS_G12C PLCG2 34 31 Female -0.46 -2.49 1.04 901.83 1.00 860 33 30 1 FALSE 0.21
colorectal cancer KRAS_G12C PLCG2 25 54 Male -0.50 -2.58 0.95 1099.48 1.00 1028 24 53 1 FALSE 0.23
non-small cell lung cancer KRAS_G12C PLCG2 261 31 Female 0.23 -0.73 1.13 1272.23 1.00 1651 254 24 7 FALSE 0.21
non-small cell lung cancer KRAS_G12C PLCG2 159 31 Male -0.53 -2.25 0.59 1110.37 1.00 1199 158 30 1 FALSE 0.33
colorectal cancer KRAS_G12C PLCG2 59 85 Sex:overall -0.48 -2.61 1.12 1209.32 1.00 1888 57 83 2 FALSE 0.21
non-small cell lung cancer KRAS_G12C PLCG2 420 62 Sex:overall -0.16 -1.96 1.13 1618.81 1.00 2850 412 54 8 FALSE 0.08
colorectal cancer KRAS_G12C POLD1 37 49 Female -1.75 -4.89 0.10 71.45 1.05 880 37 49 0 TRUE 0.72
colorectal cancer KRAS_G12C POLD1 26 63 Male -1.40 -3.95 0.33 103.25 1.04 1060 25 62 1 TRUE 0.66
non-small cell lung cancer KRAS_G12C POLD1 261 31 Female -0.23 -1.35 0.79 1139.28 1.00 1658 256 26 5 TRUE 0.17
non-small cell lung cancer KRAS_G12C POLD1 159 27 Male -1.39 -5.37 0.27 1173.85 1.00 1204 159 27 0 TRUE 0.46
colorectal cancer KRAS_G12C POLD1 63 112 Sex:overall -1.56 -4.25 0.24 86.70 1.04 1940 62 111 1 TRUE 0.70
non-small cell lung cancer KRAS_G12C POLD1 420 58 Sex:overall -0.77 -3.36 0.80 1327.48 1.00 2862 415 53 5 TRUE 0.36
colorectal cancer KRAS_G12C INHBA 37 24 Female -1.30 -4.68 0.87 1070.11 1.00 895 37 24 0 FALSE 0.42
colorectal cancer KRAS_G12C INHBA 26 30 Male -0.84 -3.58 1.19 930.80 1.00 1077 25 29 1 FALSE 0.30
non-small cell lung cancer KRAS_G12C INHBA 261 46 Female 0.29 -0.35 0.92 1313.02 1.00 1650 252 37 9 FALSE 0.44
non-small cell lung cancer KRAS_G12C INHBA 159 41 Male 0.19 -0.57 0.81 862.35 1.00 1197 154 36 5 FALSE 0.23
colorectal cancer KRAS_G12C INHBA 63 54 Sex:overall -1.05 -4.12 1.20 1056.59 1.00 1972 62 53 1 FALSE 0.35
non-small cell lung cancer KRAS_G12C INHBA 420 87 Sex:overall 0.24 -0.56 0.94 1415.15 1.00 2847 406 73 14 FALSE 0.27
non-small cell lung cancer KRAS_G12C PREX2 148 62 Female 0.45 -0.11 0.98 1373.24 1.00 932 136 50 12 FALSE 0.98
non-small cell lung cancer KRAS_G12C PREX2 91 43 Male 0.43 -0.20 1.00 1223.17 1.00 649 84 36 7 FALSE 0.80
non-small cell lung cancer KRAS_G12C PREX2 239 105 Sex:overall 0.44 -0.22 1.08 1336.83 1.00 1581 220 86 19 FALSE 0.72
colorectal cancer KRAS_G12C AMER1 41 85 Female 0.10 -0.93 0.96 1357.51 1.00 936 37 81 4 FALSE 0.08
colorectal cancer KRAS_G12C AMER1 29 84 Male -0.01 -1.17 0.98 1271.13 1.00 1128 27 82 2 FALSE 0.00
non-small cell lung cancer KRAS_G12C AMER1 285 104 Female 0.86 0.41 1.29 1377.24 1.00 1802 258 77 27 FALSE 4.06
non-small cell lung cancer KRAS_G12C AMER1 172 45 Male 0.64 -0.03 1.25 1470.75 1.00 1345 164 37 8 FALSE 1.28
colorectal cancer KRAS_G12C AMER1 70 169 Sex:overall 0.03 -1.32 1.10 1516.42 1.00 2064 64 163 6 FALSE 0.02
non-small cell lung cancer KRAS_G12C AMER1 457 149 Sex:overall 0.75 -0.10 1.52 1380.49 1.00 3147 422 114 35 FALSE 1.15
colorectal cancer KRAS_G12C HLA-A 34 26 Female -4.17 -11.26 -0.31 79.46 1.05 866 34 26 0 FALSE 0.79
colorectal cancer KRAS_G12C HLA-A 25 25 Male -4.14 -11.13 -0.24 98.40 1.04 1053 25 25 0 FALSE 0.79
colorectal cancer KRAS_G12C HLA-A 59 51 Sex:overall -4.07 -10.93 -0.23 99.49 1.04 1919 59 51 0 FALSE 0.80
colorectal cancer KRAS_G12C EPHA7 37 39 Female -4.98 -11.58 -0.97 324.42 1.02 883 37 39 0 FALSE 1.15
colorectal cancer KRAS_G12C EPHA7 26 51 Male -4.99 -11.79 -0.72 577.65 1.02 1062 26 51 0 FALSE 1.14
non-small cell lung cancer KRAS_G12C EPHA7 261 67 Female 0.26 -0.32 0.81 1012.30 1.00 1631 248 54 13 FALSE 0.44
non-small cell lung cancer KRAS_G12C EPHA7 159 62 Male 0.01 -0.72 0.62 1167.40 1.00 1179 153 56 6 FALSE 0.01
colorectal cancer KRAS_G12C EPHA7 63 90 Sex:overall -4.90 -11.20 -0.74 405.99 1.02 1945 63 90 0 FALSE 1.15
non-small cell lung cancer KRAS_G12C EPHA7 420 129 Sex:overall 0.15 -0.70 0.92 1233.86 1.00 2810 401 110 19 FALSE 0.14
colorectal cancer KRAS_G12C NCOA3 37 21 Female -1.44 -4.93 0.78 1120.16 1.00 898 37 21 0 TRUE 0.49
colorectal cancer KRAS_G12C NCOA3 26 35 Male -0.94 -3.67 1.14 1134.98 1.00 1074 25 34 1 TRUE 0.36
colorectal cancer KRAS_G12C NCOA3 63 56 Sex:overall -1.15 -4.26 1.18 1131.58 1.00 1972 62 55 1 TRUE 0.41
non-small cell lung cancer KRAS_G12C DROSHA 148 26 Female 0.54 -0.49 1.47 1055.40 1.00 943 141 19 7 FALSE 0.55
non-small cell lung cancer KRAS_G12C DROSHA 90 28 Male -0.55 -2.60 0.86 625.01 1.00 652 89 27 1 FALSE 0.28
non-small cell lung cancer KRAS_G12C DROSHA 238 54 Sex:overall -0.02 -2.10 1.59 1183.23 1.00 1595 230 46 8 FALSE 0.01
cancer of unknown primary KRAS_G12D SPEN 36 26 Female 0.25 -1.16 1.44 844.71 1.00 368 32 22 4 FALSE 0.16
cancer of unknown primary KRAS_G12D SPEN 19 29 Male -0.96 -4.60 0.91 895.92 1.00 346 19 29 0 FALSE 0.29
colorectal cancer KRAS_G12D SPEN 144 55 Female -0.26 -1.04 0.36 1467.38 1.00 868 139 50 5 FALSE 0.31
colorectal cancer KRAS_G12D SPEN 159 100 Male 0.07 -0.50 0.63 1398.53 1.00 1019 144 85 15 FALSE 0.10
non-small cell lung cancer KRAS_G12D SPEN 104 56 Female -0.95 -2.73 0.46 1220.13 1.00 1996 102 54 2 FALSE 0.60
non-small cell lung cancer KRAS_G12D SPEN 48 65 Male -1.71 -4.73 0.16 1340.10 1.00 1462 48 65 0 FALSE 0.62
uterine cancer KRAS_G12D SPEN 57 120 Female 0.60 -0.18 1.26 1260.23 1.00 987 47 110 10 FALSE 0.98
cancer of unknown primary KRAS_G12D SPEN 55 55 Sex:overall -0.34 -2.93 1.41 1106.71 1.00 714 51 51 4 FALSE 0.12
colorectal cancer KRAS_G12D SPEN 303 155 Sex:overall -0.08 -0.98 0.80 1569.03 1.00 1887 283 135 20 FALSE 0.06
non-small cell lung cancer KRAS_G12D SPEN 152 121 Sex:overall -1.29 -3.60 0.53 1165.15 1.00 3458 150 119 2 FALSE 0.63
uterine cancer KRAS_G12D SPEN 57 120 Sex:overall 0.56 -3.91 4.99 1487.13 1.00 987 47 110 10 FALSE 0.11
colorectal cancer KRAS_G12D KMT2C 139 68 Female -0.37 -1.11 0.25 1359.18 1.00 828 133 62 6 FALSE 0.53
colorectal cancer KRAS_G12D KMT2C 156 130 Male -0.11 -0.63 0.44 1521.32 1.00 976 140 114 16 FALSE 0.16
non-small cell lung cancer KRAS_G12D KMT2C 104 113 Female -0.86 -2.15 0.15 1459.25 1.00 1929 102 111 2 FALSE 0.87
non-small cell lung cancer KRAS_G12D KMT2C 47 109 Male -0.53 -1.74 0.55 1413.42 1.00 1401 44 106 3 FALSE 0.45
colorectal cancer KRAS_G12D KMT2C 295 198 Sex:overall -0.24 -1.12 0.61 1449.82 1.00 1804 273 176 22 FALSE 0.22
non-small cell lung cancer KRAS_G12D KMT2C 151 222 Sex:overall -0.70 -2.18 0.50 1480.46 1.00 3330 146 217 5 FALSE 0.53
appendiceal cancer KRAS_G12D TP53 30 24 Female 0.42 -0.32 1.20 1424.36 1.00 49 21 15 9 TRUE 0.54
appendiceal cancer KRAS_G12D TP53 26 27 Male 0.53 -0.22 1.34 1378.99 1.00 41 15 16 11 TRUE 0.74
cancer of unknown primary KRAS_G12D TP53 36 223 Female 0.24 -0.36 0.91 1217.78 1.00 209 15 202 21 TRUE 0.35
cancer of unknown primary KRAS_G12D TP53 19 197 Male -0.20 -1.04 0.49 1304.32 1.00 204 12 190 7 TRUE 0.22
colorectal cancer KRAS_G12D TP53 168 796 Female -0.49 -0.74 -0.25 143.81 1.02 340 76 704 92 TRUE 3.56
colorectal cancer KRAS_G12D TP53 195 923 Male -0.48 -0.73 -0.22 140.00 1.02 417 87 815 108 TRUE 3.24
non-small cell lung cancer KRAS_G12D TP53 107 1120 Female -0.93 -1.33 -0.54 1352.01 1.00 1098 76 1089 31 TRUE 5.28
non-small cell lung cancer KRAS_G12D TP53 50 936 Male -1.08 -1.61 -0.59 1554.24 1.00 702 35 921 15 TRUE 4.56
pancreatic cancer KRAS_G12D TP53 249 449 Female 0.79 0.44 1.08 1126.34 1.00 234 77 277 172 TRUE 5.70
pancreatic cancer KRAS_G12D TP53 266 497 Male 1.05 0.75 1.39 888.10 1.00 280 60 291 206 TRUE 9.90
uterine cancer KRAS_G12D TP53 56 541 Female -1.19 -1.90 -0.56 672.35 1.00 687 45 530 11 TRUE 3.45
appendiceal cancer KRAS_G12D TP53 56 51 Sex:overall 0.48 -0.44 1.39 1542.64 1.00 90 36 31 20 TRUE 0.49
cancer of unknown primary KRAS_G12D TP53 55 420 Sex:overall 0.01 -1.01 0.92 1444.07 1.00 413 27 392 28 TRUE 0.01
colorectal cancer KRAS_G12D TP53 363 1719 Sex:overall -0.48 -0.78 -0.21 287.70 1.01 757 163 1519 200 TRUE 1.90
non-small cell lung cancer KRAS_G12D TP53 157 2056 Sex:overall -1.02 -1.82 -0.31 1414.49 1.00 1800 111 2010 46 TRUE 1.82
pancreatic cancer KRAS_G12D TP53 515 946 Sex:overall 0.92 0.26 1.48 1540.45 1.00 514 137 568 378 TRUE 2.40
uterine cancer KRAS_G12D TP53 56 541 Sex:overall -1.07 -4.99 3.56 1403.83 1.00 687 45 530 11 TRUE 0.24
colorectal cancer KRAS_G12D ATRX 144 73 Female -0.26 -0.96 0.39 1016.49 1.00 854 135 64 9 TRUE 0.33
colorectal cancer KRAS_G12D ATRX 158 46 Male -0.58 -1.60 0.22 1470.48 1.00 1041 155 43 3 TRUE 0.69
non-small cell lung cancer KRAS_G12D ATRX 104 162 Female 0.16 -0.58 0.78 1466.94 1.00 1917 94 152 10 TRUE 0.19
non-small cell lung cancer KRAS_G12D ATRX 48 46 Male -1.35 -5.89 0.56 1181.87 1.00 1458 48 46 0 TRUE 0.37
uterine cancer KRAS_G12D ATRX 53 176 Female -1.25 -2.57 -0.14 1468.90 1.00 963 50 173 3 TRUE 1.32
colorectal cancer KRAS_G12D ATRX 302 119 Sex:overall -0.41 -1.63 0.59 1479.64 1.00 1895 290 107 12 TRUE 0.33
non-small cell lung cancer KRAS_G12D ATRX 152 208 Sex:overall -0.54 -3.53 1.46 1186.91 1.00 3375 142 198 10 TRUE 0.18
uterine cancer KRAS_G12D ATRX 53 176 Sex:overall -1.04 -5.28 3.81 1408.62 1.00 963 50 173 3 TRUE 0.20
colorectal cancer KRAS_G12D ATR 144 30 Female -1.08 -2.83 0.09 1371.23 1.00 879 143 29 1 FALSE 0.83
colorectal cancer KRAS_G12D ATR 160 84 Male -0.23 -0.95 0.47 1277.26 1.00 1028 150 74 10 FALSE 0.28
non-small cell lung cancer KRAS_G12D ATR 104 69 Female -0.25 -1.51 0.79 1563.88 1.00 1981 100 65 4 FALSE 0.17
non-small cell lung cancer KRAS_G12D ATR 48 60 Male -1.12 -4.87 0.43 1132.85 1.00 1444 48 60 0 FALSE 0.39
uterine cancer KRAS_G12D ATR 54 98 Female -0.30 -1.49 0.72 1255.78 1.00 1001 50 94 4 FALSE 0.23
colorectal cancer KRAS_G12D ATR 304 114 Sex:overall -0.63 -2.40 0.95 1604.16 1.00 1907 293 103 11 FALSE 0.35
non-small cell lung cancer KRAS_G12D ATR 152 129 Sex:overall -0.68 -2.99 0.86 1095.30 1.00 3425 148 125 4 FALSE 0.30
uterine cancer KRAS_G12D ATR 54 98 Sex:overall -0.25 -4.59 4.12 1335.70 1.00 1001 50 94 4 FALSE 0.04
colorectal cancer KRAS_G12D PDGFRA 160 28 Female 0.08 -0.74 0.84 874.31 1.00 969 155 23 5 TRUE 0.08
colorectal cancer KRAS_G12D PDGFRA 183 32 Male 0.03 -0.81 0.80 909.00 1.01 1157 179 28 4 TRUE 0.03
non-small cell lung cancer KRAS_G12D PDGFRA 107 69 Female -1.08 -2.96 0.15 1533.32 1.00 2043 106 68 1 TRUE 0.79
non-small cell lung cancer KRAS_G12D PDGFRA 50 79 Male -0.76 -2.19 0.54 1582.26 1.00 1486 48 77 2 TRUE 0.55
colorectal cancer KRAS_G12D PDGFRA 343 60 Sex:overall 0.05 -0.82 0.90 917.96 1.01 2126 334 51 9 TRUE 0.04
non-small cell lung cancer KRAS_G12D PDGFRA 157 148 Sex:overall -0.91 -2.74 0.69 1576.82 1.00 3529 154 145 3 TRUE 0.56
colorectal cancer KRAS_G12D FBXW7 166 137 Female 0.28 -0.11 0.64 1755.54 1.00 889 143 114 23 TRUE 0.83
colorectal cancer KRAS_G12D FBXW7 190 202 Male 0.34 -0.02 0.70 1311.54 1.00 1034 154 166 36 TRUE 1.26
non-small cell lung cancer KRAS_G12D FBXW7 107 39 Female -0.85 -2.87 0.58 1535.83 1.00 2073 106 38 1 TRUE 0.48
non-small cell lung cancer KRAS_G12D FBXW7 50 47 Male -0.76 -2.67 0.80 1303.82 1.00 1514 49 46 1 TRUE 0.40
uterine cancer KRAS_G12D FBXW7 57 145 Female 0.72 0.07 1.36 1518.48 1.00 1048 45 133 12 TRUE 1.47
colorectal cancer KRAS_G12D FBXW7 356 339 Sex:overall 0.31 -0.20 0.79 1459.12 1.00 1923 297 280 59 TRUE 0.63
non-small cell lung cancer KRAS_G12D FBXW7 157 86 Sex:overall -0.79 -2.78 0.93 1354.15 1.00 3587 155 84 2 TRUE 0.37
uterine cancer KRAS_G12D FBXW7 57 145 Sex:overall 0.58 -3.98 4.85 1450.05 1.00 1048 45 133 12 TRUE 0.11
colorectal cancer KRAS_G12D MAP3K1 144 39 Female -0.38 -1.20 0.38 415.71 1.00 877 139 34 5 FALSE 0.46
colorectal cancer KRAS_G12D MAP3K1 158 53 Male -0.45 -1.25 0.27 423.12 1.01 1032 154 49 4 FALSE 0.59
non-small cell lung cancer KRAS_G12D MAP3K1 104 39 Female -0.67 -2.60 0.77 1224.57 1.00 2007 103 38 1 FALSE 0.37
non-small cell lung cancer KRAS_G12D MAP3K1 48 28 Male -0.54 -2.50 1.01 1442.34 1.00 1475 47 27 1 FALSE 0.26
uterine cancer KRAS_G12D MAP3K1 54 71 Female 0.10 -1.10 1.06 1604.15 1.00 1000 50 67 4 FALSE 0.06
colorectal cancer KRAS_G12D MAP3K1 302 92 Sex:overall -0.43 -1.32 0.35 521.56 1.00 1909 293 83 9 FALSE 0.48
non-small cell lung cancer KRAS_G12D MAP3K1 152 67 Sex:overall -0.59 -2.52 0.95 1236.63 1.00 3482 150 65 2 FALSE 0.29
uterine cancer KRAS_G12D MAP3K1 54 71 Sex:overall 0.21 -3.73 4.46 1643.95 1.00 1000 50 67 4 FALSE 0.04
colorectal cancer KRAS_G12D NSD1 144 35 Female -0.74 -2.00 0.20 102.15 1.04 880 140 31 4 FALSE 0.73
colorectal cancer KRAS_G12D NSD1 158 51 Male -0.94 -2.07 -0.03 114.04 1.03 1035 156 49 2 FALSE 1.01
non-small cell lung cancer KRAS_G12D NSD1 104 50 Female -5.32 -11.41 -1.31 979.29 1.00 1994 104 50 0 FALSE 1.40
non-small cell lung cancer KRAS_G12D NSD1 48 40 Male -5.34 -11.55 -1.15 885.40 1.00 1462 48 40 0 FALSE 1.38
uterine cancer KRAS_G12D NSD1 56 123 Female 0.13 -0.72 0.93 1214.21 1.00 978 49 116 7 FALSE 0.12
colorectal cancer KRAS_G12D NSD1 302 86 Sex:overall -0.85 -2.05 0.18 127.84 1.03 1915 296 80 6 FALSE 0.80
non-small cell lung cancer KRAS_G12D NSD1 152 90 Sex:overall -5.25 -11.40 -1.10 879.54 1.00 3456 152 90 0 FALSE 1.39
uterine cancer KRAS_G12D NSD1 56 123 Sex:overall 0.06 -4.21 4.38 1509.59 1.00 978 49 116 7 FALSE 0.01
colorectal cancer KRAS_G12D FLT4 144 70 Female -0.16 -0.93 0.43 220.77 1.03 852 138 64 6 TRUE 0.19
colorectal cancer KRAS_G12D FLT4 160 69 Male 0.08 -0.58 0.66 1079.39 1.00 1024 148 57 12 TRUE 0.10
non-small cell lung cancer KRAS_G12D FLT4 104 47 Female -1.07 -2.96 0.37 1233.21 1.00 2000 103 46 1 TRUE 0.68
non-small cell lung cancer KRAS_G12D FLT4 48 55 Male -1.00 -3.01 0.46 1251.40 1.00 1449 47 54 1 TRUE 0.57
uterine cancer KRAS_G12D FLT4 53 52 Female -0.48 -2.44 0.88 1150.93 1.00 1016 51 50 2 TRUE 0.24
colorectal cancer KRAS_G12D FLT4 304 139 Sex:overall -0.04 -0.87 0.62 773.71 1.01 1876 286 121 18 TRUE 0.04
non-small cell lung cancer KRAS_G12D FLT4 152 102 Sex:overall -1.01 -3.10 0.69 1476.57 1.00 3449 150 100 2 TRUE 0.54
uterine cancer KRAS_G12D FLT4 53 52 Sex:overall -0.41 -4.48 4.05 1493.48 1.00 1016 51 50 2 TRUE 0.07
cancer of unknown primary KRAS_G12D PTPRD 35 29 Female -1.86 -4.70 0.24 926.36 1.00 368 34 28 1 FALSE 0.87
cancer of unknown primary KRAS_G12D PTPRD 19 28 Male -2.12 -5.30 0.19 1010.23 1.00 343 19 28 0 FALSE 0.88
colorectal cancer KRAS_G12D PTPRD 144 48 Female -0.41 -1.16 0.26 1235.50 1.00 869 139 43 5 FALSE 0.57
colorectal cancer KRAS_G12D PTPRD 158 55 Male -0.42 -1.17 0.28 1185.11 1.00 1040 153 50 5 FALSE 0.58
non-small cell lung cancer KRAS_G12D PTPRD 104 235 Female -0.13 -0.81 0.43 1411.02 1.00 1861 95 226 9 FALSE 0.16
non-small cell lung cancer KRAS_G12D PTPRD 48 156 Male 0.14 -0.60 0.86 1389.48 1.00 1369 41 149 7 FALSE 0.15
uterine cancer KRAS_G12D PTPRD 53 99 Female -2.04 -4.61 -0.34 1422.20 1.00 999 52 98 1 FALSE 1.20
cancer of unknown primary KRAS_G12D PTPRD 54 57 Sex:overall -1.99 -4.96 0.28 951.29 1.00 711 53 56 1 FALSE 0.89
colorectal cancer KRAS_G12D PTPRD 302 103 Sex:overall -0.41 -1.25 0.30 1192.92 1.00 1909 292 93 10 FALSE 0.52
non-small cell lung cancer KRAS_G12D PTPRD 152 391 Sex:overall 0.00 -0.94 0.99 1867.70 1.00 3230 136 375 16 FALSE 0.00
uterine cancer KRAS_G12D PTPRD 53 99 Sex:overall -1.81 -5.97 2.88 1398.13 1.00 999 52 98 1 FALSE 0.41
colorectal cancer KRAS_G12D RET 160 36 Female -1.20 -2.67 -0.15 1022.46 1.00 958 159 35 1 TRUE 1.07
colorectal cancer KRAS_G12D RET 183 29 Male -0.90 -2.20 0.20 1341.77 1.00 1156 180 26 3 TRUE 0.83
non-small cell lung cancer KRAS_G12D RET 107 55 Female -0.87 -2.75 0.44 936.93 1.00 2054 105 53 2 TRUE 0.56
non-small cell lung cancer KRAS_G12D RET 50 38 Male -1.23 -3.91 0.45 1105.74 1.00 1523 50 38 0 TRUE 0.55
colorectal cancer KRAS_G12D RET 343 65 Sex:overall -1.05 -2.64 0.16 1295.77 1.00 2114 339 61 4 TRUE 0.86
non-small cell lung cancer KRAS_G12D RET 157 93 Sex:overall -1.03 -3.29 0.58 935.62 1.00 3577 155 91 2 TRUE 0.54
colorectal cancer KRAS_G12D KDM5A 144 31 Female -0.43 -1.42 0.50 1045.67 1.00 881 140 27 4 FALSE 0.42
colorectal cancer KRAS_G12D KDM5A 160 65 Male -0.71 -1.71 0.05 1382.20 1.00 1028 156 61 4 FALSE 0.97
non-small cell lung cancer KRAS_G12D KDM5A 104 37 Female -1.60 -4.14 0.36 297.82 1.01 2008 103 36 1 FALSE 0.73
non-small cell lung cancer KRAS_G12D KDM5A 48 36 Male -1.94 -5.35 0.24 605.76 1.01 1469 48 36 0 FALSE 0.72
uterine cancer KRAS_G12D KDM5A 53 65 Female -0.72 -2.55 0.59 1305.51 1.00 1009 51 63 2 FALSE 0.44
colorectal cancer KRAS_G12D KDM5A 304 96 Sex:overall -0.58 -1.90 0.51 1436.48 1.00 1909 296 88 8 FALSE 0.49
non-small cell lung cancer KRAS_G12D KDM5A 152 73 Sex:overall -1.74 -4.59 0.38 473.25 1.01 3477 151 72 1 FALSE 0.72
uterine cancer KRAS_G12D KDM5A 53 65 Sex:overall -0.51 -4.89 3.98 1318.10 1.00 1009 51 63 2 FALSE 0.09
colorectal cancer KRAS_G12D PIK3C2G 139 30 Female -2.08 -4.13 -0.66 1342.21 1.00 853 138 29 1 FALSE 1.77
colorectal cancer KRAS_G12D PIK3C2G 152 57 Male -2.17 -4.11 -0.76 1200.15 1.00 1004 151 56 1 FALSE 2.05
non-small cell lung cancer KRAS_G12D PIK3C2G 104 70 Female -0.21 -1.36 0.72 1184.12 1.00 1967 101 67 3 FALSE 0.17
non-small cell lung cancer KRAS_G12D PIK3C2G 47 61 Male -0.16 -1.41 0.89 1126.77 1.00 1444 45 59 2 FALSE 0.11
colorectal cancer KRAS_G12D PIK3C2G 291 87 Sex:overall -2.11 -4.09 -0.58 1204.54 1.00 1857 289 85 2 FALSE 1.82
non-small cell lung cancer KRAS_G12D PIK3C2G 151 131 Sex:overall -0.20 -1.51 0.96 1103.67 1.00 3411 146 126 5 FALSE 0.12
non-small cell lung cancer KRAS_G12D TSHR 105 47 Female -0.11 -1.49 1.01 1430.05 1.00 2001 102 44 3 TRUE 0.06
non-small cell lung cancer KRAS_G12D TSHR 48 22 Male -0.74 -3.80 0.97 1270.83 1.00 1480 48 22 0 TRUE 0.25
non-small cell lung cancer KRAS_G12D TSHR 153 69 Sex:overall -0.37 -2.60 1.36 1483.46 1.00 3481 150 66 3 TRUE 0.15
cancer of unknown primary KRAS_G12D CREBBP 35 25 Female -0.95 -2.93 0.48 946.58 1.00 367 34 24 1 TRUE 0.55
cancer of unknown primary KRAS_G12D CREBBP 19 31 Male -0.87 -2.97 0.63 1189.60 1.00 343 18 30 1 TRUE 0.46
colorectal cancer KRAS_G12D CREBBP 146 81 Female -0.64 -1.75 0.06 723.49 1.00 846 142 77 4 TRUE 0.80
colorectal cancer KRAS_G12D CREBBP 163 107 Male -0.17 -0.74 0.45 1361.60 1.00 1005 148 92 15 TRUE 0.23
non-small cell lung cancer KRAS_G12D CREBBP 104 82 Female -0.47 -1.71 0.58 1266.13 1.00 1970 101 79 3 TRUE 0.38
non-small cell lung cancer KRAS_G12D CREBBP 48 60 Male -0.58 -2.05 0.58 1303.04 1.00 1447 47 59 1 TRUE 0.42
uterine cancer KRAS_G12D CREBBP 53 95 Female -1.13 -2.94 0.20 1291.88 1.00 989 51 93 2 TRUE 0.82
cancer of unknown primary KRAS_G12D CREBBP 54 56 Sex:overall -0.92 -3.02 0.58 955.72 1.00 710 52 54 2 TRUE 0.48
colorectal cancer KRAS_G12D CREBBP 309 188 Sex:overall -0.41 -1.44 0.38 1386.27 1.00 1851 290 169 19 TRUE 0.40
non-small cell lung cancer KRAS_G12D CREBBP 152 142 Sex:overall -0.52 -1.94 0.77 1319.28 1.00 3417 148 138 4 TRUE 0.34
uterine cancer KRAS_G12D CREBBP 53 95 Sex:overall -0.98 -5.37 3.98 1515.40 1.00 989 51 93 2 TRUE 0.19
non-small cell lung cancer KRAS_G12D BRIP1 104 36 Female -1.47 -4.09 0.38 1267.10 1.00 2009 103 35 1 TRUE 0.68
non-small cell lung cancer KRAS_G12D BRIP1 48 34 Male -1.75 -4.82 0.35 1328.86 1.00 1468 48 34 0 TRUE 0.68
non-small cell lung cancer KRAS_G12D BRIP1 152 70 Sex:overall -1.57 -4.40 0.55 1338.70 1.00 3477 151 69 1 TRUE 0.66
colorectal cancer KRAS_G12D AXIN2 144 48 Female -0.67 -1.90 0.06 1235.61 1.00 869 142 46 2 TRUE 0.85
colorectal cancer KRAS_G12D AXIN2 158 67 Male -0.33 -0.98 0.44 149.94 1.02 1026 149 58 9 TRUE 0.43
non-small cell lung cancer KRAS_G12D AXIN2 104 31 Female -0.19 -1.84 1.08 1456.22 1.00 2013 103 30 1 TRUE 0.10
non-small cell lung cancer KRAS_G12D AXIN2 48 31 Male 0.17 -1.45 1.49 1408.16 1.00 1473 46 29 2 TRUE 0.09
uterine cancer KRAS_G12D AXIN2 53 52 Female 0.07 -1.31 1.11 1548.87 1.00 1013 50 49 3 TRUE 0.04
colorectal cancer KRAS_G12D AXIN2 302 115 Sex:overall -0.51 -1.59 0.42 1275.54 1.00 1895 291 104 11 TRUE 0.51
non-small cell lung cancer KRAS_G12D AXIN2 152 62 Sex:overall -0.02 -1.67 1.50 1458.89 1.00 3486 149 59 3 TRUE 0.01
uterine cancer KRAS_G12D AXIN2 53 52 Sex:overall 0.13 -4.02 4.56 1513.02 1.00 1013 50 49 3 TRUE 0.02
colorectal cancer KRAS_G12D DOT1L 144 30 Female -0.54 -1.67 0.31 1127.82 1.00 880 142 28 2 FALSE 0.55
colorectal cancer KRAS_G12D DOT1L 159 54 Male -0.35 -1.22 0.38 1406.38 1.00 1037 153 48 6 FALSE 0.42
non-small cell lung cancer KRAS_G12D DOT1L 104 46 Female 0.23 -0.88 1.22 1590.39 1.00 2001 101 43 3 FALSE 0.18
non-small cell lung cancer KRAS_G12D DOT1L 48 61 Male 0.33 -0.80 1.32 1408.95 1.00 1446 45 58 3 FALSE 0.27
colorectal cancer KRAS_G12D DOT1L 303 84 Sex:overall -0.44 -1.48 0.47 1416.42 1.00 1917 295 76 8 FALSE 0.40
non-small cell lung cancer KRAS_G12D DOT1L 152 107 Sex:overall 0.30 -1.04 1.71 1389.87 1.00 3447 146 101 6 FALSE 0.17
colorectal cancer KRAS_G12D PTPRS 142 107 Female -0.20 -0.74 0.27 1068.76 1.00 798 131 96 11 FALSE 0.36
colorectal cancer KRAS_G12D PTPRS 156 147 Male -0.06 -0.48 0.39 438.90 1.00 949 136 127 20 FALSE 0.10
non-small cell lung cancer KRAS_G12D PTPRS 104 43 Female -1.63 -4.50 0.16 1173.92 1.00 1991 103 42 1 FALSE 0.78
non-small cell lung cancer KRAS_G12D PTPRS 47 37 Male -1.89 -5.41 0.19 1300.43 1.00 1465 47 37 0 FALSE 0.73
colorectal cancer KRAS_G12D PTPRS 298 254 Sex:overall -0.13 -0.73 0.52 1414.88 1.00 1747 267 223 31 FALSE 0.15
non-small cell lung cancer KRAS_G12D PTPRS 151 80 Sex:overall -1.74 -4.71 0.33 1263.98 1.00 3456 150 79 1 FALSE 0.74
cancer of unknown primary KRAS_G12D SMARCA4 35 31 Female -0.81 -2.27 0.49 142.35 1.02 360 34 30 1 FALSE 0.55
cancer of unknown primary KRAS_G12D SMARCA4 19 35 Male -0.53 -1.89 0.88 88.29 1.02 335 17 33 2 FALSE 0.31
colorectal cancer KRAS_G12D SMARCA4 145 77 Female -0.12 -0.70 0.40 687.55 1.00 851 136 68 9 FALSE 0.18
colorectal cancer KRAS_G12D SMARCA4 160 92 Male -0.08 -0.59 0.44 826.65 1.00 1017 148 80 12 FALSE 0.12
non-small cell lung cancer KRAS_G12D SMARCA4 105 163 Female 0.32 -0.31 0.93 1132.11 1.00 1906 93 151 12 FALSE 0.48
non-small cell lung cancer KRAS_G12D SMARCA4 48 150 Male -0.18 -1.28 0.63 1392.25 1.00 1362 45 147 3 FALSE 0.15
uterine cancer KRAS_G12D SMARCA4 55 102 Female -0.06 -1.12 0.83 1283.65 1.00 987 50 97 5 FALSE 0.04
cancer of unknown primary KRAS_G12D SMARCA4 54 66 Sex:overall -0.68 -2.14 0.78 112.45 1.02 695 51 63 3 FALSE 0.40
colorectal cancer KRAS_G12D SMARCA4 305 169 Sex:overall -0.10 -0.73 0.50 945.08 1.00 1868 284 148 21 FALSE 0.13
non-small cell lung cancer KRAS_G12D SMARCA4 153 313 Sex:overall 0.06 -1.18 1.11 1495.53 1.00 3268 138 298 15 FALSE 0.03
uterine cancer KRAS_G12D SMARCA4 55 102 Sex:overall 0.04 -3.94 4.12 1724.97 1.00 987 50 97 5 FALSE 0.01
cancer of unknown primary KRAS_G12D PTPRT 35 30 Female -0.87 -2.82 0.56 755.26 1.00 368 33 28 2 FALSE 0.51
cancer of unknown primary KRAS_G12D PTPRT 19 28 Male -1.36 -4.10 0.46 1044.81 1.00 343 19 28 0 FALSE 0.57
colorectal cancer KRAS_G12D PTPRT 144 71 Female -0.57 -1.24 0.03 1351.00 1.00 846 138 65 6 FALSE 1.06
colorectal cancer KRAS_G12D PTPRT 159 114 Male -0.52 -1.14 0.02 1092.29 1.00 986 149 104 10 FALSE 1.13
non-small cell lung cancer KRAS_G12D PTPRT 106 205 Female -0.28 -0.98 0.36 1266.52 1.00 1881 98 197 8 FALSE 0.38
non-small cell lung cancer KRAS_G12D PTPRT 49 146 Male -0.26 -1.08 0.49 1217.37 1.00 1384 45 142 4 FALSE 0.29
uterine cancer KRAS_G12D PTPRT 53 87 Female -1.02 -2.84 0.31 909.61 1.00 992 51 85 2 FALSE 0.69
cancer of unknown primary KRAS_G12D PTPRT 54 58 Sex:overall -1.08 -3.25 0.68 893.56 1.00 711 52 56 2 FALSE 0.53
colorectal cancer KRAS_G12D PTPRT 303 185 Sex:overall -0.54 -1.29 0.25 1352.98 1.00 1832 287 169 16 FALSE 0.73
non-small cell lung cancer KRAS_G12D PTPRT 155 351 Sex:overall -0.28 -1.31 0.67 1524.64 1.00 3265 143 339 12 FALSE 0.24
uterine cancer KRAS_G12D PTPRT 53 87 Sex:overall -0.89 -5.12 4.22 1528.08 1.00 992 51 85 2 FALSE 0.18
colorectal cancer KRAS_G12D HGF 144 14 Female -0.18 -1.42 0.98 1394.93 1.00 895 142 12 2 FALSE 0.11
colorectal cancer KRAS_G12D HGF 158 42 Male -0.13 -1.08 0.73 1562.76 1.00 1042 153 37 5 FALSE 0.11
non-small cell lung cancer KRAS_G12D HGF 104 108 Female -0.16 -1.08 0.61 1103.79 1.00 1947 99 103 5 FALSE 0.14
non-small cell lung cancer KRAS_G12D HGF 48 83 Male -0.25 -1.42 0.67 950.02 1.00 1427 46 81 2 FALSE 0.19
colorectal cancer KRAS_G12D HGF 302 56 Sex:overall -0.15 -1.72 1.32 1213.16 1.00 1937 295 49 7 FALSE 0.07
non-small cell lung cancer KRAS_G12D HGF 152 191 Sex:overall -0.19 -1.35 0.88 1529.76 1.00 3374 145 184 7 FALSE 0.13
colorectal cancer KRAS_G12D BLM 144 26 Female -1.33 -2.87 -0.11 668.63 1.00 884 142 24 2 TRUE 1.25
colorectal cancer KRAS_G12D BLM 158 44 Male -1.51 -3.08 -0.42 585.82 1.00 1039 157 43 1 TRUE 1.55
colorectal cancer KRAS_G12D BLM 302 70 Sex:overall -1.40 -3.06 -0.19 753.75 1.00 1923 299 67 3 TRUE 1.23
cancer of unknown primary KRAS_G12D PIK3CA 35 64 Female -0.43 -1.62 0.59 1352.65 1.00 342 31 60 4 TRUE 0.37
cancer of unknown primary KRAS_G12D PIK3CA 19 30 Male -0.55 -2.25 0.76 1416.58 1.00 345 18 29 1 TRUE 0.32
colorectal cancer KRAS_G12D PIK3CA 161 244 Female 0.28 -0.09 0.57 567.82 1.00 808 124 207 37 TRUE 0.98
colorectal cancer KRAS_G12D PIK3CA 189 267 Male 0.36 0.05 0.68 774.74 1.00 989 140 218 49 TRUE 1.66
non-small cell lung cancer KRAS_G12D PIK3CA 107 141 Female 0.26 -0.43 0.91 1382.75 1.00 1983 97 131 10 TRUE 0.35
non-small cell lung cancer KRAS_G12D PIK3CA 50 101 Male -0.07 -1.17 0.73 1120.65 1.00 1461 48 99 2 TRUE 0.06
uterine cancer KRAS_G12D PIK3CA 63 557 Female 0.87 0.40 1.37 1282.47 1.00 773 24 518 39 TRUE 3.21
cancer of unknown primary KRAS_G12D PIK3CA 54 94 Sex:overall -0.47 -2.21 1.07 1385.39 1.00 687 49 89 5 TRUE 0.24
colorectal cancer KRAS_G12D PIK3CA 350 511 Sex:overall 0.32 -0.15 0.77 1356.33 1.00 1797 264 425 86 TRUE 0.63
non-small cell lung cancer KRAS_G12D PIK3CA 157 242 Sex:overall 0.11 -1.01 1.03 1463.47 1.00 3444 145 230 12 TRUE 0.07
uterine cancer KRAS_G12D PIK3CA 63 557 Sex:overall 0.73 -3.63 4.70 1649.05 1.00 773 24 518 39 TRUE 0.14
non-small cell lung cancer KRAS_G12D GATA3 104 40 Female -1.85 -5.41 0.19 1013.47 1.00 2006 104 40 0 FALSE 0.63
non-small cell lung cancer KRAS_G12D GATA3 48 26 Male -1.27 -3.97 0.79 831.93 1.00 1478 47 25 1 FALSE 0.51
non-small cell lung cancer KRAS_G12D GATA3 152 66 Sex:overall -1.50 -4.37 0.60 806.03 1.00 3484 151 65 1 FALSE 0.58
colorectal cancer KRAS_G12D ESR1 144 26 Female -0.57 -2.16 0.54 452.71 1.00 883 143 25 1 TRUE 0.39
colorectal cancer KRAS_G12D ESR1 158 46 Male -0.07 -1.08 0.70 470.92 1.00 1038 151 39 7 TRUE 0.06
non-small cell lung cancer KRAS_G12D ESR1 104 30 Female -0.24 -1.99 1.14 1349.74 1.00 2018 102 28 2 TRUE 0.11
non-small cell lung cancer KRAS_G12D ESR1 48 26 Male -0.77 -3.82 0.91 1251.37 1.00 1476 48 26 0 TRUE 0.24
colorectal cancer KRAS_G12D ESR1 302 72 Sex:overall -0.33 -1.70 0.67 551.85 1.00 1921 294 64 8 TRUE 0.22
non-small cell lung cancer KRAS_G12D ESR1 152 56 Sex:overall -0.50 -2.87 1.27 1271.26 1.00 3494 150 54 2 TRUE 0.19
colorectal cancer KRAS_G12D ALK 160 55 Female -0.84 -1.91 -0.05 1116.19 1.00 944 158 53 2 TRUE 1.09
colorectal cancer KRAS_G12D ALK 183 60 Male -0.58 -1.35 0.17 1103.74 1.00 1138 176 53 7 TRUE 0.89
non-small cell lung cancer KRAS_G12D ALK 107 90 Female -0.17 -1.32 0.72 546.75 1.01 2026 102 85 5 TRUE 0.13
non-small cell lung cancer KRAS_G12D ALK 50 79 Male -1.18 -4.70 0.38 295.74 1.01 1485 50 79 0 TRUE 0.43
uterine cancer KRAS_G12D ALK 55 53 Female -1.33 -4.02 0.56 1383.98 1.00 1128 54 52 1 TRUE 0.59
colorectal cancer KRAS_G12D ALK 343 115 Sex:overall -0.71 -1.69 0.08 1390.56 1.00 2082 334 106 9 TRUE 0.91
non-small cell lung cancer KRAS_G12D ALK 157 169 Sex:overall -0.64 -2.97 0.85 953.04 1.00 3511 152 164 5 TRUE 0.27
uterine cancer KRAS_G12D ALK 55 53 Sex:overall -1.13 -5.81 3.47 1452.37 1.00 1128 54 52 1 TRUE 0.21
colorectal cancer KRAS_G12D RNF43 144 140 Female -1.61 -2.69 -0.69 1136.87 1.00 807 140 136 4 TRUE 2.81
colorectal cancer KRAS_G12D RNF43 166 127 Male 0.47 -0.03 0.92 1224.97 1.00 997 141 102 25 TRUE 1.28
pancreatic cancer KRAS_G12D RNF43 238 34 Female 0.49 0.01 1.00 1149.92 1.00 470 223 19 15 TRUE 1.29
pancreatic cancer KRAS_G12D RNF43 265 46 Male 0.51 0.04 1.00 1142.52 1.00 524 245 26 20 TRUE 1.41
uterine cancer KRAS_G12D RNF43 56 95 Female 0.41 -0.48 1.17 1242.26 1.00 982 49 88 7 TRUE 0.48
colorectal cancer KRAS_G12D RNF43 310 267 Sex:overall -0.56 -2.75 1.39 1614.50 1.00 1804 281 238 29 TRUE 0.23
pancreatic cancer KRAS_G12D RNF43 503 80 Sex:overall 0.51 -0.07 1.10 1192.31 1.00 994 468 45 35 TRUE 1.01
uterine cancer KRAS_G12D RNF43 56 95 Sex:overall 0.35 -3.74 4.58 1685.68 1.00 982 49 88 7 TRUE 0.07
non-small cell lung cancer KRAS_G12D U2AF1 104 52 Female 0.38 -0.69 1.31 1480.56 1.00 1994 101 49 3 FALSE 0.34
non-small cell lung cancer KRAS_G12D U2AF1 49 26 Male 0.83 -0.32 1.99 1339.92 1.00 1480 46 23 3 FALSE 0.79
non-small cell lung cancer KRAS_G12D U2AF1 153 78 Sex:overall 0.60 -0.81 1.97 1493.69 1.00 3474 147 72 6 FALSE 0.41
colorectal cancer KRAS_G12D LATS1 139 19 Female -0.85 -2.27 0.28 1147.01 1.00 860 138 18 1 FALSE 0.71
colorectal cancer KRAS_G12D LATS1 152 36 Male -0.72 -2.02 0.29 1116.03 1.00 1023 149 33 3 FALSE 0.68
non-small cell lung cancer KRAS_G12D LATS1 104 41 Female -1.40 -5.30 0.52 1428.19 1.00 1991 104 41 0 FALSE 0.43
non-small cell lung cancer KRAS_G12D LATS1 47 27 Male -0.09 -2.22 1.62 1277.47 1.00 1473 45 25 2 FALSE 0.03
colorectal cancer KRAS_G12D LATS1 291 55 Sex:overall -0.77 -2.14 0.47 1220.18 1.00 1883 287 51 4 FALSE 0.59
non-small cell lung cancer KRAS_G12D LATS1 151 68 Sex:overall -0.71 -3.42 1.19 1502.56 1.00 3464 149 66 2 FALSE 0.26
colorectal cancer KRAS_G12D LATS2 139 26 Female -0.49 -2.31 0.62 244.73 1.02 855 138 25 1 FALSE 0.28
colorectal cancer KRAS_G12D LATS2 152 44 Male 0.30 -0.49 1.04 1419.77 1.00 1016 143 35 9 FALSE 0.36
non-small cell lung cancer KRAS_G12D LATS2 104 30 Female -1.43 -4.57 0.58 190.53 1.01 2004 103 29 1 FALSE 0.55
non-small cell lung cancer KRAS_G12D LATS2 47 31 Male -1.78 -5.16 0.48 337.44 1.00 1468 47 31 0 FALSE 0.60
colorectal cancer KRAS_G12D LATS2 291 70 Sex:overall -0.10 -1.72 1.01 727.40 1.01 1871 281 60 10 FALSE 0.05
non-small cell lung cancer KRAS_G12D LATS2 151 61 Sex:overall -1.57 -4.69 0.76 262.33 1.01 3472 150 60 1 FALSE 0.56
colorectal cancer KRAS_G12D PTEN 160 80 Female -0.57 -1.30 0.04 1192.39 1.00 937 155 75 5 TRUE 1.06
colorectal cancer KRAS_G12D PTEN 185 105 Male -0.42 -0.98 0.15 1518.54 1.00 1111 173 93 12 TRUE 0.83
non-small cell lung cancer KRAS_G12D PTEN 107 60 Female -0.71 -2.17 0.55 1386.91 1.00 2049 105 58 2 TRUE 0.51
non-small cell lung cancer KRAS_G12D PTEN 50 76 Male -0.88 -2.67 0.44 1394.78 1.00 1489 49 75 1 TRUE 0.60
uterine cancer KRAS_G12D PTEN 78 627 Female 0.91 0.46 1.39 1390.44 1.00 801 28 577 50 TRUE 3.83
colorectal cancer KRAS_G12D PTEN 345 185 Sex:overall -0.49 -1.20 0.16 1019.96 1.00 2048 328 168 17 TRUE 0.58
non-small cell lung cancer KRAS_G12D PTEN 157 136 Sex:overall -0.77 -2.52 0.77 1457.83 1.00 3538 154 133 3 TRUE 0.45
uterine cancer KRAS_G12D PTEN 78 627 Sex:overall 0.81 -3.70 5.22 1509.01 1.00 801 28 577 50 TRUE 0.16
colorectal cancer KRAS_G12D BCOR 144 59 Female -0.15 -0.85 0.50 1323.20 1.00 868 136 51 8 FALSE 0.18
colorectal cancer KRAS_G12D BCOR 158 53 Male -0.24 -0.96 0.38 1184.49 1.00 1032 153 48 5 FALSE 0.32
non-small cell lung cancer KRAS_G12D BCOR 104 103 Female 0.04 -0.93 0.86 1325.66 1.00 1955 98 97 6 FALSE 0.03
non-small cell lung cancer KRAS_G12D BCOR 48 31 Male -1.06 -4.94 0.82 1420.34 1.00 1473 48 31 0 FALSE 0.31
uterine cancer KRAS_G12D BCOR 53 140 Female 0.73 0.01 1.39 1400.15 1.00 953 41 128 12 FALSE 1.49
colorectal cancer KRAS_G12D BCOR 302 112 Sex:overall -0.19 -0.96 0.55 1381.45 1.00 1900 289 99 13 FALSE 0.18
non-small cell lung cancer KRAS_G12D BCOR 152 134 Sex:overall -0.46 -3.01 1.38 989.99 1.00 3428 146 128 6 FALSE 0.17
uterine cancer KRAS_G12D BCOR 53 140 Sex:overall 0.56 -3.92 4.68 1256.12 1.00 953 41 128 12 FALSE 0.11
colorectal cancer KRAS_G12D CTNNB1 160 74 Female 0.41 -0.05 0.84 1014.99 1.00 934 146 60 14 TRUE 1.14
colorectal cancer KRAS_G12D CTNNB1 186 89 Male 0.41 -0.02 0.83 798.42 1.00 1111 169 72 17 TRUE 1.20
non-small cell lung cancer KRAS_G12D CTNNB1 108 74 Female -0.42 -1.59 0.62 800.27 1.01 2036 105 71 3 TRUE 0.32
non-small cell lung cancer KRAS_G12D CTNNB1 50 47 Male -0.50 -1.94 0.73 1605.14 1.00 1513 49 46 1 TRUE 0.33
uterine cancer KRAS_G12D CTNNB1 55 143 Female -1.03 -2.50 0.10 1180.34 1.00 1032 52 140 3 TRUE 0.94
colorectal cancer KRAS_G12D CTNNB1 346 163 Sex:overall 0.41 -0.08 0.90 1072.89 1.00 2045 315 132 31 TRUE 0.91
non-small cell lung cancer KRAS_G12D CTNNB1 158 121 Sex:overall -0.45 -1.96 0.78 1428.46 1.00 3549 154 117 4 TRUE 0.28
uterine cancer KRAS_G12D CTNNB1 55 143 Sex:overall -0.81 -4.95 3.99 1554.18 1.00 1032 52 140 3 TRUE 0.15
cancer of unknown primary KRAS_G12D ARID1A 36 65 Female -0.42 -1.54 0.55 205.63 1.02 343 33 62 3 TRUE 0.37
cancer of unknown primary KRAS_G12D ARID1A 19 51 Male 0.00 -1.04 1.18 73.93 1.04 329 15 47 4 TRUE 0.00
colorectal cancer KRAS_G12D ARID1A 147 149 Female -0.43 -1.07 0.04 549.26 1.00 817 136 138 11 TRUE 0.86
colorectal cancer KRAS_G12D ARID1A 165 166 Male -0.15 -0.69 0.33 485.88 1.00 969 142 143 23 TRUE 0.25
non-small cell lung cancer KRAS_G12D ARID1A 104 132 Female -0.60 -1.57 0.29 1484.67 1.00 1925 100 128 4 TRUE 0.68
non-small cell lung cancer KRAS_G12D ARID1A 48 152 Male -0.60 -1.66 0.30 1358.47 1.00 1368 45 149 3 TRUE 0.61
pancreatic cancer KRAS_G12D ARID1A 239 62 Female 0.46 0.04 0.85 1257.45 1.00 454 214 37 25 TRUE 1.63
pancreatic cancer KRAS_G12D ARID1A 265 65 Male 0.51 0.11 0.92 1136.98 1.00 516 235 35 30 TRUE 1.88
uterine cancer KRAS_G12D ARID1A 62 527 Female 0.54 0.08 1.09 50.55 1.04 734 28 493 34 TRUE 1.19
cancer of unknown primary KRAS_G12D ARID1A 55 116 Sex:overall -0.22 -1.58 1.11 180.89 1.02 672 48 109 7 TRUE 0.12
colorectal cancer KRAS_G12D ARID1A 312 315 Sex:overall -0.29 -1.03 0.32 1251.40 1.00 1786 278 281 34 TRUE 0.36
non-small cell lung cancer KRAS_G12D ARID1A 152 284 Sex:overall -0.58 -1.75 0.59 1436.79 1.00 3293 145 277 7 TRUE 0.47
pancreatic cancer KRAS_G12D ARID1A 504 127 Sex:overall 0.48 0.00 0.94 1369.69 1.00 970 449 72 55 TRUE 1.19
uterine cancer KRAS_G12D ARID1A 62 527 Sex:overall 0.43 -3.79 4.59 1344.09 1.00 734 28 493 34 TRUE 0.09
colorectal cancer KRAS_G12D PIK3R1 144 44 Female -0.34 -1.38 0.42 1261.68 1.00 869 141 41 3 TRUE 0.34
colorectal cancer KRAS_G12D PIK3R1 161 72 Male 0.07 -0.60 0.71 1282.90 1.00 1027 149 60 12 TRUE 0.08
non-small cell lung cancer KRAS_G12D PIK3R1 104 30 Female 0.10 -1.43 1.23 1373.88 1.00 2016 102 28 2 TRUE 0.06
non-small cell lung cancer KRAS_G12D PIK3R1 48 25 Male 0.08 -1.61 1.37 1519.24 1.00 1479 47 24 1 TRUE 0.04
uterine cancer KRAS_G12D PIK3R1 55 268 Female -0.50 -1.26 0.24 432.80 1.01 849 46 259 9 TRUE 0.73
colorectal cancer KRAS_G12D PIK3R1 305 116 Sex:overall -0.14 -1.22 0.71 1348.24 1.00 1896 290 101 15 TRUE 0.10
non-small cell lung cancer KRAS_G12D PIK3R1 152 55 Sex:overall 0.10 -1.63 1.46 1481.46 1.00 3495 149 52 3 TRUE 0.05
uterine cancer KRAS_G12D PIK3R1 55 268 Sex:overall -0.36 -4.72 4.21 1604.91 1.00 849 46 259 9 TRUE 0.07
colorectal cancer KRAS_G12D IKZF1 144 42 Female -0.11 -0.93 0.56 841.51 1.00 873 139 37 5 TRUE 0.11
colorectal cancer KRAS_G12D IKZF1 159 44 Male -0.09 -0.86 0.54 934.26 1.00 1038 153 38 6 TRUE 0.09
non-small cell lung cancer KRAS_G12D IKZF1 104 48 Female -0.52 -2.19 0.75 1223.04 1.00 1997 103 47 1 TRUE 0.30
non-small cell lung cancer KRAS_G12D IKZF1 48 34 Male -0.10 -1.63 1.24 935.20 1.00 1471 46 32 2 TRUE 0.05
colorectal cancer KRAS_G12D IKZF1 303 86 Sex:overall -0.10 -0.94 0.58 888.22 1.00 1911 292 75 11 TRUE 0.10
non-small cell lung cancer KRAS_G12D IKZF1 152 82 Sex:overall -0.31 -2.08 1.20 1426.83 1.00 3468 149 79 3 TRUE 0.15
cancer of unknown primary KRAS_G12D TERT 35 27 Female -1.94 -5.00 0.16 1314.43 1.00 364 34 26 1 TRUE 0.91
cancer of unknown primary KRAS_G12D TERT 19 58 Male -2.74 -6.50 -0.40 1437.60 1.00 320 19 58 0 TRUE 1.06
colorectal cancer KRAS_G12D TERT 147 40 Female 0.47 -0.15 1.14 931.86 1.00 876 137 30 10 TRUE 0.81
colorectal cancer KRAS_G12D TERT 159 58 Male 0.29 -0.38 0.85 1367.41 1.00 1033 151 50 8 TRUE 0.45
non-small cell lung cancer KRAS_G12D TERT 104 87 Female -0.36 -1.51 0.62 1297.12 1.00 1964 100 83 4 TRUE 0.30
non-small cell lung cancer KRAS_G12D TERT 48 79 Male -0.64 -2.21 0.47 1323.82 1.00 1429 47 78 1 TRUE 0.47
uterine cancer KRAS_G12D TERT 53 65 Female -1.69 -4.41 0.15 1129.52 1.00 994 52 64 1 TRUE 0.82
cancer of unknown primary KRAS_G12D TERT 54 85 Sex:overall -2.25 -5.33 0.19 1259.64 1.00 684 53 84 1 TRUE 0.95
colorectal cancer KRAS_G12D TERT 306 98 Sex:overall 0.37 -0.48 1.10 1405.07 1.00 1909 288 80 18 TRUE 0.46
non-small cell lung cancer KRAS_G12D TERT 152 166 Sex:overall -0.52 -1.99 0.67 1199.85 1.00 3393 147 161 5 TRUE 0.34
uterine cancer KRAS_G12D TERT 53 65 Sex:overall -1.37 -5.84 3.58 1487.61 1.00 994 52 64 1 TRUE 0.26
cancer of unknown primary KRAS_G12D FAT1 36 34 Female -1.09 -2.92 0.41 161.36 1.01 362 34 32 2 FALSE 0.69
cancer of unknown primary KRAS_G12D FAT1 19 34 Male -1.51 -4.21 0.29 396.75 1.00 340 19 34 0 FALSE 0.72
colorectal cancer KRAS_G12D FAT1 145 97 Female -0.61 -1.22 -0.07 696.09 1.01 841 138 90 7 FALSE 1.40
colorectal cancer KRAS_G12D FAT1 162 130 Male -0.53 -1.08 0.02 680.21 1.00 1004 150 118 12 FALSE 1.26
non-small cell lung cancer KRAS_G12D FAT1 105 155 Female -0.01 -0.75 0.66 1462.08 1.00 1909 96 146 9 FALSE 0.01
non-small cell lung cancer KRAS_G12D FAT1 48 150 Male -0.55 -1.87 0.38 1571.93 1.00 1373 46 148 2 FALSE 0.48
uterine cancer KRAS_G12D FAT1 55 183 Female -0.49 -1.42 0.35 1075.67 1.00 958 49 177 6 FALSE 0.55
cancer of unknown primary KRAS_G12D FAT1 55 68 Sex:overall -1.28 -3.40 0.48 225.28 1.00 702 53 66 2 FALSE 0.68
colorectal cancer KRAS_G12D FAT1 307 227 Sex:overall -0.58 -1.26 0.01 787.85 1.01 1845 288 208 19 FALSE 1.02
non-small cell lung cancer KRAS_G12D FAT1 153 305 Sex:overall -0.27 -1.65 0.92 1407.11 1.00 3282 142 294 11 FALSE 0.17
uterine cancer KRAS_G12D FAT1 55 183 Sex:overall -0.42 -4.74 3.87 1490.90 1.00 958 49 177 6 FALSE 0.08
colorectal cancer KRAS_G12D FGFR4 146 19 Female 0.39 -0.48 1.26 1146.70 1.00 893 141 14 5 TRUE 0.44
colorectal cancer KRAS_G12D FGFR4 158 34 Male 0.16 -0.77 0.96 1075.28 1.00 1048 154 30 4 TRUE 0.15
colorectal cancer KRAS_G12D FGFR4 304 53 Sex:overall 0.28 -0.81 1.32 1364.35 1.00 1941 295 44 9 TRUE 0.21
colorectal cancer KRAS_G12D CIC 145 58 Female -0.23 -0.84 0.34 351.75 1.02 866 139 52 6 TRUE 0.36
colorectal cancer KRAS_G12D CIC 160 79 Male -0.16 -0.72 0.42 250.43 1.02 1021 150 69 10 TRUE 0.24
non-small cell lung cancer KRAS_G12D CIC 104 43 Female 0.52 -0.48 1.42 1387.07 1.00 2007 100 39 4 TRUE 0.54
non-small cell lung cancer KRAS_G12D CIC 48 49 Male 0.35 -0.97 1.39 1255.33 1.00 1464 46 47 2 TRUE 0.25
uterine cancer KRAS_G12D CIC 53 75 Female 0.23 -1.10 0.94 5.75 1.17 1003 49 71 4 TRUE 0.18
colorectal cancer KRAS_G12D CIC 305 137 Sex:overall -0.20 -0.82 0.43 358.53 1.01 1887 289 121 16 TRUE 0.26
non-small cell lung cancer KRAS_G12D CIC 152 92 Sex:overall 0.45 -0.92 1.69 1507.05 1.00 3471 146 86 6 TRUE 0.29
uterine cancer KRAS_G12D CIC 53 75 Sex:overall 0.28 -3.50 4.11 1208.06 1.01 1003 49 71 4 TRUE 0.06
colorectal cancer KRAS_G12D KDM6A 144 31 Female 0.43 -0.49 1.12 220.78 1.00 883 139 26 5 FALSE 0.53
colorectal cancer KRAS_G12D KDM6A 159 31 Male 0.57 -0.45 1.24 165.88 1.01 1053 151 23 8 FALSE 0.84
non-small cell lung cancer KRAS_G12D KDM6A 104 28 Female 0.08 -1.44 1.26 1310.33 1.00 2019 102 26 2 FALSE 0.05
non-small cell lung cancer KRAS_G12D KDM6A 48 33 Male -0.05 -1.73 1.26 1472.09 1.00 1472 47 32 1 FALSE 0.02
pancreatic cancer KRAS_G12D KDM6A 238 21 Female 0.16 -0.54 0.82 1202.10 1.00 475 231 14 7 FALSE 0.19
pancreatic cancer KRAS_G12D KDM6A 262 38 Male 0.35 -0.25 0.97 1165.42 1.00 527 246 22 16 FALSE 0.59
uterine cancer KRAS_G12D KDM6A 53 54 Female -0.52 -2.37 0.82 1336.81 1.00 1011 51 52 2 FALSE 0.28
colorectal cancer KRAS_G12D KDM6A 303 62 Sex:overall 0.50 -0.49 1.27 253.81 1.00 1936 290 49 13 FALSE 0.59
non-small cell lung cancer KRAS_G12D KDM6A 152 61 Sex:overall -0.01 -1.84 1.47 1477.08 1.00 3491 149 58 3 FALSE 0.01
pancreatic cancer KRAS_G12D KDM6A 500 59 Sex:overall 0.25 -0.58 1.04 1452.09 1.00 1002 477 36 23 FALSE 0.26
uterine cancer KRAS_G12D KDM6A 53 54 Sex:overall -0.38 -5.17 4.84 1423.08 1.00 1011 51 52 2 FALSE 0.06
colorectal cancer KRAS_G12D NCOR1 144 54 Female -0.56 -1.34 0.13 1218.46 1.00 862 140 50 4 FALSE 0.89
colorectal cancer KRAS_G12D NCOR1 159 81 Male -0.45 -1.12 0.19 1450.45 1.00 1022 151 73 8 FALSE 0.77
non-small cell lung cancer KRAS_G12D NCOR1 105 53 Female -0.36 -1.85 0.84 1021.59 1.00 1999 102 50 3 FALSE 0.22
non-small cell lung cancer KRAS_G12D NCOR1 48 51 Male -1.17 -4.59 0.45 1288.99 1.00 1454 48 51 0 FALSE 0.42
uterine cancer KRAS_G12D NCOR1 54 90 Female -0.12 -1.34 0.76 71.95 1.04 1002 50 86 4 FALSE 0.08
colorectal cancer KRAS_G12D NCOR1 303 135 Sex:overall -0.50 -1.29 0.25 1187.33 1.00 1884 291 123 12 FALSE 0.68
non-small cell lung cancer KRAS_G12D NCOR1 153 104 Sex:overall -0.71 -2.90 0.98 1414.51 1.00 3453 150 101 3 FALSE 0.30
uterine cancer KRAS_G12D NCOR1 54 90 Sex:overall -0.01 -4.30 4.70 1448.19 1.00 1002 50 86 4 FALSE 0.00
colorectal cancer KRAS_G12D POLE 144 59 Female -0.45 -0.99 0.23 17.60 1.09 863 138 53 6 TRUE 0.71
colorectal cancer KRAS_G12D POLE 159 82 Male -0.45 -1.00 0.17 48.88 1.06 1019 151 74 8 TRUE 0.75
non-small cell lung cancer KRAS_G12D POLE 104 67 Female -0.78 -2.68 0.42 1354.64 1.00 1983 103 66 1 TRUE 0.50
non-small cell lung cancer KRAS_G12D POLE 48 69 Male -0.21 -1.59 1.00 1646.55 1.00 1439 45 66 3 TRUE 0.12
uterine cancer KRAS_G12D POLE 54 111 Female 0.47 -0.39 1.23 1319.57 1.00 994 46 103 8 TRUE 0.60
colorectal cancer KRAS_G12D POLE 303 141 Sex:overall -0.45 -1.01 0.24 42.97 1.06 1882 289 127 14 TRUE 0.61
non-small cell lung cancer KRAS_G12D POLE 152 136 Sex:overall -0.47 -2.24 0.98 1457.03 1.00 3422 148 132 4 TRUE 0.25
uterine cancer KRAS_G12D POLE 54 111 Sex:overall 0.42 -3.80 5.03 1470.41 1.00 994 46 103 8 TRUE 0.08
non-small cell lung cancer KRAS_G12D CUL3 104 34 Female -1.55 -4.27 0.36 559.53 1.01 2015 103 33 1 FALSE 0.69
non-small cell lung cancer KRAS_G12D CUL3 48 43 Male -2.05 -5.60 0.20 1230.52 1.00 1462 48 43 0 FALSE 0.71
non-small cell lung cancer KRAS_G12D CUL3 152 77 Sex:overall -1.76 -4.80 0.38 954.20 1.00 3477 151 76 1 FALSE 0.71
colorectal cancer KRAS_G12D ABL1 160 34 Female -0.69 -1.76 0.18 1283.12 1.00 962 158 32 2 TRUE 0.84
colorectal cancer KRAS_G12D ABL1 183 39 Male -0.60 -1.54 0.20 1140.27 1.00 1152 179 35 4 TRUE 0.78
colorectal cancer KRAS_G12D ABL1 343 73 Sex:overall -0.66 -1.71 0.18 1256.43 1.00 2114 337 67 6 TRUE 0.76
colorectal cancer KRAS_G12D FOXP1 144 24 Female -0.47 -1.56 0.49 1164.31 1.00 886 141 21 3 FALSE 0.46
colorectal cancer KRAS_G12D FOXP1 158 46 Male -0.63 -1.71 0.28 1320.41 1.00 1037 155 43 3 FALSE 0.71
colorectal cancer KRAS_G12D FOXP1 302 70 Sex:overall -0.55 -1.70 0.52 1143.21 1.00 1923 296 64 6 FALSE 0.44
colorectal cancer KRAS_G12D NOTCH2 139 30 Female -0.38 -1.41 0.44 955.76 1.00 855 137 28 2 TRUE 0.38
colorectal cancer KRAS_G12D NOTCH2 152 43 Male -0.21 -1.03 0.54 1171.33 1.00 1017 146 37 6 TRUE 0.22
non-small cell lung cancer KRAS_G12D NOTCH2 104 62 Female -0.06 -1.19 0.85 1466.09 1.00 1978 101 59 3 TRUE 0.04
non-small cell lung cancer KRAS_G12D NOTCH2 47 53 Male 0.00 -1.23 1.08 1456.75 1.00 1452 45 51 2 TRUE 0.00
colorectal cancer KRAS_G12D NOTCH2 291 73 Sex:overall -0.30 -1.32 0.60 1316.05 1.00 1872 283 65 8 TRUE 0.26
non-small cell lung cancer KRAS_G12D NOTCH2 151 115 Sex:overall -0.03 -1.40 1.12 1413.43 1.00 3430 146 110 5 TRUE 0.01
non-small cell lung cancer KRAS_G12D DDR2 104 49 Female -2.23 -5.60 -0.28 1132.73 1.00 1994 104 49 0 TRUE 0.99
non-small cell lung cancer KRAS_G12D DDR2 48 49 Male -1.70 -4.31 0.26 780.53 1.00 1454 47 48 1 TRUE 0.81
uterine cancer KRAS_G12D DDR2 53 57 Female 0.32 -0.84 1.32 1412.48 1.00 1018 49 53 4 TRUE 0.25
non-small cell lung cancer KRAS_G12D DDR2 152 98 Sex:overall -1.92 -4.73 0.15 1050.15 1.00 3448 151 97 1 TRUE 0.88
uterine cancer KRAS_G12D DDR2 53 57 Sex:overall 0.20 -4.49 4.77 1494.11 1.00 1018 49 53 4 TRUE 0.03
colorectal cancer KRAS_G12D TGFBR2 144 53 Female 0.00 -0.70 0.55 1402.88 1.00 862 138 47 6 TRUE 0.01
colorectal cancer KRAS_G12D TGFBR2 159 61 Male 0.10 -0.53 0.64 1450.89 1.00 1027 149 51 10 TRUE 0.12
non-small cell lung cancer KRAS_G12D TGFBR2 104 35 Female 0.20 -1.34 1.27 1025.27 1.00 2015 101 32 3 TRUE 0.12
non-small cell lung cancer KRAS_G12D TGFBR2 48 21 Male -0.38 -3.13 1.13 1329.37 1.00 1481 48 21 0 TRUE 0.13
colorectal cancer KRAS_G12D TGFBR2 303 114 Sex:overall 0.04 -0.69 0.65 1379.03 1.00 1889 287 98 16 TRUE 0.05
non-small cell lung cancer KRAS_G12D TGFBR2 152 56 Sex:overall -0.05 -2.09 1.46 1187.10 1.00 3496 149 53 3 TRUE 0.02
colorectal cancer KRAS_G12D SMO 160 32 Female -0.13 -0.95 0.56 368.81 1.01 965 156 28 4 TRUE 0.13
colorectal cancer KRAS_G12D SMO 184 39 Male -0.12 -0.94 0.56 363.31 1.01 1151 179 34 5 TRUE 0.13
non-small cell lung cancer KRAS_G12D SMO 107 39 Female 0.81 -0.23 1.61 120.31 1.04 2075 102 34 5 TRUE 1.03
non-small cell lung cancer KRAS_G12D SMO 50 36 Male 0.45 -1.14 1.42 38.42 1.08 1523 49 35 1 TRUE 0.29
uterine cancer KRAS_G12D SMO 55 52 Female 0.50 -0.71 1.45 788.72 1.00 1127 51 48 4 TRUE 0.44
colorectal cancer KRAS_G12D SMO 344 71 Sex:overall -0.13 -0.99 0.59 399.52 1.01 2116 335 62 9 TRUE 0.12
non-small cell lung cancer KRAS_G12D SMO 157 75 Sex:overall 0.62 -0.86 1.76 128.77 1.04 3598 151 69 6 TRUE 0.41
uterine cancer KRAS_G12D SMO 55 52 Sex:overall 0.43 -4.08 4.65 1396.57 1.00 1127 51 48 4 TRUE 0.08
colorectal cancer KRAS_G12D RPS6KA4 139 26 Female -0.67 -1.84 0.21 1242.42 1.00 857 137 24 2 FALSE 0.68
colorectal cancer KRAS_G12D RPS6KA4 152 37 Male -0.65 -1.75 0.22 1009.37 1.00 1016 149 34 3 FALSE 0.70
colorectal cancer KRAS_G12D RPS6KA4 291 63 Sex:overall -0.66 -1.91 0.32 1338.13 1.00 1873 286 58 5 FALSE 0.54
colorectal cancer KRAS_G12D KMT2A 144 69 Female -0.16 -0.93 0.39 236.90 1.02 861 138 63 6 FALSE 0.21
colorectal cancer KRAS_G12D KMT2A 159 79 Male 0.03 -0.48 0.59 890.58 1.01 1025 146 66 13 FALSE 0.03
non-small cell lung cancer KRAS_G12D KMT2A 104 64 Female -1.20 -3.19 0.17 1271.57 1.00 1985 103 63 1 FALSE 0.80
non-small cell lung cancer KRAS_G12D KMT2A 48 50 Male -1.09 -3.11 0.38 1272.20 1.00 1455 47 49 1 FALSE 0.65
uterine cancer KRAS_G12D KMT2A 54 109 Female -1.21 -2.84 0.05 1379.02 1.00 991 52 107 2 FALSE 1.01
colorectal cancer KRAS_G12D KMT2A 303 148 Sex:overall -0.07 -0.82 0.63 739.15 1.01 1886 284 129 19 FALSE 0.07
non-small cell lung cancer KRAS_G12D KMT2A 152 114 Sex:overall -1.15 -3.14 0.40 1291.15 1.00 3440 150 112 2 FALSE 0.68
uterine cancer KRAS_G12D KMT2A 54 109 Sex:overall -1.07 -5.46 3.40 1619.79 1.00 991 52 107 2 FALSE 0.22
colorectal cancer KRAS_G12D JAK3 160 33 Female -2.10 -4.62 -0.57 679.11 1.00 962 160 33 0 TRUE 1.09
colorectal cancer KRAS_G12D JAK3 183 30 Male -1.69 -3.57 -0.23 665.56 1.00 1154 181 28 2 TRUE 1.38
non-small cell lung cancer KRAS_G12D JAK3 107 50 Female 0.50 -0.52 1.37 1324.80 1.00 2062 103 46 4 TRUE 0.51
non-small cell lung cancer KRAS_G12D JAK3 50 33 Male 0.50 -0.72 1.55 1459.68 1.00 1528 48 31 2 TRUE 0.42
colorectal cancer KRAS_G12D JAK3 343 63 Sex:overall -1.85 -3.95 -0.36 797.92 1.00 2116 341 61 2 TRUE 1.35
non-small cell lung cancer KRAS_G12D JAK3 157 83 Sex:overall 0.50 -0.71 1.64 1224.95 1.00 3590 151 77 6 TRUE 0.38
non-small cell lung cancer KRAS_G12D PAK7 104 71 Female -2.12 -7.20 0.20 1339.39 1.00 1964 104 71 0 FALSE 0.51
non-small cell lung cancer KRAS_G12D PAK7 47 62 Male 0.70 -0.66 1.72 562.05 1.00 1447 42 57 5 FALSE 0.62
non-small cell lung cancer KRAS_G12D PAK7 151 133 Sex:overall -0.62 -4.15 1.89 1203.19 1.00 3411 146 128 5 FALSE 0.16
non-small cell lung cancer KRAS_G12D STAG2 104 75 Female -0.27 -1.48 0.73 1354.43 1.00 1975 101 72 3 TRUE 0.20
non-small cell lung cancer KRAS_G12D STAG2 48 27 Male -0.19 -1.92 1.30 1330.38 1.00 1478 47 26 1 TRUE 0.09
uterine cancer KRAS_G12D STAG2 56 85 Female 0.38 -0.55 1.19 1657.53 1.00 1004 50 79 6 TRUE 0.42
non-small cell lung cancer KRAS_G12D STAG2 152 102 Sex:overall -0.21 -1.91 1.27 1412.22 1.00 3453 148 98 4 TRUE 0.10
uterine cancer KRAS_G12D STAG2 56 85 Sex:overall 0.36 -3.96 4.80 1601.75 1.00 1004 50 79 6 TRUE 0.06
colorectal cancer KRAS_G12D BRCA2 144 75 Female -0.88 -1.67 -0.22 1462.30 1.00 849 140 71 4 TRUE 1.79
colorectal cancer KRAS_G12D BRCA2 159 115 Male -0.73 -1.39 -0.08 1106.05 1.00 1018 150 106 9 TRUE 1.60
non-small cell lung cancer KRAS_G12D BRCA2 104 72 Female -0.75 -2.22 0.38 289.76 1.01 1982 102 70 2 TRUE 0.57
non-small cell lung cancer KRAS_G12D BRCA2 48 63 Male -0.80 -2.48 0.44 425.93 1.01 1443 47 62 1 TRUE 0.54
uterine cancer KRAS_G12D BRCA2 54 134 Female -0.98 -2.35 0.11 1507.56 1.00 980 51 131 3 TRUE 0.91
colorectal cancer KRAS_G12D BRCA2 303 190 Sex:overall -0.81 -1.65 -0.03 1502.61 1.00 1867 290 177 13 TRUE 1.34
non-small cell lung cancer KRAS_G12D BRCA2 152 135 Sex:overall -0.77 -2.50 0.57 437.60 1.01 3425 149 132 3 TRUE 0.50
uterine cancer KRAS_G12D BRCA2 54 134 Sex:overall -0.93 -5.90 3.57 1505.19 1.00 980 51 131 3 TRUE 0.17
colorectal cancer KRAS_G12D NOTCH3 144 88 Female -0.74 -1.38 -0.16 640.45 1.00 841 137 81 7 TRUE 1.70
colorectal cancer KRAS_G12D NOTCH3 158 112 Male -0.78 -1.41 -0.22 529.66 1.01 997 151 105 7 TRUE 1.91
non-small cell lung cancer KRAS_G12D NOTCH3 104 64 Female -0.72 -2.17 0.44 1085.36 1.00 1985 102 62 2 TRUE 0.54
non-small cell lung cancer KRAS_G12D NOTCH3 48 64 Male -0.80 -2.31 0.49 1141.63 1.00 1444 47 63 1 TRUE 0.54
uterine cancer KRAS_G12D NOTCH3 53 91 Female -1.99 -4.81 -0.20 1433.88 1.00 987 52 90 1 TRUE 1.04
colorectal cancer KRAS_G12D NOTCH3 302 200 Sex:overall -0.75 -1.41 -0.12 808.22 1.00 1838 288 186 14 TRUE 1.50
non-small cell lung cancer KRAS_G12D NOTCH3 152 128 Sex:overall -0.76 -2.38 0.67 1087.49 1.00 3429 149 125 3 TRUE 0.47
uterine cancer KRAS_G12D NOTCH3 53 91 Sex:overall -1.59 -6.03 3.43 1432.52 1.00 987 52 90 1 TRUE 0.32
colorectal cancer KRAS_G12D NOTCH4 140 45 Female -0.19 -0.86 0.46 1522.46 1.00 841 134 39 6 TRUE 0.24
colorectal cancer KRAS_G12D NOTCH4 153 77 Male -0.20 -0.82 0.41 1609.33 1.00 992 145 69 8 TRUE 0.30
non-small cell lung cancer KRAS_G12D NOTCH4 104 82 Female -0.86 -2.58 0.31 1233.74 1.00 1953 103 81 1 TRUE 0.62
non-small cell lung cancer KRAS_G12D NOTCH4 47 57 Male -0.10 -1.48 1.15 1257.65 1.00 1447 44 54 3 TRUE 0.06
colorectal cancer KRAS_G12D NOTCH4 293 122 Sex:overall -0.20 -1.04 0.65 1492.10 1.00 1833 279 108 14 TRUE 0.21
non-small cell lung cancer KRAS_G12D NOTCH4 151 139 Sex:overall -0.46 -2.11 1.07 1432.77 1.00 3400 147 135 4 TRUE 0.24
colorectal cancer KRAS_G12D FGFR3 160 25 Female -1.39 -5.32 0.16 572.42 1.01 967 160 25 0 TRUE 0.45
colorectal cancer KRAS_G12D FGFR3 183 35 Male -0.44 -1.50 0.56 598.14 1.01 1155 178 30 5 TRUE 0.38
colorectal cancer KRAS_G12D FGFR3 343 60 Sex:overall -0.86 -3.14 0.57 846.51 1.00 2122 338 55 5 TRUE 0.44
non-small cell lung cancer KRAS_G12D MAP3K13 104 30 Female -1.23 -4.17 0.68 1207.27 1.00 2003 103 29 1 FALSE 0.49
non-small cell lung cancer KRAS_G12D MAP3K13 47 22 Male -1.48 -5.10 0.57 1170.48 1.00 1476 47 22 0 FALSE 0.52
non-small cell lung cancer KRAS_G12D MAP3K13 151 52 Sex:overall -1.32 -4.56 0.82 1254.29 1.00 3479 150 51 1 FALSE 0.50
colorectal cancer KRAS_G12D IGF1R 144 31 Female -0.36 -1.36 0.36 66.73 1.04 881 141 28 3 TRUE 0.36
colorectal cancer KRAS_G12D IGF1R 158 49 Male -0.30 -1.18 0.35 73.31 1.04 1039 153 44 5 TRUE 0.33
non-small cell lung cancer KRAS_G12D IGF1R 104 31 Female -1.30 -3.83 0.62 854.69 1.00 2014 103 30 1 TRUE 0.59
non-small cell lung cancer KRAS_G12D IGF1R 48 23 Male -1.53 -4.75 0.57 1053.63 1.00 1479 48 23 0 TRUE 0.59
colorectal cancer KRAS_G12D IGF1R 302 80 Sex:overall -0.32 -1.34 0.46 82.58 1.03 1920 294 72 8 TRUE 0.31
non-small cell lung cancer KRAS_G12D IGF1R 152 54 Sex:overall -1.38 -4.21 0.72 912.73 1.00 3493 151 53 1 TRUE 0.57
cancer of unknown primary KRAS_G12D KEAP1 35 35 Female -5.46 -12.34 -1.05 515.17 1.01 356 35 35 0 FALSE 1.17
cancer of unknown primary KRAS_G12D KEAP1 19 33 Male -5.42 -12.32 -0.90 522.32 1.01 336 19 33 0 FALSE 1.15
non-small cell lung cancer KRAS_G12D KEAP1 104 248 Female 0.09 -0.48 0.63 1184.54 1.00 1817 90 234 14 FALSE 0.13
non-small cell lung cancer KRAS_G12D KEAP1 48 290 Male -0.23 -0.99 0.43 1547.28 1.00 1234 41 283 7 FALSE 0.28
cancer of unknown primary KRAS_G12D KEAP1 54 68 Sex:overall -5.34 -12.33 -0.93 518.67 1.01 692 54 68 0 FALSE 1.13
non-small cell lung cancer KRAS_G12D KEAP1 152 538 Sex:overall -0.07 -1.16 1.05 1336.91 1.00 3051 131 517 21 FALSE 0.05
colorectal cancer KRAS_G12D KDM5C 146 41 Female 0.54 -0.10 1.23 1200.47 1.00 884 136 31 10 FALSE 0.92
colorectal cancer KRAS_G12D KDM5C 158 28 Male 0.12 -0.89 0.92 1304.32 1.01 1052 155 25 3 FALSE 0.10
non-small cell lung cancer KRAS_G12D KDM5C 105 71 Female 0.05 -0.97 0.92 1343.45 1.00 1979 101 67 4 FALSE 0.03
non-small cell lung cancer KRAS_G12D KDM5C 48 35 Male -0.06 -1.54 1.12 1380.77 1.00 1469 47 34 1 FALSE 0.03
uterine cancer KRAS_G12D KDM5C 53 67 Female -0.20 -1.46 0.86 265.30 1.01 1011 50 64 3 FALSE 0.12
colorectal cancer KRAS_G12D KDM5C 304 69 Sex:overall 0.35 -0.86 1.39 1239.11 1.00 1936 291 56 13 FALSE 0.27
non-small cell lung cancer KRAS_G12D KDM5C 153 106 Sex:overall 0.01 -1.37 1.30 1312.62 1.00 3448 148 101 5 FALSE 0.00
uterine cancer KRAS_G12D KDM5C 53 67 Sex:overall -0.16 -4.54 4.60 1405.00 1.00 1011 50 64 3 FALSE 0.03
cancer of unknown primary KRAS_G12D CDKN2A 35 34 Female -0.05 -1.18 0.96 817.67 1.00 365 32 31 3 TRUE 0.03
cancer of unknown primary KRAS_G12D CDKN2A 19 37 Male -0.04 -1.25 1.12 748.58 1.00 340 17 35 2 TRUE 0.02
non-small cell lung cancer KRAS_G12D CDKN2A 107 139 Female -0.24 -1.07 0.46 1359.17 1.00 1985 101 133 6 TRUE 0.27
non-small cell lung cancer KRAS_G12D CDKN2A 50 137 Male -0.34 -1.38 0.50 1449.21 1.00 1430 47 134 3 TRUE 0.33
pancreatic cancer KRAS_G12D CDKN2A 254 134 Female 0.51 0.22 0.81 889.21 1.00 437 196 76 58 TRUE 3.25
pancreatic cancer KRAS_G12D CDKN2A 268 160 Male 0.51 0.24 0.80 1065.45 1.00 480 202 94 66 TRUE 3.35
cancer of unknown primary KRAS_G12D CDKN2A 54 71 Sex:overall -0.02 -1.26 1.21 710.42 1.00 705 49 66 5 TRUE 0.01
non-small cell lung cancer KRAS_G12D CDKN2A 157 276 Sex:overall -0.27 -1.43 0.87 1482.97 1.00 3415 148 267 9 TRUE 0.20
pancreatic cancer KRAS_G12D CDKN2A 522 294 Sex:overall 0.50 0.15 0.87 1337.21 1.00 917 398 170 124 TRUE 1.83
colorectal cancer KRAS_G12D EPHB1 144 32 Female -0.63 -1.67 0.39 462.28 1.00 879 140 28 4 FALSE 0.66
colorectal cancer KRAS_G12D EPHB1 158 50 Male -0.86 -1.96 0.20 403.17 1.00 1030 156 48 2 FALSE 1.00
non-small cell lung cancer KRAS_G12D EPHB1 104 81 Female -0.83 -2.27 0.35 858.87 1.00 1975 101 78 3 FALSE 0.67
non-small cell lung cancer KRAS_G12D EPHB1 48 77 Male -1.51 -4.31 0.04 1366.55 1.00 1429 48 77 0 FALSE 0.71
colorectal cancer KRAS_G12D EPHB1 302 82 Sex:overall -0.75 -1.90 0.30 585.37 1.00 1909 296 76 6 FALSE 0.73
non-small cell lung cancer KRAS_G12D EPHB1 152 158 Sex:overall -1.18 -3.31 0.43 1432.79 1.00 3404 149 155 3 FALSE 0.68
colorectal cancer KRAS_G12D IRS2 144 29 Female -0.22 -1.16 0.58 1360.92 1.00 884 141 26 3 FALSE 0.20
colorectal cancer KRAS_G12D IRS2 158 58 Male -0.03 -0.84 0.65 1332.61 1.00 1031 150 50 8 FALSE 0.03
non-small cell lung cancer KRAS_G12D IRS2 104 42 Female -5.09 -11.88 -1.03 495.31 1.01 2003 104 42 0 FALSE 1.20
non-small cell lung cancer KRAS_G12D IRS2 48 42 Male -5.07 -11.59 -0.96 529.28 1.01 1461 48 42 0 FALSE 1.19
uterine cancer KRAS_G12D IRS2 53 74 Female -1.77 -4.72 0.12 1247.03 1.00 997 52 73 1 FALSE 0.84
colorectal cancer KRAS_G12D IRS2 302 87 Sex:overall -0.12 -1.23 0.97 1271.67 1.00 1915 291 76 11 FALSE 0.08
non-small cell lung cancer KRAS_G12D IRS2 152 84 Sex:overall -4.97 -11.46 -0.89 608.11 1.01 3464 152 84 0 FALSE 1.16
uterine cancer KRAS_G12D IRS2 53 74 Sex:overall -1.55 -6.26 3.47 1437.94 1.00 997 52 73 1 FALSE 0.28
colorectal cancer KRAS_G12D FANCA 144 31 Female -0.22 -1.10 0.57 604.32 1.01 880 141 28 3 TRUE 0.20
colorectal cancer KRAS_G12D FANCA 158 34 Male -0.13 -1.02 0.71 440.21 1.01 1051 153 29 5 TRUE 0.12
non-small cell lung cancer KRAS_G12D FANCA 104 39 Female 0.42 -0.82 1.45 1206.68 1.00 2009 100 35 4 TRUE 0.33
non-small cell lung cancer KRAS_G12D FANCA 48 30 Male -0.40 -4.04 1.17 1101.71 1.00 1474 48 30 0 TRUE 0.12
colorectal cancer KRAS_G12D FANCA 302 65 Sex:overall -0.18 -1.12 0.71 674.99 1.01 1931 294 57 8 TRUE 0.15
non-small cell lung cancer KRAS_G12D FANCA 152 69 Sex:overall 0.03 -2.35 1.53 1373.80 1.00 3483 148 65 4 TRUE 0.01
non-small cell lung cancer KRAS_G12D IL7R 104 51 Female -0.84 -2.69 0.49 1149.80 1.00 1998 102 49 2 FALSE 0.52
non-small cell lung cancer KRAS_G12D IL7R 48 40 Male -1.30 -4.22 0.36 895.45 1.01 1467 48 40 0 FALSE 0.57
non-small cell lung cancer KRAS_G12D IL7R 152 91 Sex:overall -1.06 -3.49 0.55 1311.25 1.01 3465 150 89 2 FALSE 0.52
uterine cancer KRAS_G12D PPP2R1A 53 159 Female -1.19 -2.56 -0.13 1422.27 1.00 913 50 156 3 FALSE 1.18
uterine cancer KRAS_G12D PPP2R1A 53 159 Sex:overall -1.00 -5.29 4.09 1399.70 1.00 913 50 156 3 FALSE 0.20
colorectal cancer KRAS_G12D PIK3CB 139 24 Female -1.81 -3.54 -0.40 1324.65 1.00 859 138 23 1 FALSE 1.55
colorectal cancer KRAS_G12D PIK3CB 152 44 Male -1.90 -3.69 -0.52 1255.59 1.00 1018 151 43 1 FALSE 1.65
colorectal cancer KRAS_G12D PIK3CB 291 68 Sex:overall -1.84 -3.66 -0.32 1292.32 1.00 1877 289 66 2 FALSE 1.44
colorectal cancer KRAS_G12D ERBB3 145 52 Female -0.38 -0.91 0.44 2.02 1.90 868 138 45 7 TRUE 0.39
colorectal cancer KRAS_G12D ERBB3 158 70 Male -0.39 -0.93 0.44 1.99 1.94 1020 150 62 8 TRUE 0.41
uterine cancer KRAS_G12D ERBB3 53 80 Female -0.37 -1.74 0.70 1648.91 1.00 987 50 77 3 TRUE 0.26
colorectal cancer KRAS_G12D ERBB3 303 122 Sex:overall -0.39 -0.94 0.51 2.13 1.77 1888 288 107 15 TRUE 0.37
uterine cancer KRAS_G12D ERBB3 53 80 Sex:overall -0.25 -4.39 3.83 1281.35 1.00 987 50 77 3 TRUE 0.05
colorectal cancer KRAS_G12D SMAD4 162 170 Female 0.02 -0.37 0.40 877.77 1.00 862 135 143 27 TRUE 0.04
colorectal cancer KRAS_G12D SMAD4 185 190 Male -0.10 -0.50 0.28 658.46 1.00 1027 164 169 21 TRUE 0.20
non-small cell lung cancer KRAS_G12D SMAD4 107 74 Female -0.57 -1.95 0.55 1205.28 1.00 2039 104 71 3 TRUE 0.43
non-small cell lung cancer KRAS_G12D SMAD4 50 42 Male -1.14 -4.25 0.44 1190.75 1.00 1516 50 42 0 TRUE 0.42
pancreatic cancer KRAS_G12D SMAD4 249 136 Female 0.02 -0.29 0.33 1032.08 1.00 421 203 90 46 TRUE 0.04
pancreatic cancer KRAS_G12D SMAD4 266 139 Male -0.02 -0.35 0.28 924.61 1.00 476 223 96 43 TRUE 0.06
colorectal cancer KRAS_G12D SMAD4 347 360 Sex:overall -0.03 -0.48 0.42 1204.47 1.00 1889 299 312 48 TRUE 0.04
non-small cell lung cancer KRAS_G12D SMAD4 157 116 Sex:overall -0.82 -2.97 0.70 1095.81 1.00 3555 154 113 3 TRUE 0.41
pancreatic cancer KRAS_G12D SMAD4 515 275 Sex:overall 0.00 -0.38 0.36 1092.40 1.00 897 426 186 89 TRUE 0.01
colorectal cancer KRAS_G12D ATM 161 100 Female -0.32 -0.81 0.16 1331.99 1.00 919 150 89 11 TRUE 0.72
colorectal cancer KRAS_G12D ATM 186 131 Male -0.34 -0.81 0.09 1210.86 1.00 1097 173 118 13 TRUE 0.83
non-small cell lung cancer KRAS_G12D ATM 109 174 Female 0.34 -0.25 0.91 1308.86 1.00 1966 96 161 13 TRUE 0.60
non-small cell lung cancer KRAS_G12D ATM 50 114 Male -0.15 -1.44 0.68 1137.10 1.00 1456 48 112 2 TRUE 0.11
uterine cancer KRAS_G12D ATM 57 166 Female -0.12 -0.96 0.63 1634.60 1.00 1076 50 159 7 TRUE 0.11
colorectal cancer KRAS_G12D ATM 347 231 Sex:overall -0.33 -0.87 0.18 1402.20 1.00 2016 323 207 24 TRUE 0.69
non-small cell lung cancer KRAS_G12D ATM 159 288 Sex:overall 0.11 -1.13 1.03 1487.50 1.00 3422 144 273 15 TRUE 0.07
uterine cancer KRAS_G12D ATM 57 166 Sex:overall -0.07 -4.47 4.12 1387.10 1.00 1076 50 159 7 TRUE 0.01
cancer of unknown primary KRAS_G12D RB1 36 36 Female -0.25 -1.53 0.82 1163.18 1.00 366 33 33 3 TRUE 0.17
cancer of unknown primary KRAS_G12D RB1 19 35 Male -0.42 -1.99 0.77 1420.14 1.00 341 18 34 1 TRUE 0.27
colorectal cancer KRAS_G12D RB1 160 23 Female -0.93 -2.26 0.12 1279.03 1.00 973 159 22 1 TRUE 0.88
colorectal cancer KRAS_G12D RB1 184 45 Male -0.74 -1.85 0.18 1110.96 1.00 1149 180 41 4 TRUE 0.82
non-small cell lung cancer KRAS_G12D RB1 107 107 Female -0.37 -1.52 0.56 1379.57 1.00 2009 102 102 5 TRUE 0.32
non-small cell lung cancer KRAS_G12D RB1 50 116 Male -1.84 -5.74 -0.12 1278.74 1.00 1443 50 116 0 TRUE 0.68
uterine cancer KRAS_G12D RB1 55 94 Female -1.94 -4.49 -0.22 1402.34 1.00 1102 54 93 1 TRUE 1.08
cancer of unknown primary KRAS_G12D RB1 55 71 Sex:overall -0.32 -1.87 1.02 1546.25 1.00 707 51 67 4 TRUE 0.18
colorectal cancer KRAS_G12D RB1 344 68 Sex:overall -0.83 -2.14 0.30 1271.01 1.00 2122 339 63 5 TRUE 0.71
non-small cell lung cancer KRAS_G12D RB1 157 223 Sex:overall -1.02 -3.57 0.80 1342.04 1.00 3452 152 218 5 TRUE 0.44
uterine cancer KRAS_G12D RB1 55 94 Sex:overall -1.58 -5.82 3.46 1237.63 1.00 1102 54 93 1 TRUE 0.32
cancer of unknown primary KRAS_G12D KMT2D 35 63 Female 0.35 -0.56 1.22 1162.34 1.00 346 27 55 8 FALSE 0.35
cancer of unknown primary KRAS_G12D KMT2D 19 62 Male -1.61 -6.15 0.23 1203.12 1.00 323 19 62 0 FALSE 0.45
colorectal cancer KRAS_G12D KMT2D 150 187 Female -0.54 -1.16 -0.08 1097.20 1.00 804 137 174 13 FALSE 1.30
colorectal cancer KRAS_G12D KMT2D 166 201 Male -0.24 -0.68 0.23 1022.73 1.00 966 141 176 25 FALSE 0.52
non-small cell lung cancer KRAS_G12D KMT2D 104 136 Female -1.71 -3.49 -0.49 1613.21 1.00 1920 103 135 1 FALSE 1.64
non-small cell lung cancer KRAS_G12D KMT2D 49 192 Male -1.16 -2.50 -0.06 1574.81 1.00 1347 46 189 3 FALSE 1.21
pancreatic cancer KRAS_G12D KMT2D 238 26 Female -0.33 -1.41 0.55 951.46 1.01 469 233 21 5 FALSE 0.29
pancreatic cancer KRAS_G12D KMT2D 264 40 Male 0.57 -0.08 1.21 1360.98 1.00 533 244 20 20 FALSE 1.03
uterine cancer KRAS_G12D KMT2D 57 264 Female -0.20 -0.87 0.42 1543.20 1.00 890 46 253 11 FALSE 0.25
cancer of unknown primary KRAS_G12D KMT2D 54 125 Sex:overall -0.60 -3.91 1.35 1384.51 1.00 669 46 117 8 FALSE 0.20
colorectal cancer KRAS_G12D KMT2D 316 388 Sex:overall -0.40 -1.03 0.21 1517.60 1.00 1770 278 350 38 FALSE 0.63
non-small cell lung cancer KRAS_G12D KMT2D 153 328 Sex:overall -1.37 -3.05 0.22 1497.69 1.00 3267 149 324 4 FALSE 0.93
pancreatic cancer KRAS_G12D KMT2D 502 66 Sex:overall 0.13 -1.27 1.26 1506.67 1.00 1002 477 41 25 FALSE 0.07
uterine cancer KRAS_G12D KMT2D 57 264 Sex:overall -0.13 -4.41 4.28 1373.92 1.00 890 46 253 11 FALSE 0.02
colorectal cancer KRAS_G12D TSC2 145 62 Female -0.17 -0.96 0.46 1311.01 1.00 862 139 56 6 TRUE 0.19
colorectal cancer KRAS_G12D TSC2 160 53 Male 0.06 -0.61 0.75 1349.67 1.00 1037 151 44 9 TRUE 0.07
non-small cell lung cancer KRAS_G12D TSC2 104 46 Female -1.55 -4.15 0.27 1082.34 1.00 2001 103 45 1 TRUE 0.76
non-small cell lung cancer KRAS_G12D TSC2 48 26 Male -1.81 -5.24 0.37 1257.08 1.00 1477 48 26 0 TRUE 0.70
uterine cancer KRAS_G12D TSC2 56 74 Female 0.70 -0.23 1.48 1471.39 1.00 1004 49 67 7 TRUE 0.95
colorectal cancer KRAS_G12D TSC2 305 115 Sex:overall -0.03 -0.90 0.81 1450.05 1.00 1899 290 100 15 TRUE 0.03
non-small cell lung cancer KRAS_G12D TSC2 152 72 Sex:overall -1.65 -4.69 0.43 926.53 1.00 3478 151 71 1 TRUE 0.71
uterine cancer KRAS_G12D TSC2 56 74 Sex:overall 0.57 -3.61 4.72 1394.54 1.00 1004 49 67 7 TRUE 0.11
cancer of unknown primary KRAS_G12D APC 38 44 Female 0.66 -0.24 1.47 1510.17 1.00 365 32 38 6 TRUE 0.91
cancer of unknown primary KRAS_G12D APC 20 22 Male 0.84 -0.32 1.92 1416.33 1.00 354 17 19 3 TRUE 0.87
colorectal cancer KRAS_G12D APC 230 1110 Female 0.21 -0.08 0.55 853.87 1.00 373 51 931 179 TRUE 0.71
colorectal cancer KRAS_G12D APC 260 1428 Male -0.10 -0.41 0.18 731.58 1.00 394 73 1241 187 TRUE 0.28
non-small cell lung cancer KRAS_G12D APC 107 85 Female -0.03 -0.95 0.78 1282.43 1.00 2027 103 81 4 TRUE 0.03
non-small cell lung cancer KRAS_G12D APC 50 72 Male 0.07 -1.00 1.02 1383.18 1.00 1496 47 69 3 TRUE 0.05
uterine cancer KRAS_G12D APC 58 127 Female -0.01 -0.92 0.79 667.95 1.01 1106 52 121 6 TRUE 0.01
cancer of unknown primary KRAS_G12D APC 58 66 Sex:overall 0.73 -0.57 2.01 1435.70 1.00 719 49 57 9 TRUE 0.57
colorectal cancer KRAS_G12D APC 490 2538 Sex:overall 0.06 -0.56 0.70 1453.83 1.00 767 124 2172 366 TRUE 0.07
non-small cell lung cancer KRAS_G12D APC 157 157 Sex:overall 0.02 -1.22 1.16 1498.94 1.00 3523 150 150 7 TRUE 0.01
uterine cancer KRAS_G12D APC 58 127 Sex:overall -0.01 -4.36 3.95 1269.68 1.00 1106 52 121 6 TRUE 0.00
colorectal cancer KRAS_G12D ERBB2 160 38 Female -0.64 -1.62 0.16 1404.71 1.00 959 157 35 3 TRUE 0.81
colorectal cancer KRAS_G12D ERBB2 183 66 Male -0.57 -1.37 0.11 1180.90 1.00 1127 177 60 6 TRUE 0.88
non-small cell lung cancer KRAS_G12D ERBB2 107 76 Female -2.45 -5.68 -0.48 1413.02 1.00 2034 107 76 0 TRUE 1.08
non-small cell lung cancer KRAS_G12D ERBB2 50 53 Male -1.91 -4.69 0.09 1454.73 1.00 1507 49 52 1 TRUE 0.95
uterine cancer KRAS_G12D ERBB2 56 58 Female -0.57 -2.52 0.81 993.47 1.00 1118 54 56 2 TRUE 0.32
colorectal cancer KRAS_G12D ERBB2 343 104 Sex:overall -0.60 -1.64 0.24 1338.82 1.00 2086 334 95 9 TRUE 0.70
non-small cell lung cancer KRAS_G12D ERBB2 157 129 Sex:overall -2.13 -4.89 -0.05 1500.62 1.00 3541 156 128 1 TRUE 1.05
uterine cancer KRAS_G12D ERBB2 56 58 Sex:overall -0.51 -4.76 4.00 1372.44 1.00 1118 54 56 2 TRUE 0.09
colorectal cancer KRAS_G12D JAK1 146 29 Female -0.29 -1.11 0.53 1066.35 1.00 884 142 25 4 TRUE 0.30
colorectal cancer KRAS_G12D JAK1 159 46 Male -0.35 -1.23 0.41 1189.77 1.00 1042 155 42 4 TRUE 0.39
non-small cell lung cancer KRAS_G12D JAK1 104 19 Female -5.01 -12.16 -0.48 1180.97 1.00 2026 104 19 0 TRUE 1.00
non-small cell lung cancer KRAS_G12D JAK1 48 33 Male -5.00 -11.98 -0.47 1268.67 1.00 1470 48 33 0 TRUE 1.00
uterine cancer KRAS_G12D JAK1 57 145 Female 0.75 0.07 1.38 1514.20 1.00 962 44 132 13 TRUE 1.61
colorectal cancer KRAS_G12D JAK1 305 75 Sex:overall -0.32 -1.30 0.55 1312.72 1.00 1926 297 67 8 TRUE 0.31
non-small cell lung cancer KRAS_G12D JAK1 152 52 Sex:overall -4.88 -11.53 -0.28 1257.98 1.00 3496 152 52 0 TRUE 0.97
uterine cancer KRAS_G12D JAK1 57 145 Sex:overall 0.59 -4.54 5.01 1465.00 1.00 962 44 132 13 TRUE 0.11
uterine cancer KRAS_G12D CCND1 53 69 Female 0.61 -0.38 1.49 1308.69 1.00 993 47 63 6 TRUE 0.75
uterine cancer KRAS_G12D CCND1 53 69 Sex:overall 0.44 -4.21 4.65 1096.84 1.00 993 47 63 6 TRUE 0.08
colorectal cancer KRAS_G12D ARID2 144 54 Female -0.27 -1.03 0.34 407.33 1.00 862 139 49 5 FALSE 0.35
colorectal cancer KRAS_G12D ARID2 158 56 Male -0.20 -0.88 0.38 513.65 1.00 1036 151 49 7 FALSE 0.27
non-small cell lung cancer KRAS_G12D ARID2 104 88 Female -0.12 -1.08 0.78 1290.40 1.00 1962 99 83 5 FALSE 0.09
non-small cell lung cancer KRAS_G12D ARID2 48 94 Male -0.65 -2.23 0.48 1445.21 1.00 1422 47 93 1 FALSE 0.47
uterine cancer KRAS_G12D ARID2 56 71 Female 0.56 -0.38 1.41 1232.84 1.00 1008 50 65 6 FALSE 0.65
colorectal cancer KRAS_G12D ARID2 302 110 Sex:overall -0.24 -1.05 0.43 567.93 1.00 1898 290 98 12 FALSE 0.27
non-small cell lung cancer KRAS_G12D ARID2 152 182 Sex:overall -0.37 -1.86 0.98 1334.81 1.00 3384 146 176 6 FALSE 0.22
uterine cancer KRAS_G12D ARID2 56 71 Sex:overall 0.46 -3.52 4.58 1598.04 1.00 1008 50 65 6 FALSE 0.09
colorectal cancer KRAS_G12D SOX17 139 52 Female 0.22 -0.48 0.82 1483.57 1.00 837 131 44 8 FALSE 0.29
colorectal cancer KRAS_G12D SOX17 153 46 Male 0.25 -0.42 0.87 1455.52 1.00 1015 145 38 8 FALSE 0.37
non-small cell lung cancer KRAS_G12D SOX17 104 34 Female -0.40 -2.30 1.00 1306.74 1.00 2001 102 32 2 FALSE 0.20
non-small cell lung cancer KRAS_G12D SOX17 47 27 Male -0.91 -3.93 0.77 1310.58 1.00 1471 47 27 0 FALSE 0.32
colorectal cancer KRAS_G12D SOX17 292 98 Sex:overall 0.23 -0.57 0.92 1386.24 1.00 1852 276 82 16 FALSE 0.26
non-small cell lung cancer KRAS_G12D SOX17 151 61 Sex:overall -0.64 -3.15 1.05 1364.77 1.00 3472 149 59 2 FALSE 0.26
colorectal cancer KRAS_G12D MTOR 145 75 Female -0.34 -1.10 0.28 821.01 1.00 849 139 69 6 TRUE 0.48
colorectal cancer KRAS_G12D MTOR 160 65 Male 0.01 -0.62 0.72 678.11 1.00 1028 149 54 11 TRUE 0.01
non-small cell lung cancer KRAS_G12D MTOR 104 64 Female -1.78 -5.28 -0.02 1036.94 1.00 1980 104 64 0 TRUE 0.70
non-small cell lung cancer KRAS_G12D MTOR 48 51 Male -0.72 -2.60 0.84 940.93 1.00 1455 46 49 2 TRUE 0.39
uterine cancer KRAS_G12D MTOR 54 90 Female 0.51 -0.40 1.33 609.59 1.01 991 47 83 7 TRUE 0.60
colorectal cancer KRAS_G12D MTOR 305 140 Sex:overall -0.16 -0.98 0.63 928.29 1.00 1877 288 123 17 TRUE 0.15
non-small cell lung cancer KRAS_G12D MTOR 152 115 Sex:overall -1.25 -3.75 0.74 1224.40 1.00 3435 150 113 2 TRUE 0.58
uterine cancer KRAS_G12D MTOR 54 90 Sex:overall 0.34 -4.35 4.60 1366.23 1.00 991 47 83 7 TRUE 0.06
non-small cell lung cancer KRAS_G12D RFWD2 104 30 Female -0.29 -2.11 1.13 1247.42 1.00 2003 102 28 2 FALSE 0.14
non-small cell lung cancer KRAS_G12D RFWD2 47 27 Male -0.76 -3.66 1.00 971.14 1.00 1471 47 27 0 FALSE 0.28
non-small cell lung cancer KRAS_G12D RFWD2 151 57 Sex:overall -0.50 -2.76 1.24 1324.49 1.00 3474 149 55 2 FALSE 0.20
colorectal cancer KRAS_G12D IRS1 139 43 Female -0.77 -1.66 0.04 24.66 1.09 841 137 41 2 FALSE 0.90
colorectal cancer KRAS_G12D IRS1 153 54 Male -0.63 -1.43 0.17 17.34 1.14 1008 147 48 6 FALSE 0.75
non-small cell lung cancer KRAS_G12D IRS1 104 38 Female -5.10 -11.84 -0.85 1192.84 1.00 1995 104 38 0 FALSE 1.08
non-small cell lung cancer KRAS_G12D IRS1 47 35 Male -5.12 -11.93 -0.59 1161.21 1.00 1464 47 35 0 FALSE 1.05
colorectal cancer KRAS_G12D IRS1 292 97 Sex:overall -0.69 -1.50 0.20 22.39 1.10 1849 284 89 8 FALSE 0.75
non-small cell lung cancer KRAS_G12D IRS1 151 73 Sex:overall -5.01 -11.71 -0.59 1214.13 1.00 3459 151 73 0 FALSE 1.05
cancer of unknown primary KRAS_G12D NOTCH1 36 24 Female -0.70 -2.53 0.78 410.87 1.01 375 34 22 2 TRUE 0.41
cancer of unknown primary KRAS_G12D NOTCH1 19 27 Male -1.24 -4.15 0.51 870.51 1.00 348 19 27 0 TRUE 0.48
colorectal cancer KRAS_G12D NOTCH1 163 85 Female -0.29 -0.88 0.32 870.72 1.00 938 151 73 12 TRUE 0.49
colorectal cancer KRAS_G12D NOTCH1 184 87 Male -0.57 -1.41 0.00 935.32 1.00 1117 179 82 5 TRUE 0.98
non-small cell lung cancer KRAS_G12D NOTCH1 107 64 Female -0.48 -1.78 0.56 1179.87 1.00 2047 105 62 2 TRUE 0.36
non-small cell lung cancer KRAS_G12D NOTCH1 50 66 Male -0.32 -1.66 0.75 1451.06 1.00 1500 48 64 2 TRUE 0.22
uterine cancer KRAS_G12D NOTCH1 55 90 Female -0.47 -1.85 0.60 1053.33 1.00 1107 52 87 3 TRUE 0.34
cancer of unknown primary KRAS_G12D NOTCH1 55 51 Sex:overall -0.95 -3.23 0.83 858.15 1.00 723 53 49 2 TRUE 0.42
colorectal cancer KRAS_G12D NOTCH1 347 172 Sex:overall -0.43 -1.21 0.29 1200.95 1.00 2055 330 155 17 TRUE 0.53
non-small cell lung cancer KRAS_G12D NOTCH1 157 130 Sex:overall -0.38 -1.85 0.86 1534.23 1.00 3547 153 126 4 TRUE 0.23
uterine cancer KRAS_G12D NOTCH1 55 90 Sex:overall -0.35 -4.43 4.44 1663.78 1.00 1107 52 87 3 TRUE 0.06
colorectal cancer KRAS_G12D NTRK1 144 24 Female -0.38 -1.49 0.49 1018.09 1.00 886 142 22 2 TRUE 0.34
colorectal cancer KRAS_G12D NTRK1 159 40 Male -0.25 -1.21 0.58 1114.06 1.00 1041 154 35 5 TRUE 0.24
non-small cell lung cancer KRAS_G12D NTRK1 104 38 Female -1.61 -4.26 0.36 1467.00 1.00 2007 103 37 1 TRUE 0.72
non-small cell lung cancer KRAS_G12D NTRK1 48 50 Male -2.09 -5.71 0.13 1470.69 1.00 1453 48 50 0 TRUE 0.75
colorectal cancer KRAS_G12D NTRK1 303 64 Sex:overall -0.31 -1.37 0.63 1139.31 1.00 1927 296 57 7 TRUE 0.25
non-small cell lung cancer KRAS_G12D NTRK1 152 88 Sex:overall -1.82 -4.85 0.34 1447.28 1.00 3460 151 87 1 TRUE 0.74
non-small cell lung cancer KRAS_G12D INPP4A 104 21 Female -4.82 -11.98 -0.48 1267.14 1.00 2010 104 21 0 FALSE 0.92
non-small cell lung cancer KRAS_G12D INPP4A 47 32 Male -4.84 -11.62 -0.40 1223.19 1.00 1467 47 32 0 FALSE 0.96
non-small cell lung cancer KRAS_G12D INPP4A 151 53 Sex:overall -4.71 -11.70 -0.30 1250.46 1.00 3477 151 53 0 FALSE 0.95
colorectal cancer KRAS_G12D CASP8 139 38 Female -0.22 -0.98 0.44 1038.48 1.00 848 135 34 4 FALSE 0.26
colorectal cancer KRAS_G12D CASP8 153 58 Male -0.15 -0.82 0.49 881.19 1.01 1008 146 51 7 FALSE 0.18
colorectal cancer KRAS_G12D CASP8 292 96 Sex:overall -0.19 -0.98 0.53 1088.51 1.00 1856 281 85 11 FALSE 0.20
colorectal cancer KRAS_G12D SETD2 145 34 Female -0.83 -1.93 0.15 1451.99 1.00 879 142 31 3 FALSE 0.93
colorectal cancer KRAS_G12D SETD2 159 79 Male -1.01 -1.98 -0.15 1512.32 1.00 1016 155 75 4 FALSE 1.55
non-small cell lung cancer KRAS_G12D SETD2 105 131 Female -0.18 -1.03 0.54 1181.18 1.00 1939 100 126 5 FALSE 0.19
non-small cell lung cancer KRAS_G12D SETD2 49 94 Male -0.01 -0.88 0.85 1427.11 1.00 1422 45 90 4 FALSE 0.01
uterine cancer KRAS_G12D SETD2 55 89 Female -0.20 -1.41 0.73 1393.64 1.00 993 51 85 4 FALSE 0.14
colorectal cancer KRAS_G12D SETD2 304 113 Sex:overall -0.90 -2.12 0.33 1182.56 1.00 1895 297 106 7 FALSE 0.83
non-small cell lung cancer KRAS_G12D SETD2 154 225 Sex:overall -0.08 -1.07 0.91 1155.03 1.00 3361 145 216 9 FALSE 0.06
uterine cancer KRAS_G12D SETD2 55 89 Sex:overall -0.14 -4.29 4.14 1439.24 1.00 993 51 85 4 FALSE 0.03
colorectal cancer KRAS_G12D PBRM1 145 38 Female -0.20 -1.18 0.53 698.28 1.00 874 142 35 3 TRUE 0.19
colorectal cancer KRAS_G12D PBRM1 160 56 Male 0.08 -0.64 0.76 296.20 1.01 1037 150 46 10 TRUE 0.09
non-small cell lung cancer KRAS_G12D PBRM1 104 57 Female 0.11 -1.03 1.08 1476.43 1.00 1998 100 53 4 TRUE 0.07
non-small cell lung cancer KRAS_G12D PBRM1 48 57 Male -0.22 -1.75 0.95 1334.67 1.00 1453 47 56 1 TRUE 0.13
colorectal cancer KRAS_G12D PBRM1 305 94 Sex:overall -0.07 -0.97 0.85 863.45 1.01 1911 292 81 13 TRUE 0.05
non-small cell lung cancer KRAS_G12D PBRM1 152 114 Sex:overall -0.06 -1.62 1.31 1554.68 1.00 3451 147 109 5 TRUE 0.03
colorectal cancer KRAS_G12D EPHA3 144 52 Female -0.85 -1.86 -0.05 432.88 1.00 861 142 50 2 FALSE 1.13
colorectal cancer KRAS_G12D EPHA3 158 61 Male -0.67 -1.49 0.03 555.15 1.00 1027 152 55 6 FALSE 1.01
non-small cell lung cancer KRAS_G12D EPHA3 104 146 Female -0.59 -1.51 0.22 1624.56 1.00 1914 99 141 5 FALSE 0.71
non-small cell lung cancer KRAS_G12D EPHA3 48 96 Male -0.83 -2.21 0.22 1515.95 1.00 1416 47 95 1 FALSE 0.74
uterine cancer KRAS_G12D EPHA3 53 78 Female 0.29 -0.72 1.20 781.21 1.01 1008 48 73 5 FALSE 0.26
colorectal cancer KRAS_G12D EPHA3 302 113 Sex:overall -0.76 -1.67 0.01 581.62 1.00 1888 294 105 8 FALSE 1.02
non-small cell lung cancer KRAS_G12D EPHA3 152 242 Sex:overall -0.70 -1.92 0.44 1630.44 1.00 3330 146 236 6 FALSE 0.59
uterine cancer KRAS_G12D EPHA3 53 78 Sex:overall 0.24 -4.31 4.58 1513.92 1.00 1008 48 73 5 FALSE 0.04
colorectal cancer KRAS_G12D KIT 160 23 Female -0.92 -2.33 0.14 684.06 1.00 971 159 22 1 TRUE 0.86
colorectal cancer KRAS_G12D KIT 183 31 Male -0.80 -2.03 0.20 512.14 1.01 1156 180 28 3 TRUE 0.78
non-small cell lung cancer KRAS_G12D KIT 107 38 Female -5.19 -12.10 -0.76 534.59 1.00 2068 107 38 0 TRUE 1.12
non-small cell lung cancer KRAS_G12D KIT 50 43 Male -5.16 -11.88 -0.68 509.43 1.00 1518 50 43 0 TRUE 1.14
colorectal cancer KRAS_G12D KIT 343 54 Sex:overall -0.86 -2.21 0.20 652.55 1.00 2127 339 50 4 TRUE 0.77
non-small cell lung cancer KRAS_G12D KIT 157 81 Sex:overall -5.08 -11.69 -0.61 488.51 1.00 3586 157 81 0 TRUE 1.12
colorectal cancer KRAS_G12D KDR 160 26 Female -0.83 -2.20 0.10 31.85 1.10 970 159 25 1 TRUE 0.70
colorectal cancer KRAS_G12D KDR 184 49 Male -0.57 -1.59 0.22 31.68 1.11 1144 179 44 5 TRUE 0.60
non-small cell lung cancer KRAS_G12D KDR 108 94 Female -0.35 -1.56 0.64 975.50 1.00 2022 104 90 4 TRUE 0.29
non-small cell lung cancer KRAS_G12D KDR 50 60 Male -0.51 -2.00 0.70 1200.94 1.00 1500 49 59 1 TRUE 0.34
colorectal cancer KRAS_G12D KDR 344 75 Sex:overall -0.70 -1.90 0.21 40.65 1.09 2114 338 69 6 TRUE 0.61
non-small cell lung cancer KRAS_G12D KDR 158 154 Sex:overall -0.41 -1.84 0.82 1061.56 1.00 3522 153 149 5 TRUE 0.26
colorectal cancer KRAS_G12D RICTOR 144 26 Female -1.76 -4.70 -0.41 1042.98 1.00 883 144 26 0 FALSE 0.91
colorectal cancer KRAS_G12D RICTOR 159 44 Male -1.25 -2.79 -0.10 1015.96 1.00 1042 156 41 3 FALSE 1.23
non-small cell lung cancer KRAS_G12D RICTOR 104 39 Female -1.47 -4.38 0.43 1254.01 1.00 2006 103 38 1 FALSE 0.66
non-small cell lung cancer KRAS_G12D RICTOR 48 25 Male -1.70 -5.03 0.41 1174.15 1.00 1479 48 25 0 FALSE 0.67
uterine cancer KRAS_G12D RICTOR 53 56 Female -0.02 -1.43 1.08 1290.98 1.00 1016 50 53 3 FALSE 0.01
colorectal cancer KRAS_G12D RICTOR 303 70 Sex:overall -1.48 -3.45 -0.14 1087.86 1.00 1925 300 67 3 FALSE 1.07
non-small cell lung cancer KRAS_G12D RICTOR 152 64 Sex:overall -1.59 -4.68 0.46 1172.33 1.00 3485 151 63 1 FALSE 0.65
uterine cancer KRAS_G12D RICTOR 53 56 Sex:overall 0.05 -4.18 4.29 1563.06 1.00 1016 50 53 3 FALSE 0.01
colorectal cancer KRAS_G12D RAD50 144 21 Female -0.39 -2.12 0.55 100.06 1.02 891 141 18 3 FALSE 0.30
colorectal cancer KRAS_G12D RAD50 158 39 Male -0.50 -2.10 0.38 76.17 1.03 1044 155 36 3 FALSE 0.44
colorectal cancer KRAS_G12D RAD50 302 60 Sex:overall -0.45 -2.14 0.63 133.66 1.01 1935 296 54 6 FALSE 0.33
colorectal cancer KRAS_G12D CSF1R 160 21 Female -0.93 -2.39 0.14 978.46 1.00 973 159 20 1 TRUE 0.83
colorectal cancer KRAS_G12D CSF1R 183 35 Male -0.82 -2.09 0.18 945.41 1.00 1155 180 32 3 TRUE 0.85
non-small cell lung cancer KRAS_G12D CSF1R 107 36 Female -1.49 -4.15 0.43 1277.12 1.00 2074 106 35 1 TRUE 0.67
non-small cell lung cancer KRAS_G12D CSF1R 50 33 Male -1.75 -4.89 0.44 1382.35 1.00 1525 50 33 0 TRUE 0.65
colorectal cancer KRAS_G12D CSF1R 343 56 Sex:overall -0.86 -2.22 0.28 941.78 1.00 2128 339 52 4 TRUE 0.78
non-small cell lung cancer KRAS_G12D CSF1R 157 69 Sex:overall -1.60 -4.48 0.53 1265.60 1.00 3599 156 68 1 TRUE 0.66
non-small cell lung cancer KRAS_G12D PARK2 104 39 Female -0.63 -2.74 0.76 796.19 1.00 2005 103 38 1 FALSE 0.32
non-small cell lung cancer KRAS_G12D PARK2 48 26 Male -0.46 -2.51 1.04 966.59 1.00 1477 47 25 1 FALSE 0.21
non-small cell lung cancer KRAS_G12D PARK2 152 65 Sex:overall -0.52 -2.67 1.13 961.76 1.00 3482 150 63 2 FALSE 0.23
non-small cell lung cancer KRAS_G12D NTRK2 104 36 Female -1.48 -4.41 0.44 1340.41 1.00 2011 103 35 1 FALSE 0.66
non-small cell lung cancer KRAS_G12D NTRK2 48 31 Male -1.74 -5.12 0.35 1375.01 1.00 1473 48 31 0 FALSE 0.64
non-small cell lung cancer KRAS_G12D NTRK2 152 67 Sex:overall -1.60 -4.61 0.52 1284.05 1.00 3484 151 66 1 FALSE 0.65
colorectal cancer KRAS_G12D PTCH1 144 67 Female -0.80 -1.71 -0.15 1183.00 1.00 854 141 64 3 TRUE 1.34
colorectal cancer KRAS_G12D PTCH1 158 78 Male -0.60 -1.34 0.14 1415.30 1.00 1027 150 70 8 TRUE 0.97
non-small cell lung cancer KRAS_G12D PTCH1 104 39 Female -0.63 -2.58 0.73 1375.02 1.00 2006 103 38 1 TRUE 0.34
non-small cell lung cancer KRAS_G12D PTCH1 48 23 Male -0.43 -2.49 1.15 1526.50 1.00 1480 47 22 1 TRUE 0.19
uterine cancer KRAS_G12D PTCH1 53 69 Female -0.21 -1.56 0.87 1399.34 1.00 1004 50 66 3 TRUE 0.13
colorectal cancer KRAS_G12D PTCH1 302 145 Sex:overall -0.70 -1.59 0.07 1391.99 1.00 1881 291 134 11 TRUE 0.96
non-small cell lung cancer KRAS_G12D PTCH1 152 62 Sex:overall -0.53 -2.71 1.13 1468.58 1.00 3486 150 60 2 TRUE 0.24
uterine cancer KRAS_G12D PTCH1 53 69 Sex:overall -0.22 -4.52 4.05 1503.55 1.00 1004 50 66 3 TRUE 0.04
colorectal cancer KRAS_G12D TET1 139 40 Female -1.04 -2.68 -0.11 862.14 1.01 843 138 39 1 FALSE 1.06
colorectal cancer KRAS_G12D TET1 152 63 Male -0.68 -1.56 0.11 1319.60 1.00 1014 146 57 6 FALSE 0.96
non-small cell lung cancer KRAS_G12D TET1 104 63 Female -2.04 -4.98 -0.20 1260.66 1.00 1973 103 62 1 FALSE 1.01
non-small cell lung cancer KRAS_G12D TET1 47 63 Male -2.36 -6.18 -0.24 1186.92 1.00 1443 47 63 0 FALSE 0.96
colorectal cancer KRAS_G12D TET1 291 103 Sex:overall -0.86 -1.97 0.07 1464.34 1.00 1857 284 96 7 FALSE 0.94
non-small cell lung cancer KRAS_G12D TET1 151 126 Sex:overall -2.18 -5.36 -0.12 1211.24 1.00 3416 150 125 1 FALSE 0.96
colorectal cancer KRAS_G12D FGFR2 160 21 Female -1.62 -3.42 -0.27 1038.51 1.00 974 159 20 1 TRUE 1.34
colorectal cancer KRAS_G12D FGFR2 183 32 Male -1.64 -3.47 -0.31 1297.66 1.00 1152 182 31 1 TRUE 1.36
uterine cancer KRAS_G12D FGFR2 55 103 Female -1.16 -3.08 0.14 1501.59 1.00 1078 53 101 2 TRUE 0.80
colorectal cancer KRAS_G12D FGFR2 343 53 Sex:overall -1.62 -3.50 -0.22 1238.14 1.00 2126 341 51 2 TRUE 1.29
uterine cancer KRAS_G12D FGFR2 55 103 Sex:overall -1.00 -5.21 3.60 1378.75 1.00 1078 53 101 2 TRUE 0.20
colorectal cancer KRAS_G12D TBX3 144 37 Female -0.25 -1.19 0.38 132.11 1.03 878 141 34 3 FALSE 0.25
colorectal cancer KRAS_G12D TBX3 158 43 Male -0.14 -0.95 0.52 183.00 1.02 1046 152 37 6 FALSE 0.15
non-small cell lung cancer KRAS_G12D TBX3 104 76 Female -2.45 -5.61 -0.45 1404.41 1.00 1970 104 76 0 FALSE 1.22
non-small cell lung cancer KRAS_G12D TBX3 48 61 Male -2.00 -4.87 0.02 1292.30 1.00 1448 47 60 1 FALSE 1.02
uterine cancer KRAS_G12D TBX3 53 54 Female -0.50 -2.36 0.80 847.37 1.00 1013 51 52 2 FALSE 0.26
colorectal cancer KRAS_G12D TBX3 302 80 Sex:overall -0.20 -1.19 0.49 203.26 1.02 1924 293 71 9 FALSE 0.18
non-small cell lung cancer KRAS_G12D TBX3 152 137 Sex:overall -2.19 -5.19 -0.15 1429.15 1.00 3418 151 136 1 FALSE 1.10
uterine cancer KRAS_G12D TBX3 53 54 Sex:overall -0.42 -4.75 4.01 1622.64 1.00 1013 51 52 2 FALSE 0.07
colorectal cancer KRAS_G12D HNF1A 160 27 Female -0.02 -1.26 0.68 25.71 1.07 967 158 25 2 TRUE 0.01
colorectal cancer KRAS_G12D HNF1A 183 25 Male 0.26 -0.52 1.11 847.56 1.01 1163 177 19 6 TRUE 0.29
colorectal cancer KRAS_G12D HNF1A 343 52 Sex:overall 0.14 -0.86 1.00 311.71 1.02 2130 335 44 8 TRUE 0.11
colorectal cancer KRAS_G12D DICER1 144 29 Female -0.86 -2.27 0.13 1134.63 1.00 880 143 28 1 TRUE 0.79
colorectal cancer KRAS_G12D DICER1 158 47 Male -0.58 -1.56 0.33 1318.52 1.00 1046 153 42 5 TRUE 0.65
non-small cell lung cancer KRAS_G12D DICER1 104 52 Female -1.75 -4.78 0.09 1155.28 1.00 1997 103 51 1 TRUE 0.87
non-small cell lung cancer KRAS_G12D DICER1 48 38 Male -1.98 -5.26 0.12 1479.26 1.00 1465 48 38 0 TRUE 0.83
uterine cancer KRAS_G12D DICER1 54 81 Female -0.94 -2.70 0.36 1001.85 1.00 1001 52 79 2 TRUE 0.63
colorectal cancer KRAS_G12D DICER1 302 76 Sex:overall -0.71 -1.94 0.26 1315.03 1.00 1926 296 70 6 TRUE 0.67
non-small cell lung cancer KRAS_G12D DICER1 152 90 Sex:overall -1.84 -4.97 0.10 1342.72 1.00 3462 151 89 1 TRUE 0.85
uterine cancer KRAS_G12D DICER1 54 81 Sex:overall -0.77 -5.49 3.72 1341.19 1.00 1001 52 79 2 TRUE 0.15
colorectal cancer KRAS_G12D SMAD3 147 46 Female 0.20 -0.41 0.82 303.09 1.00 873 138 37 9 TRUE 0.26
colorectal cancer KRAS_G12D SMAD3 161 61 Male 0.12 -0.50 0.70 335.89 1.00 1027 153 53 8 TRUE 0.15
colorectal cancer KRAS_G12D SMAD3 308 107 Sex:overall 0.16 -0.58 0.81 366.67 1.00 1900 291 90 17 TRUE 0.18
colorectal cancer KRAS_G12D NTRK3 144 24 Female -1.56 -5.37 -0.07 1051.00 1.00 885 144 24 0 FALSE 0.59
colorectal cancer KRAS_G12D NTRK3 158 46 Male -0.58 -1.75 0.37 1328.22 1.00 1040 153 41 5 FALSE 0.57
non-small cell lung cancer KRAS_G12D NTRK3 104 106 Female -1.25 -2.72 -0.14 1405.27 1.00 1951 102 104 2 FALSE 1.22
non-small cell lung cancer KRAS_G12D NTRK3 48 101 Male -1.30 -3.08 -0.04 1362.64 1.00 1416 47 100 1 FALSE 1.06
colorectal cancer KRAS_G12D NTRK3 302 70 Sex:overall -1.03 -3.40 0.41 1232.96 1.00 1925 297 65 5 FALSE 0.51
non-small cell lung cancer KRAS_G12D NTRK3 152 207 Sex:overall -1.28 -3.01 0.08 1436.72 1.00 3367 149 204 3 FALSE 0.93
colorectal cancer KRAS_G12D AXIN1 144 33 Female -0.02 -0.97 0.70 549.21 1.00 880 141 30 3 FALSE 0.02
colorectal cancer KRAS_G12D AXIN1 160 38 Male 0.11 -0.66 0.86 657.01 1.00 1048 153 31 7 FALSE 0.12
colorectal cancer KRAS_G12D AXIN1 304 71 Sex:overall 0.04 -0.90 0.84 790.56 1.00 1928 294 61 10 FALSE 0.03
colorectal cancer KRAS_G12D GRIN2A 144 62 Female -0.36 -1.12 0.40 434.91 1.01 857 135 53 9 FALSE 0.44
colorectal cancer KRAS_G12D GRIN2A 158 74 Male -0.73 -1.76 -0.01 754.09 1.00 1015 155 71 3 FALSE 0.96
non-small cell lung cancer KRAS_G12D GRIN2A 105 102 Female 0.12 -0.74 0.88 1313.01 1.00 1954 98 95 7 FALSE 0.11
non-small cell lung cancer KRAS_G12D GRIN2A 48 91 Male -0.49 -2.23 0.62 1302.86 1.00 1417 47 90 1 FALSE 0.31
uterine cancer KRAS_G12D GRIN2A 53 77 Female -1.85 -5.00 -0.08 922.53 1.00 1002 52 76 1 FALSE 0.84
colorectal cancer KRAS_G12D GRIN2A 302 136 Sex:overall -0.53 -1.56 0.36 954.59 1.00 1872 290 124 12 FALSE 0.57
non-small cell lung cancer KRAS_G12D GRIN2A 153 193 Sex:overall -0.19 -1.74 1.03 1274.66 1.00 3371 145 185 8 FALSE 0.11
uterine cancer KRAS_G12D GRIN2A 53 77 Sex:overall -1.52 -6.30 3.63 1185.36 1.00 1002 52 76 1 FALSE 0.29
colorectal cancer KRAS_G12D PALB2 144 20 Female -1.99 -4.58 -0.39 957.49 1.00 888 144 20 0 TRUE 1.15
colorectal cancer KRAS_G12D PALB2 158 36 Male -1.65 -3.69 -0.27 606.61 1.00 1044 156 34 2 TRUE 1.33
non-small cell lung cancer KRAS_G12D PALB2 104 31 Female -0.50 -2.37 0.93 944.92 1.00 2015 103 30 1 TRUE 0.25
non-small cell lung cancer KRAS_G12D PALB2 48 29 Male -0.40 -2.24 1.05 925.34 1.00 1475 47 28 1 TRUE 0.18
colorectal cancer KRAS_G12D PALB2 302 56 Sex:overall -1.79 -3.93 -0.18 771.12 1.00 1932 300 54 2 TRUE 1.20
non-small cell lung cancer KRAS_G12D PALB2 152 60 Sex:overall -0.45 -2.42 1.13 1018.39 1.00 3490 150 58 2 TRUE 0.20
colorectal cancer KRAS_G12D CTCF 145 40 Female 0.32 -0.41 0.85 61.52 1.04 878 139 34 6 FALSE 0.49
colorectal cancer KRAS_G12D CTCF 158 50 Male 0.36 -0.28 0.88 88.15 1.02 1041 149 41 9 FALSE 0.63
uterine cancer KRAS_G12D CTCF 54 168 Female 0.24 -0.49 0.89 1421.24 1.00 916 44 158 10 FALSE 0.29
colorectal cancer KRAS_G12D CTCF 303 90 Sex:overall 0.34 -0.38 0.88 98.47 1.02 1919 288 75 15 FALSE 0.48
uterine cancer KRAS_G12D CTCF 54 168 Sex:overall 0.18 -4.26 4.43 1345.28 1.00 916 44 158 10 FALSE 0.03
colorectal cancer KRAS_G12D CDH1 160 21 Female -1.19 -4.56 0.24 649.94 1.00 977 160 21 0 TRUE 0.46
colorectal cancer KRAS_G12D CDH1 184 33 Male -0.32 -1.52 0.65 396.88 1.00 1154 179 28 5 TRUE 0.26
colorectal cancer KRAS_G12D CDH1 344 54 Sex:overall -0.75 -3.07 0.62 841.43 1.00 2131 339 49 5 TRUE 0.38
colorectal cancer KRAS_G12D CDK12 144 42 Female -0.44 -1.32 0.33 1173.81 1.00 874 141 39 3 FALSE 0.54
colorectal cancer KRAS_G12D CDK12 159 48 Male -0.33 -1.12 0.40 1040.40 1.00 1040 153 42 6 FALSE 0.41
non-small cell lung cancer KRAS_G12D CDK12 104 31 Female -1.12 -3.73 0.78 73.94 1.05 2014 103 30 1 FALSE 0.43
non-small cell lung cancer KRAS_G12D CDK12 48 28 Male -1.37 -4.92 0.70 95.09 1.05 1475 48 28 0 FALSE 0.46
colorectal cancer KRAS_G12D CDK12 303 90 Sex:overall -0.38 -1.25 0.43 1167.67 1.00 1914 294 81 9 FALSE 0.39
non-small cell lung cancer KRAS_G12D CDK12 152 59 Sex:overall -1.22 -4.34 0.88 80.10 1.05 3489 151 58 1 FALSE 0.44
cancer of unknown primary KRAS_G12D STK11 35 28 Female -4.65 -12.32 -0.92 33.90 1.07 367 35 28 0 TRUE 0.87
cancer of unknown primary KRAS_G12D STK11 19 24 Male -4.62 -12.36 -0.93 38.33 1.07 348 19 24 0 TRUE 0.85
non-small cell lung cancer KRAS_G12D STK11 108 295 Female 0.60 0.11 1.08 1043.70 1.00 1847 83 270 25 TRUE 1.81
non-small cell lung cancer KRAS_G12D STK11 50 248 Male -0.04 -0.96 0.63 1443.08 1.00 1323 44 242 6 TRUE 0.04
cancer of unknown primary KRAS_G12D STK11 54 52 Sex:overall -4.58 -12.28 -0.91 35.35 1.07 715 54 52 0 TRUE 0.86
non-small cell lung cancer KRAS_G12D STK11 158 543 Sex:overall 0.31 -0.80 1.39 1510.74 1.00 3170 127 512 31 TRUE 0.25
colorectal cancer KRAS_G12D DNMT1 139 39 Female -0.59 -1.56 0.18 285.50 1.02 843 137 37 2 FALSE 0.72
colorectal cancer KRAS_G12D DNMT1 154 51 Male -0.43 -1.26 0.27 207.27 1.02 1011 148 45 6 FALSE 0.56
colorectal cancer KRAS_G12D DNMT1 293 90 Sex:overall -0.51 -1.42 0.26 282.20 1.02 1854 285 82 8 FALSE 0.59
colorectal cancer KRAS_G12D BRD4 144 31 Female -0.48 -1.75 0.33 1294.74 1.00 878 142 29 2 FALSE 0.43
colorectal cancer KRAS_G12D BRD4 160 57 Male -0.11 -0.94 0.58 1494.37 1.00 1031 152 49 8 FALSE 0.11
non-small cell lung cancer KRAS_G12D BRD4 104 27 Female -4.73 -11.08 -0.55 281.71 1.00 2018 104 27 0 FALSE 1.01
non-small cell lung cancer KRAS_G12D BRD4 48 26 Male -4.68 -11.36 -0.30 267.28 1.00 1476 48 26 0 FALSE 0.97
uterine cancer KRAS_G12D BRD4 54 70 Female 0.08 -1.20 1.09 1023.41 1.00 1001 50 66 4 FALSE 0.05
colorectal cancer KRAS_G12D BRD4 304 88 Sex:overall -0.29 -1.46 0.64 1464.14 1.00 1909 294 78 10 FALSE 0.21
non-small cell lung cancer KRAS_G12D BRD4 152 53 Sex:overall -4.63 -10.94 -0.38 267.53 1.00 3494 152 53 0 FALSE 0.97
uterine cancer KRAS_G12D BRD4 54 70 Sex:overall 0.12 -4.08 4.38 1499.40 1.00 1001 50 66 4 FALSE 0.02
colorectal cancer KRAS_G12D ASXL1 144 49 Female -1.25 -2.60 -0.35 1154.83 1.00 865 143 48 1 TRUE 1.58
colorectal cancer KRAS_G12D ASXL1 158 60 Male -0.98 -1.94 -0.11 1084.83 1.00 1024 153 55 5 TRUE 1.47
non-small cell lung cancer KRAS_G12D ASXL1 104 40 Female -0.66 -2.47 0.69 875.25 1.00 2006 102 38 2 TRUE 0.36
non-small cell lung cancer KRAS_G12D ASXL1 48 46 Male -1.43 -4.76 0.42 820.84 1.00 1469 48 46 0 TRUE 0.46
uterine cancer KRAS_G12D ASXL1 55 60 Female 0.25 -0.91 1.28 1002.84 1.00 1012 51 56 4 TRUE 0.19
colorectal cancer KRAS_G12D ASXL1 302 109 Sex:overall -1.12 -2.29 -0.23 1203.87 1.00 1889 296 103 6 TRUE 1.39
non-small cell lung cancer KRAS_G12D ASXL1 152 86 Sex:overall -0.98 -3.36 0.85 669.78 1.00 3475 150 84 2 TRUE 0.44
uterine cancer KRAS_G12D ASXL1 55 60 Sex:overall 0.13 -4.05 3.91 1477.35 1.00 1012 51 56 4 TRUE 0.02
colorectal cancer KRAS_G12D EP300 144 53 Female -0.86 -1.86 -0.06 1202.79 1.00 868 142 51 2 TRUE 1.22
colorectal cancer KRAS_G12D EP300 159 72 Male -0.65 -1.42 0.06 1137.98 1.01 1021 152 65 7 TRUE 1.08
non-small cell lung cancer KRAS_G12D EP300 104 54 Female -0.57 -2.12 0.56 1423.79 1.00 1998 102 52 2 TRUE 0.39
non-small cell lung cancer KRAS_G12D EP300 48 54 Male -0.63 -2.33 0.64 1393.29 1.00 1453 47 53 1 TRUE 0.40
uterine cancer KRAS_G12D EP300 54 103 Female -0.33 -1.40 0.60 1216.79 1.00 982 50 99 4 TRUE 0.27
colorectal cancer KRAS_G12D EP300 303 125 Sex:overall -0.77 -1.82 0.10 1263.15 1.00 1889 294 116 9 TRUE 0.84
non-small cell lung cancer KRAS_G12D EP300 152 108 Sex:overall -0.59 -2.29 0.74 1385.43 1.00 3451 149 105 3 TRUE 0.34
uterine cancer KRAS_G12D EP300 54 103 Sex:overall -0.30 -4.70 3.72 1489.35 1.00 982 50 99 4 TRUE 0.06
colorectal cancer KRAS_G12D ERBB4 160 60 Female -0.18 -0.82 0.35 457.51 1.00 944 154 54 6 TRUE 0.25
colorectal cancer KRAS_G12D ERBB4 183 78 Male -0.10 -0.65 0.43 618.90 1.00 1127 172 67 11 TRUE 0.13
non-small cell lung cancer KRAS_G12D ERBB4 107 108 Female 0.02 -0.87 0.78 1207.60 1.00 2018 101 102 6 TRUE 0.02
non-small cell lung cancer KRAS_G12D ERBB4 50 85 Male -0.14 -1.27 0.73 1382.98 1.00 1490 48 83 2 TRUE 0.11
colorectal cancer KRAS_G12D ERBB4 343 138 Sex:overall -0.14 -0.82 0.46 780.75 1.00 2071 326 121 17 TRUE 0.17
non-small cell lung cancer KRAS_G12D ERBB4 157 193 Sex:overall -0.03 -1.10 0.99 1515.16 1.00 3508 149 185 8 TRUE 0.02
colorectal cancer KRAS_G12D MDC1 139 27 Female -0.65 -1.78 0.31 1200.27 1.00 854 136 24 3 FALSE 0.65
colorectal cancer KRAS_G12D MDC1 152 38 Male -0.76 -1.96 0.18 1433.90 1.00 1022 150 36 2 FALSE 0.78
non-small cell lung cancer KRAS_G12D MDC1 104 52 Female -1.00 -2.81 0.28 1485.65 1.00 1986 103 51 1 FALSE 0.64
non-small cell lung cancer KRAS_G12D MDC1 47 43 Male -0.87 -2.94 0.67 1240.34 1.00 1461 46 42 1 FALSE 0.49
colorectal cancer KRAS_G12D MDC1 291 65 Sex:overall -0.70 -1.92 0.35 1357.32 1.00 1876 286 60 5 FALSE 0.61
non-small cell lung cancer KRAS_G12D MDC1 151 95 Sex:overall -0.93 -3.01 0.55 1421.75 1.00 3447 149 93 2 FALSE 0.53
colorectal cancer KRAS_G12D RECQL4 139 30 Female 0.40 -0.32 1.06 1017.55 1.00 857 132 23 7 TRUE 0.56
colorectal cancer KRAS_G12D RECQL4 152 51 Male 0.25 -0.50 0.88 1279.08 1.00 1014 145 44 7 TRUE 0.33
non-small cell lung cancer KRAS_G12D RECQL4 104 36 Female -5.01 -11.79 -0.81 727.58 1.00 1998 104 36 0 TRUE 1.07
non-small cell lung cancer KRAS_G12D RECQL4 47 28 Male -4.97 -11.61 -0.62 734.83 1.00 1470 47 28 0 TRUE 1.05
colorectal cancer KRAS_G12D RECQL4 291 81 Sex:overall 0.32 -0.65 1.22 1390.58 1.00 1871 277 67 14 TRUE 0.29
non-small cell lung cancer KRAS_G12D RECQL4 151 64 Sex:overall -4.91 -11.34 -0.75 732.56 1.00 3468 151 64 0 TRUE 1.07
colorectal cancer KRAS_G12D MED12 145 54 Female -0.57 -1.32 0.12 1443.89 1.00 864 140 49 5 TRUE 0.88
colorectal cancer KRAS_G12D MED12 158 54 Male -0.60 -1.34 0.12 1289.72 1.00 1033 154 50 4 TRUE 0.93
non-small cell lung cancer KRAS_G12D MED12 104 137 Female -0.78 -2.00 0.16 1506.91 1.00 1922 100 133 4 TRUE 0.79
non-small cell lung cancer KRAS_G12D MED12 48 39 Male -1.65 -5.36 0.30 1289.85 1.00 1465 48 39 0 TRUE 0.58
uterine cancer KRAS_G12D MED12 53 140 Female -1.53 -3.31 -0.18 1415.96 1.00 950 51 138 2 TRUE 1.22
colorectal cancer KRAS_G12D MED12 303 108 Sex:overall -0.58 -1.35 0.21 1510.17 1.00 1897 294 99 9 TRUE 0.77
non-small cell lung cancer KRAS_G12D MED12 152 176 Sex:overall -1.18 -3.65 0.62 1411.42 1.00 3387 148 172 4 TRUE 0.53
uterine cancer KRAS_G12D MED12 53 140 Sex:overall -1.28 -5.53 3.40 1530.49 1.00 950 51 138 2 TRUE 0.27
colorectal cancer KRAS_G12D ERCC5 139 31 Female -0.78 -1.96 0.24 1401.99 1.00 855 136 28 3 TRUE 0.78
colorectal cancer KRAS_G12D ERCC5 152 27 Male -0.94 -2.38 0.12 1461.02 1.00 1023 151 26 1 TRUE 0.82
non-small cell lung cancer KRAS_G12D ERCC5 104 39 Female -0.76 -2.73 0.66 1095.35 1.00 1994 103 38 1 TRUE 0.42
non-small cell lung cancer KRAS_G12D ERCC5 47 34 Male -0.62 -2.67 0.91 1119.63 1.00 1470 46 33 1 TRUE 0.31
uterine cancer KRAS_G12D ERCC5 51 52 Female 0.94 -0.05 1.83 1349.98 1.00 967 45 46 6 TRUE 1.30
colorectal cancer KRAS_G12D ERCC5 291 58 Sex:overall -0.84 -2.17 0.26 1447.30 1.00 1878 287 54 4 TRUE 0.74
non-small cell lung cancer KRAS_G12D ERCC5 151 73 Sex:overall -0.68 -2.80 0.99 1053.73 1.00 3464 149 71 2 TRUE 0.33
uterine cancer KRAS_G12D ERCC5 51 52 Sex:overall 0.81 -3.80 5.04 1450.38 1.00 967 45 46 6 TRUE 0.16
colorectal cancer KRAS_G12D PIK3CD 140 34 Female -0.56 -1.50 0.29 1106.26 1.00 848 137 31 3 FALSE 0.67
colorectal cancer KRAS_G12D PIK3CD 152 35 Male -0.56 -1.51 0.34 1171.63 1.00 1021 149 32 3 FALSE 0.64
colorectal cancer KRAS_G12D PIK3CD 292 69 Sex:overall -0.56 -1.56 0.38 1157.57 1.01 1869 286 63 6 FALSE 0.59
colorectal cancer KRAS_G12D BRCA1 144 28 Female -0.46 -1.49 0.41 1008.86 1.00 883 142 26 2 TRUE 0.45
colorectal cancer KRAS_G12D BRCA1 158 51 Male -0.28 -1.07 0.47 760.78 1.00 1042 152 45 6 TRUE 0.32
non-small cell lung cancer KRAS_G12D BRCA1 104 50 Female -0.08 -1.39 0.94 1356.80 1.00 1999 101 47 3 TRUE 0.05
non-small cell lung cancer KRAS_G12D BRCA1 48 47 Male -0.26 -1.87 0.90 1201.61 1.00 1458 47 46 1 TRUE 0.16
colorectal cancer KRAS_G12D BRCA1 302 79 Sex:overall -0.36 -1.41 0.62 1022.19 1.00 1925 294 71 8 TRUE 0.30
non-small cell lung cancer KRAS_G12D BRCA1 152 97 Sex:overall -0.18 -1.66 1.11 1255.61 1.00 3457 148 93 4 TRUE 0.09
colorectal cancer KRAS_G12D RBM10 144 41 Female -0.29 -1.43 0.60 764.72 1.00 875 141 38 3 FALSE 0.24
colorectal cancer KRAS_G12D RBM10 158 31 Male 0.29 -0.54 1.17 1347.20 1.00 1051 151 24 7 FALSE 0.29
non-small cell lung cancer KRAS_G12D RBM10 108 239 Female 0.82 0.35 1.26 1433.43 1.00 1841 84 215 24 FALSE 3.46
non-small cell lung cancer KRAS_G12D RBM10 48 144 Male 0.51 -0.26 1.12 1428.87 1.00 1367 42 138 6 FALSE 0.84
uterine cancer KRAS_G12D RBM10 53 54 Female 0.03 -1.35 1.11 925.11 1.00 1015 50 51 3 FALSE 0.02
colorectal cancer KRAS_G12D RBM10 302 72 Sex:overall -0.01 -1.34 1.11 1141.83 1.00 1926 292 62 10 FALSE 0.01
non-small cell lung cancer KRAS_G12D RBM10 156 383 Sex:overall 0.67 -0.22 1.44 1395.77 1.00 3208 126 353 30 FALSE 0.89
uterine cancer KRAS_G12D RBM10 53 54 Sex:overall 0.06 -4.33 4.13 1463.95 1.00 1015 50 51 3 FALSE 0.01
colorectal cancer KRAS_G12D TSC1 144 27 Female -0.08 -1.04 0.64 1092.18 1.00 885 141 24 3 TRUE 0.07
colorectal cancer KRAS_G12D TSC1 158 40 Male 0.01 -0.76 0.73 1139.26 1.00 1050 152 34 6 TRUE 0.01
non-small cell lung cancer KRAS_G12D TSC1 104 30 Female -4.91 -11.81 -0.74 420.16 1.00 2014 104 30 0 TRUE 1.02
non-small cell lung cancer KRAS_G12D TSC1 48 27 Male -4.89 -11.70 -0.62 508.10 1.00 1475 48 27 0 TRUE 1.00
uterine cancer KRAS_G12D TSC1 55 62 Female 0.95 0.04 1.75 1467.20 1.00 1014 48 55 7 TRUE 1.51
colorectal cancer KRAS_G12D TSC1 302 67 Sex:overall -0.04 -0.98 0.78 992.48 1.00 1935 293 58 9 TRUE 0.03
non-small cell lung cancer KRAS_G12D TSC1 152 57 Sex:overall -4.81 -11.28 -0.62 478.71 1.00 3489 152 57 0 TRUE 1.01
uterine cancer KRAS_G12D TSC1 55 62 Sex:overall 0.92 -3.57 5.16 1482.77 1.00 1014 48 55 7 TRUE 0.18
colorectal cancer KRAS_G12D FLCN 144 30 Female -0.96 -2.44 0.14 1059.48 1.00 879 143 29 1 TRUE 0.82
colorectal cancer KRAS_G12D FLCN 159 24 Male -0.66 -1.98 0.50 1369.36 1.00 1057 156 21 3 TRUE 0.54
colorectal cancer KRAS_G12D FLCN 303 54 Sex:overall -0.82 -2.35 0.42 1112.46 1.00 1936 299 50 4 TRUE 0.61
cancer of unknown primary KRAS_G12D NF1 35 27 Female -1.71 -4.80 0.29 235.57 1.01 363 34 26 1 TRUE 0.76
cancer of unknown primary KRAS_G12D NF1 19 30 Male -2.03 -5.29 0.15 255.46 1.01 342 19 30 0 TRUE 0.81
colorectal cancer KRAS_G12D NF1 144 55 Female -0.79 -1.64 -0.07 1350.45 1.00 865 141 52 3 TRUE 1.31
colorectal cancer KRAS_G12D NF1 159 87 Male -0.60 -1.33 0.05 1152.83 1.00 1020 151 79 8 TRUE 1.05
non-small cell lung cancer KRAS_G12D NF1 104 165 Female -0.66 -1.61 0.17 1427.72 1.00 1907 99 160 5 TRUE 0.83
non-small cell lung cancer KRAS_G12D NF1 48 150 Male -0.84 -1.99 0.08 1514.74 1.00 1375 46 148 2 TRUE 0.92
uterine cancer KRAS_G12D NF1 53 123 Female -0.53 -1.70 0.45 1447.40 1.00 983 49 119 4 TRUE 0.47
cancer of unknown primary KRAS_G12D NF1 54 57 Sex:overall -1.83 -4.89 0.27 241.69 1.01 705 53 56 1 TRUE 0.78
colorectal cancer KRAS_G12D NF1 303 142 Sex:overall -0.68 -1.56 0.14 1328.17 1.00 1885 292 131 11 TRUE 0.88
non-small cell lung cancer KRAS_G12D NF1 152 315 Sex:overall -0.74 -2.00 0.38 1515.33 1.00 3282 145 308 7 TRUE 0.62
uterine cancer KRAS_G12D NF1 53 123 Sex:overall -0.41 -4.54 3.94 1398.64 1.00 983 49 119 4 TRUE 0.08
colorectal cancer KRAS_G12D FLT1 144 30 Female -0.32 -1.47 0.46 1037.33 1.00 883 142 28 2 FALSE 0.28
colorectal cancer KRAS_G12D FLT1 160 52 Male -0.02 -0.74 0.67 1273.98 1.00 1039 152 44 8 FALSE 0.01
non-small cell lung cancer KRAS_G12D FLT1 104 75 Female -1.22 -3.08 0.08 1373.59 1.00 1977 102 73 2 FALSE 0.87
non-small cell lung cancer KRAS_G12D FLT1 48 61 Male -1.66 -4.44 -0.03 1029.85 1.00 1446 48 61 0 FALSE 0.67
uterine cancer KRAS_G12D FLT1 53 56 Female -1.60 -4.56 0.35 137.09 1.01 1014 52 55 1 FALSE 0.67
colorectal cancer KRAS_G12D FLT1 304 82 Sex:overall -0.17 -1.32 0.69 1217.04 1.00 1922 294 72 10 FALSE 0.13
non-small cell lung cancer KRAS_G12D FLT1 152 136 Sex:overall -1.39 -3.42 0.24 1149.93 1.00 3423 150 134 2 FALSE 0.83
uterine cancer KRAS_G12D FLT1 53 56 Sex:overall -1.31 -5.54 3.78 352.65 1.00 1014 52 55 1 FALSE 0.24
colorectal cancer KRAS_G12D RPTOR 145 32 Female -0.40 -1.38 0.42 1106.79 1.00 877 142 29 3 FALSE 0.43
colorectal cancer KRAS_G12D RPTOR 158 38 Male -0.37 -1.27 0.41 1167.92 1.00 1047 154 34 4 FALSE 0.41
non-small cell lung cancer KRAS_G12D RPTOR 104 34 Female -5.11 -11.58 -0.82 647.12 1.00 2010 104 34 0 FALSE 1.18
non-small cell lung cancer KRAS_G12D RPTOR 48 31 Male -5.06 -11.53 -0.73 676.44 1.00 1472 48 31 0 FALSE 1.15
colorectal cancer KRAS_G12D RPTOR 303 70 Sex:overall -0.40 -1.40 0.43 1237.59 1.00 1924 296 63 7 FALSE 0.37
non-small cell lung cancer KRAS_G12D RPTOR 152 65 Sex:overall -5.01 -11.36 -0.70 634.30 1.00 3482 152 65 0 FALSE 1.14
colorectal cancer KRAS_G12D RASA1 144 30 Female -0.56 -1.48 0.29 1099.81 1.00 883 141 27 3 FALSE 0.66
colorectal cancer KRAS_G12D RASA1 158 43 Male -0.61 -1.55 0.26 1039.33 1.00 1048 155 40 3 FALSE 0.73
non-small cell lung cancer KRAS_G12D RASA1 104 47 Female -0.64 -2.27 0.60 1364.43 1.00 1999 103 46 1 FALSE 0.41
non-small cell lung cancer KRAS_G12D RASA1 48 51 Male -0.33 -1.82 0.93 1311.90 1.00 1453 46 49 2 FALSE 0.19
uterine cancer KRAS_G12D RASA1 53 105 Female -6.21 -16.11 -1.42 1393.27 1.00 989 53 105 0 FALSE 0.94
colorectal cancer KRAS_G12D RASA1 302 73 Sex:overall -0.58 -1.58 0.36 1308.79 1.00 1931 296 67 6 FALSE 0.60
non-small cell lung cancer KRAS_G12D RASA1 152 98 Sex:overall -0.46 -2.25 1.00 1178.51 1.00 3452 149 95 3 FALSE 0.24
uterine cancer KRAS_G12D RASA1 53 105 Sex:overall -4.61 -11.85 2.80 1348.40 1.00 989 53 105 0 FALSE 0.72
colorectal cancer KRAS_G12D EPHA5 145 58 Female -0.50 -1.22 0.16 1482.92 1.00 859 140 53 5 FALSE 0.82
colorectal cancer KRAS_G12D EPHA5 158 86 Male -0.46 -1.14 0.14 1512.92 1.00 1016 150 78 8 FALSE 0.84
non-small cell lung cancer KRAS_G12D EPHA5 104 147 Female -0.55 -1.48 0.32 309.52 1.02 1913 98 141 6 FALSE 0.62
non-small cell lung cancer KRAS_G12D EPHA5 48 113 Male -1.55 -4.81 -0.08 1106.79 1.00 1402 48 113 0 FALSE 0.65
uterine cancer KRAS_G12D EPHA5 55 98 Female -0.32 -1.52 0.74 1355.89 1.00 992 51 94 4 FALSE 0.24
colorectal cancer KRAS_G12D EPHA5 303 144 Sex:overall -0.49 -1.29 0.20 1493.62 1.00 1875 290 131 13 FALSE 0.68
non-small cell lung cancer KRAS_G12D EPHA5 152 260 Sex:overall -1.02 -3.22 0.39 1197.69 1.00 3315 146 254 6 FALSE 0.56
uterine cancer KRAS_G12D EPHA5 55 98 Sex:overall -0.26 -4.87 4.25 1551.83 1.00 992 51 94 4 FALSE 0.05
colorectal cancer KRAS_G12D AR 144 59 Female -0.73 -1.53 -0.04 247.34 1.01 859 139 54 5 TRUE 1.15
colorectal cancer KRAS_G12D AR 158 57 Male -0.82 -1.72 -0.11 170.44 1.02 1027 155 54 3 TRUE 1.24
non-small cell lung cancer KRAS_G12D AR 104 81 Female -0.35 -1.57 0.68 1486.13 1.00 1974 101 78 3 TRUE 0.27
non-small cell lung cancer KRAS_G12D AR 48 29 Male -0.28 -1.94 1.14 1481.12 1.00 1474 47 28 1 TRUE 0.14
uterine cancer KRAS_G12D AR 53 65 Female -0.17 -1.59 0.94 1381.07 1.00 1006 50 62 3 TRUE 0.10
colorectal cancer KRAS_G12D AR 302 116 Sex:overall -0.77 -1.69 0.02 304.13 1.02 1886 294 108 8 TRUE 1.02
non-small cell lung cancer KRAS_G12D AR 152 110 Sex:overall -0.33 -2.00 1.24 1297.90 1.00 3448 148 106 4 TRUE 0.16
uterine cancer KRAS_G12D AR 53 65 Sex:overall -0.15 -4.58 4.47 1439.65 1.00 1006 50 62 3 TRUE 0.03
colorectal cancer KRAS_G12D GNAS 160 41 Female 0.13 -0.61 0.81 1224.26 1.00 962 154 35 6 TRUE 0.15
colorectal cancer KRAS_G12D GNAS 183 34 Male 0.17 -0.54 0.82 1125.06 1.00 1152 177 28 6 TRUE 0.20
pancreatic cancer KRAS_G12D GNAS 247 25 Female -0.51 -1.40 0.06 76.04 1.06 488 243 21 4 TRUE 0.71
pancreatic cancer KRAS_G12D GNAS 266 37 Male -0.32 -1.00 0.27 186.41 1.03 545 255 26 11 TRUE 0.51
colorectal cancer KRAS_G12D GNAS 343 75 Sex:overall 0.15 -0.62 0.94 1128.61 1.00 2114 331 63 12 TRUE 0.15
pancreatic cancer KRAS_G12D GNAS 513 62 Sex:overall -0.42 -1.28 0.22 175.17 1.03 1033 498 47 15 TRUE 0.55
colorectal cancer KRAS_G12D ASXL2 144 20 Female -2.04 -5.65 -0.35 1424.08 1.00 887 144 20 0 FALSE 0.94
colorectal cancer KRAS_G12D ASXL2 158 51 Male -1.25 -2.66 -0.14 1602.78 1.00 1047 155 48 3 FALSE 1.32
non-small cell lung cancer KRAS_G12D ASXL2 104 32 Female -1.38 -4.40 0.47 1261.92 1.00 2014 103 31 1 FALSE 0.59
non-small cell lung cancer KRAS_G12D ASXL2 48 31 Male -1.71 -5.22 0.47 1316.03 1.00 1472 48 31 0 FALSE 0.61
colorectal cancer KRAS_G12D ASXL2 302 71 Sex:overall -1.57 -3.83 0.13 1308.38 1.00 1934 299 68 3 FALSE 0.91
non-small cell lung cancer KRAS_G12D ASXL2 152 63 Sex:overall -1.49 -4.63 0.70 1267.60 1.00 3486 151 62 1 FALSE 0.57
colorectal cancer KRAS_G12D SF3B1 144 18 Female -1.15 -2.85 0.22 1377.95 1.00 891 143 17 1 TRUE 0.83
colorectal cancer KRAS_G12D SF3B1 158 52 Male -1.05 -2.29 0.00 1464.29 1.00 1041 155 49 3 TRUE 1.14
non-small cell lung cancer KRAS_G12D SF3B1 104 55 Female -0.98 -2.93 0.40 1338.29 1.00 1993 103 54 1 TRUE 0.62
non-small cell lung cancer KRAS_G12D SF3B1 48 32 Male -0.77 -2.78 0.90 1408.87 1.00 1472 47 31 1 TRUE 0.39
colorectal cancer KRAS_G12D SF3B1 302 70 Sex:overall -1.09 -2.75 0.46 1522.43 1.00 1932 298 66 4 TRUE 0.73
non-small cell lung cancer KRAS_G12D SF3B1 152 87 Sex:overall -0.89 -2.92 0.76 1421.50 1.00 3465 150 85 2 TRUE 0.46
colorectal cancer KRAS_G12D MLH1 160 20 Female -1.33 -5.03 0.19 991.60 1.01 977 160 20 0 TRUE 0.49
colorectal cancer KRAS_G12D MLH1 183 36 Male -0.38 -1.52 0.56 1122.41 1.00 1153 178 31 5 TRUE 0.32
colorectal cancer KRAS_G12D MLH1 343 56 Sex:overall -0.83 -3.19 0.62 1118.42 1.00 2130 338 51 5 TRUE 0.41
colorectal cancer KRAS_G12D ROS1 144 32 Female -0.86 -1.91 0.22 1413.70 1.00 879 141 29 3 TRUE 0.93
colorectal cancer KRAS_G12D ROS1 158 71 Male -1.10 -2.15 -0.21 1500.66 1.00 1028 155 68 3 TRUE 1.57
non-small cell lung cancer KRAS_G12D ROS1 104 57 Female -1.98 -4.51 -0.01 922.13 1.00 1989 103 56 1 TRUE 1.05
non-small cell lung cancer KRAS_G12D ROS1 48 54 Male -2.30 -5.24 -0.08 1220.82 1.00 1451 48 54 0 TRUE 0.92
uterine cancer KRAS_G12D ROS1 54 100 Female -0.62 -2.00 0.45 1594.07 1.00 1009 51 97 3 TRUE 0.48
colorectal cancer KRAS_G12D ROS1 302 103 Sex:overall -0.97 -2.31 0.30 1480.43 1.00 1907 296 97 6 TRUE 0.85
non-small cell lung cancer KRAS_G12D ROS1 152 111 Sex:overall -2.11 -4.96 0.00 1009.67 1.00 3440 151 110 1 TRUE 1.04
uterine cancer KRAS_G12D ROS1 54 100 Sex:overall -0.48 -4.82 4.16 1205.82 1.00 1009 51 97 3 TRUE 0.09
colorectal cancer KRAS_G12D PIK3R2 144 24 Female -0.42 -1.54 0.55 854.26 1.00 888 141 21 3 FALSE 0.38
colorectal cancer KRAS_G12D PIK3R2 158 28 Male -0.52 -1.71 0.40 937.35 1.00 1050 156 26 2 FALSE 0.47
colorectal cancer KRAS_G12D PIK3R2 302 52 Sex:overall -0.48 -1.69 0.52 919.92 1.00 1938 297 47 5 FALSE 0.41
colorectal cancer KRAS_G12D FLT3 160 19 Female -0.71 -2.12 0.28 42.54 1.04 975 159 18 1 TRUE 0.59
colorectal cancer KRAS_G12D FLT3 183 33 Male -0.62 -1.86 0.28 69.94 1.03 1158 180 30 3 TRUE 0.59
non-small cell lung cancer KRAS_G12D FLT3 108 42 Female -0.15 -1.49 1.04 1183.57 1.00 2069 105 39 3 TRUE 0.09
non-small cell lung cancer KRAS_G12D FLT3 50 39 Male -0.83 -3.96 0.75 1251.12 1.00 1521 50 39 0 TRUE 0.31
uterine cancer KRAS_G12D FLT3 55 61 Female -1.47 -4.32 0.45 1178.66 1.00 1128 54 60 1 TRUE 0.67
colorectal cancer KRAS_G12D FLT3 343 52 Sex:overall -0.67 -2.11 0.29 65.85 1.04 2133 339 48 4 TRUE 0.52
non-small cell lung cancer KRAS_G12D FLT3 158 81 Sex:overall -0.47 -2.60 1.05 1278.67 1.00 3590 155 78 3 TRUE 0.21
uterine cancer KRAS_G12D FLT3 55 61 Sex:overall -1.28 -5.55 3.46 1315.46 1.00 1128 54 60 1 TRUE 0.27
colorectal cancer KRAS_G12D MSH2 144 34 Female -0.53 -1.59 0.24 764.50 1.01 883 142 32 2 TRUE 0.57
colorectal cancer KRAS_G12D MSH2 158 49 Male -0.34 -1.19 0.43 1163.59 1.00 1045 152 43 6 TRUE 0.39
non-small cell lung cancer KRAS_G12D MSH2 104 26 Female -0.49 -2.61 0.97 1569.55 1.00 2018 103 25 1 TRUE 0.23
non-small cell lung cancer KRAS_G12D MSH2 48 30 Male -0.41 -2.40 1.12 1480.35 1.00 1477 47 29 1 TRUE 0.18
uterine cancer KRAS_G12D MSH2 54 66 Female 0.12 -1.07 1.09 1558.91 1.00 1011 50 62 4 TRUE 0.09
colorectal cancer KRAS_G12D MSH2 302 83 Sex:overall -0.43 -1.43 0.42 880.57 1.00 1928 294 75 8 TRUE 0.42
non-small cell lung cancer KRAS_G12D MSH2 152 56 Sex:overall -0.44 -2.69 1.33 1502.78 1.00 3495 150 54 2 TRUE 0.18
uterine cancer KRAS_G12D MSH2 54 66 Sex:overall 0.13 -4.23 4.82 1512.26 1.00 1011 50 62 4 TRUE 0.02
non-small cell lung cancer KRAS_G12D DIS3 104 29 Female -0.29 -2.25 1.15 1451.08 1.00 2016 102 27 2 FALSE 0.14
non-small cell lung cancer KRAS_G12D DIS3 48 36 Male -1.13 -4.42 0.76 1519.80 1.00 1468 48 36 0 FALSE 0.40
non-small cell lung cancer KRAS_G12D DIS3 152 65 Sex:overall -0.71 -3.42 1.14 1472.89 1.00 3484 150 63 2 FALSE 0.28
colorectal cancer KRAS_G12D AXL 144 30 Female -0.49 -1.52 0.48 1187.86 1.00 882 140 26 4 FALSE 0.48
colorectal cancer KRAS_G12D AXL 158 58 Male -0.78 -1.77 0.07 1348.68 1.00 1033 155 55 3 FALSE 0.99
colorectal cancer KRAS_G12D AXL 302 88 Sex:overall -0.62 -1.74 0.48 1491.76 1.00 1915 295 81 7 FALSE 0.53
pancreatic cancer KRAS_G12D DAXX 228 21 Female -2.60 -4.39 -1.11 1000.12 1.00 450 226 19 2 TRUE 2.84
pancreatic cancer KRAS_G12D DAXX 253 32 Male -3.08 -5.71 -1.63 1113.70 1.00 495 253 32 0 TRUE 1.91
pancreatic cancer KRAS_G12D DAXX 481 53 Sex:overall -2.80 -4.86 -1.26 1240.61 1.00 945 479 51 2 TRUE 2.28
colorectal cancer KRAS_G12D PIK3CG 144 39 Female -0.54 -1.92 0.33 1155.39 1.00 871 142 37 2 FALSE 0.46
colorectal cancer KRAS_G12D PIK3CG 160 68 Male 0.06 -0.63 0.75 1176.00 1.00 1029 149 57 11 FALSE 0.07
non-small cell lung cancer KRAS_G12D PIK3CG 104 88 Female -2.28 -5.86 -0.46 1127.67 1.00 1960 104 88 0 FALSE 1.00
non-small cell lung cancer KRAS_G12D PIK3CG 48 92 Male -1.21 -3.03 0.27 988.05 1.00 1426 46 90 2 FALSE 0.79
uterine cancer KRAS_G12D PIK3CG 54 51 Female 0.06 -1.35 1.22 1205.66 1.00 1018 51 48 3 FALSE 0.03
colorectal cancer KRAS_G12D PIK3CG 304 107 Sex:overall -0.24 -1.61 0.88 1257.53 1.00 1900 291 94 13 FALSE 0.16
non-small cell lung cancer KRAS_G12D PIK3CG 152 180 Sex:overall -1.68 -3.98 0.20 1079.89 1.00 3386 150 178 2 FALSE 0.93
uterine cancer KRAS_G12D PIK3CG 54 51 Sex:overall 0.05 -4.40 4.44 1305.98 1.00 1018 51 48 3 FALSE 0.01
colorectal cancer KRAS_G12D MAP2K4 144 28 Female -1.02 -2.43 0.00 1381.56 1.00 880 143 27 1 TRUE 0.98
colorectal cancer KRAS_G12D MAP2K4 159 35 Male -0.90 -2.16 0.10 1322.11 1.00 1044 156 32 3 TRUE 0.94
colorectal cancer KRAS_G12D MAP2K4 303 63 Sex:overall -0.96 -2.29 0.11 1375.41 1.00 1924 299 59 4 TRUE 0.91
colorectal cancer KRAS_G12D EGFR 160 28 Female -1.50 -2.84 -0.24 13.10 1.13 968 159 27 1 TRUE 1.44
colorectal cancer KRAS_G12D EGFR 183 38 Male -1.48 -2.73 -0.23 11.37 1.15 1148 181 36 2 TRUE 1.45
non-small cell lung cancer KRAS_G12D EGFR 107 724 Female -3.24 -4.65 -2.17 1429.22 1.00 1520 105 722 2 TRUE 6.31
non-small cell lung cancer KRAS_G12D EGFR 50 318 Male -3.00 -4.73 -1.50 1616.61 1.00 1292 49 317 1 TRUE 3.63
colorectal cancer KRAS_G12D EGFR 343 66 Sex:overall -1.49 -2.81 -0.21 12.48 1.13 2116 340 63 3 TRUE 1.39
non-small cell lung cancer KRAS_G12D EGFR 157 1042 Sex:overall -3.05 -4.69 -1.41 1533.88 1.00 2812 154 1039 3 TRUE 3.39
colorectal cancer KRAS_G12D ARID1B 144 70 Female -1.18 -2.24 -0.36 1333.34 1.00 849 142 68 2 TRUE 1.91
colorectal cancer KRAS_G12D ARID1B 159 70 Male -0.91 -1.71 -0.11 785.20 1.00 1022 153 64 6 TRUE 1.60
non-small cell lung cancer KRAS_G12D ARID1B 104 68 Female -0.64 -2.02 0.50 1558.56 1.00 1980 102 66 2 TRUE 0.49
non-small cell lung cancer KRAS_G12D ARID1B 48 43 Male -0.64 -2.32 0.74 1505.23 1.00 1463 47 42 1 TRUE 0.40
uterine cancer KRAS_G12D ARID1B 54 114 Female 0.72 -0.01 1.39 1490.77 1.00 976 44 104 10 TRUE 1.29
colorectal cancer KRAS_G12D ARID1B 303 140 Sex:overall -1.03 -1.94 -0.16 1240.02 1.00 1871 295 132 8 TRUE 1.44
non-small cell lung cancer KRAS_G12D ARID1B 152 111 Sex:overall -0.66 -2.33 0.77 1704.60 1.00 3443 149 108 3 TRUE 0.38
uterine cancer KRAS_G12D ARID1B 54 114 Sex:overall 0.65 -3.91 5.13 1700.37 1.00 976 44 104 10 TRUE 0.12
non-small cell lung cancer KRAS_G12D INSR 104 33 Female -1.27 -4.08 0.58 1373.41 1.00 2001 103 32 1 FALSE 0.55
non-small cell lung cancer KRAS_G12D INSR 47 22 Male -1.53 -4.82 0.68 1478.62 1.00 1477 47 22 0 FALSE 0.55
non-small cell lung cancer KRAS_G12D INSR 151 55 Sex:overall -1.38 -4.38 0.65 1501.72 1.00 3478 150 54 1 FALSE 0.53
non-small cell lung cancer KRAS_G12D NKX2-1 105 34 Female 1.25 0.41 1.99 1528.14 1.00 2016 100 29 5 TRUE 2.60
non-small cell lung cancer KRAS_G12D NKX2-1 49 41 Male 1.40 0.53 2.18 1552.61 1.00 1472 44 36 5 TRUE 3.06
non-small cell lung cancer KRAS_G12D NKX2-1 154 75 Sex:overall 1.31 0.01 2.47 1182.56 1.00 3488 144 65 10 TRUE 1.39
colorectal cancer KRAS_G12D ARID5B 144 20 Female -1.70 -5.92 0.25 1201.78 1.00 887 144 20 0 FALSE 0.52
colorectal cancer KRAS_G12D ARID5B 160 48 Male 0.08 -0.83 0.87 1426.45 1.00 1046 152 40 8 FALSE 0.07
uterine cancer KRAS_G12D ARID5B 55 81 Female 0.61 -0.35 1.45 587.05 1.00 996 48 74 7 FALSE 0.76
colorectal cancer KRAS_G12D ARID5B 304 68 Sex:overall -0.76 -3.86 1.15 1371.53 1.00 1933 296 60 8 FALSE 0.28
uterine cancer KRAS_G12D ARID5B 55 81 Sex:overall 0.50 -4.24 4.74 1492.65 1.00 996 48 74 7 FALSE 0.09
non-small cell lung cancer KRAS_G12D WT1 104 39 Female 0.32 -0.98 1.33 1451.95 1.00 2008 102 37 2 TRUE 0.23
non-small cell lung cancer KRAS_G12D WT1 49 31 Male 0.68 -0.54 1.85 1176.52 1.01 1475 46 28 3 TRUE 0.58
non-small cell lung cancer KRAS_G12D WT1 153 70 Sex:overall 0.49 -0.86 1.78 1400.03 1.00 3483 148 65 5 TRUE 0.32
non-small cell lung cancer KRAS_G12D MET 107 94 Female -1.00 -2.40 0.08 1262.04 1.00 2024 105 92 2 TRUE 0.93
non-small cell lung cancer KRAS_G12D MET 50 71 Male -1.04 -2.67 0.25 1305.71 1.00 1494 49 70 1 TRUE 0.77
uterine cancer KRAS_G12D MET 56 59 Female 0.25 -0.90 1.26 212.49 1.02 1132 52 55 4 TRUE 0.19
non-small cell lung cancer KRAS_G12D MET 157 165 Sex:overall -1.02 -2.58 0.33 1329.48 1.00 3518 154 162 3 TRUE 0.75
uterine cancer KRAS_G12D MET 56 59 Sex:overall 0.22 -3.38 3.92 1058.09 1.01 1132 52 55 4 TRUE 0.05
non-small cell lung cancer KRAS_G12D PMS1 104 29 Female -0.36 -2.29 1.09 1326.05 1.00 2016 103 28 1 TRUE 0.17
non-small cell lung cancer KRAS_G12D PMS1 48 23 Male -0.26 -2.34 1.31 1404.07 1.00 1480 47 22 1 TRUE 0.11
non-small cell lung cancer KRAS_G12D PMS1 152 52 Sex:overall -0.32 -2.37 1.43 1279.07 1.00 3496 150 50 2 TRUE 0.13
pancreatic cancer KRAS_G12D MEN1 238 36 Female -3.93 -6.28 -2.07 358.91 1.01 454 237 35 1 TRUE 3.28
pancreatic cancer KRAS_G12D MEN1 262 41 Male -4.09 -6.82 -2.22 364.69 1.01 508 262 41 0 TRUE 3.13
pancreatic cancer KRAS_G12D MEN1 500 77 Sex:overall -3.98 -6.51 -2.06 365.45 1.01 962 499 76 1 TRUE 3.22
non-small cell lung cancer KRAS_G12D PIK3C3 104 40 Female -1.62 -4.89 0.31 797.67 1.00 1994 103 39 1 FALSE 0.69
non-small cell lung cancer KRAS_G12D PIK3C3 47 36 Male -1.91 -5.36 0.28 942.66 1.00 1462 47 36 0 FALSE 0.65
non-small cell lung cancer KRAS_G12D PIK3C3 151 76 Sex:overall -1.72 -5.01 0.66 961.71 1.00 3456 150 75 1 FALSE 0.63
colorectal cancer KRAS_G12D BRAF 160 128 Female -2.31 -3.54 -1.39 880.74 1.01 873 158 126 2 TRUE 4.89
colorectal cancer KRAS_G12D BRAF 184 125 Male -2.26 -3.42 -1.38 561.34 1.01 1063 181 122 3 TRUE 5.01
non-small cell lung cancer KRAS_G12D BRAF 107 113 Female -0.83 -1.98 0.14 1569.59 1.00 1998 104 110 3 TRUE 0.87
non-small cell lung cancer KRAS_G12D BRAF 50 80 Male -0.92 -2.34 0.21 1557.41 1.00 1481 49 79 1 TRUE 0.80
colorectal cancer KRAS_G12D BRAF 344 253 Sex:overall -2.28 -3.43 -1.34 733.13 1.01 1936 339 248 5 TRUE 4.58
non-small cell lung cancer KRAS_G12D BRAF 157 193 Sex:overall -0.88 -2.36 0.29 1654.13 1.00 3479 153 189 4 TRUE 0.71
colorectal cancer KRAS_G12D B2M 141 69 Female -0.34 -1.21 0.25 823.18 1.00 840 136 64 5 FALSE 0.45
colorectal cancer KRAS_G12D B2M 157 70 Male -0.06 -0.68 0.56 1134.26 1.00 1009 146 59 11 FALSE 0.07
colorectal cancer KRAS_G12D B2M 298 139 Sex:overall -0.18 -1.04 0.49 1141.38 1.00 1849 282 123 16 FALSE 0.19
colorectal cancer KRAS_G12D TGFBR1 139 14 Female 0.02 -1.23 1.04 1230.07 1.00 867 137 12 2 FALSE 0.01
colorectal cancer KRAS_G12D TGFBR1 153 37 Male 0.18 -0.69 0.98 516.27 1.01 1023 147 31 6 FALSE 0.18
non-small cell lung cancer KRAS_G12D TGFBR1 104 36 Female -0.28 -2.03 1.10 1456.66 1.00 1997 102 34 2 FALSE 0.14
non-small cell lung cancer KRAS_G12D TGFBR1 47 15 Male -0.76 -3.94 1.19 1371.16 1.00 1483 47 15 0 FALSE 0.24
colorectal cancer KRAS_G12D TGFBR1 292 51 Sex:overall 0.09 -1.26 1.33 1433.63 1.00 1890 284 43 8 FALSE 0.05
non-small cell lung cancer KRAS_G12D TGFBR1 151 51 Sex:overall -0.49 -2.90 1.37 1251.51 1.00 3480 149 49 2 FALSE 0.19
colorectal cancer KRAS_G12D TET2 145 31 Female -0.17 -1.01 0.70 682.92 1.01 884 140 26 5 TRUE 0.16
colorectal cancer KRAS_G12D TET2 158 60 Male -0.37 -1.21 0.34 1237.94 1.00 1033 153 55 5 TRUE 0.48
non-small cell lung cancer KRAS_G12D TET2 104 38 Female -0.02 -1.60 1.23 1262.77 1.00 2009 101 35 3 TRUE 0.01
non-small cell lung cancer KRAS_G12D TET2 48 43 Male -1.00 -4.57 0.75 1350.08 1.00 1463 48 43 0 TRUE 0.31
uterine cancer KRAS_G12D TET2 53 66 Female -0.23 -1.61 0.86 1336.20 1.00 1007 50 63 3 TRUE 0.14
colorectal cancer KRAS_G12D TET2 303 91 Sex:overall -0.27 -1.26 0.74 1255.11 1.00 1917 293 81 10 TRUE 0.22
non-small cell lung cancer KRAS_G12D TET2 152 81 Sex:overall -0.46 -2.95 1.33 1428.91 1.00 3472 149 78 3 TRUE 0.17
uterine cancer KRAS_G12D TET2 53 66 Sex:overall -0.11 -4.39 4.51 1516.32 1.00 1007 50 63 3 TRUE 0.02
colorectal cancer KRAS_G12D PDGFRB 144 24 Female -0.34 -1.70 0.45 25.08 1.08 885 141 21 3 TRUE 0.26
colorectal cancer KRAS_G12D PDGFRB 158 28 Male -0.39 -1.77 0.37 23.11 1.08 1050 156 26 2 TRUE 0.31
non-small cell lung cancer KRAS_G12D PDGFRB 104 54 Female -2.12 -5.63 -0.07 1187.07 1.00 1995 104 54 0 TRUE 0.81
non-small cell lung cancer KRAS_G12D PDGFRB 48 38 Male -1.63 -4.46 0.44 1499.23 1.00 1468 47 37 1 TRUE 0.74
colorectal cancer KRAS_G12D PDGFRB 302 52 Sex:overall -0.36 -1.76 0.45 23.98 1.08 1935 297 47 5 TRUE 0.27
non-small cell lung cancer KRAS_G12D PDGFRB 152 92 Sex:overall -1.83 -4.94 0.20 1513.58 1.00 3463 151 91 1 TRUE 0.79
colorectal cancer KRAS_G12D CARD11 144 49 Female -0.74 -2.12 0.16 1206.35 1.00 861 142 47 2 FALSE 0.65
colorectal cancer KRAS_G12D CARD11 159 79 Male -0.03 -0.69 0.63 1345.02 1.00 1018 147 67 12 FALSE 0.03
non-small cell lung cancer KRAS_G12D CARD11 104 71 Female -0.76 -2.22 0.43 944.43 1.00 1977 102 69 2 FALSE 0.60
non-small cell lung cancer KRAS_G12D CARD11 48 59 Male -0.80 -2.34 0.48 1164.55 1.00 1448 47 58 1 FALSE 0.57
uterine cancer KRAS_G12D CARD11 53 55 Female -1.54 -4.18 0.27 969.37 1.00 1010 52 54 1 FALSE 0.76
colorectal cancer KRAS_G12D CARD11 303 128 Sex:overall -0.39 -1.78 0.68 1422.24 1.00 1879 289 114 14 FALSE 0.28
non-small cell lung cancer KRAS_G12D CARD11 152 130 Sex:overall -0.79 -2.44 0.54 1221.06 1.00 3425 149 127 3 FALSE 0.54
uterine cancer KRAS_G12D CARD11 53 55 Sex:overall -1.31 -5.53 3.07 1056.16 1.00 1010 52 54 1 FALSE 0.28
colorectal cancer KRAS_G12D DNMT3A 144 24 Female -1.86 -4.18 -0.45 564.24 1.00 886 144 24 0 TRUE 1.11
colorectal cancer KRAS_G12D DNMT3A 158 32 Male -1.57 -3.41 -0.22 495.87 1.00 1048 156 30 2 TRUE 1.30
non-small cell lung cancer KRAS_G12D DNMT3A 104 49 Female 0.00 -1.43 1.04 1050.46 1.00 1997 102 47 2 TRUE 0.00
non-small cell lung cancer KRAS_G12D DNMT3A 48 28 Male 0.29 -1.01 1.54 1520.19 1.00 1476 46 26 2 TRUE 0.18
colorectal cancer KRAS_G12D DNMT3A 302 56 Sex:overall -1.68 -3.74 -0.22 527.77 1.00 1934 300 54 2 TRUE 1.23
non-small cell lung cancer KRAS_G12D DNMT3A 152 77 Sex:overall 0.16 -1.32 1.48 1300.74 1.00 3473 148 73 4 TRUE 0.08
colorectal cancer KRAS_G12D MSH6 144 43 Female -0.35 -1.22 0.35 917.03 1.00 871 141 40 3 TRUE 0.39
colorectal cancer KRAS_G12D MSH6 160 57 Male -0.16 -0.94 0.52 1305.59 1.00 1038 152 49 8 TRUE 0.19
uterine cancer KRAS_G12D MSH6 55 90 Female 0.50 -0.46 1.29 721.39 1.00 997 48 83 7 TRUE 0.62
colorectal cancer KRAS_G12D MSH6 304 100 Sex:overall -0.24 -1.04 0.53 1311.73 1.00 1909 293 89 11 TRUE 0.25
uterine cancer KRAS_G12D MSH6 55 90 Sex:overall 0.48 -3.58 4.72 1591.89 1.00 997 48 83 7 TRUE 0.09
non-small cell lung cancer KRAS_G12D MAX 104 35 Female 1.54 0.75 2.31 1594.04 1.00 2004 97 28 7 FALSE 3.81
non-small cell lung cancer KRAS_G12D MAX 47 20 Male 1.36 0.22 2.42 1459.49 1.00 1480 45 18 2 FALSE 1.85
non-small cell lung cancer KRAS_G12D MAX 151 55 Sex:overall 1.43 0.19 2.52 1426.35 1.00 3484 142 46 9 FALSE 1.53
non-small cell lung cancer KRAS_G12D INPP4B 104 60 Female 0.64 -0.23 1.36 1502.97 1.00 1991 99 55 5 FALSE 0.89
non-small cell lung cancer KRAS_G12D INPP4B 49 66 Male 0.82 -0.05 1.66 1457.11 1.00 1448 44 61 5 FALSE 1.23
non-small cell lung cancer KRAS_G12D INPP4B 153 126 Sex:overall 0.72 -0.53 1.79 1564.58 1.00 3439 143 116 10 FALSE 0.66
non-small cell lung cancer KRAS_G12D NFE2L2 104 52 Female -1.24 -3.11 0.17 1288.88 1.00 1996 103 51 1 FALSE 0.86
non-small cell lung cancer KRAS_G12D NFE2L2 48 72 Male -1.15 -3.04 0.31 1547.37 1.00 1440 47 71 1 FALSE 0.73
non-small cell lung cancer KRAS_G12D NFE2L2 152 124 Sex:overall -1.20 -3.21 0.46 1629.85 1.00 3436 150 122 2 FALSE 0.66
uterine cancer KRAS_G12D SPOP 53 58 Female -1.54 -4.30 0.25 889.20 1.00 1001 52 57 1 FALSE 0.72
uterine cancer KRAS_G12D SPOP 53 58 Sex:overall -1.28 -5.80 3.24 1452.26 1.00 1001 52 57 1 FALSE 0.25
colorectal cancer KRAS_G12D SOX9 146 125 Female 0.04 -0.44 0.46 1068.04 1.00 805 131 110 15 FALSE 0.06
colorectal cancer KRAS_G12D SOX9 160 139 Male 0.18 -0.21 0.63 451.95 1.00 972 136 115 24 FALSE 0.39
colorectal cancer KRAS_G12D SOX9 306 264 Sex:overall 0.11 -0.41 0.63 1248.62 1.00 1777 267 225 39 FALSE 0.15
colorectal cancer KRAS_G12D ETV1 139 23 Female -0.50 -1.65 0.45 302.35 1.01 858 137 21 2 TRUE 0.45
colorectal cancer KRAS_G12D ETV1 152 29 Male -0.45 -1.60 0.45 321.52 1.01 1026 149 26 3 TRUE 0.41
colorectal cancer KRAS_G12D ETV1 291 52 Sex:overall -0.48 -1.69 0.47 361.50 1.01 1884 286 47 5 TRUE 0.42
colorectal cancer KRAS_G12D ARAF 144 30 Female -0.38 -1.49 0.35 23.70 1.08 883 141 27 3 FALSE 0.35
colorectal cancer KRAS_G12D ARAF 158 25 Male -0.42 -1.60 0.35 32.02 1.07 1054 156 23 2 FALSE 0.38
non-small cell lung cancer KRAS_G12D ARAF 104 55 Female -0.70 -2.66 0.67 1448.55 1.00 1999 102 53 2 FALSE 0.40
non-small cell lung cancer KRAS_G12D ARAF 48 14 Male -1.32 -5.33 0.86 1314.67 1.00 1488 48 14 0 FALSE 0.39
colorectal cancer KRAS_G12D ARAF 302 55 Sex:overall -0.41 -1.59 0.39 28.20 1.07 1937 297 50 5 FALSE 0.36
non-small cell lung cancer KRAS_G12D ARAF 152 69 Sex:overall -0.95 -3.79 1.20 1513.69 1.00 3487 150 67 2 FALSE 0.33
non-small cell lung cancer KRAS_G12D JAK2 107 33 Female -0.77 -2.69 0.71 1449.67 1.00 2075 106 32 1 TRUE 0.42
non-small cell lung cancer KRAS_G12D JAK2 50 45 Male -0.73 -2.72 0.88 1448.59 1.00 1517 49 44 1 TRUE 0.37
non-small cell lung cancer KRAS_G12D JAK2 157 78 Sex:overall -0.74 -2.88 0.99 1331.12 1.00 3592 155 76 2 TRUE 0.34
colorectal cancer KRAS_G12D SMAD2 144 43 Female 0.25 -0.46 0.82 1190.45 1.00 873 138 37 6 TRUE 0.35
colorectal cancer KRAS_G12D SMAD2 160 59 Male 0.39 -0.18 0.97 1482.00 1.00 1034 148 47 12 TRUE 0.72
colorectal cancer KRAS_G12D SMAD2 304 102 Sex:overall 0.32 -0.35 0.99 1493.77 1.00 1907 286 84 18 TRUE 0.44
non-small cell lung cancer KRAS_G12D TP63 104 34 Female -1.38 -4.12 0.39 1309.68 1.00 2000 103 33 1 FALSE 0.61
non-small cell lung cancer KRAS_G12D TP63 47 38 Male -1.82 -5.44 0.26 1161.23 1.00 1460 47 38 0 FALSE 0.64
non-small cell lung cancer KRAS_G12D TP63 151 72 Sex:overall -1.57 -4.77 0.43 1320.22 1.00 3460 150 71 1 FALSE 0.61
colorectal cancer KRAS_G12D JUN 139 32 Female -0.34 -1.47 0.53 1389.89 1.00 851 136 29 3 FALSE 0.30
colorectal cancer KRAS_G12D JUN 153 21 Male -0.20 -1.25 0.76 1333.93 1.00 1032 150 18 3 FALSE 0.15
colorectal cancer KRAS_G12D JUN 292 53 Sex:overall -0.27 -1.53 0.87 1234.43 1.00 1883 286 47 6 FALSE 0.19
colorectal cancer KRAS_G12D DNMT3B 139 25 Female -5.75 -12.23 -1.75 984.10 1.00 855 139 25 0 FALSE 1.47
colorectal cancer KRAS_G12D DNMT3B 152 39 Male -5.77 -12.13 -1.85 1054.74 1.00 1016 152 39 0 FALSE 1.48
colorectal cancer KRAS_G12D DNMT3B 291 64 Sex:overall -5.71 -12.19 -1.77 1022.35 1.00 1871 291 64 0 FALSE 1.48
non-small cell lung cancer KRAS_G12D MYOD1 104 29 Female -0.52 -2.52 0.94 1309.50 1.00 2007 103 28 1 FALSE 0.25
non-small cell lung cancer KRAS_G12D MYOD1 47 29 Male -0.41 -2.45 1.16 1465.15 1.00 1470 46 28 1 FALSE 0.18
non-small cell lung cancer KRAS_G12D MYOD1 151 58 Sex:overall -0.44 -2.55 1.23 1303.24 1.00 3477 149 56 2 FALSE 0.19
colorectal cancer KRAS_G12D FGFR1 160 21 Female -0.14 -1.23 0.70 1517.90 1.00 974 158 19 2 TRUE 0.11
colorectal cancer KRAS_G12D FGFR1 183 30 Male -0.02 -0.86 0.81 1409.56 1.00 1160 178 25 5 TRUE 0.02
colorectal cancer KRAS_G12D FGFR1 343 51 Sex:overall -0.08 -1.11 0.80 1491.24 1.00 2134 336 44 7 TRUE 0.06
colorectal cancer KRAS_G12D MITF 144 22 Female 0.10 -0.89 0.90 1110.85 1.00 887 141 19 3 FALSE 0.08
colorectal cancer KRAS_G12D MITF 158 30 Male 0.16 -0.73 0.96 1027.46 1.00 1051 153 25 5 FALSE 0.15
colorectal cancer KRAS_G12D MITF 302 52 Sex:overall 0.12 -0.89 0.96 1086.32 1.00 1938 294 44 8 FALSE 0.10
non-small cell lung cancer KRAS_G12D BTK 104 47 Female -1.45 -4.25 0.37 1508.74 1.00 1998 103 46 1 TRUE 0.69
non-small cell lung cancer KRAS_G12D BTK 48 13 Male -1.80 -5.66 0.75 1326.45 1.00 1489 48 13 0 TRUE 0.55
non-small cell lung cancer KRAS_G12D BTK 152 60 Sex:overall -1.57 -4.72 0.81 1414.34 1.00 3487 151 59 1 TRUE 0.57
colorectal cancer KRAS_G12D SH2B3 128 18 Female -0.46 -1.94 0.54 1195.03 1.00 811 127 17 1 FALSE 0.33
colorectal cancer KRAS_G12D SH2B3 148 38 Male -0.02 -0.96 0.81 1243.94 1.00 957 142 32 6 FALSE 0.02
colorectal cancer KRAS_G12D SH2B3 276 56 Sex:overall -0.22 -1.66 0.96 1488.21 1.00 1768 269 49 7 FALSE 0.13
colorectal cancer KRAS_G12D GLI1 128 32 Female -0.49 -1.53 0.35 1363.69 1.00 800 126 30 2 FALSE 0.51
colorectal cancer KRAS_G12D GLI1 149 55 Male -0.27 -1.04 0.46 1183.65 1.00 941 142 48 7 FALSE 0.32
non-small cell lung cancer KRAS_G12D GLI1 97 56 Female -0.44 -1.82 0.66 1340.03 1.00 1796 94 53 3 FALSE 0.30
non-small cell lung cancer KRAS_G12D GLI1 43 50 Male -1.12 -4.43 0.41 1285.59 1.00 1302 43 50 0 FALSE 0.42
colorectal cancer KRAS_G12D GLI1 277 87 Sex:overall -0.37 -1.36 0.53 1505.31 1.00 1741 268 78 9 FALSE 0.34
non-small cell lung cancer KRAS_G12D GLI1 140 106 Sex:overall -0.77 -2.92 0.78 1339.09 1.00 3098 137 103 3 FALSE 0.37
colorectal cancer KRAS_G12D ZFHX3 129 96 Female -0.16 -0.70 0.30 1434.44 1.00 767 119 86 10 FALSE 0.28
colorectal cancer KRAS_G12D ZFHX3 150 130 Male -0.08 -0.55 0.39 1244.21 1.00 910 133 113 17 FALSE 0.13
non-small cell lung cancer KRAS_G12D ZFHX3 97 90 Female -0.21 -1.30 0.68 1159.05 1.00 1766 92 85 5 FALSE 0.17
non-small cell lung cancer KRAS_G12D ZFHX3 43 74 Male -1.31 -5.29 0.36 1230.25 1.00 1275 43 74 0 FALSE 0.41
uterine cancer KRAS_G12D ZFHX3 54 215 Female 0.35 -0.32 0.94 937.48 1.00 822 40 201 14 FALSE 0.55
colorectal cancer KRAS_G12D ZFHX3 279 226 Sex:overall -0.12 -0.70 0.40 1311.66 1.00 1677 252 199 27 FALSE 0.17
non-small cell lung cancer KRAS_G12D ZFHX3 140 164 Sex:overall -0.74 -3.45 0.85 1422.16 1.00 3041 135 159 5 FALSE 0.31
uterine cancer KRAS_G12D ZFHX3 54 215 Sex:overall 0.33 -3.94 4.78 1329.56 1.00 822 40 201 14 FALSE 0.06
colorectal cancer KRAS_G12D MST1R 123 28 Female -0.59 -2.38 0.43 1124.37 1.00 779 122 27 1 FALSE 0.40
colorectal cancer KRAS_G12D MST1R 143 45 Male 0.04 -0.76 0.81 759.88 1.01 926 135 37 8 FALSE 0.04
colorectal cancer KRAS_G12D MST1R 266 73 Sex:overall -0.27 -1.76 0.80 1286.09 1.00 1705 257 64 9 FALSE 0.17
colorectal cancer KRAS_G12D MGA 128 50 Female -0.50 -1.31 0.22 1249.37 1.00 789 122 44 6 FALSE 0.72
colorectal cancer KRAS_G12D MGA 147 73 Male -0.68 -1.49 0.00 973.24 1.00 926 143 69 4 FALSE 1.10
non-small cell lung cancer KRAS_G12D MGA 97 117 Female -1.71 -3.43 -0.32 1371.29 1.00 1754 95 115 2 FALSE 1.47
non-small cell lung cancer KRAS_G12D MGA 43 80 Male -2.07 -4.92 -0.40 1060.10 1.00 1268 43 80 0 FALSE 1.17
uterine cancer KRAS_G12D MGA 54 115 Female -0.30 -1.33 0.57 956.29 1.00 881 49 110 5 FALSE 0.26
colorectal cancer KRAS_G12D MGA 275 123 Sex:overall -0.59 -1.52 0.22 1224.07 1.00 1715 265 113 10 FALSE 0.69
non-small cell lung cancer KRAS_G12D MGA 140 197 Sex:overall -1.88 -4.10 -0.29 1385.95 1.00 3022 138 195 2 FALSE 1.28
uterine cancer KRAS_G12D MGA 54 115 Sex:overall -0.29 -4.44 4.16 1516.47 1.00 881 49 110 5 FALSE 0.05
colorectal cancer KRAS_G12D TCF3 123 31 Female -0.56 -1.56 0.27 1354.96 1.00 775 121 29 2 FALSE 0.63
colorectal cancer KRAS_G12D TCF3 142 37 Male -0.49 -1.43 0.33 1408.81 1.00 926 138 33 4 FALSE 0.56
colorectal cancer KRAS_G12D TCF3 265 68 Sex:overall -0.52 -1.48 0.38 1355.84 1.00 1701 259 62 6 FALSE 0.54
colorectal cancer KRAS_G12D KMT2B 83 87 Female -0.62 -1.20 -0.07 704.30 1.00 418 76 80 7 FALSE 1.39
colorectal cancer KRAS_G12D KMT2B 88 95 Male -0.57 -1.22 0.02 684.22 1.00 509 79 86 9 FALSE 1.19
non-small cell lung cancer KRAS_G12D KMT2B 60 33 Female -1.52 -4.46 0.28 1335.51 1.00 1034 59 32 1 FALSE 0.70
non-small cell lung cancer KRAS_G12D KMT2B 24 38 Male -1.96 -5.40 0.27 1322.68 1.00 712 24 38 0 FALSE 0.70
colorectal cancer KRAS_G12D KMT2B 171 182 Sex:overall -0.60 -1.30 0.06 772.11 1.00 927 155 166 16 FALSE 1.07
non-small cell lung cancer KRAS_G12D KMT2B 84 71 Sex:overall -1.69 -4.72 0.52 1311.44 1.00 1746 83 70 1 FALSE 0.66
colorectal cancer KRAS_G12D TCF7L2 130 124 Female 0.34 -0.08 0.78 992.81 1.00 735 106 100 24 FALSE 0.93
colorectal cancer KRAS_G12D TCF7L2 150 175 Male 0.19 -0.22 0.55 1227.68 1.00 848 126 151 24 FALSE 0.47
colorectal cancer KRAS_G12D TCF7L2 280 299 Sex:overall 0.27 -0.24 0.87 1350.76 1.00 1583 232 251 48 FALSE 0.43
colorectal cancer KRAS_G12D MSH3 82 46 Female -1.27 -3.13 0.02 675.28 1.00 432 81 45 1 FALSE 0.96
colorectal cancer KRAS_G12D MSH3 86 43 Male -0.40 -1.40 0.59 780.98 1.00 529 80 37 6 FALSE 0.35
colorectal cancer KRAS_G12D MSH3 168 89 Sex:overall -0.81 -2.49 0.66 1315.02 1.00 961 161 82 7 FALSE 0.53
colorectal cancer KRAS_G12D ANKRD11 124 56 Female -0.68 -1.68 0.02 1406.86 1.00 755 121 53 3 FALSE 0.99
colorectal cancer KRAS_G12D ANKRD11 144 90 Male -0.41 -1.06 0.16 1289.82 1.00 901 134 80 10 FALSE 0.68
non-small cell lung cancer KRAS_G12D ANKRD11 98 40 Female 0.41 -0.68 1.34 1395.70 1.00 1801 95 37 3 FALSE 0.37
non-small cell lung cancer KRAS_G12D ANKRD11 42 32 Male 0.47 -0.80 1.58 1321.19 1.00 1313 40 30 2 FALSE 0.36
colorectal cancer KRAS_G12D ANKRD11 268 146 Sex:overall -0.53 -1.48 0.28 1577.57 1.00 1656 255 133 13 FALSE 0.58
non-small cell lung cancer KRAS_G12D ANKRD11 140 72 Sex:overall 0.44 -0.91 1.66 1428.93 1.00 3114 135 67 5 FALSE 0.29
colorectal cancer KRAS_G12D PGR 123 30 Female -1.93 -7.23 0.17 511.69 1.01 770 123 30 0 FALSE 0.48
colorectal cancer KRAS_G12D PGR 143 33 Male 0.26 -0.75 1.15 1137.40 1.00 936 136 26 7 FALSE 0.22
non-small cell lung cancer KRAS_G12D PGR 97 44 Female -0.20 -1.71 1.02 1106.41 1.00 1795 94 41 3 FALSE 0.11
non-small cell lung cancer KRAS_G12D PGR 42 43 Male -1.16 -4.77 0.66 1162.14 1.00 1302 42 43 0 FALSE 0.33
colorectal cancer KRAS_G12D PGR 266 63 Sex:overall -0.74 -4.01 1.24 975.13 1.00 1706 259 56 7 FALSE 0.25
non-small cell lung cancer KRAS_G12D PGR 139 87 Sex:overall -0.66 -3.23 1.01 1194.33 1.00 3097 136 84 3 FALSE 0.26
colorectal cancer KRAS_G12D PLCG2 123 31 Female -0.02 -0.80 0.67 809.08 1.00 774 119 27 4 FALSE 0.01
colorectal cancer KRAS_G12D PLCG2 143 54 Male 0.06 -0.63 0.74 589.06 1.00 917 135 46 8 FALSE 0.06
non-small cell lung cancer KRAS_G12D PLCG2 97 31 Female -5.23 -11.90 -0.80 727.69 1.00 1808 97 31 0 FALSE 1.08
non-small cell lung cancer KRAS_G12D PLCG2 42 31 Male -5.21 -11.99 -0.67 761.26 1.00 1315 42 31 0 FALSE 1.05
colorectal cancer KRAS_G12D PLCG2 266 85 Sex:overall 0.02 -0.86 0.90 1287.12 1.00 1691 254 73 12 FALSE 0.02
non-small cell lung cancer KRAS_G12D PLCG2 139 62 Sex:overall -5.12 -11.85 -0.64 728.60 1.00 3123 139 62 0 FALSE 1.03
colorectal cancer KRAS_G12D POLD1 130 49 Female -0.63 -1.44 0.11 1161.41 1.00 791 126 45 4 TRUE 0.92
colorectal cancer KRAS_G12D POLD1 148 63 Male -0.62 -1.43 0.11 1171.63 1.00 942 143 58 5 TRUE 0.96
non-small cell lung cancer KRAS_G12D POLD1 97 31 Female 0.04 -1.51 1.24 1454.59 1.00 1819 95 29 2 TRUE 0.02
non-small cell lung cancer KRAS_G12D POLD1 43 27 Male -0.01 -1.68 1.34 1341.17 1.00 1321 42 26 1 TRUE 0.00
colorectal cancer KRAS_G12D POLD1 278 112 Sex:overall -0.62 -1.46 0.17 1405.38 1.00 1733 269 103 9 TRUE 0.83
non-small cell lung cancer KRAS_G12D POLD1 140 58 Sex:overall 0.01 -1.68 1.42 1343.34 1.00 3140 137 55 3 TRUE 0.00
colorectal cancer KRAS_G12D INHBA 128 24 Female -0.08 -2.02 0.80 13.95 1.12 805 127 23 1 FALSE 0.04
colorectal cancer KRAS_G12D INHBA 147 30 Male 0.50 -0.36 1.32 546.56 1.01 963 139 22 8 FALSE 0.66
non-small cell lung cancer KRAS_G12D INHBA 97 46 Female -1.73 -4.32 0.07 1274.58 1.00 1806 96 45 1 FALSE 0.87
non-small cell lung cancer KRAS_G12D INHBA 43 41 Male -2.05 -5.34 0.02 1200.85 1.00 1308 43 41 0 FALSE 0.79
colorectal cancer KRAS_G12D INHBA 275 54 Sex:overall 0.20 -1.41 1.25 54.55 1.04 1768 266 45 9 FALSE 0.11
non-small cell lung cancer KRAS_G12D INHBA 140 87 Sex:overall -1.87 -4.72 0.19 1339.45 1.00 3114 139 86 1 FALSE 0.80
colorectal cancer KRAS_G12D PREX2 82 31 Female -0.54 -1.81 0.31 1372.06 1.00 446 80 29 2 FALSE 0.51
colorectal cancer KRAS_G12D PREX2 86 60 Male -0.05 -0.80 0.66 1412.39 1.00 519 77 51 9 FALSE 0.05
non-small cell lung cancer KRAS_G12D PREX2 60 62 Female -0.65 -2.13 0.54 1400.76 1.00 1010 58 60 2 FALSE 0.48
non-small cell lung cancer KRAS_G12D PREX2 24 43 Male -0.62 -2.25 0.70 1330.48 1.00 710 23 42 1 FALSE 0.39
colorectal cancer KRAS_G12D PREX2 168 91 Sex:overall -0.30 -1.73 0.86 1571.88 1.00 965 157 80 11 FALSE 0.19
non-small cell lung cancer KRAS_G12D PREX2 84 105 Sex:overall -0.62 -2.33 0.83 1352.77 1.00 1720 81 102 3 FALSE 0.36
colorectal cancer KRAS_G12D AMER1 144 85 Female 0.19 -0.32 0.65 931.48 1.00 844 129 70 15 FALSE 0.33
colorectal cancer KRAS_G12D AMER1 158 84 Male 0.06 -0.50 0.58 543.27 1.00 1007 148 74 10 FALSE 0.09
non-small cell lung cancer KRAS_G12D AMER1 104 104 Female -0.12 -1.05 0.70 1477.37 1.00 1961 99 99 5 FALSE 0.10
non-small cell lung cancer KRAS_G12D AMER1 48 45 Male -0.29 -1.88 0.81 1376.23 1.00 1462 47 44 1 FALSE 0.17
uterine cancer KRAS_G12D AMER1 53 56 Female -0.65 -2.40 0.83 116.39 1.03 1019 51 54 2 FALSE 0.33
colorectal cancer KRAS_G12D AMER1 302 169 Sex:overall 0.12 -0.50 0.71 1091.31 1.00 1851 277 144 25 FALSE 0.15
non-small cell lung cancer KRAS_G12D AMER1 152 149 Sex:overall -0.21 -1.57 1.03 1398.39 1.00 3423 146 143 6 FALSE 0.11
uterine cancer KRAS_G12D AMER1 53 56 Sex:overall -0.63 -5.14 4.09 1436.64 1.00 1019 51 54 2 FALSE 0.11
colorectal cancer KRAS_G12D HLA-A 123 26 Female -1.46 -5.33 0.14 817.08 1.00 777 123 26 0 FALSE 0.54
colorectal cancer KRAS_G12D HLA-A 141 25 Male -0.43 -1.66 0.90 437.19 1.01 941 137 21 4 FALSE 0.30
colorectal cancer KRAS_G12D HLA-A 264 51 Sex:overall -0.91 -3.36 0.72 1142.10 1.00 1718 260 47 4 FALSE 0.43
colorectal cancer KRAS_G12D EPHA7 128 39 Female -0.12 -0.87 0.53 531.18 1.00 797 123 34 5 FALSE 0.13
colorectal cancer KRAS_G12D EPHA7 148 51 Male -0.12 -0.85 0.51 539.43 1.00 946 142 45 6 FALSE 0.14
non-small cell lung cancer KRAS_G12D EPHA7 97 67 Female -0.64 -2.36 0.50 1181.27 1.00 1783 96 66 1 FALSE 0.40
non-small cell lung cancer KRAS_G12D EPHA7 44 62 Male 0.23 -0.94 1.38 1302.10 1.00 1292 40 58 4 FALSE 0.16
colorectal cancer KRAS_G12D EPHA7 276 90 Sex:overall -0.12 -0.96 0.60 651.00 1.00 1743 265 79 11 FALSE 0.12
non-small cell lung cancer KRAS_G12D EPHA7 141 129 Sex:overall -0.20 -1.95 1.26 1315.96 1.00 3075 136 124 5 FALSE 0.10
colorectal cancer KRAS_G12D NCOA3 128 21 Female -0.61 -2.10 0.32 265.13 1.00 808 127 20 1 TRUE 0.47
colorectal cancer KRAS_G12D NCOA3 147 35 Male -0.42 -1.51 0.43 337.81 1.00 956 143 31 4 TRUE 0.39
colorectal cancer KRAS_G12D NCOA3 275 56 Sex:overall -0.52 -1.79 0.48 394.69 1.00 1764 270 51 5 TRUE 0.39
non-small cell lung cancer KRAS_G12D DROSHA 60 26 Female -5.02 -11.90 -0.58 688.15 1.00 1024 60 26 0 FALSE 1.03
non-small cell lung cancer KRAS_G12D DROSHA 23 28 Male -4.99 -11.66 -0.54 626.41 1.00 718 23 28 0 FALSE 1.00
non-small cell lung cancer KRAS_G12D DROSHA 83 54 Sex:overall -4.90 -11.18 -0.46 635.62 1.00 1742 83 54 0 FALSE 1.03
colorectal cancer KRAS_G12D SLX4 77 20 Female -0.26 -1.41 0.73 1223.22 1.00 424 75 18 2 FALSE 0.20
colorectal cancer KRAS_G12D SLX4 79 34 Male -0.09 -1.06 0.80 1222.72 1.00 512 74 29 5 FALSE 0.07
colorectal cancer KRAS_G12D SLX4 156 54 Sex:overall -0.15 -1.30 0.86 1296.11 1.00 936 149 47 7 FALSE 0.10
colorectal cancer KRAS_G12D INPPL1 77 22 Female -1.02 -2.37 0.23 1447.94 1.00 427 75 20 2 FALSE 0.95
colorectal cancer KRAS_G12D INPPL1 79 51 Male -1.23 -2.51 -0.18 976.95 1.00 499 77 49 2 FALSE 1.40
colorectal cancer KRAS_G12D INPPL1 156 73 Sex:overall -1.11 -2.57 0.19 1564.03 1.00 926 152 69 4 FALSE 0.94
colorectal cancer KRAS_G12V SPEN 102 55 Female -2.00 -4.02 -0.46 753.16 1.00 907 100 53 2 FALSE 1.53
colorectal cancer KRAS_G12V SPEN 102 100 Male -2.81 -6.00 -1.07 1213.67 1.00 1061 102 100 0 FALSE 1.64
non-small cell lung cancer KRAS_G12V SPEN 114 56 Female -0.02 -1.20 0.94 1330.79 1.00 1988 110 52 4 FALSE 0.01
non-small cell lung cancer KRAS_G12V SPEN 55 65 Male -0.46 -2.19 0.63 1352.52 1.00 1456 54 64 1 FALSE 0.28
uterine cancer KRAS_G12V SPEN 58 120 Female -0.93 -2.34 0.12 1350.18 1.00 979 55 117 3 FALSE 0.85
colorectal cancer KRAS_G12V SPEN 204 155 Sex:overall -2.34 -4.58 -0.56 876.25 1.00 1968 202 153 2 FALSE 1.48
non-small cell lung cancer KRAS_G12V SPEN 169 121 Sex:overall -0.22 -1.88 1.05 1469.81 1.00 3444 164 116 5 FALSE 0.11
uterine cancer KRAS_G12V SPEN 58 120 Sex:overall -0.77 -4.93 3.81 1466.54 1.00 979 55 117 3 FALSE 0.15
colorectal cancer KRAS_G12V KMT2C 95 68 Female -1.49 -2.93 -0.43 1493.81 1.00 867 94 67 1 FALSE 1.67
colorectal cancer KRAS_G12V KMT2C 100 130 Male -1.12 -2.07 -0.24 1511.52 1.00 1021 95 125 5 FALSE 1.82
non-small cell lung cancer KRAS_G12V KMT2C 115 113 Female 0.74 0.22 1.36 14.83 1.11 1930 101 99 14 FALSE 1.73
non-small cell lung cancer KRAS_G12V KMT2C 55 109 Male -0.16 -1.68 0.70 30.98 1.07 1392 53 107 2 FALSE 0.10
uterine cancer KRAS_G12V KMT2C 56 151 Female -0.56 -1.62 0.26 1367.00 1.00 906 51 146 5 FALSE 0.62
colorectal cancer KRAS_G12V KMT2C 195 198 Sex:overall -1.30 -2.70 -0.09 1576.77 1.00 1888 189 192 6 FALSE 1.21
non-small cell lung cancer KRAS_G12V KMT2C 170 222 Sex:overall 0.28 -1.16 1.57 1405.13 1.00 3322 154 206 16 FALSE 0.16
uterine cancer KRAS_G12V KMT2C 56 151 Sex:overall -0.42 -4.50 4.16 1413.48 1.00 906 51 146 5 FALSE 0.08
cancer of unknown primary KRAS_G12V TP53 30 223 Female 0.03 -0.68 0.69 1364.39 1.00 207 17 210 13 TRUE 0.03
cancer of unknown primary KRAS_G12V TP53 22 197 Male 0.41 -0.33 1.36 1227.69 1.00 209 7 182 15 TRUE 0.50
colorectal cancer KRAS_G12V TP53 115 796 Female -0.72 -1.03 -0.42 1271.08 1.00 360 56 737 59 TRUE 5.45
colorectal cancer KRAS_G12V TP53 117 923 Male -0.79 -1.11 -0.51 916.46 1.00 440 64 870 53 TRUE 6.57
non-small cell lung cancer KRAS_G12V TP53 119 1120 Female -0.56 -0.92 -0.21 1441.39 1.00 1099 75 1076 44 TRUE 2.56
non-small cell lung cancer KRAS_G12V TP53 59 936 Male -0.80 -1.28 -0.36 1468.78 1.00 699 38 915 21 TRUE 3.17
pancreatic cancer KRAS_G12V TP53 187 449 Female 0.73 0.46 1.00 1384.40 1.00 256 55 317 132 TRUE 6.59
pancreatic cancer KRAS_G12V TP53 214 497 Male 0.77 0.51 1.04 1120.76 1.00 283 57 340 157 TRUE 7.86
uterine cancer KRAS_G12V TP53 67 541 Female -1.32 -2.00 -0.72 1093.21 1.00 677 55 529 12 TRUE 4.24
cancer of unknown primary KRAS_G12V TP53 52 420 Sex:overall 0.22 -0.70 1.18 1521.92 1.00 416 24 392 28 TRUE 0.18
colorectal cancer KRAS_G12V TP53 232 1719 Sex:overall -0.76 -1.17 -0.40 1058.14 1.00 800 120 1607 112 TRUE 3.58
non-small cell lung cancer KRAS_G12V TP53 178 2056 Sex:overall -0.68 -1.47 0.05 1456.51 1.00 1798 113 1991 65 TRUE 1.14
pancreatic cancer KRAS_G12V TP53 401 946 Sex:overall 0.75 0.41 1.08 1507.45 1.00 539 112 657 289 TRUE 4.67
uterine cancer KRAS_G12V TP53 67 541 Sex:overall -1.08 -5.23 4.14 1566.05 1.00 677 55 529 12 TRUE 0.22
colorectal cancer KRAS_G12V ATRX 102 73 Female -0.76 -1.78 0.09 1466.11 1.00 891 98 69 4 TRUE 0.96
colorectal cancer KRAS_G12V ATRX 102 46 Male -0.84 -2.03 0.22 1446.35 1.00 1096 100 44 2 TRUE 0.85
non-small cell lung cancer KRAS_G12V ATRX 115 162 Female 0.08 -0.63 0.73 1530.44 1.00 1906 105 152 10 TRUE 0.09
non-small cell lung cancer KRAS_G12V ATRX 55 46 Male -0.38 -2.03 0.83 1726.61 1.00 1452 54 45 1 TRUE 0.22
uterine cancer KRAS_G12V ATRX 58 176 Female -2.70 -5.37 -0.99 1304.79 1.01 956 57 175 1 TRUE 1.91
colorectal cancer KRAS_G12V ATRX 204 119 Sex:overall -0.78 -2.12 0.49 1598.45 1.00 1987 198 113 6 TRUE 0.62
non-small cell lung cancer KRAS_G12V ATRX 170 208 Sex:overall -0.14 -1.76 1.24 1576.37 1.00 3358 159 197 11 TRUE 0.07
uterine cancer KRAS_G12V ATRX 58 176 Sex:overall -2.35 -7.08 2.62 1227.77 1.00 956 57 175 1 TRUE 0.55
colorectal cancer KRAS_G12V ATR 102 30 Female -1.11 -2.85 0.32 1477.13 1.00 922 100 28 2 FALSE 0.81
colorectal cancer KRAS_G12V ATR 102 84 Male -1.75 -3.49 -0.49 1417.12 1.00 1077 101 83 1 FALSE 1.57
non-small cell lung cancer KRAS_G12V ATR 114 69 Female -1.27 -3.12 0.05 1194.86 1.00 1969 112 67 2 FALSE 0.95
non-small cell lung cancer KRAS_G12V ATR 55 60 Male -1.70 -4.18 -0.10 865.36 1.00 1437 55 60 0 FALSE 0.90
uterine cancer KRAS_G12V ATR 58 98 Female -6.10 -15.16 -1.36 1101.44 1.00 993 58 98 0 FALSE 0.98
colorectal cancer KRAS_G12V ATR 204 114 Sex:overall -1.39 -3.27 0.41 1437.90 1.00 1999 201 111 3 FALSE 0.88
non-small cell lung cancer KRAS_G12V ATR 169 129 Sex:overall -1.46 -3.50 0.08 1201.45 1.00 3406 167 127 2 FALSE 0.93
uterine cancer KRAS_G12V ATR 58 98 Sex:overall -4.59 -12.19 2.36 1252.27 1.00 993 58 98 0 FALSE 0.73
colorectal cancer KRAS_G12V PDGFRA 113 28 Female -0.18 -1.29 0.76 1243.90 1.00 1014 110 25 3 TRUE 0.14
colorectal cancer KRAS_G12V PDGFRA 113 32 Male -0.26 -1.43 0.74 1368.37 1.00 1225 111 30 2 TRUE 0.19
non-small cell lung cancer KRAS_G12V PDGFRA 118 69 Female -0.77 -2.21 0.41 1525.02 1.00 2034 115 66 3 TRUE 0.63
non-small cell lung cancer KRAS_G12V PDGFRA 58 79 Male -1.75 -5.12 -0.08 1273.86 1.00 1476 58 79 0 TRUE 0.63
colorectal cancer KRAS_G12V PDGFRA 226 60 Sex:overall -0.22 -1.45 0.90 1303.84 1.00 2239 221 55 5 TRUE 0.14
non-small cell lung cancer KRAS_G12V PDGFRA 176 148 Sex:overall -1.22 -3.67 0.48 1367.32 1.00 3510 173 145 3 TRUE 0.58
colorectal cancer KRAS_G12V FBXW7 113 137 Female -0.37 -0.93 0.26 1371.83 1.00 931 101 125 12 TRUE 0.65
colorectal cancer KRAS_G12V FBXW7 115 202 Male -0.67 -1.34 -0.09 1407.72 1.00 1081 107 194 8 TRUE 1.45
non-small cell lung cancer KRAS_G12V FBXW7 118 39 Female 0.04 -1.23 1.09 1163.41 1.00 2064 115 36 3 TRUE 0.02
non-small cell lung cancer KRAS_G12V FBXW7 58 47 Male -0.31 -1.92 0.90 1414.96 1.00 1506 57 46 1 TRUE 0.17
uterine cancer KRAS_G12V FBXW7 66 145 Female -0.87 -2.02 0.04 1441.87 1.00 1031 62 141 4 TRUE 0.96
colorectal cancer KRAS_G12V FBXW7 228 339 Sex:overall -0.52 -1.33 0.29 1542.55 1.00 2012 208 319 20 TRUE 0.62
non-small cell lung cancer KRAS_G12V FBXW7 176 86 Sex:overall -0.14 -1.77 1.27 1142.69 1.00 3570 172 82 4 TRUE 0.07
uterine cancer KRAS_G12V FBXW7 66 145 Sex:overall -0.73 -4.86 3.60 1339.68 1.00 1031 62 141 4 TRUE 0.14
colorectal cancer KRAS_G12V MAP3K1 102 39 Female -0.68 -1.84 0.27 852.77 1.00 916 100 37 2 FALSE 0.67
colorectal cancer KRAS_G12V MAP3K1 102 53 Male -0.62 -1.68 0.35 742.97 1.00 1087 99 50 3 FALSE 0.63
non-small cell lung cancer KRAS_G12V MAP3K1 115 39 Female -0.60 -2.27 0.66 913.60 1.00 1997 113 37 2 FALSE 0.36
non-small cell lung cancer KRAS_G12V MAP3K1 55 28 Male -0.99 -3.61 0.68 910.66 1.00 1467 55 28 0 FALSE 0.39
uterine cancer KRAS_G12V MAP3K1 58 71 Female -5.85 -14.60 -1.12 1360.52 1.00 992 58 71 0 FALSE 0.89
colorectal cancer KRAS_G12V MAP3K1 204 92 Sex:overall -0.65 -1.82 0.45 909.82 1.00 2003 199 87 5 FALSE 0.57
non-small cell lung cancer KRAS_G12V MAP3K1 170 67 Sex:overall -0.77 -2.73 0.82 978.05 1.00 3464 168 65 2 FALSE 0.38
uterine cancer KRAS_G12V MAP3K1 58 71 Sex:overall -4.52 -11.86 2.41 1301.74 1.00 992 58 71 0 FALSE 0.70
colorectal cancer KRAS_G12V NSD1 103 35 Female -0.46 -1.71 0.75 439.56 1.00 921 99 31 4 FALSE 0.34
colorectal cancer KRAS_G12V NSD1 102 51 Male -1.68 -5.23 -0.16 364.77 1.02 1089 102 51 0 FALSE 0.63
non-small cell lung cancer KRAS_G12V NSD1 114 50 Female 0.16 -0.93 1.08 1411.46 1.00 1988 110 46 4 FALSE 0.12
non-small cell lung cancer KRAS_G12V NSD1 55 40 Male -0.11 -1.63 1.01 1175.06 1.00 1456 54 39 1 FALSE 0.06
uterine cancer KRAS_G12V NSD1 59 123 Female -0.14 -1.05 0.72 1533.61 1.00 974 53 117 6 FALSE 0.12
colorectal cancer KRAS_G12V NSD1 205 86 Sex:overall -1.03 -3.49 0.73 753.67 1.01 2010 201 82 4 FALSE 0.49
non-small cell lung cancer KRAS_G12V NSD1 169 90 Sex:overall 0.03 -1.25 1.21 1437.90 1.00 3444 164 85 5 FALSE 0.02
uterine cancer KRAS_G12V NSD1 59 123 Sex:overall -0.20 -4.65 4.08 1464.32 1.00 974 53 117 6 FALSE 0.04
colorectal cancer KRAS_G12V FLT4 102 70 Female -0.85 -1.90 0.00 1399.99 1.00 892 98 66 4 TRUE 1.15
colorectal cancer KRAS_G12V FLT4 103 69 Male -0.95 -2.07 -0.09 1452.29 1.00 1071 101 67 2 TRUE 1.28
non-small cell lung cancer KRAS_G12V FLT4 114 47 Female -0.56 -2.34 0.62 1379.30 1.00 1990 113 46 1 TRUE 0.34
non-small cell lung cancer KRAS_G12V FLT4 55 55 Male -0.02 -1.31 1.12 1380.43 1.00 1444 52 52 3 TRUE 0.01
uterine cancer KRAS_G12V FLT4 58 52 Female -0.59 -2.45 0.83 1449.25 1.00 1011 56 50 2 TRUE 0.32
colorectal cancer KRAS_G12V FLT4 205 139 Sex:overall -0.90 -2.00 0.00 1354.88 1.00 1963 199 133 6 TRUE 1.10
non-small cell lung cancer KRAS_G12V FLT4 169 102 Sex:overall -0.28 -2.04 1.13 1404.46 1.00 3434 165 98 4 TRUE 0.14
uterine cancer KRAS_G12V FLT4 58 52 Sex:overall -0.46 -4.70 4.03 1272.81 1.00 1011 56 50 2 TRUE 0.08
colorectal cancer KRAS_G12V PTPRD 102 48 Female -1.87 -3.60 -0.54 1222.41 1.00 907 101 47 1 FALSE 1.69
colorectal cancer KRAS_G12V PTPRD 102 55 Male -1.90 -3.69 -0.53 1124.55 1.00 1092 101 54 1 FALSE 1.68
non-small cell lung cancer KRAS_G12V PTPRD 116 235 Female 0.16 -0.38 0.65 515.02 1.01 1855 101 220 15 FALSE 0.25
non-small cell lung cancer KRAS_G12V PTPRD 55 156 Male 0.00 -0.74 0.62 289.71 1.01 1360 50 151 5 FALSE 0.00
uterine cancer KRAS_G12V PTPRD 58 99 Female -1.24 -3.03 0.03 1228.13 1.00 995 56 97 2 FALSE 0.95
colorectal cancer KRAS_G12V PTPRD 204 103 Sex:overall -1.88 -3.72 -0.49 1208.76 1.00 1999 202 101 2 FALSE 1.54
non-small cell lung cancer KRAS_G12V PTPRD 171 391 Sex:overall 0.07 -0.82 0.81 618.34 1.01 3215 151 371 20 FALSE 0.07
uterine cancer KRAS_G12V PTPRD 58 99 Sex:overall -1.04 -5.09 3.52 1495.80 1.00 995 56 97 2 FALSE 0.20
colorectal cancer KRAS_G12V RET 113 36 Female -1.26 -3.09 0.09 1495.26 1.00 1006 111 34 2 TRUE 0.94
colorectal cancer KRAS_G12V RET 113 29 Male -1.75 -4.92 -0.13 1205.58 1.00 1223 113 29 0 TRUE 0.75
non-small cell lung cancer KRAS_G12V RET 118 55 Female 0.48 -0.41 1.31 1286.71 1.00 2046 113 50 5 TRUE 0.57
non-small cell lung cancer KRAS_G12V RET 58 38 Male 0.40 -0.69 1.38 1319.71 1.00 1517 56 36 2 TRUE 0.36
colorectal cancer KRAS_G12V RET 226 65 Sex:overall -1.49 -3.83 0.16 1093.84 1.00 2229 224 63 2 TRUE 0.85
non-small cell lung cancer KRAS_G12V RET 176 93 Sex:overall 0.44 -0.70 1.45 1473.86 1.00 3563 169 86 7 TRUE 0.33
colorectal cancer KRAS_G12V KDM5A 102 31 Female -2.21 -5.17 -0.46 1415.39 1.00 919 102 31 0 FALSE 1.00
colorectal cancer KRAS_G12V KDM5A 102 65 Male -1.63 -3.50 -0.35 1433.87 1.00 1084 100 63 2 FALSE 1.37
non-small cell lung cancer KRAS_G12V KDM5A 114 37 Female 0.66 -0.49 1.65 1553.76 1.00 2002 109 32 5 FALSE 0.63
non-small cell lung cancer KRAS_G12V KDM5A 55 36 Male -0.71 -4.55 1.09 1285.38 1.00 1462 55 36 0 FALSE 0.17
uterine cancer KRAS_G12V KDM5A 58 65 Female -0.84 -2.63 0.61 851.83 1.00 1004 56 63 2 FALSE 0.50
colorectal cancer KRAS_G12V KDM5A 204 96 Sex:overall -1.89 -4.37 -0.16 1441.14 1.00 2003 202 94 2 FALSE 1.07
non-small cell lung cancer KRAS_G12V KDM5A 169 73 Sex:overall -0.03 -3.10 1.68 1471.07 1.00 3464 164 68 5 FALSE 0.01
uterine cancer KRAS_G12V KDM5A 58 65 Sex:overall -0.76 -5.01 3.53 1317.35 1.00 1004 56 63 2 FALSE 0.15
colorectal cancer KRAS_G12V PIK3C2G 95 30 Female -0.14 -1.20 0.82 368.96 1.00 899 92 27 3 FALSE 0.11
colorectal cancer KRAS_G12V PIK3C2G 99 57 Male -0.22 -1.22 0.56 391.30 1.00 1060 95 53 4 FALSE 0.19
non-small cell lung cancer KRAS_G12V PIK3C2G 114 70 Female -1.95 -5.56 -0.25 1257.52 1.00 1954 114 70 0 FALSE 0.77
non-small cell lung cancer KRAS_G12V PIK3C2G 55 61 Male -1.07 -3.01 0.49 1370.83 1.00 1436 53 59 2 FALSE 0.65
colorectal cancer KRAS_G12V PIK3C2G 194 87 Sex:overall -0.16 -1.26 0.89 539.19 1.00 1959 187 80 7 FALSE 0.11
non-small cell lung cancer KRAS_G12V PIK3C2G 169 131 Sex:overall -1.46 -3.90 0.35 1255.38 1.00 3390 167 129 2 FALSE 0.71
non-small cell lung cancer KRAS_G12V TSHR 114 47 Female -0.17 -1.52 0.94 861.61 1.00 1992 111 44 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V TSHR 55 22 Male -0.77 -3.98 0.88 1130.58 1.00 1473 55 22 0 TRUE 0.28
non-small cell lung cancer KRAS_G12V TSHR 169 69 Sex:overall -0.45 -2.75 1.03 938.93 1.00 3465 166 66 3 TRUE 0.19
colorectal cancer KRAS_G12V CREBBP 102 81 Female -1.00 -1.86 -0.18 1059.86 1.00 890 98 77 4 TRUE 1.69
colorectal cancer KRAS_G12V CREBBP 102 107 Male -1.06 -1.99 -0.27 978.51 1.00 1054 99 104 3 TRUE 1.82
non-small cell lung cancer KRAS_G12V CREBBP 114 82 Female 0.36 -0.41 1.08 1255.03 1.00 1964 107 75 7 TRUE 0.45
non-small cell lung cancer KRAS_G12V CREBBP 55 60 Male 0.17 -0.85 0.99 1395.09 1.00 1441 53 58 2 TRUE 0.14
uterine cancer KRAS_G12V CREBBP 59 95 Female -0.08 -1.19 0.85 362.82 1.01 986 54 90 5 TRUE 0.05
colorectal cancer KRAS_G12V CREBBP 204 188 Sex:overall -1.02 -2.01 -0.17 910.37 1.00 1944 197 181 7 TRUE 1.51
non-small cell lung cancer KRAS_G12V CREBBP 169 142 Sex:overall 0.27 -0.76 1.14 1392.45 1.00 3405 160 133 9 TRUE 0.23
uterine cancer KRAS_G12V CREBBP 59 95 Sex:overall -0.12 -4.71 4.21 1413.57 1.00 986 54 90 5 TRUE 0.02
non-small cell lung cancer KRAS_G12V BRIP1 114 36 Female -1.52 -4.08 0.34 699.26 1.00 1999 113 35 1 TRUE 0.71
non-small cell lung cancer KRAS_G12V BRIP1 55 34 Male -1.82 -4.82 0.21 629.02 1.00 1461 55 34 0 TRUE 0.76
non-small cell lung cancer KRAS_G12V BRIP1 169 70 Sex:overall -1.66 -4.63 0.31 714.46 1.00 3460 168 69 1 TRUE 0.70
colorectal cancer KRAS_G12V AXIN2 102 48 Female -1.03 -2.25 0.00 1101.32 1.00 912 99 45 3 TRUE 1.10
colorectal cancer KRAS_G12V AXIN2 102 67 Male -1.24 -2.66 -0.22 1010.43 1.00 1074 101 66 1 TRUE 1.33
non-small cell lung cancer KRAS_G12V AXIN2 114 31 Female 0.91 -0.13 1.86 1350.82 1.00 2007 109 26 5 TRUE 1.14
non-small cell lung cancer KRAS_G12V AXIN2 55 31 Male 0.41 -1.34 1.53 1591.12 1.00 1465 54 30 1 TRUE 0.25
uterine cancer KRAS_G12V AXIN2 58 52 Female -0.55 -2.19 0.79 1106.03 1.00 1007 56 50 2 TRUE 0.31
colorectal cancer KRAS_G12V AXIN2 204 115 Sex:overall -1.14 -2.49 -0.04 1145.92 1.00 1986 200 111 4 TRUE 1.13
non-small cell lung cancer KRAS_G12V AXIN2 169 62 Sex:overall 0.64 -1.03 2.10 1507.36 1.00 3472 163 56 6 TRUE 0.39
uterine cancer KRAS_G12V AXIN2 58 52 Sex:overall -0.44 -4.55 4.27 1280.87 1.00 1007 56 50 2 TRUE 0.08
colorectal cancer KRAS_G12V DOT1L 102 30 Female -1.57 -4.36 -0.17 1377.19 1.00 920 102 30 0 FALSE 0.77
colorectal cancer KRAS_G12V DOT1L 102 54 Male -0.96 -2.37 0.17 1382.81 1.00 1091 99 51 3 FALSE 0.85
non-small cell lung cancer KRAS_G12V DOT1L 114 46 Female 0.15 -1.04 1.18 1553.79 1.00 1992 110 42 4 FALSE 0.11
non-small cell lung cancer KRAS_G12V DOT1L 55 61 Male -0.44 -2.05 0.76 1277.38 1.00 1437 54 60 1 FALSE 0.26
colorectal cancer KRAS_G12V DOT1L 204 84 Sex:overall -1.22 -3.13 0.28 1372.68 1.00 2011 201 81 3 FALSE 0.75
non-small cell lung cancer KRAS_G12V DOT1L 169 107 Sex:overall -0.12 -1.76 1.51 1371.88 1.00 3429 164 102 5 FALSE 0.05
colorectal cancer KRAS_G12V PTPRS 95 107 Female -0.55 -1.21 0.11 890.72 1.00 842 87 99 8 FALSE 0.99
colorectal cancer KRAS_G12V PTPRS 99 147 Male -0.72 -1.46 -0.09 1103.74 1.00 991 94 142 5 FALSE 1.38
non-small cell lung cancer KRAS_G12V PTPRS 114 43 Female 0.38 -0.66 1.25 1047.73 1.00 1983 111 40 3 FALSE 0.35
non-small cell lung cancer KRAS_G12V PTPRS 55 37 Male 0.56 -0.56 1.60 1471.65 1.00 1460 52 34 3 FALSE 0.52
uterine cancer KRAS_G12V PTPRS 57 79 Female -0.55 -1.90 0.59 1306.89 1.00 935 54 76 3 FALSE 0.40
colorectal cancer KRAS_G12V PTPRS 194 254 Sex:overall -0.64 -1.45 0.12 1093.44 1.00 1833 181 241 13 FALSE 0.94
non-small cell lung cancer KRAS_G12V PTPRS 169 80 Sex:overall 0.46 -0.77 1.66 1316.64 1.00 3443 163 74 6 FALSE 0.35
uterine cancer KRAS_G12V PTPRS 57 79 Sex:overall -0.47 -4.99 4.06 1476.26 1.00 935 54 76 3 FALSE 0.08
colorectal cancer KRAS_G12V SMARCA4 102 77 Female -1.91 -3.33 -0.72 165.43 1.02 887 100 75 2 FALSE 2.50
colorectal cancer KRAS_G12V SMARCA4 102 92 Male -2.00 -3.44 -0.83 292.27 1.01 1064 101 91 1 FALSE 2.62
non-small cell lung cancer KRAS_G12V SMARCA4 114 163 Female 0.46 -0.09 0.97 1007.08 1.00 1898 101 150 13 FALSE 1.04
non-small cell lung cancer KRAS_G12V SMARCA4 55 150 Male 0.44 -0.22 1.07 1675.20 1.00 1360 47 142 8 FALSE 0.73
uterine cancer KRAS_G12V SMARCA4 58 102 Female -1.23 -2.89 0.13 1186.10 1.00 981 56 100 2 FALSE 0.96
colorectal cancer KRAS_G12V SMARCA4 204 169 Sex:overall -1.95 -3.39 -0.67 215.74 1.01 1951 201 166 3 FALSE 2.34
non-small cell lung cancer KRAS_G12V SMARCA4 169 313 Sex:overall 0.45 -0.45 1.34 1664.18 1.00 3258 148 292 21 FALSE 0.44
uterine cancer KRAS_G12V SMARCA4 58 102 Sex:overall -1.04 -5.35 3.71 1428.34 1.00 981 56 100 2 FALSE 0.20
colorectal cancer KRAS_G12V PTPRT 102 71 Female -0.39 -1.18 0.27 1497.02 1.00 887 97 66 5 FALSE 0.55
colorectal cancer KRAS_G12V PTPRT 102 114 Male -0.38 -1.05 0.25 1444.98 1.00 1040 95 107 7 FALSE 0.57
non-small cell lung cancer KRAS_G12V PTPRT 115 205 Female -0.12 -0.74 0.46 1447.04 1.00 1873 106 196 9 FALSE 0.15
non-small cell lung cancer KRAS_G12V PTPRT 56 146 Male 0.07 -0.64 0.79 1464.63 1.00 1380 49 139 7 FALSE 0.08
uterine cancer KRAS_G12V PTPRT 58 87 Female -1.11 -2.83 0.18 1524.79 1.00 987 56 85 2 FALSE 0.80
colorectal cancer KRAS_G12V PTPRT 204 185 Sex:overall -0.40 -1.28 0.40 1702.87 1.00 1927 192 173 12 FALSE 0.40
non-small cell lung cancer KRAS_G12V PTPRT 171 351 Sex:overall -0.02 -0.82 0.86 1495.63 1.00 3253 155 335 16 FALSE 0.02
uterine cancer KRAS_G12V PTPRT 58 87 Sex:overall -0.91 -5.33 3.86 1433.84 1.00 987 56 85 2 FALSE 0.18
colorectal cancer KRAS_G12V HGF 102 14 Female -2.48 -6.26 -0.13 1404.12 1.00 935 102 14 0 FALSE 0.92
colorectal cancer KRAS_G12V HGF 102 42 Male -2.08 -4.88 -0.24 1320.00 1.00 1094 101 41 1 FALSE 1.08
non-small cell lung cancer KRAS_G12V HGF 114 108 Female -0.26 -1.20 0.56 1130.72 1.00 1937 109 103 5 FALSE 0.26
non-small cell lung cancer KRAS_G12V HGF 55 83 Male -0.35 -1.45 0.54 870.06 1.00 1420 53 81 2 FALSE 0.31
colorectal cancer KRAS_G12V HGF 204 56 Sex:overall -2.23 -5.48 0.10 1349.24 1.00 2029 203 55 1 FALSE 0.90
non-small cell lung cancer KRAS_G12V HGF 169 191 Sex:overall -0.31 -1.52 0.76 1172.51 1.00 3357 162 184 7 FALSE 0.23
colorectal cancer KRAS_G12V BLM 102 26 Female -1.40 -3.12 0.06 325.77 1.01 925 101 25 1 TRUE 1.03
colorectal cancer KRAS_G12V BLM 102 44 Male -1.46 -3.10 0.00 350.08 1.00 1095 101 43 1 TRUE 1.14
colorectal cancer KRAS_G12V BLM 204 70 Sex:overall -1.43 -3.26 0.01 373.25 1.01 2020 202 68 2 TRUE 1.01
colorectal cancer KRAS_G12V PIK3CA 115 244 Female 0.36 -0.01 0.72 1379.85 1.00 847 85 214 30 TRUE 1.24
colorectal cancer KRAS_G12V PIK3CA 115 267 Male 0.36 0.00 0.71 1279.38 1.00 1043 86 238 29 TRUE 1.32
non-small cell lung cancer KRAS_G12V PIK3CA 118 141 Female -0.39 -1.25 0.33 1383.49 1.00 1968 112 135 6 TRUE 0.49
non-small cell lung cancer KRAS_G12V PIK3CA 58 101 Male -0.52 -1.66 0.39 1373.37 1.00 1453 56 99 2 TRUE 0.52
uterine cancer KRAS_G12V PIK3CA 75 557 Female 0.00 -0.49 0.47 835.68 1.00 753 44 526 31 TRUE 0.00
colorectal cancer KRAS_G12V PIK3CA 230 511 Sex:overall 0.36 -0.08 0.80 1394.84 1.00 1890 171 452 59 TRUE 0.86
non-small cell lung cancer KRAS_G12V PIK3CA 176 242 Sex:overall -0.45 -1.60 0.64 1352.79 1.00 3421 168 234 8 TRUE 0.35
uterine cancer KRAS_G12V PIK3CA 75 557 Sex:overall 0.07 -4.08 4.36 1429.52 1.00 753 44 526 31 TRUE 0.01
non-small cell lung cancer KRAS_G12V GATA3 114 40 Female -0.57 -2.40 0.73 958.94 1.00 1998 112 38 2 FALSE 0.32
non-small cell lung cancer KRAS_G12V GATA3 55 26 Male -0.98 -3.78 0.73 1154.29 1.00 1470 55 26 0 FALSE 0.39
non-small cell lung cancer KRAS_G12V GATA3 169 66 Sex:overall -0.75 -3.09 0.91 1395.26 1.00 3468 167 64 2 FALSE 0.35
colorectal cancer KRAS_G12V ESR1 102 26 Female -1.46 -3.25 -0.14 529.73 1.01 925 101 25 1 TRUE 1.12
colorectal cancer KRAS_G12V ESR1 102 46 Male -1.52 -3.39 -0.18 628.70 1.00 1088 101 45 1 TRUE 1.21
non-small cell lung cancer KRAS_G12V ESR1 114 30 Female -1.46 -4.18 0.53 1001.93 1.00 2007 113 29 1 TRUE 0.62
non-small cell lung cancer KRAS_G12V ESR1 55 26 Male -1.74 -5.15 0.42 940.41 1.00 1469 55 26 0 TRUE 0.62
colorectal cancer KRAS_G12V ESR1 204 72 Sex:overall -1.47 -3.37 -0.05 652.16 1.00 2013 202 70 2 TRUE 1.06
non-small cell lung cancer KRAS_G12V ESR1 169 56 Sex:overall -1.59 -4.71 0.59 1147.22 1.00 3476 168 55 1 TRUE 0.61
colorectal cancer KRAS_G12V ALK 113 55 Female -1.42 -2.76 -0.29 587.75 1.00 991 111 53 2 TRUE 1.71
colorectal cancer KRAS_G12V ALK 113 60 Male -1.50 -2.92 -0.37 453.08 1.00 1202 112 59 1 TRUE 1.65
non-small cell lung cancer KRAS_G12V ALK 118 90 Female 0.33 -0.56 1.05 363.21 1.01 2018 110 82 8 TRUE 0.38
non-small cell lung cancer KRAS_G12V ALK 58 79 Male -0.03 -1.19 0.88 911.94 1.00 1479 56 77 2 TRUE 0.02
uterine cancer KRAS_G12V ALK 66 53 Female -5.82 -14.59 -0.83 905.88 1.01 1116 66 53 0 TRUE 0.55
colorectal cancer KRAS_G12V ALK 226 115 Sex:overall -1.45 -2.94 -0.24 663.46 1.00 2193 223 112 3 TRUE 1.56
non-small cell lung cancer KRAS_G12V ALK 176 169 Sex:overall 0.15 -1.07 1.22 1150.15 1.00 3497 166 159 10 TRUE 0.08
uterine cancer KRAS_G12V ALK 66 53 Sex:overall -4.26 -11.34 3.13 1181.51 1.00 1116 66 53 0 TRUE 0.64
colorectal cancer KRAS_G12V RNF43 102 140 Female -1.91 -3.70 -1.15 2.74 1.45 846 101 139 1 TRUE 1.84
colorectal cancer KRAS_G12V RNF43 102 127 Male -1.67 -3.29 -0.90 3.54 1.30 1039 99 124 3 TRUE 1.92
pancreatic cancer KRAS_G12V RNF43 183 34 Female 0.22 -0.38 0.78 1453.70 1.00 520 173 24 10 TRUE 0.36
pancreatic cancer KRAS_G12V RNF43 208 46 Male 0.24 -0.31 0.74 1257.79 1.00 575 194 32 14 TRUE 0.41
uterine cancer KRAS_G12V RNF43 60 95 Female -0.11 -1.17 0.76 1207.03 1.00 976 55 90 5 TRUE 0.08
colorectal cancer KRAS_G12V RNF43 204 267 Sex:overall -1.77 -3.51 -0.94 3.35 1.32 1885 200 263 4 TRUE 1.76
pancreatic cancer KRAS_G12V RNF43 391 80 Sex:overall 0.23 -0.38 0.83 1256.71 1.00 1095 367 56 24 TRUE 0.30
uterine cancer KRAS_G12V RNF43 60 95 Sex:overall -0.13 -4.32 4.49 1542.86 1.00 976 55 90 5 TRUE 0.02
non-small cell lung cancer KRAS_G12V U2AF1 114 52 Female 0.99 0.19 1.70 1324.95 1.00 1988 107 45 7 FALSE 1.94
non-small cell lung cancer KRAS_G12V U2AF1 55 26 Male 0.86 -0.24 1.77 1367.38 1.00 1473 53 24 2 FALSE 1.04
non-small cell lung cancer KRAS_G12V U2AF1 169 78 Sex:overall 0.93 -0.13 1.91 1520.34 1.00 3461 160 69 9 FALSE 1.01
colorectal cancer KRAS_G12V LATS1 95 19 Female -2.17 -5.45 -0.07 521.50 1.00 903 95 19 0 FALSE 0.88
colorectal cancer KRAS_G12V LATS1 99 36 Male -1.91 -4.75 -0.05 545.69 1.00 1074 98 35 1 FALSE 0.96
non-small cell lung cancer KRAS_G12V LATS1 114 41 Female -0.27 -1.65 0.86 1263.72 1.00 1983 112 39 2 FALSE 0.17
non-small cell lung cancer KRAS_G12V LATS1 55 27 Male -0.28 -1.84 0.96 1332.66 1.00 1464 54 26 1 FALSE 0.16
colorectal cancer KRAS_G12V LATS1 194 55 Sex:overall -2.02 -5.02 -0.09 494.21 1.00 1977 193 54 1 FALSE 0.94
non-small cell lung cancer KRAS_G12V LATS1 169 68 Sex:overall -0.26 -1.85 1.08 1451.08 1.00 3447 166 65 3 FALSE 0.14
colorectal cancer KRAS_G12V LATS2 95 26 Female -6.29 -11.79 -1.43 20.87 1.14 898 95 26 0 FALSE 1.27
colorectal cancer KRAS_G12V LATS2 99 44 Male -6.33 -11.81 -1.51 20.70 1.14 1060 99 44 0 FALSE 1.31
non-small cell lung cancer KRAS_G12V LATS2 114 30 Female -0.07 -1.67 1.14 1331.80 1.00 1995 112 28 2 FALSE 0.04
non-small cell lung cancer KRAS_G12V LATS2 55 31 Male -0.17 -1.77 1.18 1404.95 1.00 1461 54 30 1 FALSE 0.09
uterine cancer KRAS_G12V LATS2 56 54 Female -1.60 -4.48 0.29 1111.74 1.00 952 55 53 1 FALSE 0.72
colorectal cancer KRAS_G12V LATS2 194 70 Sex:overall -6.24 -11.70 -1.39 19.30 1.15 1958 194 70 0 FALSE 1.30
non-small cell lung cancer KRAS_G12V LATS2 169 61 Sex:overall -0.12 -1.85 1.37 1376.04 1.00 3456 166 58 3 FALSE 0.05
uterine cancer KRAS_G12V LATS2 56 54 Sex:overall -1.35 -5.71 3.66 1244.08 1.00 952 55 53 1 FALSE 0.27
colorectal cancer KRAS_G12V PTEN 113 80 Female -0.52 -1.26 0.14 1284.33 1.00 984 108 75 5 TRUE 0.87
colorectal cancer KRAS_G12V PTEN 113 105 Male -0.49 -1.19 0.15 1061.90 1.00 1177 107 99 6 TRUE 0.86
non-small cell lung cancer KRAS_G12V PTEN 118 60 Female -5.59 -12.67 -1.52 1115.96 1.00 2036 118 60 0 TRUE 1.25
non-small cell lung cancer KRAS_G12V PTEN 58 76 Male -5.56 -12.58 -1.51 1176.43 1.00 1480 58 76 0 TRUE 1.26
uterine cancer KRAS_G12V PTEN 81 627 Female 0.20 -0.23 0.64 1585.94 1.00 787 42 588 39 TRUE 0.45
colorectal cancer KRAS_G12V PTEN 226 185 Sex:overall -0.51 -1.29 0.19 1300.23 1.00 2161 215 174 11 TRUE 0.75
non-small cell lung cancer KRAS_G12V PTEN 176 136 Sex:overall -5.47 -12.22 -1.31 1121.79 1.00 3516 176 136 0 TRUE 1.25
uterine cancer KRAS_G12V PTEN 81 627 Sex:overall 0.04 -4.10 4.11 1506.81 1.00 787 42 588 39 TRUE 0.01
colorectal cancer KRAS_G12V BCOR 102 59 Female -0.94 -2.11 -0.02 1276.82 1.00 904 100 57 2 FALSE 1.12
colorectal cancer KRAS_G12V BCOR 102 53 Male -0.79 -1.88 0.20 1141.17 1.00 1086 99 50 3 FALSE 0.90
non-small cell lung cancer KRAS_G12V BCOR 115 103 Female 0.92 0.26 1.53 1230.18 1.00 1951 102 90 13 FALSE 2.49
non-small cell lung cancer KRAS_G12V BCOR 55 31 Male 0.28 -1.42 1.45 1396.44 1.00 1467 54 30 1 FALSE 0.15
uterine cancer KRAS_G12V BCOR 58 140 Female -0.80 -1.95 0.10 716.45 1.00 940 54 136 4 FALSE 0.85
colorectal cancer KRAS_G12V BCOR 204 112 Sex:overall -0.87 -2.12 0.10 1440.92 1.00 1990 199 107 5 FALSE 0.87
non-small cell lung cancer KRAS_G12V BCOR 170 134 Sex:overall 0.60 -1.26 2.01 1383.80 1.00 3418 156 120 14 FALSE 0.35
uterine cancer KRAS_G12V BCOR 58 140 Sex:overall -0.66 -4.68 3.70 1374.25 1.00 940 54 136 4 FALSE 0.13
colorectal cancer KRAS_G12V CTNNB1 114 74 Female -0.13 -0.82 0.53 494.62 1.00 974 106 66 8 TRUE 0.15
colorectal cancer KRAS_G12V CTNNB1 113 89 Male -0.24 -0.95 0.38 448.68 1.01 1172 108 84 5 TRUE 0.32
non-small cell lung cancer KRAS_G12V CTNNB1 118 74 Female -1.29 -3.19 0.10 1538.28 1.00 2025 116 72 2 TRUE 0.93
non-small cell lung cancer KRAS_G12V CTNNB1 58 47 Male -1.65 -4.35 -0.04 1280.70 1.00 1504 58 47 0 TRUE 0.81
uterine cancer KRAS_G12V CTNNB1 66 143 Female -0.90 -2.02 0.06 211.30 1.02 1022 62 139 4 TRUE 1.05
colorectal cancer KRAS_G12V CTNNB1 227 163 Sex:overall -0.18 -0.98 0.55 684.25 1.00 2146 214 150 13 TRUE 0.18
non-small cell lung cancer KRAS_G12V CTNNB1 176 121 Sex:overall -1.47 -3.85 0.26 1596.27 1.00 3529 174 119 2 TRUE 0.81
uterine cancer KRAS_G12V CTNNB1 66 143 Sex:overall -0.74 -4.93 4.04 1606.02 1.00 1022 62 139 4 TRUE 0.14
cancer of unknown primary KRAS_G12V ARID1A 33 65 Female 0.56 -0.36 1.38 1332.23 1.00 352 24 56 9 TRUE 0.68
cancer of unknown primary KRAS_G12V ARID1A 21 51 Male -1.49 -6.34 0.53 1077.18 1.00 323 21 51 0 TRUE 0.38
colorectal cancer KRAS_G12V ARID1A 103 149 Female -0.65 -1.27 -0.09 312.27 1.01 859 94 140 9 TRUE 1.51
colorectal cancer KRAS_G12V ARID1A 102 166 Male -0.71 -1.31 -0.14 404.76 1.01 1016 95 159 7 TRUE 1.63
non-small cell lung cancer KRAS_G12V ARID1A 116 132 Female 0.13 -0.56 0.76 1433.81 1.00 1918 107 123 9 TRUE 0.15
non-small cell lung cancer KRAS_G12V ARID1A 55 152 Male -0.21 -1.10 0.58 1408.20 1.00 1362 51 148 4 TRUE 0.20
pancreatic cancer KRAS_G12V ARID1A 183 62 Female -0.28 -0.83 0.17 453.59 1.01 496 172 51 11 TRUE 0.55
pancreatic cancer KRAS_G12V ARID1A 208 65 Male -0.18 -0.62 0.32 129.92 1.03 560 191 48 17 TRUE 0.35
uterine cancer KRAS_G12V ARID1A 70 527 Female 0.76 0.31 1.26 1319.95 1.00 733 29 486 41 TRUE 2.60
cancer of unknown primary KRAS_G12V ARID1A 54 116 Sex:overall -0.44 -3.79 1.67 1303.76 1.00 675 45 107 9 TRUE 0.13
colorectal cancer KRAS_G12V ARID1A 205 315 Sex:overall -0.68 -1.36 -0.04 379.30 1.01 1875 189 299 16 TRUE 1.19
non-small cell lung cancer KRAS_G12V ARID1A 171 284 Sex:overall -0.03 -1.14 0.95 1545.26 1.00 3280 158 271 13 TRUE 0.02
pancreatic cancer KRAS_G12V ARID1A 391 127 Sex:overall -0.22 -0.76 0.35 325.80 1.01 1056 363 99 28 TRUE 0.35
uterine cancer KRAS_G12V ARID1A 70 527 Sex:overall 0.57 -4.18 4.61 1591.89 1.00 733 29 486 41 TRUE 0.11
colorectal cancer KRAS_G12V PIK3R1 102 44 Female -0.49 -1.51 0.35 1046.41 1.00 911 99 41 3 TRUE 0.50
colorectal cancer KRAS_G12V PIK3R1 102 72 Male -0.50 -1.41 0.30 888.93 1.00 1078 98 68 4 TRUE 0.58
non-small cell lung cancer KRAS_G12V PIK3R1 114 30 Female 0.05 -1.47 1.16 1145.61 1.00 2006 112 28 2 TRUE 0.03
non-small cell lung cancer KRAS_G12V PIK3R1 55 25 Male -0.01 -1.58 1.20 938.97 1.00 1472 54 24 1 TRUE 0.00
uterine cancer KRAS_G12V PIK3R1 60 268 Female -0.21 -0.86 0.44 1268.13 1.00 847 48 256 12 TRUE 0.27
colorectal cancer KRAS_G12V PIK3R1 204 116 Sex:overall -0.48 -1.55 0.48 1154.47 1.00 1989 197 109 7 TRUE 0.43
non-small cell lung cancer KRAS_G12V PIK3R1 169 55 Sex:overall 0.05 -1.56 1.36 1068.90 1.00 3478 166 52 3 TRUE 0.02
uterine cancer KRAS_G12V PIK3R1 60 268 Sex:overall -0.17 -4.60 3.98 1489.06 1.00 847 48 256 12 TRUE 0.03
colorectal cancer KRAS_G12V IKZF1 102 42 Female -2.57 -5.26 -0.79 659.15 1.00 911 101 41 1 TRUE 1.67
colorectal cancer KRAS_G12V IKZF1 102 44 Male -2.73 -5.55 -0.94 808.71 1.00 1089 102 44 0 TRUE 1.67
non-small cell lung cancer KRAS_G12V IKZF1 114 48 Female -1.79 -4.51 0.02 1074.25 1.00 1987 113 47 1 TRUE 0.87
non-small cell lung cancer KRAS_G12V IKZF1 55 34 Male -1.99 -5.23 0.03 1026.99 1.01 1462 55 34 0 TRUE 0.85
colorectal cancer KRAS_G12V IKZF1 204 86 Sex:overall -2.64 -5.38 -0.87 659.39 1.00 2000 203 85 1 TRUE 1.67
non-small cell lung cancer KRAS_G12V IKZF1 169 82 Sex:overall -1.85 -4.78 0.19 985.32 1.01 3449 168 81 1 TRUE 0.80
colorectal cancer KRAS_G12V TERT 102 40 Female -0.66 -1.76 0.30 762.51 1.01 914 99 37 3 TRUE 0.68
colorectal cancer KRAS_G12V TERT 103 58 Male -0.77 -1.88 0.12 592.86 1.00 1083 101 56 2 TRUE 0.83
non-small cell lung cancer KRAS_G12V TERT 114 87 Female -0.54 -1.69 0.40 1359.38 1.00 1953 111 84 3 TRUE 0.52
non-small cell lung cancer KRAS_G12V TERT 55 79 Male -0.53 -1.77 0.50 1557.70 1.00 1423 53 77 2 TRUE 0.43
uterine cancer KRAS_G12V TERT 58 65 Female -1.80 -4.55 0.08 1202.97 1.00 989 57 64 1 TRUE 0.89
colorectal cancer KRAS_G12V TERT 205 98 Sex:overall -0.71 -1.86 0.32 711.74 1.00 1997 200 93 5 TRUE 0.63
non-small cell lung cancer KRAS_G12V TERT 169 166 Sex:overall -0.55 -1.84 0.64 1510.14 1.00 3376 164 161 5 TRUE 0.39
uterine cancer KRAS_G12V TERT 58 65 Sex:overall -1.53 -6.04 3.02 1325.40 1.00 989 57 64 1 TRUE 0.31
colorectal cancer KRAS_G12V FAT1 102 97 Female -1.39 -2.45 -0.43 58.94 1.06 879 100 95 2 FALSE 2.12
colorectal cancer KRAS_G12V FAT1 102 130 Male -1.30 -2.30 -0.39 72.80 1.04 1056 98 126 4 FALSE 2.15
non-small cell lung cancer KRAS_G12V FAT1 114 155 Female -0.33 -1.07 0.35 1533.98 1.00 1898 107 148 7 FALSE 0.43
non-small cell lung cancer KRAS_G12V FAT1 55 150 Male -0.53 -1.54 0.26 1422.91 1.00 1367 52 147 3 FALSE 0.62
uterine cancer KRAS_G12V FAT1 59 183 Female -0.40 -1.34 0.45 1262.51 1.00 955 52 176 7 FALSE 0.44
colorectal cancer KRAS_G12V FAT1 204 227 Sex:overall -1.33 -2.42 -0.43 98.36 1.03 1935 198 221 6 FALSE 1.79
non-small cell lung cancer KRAS_G12V FAT1 169 305 Sex:overall -0.43 -1.51 0.51 1253.38 1.00 3265 159 295 10 FALSE 0.39
uterine cancer KRAS_G12V FAT1 59 183 Sex:overall -0.36 -5.13 4.07 1427.10 1.00 955 52 176 7 FALSE 0.07
colorectal cancer KRAS_G12V FGFR4 102 19 Female -2.15 -5.23 -0.31 941.47 1.00 932 102 19 0 TRUE 1.04
colorectal cancer KRAS_G12V FGFR4 102 34 Male -1.97 -4.78 -0.20 911.51 1.00 1101 101 33 1 TRUE 1.05
colorectal cancer KRAS_G12V FGFR4 204 53 Sex:overall -2.04 -4.96 -0.23 987.19 1.00 2033 203 52 1 TRUE 1.04
colorectal cancer KRAS_G12V CIC 102 58 Female -0.80 -1.86 0.03 891.65 1.00 905 100 56 2 TRUE 0.98
colorectal cancer KRAS_G12V CIC 102 79 Male -0.62 -1.47 0.21 965.67 1.00 1074 97 74 5 TRUE 0.81
non-small cell lung cancer KRAS_G12V CIC 114 43 Female -0.24 -1.84 0.92 998.64 1.00 1996 111 40 3 TRUE 0.14
non-small cell lung cancer KRAS_G12V CIC 55 49 Male -1.25 -5.18 0.44 1205.65 1.00 1455 55 49 0 TRUE 0.43
uterine cancer KRAS_G12V CIC 59 75 Female 0.38 -0.58 1.23 1101.14 1.00 999 53 69 6 TRUE 0.40
colorectal cancer KRAS_G12V CIC 204 137 Sex:overall -0.72 -1.75 0.14 1091.78 1.00 1979 197 130 7 TRUE 0.82
non-small cell lung cancer KRAS_G12V CIC 169 92 Sex:overall -0.67 -3.06 1.09 1474.34 1.00 3451 166 89 3 TRUE 0.28
uterine cancer KRAS_G12V CIC 59 75 Sex:overall 0.37 -4.07 4.61 1330.14 1.00 999 53 69 6 TRUE 0.07
colorectal cancer KRAS_G12V KDM6A 102 31 Female 0.20 -0.72 1.05 870.76 1.00 924 98 27 4 FALSE 0.18
colorectal cancer KRAS_G12V KDM6A 102 31 Male 0.14 -0.81 1.02 919.25 1.00 1105 99 28 3 FALSE 0.12
non-small cell lung cancer KRAS_G12V KDM6A 114 28 Female -0.64 -2.60 0.75 1009.55 1.00 2008 113 27 1 FALSE 0.35
non-small cell lung cancer KRAS_G12V KDM6A 55 33 Male -0.56 -2.44 0.97 1182.84 1.00 1465 54 32 1 FALSE 0.29
pancreatic cancer KRAS_G12V KDM6A 183 21 Female 0.24 -0.53 0.87 1156.23 1.00 529 177 15 6 FALSE 0.29
pancreatic cancer KRAS_G12V KDM6A 207 38 Male 0.37 -0.28 0.96 986.85 1.00 579 194 25 13 FALSE 0.62
uterine cancer KRAS_G12V KDM6A 58 54 Female -1.49 -4.23 0.26 1293.36 1.00 1005 57 53 1 FALSE 0.70
colorectal cancer KRAS_G12V KDM6A 204 62 Sex:overall 0.18 -0.83 1.14 844.74 1.00 2029 197 55 7 FALSE 0.14
non-small cell lung cancer KRAS_G12V KDM6A 169 61 Sex:overall -0.60 -2.66 0.92 1200.57 1.00 3473 167 59 2 FALSE 0.30
pancreatic cancer KRAS_G12V KDM6A 390 59 Sex:overall 0.30 -0.50 1.05 1217.19 1.00 1108 371 40 19 FALSE 0.34
uterine cancer KRAS_G12V KDM6A 58 54 Sex:overall -1.25 -5.82 3.81 1523.07 1.00 1005 57 53 1 FALSE 0.22
colorectal cancer KRAS_G12V NCOR1 102 54 Female -0.57 -1.48 0.27 818.04 1.00 903 99 51 3 FALSE 0.70
colorectal cancer KRAS_G12V NCOR1 105 81 Male -0.52 -1.34 0.26 589.77 1.00 1073 100 76 5 FALSE 0.65
non-small cell lung cancer KRAS_G12V NCOR1 114 53 Female -2.03 -4.96 -0.19 635.44 1.01 1988 113 52 1 FALSE 1.05
non-small cell lung cancer KRAS_G12V NCOR1 55 51 Male -2.36 -5.65 -0.27 806.07 1.01 1447 55 51 0 FALSE 0.93
uterine cancer KRAS_G12V NCOR1 58 90 Female -5.96 -14.67 -1.30 656.03 1.01 994 58 90 0 FALSE 0.88
colorectal cancer KRAS_G12V NCOR1 207 135 Sex:overall -0.55 -1.49 0.33 872.77 1.00 1976 199 127 8 FALSE 0.61
non-small cell lung cancer KRAS_G12V NCOR1 169 104 Sex:overall -2.16 -5.03 -0.18 680.67 1.00 3435 168 103 1 FALSE 1.04
uterine cancer KRAS_G12V NCOR1 58 90 Sex:overall -4.51 -11.37 2.30 839.08 1.00 994 58 90 0 FALSE 0.74
colorectal cancer KRAS_G12V POLE 102 59 Female -2.10 -4.58 -0.76 1176.36 1.00 899 102 59 0 TRUE 1.17
colorectal cancer KRAS_G12V POLE 102 82 Male -1.58 -2.93 -0.38 849.04 1.00 1071 99 79 3 TRUE 1.87
non-small cell lung cancer KRAS_G12V POLE 115 67 Female 0.67 -0.13 1.42 1309.62 1.00 1979 107 59 8 TRUE 1.08
non-small cell lung cancer KRAS_G12V POLE 55 69 Male 0.12 -1.30 1.05 1385.39 1.00 1431 53 67 2 TRUE 0.08
uterine cancer KRAS_G12V POLE 58 111 Female -2.31 -4.99 -0.49 649.57 1.00 983 57 110 1 TRUE 1.27
colorectal cancer KRAS_G12V POLE 204 141 Sex:overall -1.79 -3.47 -0.51 1122.90 1.00 1970 201 138 3 TRUE 1.59
non-small cell lung cancer KRAS_G12V POLE 170 136 Sex:overall 0.41 -1.10 1.54 1717.55 1.00 3410 160 126 10 TRUE 0.28
uterine cancer KRAS_G12V POLE 58 111 Sex:overall -1.97 -6.33 2.98 1016.31 1.00 983 57 110 1 TRUE 0.41
non-small cell lung cancer KRAS_G12V CUL3 115 34 Female 0.43 -0.88 1.56 1491.06 1.00 2007 111 30 4 FALSE 0.30
non-small cell lung cancer KRAS_G12V CUL3 55 43 Male -1.13 -5.41 0.74 1221.02 1.00 1455 55 43 0 FALSE 0.33
non-small cell lung cancer KRAS_G12V CUL3 170 77 Sex:overall -0.32 -3.15 1.66 1485.72 1.00 3462 166 73 4 FALSE 0.10
colorectal cancer KRAS_G12V ABL1 114 34 Female -0.61 -1.74 0.38 1172.58 1.00 1009 111 31 3 TRUE 0.62
colorectal cancer KRAS_G12V ABL1 113 39 Male -0.77 -2.17 0.27 1052.55 1.00 1219 112 38 1 TRUE 0.75
colorectal cancer KRAS_G12V ABL1 227 73 Sex:overall -0.69 -1.97 0.39 1164.31 1.00 2228 223 69 4 TRUE 0.66
colorectal cancer KRAS_G12V FOXP1 102 24 Female -0.83 -2.34 0.51 1324.08 1.00 927 100 22 2 FALSE 0.60
colorectal cancer KRAS_G12V FOXP1 102 46 Male -1.13 -2.75 0.14 989.42 1.00 1091 101 45 1 FALSE 0.92
colorectal cancer KRAS_G12V FOXP1 204 70 Sex:overall -0.98 -2.70 0.50 1326.11 1.00 2018 201 67 3 FALSE 0.62
colorectal cancer KRAS_G12V NOTCH2 95 30 Female -2.52 -5.72 -0.52 718.10 1.00 897 95 30 0 TRUE 1.20
colorectal cancer KRAS_G12V NOTCH2 99 43 Male -2.32 -5.13 -0.50 921.36 1.00 1065 98 42 1 TRUE 1.29
non-small cell lung cancer KRAS_G12V NOTCH2 114 62 Female 0.08 -1.05 1.05 761.58 1.00 1970 109 57 5 TRUE 0.05
non-small cell lung cancer KRAS_G12V NOTCH2 55 53 Male -1.00 -4.85 0.57 1106.20 1.00 1442 55 53 0 TRUE 0.33
uterine cancer KRAS_G12V NOTCH2 56 54 Female -5.84 -15.78 -0.92 1012.80 1.00 949 56 54 0 TRUE 0.84
colorectal cancer KRAS_G12V NOTCH2 194 73 Sex:overall -2.40 -5.37 -0.47 862.05 1.00 1962 193 72 1 TRUE 1.26
non-small cell lung cancer KRAS_G12V NOTCH2 169 115 Sex:overall -0.44 -3.05 0.97 1325.77 1.00 3412 164 110 5 TRUE 0.18
uterine cancer KRAS_G12V NOTCH2 56 54 Sex:overall -4.30 -11.82 2.39 1150.10 1.00 949 56 54 0 TRUE 0.64
non-small cell lung cancer KRAS_G12V DDR2 114 49 Female 0.40 -0.61 1.34 1394.09 1.00 1989 109 44 5 TRUE 0.37
non-small cell lung cancer KRAS_G12V DDR2 55 49 Male -0.07 -1.75 1.00 1172.54 1.00 1447 54 48 1 TRUE 0.04
uterine cancer KRAS_G12V DDR2 58 57 Female -6.00 -15.68 -0.90 1245.65 1.00 1009 58 57 0 TRUE 0.64
non-small cell lung cancer KRAS_G12V DDR2 169 98 Sex:overall 0.14 -1.50 1.32 1398.04 1.00 3436 163 92 6 TRUE 0.07
uterine cancer KRAS_G12V DDR2 58 57 Sex:overall -4.22 -11.50 3.25 1279.08 1.00 1009 58 57 0 TRUE 0.63
colorectal cancer KRAS_G12V TGFBR2 102 53 Female -0.90 -2.21 0.05 985.29 1.00 899 101 52 1 TRUE 0.90
colorectal cancer KRAS_G12V TGFBR2 103 61 Male -0.54 -1.49 0.39 1191.95 1.00 1078 98 56 5 TRUE 0.59
non-small cell lung cancer KRAS_G12V TGFBR2 114 35 Female -1.36 -5.78 0.57 1251.55 1.00 2002 114 35 0 TRUE 0.40
non-small cell lung cancer KRAS_G12V TGFBR2 55 21 Male -0.08 -2.12 1.70 102.92 1.03 1476 53 19 2 TRUE 0.03
colorectal cancer KRAS_G12V TGFBR2 205 114 Sex:overall -0.70 -1.90 0.41 1596.83 1.00 1977 199 108 6 TRUE 0.61
non-small cell lung cancer KRAS_G12V TGFBR2 169 56 Sex:overall -0.66 -3.36 1.47 791.11 1.01 3478 167 54 2 TRUE 0.22
colorectal cancer KRAS_G12V SMO 113 32 Female -0.28 -1.55 0.77 309.85 1.01 1012 109 28 4 TRUE 0.20
colorectal cancer KRAS_G12V SMO 113 39 Male -0.59 -2.00 0.48 719.83 1.00 1218 112 38 1 TRUE 0.45
non-small cell lung cancer KRAS_G12V SMO 118 39 Female -0.68 -2.43 0.88 482.73 1.00 2061 116 37 2 TRUE 0.38
non-small cell lung cancer KRAS_G12V SMO 58 36 Male -1.14 -3.67 0.79 715.11 1.00 1514 58 36 0 TRUE 0.46
uterine cancer KRAS_G12V SMO 66 52 Female -5.84 -15.95 -0.83 1239.29 1.00 1112 66 52 0 TRUE 0.73
colorectal cancer KRAS_G12V SMO 226 71 Sex:overall -0.44 -1.80 0.72 692.77 1.01 2230 221 66 5 TRUE 0.29
non-small cell lung cancer KRAS_G12V SMO 176 75 Sex:overall -0.92 -3.19 0.84 627.92 1.00 3575 174 73 2 TRUE 0.42
uterine cancer KRAS_G12V SMO 66 52 Sex:overall -4.12 -11.35 3.00 1388.35 1.00 1112 66 52 0 TRUE 0.59
colorectal cancer KRAS_G12V RPS6KA4 95 26 Female -2.30 -5.30 -0.39 512.28 1.00 899 95 26 0 FALSE 1.17
colorectal cancer KRAS_G12V RPS6KA4 99 37 Male -2.16 -4.99 -0.29 573.16 1.00 1067 98 36 1 FALSE 1.14
colorectal cancer KRAS_G12V RPS6KA4 194 63 Sex:overall -2.19 -4.99 -0.31 550.59 1.00 1966 193 62 1 FALSE 1.12
colorectal cancer KRAS_G12V KMT2A 102 69 Female -1.46 -2.90 -0.48 54.77 1.05 898 101 68 1 FALSE 1.63
colorectal cancer KRAS_G12V KMT2A 102 79 Male -1.31 -2.51 -0.38 77.37 1.04 1072 99 76 3 FALSE 1.63
non-small cell lung cancer KRAS_G12V KMT2A 114 64 Female 0.09 -0.86 1.03 1451.53 1.00 1978 110 60 4 FALSE 0.07
non-small cell lung cancer KRAS_G12V KMT2A 55 50 Male 0.07 -1.17 1.05 1390.19 1.00 1449 53 48 2 FALSE 0.05
uterine cancer KRAS_G12V KMT2A 58 109 Female -1.28 -3.10 0.12 1003.42 1.00 987 56 107 2 FALSE 0.97
colorectal cancer KRAS_G12V KMT2A 204 148 Sex:overall -1.38 -2.76 -0.39 69.38 1.04 1970 200 144 4 FALSE 1.48
non-small cell lung cancer KRAS_G12V KMT2A 169 114 Sex:overall 0.09 -1.12 1.21 1361.55 1.00 3427 163 108 6 FALSE 0.06
uterine cancer KRAS_G12V KMT2A 58 109 Sex:overall -1.02 -5.23 3.58 1447.33 1.00 987 56 107 2 FALSE 0.20
colorectal cancer KRAS_G12V JAK3 113 33 Female -2.50 -5.54 -0.62 358.68 1.01 1009 113 33 0 TRUE 1.24
colorectal cancer KRAS_G12V JAK3 113 30 Male -2.20 -4.86 -0.30 344.62 1.00 1223 112 29 1 TRUE 1.20
non-small cell lung cancer KRAS_G12V JAK3 119 50 Female 0.58 -0.49 1.46 1260.65 1.00 2052 113 44 6 TRUE 0.64
non-small cell lung cancer KRAS_G12V JAK3 58 33 Male -0.59 -4.55 1.05 1111.74 1.00 1518 58 33 0 TRUE 0.14
colorectal cancer KRAS_G12V JAK3 226 63 Sex:overall -2.34 -5.00 -0.40 353.20 1.01 2232 225 62 1 TRUE 1.24
non-small cell lung cancer KRAS_G12V JAK3 177 83 Sex:overall 0.02 -2.73 1.60 1226.14 1.00 3570 171 77 6 TRUE 0.01
non-small cell lung cancer KRAS_G12V PAK7 114 71 Female 0.70 -0.02 1.42 1081.68 1.00 1962 106 63 8 FALSE 1.31
non-small cell lung cancer KRAS_G12V PAK7 55 62 Male 0.51 -0.56 1.31 1144.80 1.00 1437 52 59 3 FALSE 0.57
non-small cell lung cancer KRAS_G12V PAK7 169 133 Sex:overall 0.61 -0.48 1.58 1265.45 1.00 3399 158 122 11 FALSE 0.56
non-small cell lung cancer KRAS_G12V STAG2 115 75 Female 0.23 -0.78 1.06 1611.54 1.00 1967 109 69 6 TRUE 0.21
non-small cell lung cancer KRAS_G12V STAG2 55 27 Male -0.88 -4.80 0.86 1230.74 1.00 1470 55 27 0 TRUE 0.24
uterine cancer KRAS_G12V STAG2 58 85 Female -1.96 -4.63 -0.14 1099.99 1.00 997 57 84 1 TRUE 1.08
non-small cell lung cancer KRAS_G12V STAG2 170 102 Sex:overall -0.30 -3.17 1.50 1326.43 1.00 3437 164 96 6 TRUE 0.10
uterine cancer KRAS_G12V STAG2 58 85 Sex:overall -1.65 -6.10 3.26 1458.94 1.00 997 57 84 1 TRUE 0.34
colorectal cancer KRAS_G12V BRCA2 102 75 Female -1.23 -2.21 -0.34 1363.85 1.00 890 99 72 3 TRUE 1.94
colorectal cancer KRAS_G12V BRCA2 102 115 Male -1.27 -2.23 -0.42 856.90 1.00 1069 99 112 3 TRUE 2.17
non-small cell lung cancer KRAS_G12V BRCA2 115 72 Female -0.23 -1.35 0.61 940.89 1.00 1973 111 68 4 TRUE 0.19
non-small cell lung cancer KRAS_G12V BRCA2 55 63 Male -0.49 -1.98 0.54 708.65 1.00 1436 54 62 1 TRUE 0.33
uterine cancer KRAS_G12V BRCA2 58 134 Female -2.44 -5.29 -0.63 1498.11 1.00 974 57 133 1 TRUE 1.42
colorectal cancer KRAS_G12V BRCA2 204 190 Sex:overall -1.24 -2.26 -0.27 1056.92 1.00 1959 198 184 6 TRUE 1.72
non-small cell lung cancer KRAS_G12V BRCA2 170 135 Sex:overall -0.36 -1.84 0.78 1080.60 1.00 3409 165 130 5 TRUE 0.22
uterine cancer KRAS_G12V BRCA2 58 134 Sex:overall -1.93 -6.49 3.30 1473.57 1.00 974 57 133 1 TRUE 0.39
colorectal cancer KRAS_G12V NOTCH3 102 88 Female -0.98 -1.87 -0.23 682.52 1.00 879 99 85 3 TRUE 1.73
colorectal cancer KRAS_G12V NOTCH3 103 112 Male -0.92 -1.71 -0.19 750.26 1.00 1050 98 107 5 TRUE 1.69
non-small cell lung cancer KRAS_G12V NOTCH3 114 64 Female 0.32 -0.64 1.18 1231.64 1.00 1979 108 58 6 TRUE 0.32
non-small cell lung cancer KRAS_G12V NOTCH3 55 64 Male -0.27 -1.83 0.83 1483.51 1.00 1437 54 63 1 TRUE 0.16
uterine cancer KRAS_G12V NOTCH3 58 91 Female -1.19 -2.95 0.10 1377.34 1.00 983 56 89 2 TRUE 0.87
colorectal cancer KRAS_G12V NOTCH3 205 200 Sex:overall -0.94 -1.84 -0.17 779.76 1.00 1929 197 192 8 TRUE 1.46
non-small cell lung cancer KRAS_G12V NOTCH3 169 128 Sex:overall 0.03 -1.57 1.33 1452.16 1.00 3416 162 121 7 TRUE 0.02
uterine cancer KRAS_G12V NOTCH3 58 91 Sex:overall -0.95 -4.82 3.96 1224.61 1.00 983 56 89 2 TRUE 0.19
colorectal cancer KRAS_G12V NOTCH4 95 45 Female -1.37 -2.79 -0.19 1007.72 1.00 882 93 43 2 TRUE 1.40
colorectal cancer KRAS_G12V NOTCH4 99 77 Male -1.57 -3.06 -0.46 627.02 1.00 1039 98 76 1 TRUE 1.73
non-small cell lung cancer KRAS_G12V NOTCH4 114 82 Female 0.40 -0.34 1.12 345.19 1.01 1950 106 74 8 TRUE 0.52
non-small cell lung cancer KRAS_G12V NOTCH4 55 57 Male -0.08 -1.68 0.92 1296.52 1.00 1437 54 56 1 TRUE 0.05
uterine cancer KRAS_G12V NOTCH4 57 65 Female -0.83 -2.76 0.51 1398.71 1.00 945 55 63 2 TRUE 0.50
colorectal cancer KRAS_G12V NOTCH4 194 122 Sex:overall -1.46 -3.08 -0.16 1041.44 1.00 1921 191 119 3 TRUE 1.29
non-small cell lung cancer KRAS_G12V NOTCH4 169 139 Sex:overall 0.17 -1.39 1.31 1346.13 1.00 3387 160 130 9 TRUE 0.09
uterine cancer KRAS_G12V NOTCH4 57 65 Sex:overall -0.72 -5.04 4.22 1562.65 1.00 945 55 63 2 TRUE 0.13
colorectal cancer KRAS_G12V FGFR3 113 25 Female -1.34 -3.13 0.06 1320.20 1.00 1015 112 24 1 TRUE 1.00
colorectal cancer KRAS_G12V FGFR3 113 35 Male -1.34 -3.10 0.07 1466.48 1.00 1221 112 34 1 TRUE 1.02
colorectal cancer KRAS_G12V FGFR3 226 60 Sex:overall -1.34 -3.12 0.14 1175.72 1.00 2236 224 58 2 TRUE 0.99
non-small cell lung cancer KRAS_G12V MAP3K13 115 30 Female 0.99 -0.05 1.84 1539.38 1.00 1996 110 25 5 FALSE 1.36
non-small cell lung cancer KRAS_G12V MAP3K13 55 22 Male 0.68 -0.90 1.79 1492.42 1.00 1469 54 21 1 FALSE 0.52
non-small cell lung cancer KRAS_G12V MAP3K13 170 52 Sex:overall 0.84 -0.51 2.01 1433.69 1.00 3465 164 46 6 FALSE 0.70
colorectal cancer KRAS_G12V IGF1R 102 31 Female -1.15 -2.70 0.01 897.10 1.00 921 101 30 1 TRUE 1.00
colorectal cancer KRAS_G12V IGF1R 102 49 Male -1.09 -2.46 0.02 867.78 1.00 1092 100 47 2 TRUE 1.05
non-small cell lung cancer KRAS_G12V IGF1R 114 31 Female -4.74 -11.65 -0.62 663.74 1.01 2003 114 31 0 TRUE 1.05
non-small cell lung cancer KRAS_G12V IGF1R 55 23 Male -4.70 -11.14 -0.40 715.51 1.01 1472 55 23 0 TRUE 1.03
colorectal cancer KRAS_G12V IGF1R 204 80 Sex:overall -1.12 -2.59 0.10 910.46 1.00 2013 201 77 3 TRUE 0.94
non-small cell lung cancer KRAS_G12V IGF1R 169 54 Sex:overall -4.62 -11.12 -0.48 767.05 1.01 3475 169 54 0 TRUE 1.01
non-small cell lung cancer KRAS_G12V KEAP1 114 248 Female 0.16 -0.38 0.67 1494.23 1.00 1809 98 232 16 FALSE 0.25
non-small cell lung cancer KRAS_G12V KEAP1 55 290 Male -0.12 -0.80 0.51 1627.63 1.00 1229 46 281 9 FALSE 0.14
non-small cell lung cancer KRAS_G12V KEAP1 169 538 Sex:overall 0.03 -1.08 1.05 1530.98 1.00 3038 144 513 25 FALSE 0.02
colorectal cancer KRAS_G12V KDM5C 102 41 Female -1.40 -3.24 -0.03 674.98 1.00 920 100 39 2 FALSE 1.06
colorectal cancer KRAS_G12V KDM5C 102 28 Male -1.94 -4.82 -0.23 918.12 1.00 1105 102 28 0 FALSE 0.91
non-small cell lung cancer KRAS_G12V KDM5C 114 71 Female 0.65 -0.23 1.38 1060.48 1.00 1974 106 63 8 FALSE 0.95
non-small cell lung cancer KRAS_G12V KDM5C 55 35 Male -0.63 -4.49 0.96 718.62 1.00 1461 55 35 0 FALSE 0.16
uterine cancer KRAS_G12V KDM5C 59 67 Female -0.31 -1.72 0.83 1154.88 1.00 1005 56 64 3 FALSE 0.20
colorectal cancer KRAS_G12V KDM5C 204 69 Sex:overall -1.63 -3.99 0.05 890.49 1.00 2025 202 67 2 FALSE 0.93
non-small cell lung cancer KRAS_G12V KDM5C 169 106 Sex:overall 0.04 -2.64 1.47 1086.02 1.00 3435 161 98 8 FALSE 0.01
uterine cancer KRAS_G12V KDM5C 59 67 Sex:overall -0.34 -4.60 3.97 1501.64 1.00 1005 56 64 3 FALSE 0.06
non-small cell lung cancer KRAS_G12V CDKN2A 119 139 Female 0.02 -0.67 0.64 1548.46 1.00 1975 111 131 8 TRUE 0.02
non-small cell lung cancer KRAS_G12V CDKN2A 58 137 Male -0.02 -0.83 0.71 1501.44 1.00 1424 53 132 5 TRUE 0.02
pancreatic cancer KRAS_G12V CDKN2A 190 134 Female 0.34 0.02 0.66 958.12 1.00 485 148 92 42 TRUE 1.46
pancreatic cancer KRAS_G12V CDKN2A 215 160 Male 0.32 0.00 0.62 998.24 1.00 515 167 112 48 TRUE 1.44
non-small cell lung cancer KRAS_G12V CDKN2A 177 276 Sex:overall -0.02 -1.03 0.93 1379.28 1.00 3399 164 263 13 TRUE 0.01
pancreatic cancer KRAS_G12V CDKN2A 405 294 Sex:overall 0.33 -0.04 0.73 1261.73 1.00 1000 315 204 90 TRUE 0.97
colorectal cancer KRAS_G12V EPHB1 102 32 Female -1.45 -4.25 -0.17 240.24 1.00 917 102 32 0 FALSE 0.78
colorectal cancer KRAS_G12V EPHB1 102 50 Male -0.95 -2.41 0.17 337.14 1.01 1087 99 47 3 FALSE 0.83
non-small cell lung cancer KRAS_G12V EPHB1 114 81 Female -0.40 -1.49 0.49 1377.32 1.00 1966 110 77 4 FALSE 0.37
non-small cell lung cancer KRAS_G12V EPHB1 55 77 Male -0.73 -2.25 0.31 1367.62 1.00 1423 54 76 1 FALSE 0.58
colorectal cancer KRAS_G12V EPHB1 204 82 Sex:overall -1.17 -3.14 0.14 325.07 1.00 2004 201 79 3 FALSE 0.75
non-small cell lung cancer KRAS_G12V EPHB1 169 158 Sex:overall -0.54 -1.93 0.66 1548.22 1.00 3389 164 153 5 FALSE 0.38
colorectal cancer KRAS_G12V IRS2 102 29 Female -1.73 -4.65 -0.16 1244.28 1.00 923 102 29 0 FALSE 0.60
colorectal cancer KRAS_G12V IRS2 103 58 Male -1.03 -2.50 0.12 1340.67 1.00 1081 100 55 3 FALSE 0.94
non-small cell lung cancer KRAS_G12V IRS2 114 42 Female 0.29 -0.94 1.23 1247.91 1.00 1997 110 38 4 FALSE 0.23
non-small cell lung cancer KRAS_G12V IRS2 55 42 Male -0.06 -1.71 1.10 1479.31 1.00 1455 54 41 1 FALSE 0.03
uterine cancer KRAS_G12V IRS2 59 74 Female -0.09 -1.31 0.88 1225.62 1.00 994 55 70 4 FALSE 0.06
colorectal cancer KRAS_G12V IRS2 205 87 Sex:overall -1.31 -3.43 0.22 1468.36 1.00 2004 202 84 3 FALSE 0.76
non-small cell lung cancer KRAS_G12V IRS2 169 84 Sex:overall 0.13 -1.38 1.37 1603.32 1.00 3452 164 79 5 FALSE 0.07
uterine cancer KRAS_G12V IRS2 59 74 Sex:overall -0.14 -4.69 4.70 1361.00 1.00 994 55 70 4 FALSE 0.02
colorectal cancer KRAS_G12V FANCA 102 31 Female -0.56 -1.71 0.45 912.35 1.01 921 100 29 2 TRUE 0.50
colorectal cancer KRAS_G12V FANCA 102 34 Male -0.55 -1.75 0.45 927.82 1.01 1104 100 32 2 TRUE 0.48
non-small cell lung cancer KRAS_G12V FANCA 114 39 Female 0.02 -1.71 1.12 198.01 1.01 1997 112 37 2 TRUE 0.01
non-small cell lung cancer KRAS_G12V FANCA 55 30 Male 0.17 -1.97 1.39 182.53 1.01 1469 53 28 2 TRUE 0.09
colorectal cancer KRAS_G12V FANCA 204 65 Sex:overall -0.56 -1.81 0.53 841.84 1.01 2025 200 61 4 TRUE 0.45
non-small cell lung cancer KRAS_G12V FANCA 169 69 Sex:overall 0.10 -1.96 1.45 237.42 1.00 3466 165 65 4 TRUE 0.05
non-small cell lung cancer KRAS_G12V IL7R 114 51 Female -0.68 -2.36 0.53 1024.86 1.00 1987 113 50 1 FALSE 0.44
non-small cell lung cancer KRAS_G12V IL7R 55 40 Male -0.31 -1.91 1.11 1430.43 1.00 1462 53 38 2 FALSE 0.17
non-small cell lung cancer KRAS_G12V IL7R 169 91 Sex:overall -0.48 -2.16 1.02 1249.26 1.00 3449 166 88 3 FALSE 0.25
uterine cancer KRAS_G12V PPP2R1A 58 159 Female -0.07 -0.95 0.69 1313.19 1.00 913 50 151 8 FALSE 0.07
uterine cancer KRAS_G12V PPP2R1A 58 159 Sex:overall -0.05 -4.52 4.29 1110.32 1.00 913 50 151 8 FALSE 0.01
colorectal cancer KRAS_G12V PIK3CB 95 24 Female -2.11 -4.90 -0.17 1255.47 1.00 903 94 23 1 FALSE 1.11
colorectal cancer KRAS_G12V PIK3CB 99 44 Male -2.52 -5.68 -0.61 1307.93 1.00 1070 99 44 0 FALSE 1.17
colorectal cancer KRAS_G12V PIK3CB 194 68 Sex:overall -2.29 -5.00 -0.21 1230.03 1.00 1973 193 67 1 FALSE 1.16
colorectal cancer KRAS_G12V ERBB3 102 52 Female -0.96 -2.44 0.00 934.15 1.01 905 101 51 1 TRUE 0.87
colorectal cancer KRAS_G12V ERBB3 102 70 Male -0.62 -1.58 0.30 1177.16 1.00 1073 97 65 5 TRUE 0.71
uterine cancer KRAS_G12V ERBB3 58 80 Female -0.50 -1.91 0.62 1528.47 1.00 982 55 77 3 TRUE 0.35
colorectal cancer KRAS_G12V ERBB3 204 122 Sex:overall -0.77 -1.97 0.25 1265.59 1.00 1978 198 116 6 TRUE 0.72
uterine cancer KRAS_G12V ERBB3 58 80 Sex:overall -0.44 -4.54 4.37 1651.17 1.00 982 55 77 3 TRUE 0.08
colorectal cancer KRAS_G12V SMAD4 114 170 Female 0.30 -0.21 0.68 520.09 1.00 901 96 152 18 TRUE 0.71
colorectal cancer KRAS_G12V SMAD4 116 190 Male 0.44 0.02 0.85 1339.23 1.00 1100 91 165 25 TRUE 1.49
non-small cell lung cancer KRAS_G12V SMAD4 118 74 Female -0.41 -1.72 0.56 1424.85 1.00 2027 116 72 2 TRUE 0.32
non-small cell lung cancer KRAS_G12V SMAD4 58 42 Male 0.10 -1.20 1.27 1347.17 1.00 1511 55 39 3 TRUE 0.06
pancreatic cancer KRAS_G12V SMAD4 187 136 Female 0.03 -0.34 0.36 1143.43 1.00 468 156 105 31 TRUE 0.06
pancreatic cancer KRAS_G12V SMAD4 214 139 Male 0.16 -0.18 0.55 882.39 1.00 528 171 96 43 TRUE 0.42
colorectal cancer KRAS_G12V SMAD4 230 360 Sex:overall 0.36 -0.25 0.82 1309.60 1.00 2001 187 317 43 TRUE 0.62
non-small cell lung cancer KRAS_G12V SMAD4 176 116 Sex:overall -0.14 -1.62 1.26 1391.22 1.00 3538 171 111 5 TRUE 0.07
pancreatic cancer KRAS_G12V SMAD4 401 275 Sex:overall 0.10 -0.41 0.55 1264.05 1.00 996 327 201 74 TRUE 0.16
colorectal cancer KRAS_G12V ATM 115 100 Female 0.18 -0.46 0.82 1408.50 1.00 968 101 86 14 TRUE 0.24
colorectal cancer KRAS_G12V ATM 114 131 Male -0.50 -1.48 0.23 1033.21 1.00 1161 109 126 5 TRUE 0.62
non-small cell lung cancer KRAS_G12V ATM 118 174 Female 0.52 -0.03 1.01 870.68 1.00 1958 104 160 14 TRUE 1.38
non-small cell lung cancer KRAS_G12V ATM 60 114 Male 0.57 -0.03 1.19 583.85 1.01 1452 52 106 8 TRUE 1.26
uterine cancer KRAS_G12V ATM 67 166 Female -0.32 -1.19 0.44 1198.34 1.00 1066 60 159 7 TRUE 0.36
colorectal cancer KRAS_G12V ATM 229 231 Sex:overall -0.15 -1.23 0.86 1531.24 1.00 2129 210 212 19 TRUE 0.11
non-small cell lung cancer KRAS_G12V ATM 178 288 Sex:overall 0.55 -0.20 1.27 1127.98 1.00 3410 156 266 22 TRUE 0.85
uterine cancer KRAS_G12V ATM 67 166 Sex:overall -0.30 -4.99 4.09 1543.62 1.00 1066 60 159 7 TRUE 0.05
colorectal cancer KRAS_G12V RB1 113 23 Female -0.52 -1.87 0.62 1174.13 1.00 1021 111 21 2 TRUE 0.39
colorectal cancer KRAS_G12V RB1 113 45 Male -0.63 -1.90 0.41 1038.91 1.00 1218 111 43 2 TRUE 0.54
non-small cell lung cancer KRAS_G12V RB1 118 107 Female -1.01 -2.21 0.02 1541.20 1.00 1996 115 104 3 TRUE 1.13
non-small cell lung cancer KRAS_G12V RB1 58 116 Male -1.29 -2.92 -0.13 1193.46 1.00 1436 57 115 1 TRUE 1.16
uterine cancer KRAS_G12V RB1 67 94 Female -1.23 -2.90 0.08 1199.00 1.00 1091 65 92 2 TRUE 0.94
colorectal cancer KRAS_G12V RB1 226 68 Sex:overall -0.57 -1.99 0.67 1075.20 1.00 2239 222 64 4 TRUE 0.38
non-small cell lung cancer KRAS_G12V RB1 176 223 Sex:overall -1.14 -2.66 0.10 1075.01 1.00 3432 172 219 4 TRUE 0.91
uterine cancer KRAS_G12V RB1 67 94 Sex:overall -1.09 -5.34 3.80 1125.98 1.00 1091 65 92 2 TRUE 0.22
cancer of unknown primary KRAS_G12V KMT2D 30 63 Female -0.32 -1.39 0.74 1051.38 1.00 348 25 58 5 FALSE 0.25
cancer of unknown primary KRAS_G12V KMT2D 21 62 Male -1.48 -5.56 0.15 767.84 1.00 321 21 62 0 FALSE 0.47
colorectal cancer KRAS_G12V KMT2D 102 187 Female -1.11 -1.85 -0.40 1157.25 1.00 848 93 178 9 FALSE 2.55
colorectal cancer KRAS_G12V KMT2D 102 201 Male -1.62 -3.00 -0.75 808.63 1.00 1007 100 199 2 FALSE 2.56
non-small cell lung cancer KRAS_G12V KMT2D 114 136 Female 0.31 -0.38 0.92 1412.90 1.00 1920 103 125 11 FALSE 0.44
non-small cell lung cancer KRAS_G12V KMT2D 55 192 Male -1.01 -2.41 0.04 1312.84 1.00 1340 53 190 2 FALSE 0.96
pancreatic cancer KRAS_G12V KMT2D 184 26 Female 0.31 -0.64 1.22 1071.49 1.00 528 174 16 10 FALSE 0.29
pancreatic cancer KRAS_G12V KMT2D 207 40 Male -1.13 -2.42 -0.13 859.36 1.00 573 204 37 3 FALSE 1.27
uterine cancer KRAS_G12V KMT2D 58 264 Female -0.51 -1.25 0.16 1304.54 1.00 887 49 255 9 FALSE 0.77
cancer of unknown primary KRAS_G12V KMT2D 51 125 Sex:overall -0.88 -3.22 0.48 1143.05 1.00 669 46 120 5 FALSE 0.44
colorectal cancer KRAS_G12V KMT2D 204 388 Sex:overall -1.35 -2.53 -0.41 1497.10 1.00 1855 193 377 11 FALSE 1.89
non-small cell lung cancer KRAS_G12V KMT2D 169 328 Sex:overall -0.34 -2.09 1.42 1399.30 1.00 3260 156 315 13 FALSE 0.15
pancreatic cancer KRAS_G12V KMT2D 391 66 Sex:overall -0.39 -2.23 1.45 1401.31 1.00 1101 378 53 13 FALSE 0.17
uterine cancer KRAS_G12V KMT2D 58 264 Sex:overall -0.42 -4.96 4.10 1349.31 1.00 887 49 255 9 FALSE 0.08
colorectal cancer KRAS_G12V TSC2 102 62 Female -1.34 -2.77 -0.08 1343.87 1.00 902 99 59 3 TRUE 1.35
colorectal cancer KRAS_G12V TSC2 102 53 Male -1.93 -4.58 -0.48 907.47 1.00 1086 102 53 0 TRUE 1.13
non-small cell lung cancer KRAS_G12V TSC2 114 46 Female 0.36 -0.76 1.30 1361.27 1.00 1994 110 42 4 TRUE 0.31
non-small cell lung cancer KRAS_G12V TSC2 55 26 Male 0.19 -1.29 1.38 1134.21 1.00 1471 54 25 1 TRUE 0.11
uterine cancer KRAS_G12V TSC2 58 74 Female -0.93 -2.66 0.40 1277.69 1.00 997 56 72 2 TRUE 0.61
colorectal cancer KRAS_G12V TSC2 204 115 Sex:overall -1.61 -3.64 -0.15 1250.17 1.00 1988 201 112 3 TRUE 1.15
non-small cell lung cancer KRAS_G12V TSC2 169 72 Sex:overall 0.28 -1.11 1.46 1445.71 1.00 3465 164 67 5 TRUE 0.16
uterine cancer KRAS_G12V TSC2 58 74 Sex:overall -0.66 -4.70 3.84 1477.93 1.00 997 56 72 2 TRUE 0.13
colorectal cancer KRAS_G12V APC 156 1110 Female 0.25 -0.11 0.62 1492.53 1.00 390 34 988 122 TRUE 0.76
colorectal cancer KRAS_G12V APC 155 1428 Male 0.00 -0.34 0.32 1291.05 1.00 426 41 1314 114 TRUE 0.00
non-small cell lung cancer KRAS_G12V APC 118 85 Female -0.72 -1.94 0.27 1449.17 1.00 2015 115 82 3 TRUE 0.69
non-small cell lung cancer KRAS_G12V APC 58 72 Male -0.87 -2.36 0.27 1425.72 1.00 1486 57 71 1 TRUE 0.68
uterine cancer KRAS_G12V APC 66 127 Female -1.52 -3.18 -0.20 903.01 1.00 1094 64 125 2 TRUE 1.35
colorectal cancer KRAS_G12V APC 311 2538 Sex:overall 0.12 -0.47 0.72 1403.72 1.00 816 75 2302 236 TRUE 0.16
non-small cell lung cancer KRAS_G12V APC 176 157 Sex:overall -0.78 -2.29 0.37 1399.85 1.00 3501 172 153 4 TRUE 0.62
uterine cancer KRAS_G12V APC 66 127 Sex:overall -1.36 -5.19 2.89 1294.95 1.00 1094 64 125 2 TRUE 0.32
colorectal cancer KRAS_G12V ERBB2 113 38 Female -0.87 -2.13 0.27 977.35 1.00 1006 110 35 3 TRUE 0.80
colorectal cancer KRAS_G12V ERBB2 113 66 Male -1.29 -2.87 -0.17 1186.05 1.00 1192 112 65 1 TRUE 1.23
non-small cell lung cancer KRAS_G12V ERBB2 118 76 Female -2.31 -4.77 -0.44 920.43 1.00 2024 117 75 1 TRUE 1.40
non-small cell lung cancer KRAS_G12V ERBB2 58 53 Male -2.45 -5.48 -0.52 920.89 1.00 1498 58 53 0 TRUE 1.32
uterine cancer KRAS_G12V ERBB2 66 58 Female -5.88 -15.63 -1.07 1288.52 1.00 1106 66 58 0 TRUE 0.83
colorectal cancer KRAS_G12V ERBB2 226 104 Sex:overall -1.07 -2.50 0.22 1194.51 1.00 2198 222 100 4 TRUE 0.88
non-small cell lung cancer KRAS_G12V ERBB2 176 129 Sex:overall -2.34 -4.94 -0.42 906.82 1.00 3522 175 128 1 TRUE 1.30
uterine cancer KRAS_G12V ERBB2 66 58 Sex:overall -4.32 -11.24 2.05 1114.86 1.00 1106 66 58 0 TRUE 0.69
colorectal cancer KRAS_G12V JAK1 102 29 Female -1.46 -3.26 -0.10 652.66 1.00 925 101 28 1 TRUE 1.15
colorectal cancer KRAS_G12V JAK1 102 46 Male -1.49 -3.35 -0.21 605.72 1.00 1096 101 45 1 TRUE 1.17
non-small cell lung cancer KRAS_G12V JAK1 114 19 Female -0.43 -2.48 1.17 1262.83 1.00 2017 113 18 1 TRUE 0.19
non-small cell lung cancer KRAS_G12V JAK1 55 33 Male -0.42 -2.53 1.20 1232.28 1.00 1464 54 32 1 TRUE 0.19
uterine cancer KRAS_G12V JAK1 59 145 Female -0.14 -1.08 0.60 810.09 1.00 954 52 138 7 TRUE 0.13
colorectal cancer KRAS_G12V JAK1 204 75 Sex:overall -1.46 -3.24 -0.11 603.12 1.00 2021 202 73 2 TRUE 1.11
non-small cell lung cancer KRAS_G12V JAK1 169 52 Sex:overall -0.43 -2.75 1.50 1360.42 1.00 3481 167 50 2 TRUE 0.16
uterine cancer KRAS_G12V JAK1 59 145 Sex:overall -0.15 -4.55 4.49 1461.87 1.00 954 52 138 7 TRUE 0.02
uterine cancer KRAS_G12V CCND1 58 69 Female 0.54 -0.41 1.36 1462.20 1.00 988 52 63 6 TRUE 0.62
uterine cancer KRAS_G12V CCND1 58 69 Sex:overall 0.48 -4.00 4.85 1500.32 1.00 988 52 63 6 TRUE 0.09
colorectal cancer KRAS_G12V ARID2 103 54 Female -0.57 -1.56 0.29 1029.61 1.00 902 99 50 4 FALSE 0.64
colorectal cancer KRAS_G12V ARID2 102 56 Male -0.69 -1.79 0.17 1135.87 1.00 1087 100 54 2 FALSE 0.76
non-small cell lung cancer KRAS_G12V ARID2 114 88 Female -0.94 -2.23 0.09 1208.35 1.00 1949 112 86 2 FALSE 0.92
non-small cell lung cancer KRAS_G12V ARID2 55 94 Male -0.84 -2.12 0.27 1430.55 1.00 1416 53 92 2 FALSE 0.76
uterine cancer KRAS_G12V ARID2 58 71 Female -1.84 -4.54 -0.03 1357.71 1.00 1001 57 70 1 FALSE 0.91
colorectal cancer KRAS_G12V ARID2 205 110 Sex:overall -0.64 -1.75 0.27 898.08 1.00 1989 199 104 6 FALSE 0.67
non-small cell lung cancer KRAS_G12V ARID2 169 182 Sex:overall -0.85 -2.23 0.37 1112.95 1.00 3365 165 178 4 FALSE 0.65
uterine cancer KRAS_G12V ARID2 58 71 Sex:overall -1.53 -5.77 3.29 1343.21 1.00 1001 57 70 1 FALSE 0.31
colorectal cancer KRAS_G12V SOX17 95 52 Female -0.98 -2.25 0.05 1042.31 1.00 875 93 50 2 FALSE 1.03
colorectal cancer KRAS_G12V SOX17 99 46 Male -0.95 -2.20 0.15 895.47 1.00 1063 97 44 2 FALSE 0.95
non-small cell lung cancer KRAS_G12V SOX17 114 34 Female 0.29 -0.91 1.30 1437.86 1.00 1992 111 31 3 FALSE 0.21
non-small cell lung cancer KRAS_G12V SOX17 55 27 Male 0.15 -1.39 1.34 1308.03 1.00 1464 54 26 1 FALSE 0.08
uterine cancer KRAS_G12V SOX17 56 52 Female 0.29 -0.92 1.32 1567.47 1.00 949 52 48 4 FALSE 0.21
colorectal cancer KRAS_G12V SOX17 194 98 Sex:overall -0.96 -2.34 0.17 1196.73 1.00 1938 190 94 4 FALSE 0.89
non-small cell lung cancer KRAS_G12V SOX17 169 61 Sex:overall 0.20 -1.34 1.45 1394.65 1.00 3456 165 57 4 FALSE 0.11
uterine cancer KRAS_G12V SOX17 56 52 Sex:overall 0.18 -4.46 4.20 1421.99 1.00 949 52 48 4 FALSE 0.03
colorectal cancer KRAS_G12V MTOR 102 75 Female -0.14 -0.93 0.57 1314.54 1.00 893 95 68 7 TRUE 0.15
colorectal cancer KRAS_G12V MTOR 102 65 Male -0.26 -1.09 0.44 1278.48 1.00 1079 98 61 4 TRUE 0.29
non-small cell lung cancer KRAS_G12V MTOR 114 64 Female -0.22 -1.36 0.82 1497.36 1.00 1974 110 60 4 TRUE 0.16
non-small cell lung cancer KRAS_G12V MTOR 55 51 Male -1.01 -4.42 0.50 1087.56 1.00 1446 55 51 0 TRUE 0.37
uterine cancer KRAS_G12V MTOR 59 90 Female -0.60 -1.99 0.41 256.70 1.00 982 56 87 3 TRUE 0.47
colorectal cancer KRAS_G12V MTOR 204 140 Sex:overall -0.20 -1.15 0.64 1370.53 1.00 1972 193 129 11 TRUE 0.18
non-small cell lung cancer KRAS_G12V MTOR 169 115 Sex:overall -0.60 -2.87 0.92 1330.07 1.00 3420 165 111 4 TRUE 0.28
uterine cancer KRAS_G12V MTOR 59 90 Sex:overall -0.52 -4.65 3.66 1260.70 1.00 982 56 87 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V RFWD2 114 30 Female -4.92 -11.69 -0.47 846.97 1.00 1991 114 30 0 FALSE 1.00
non-small cell lung cancer KRAS_G12V RFWD2 55 27 Male -4.87 -11.79 -0.38 804.08 1.00 1463 55 27 0 FALSE 0.98
non-small cell lung cancer KRAS_G12V RFWD2 169 57 Sex:overall -4.81 -11.26 -0.41 803.58 1.00 3454 169 57 0 FALSE 0.98
colorectal cancer KRAS_G12V IRS1 95 43 Female -0.64 -1.83 0.26 997.52 1.00 886 92 40 3 FALSE 0.65
colorectal cancer KRAS_G12V IRS1 99 54 Male -0.71 -1.87 0.24 1015.07 1.00 1058 97 52 2 FALSE 0.73
non-small cell lung cancer KRAS_G12V IRS1 114 38 Female -0.29 -1.78 0.85 1125.43 1.00 1987 112 36 2 FALSE 0.17
non-small cell lung cancer KRAS_G12V IRS1 55 35 Male -0.37 -2.02 0.97 1340.25 1.00 1457 54 34 1 FALSE 0.20
colorectal cancer KRAS_G12V IRS1 194 97 Sex:overall -0.67 -1.89 0.30 1075.91 1.00 1944 189 92 5 FALSE 0.66
non-small cell lung cancer KRAS_G12V IRS1 169 73 Sex:overall -0.35 -2.02 1.06 1520.85 1.00 3444 166 70 3 FALSE 0.18
colorectal cancer KRAS_G12V NOTCH1 113 85 Female -1.40 -3.05 -0.44 266.74 1.01 977 112 84 1 TRUE 1.44
colorectal cancer KRAS_G12V NOTCH1 114 87 Male -0.93 -1.93 0.02 478.61 1.01 1187 109 82 5 TRUE 1.15
non-small cell lung cancer KRAS_G12V NOTCH1 118 64 Female -0.68 -2.11 0.45 1160.68 1.00 2037 115 61 3 TRUE 0.53
non-small cell lung cancer KRAS_G12V NOTCH1 58 66 Male -1.50 -4.78 0.06 1086.64 1.00 1490 58 66 0 TRUE 0.63
uterine cancer KRAS_G12V NOTCH1 66 90 Female -2.08 -4.75 -0.34 1295.60 1.00 1094 65 89 1 TRUE 1.10
colorectal cancer KRAS_G12V NOTCH1 227 172 Sex:overall -1.14 -2.51 0.03 457.40 1.01 2164 221 166 6 TRUE 1.15
non-small cell lung cancer KRAS_G12V NOTCH1 176 130 Sex:overall -1.08 -3.32 0.44 1217.35 1.00 3527 173 127 3 TRUE 0.57
uterine cancer KRAS_G12V NOTCH1 66 90 Sex:overall -1.65 -6.37 3.96 1503.52 1.00 1094 65 89 1 TRUE 0.30
colorectal cancer KRAS_G12V NTRK1 102 24 Female -0.49 -1.71 0.65 533.49 1.01 928 100 22 2 TRUE 0.38
colorectal cancer KRAS_G12V NTRK1 102 40 Male -0.52 -1.73 0.52 682.73 1.00 1095 100 38 2 TRUE 0.44
non-small cell lung cancer KRAS_G12V NTRK1 114 38 Female -2.19 -5.84 -0.01 1346.69 1.00 1996 114 38 0 TRUE 0.83
non-small cell lung cancer KRAS_G12V NTRK1 55 50 Male -1.62 -4.36 0.30 1131.07 1.00 1447 54 49 1 TRUE 0.74
colorectal cancer KRAS_G12V NTRK1 204 64 Sex:overall -0.51 -1.76 0.62 789.27 1.01 2023 200 60 4 TRUE 0.39
non-small cell lung cancer KRAS_G12V NTRK1 169 88 Sex:overall -1.85 -4.90 0.41 1390.70 1.00 3443 168 87 1 TRUE 0.78
non-small cell lung cancer KRAS_G12V INPP4A 114 21 Female 0.20 -1.31 1.46 1463.22 1.00 2002 112 19 2 FALSE 0.11
non-small cell lung cancer KRAS_G12V INPP4A 55 32 Male -0.08 -1.95 1.21 1619.49 1.00 1460 54 31 1 FALSE 0.04
uterine cancer KRAS_G12V INPP4A 56 62 Female -1.74 -4.49 0.14 1127.29 1.00 954 55 61 1 FALSE 0.84
non-small cell lung cancer KRAS_G12V INPP4A 169 53 Sex:overall 0.08 -1.72 1.60 1359.18 1.00 3462 166 50 3 FALSE 0.03
uterine cancer KRAS_G12V INPP4A 56 62 Sex:overall -1.51 -6.00 3.25 1321.24 1.00 954 55 61 1 FALSE 0.30
colorectal cancer KRAS_G12V CASP8 95 38 Female -5.96 -11.51 -1.87 73.73 1.05 888 95 38 0 FALSE 1.53
colorectal cancer KRAS_G12V CASP8 99 58 Male -5.96 -11.44 -1.89 81.21 1.05 1055 99 58 0 FALSE 1.53
uterine cancer KRAS_G12V CASP8 56 63 Female -1.74 -4.42 0.09 1105.26 1.00 945 55 62 1 FALSE 0.85
colorectal cancer KRAS_G12V CASP8 194 96 Sex:overall -5.90 -11.30 -1.86 72.30 1.05 1943 194 96 0 FALSE 1.54
uterine cancer KRAS_G12V CASP8 56 63 Sex:overall -1.49 -5.96 3.27 1107.85 1.00 945 55 62 1 FALSE 0.29
colorectal cancer KRAS_G12V SETD2 102 34 Female -3.12 -6.79 -0.96 1354.01 1.00 919 102 34 0 FALSE 1.48
colorectal cancer KRAS_G12V SETD2 102 79 Male -2.77 -5.79 -0.91 1231.42 1.00 1070 101 78 1 FALSE 1.58
non-small cell lung cancer KRAS_G12V SETD2 115 131 Female -0.55 -1.42 0.20 1442.25 1.00 1928 111 127 4 FALSE 0.69
non-small cell lung cancer KRAS_G12V SETD2 55 94 Male -0.44 -1.42 0.47 1366.05 1.00 1415 52 91 3 FALSE 0.45
uterine cancer KRAS_G12V SETD2 58 89 Female -0.65 -2.08 0.50 1277.74 1.00 989 55 86 3 FALSE 0.51
colorectal cancer KRAS_G12V SETD2 204 113 Sex:overall -2.90 -6.08 -0.72 1309.23 1.00 1989 203 112 1 FALSE 1.47
non-small cell lung cancer KRAS_G12V SETD2 170 225 Sex:overall -0.51 -1.63 0.52 1499.04 1.00 3343 163 218 7 FALSE 0.44
uterine cancer KRAS_G12V SETD2 58 89 Sex:overall -0.57 -4.83 3.82 1620.39 1.00 989 55 86 3 FALSE 0.11
colorectal cancer KRAS_G12V PBRM1 102 38 Female -1.78 -3.67 -0.35 1312.71 1.00 915 101 37 1 TRUE 1.45
colorectal cancer KRAS_G12V PBRM1 102 56 Male -1.80 -3.67 -0.42 1340.61 1.00 1086 101 55 1 TRUE 1.50
non-small cell lung cancer KRAS_G12V PBRM1 116 57 Female 0.14 -1.06 1.15 1044.76 1.00 1987 111 52 5 TRUE 0.09
non-small cell lung cancer KRAS_G12V PBRM1 55 57 Male -1.31 -5.61 0.51 1329.97 1.00 1445 55 57 0 TRUE 0.36
colorectal cancer KRAS_G12V PBRM1 204 94 Sex:overall -1.76 -3.60 -0.26 1372.53 1.00 2001 202 92 2 TRUE 1.35
non-small cell lung cancer KRAS_G12V PBRM1 171 114 Sex:overall -0.52 -3.55 1.29 1402.61 1.00 3432 166 109 5 TRUE 0.19
colorectal cancer KRAS_G12V EPHA3 102 52 Female -0.13 -0.89 0.59 1382.10 1.00 905 98 48 4 FALSE 0.13
colorectal cancer KRAS_G12V EPHA3 103 61 Male -0.04 -0.77 0.69 1090.32 1.00 1082 97 55 6 FALSE 0.03
non-small cell lung cancer KRAS_G12V EPHA3 114 146 Female 0.28 -0.35 0.89 111.35 1.03 1909 104 136 10 FALSE 0.41
non-small cell lung cancer KRAS_G12V EPHA3 55 96 Male 0.22 -0.57 0.89 161.00 1.02 1412 51 92 4 FALSE 0.24
uterine cancer KRAS_G12V EPHA3 58 78 Female -6.11 -15.03 -1.20 1112.97 1.00 998 58 78 0 FALSE 0.85
colorectal cancer KRAS_G12V EPHA3 205 113 Sex:overall -0.07 -0.90 0.72 1347.08 1.00 1987 195 103 10 FALSE 0.06
non-small cell lung cancer KRAS_G12V EPHA3 169 242 Sex:overall 0.26 -0.63 1.05 201.68 1.01 3321 155 228 14 FALSE 0.25
uterine cancer KRAS_G12V EPHA3 58 78 Sex:overall -4.59 -11.37 1.91 914.08 1.00 998 58 78 0 FALSE 0.75
colorectal cancer KRAS_G12V KIT 113 23 Female -2.20 -5.33 -0.30 492.77 1.01 1017 113 23 0 TRUE 1.07
colorectal cancer KRAS_G12V KIT 113 31 Male -2.01 -4.57 -0.29 616.06 1.00 1224 112 30 1 TRUE 1.13
non-small cell lung cancer KRAS_G12V KIT 118 38 Female -0.18 -1.84 0.95 1410.67 1.00 2058 117 37 1 TRUE 0.10
non-small cell lung cancer KRAS_G12V KIT 58 43 Male 0.58 -0.56 1.67 1429.41 1.00 1514 54 39 4 TRUE 0.51
colorectal cancer KRAS_G12V KIT 226 54 Sex:overall -2.08 -4.88 -0.25 739.21 1.00 2241 225 53 1 TRUE 1.07
non-small cell lung cancer KRAS_G12V KIT 176 81 Sex:overall 0.22 -1.42 1.70 1321.18 1.00 3572 171 76 5 TRUE 0.11
colorectal cancer KRAS_G12V KDR 113 26 Female -0.86 -2.43 0.37 208.84 1.00 1018 111 24 2 TRUE 0.61
colorectal cancer KRAS_G12V KDR 113 49 Male -1.13 -2.88 -0.01 191.43 1.01 1211 112 48 1 TRUE 0.91
non-small cell lung cancer KRAS_G12V KDR 118 94 Female 0.04 -0.85 0.76 1395.01 1.00 2013 113 89 5 TRUE 0.04
non-small cell lung cancer KRAS_G12V KDR 58 60 Male 0.11 -0.90 0.99 1577.83 1.00 1494 55 57 3 TRUE 0.09
colorectal cancer KRAS_G12V KDR 226 75 Sex:overall -1.00 -2.83 0.33 343.92 1.00 2229 223 72 3 TRUE 0.64
non-small cell lung cancer KRAS_G12V KDR 176 154 Sex:overall 0.09 -1.06 1.05 1391.44 1.00 3507 168 146 8 TRUE 0.06
colorectal cancer KRAS_G12V RICTOR 102 26 Female -0.85 -2.29 0.38 1128.77 1.00 927 100 24 2 FALSE 0.67
colorectal cancer KRAS_G12V RICTOR 102 44 Male -1.08 -2.67 0.09 993.32 1.00 1097 101 43 1 FALSE 0.87
non-small cell lung cancer KRAS_G12V RICTOR 114 39 Female -1.51 -4.03 0.26 540.38 1.00 1996 113 38 1 FALSE 0.73
non-small cell lung cancer KRAS_G12V RICTOR 55 25 Male -1.73 -4.61 0.30 985.40 1.00 1472 55 25 0 FALSE 0.72
uterine cancer KRAS_G12V RICTOR 58 56 Female -1.64 -4.34 0.18 564.64 1.00 1009 57 55 1 FALSE 0.75
colorectal cancer KRAS_G12V RICTOR 204 70 Sex:overall -0.97 -2.55 0.30 1171.32 1.00 2024 201 67 3 FALSE 0.72
non-small cell lung cancer KRAS_G12V RICTOR 169 64 Sex:overall -1.60 -4.25 0.35 890.30 1.00 3468 168 63 1 FALSE 0.71
uterine cancer KRAS_G12V RICTOR 58 56 Sex:overall -1.38 -5.79 3.59 852.68 1.00 1009 57 55 1 FALSE 0.26
colorectal cancer KRAS_G12V RAD50 102 21 Female -1.95 -4.76 0.04 1437.30 1.00 931 101 20 1 FALSE 0.99
colorectal cancer KRAS_G12V RAD50 102 39 Male -2.39 -5.87 -0.44 1236.14 1.00 1097 102 39 0 FALSE 1.09
colorectal cancer KRAS_G12V RAD50 204 60 Sex:overall -2.13 -4.97 -0.13 1472.58 1.00 2028 203 59 1 FALSE 1.04
colorectal cancer KRAS_G12V CSF1R 113 21 Female -1.61 -4.42 0.06 880.78 1.00 1019 113 21 0 TRUE 0.75
colorectal cancer KRAS_G12V CSF1R 113 35 Male -1.18 -2.87 0.27 393.86 1.01 1224 111 33 2 TRUE 0.79
non-small cell lung cancer KRAS_G12V CSF1R 118 36 Female 0.66 -0.29 1.46 1133.79 1.00 2066 114 32 4 TRUE 0.85
non-small cell lung cancer KRAS_G12V CSF1R 58 33 Male 0.60 -0.53 1.50 1252.77 1.01 1519 56 31 2 TRUE 0.60
colorectal cancer KRAS_G12V CSF1R 226 56 Sex:overall -1.36 -3.39 0.36 688.11 1.00 2243 224 54 2 TRUE 0.74
non-small cell lung cancer KRAS_G12V CSF1R 176 69 Sex:overall 0.63 -0.61 1.70 1346.27 1.00 3585 170 63 6 TRUE 0.54
non-small cell lung cancer KRAS_G12V PARK2 114 39 Female -0.09 -1.69 1.08 886.15 1.00 1997 111 36 3 FALSE 0.05
non-small cell lung cancer KRAS_G12V PARK2 55 26 Male -0.67 -3.60 0.95 853.93 1.00 1469 55 26 0 FALSE 0.23
non-small cell lung cancer KRAS_G12V PARK2 169 65 Sex:overall -0.37 -2.61 1.24 936.09 1.00 3466 166 62 3 FALSE 0.15
non-small cell lung cancer KRAS_G12V NTRK2 114 36 Female -0.23 -1.69 0.98 1459.86 1.00 2002 112 34 2 FALSE 0.13
non-small cell lung cancer KRAS_G12V NTRK2 55 31 Male -0.27 -1.86 1.04 1379.59 1.00 1467 54 30 1 FALSE 0.14
non-small cell lung cancer KRAS_G12V NTRK2 169 67 Sex:overall -0.27 -1.95 1.16 1463.04 1.00 3469 166 64 3 FALSE 0.13
colorectal cancer KRAS_G12V PTCH1 102 67 Female -0.99 -2.00 -0.18 1052.94 1.00 897 98 63 4 TRUE 1.61
colorectal cancer KRAS_G12V PTCH1 102 78 Male -1.19 -2.59 -0.38 178.76 1.02 1076 101 77 1 TRUE 1.50
non-small cell lung cancer KRAS_G12V PTCH1 114 39 Female -0.34 -2.10 0.91 1160.24 1.00 1996 113 38 1 TRUE 0.18
non-small cell lung cancer KRAS_G12V PTCH1 55 23 Male 0.13 -1.59 1.54 1239.32 1.01 1474 53 21 2 TRUE 0.06
uterine cancer KRAS_G12V PTCH1 58 69 Female -5.93 -14.72 -1.09 1306.89 1.00 996 58 69 0 TRUE 0.91
colorectal cancer KRAS_G12V PTCH1 204 145 Sex:overall -1.07 -2.27 -0.19 489.10 1.01 1973 199 140 5 TRUE 1.37
non-small cell lung cancer KRAS_G12V PTCH1 169 62 Sex:overall -0.11 -1.92 1.40 1279.93 1.00 3470 166 59 3 TRUE 0.05
uterine cancer KRAS_G12V PTCH1 58 69 Sex:overall -4.47 -11.58 2.50 1357.44 1.00 996 58 69 0 TRUE 0.70
colorectal cancer KRAS_G12V TET1 95 40 Female -2.77 -5.60 -1.01 749.21 1.00 886 95 40 0 FALSE 1.76
colorectal cancer KRAS_G12V TET1 99 63 Male -2.62 -5.36 -0.91 851.21 1.00 1062 98 62 1 FALSE 1.82
non-small cell lung cancer KRAS_G12V TET1 114 63 Female 0.11 -0.95 0.97 1437.91 1.00 1967 109 58 5 FALSE 0.08
non-small cell lung cancer KRAS_G12V TET1 55 63 Male -0.35 -2.01 0.75 1303.16 1.00 1436 54 62 1 FALSE 0.21
uterine cancer KRAS_G12V TET1 56 76 Female -6.20 -17.23 -1.28 971.07 1.00 941 56 76 0 FALSE 0.67
colorectal cancer KRAS_G12V TET1 194 103 Sex:overall -2.68 -5.51 -0.94 922.95 1.00 1948 193 102 1 FALSE 1.74
non-small cell lung cancer KRAS_G12V TET1 169 126 Sex:overall -0.12 -1.65 1.10 1646.20 1.00 3403 163 120 6 FALSE 0.06
uterine cancer KRAS_G12V TET1 56 76 Sex:overall -4.35 -11.93 2.71 1373.37 1.00 941 56 76 0 FALSE 0.64
colorectal cancer KRAS_G12V FGFR2 113 21 Female -1.10 -2.92 0.19 624.04 1.01 1021 112 20 1 TRUE 0.79
colorectal cancer KRAS_G12V FGFR2 113 32 Male -1.12 -2.80 0.16 642.07 1.01 1222 112 31 1 TRUE 0.85
uterine cancer KRAS_G12V FGFR2 66 103 Female -2.34 -5.01 -0.46 1053.58 1.00 1066 65 102 1 TRUE 1.26
colorectal cancer KRAS_G12V FGFR2 226 53 Sex:overall -1.10 -2.93 0.22 782.32 1.01 2243 224 51 2 TRUE 0.79
uterine cancer KRAS_G12V FGFR2 66 103 Sex:overall -1.90 -6.68 3.20 1396.97 1.00 1066 65 102 1 TRUE 0.39
colorectal cancer KRAS_G12V TBX3 102 37 Female -0.56 -1.71 0.35 1291.14 1.00 919 100 35 2 FALSE 0.52
colorectal cancer KRAS_G12V TBX3 102 43 Male -0.48 -1.61 0.41 1054.99 1.00 1099 99 40 3 FALSE 0.44
non-small cell lung cancer KRAS_G12V TBX3 114 76 Female -0.12 -1.16 0.76 1351.05 1.00 1964 110 72 4 FALSE 0.10
non-small cell lung cancer KRAS_G12V TBX3 55 61 Male -0.15 -1.34 0.80 1423.60 1.00 1442 53 59 2 FALSE 0.11
uterine cancer KRAS_G12V TBX3 58 54 Female -6.08 -15.97 -1.08 1180.72 1.00 1006 58 54 0 FALSE 0.93
colorectal cancer KRAS_G12V TBX3 204 80 Sex:overall -0.52 -1.73 0.44 1272.72 1.00 2018 199 75 5 FALSE 0.44
non-small cell lung cancer KRAS_G12V TBX3 169 137 Sex:overall -0.14 -1.33 0.95 1189.75 1.00 3406 163 131 6 FALSE 0.09
uterine cancer KRAS_G12V TBX3 58 54 Sex:overall -4.48 -11.40 2.85 519.72 1.01 1006 58 54 0 FALSE 0.70
colorectal cancer KRAS_G12V HNF1A 113 27 Female -1.19 -3.04 0.15 1079.76 1.00 1013 112 26 1 TRUE 0.82
colorectal cancer KRAS_G12V HNF1A 113 25 Male -1.14 -2.95 0.24 1079.51 1.00 1228 112 24 1 TRUE 0.75
colorectal cancer KRAS_G12V HNF1A 226 52 Sex:overall -1.15 -2.99 0.28 1167.99 1.00 2241 224 50 2 TRUE 0.73
colorectal cancer KRAS_G12V DICER1 102 29 Female -2.29 -4.93 -0.42 816.26 1.00 922 101 28 1 TRUE 1.35
colorectal cancer KRAS_G12V DICER1 102 47 Male -2.62 -5.92 -0.67 669.78 1.00 1097 102 47 0 TRUE 1.22
non-small cell lung cancer KRAS_G12V DICER1 114 52 Female -1.04 -2.89 0.40 712.93 1.00 1987 113 51 1 TRUE 0.67
non-small cell lung cancer KRAS_G12V DICER1 55 38 Male -0.95 -2.98 0.60 891.59 1.00 1459 54 37 1 TRUE 0.54
uterine cancer KRAS_G12V DICER1 60 81 Female 0.05 -1.03 0.93 1370.33 1.00 998 55 76 5 TRUE 0.03
colorectal cancer KRAS_G12V DICER1 204 76 Sex:overall -2.43 -5.27 -0.48 931.07 1.00 2019 203 75 1 TRUE 1.28
non-small cell lung cancer KRAS_G12V DICER1 169 90 Sex:overall -0.99 -3.20 0.62 835.85 1.00 3446 167 88 2 TRUE 0.53
uterine cancer KRAS_G12V DICER1 60 81 Sex:overall 0.00 -3.94 4.08 1453.75 1.01 998 55 76 5 TRUE 0.00
colorectal cancer KRAS_G12V SMAD3 102 46 Female 0.30 -0.45 0.94 895.69 1.01 914 97 41 5 TRUE 0.40
colorectal cancer KRAS_G12V SMAD3 103 61 Male 0.38 -0.31 0.99 1143.67 1.01 1085 95 53 8 TRUE 0.62
colorectal cancer KRAS_G12V SMAD3 205 107 Sex:overall 0.34 -0.48 1.02 1251.64 1.01 1999 192 94 13 TRUE 0.42
colorectal cancer KRAS_G12V NTRK3 102 24 Female -1.01 -2.54 0.17 1456.66 1.00 928 101 23 1 FALSE 0.84
colorectal cancer KRAS_G12V NTRK3 102 46 Male -0.95 -2.41 0.19 1406.67 1.00 1093 100 44 2 FALSE 0.83
non-small cell lung cancer KRAS_G12V NTRK3 114 106 Female -0.50 -1.62 0.41 1331.81 1.00 1944 109 101 5 FALSE 0.48
non-small cell lung cancer KRAS_G12V NTRK3 55 101 Male -1.75 -5.91 -0.08 1145.43 1.00 1408 55 101 0 FALSE 0.52
colorectal cancer KRAS_G12V NTRK3 204 70 Sex:overall -1.01 -2.61 0.20 1411.76 1.00 2021 201 67 3 FALSE 0.75
non-small cell lung cancer KRAS_G12V NTRK3 169 207 Sex:overall -1.05 -3.51 0.48 1464.93 1.00 3352 164 202 5 FALSE 0.50
colorectal cancer KRAS_G12V AXIN1 102 33 Female -2.44 -5.36 -0.64 363.40 1.02 919 102 33 0 FALSE 1.28
colorectal cancer KRAS_G12V AXIN1 102 38 Male -2.23 -4.84 -0.41 675.25 1.02 1100 101 37 1 FALSE 1.34
colorectal cancer KRAS_G12V AXIN1 204 71 Sex:overall -2.34 -5.05 -0.47 705.45 1.01 2019 203 70 1 FALSE 1.31
colorectal cancer KRAS_G12V GRIN2A 102 62 Female -0.78 -1.73 0.18 169.65 1.01 895 97 57 5 FALSE 0.91
colorectal cancer KRAS_G12V GRIN2A 102 74 Male -1.14 -2.60 -0.20 627.40 1.01 1069 101 73 1 FALSE 1.17
non-small cell lung cancer KRAS_G12V GRIN2A 114 102 Female 0.21 -0.58 0.89 1343.70 1.00 1944 108 96 6 FALSE 0.24
non-small cell lung cancer KRAS_G12V GRIN2A 55 91 Male 0.43 -0.36 1.24 1092.67 1.00 1415 49 85 6 FALSE 0.55
uterine cancer KRAS_G12V GRIN2A 58 77 Female -0.48 -1.88 0.59 1362.46 1.00 999 55 74 3 FALSE 0.35
colorectal cancer KRAS_G12V GRIN2A 204 136 Sex:overall -0.97 -2.22 0.10 271.56 1.01 1964 198 130 6 FALSE 0.97
non-small cell lung cancer KRAS_G12V GRIN2A 169 193 Sex:overall 0.32 -0.56 1.28 1350.53 1.00 3359 157 181 12 FALSE 0.28
uterine cancer KRAS_G12V GRIN2A 58 77 Sex:overall -0.44 -4.86 3.76 1555.81 1.00 999 55 74 3 FALSE 0.08
colorectal cancer KRAS_G12V PALB2 102 20 Female -5.88 -12.28 -1.37 79.66 1.02 930 102 20 0 TRUE 1.33
colorectal cancer KRAS_G12V PALB2 102 36 Male -5.88 -12.06 -1.34 105.72 1.02 1098 102 36 0 TRUE 1.36
non-small cell lung cancer KRAS_G12V PALB2 114 31 Female 0.36 -0.86 1.38 1336.09 1.00 2007 111 28 3 TRUE 0.27
non-small cell lung cancer KRAS_G12V PALB2 55 29 Male 0.14 -1.44 1.40 1463.84 1.00 1468 54 28 1 TRUE 0.07
colorectal cancer KRAS_G12V PALB2 204 56 Sex:overall -5.84 -11.91 -1.37 78.18 1.02 2028 204 56 0 TRUE 1.34
non-small cell lung cancer KRAS_G12V PALB2 169 60 Sex:overall 0.24 -1.30 1.55 1533.75 1.00 3475 165 56 4 TRUE 0.12
colorectal cancer KRAS_G12V CTCF 102 40 Female -0.87 -2.17 0.12 738.38 1.00 917 100 38 2 FALSE 0.87
colorectal cancer KRAS_G12V CTCF 102 50 Male -0.88 -2.13 0.10 900.27 1.00 1090 100 48 2 FALSE 0.90
uterine cancer KRAS_G12V CTCF 58 168 Female -0.18 -0.98 0.56 356.05 1.01 910 50 160 8 FALSE 0.19
colorectal cancer KRAS_G12V CTCF 204 90 Sex:overall -0.86 -2.16 0.25 894.99 1.00 2007 200 86 4 FALSE 0.81
uterine cancer KRAS_G12V CTCF 58 168 Sex:overall -0.10 -4.55 4.15 1507.48 1.00 910 50 160 8 FALSE 0.02
colorectal cancer KRAS_G12V CDH1 114 21 Female -0.03 -1.14 1.01 905.06 1.00 1026 111 18 3 TRUE 0.02
colorectal cancer KRAS_G12V CDH1 113 33 Male -0.17 -1.34 0.89 748.03 1.00 1222 111 31 2 TRUE 0.12
colorectal cancer KRAS_G12V CDH1 227 54 Sex:overall -0.09 -1.30 1.03 937.81 1.00 2248 222 49 5 TRUE 0.06
colorectal cancer KRAS_G12V CDK12 102 42 Female -1.26 -2.70 -0.12 599.04 1.00 914 101 41 1 FALSE 1.26
colorectal cancer KRAS_G12V CDK12 102 48 Male -1.18 -2.56 -0.04 647.95 1.00 1093 100 46 2 FALSE 1.22
non-small cell lung cancer KRAS_G12V CDK12 114 31 Female -4.57 -11.21 -0.70 582.44 1.01 2003 114 31 0 FALSE 1.00
non-small cell lung cancer KRAS_G12V CDK12 55 28 Male -4.57 -11.71 -0.58 642.65 1.01 1468 55 28 0 FALSE 0.96
colorectal cancer KRAS_G12V CDK12 204 90 Sex:overall -1.21 -2.74 0.02 753.00 1.00 2007 201 87 3 FALSE 1.14
non-small cell lung cancer KRAS_G12V CDK12 169 59 Sex:overall -4.49 -11.11 -0.51 649.65 1.01 3471 169 59 0 FALSE 0.99
non-small cell lung cancer KRAS_G12V STK11 119 295 Female 0.53 0.07 0.96 1500.92 1.00 1834 96 272 23 TRUE 1.71
non-small cell lung cancer KRAS_G12V STK11 59 248 Male 0.70 0.21 1.24 1359.77 1.00 1325 42 231 17 TRUE 2.11
non-small cell lung cancer KRAS_G12V STK11 178 543 Sex:overall 0.60 -0.12 1.34 1463.30 1.00 3159 138 503 40 TRUE 0.90
colorectal cancer KRAS_G12V DNMT1 95 39 Female -1.55 -3.35 -0.07 595.32 1.00 887 93 37 2 FALSE 1.22
colorectal cancer KRAS_G12V DNMT1 99 51 Male -1.89 -4.51 -0.47 496.75 1.01 1060 99 51 0 FALSE 1.16
colorectal cancer KRAS_G12V DNMT1 194 90 Sex:overall -1.71 -3.86 -0.24 498.37 1.01 1947 192 88 2 FALSE 1.28
colorectal cancer KRAS_G12V BRD4 102 31 Female -0.79 -2.09 0.34 1012.34 1.00 920 100 29 2 FALSE 0.70
colorectal cancer KRAS_G12V BRD4 102 57 Male -0.89 -2.10 0.10 798.95 1.00 1083 100 55 2 FALSE 0.90
non-small cell lung cancer KRAS_G12V BRD4 114 27 Female -1.28 -4.32 0.64 1142.01 1.00 2009 113 26 1 FALSE 0.52
non-small cell lung cancer KRAS_G12V BRD4 55 26 Male -1.68 -5.22 0.46 1110.45 1.00 1469 55 26 0 FALSE 0.56
uterine cancer KRAS_G12V BRD4 58 70 Female -5.86 -15.57 -1.15 964.49 1.00 993 58 70 0 FALSE 0.67
colorectal cancer KRAS_G12V BRD4 204 88 Sex:overall -0.83 -2.19 0.38 1032.00 1.00 2003 200 84 4 FALSE 0.66
non-small cell lung cancer KRAS_G12V BRD4 169 53 Sex:overall -1.45 -4.70 0.66 1115.42 1.00 3478 168 52 1 FALSE 0.54
uterine cancer KRAS_G12V BRD4 58 70 Sex:overall -4.32 -12.08 2.63 1157.04 1.00 993 58 70 0 FALSE 0.65
colorectal cancer KRAS_G12V ASXL1 102 49 Female -1.71 -5.69 -0.17 836.05 1.00 906 102 49 0 TRUE 0.63
colorectal cancer KRAS_G12V ASXL1 102 60 Male -0.52 -1.60 0.53 1089.96 1.00 1080 97 55 5 TRUE 0.47
non-small cell lung cancer KRAS_G12V ASXL1 114 40 Female 0.65 -0.35 1.55 1170.22 1.00 1999 109 35 5 TRUE 0.75
non-small cell lung cancer KRAS_G12V ASXL1 55 46 Male -0.01 -1.81 1.12 1445.48 1.00 1463 54 45 1 TRUE 0.00
uterine cancer KRAS_G12V ASXL1 58 60 Female -1.67 -4.40 0.09 1601.67 1.00 1006 57 59 1 TRUE 0.83
colorectal cancer KRAS_G12V ASXL1 204 109 Sex:overall -1.08 -3.72 0.42 1205.29 1.00 1986 199 104 5 TRUE 0.55
non-small cell lung cancer KRAS_G12V ASXL1 169 86 Sex:overall 0.32 -1.35 1.74 1475.81 1.00 3462 163 80 6 TRUE 0.17
uterine cancer KRAS_G12V ASXL1 58 60 Sex:overall -1.34 -5.78 3.19 1485.68 1.00 1006 57 59 1 TRUE 0.27
colorectal cancer KRAS_G12V EP300 102 53 Female -0.81 -1.82 -0.05 42.43 1.04 911 99 50 3 TRUE 1.19
colorectal cancer KRAS_G12V EP300 102 72 Male -0.88 -1.96 -0.16 13.59 1.08 1073 100 70 2 TRUE 1.22
non-small cell lung cancer KRAS_G12V EP300 115 54 Female -0.50 -2.08 0.63 882.07 1.00 1988 112 51 3 TRUE 0.33
non-small cell lung cancer KRAS_G12V EP300 55 54 Male -1.30 -4.36 0.34 1089.68 1.00 1445 55 54 0 TRUE 0.54
uterine cancer KRAS_G12V EP300 59 103 Female -0.19 -1.25 0.71 1323.40 1.00 978 54 98 5 TRUE 0.15
colorectal cancer KRAS_G12V EP300 204 125 Sex:overall -0.83 -1.97 -0.03 45.26 1.04 1984 199 120 5 TRUE 1.01
non-small cell lung cancer KRAS_G12V EP300 170 108 Sex:overall -0.89 -3.15 0.79 1294.90 1.00 3433 167 105 3 TRUE 0.42
uterine cancer KRAS_G12V EP300 59 103 Sex:overall -0.09 -4.24 4.09 1487.46 1.00 978 54 98 5 TRUE 0.02
colorectal cancer KRAS_G12V ERBB4 114 60 Female -0.49 -1.34 0.31 1402.77 1.00 989 109 55 5 TRUE 0.61
colorectal cancer KRAS_G12V ERBB4 113 78 Male -0.62 -1.49 0.10 1304.11 1.00 1189 110 75 3 TRUE 0.88
non-small cell lung cancer KRAS_G12V ERBB4 119 108 Female -0.08 -0.97 0.70 1428.25 1.00 2007 112 101 7 TRUE 0.07
non-small cell lung cancer KRAS_G12V ERBB4 58 85 Male -1.41 -5.69 0.24 1139.07 1.00 1480 58 85 0 TRUE 0.45
colorectal cancer KRAS_G12V ERBB4 227 138 Sex:overall -0.56 -1.52 0.31 1411.28 1.00 2178 219 130 8 TRUE 0.62
non-small cell lung cancer KRAS_G12V ERBB4 177 193 Sex:overall -0.65 -3.17 0.79 1205.27 1.00 3487 170 186 7 TRUE 0.28
colorectal cancer KRAS_G12V MDC1 95 27 Female -2.19 -5.07 -0.32 812.82 1.00 896 94 26 1 FALSE 1.14
colorectal cancer KRAS_G12V MDC1 99 38 Male -2.38 -5.55 -0.38 835.16 1.00 1073 99 38 0 FALSE 1.12
non-small cell lung cancer KRAS_G12V MDC1 115 52 Female -0.22 -1.42 0.79 1289.86 1.00 1977 112 49 3 FALSE 0.15
non-small cell lung cancer KRAS_G12V MDC1 55 43 Male -0.35 -1.84 0.83 1316.35 1.00 1453 54 42 1 FALSE 0.22
colorectal cancer KRAS_G12V MDC1 194 65 Sex:overall -2.26 -5.14 -0.28 784.25 1.00 1969 193 64 1 FALSE 1.13
non-small cell lung cancer KRAS_G12V MDC1 170 95 Sex:overall -0.28 -1.76 0.87 1291.97 1.00 3430 166 91 4 FALSE 0.17
colorectal cancer KRAS_G12V RECQL4 95 30 Female -2.63 -5.40 -0.66 1162.55 1.00 894 95 30 0 TRUE 1.43
colorectal cancer KRAS_G12V RECQL4 99 51 Male -2.46 -5.24 -0.53 1232.39 1.00 1061 98 50 1 TRUE 1.42
non-small cell lung cancer KRAS_G12V RECQL4 114 36 Female -1.27 -4.98 0.50 1226.27 1.00 1988 114 36 0 TRUE 0.44
non-small cell lung cancer KRAS_G12V RECQL4 55 28 Male -0.28 -2.26 1.31 1102.22 1.00 1464 53 26 2 TRUE 0.12
colorectal cancer KRAS_G12V RECQL4 194 81 Sex:overall -2.53 -5.23 -0.48 1242.68 1.00 1955 193 80 1 TRUE 1.41
non-small cell lung cancer KRAS_G12V RECQL4 169 64 Sex:overall -0.73 -3.17 1.08 1302.84 1.00 3452 167 62 2 TRUE 0.28
colorectal cancer KRAS_G12V MED12 102 54 Female -0.42 -1.29 0.42 953.37 1.00 906 98 50 4 TRUE 0.48
colorectal cancer KRAS_G12V MED12 102 54 Male -0.45 -1.37 0.37 1298.49 1.00 1088 99 51 3 TRUE 0.50
non-small cell lung cancer KRAS_G12V MED12 114 137 Female -0.71 -1.76 0.18 1514.37 1.00 1912 110 133 4 TRUE 0.82
non-small cell lung cancer KRAS_G12V MED12 55 39 Male -0.71 -2.56 0.74 1442.04 1.00 1459 54 38 1 TRUE 0.41
uterine cancer KRAS_G12V MED12 58 140 Female -0.76 -1.94 0.19 591.74 1.01 947 54 136 4 TRUE 0.77
colorectal cancer KRAS_G12V MED12 204 108 Sex:overall -0.42 -1.34 0.51 1138.05 1.00 1994 197 101 7 TRUE 0.41
non-small cell lung cancer KRAS_G12V MED12 169 176 Sex:overall -0.69 -2.50 0.87 1428.46 1.00 3371 164 171 5 TRUE 0.38
uterine cancer KRAS_G12V MED12 58 140 Sex:overall -0.60 -4.61 3.99 1348.14 1.00 947 54 136 4 TRUE 0.12
colorectal cancer KRAS_G12V ERCC5 95 31 Female -0.79 -2.50 0.58 271.73 1.00 897 94 30 1 TRUE 0.51
colorectal cancer KRAS_G12V ERCC5 99 27 Male -0.60 -2.04 0.68 332.00 1.00 1077 97 25 2 TRUE 0.41
non-small cell lung cancer KRAS_G12V ERCC5 114 39 Female -5.10 -12.47 -0.71 269.56 1.00 1983 114 39 0 TRUE 1.01
non-small cell lung cancer KRAS_G12V ERCC5 55 34 Male -5.11 -12.37 -0.83 292.70 1.00 1461 55 34 0 TRUE 1.02
uterine cancer KRAS_G12V ERCC5 56 52 Female -1.51 -4.33 0.28 1050.58 1.00 957 55 51 1 TRUE 0.69
colorectal cancer KRAS_G12V ERCC5 194 58 Sex:overall -0.68 -2.26 0.69 299.86 1.00 1974 191 55 3 TRUE 0.44
non-small cell lung cancer KRAS_G12V ERCC5 169 73 Sex:overall -5.00 -12.19 -0.61 268.01 1.00 3444 169 73 0 TRUE 1.01
uterine cancer KRAS_G12V ERCC5 56 52 Sex:overall -1.26 -5.93 3.68 1343.96 1.00 957 55 51 1 TRUE 0.24
colorectal cancer KRAS_G12V PIK3CD 95 34 Female -2.34 -5.39 -0.43 595.84 1.00 891 94 33 1 FALSE 1.22
colorectal cancer KRAS_G12V PIK3CD 99 35 Male -2.60 -6.00 -0.64 394.48 1.00 1071 99 35 0 FALSE 1.23
colorectal cancer KRAS_G12V PIK3CD 194 69 Sex:overall -2.45 -5.74 -0.46 568.41 1.01 1962 193 68 1 FALSE 1.24
colorectal cancer KRAS_G12V BRCA1 102 28 Female -1.88 -4.78 -0.24 468.87 1.00 923 102 28 0 TRUE 0.97
colorectal cancer KRAS_G12V BRCA1 102 51 Male -1.44 -3.16 -0.14 505.18 1.01 1094 100 49 2 TRUE 1.14
non-small cell lung cancer KRAS_G12V BRCA1 114 50 Female -0.74 -2.45 0.44 1569.39 1.00 1987 113 49 1 TRUE 0.50
non-small cell lung cancer KRAS_G12V BRCA1 55 47 Male -0.41 -1.98 0.83 1397.09 1.00 1452 53 45 2 TRUE 0.26
colorectal cancer KRAS_G12V BRCA1 204 79 Sex:overall -1.65 -3.80 -0.16 514.94 1.01 2017 202 77 2 TRUE 0.99
non-small cell lung cancer KRAS_G12V BRCA1 169 97 Sex:overall -0.58 -2.36 0.81 1418.34 1.00 3439 166 94 3 TRUE 0.34
colorectal cancer KRAS_G12V RBM10 102 41 Female -1.55 -3.45 -0.18 853.96 1.00 915 101 40 1 FALSE 1.20
colorectal cancer KRAS_G12V RBM10 102 31 Male -1.49 -3.43 -0.12 1187.78 1.00 1101 101 30 1 FALSE 1.10
non-small cell lung cancer KRAS_G12V RBM10 114 239 Female -0.06 -0.63 0.50 1469.19 1.00 1822 103 228 11 FALSE 0.07
non-small cell lung cancer KRAS_G12V RBM10 55 144 Male 0.25 -0.42 0.92 1404.81 1.00 1362 47 136 8 FALSE 0.31
uterine cancer KRAS_G12V RBM10 58 54 Female -0.59 -2.48 0.74 1293.35 1.00 1009 56 52 2 FALSE 0.33
colorectal cancer KRAS_G12V RBM10 204 72 Sex:overall -1.50 -3.41 0.01 1248.66 1.00 2016 202 70 2 FALSE 1.07
non-small cell lung cancer KRAS_G12V RBM10 169 383 Sex:overall 0.10 -0.84 1.13 1558.46 1.00 3184 150 364 19 FALSE 0.08
uterine cancer KRAS_G12V RBM10 58 54 Sex:overall -0.49 -4.78 3.99 1237.63 1.00 1009 56 52 2 FALSE 0.09
colorectal cancer KRAS_G12V TSC1 102 27 Female -0.96 -2.51 0.28 1335.03 1.00 925 101 26 1 TRUE 0.76
colorectal cancer KRAS_G12V TSC1 102 40 Male -0.86 -2.33 0.27 1283.33 1.00 1102 100 38 2 TRUE 0.71
non-small cell lung cancer KRAS_G12V TSC1 114 30 Female 0.14 -1.33 1.31 701.11 1.01 2007 111 27 3 TRUE 0.08
non-small cell lung cancer KRAS_G12V TSC1 55 27 Male -0.53 -3.50 1.06 1368.50 1.00 1468 55 27 0 TRUE 0.19
uterine cancer KRAS_G12V TSC1 58 62 Female -0.22 -1.59 0.86 736.73 1.00 1007 55 59 3 TRUE 0.14
colorectal cancer KRAS_G12V TSC1 204 67 Sex:overall -0.90 -2.48 0.32 1250.19 1.00 2027 201 64 3 TRUE 0.68
non-small cell lung cancer KRAS_G12V TSC1 169 57 Sex:overall -0.16 -2.44 1.38 1399.42 1.00 3475 166 54 3 TRUE 0.06
uterine cancer KRAS_G12V TSC1 58 62 Sex:overall -0.14 -4.17 4.05 1380.87 1.00 1007 55 59 3 TRUE 0.03
colorectal cancer KRAS_G12V FLCN 102 30 Female -1.63 -5.01 0.01 926.57 1.00 920 102 30 0 TRUE 0.72
colorectal cancer KRAS_G12V FLCN 102 24 Male -0.96 -2.90 0.57 1407.63 1.00 1113 100 22 2 TRUE 0.56
colorectal cancer KRAS_G12V FLCN 204 54 Sex:overall -1.25 -3.75 0.43 1172.01 1.00 2033 202 52 2 TRUE 0.63
colorectal cancer KRAS_G12V NF1 102 55 Female -1.77 -3.36 -0.60 1091.01 1.00 905 101 54 1 TRUE 1.93
colorectal cancer KRAS_G12V NF1 102 87 Male -1.69 -3.12 -0.57 950.54 1.00 1071 100 85 2 TRUE 1.95
non-small cell lung cancer KRAS_G12V NF1 115 165 Female -0.31 -1.13 0.37 485.79 1.00 1899 107 157 8 TRUE 0.36
non-small cell lung cancer KRAS_G12V NF1 55 150 Male -0.69 -1.94 0.21 637.89 1.00 1368 53 148 2 TRUE 0.67
uterine cancer KRAS_G12V NF1 58 123 Female -5.91 -15.29 -1.37 48.48 1.06 974 58 123 0 TRUE 0.86
colorectal cancer KRAS_G12V NF1 204 142 Sex:overall -1.71 -3.22 -0.44 1035.20 1.00 1976 201 139 3 TRUE 1.79
non-small cell lung cancer KRAS_G12V NF1 170 315 Sex:overall -0.50 -1.78 0.47 1164.34 1.00 3267 160 305 10 TRUE 0.41
uterine cancer KRAS_G12V NF1 58 123 Sex:overall -4.55 -12.22 1.81 116.90 1.03 974 58 123 0 TRUE 0.71
colorectal cancer KRAS_G12V FLT1 102 30 Female -2.77 -5.82 -0.74 1378.88 1.00 923 102 30 0 FALSE 1.40
colorectal cancer KRAS_G12V FLT1 102 52 Male -2.54 -4.96 -0.64 981.74 1.00 1090 101 51 1 FALSE 1.70
non-small cell lung cancer KRAS_G12V FLT1 114 75 Female 0.27 -0.57 1.05 1481.28 1.00 1971 108 69 6 FALSE 0.30
non-small cell lung cancer KRAS_G12V FLT1 55 61 Male 0.11 -0.99 1.02 1424.14 1.00 1441 53 59 2 FALSE 0.08
uterine cancer KRAS_G12V FLT1 58 56 Female -5.55 -15.01 -0.85 1237.43 1.00 1008 58 56 0 FALSE 0.76
colorectal cancer KRAS_G12V FLT1 204 82 Sex:overall -2.65 -5.59 -0.63 1401.56 1.00 2013 203 81 1 FALSE 1.56
non-small cell lung cancer KRAS_G12V FLT1 169 136 Sex:overall 0.16 -1.02 1.21 1474.66 1.00 3412 161 128 8 FALSE 0.12
uterine cancer KRAS_G12V FLT1 58 56 Sex:overall -4.07 -11.74 2.35 1156.85 1.00 1008 58 56 0 FALSE 0.62
colorectal cancer KRAS_G12V RPTOR 102 32 Female 0.18 -0.75 0.98 663.36 1.00 922 97 27 5 FALSE 0.16
colorectal cancer KRAS_G12V RPTOR 102 38 Male -0.04 -1.17 0.81 557.89 1.00 1101 100 36 2 FALSE 0.03
non-small cell lung cancer KRAS_G12V RPTOR 115 34 Female 1.02 -0.01 1.97 1161.78 1.00 2005 109 28 6 FALSE 1.39
non-small cell lung cancer KRAS_G12V RPTOR 55 31 Male -0.56 -5.23 1.25 1091.15 1.00 1465 55 31 0 FALSE 0.14
colorectal cancer KRAS_G12V RPTOR 204 70 Sex:overall 0.07 -1.02 0.94 603.87 1.00 2023 197 63 7 FALSE 0.05
non-small cell lung cancer KRAS_G12V RPTOR 170 65 Sex:overall 0.19 -2.68 1.98 1276.90 1.00 3470 164 59 6 FALSE 0.06
colorectal cancer KRAS_G12V RASA1 102 30 Female -0.66 -1.95 0.47 1202.54 1.00 924 100 28 2 FALSE 0.56
colorectal cancer KRAS_G12V RASA1 102 43 Male -0.66 -1.88 0.41 1029.84 1.00 1103 100 41 2 FALSE 0.59
non-small cell lung cancer KRAS_G12V RASA1 114 47 Female -0.75 -2.56 0.46 1134.40 1.00 1989 113 46 1 FALSE 0.47
non-small cell lung cancer KRAS_G12V RASA1 55 51 Male -0.40 -1.84 0.85 1434.75 1.00 1446 53 49 2 FALSE 0.25
uterine cancer KRAS_G12V RASA1 58 105 Female -1.26 -3.08 0.06 1187.21 1.00 986 56 103 2 FALSE 0.97
colorectal cancer KRAS_G12V RASA1 204 73 Sex:overall -0.66 -1.99 0.55 1199.44 1.00 2027 200 69 4 FALSE 0.49
non-small cell lung cancer KRAS_G12V RASA1 169 98 Sex:overall -0.56 -2.29 0.92 1314.90 1.00 3435 166 95 3 FALSE 0.30
uterine cancer KRAS_G12V RASA1 58 105 Sex:overall -1.06 -5.53 4.05 1448.46 1.00 986 56 103 2 FALSE 0.20
colorectal cancer KRAS_G12V EPHA5 102 58 Female -0.64 -1.70 0.34 1222.16 1.00 902 97 53 5 FALSE 0.67
colorectal cancer KRAS_G12V EPHA5 102 86 Male -1.29 -3.01 -0.22 936.41 1.00 1065 101 85 1 FALSE 1.12
non-small cell lung cancer KRAS_G12V EPHA5 115 147 Female 0.03 -0.71 0.64 1243.91 1.00 1903 108 140 7 FALSE 0.03
non-small cell lung cancer KRAS_G12V EPHA5 55 113 Male 0.33 -0.38 1.06 1177.05 1.00 1402 48 106 7 FALSE 0.43
uterine cancer KRAS_G12V EPHA5 58 98 Female -0.72 -2.11 0.35 1158.16 1.00 988 55 95 3 FALSE 0.61
colorectal cancer KRAS_G12V EPHA5 204 144 Sex:overall -0.96 -2.58 0.25 1401.14 1.00 1967 198 138 6 FALSE 0.72
non-small cell lung cancer KRAS_G12V EPHA5 170 260 Sex:overall 0.17 -0.80 1.03 1428.19 1.00 3305 156 246 14 FALSE 0.13
uterine cancer KRAS_G12V EPHA5 58 98 Sex:overall -0.62 -4.94 4.05 1503.27 1.00 988 55 95 3 FALSE 0.12
colorectal cancer KRAS_G12V AR 102 59 Female -0.33 -1.14 0.43 1131.64 1.00 901 97 54 5 TRUE 0.40
colorectal cancer KRAS_G12V AR 102 57 Male -0.41 -1.29 0.32 1147.83 1.00 1083 99 54 3 TRUE 0.50
non-small cell lung cancer KRAS_G12V AR 114 81 Female 0.28 -0.55 1.06 1349.34 1.00 1967 108 75 6 TRUE 0.29
non-small cell lung cancer KRAS_G12V AR 55 29 Male 0.04 -1.54 1.25 1441.49 1.00 1467 54 28 1 TRUE 0.02
uterine cancer KRAS_G12V AR 59 65 Female -0.30 -1.78 0.87 1010.96 1.00 1000 56 62 3 TRUE 0.18
colorectal cancer KRAS_G12V AR 204 116 Sex:overall -0.37 -1.27 0.49 1283.21 1.00 1984 196 108 8 TRUE 0.39
non-small cell lung cancer KRAS_G12V AR 169 110 Sex:overall 0.16 -1.30 1.50 1258.42 1.00 3434 162 103 7 TRUE 0.09
uterine cancer KRAS_G12V AR 59 65 Sex:overall -0.22 -5.16 4.14 1563.75 1.00 1000 56 62 3 TRUE 0.04
colorectal cancer KRAS_G12V GNAS 113 41 Female -0.04 -0.94 0.78 1269.93 1.00 1007 109 37 4 TRUE 0.03
colorectal cancer KRAS_G12V GNAS 113 34 Male -0.06 -1.03 0.83 1451.58 1.00 1219 110 31 3 TRUE 0.05
pancreatic cancer KRAS_G12V GNAS 187 25 Female -0.27 -1.01 0.42 1299.80 1.00 550 181 19 6 TRUE 0.36
pancreatic cancer KRAS_G12V GNAS 214 37 Male -0.32 -1.01 0.30 1270.14 1.01 593 207 30 7 TRUE 0.48
colorectal cancer KRAS_G12V GNAS 226 75 Sex:overall -0.04 -1.18 0.92 1295.56 1.00 2226 219 68 7 TRUE 0.03
pancreatic cancer KRAS_G12V GNAS 401 62 Sex:overall -0.30 -1.12 0.43 1291.84 1.00 1143 388 49 13 TRUE 0.35
colorectal cancer KRAS_G12V ASXL2 102 20 Female -0.93 -2.79 0.69 1339.07 1.00 931 100 18 2 FALSE 0.49
colorectal cancer KRAS_G12V ASXL2 102 51 Male -2.35 -6.60 -0.47 1272.60 1.00 1100 102 51 0 FALSE 0.83
non-small cell lung cancer KRAS_G12V ASXL2 114 32 Female -4.85 -11.11 -0.71 313.39 1.01 2003 114 32 0 FALSE 1.03
non-small cell lung cancer KRAS_G12V ASXL2 55 31 Male -4.84 -11.39 -0.60 326.94 1.00 1465 55 31 0 FALSE 1.00
colorectal cancer KRAS_G12V ASXL2 204 71 Sex:overall -1.59 -4.36 0.52 1430.97 1.00 2031 202 69 2 FALSE 0.68
non-small cell lung cancer KRAS_G12V ASXL2 169 63 Sex:overall -4.76 -11.11 -0.55 313.05 1.00 3468 169 63 0 FALSE 1.02
colorectal cancer KRAS_G12V SF3B1 102 18 Female -1.30 -3.35 0.40 1204.99 1.00 933 101 17 1 TRUE 0.78
colorectal cancer KRAS_G12V SF3B1 102 52 Male -1.54 -3.59 -0.11 1225.64 1.00 1095 101 51 1 TRUE 1.10
non-small cell lung cancer KRAS_G12V SF3B1 114 55 Female 0.30 -0.82 1.20 261.72 1.01 1987 109 50 5 TRUE 0.24
non-small cell lung cancer KRAS_G12V SF3B1 55 32 Male -0.46 -3.76 1.00 311.28 1.02 1464 55 32 0 TRUE 0.14
colorectal cancer KRAS_G12V SF3B1 204 70 Sex:overall -1.37 -3.36 0.50 1266.65 1.00 2028 202 68 2 TRUE 0.80
non-small cell lung cancer KRAS_G12V SF3B1 169 87 Sex:overall -0.08 -2.19 1.25 278.79 1.02 3451 164 82 5 TRUE 0.03
colorectal cancer KRAS_G12V MLH1 113 20 Female -2.09 -4.35 -0.03 81.53 1.04 1025 112 19 1 TRUE 1.15
colorectal cancer KRAS_G12V MLH1 113 36 Male -2.44 -5.41 -0.33 251.53 1.02 1218 113 36 0 TRUE 1.23
colorectal cancer KRAS_G12V MLH1 226 56 Sex:overall -2.22 -4.60 -0.08 97.13 1.04 2243 225 55 1 TRUE 1.14
colorectal cancer KRAS_G12V ROS1 102 32 Female -2.41 -5.14 -0.51 1379.89 1.00 919 101 31 1 TRUE 1.40
colorectal cancer KRAS_G12V ROS1 102 71 Male -2.96 -6.08 -1.03 1270.06 1.01 1081 102 71 0 TRUE 1.51
non-small cell lung cancer KRAS_G12V ROS1 114 57 Female -5.34 -12.94 -1.31 162.91 1.03 1978 114 57 0 TRUE 1.02
non-small cell lung cancer KRAS_G12V ROS1 55 54 Male -5.34 -13.40 -1.26 170.09 1.03 1444 55 54 0 TRUE 0.99
uterine cancer KRAS_G12V ROS1 58 100 Female -1.23 -3.14 0.06 1433.49 1.00 1004 56 98 2 TRUE 0.89
colorectal cancer KRAS_G12V ROS1 204 103 Sex:overall -2.65 -5.68 -0.63 1338.38 1.00 2000 203 102 1 TRUE 1.44
non-small cell lung cancer KRAS_G12V ROS1 169 111 Sex:overall -5.24 -12.61 -1.14 175.32 1.03 3422 169 111 0 TRUE 1.00
uterine cancer KRAS_G12V ROS1 58 100 Sex:overall -0.98 -5.25 3.92 1421.27 1.00 1004 56 98 2 TRUE 0.18
colorectal cancer KRAS_G12V PIK3R2 102 24 Female -1.11 -4.32 0.35 1072.59 1.00 927 102 24 0 FALSE 0.43
colorectal cancer KRAS_G12V PIK3R2 102 28 Male -0.45 -1.82 0.77 491.47 1.00 1107 99 25 3 FALSE 0.31
colorectal cancer KRAS_G12V PIK3R2 204 52 Sex:overall -0.76 -2.86 0.62 1084.13 1.00 2034 201 49 3 FALSE 0.38
colorectal cancer KRAS_G12V FLT3 113 19 Female -0.09 -1.44 1.04 441.05 1.00 1024 110 16 3 TRUE 0.05
colorectal cancer KRAS_G12V FLT3 113 33 Male -0.49 -2.10 0.72 356.05 1.00 1226 112 32 1 TRUE 0.30
non-small cell lung cancer KRAS_G12V FLT3 118 42 Female -0.10 -1.37 0.92 1233.35 1.00 2058 116 40 2 TRUE 0.07
non-small cell lung cancer KRAS_G12V FLT3 58 39 Male 0.02 -1.33 1.09 1088.56 1.00 1515 56 37 2 TRUE 0.01
uterine cancer KRAS_G12V FLT3 66 61 Female -5.94 -15.75 -1.07 923.77 1.00 1116 66 61 0 TRUE 0.71
colorectal cancer KRAS_G12V FLT3 226 52 Sex:overall -0.30 -1.81 0.99 454.77 1.00 2250 222 48 4 TRUE 0.16
non-small cell lung cancer KRAS_G12V FLT3 176 81 Sex:overall -0.04 -1.40 1.15 1266.64 1.00 3573 172 77 4 TRUE 0.02
uterine cancer KRAS_G12V FLT3 66 61 Sex:overall -4.24 -10.80 2.41 1270.32 1.00 1116 66 61 0 TRUE 0.69
colorectal cancer KRAS_G12V MSH2 103 34 Female -0.47 -1.53 0.49 1306.90 1.00 925 100 31 3 TRUE 0.43
colorectal cancer KRAS_G12V MSH2 102 49 Male -0.57 -1.68 0.35 1241.86 1.00 1097 100 47 2 TRUE 0.57
non-small cell lung cancer KRAS_G12V MSH2 114 26 Female -0.54 -2.46 0.87 1154.01 1.00 2008 113 25 1 TRUE 0.27
non-small cell lung cancer KRAS_G12V MSH2 55 30 Male -0.48 -2.45 0.97 1395.45 1.00 1470 54 29 1 TRUE 0.23
uterine cancer KRAS_G12V MSH2 58 66 Female -1.71 -4.40 0.10 1275.80 1.00 1004 57 65 1 TRUE 0.83
colorectal cancer KRAS_G12V MSH2 205 83 Sex:overall -0.53 -1.64 0.49 1450.01 1.00 2022 200 78 5 TRUE 0.45
non-small cell lung cancer KRAS_G12V MSH2 169 56 Sex:overall -0.51 -2.65 1.19 1372.67 1.00 3478 167 54 2 TRUE 0.23
uterine cancer KRAS_G12V MSH2 58 66 Sex:overall -1.32 -6.03 3.93 1495.33 1.00 1004 57 65 1 TRUE 0.24
non-small cell lung cancer KRAS_G12V DIS3 114 29 Female 0.55 -0.83 1.72 543.64 1.01 2008 110 25 4 FALSE 0.40
non-small cell lung cancer KRAS_G12V DIS3 55 36 Male -0.91 -5.09 0.95 1228.56 1.00 1461 55 36 0 FALSE 0.24
non-small cell lung cancer KRAS_G12V DIS3 169 65 Sex:overall -0.17 -3.44 1.70 1553.00 1.00 3469 165 61 4 FALSE 0.05
colorectal cancer KRAS_G12V AXL 102 30 Female -1.42 -3.17 0.12 1142.32 1.00 922 100 28 2 FALSE 0.99
colorectal cancer KRAS_G12V AXL 102 58 Male -2.28 -5.61 -0.60 1222.07 1.00 1086 102 58 0 FALSE 1.06
colorectal cancer KRAS_G12V AXL 204 88 Sex:overall -1.84 -4.32 -0.08 1360.69 1.00 2008 202 86 2 FALSE 1.05
pancreatic cancer KRAS_G12V DAXX 172 21 Female -1.82 -3.17 -0.52 876.32 1.00 506 170 19 2 TRUE 2.16
pancreatic cancer KRAS_G12V DAXX 203 32 Male -2.01 -3.49 -0.82 976.48 1.00 546 202 31 1 TRUE 2.58
pancreatic cancer KRAS_G12V DAXX 375 53 Sex:overall -1.90 -3.38 -0.59 1066.47 1.00 1052 372 50 3 TRUE 2.13
colorectal cancer KRAS_G12V PIK3CG 102 39 Female -0.30 -1.29 0.58 311.61 1.00 914 99 36 3 FALSE 0.27
colorectal cancer KRAS_G12V PIK3CG 102 68 Male -0.24 -1.10 0.59 219.75 1.00 1081 97 63 5 FALSE 0.23
non-small cell lung cancer KRAS_G12V PIK3CG 114 88 Female 0.23 -0.58 1.01 1412.47 1.00 1957 107 81 7 FALSE 0.23
non-small cell lung cancer KRAS_G12V PIK3CG 55 92 Male -0.21 -1.40 0.72 1298.23 1.00 1419 53 90 2 FALSE 0.16
uterine cancer KRAS_G12V PIK3CG 58 51 Female -1.44 -4.25 0.36 1388.65 1.00 1012 57 50 1 FALSE 0.64
colorectal cancer KRAS_G12V PIK3CG 204 107 Sex:overall -0.27 -1.29 0.71 377.90 1.00 1995 196 99 8 FALSE 0.21
non-small cell lung cancer KRAS_G12V PIK3CG 169 180 Sex:overall 0.01 -1.33 1.21 1362.33 1.00 3376 160 171 9 FALSE 0.01
uterine cancer KRAS_G12V PIK3CG 58 51 Sex:overall -1.24 -5.75 3.12 1500.41 1.00 1012 57 50 1 FALSE 0.25
colorectal cancer KRAS_G12V MAP2K4 102 28 Female -2.44 -5.02 -0.45 25.08 1.12 922 101 27 1 TRUE 1.09
colorectal cancer KRAS_G12V MAP2K4 102 35 Male -2.62 -5.27 -0.64 32.42 1.09 1098 102 35 0 TRUE 1.15
colorectal cancer KRAS_G12V MAP2K4 204 63 Sex:overall -2.52 -5.11 -0.45 28.06 1.11 2020 203 62 1 TRUE 1.14
colorectal cancer KRAS_G12V EGFR 113 28 Female -0.83 -2.27 0.35 368.87 1.01 1016 111 26 2 TRUE 0.66
colorectal cancer KRAS_G12V EGFR 113 38 Male -0.96 -2.57 0.17 279.51 1.01 1217 112 37 1 TRUE 0.75
non-small cell lung cancer KRAS_G12V EGFR 118 724 Female -3.70 -5.53 -2.39 1611.30 1.00 1509 116 722 2 TRUE 5.45
non-small cell lung cancer KRAS_G12V EGFR 58 318 Male -4.14 -7.38 -2.29 1511.32 1.00 1283 58 318 0 TRUE 2.69
colorectal cancer KRAS_G12V EGFR 226 66 Sex:overall -0.89 -2.41 0.34 403.26 1.01 2233 223 63 3 TRUE 0.66
non-small cell lung cancer KRAS_G12V EGFR 176 1042 Sex:overall -3.87 -6.31 -1.96 1574.80 1.00 2792 174 1040 2 TRUE 3.43
colorectal cancer KRAS_G12V ARID1B 102 70 Female -1.33 -2.60 -0.26 1124.33 1.00 892 99 67 3 TRUE 1.63
colorectal cancer KRAS_G12V ARID1B 102 70 Male -1.50 -2.79 -0.43 1185.84 1.00 1074 101 69 1 TRUE 1.77
non-small cell lung cancer KRAS_G12V ARID1B 114 68 Female 0.05 -0.89 0.88 1297.29 1.00 1972 110 64 4 TRUE 0.04
non-small cell lung cancer KRAS_G12V ARID1B 56 43 Male 0.06 -0.92 1.02 1541.41 1.00 1456 54 41 2 TRUE 0.05
uterine cancer KRAS_G12V ARID1B 59 114 Female -0.28 -1.38 0.59 1276.80 1.00 966 54 109 5 TRUE 0.23
colorectal cancer KRAS_G12V ARID1B 204 140 Sex:overall -1.40 -2.75 -0.29 1099.14 1.00 1966 200 136 4 TRUE 1.55
non-small cell lung cancer KRAS_G12V ARID1B 170 111 Sex:overall 0.05 -1.08 1.06 1521.92 1.00 3428 164 105 6 TRUE 0.03
uterine cancer KRAS_G12V ARID1B 59 114 Sex:overall -0.21 -4.45 4.21 1132.12 1.00 966 54 109 5 TRUE 0.04
non-small cell lung cancer KRAS_G12V INSR 114 33 Female -1.40 -4.09 0.48 1297.57 1.00 1991 113 32 1 FALSE 0.62
non-small cell lung cancer KRAS_G12V INSR 55 22 Male -1.66 -4.93 0.41 1181.77 1.00 1469 55 22 0 FALSE 0.61
uterine cancer KRAS_G12V INSR 56 56 Female -1.53 -4.12 0.22 991.11 1.00 954 55 55 1 FALSE 0.75
non-small cell lung cancer KRAS_G12V INSR 169 55 Sex:overall -1.49 -4.34 0.57 1216.16 1.00 3460 168 54 1 FALSE 0.61
uterine cancer KRAS_G12V INSR 56 56 Sex:overall -1.30 -5.97 3.17 1104.39 1.00 954 55 55 1 FALSE 0.26
non-small cell lung cancer KRAS_G12V NKX2-1 114 34 Female 1.21 0.36 1.95 1608.79 1.00 2007 109 29 5 TRUE 2.49
non-small cell lung cancer KRAS_G12V NKX2-1 58 41 Male 1.42 0.59 2.20 1552.98 1.00 1464 52 35 6 TRUE 3.39
non-small cell lung cancer KRAS_G12V NKX2-1 172 75 Sex:overall 1.31 0.18 2.42 1428.65 1.00 3471 161 64 11 TRUE 1.73
colorectal cancer KRAS_G12V ARID5B 102 20 Female -1.37 -3.35 0.18 1357.79 1.00 930 101 19 1 FALSE 0.89
colorectal cancer KRAS_G12V ARID5B 102 48 Male -1.53 -3.40 -0.03 1379.58 1.00 1097 101 47 1 FALSE 1.08
uterine cancer KRAS_G12V ARID5B 58 81 Female -0.95 -2.78 0.28 355.79 1.01 988 56 79 2 FALSE 0.66
colorectal cancer KRAS_G12V ARID5B 204 68 Sex:overall -1.44 -3.57 0.37 1336.80 1.00 2027 202 66 2 FALSE 0.85
uterine cancer KRAS_G12V ARID5B 58 81 Sex:overall -0.79 -5.04 3.64 1375.53 1.00 988 56 79 2 FALSE 0.16
non-small cell lung cancer KRAS_G12V WT1 114 39 Female -0.26 -1.80 0.90 1406.57 1.00 1998 112 37 2 TRUE 0.16
non-small cell lung cancer KRAS_G12V WT1 55 31 Male -0.28 -1.88 1.01 1409.80 1.00 1467 54 30 1 TRUE 0.15
non-small cell lung cancer KRAS_G12V WT1 169 70 Sex:overall -0.27 -1.89 1.06 1305.47 1.00 3465 166 67 3 TRUE 0.14
non-small cell lung cancer KRAS_G12V MET 118 94 Female -0.34 -1.36 0.50 1024.94 1.00 2015 114 90 4 TRUE 0.33
non-small cell lung cancer KRAS_G12V MET 58 71 Male -0.37 -1.52 0.58 990.97 1.00 1487 56 69 2 TRUE 0.31
uterine cancer KRAS_G12V MET 66 59 Female -5.62 -14.41 -1.07 644.47 1.00 1118 66 59 0 TRUE 0.94
non-small cell lung cancer KRAS_G12V MET 176 165 Sex:overall -0.36 -1.52 0.62 1081.10 1.00 3502 170 159 6 TRUE 0.26
uterine cancer KRAS_G12V MET 66 59 Sex:overall -4.19 -11.30 2.60 1074.23 1.00 1118 66 59 0 TRUE 0.65
non-small cell lung cancer KRAS_G12V PMS1 114 29 Female 0.97 -0.05 1.84 1516.13 1.00 2009 110 25 4 TRUE 1.40
non-small cell lung cancer KRAS_G12V PMS1 55 23 Male 0.92 -0.24 1.92 1492.82 1.00 1474 53 21 2 TRUE 1.04
non-small cell lung cancer KRAS_G12V PMS1 169 52 Sex:overall 0.94 -0.33 1.98 1416.98 1.00 3483 163 46 6 TRUE 0.90
pancreatic cancer KRAS_G12V MEN1 183 36 Female -3.56 -6.07 -1.81 805.02 1.00 509 182 35 1 TRUE 2.85
pancreatic cancer KRAS_G12V MEN1 207 41 Male -3.67 -6.31 -1.92 790.52 1.00 563 207 41 0 TRUE 2.93
pancreatic cancer KRAS_G12V MEN1 390 77 Sex:overall -3.61 -6.11 -1.83 881.21 1.00 1072 389 76 1 TRUE 2.88
non-small cell lung cancer KRAS_G12V PIK3C3 114 40 Female 0.09 -1.14 1.11 1354.59 1.00 1986 111 37 3 FALSE 0.06
non-small cell lung cancer KRAS_G12V PIK3C3 55 36 Male -0.12 -1.66 1.00 1347.85 1.00 1455 54 35 1 FALSE 0.07
non-small cell lung cancer KRAS_G12V PIK3C3 169 76 Sex:overall -0.02 -1.62 1.28 1404.61 1.00 3441 165 72 4 FALSE 0.01
colorectal cancer KRAS_G12V BRAF 113 128 Female -2.20 -3.70 -1.10 1024.71 1.00 919 112 127 1 TRUE 3.24
colorectal cancer KRAS_G12V BRAF 113 125 Male -1.92 -3.15 -0.88 935.87 1.00 1134 110 122 3 TRUE 3.11
non-small cell lung cancer KRAS_G12V BRAF 118 113 Female -0.20 -1.07 0.55 1436.14 1.00 1989 113 108 5 TRUE 0.20
non-small cell lung cancer KRAS_G12V BRAF 58 80 Male -0.14 -1.08 0.70 1359.30 1.00 1475 55 77 3 TRUE 0.12
colorectal cancer KRAS_G12V BRAF 226 253 Sex:overall -2.04 -3.43 -0.88 1286.13 1.00 2053 222 249 4 TRUE 2.74
non-small cell lung cancer KRAS_G12V BRAF 176 193 Sex:overall -0.16 -1.25 0.78 1352.04 1.00 3464 168 185 8 TRUE 0.13
colorectal cancer KRAS_G12V B2M 95 69 Female -2.10 -3.85 -0.80 447.36 1.00 882 94 68 1 FALSE 2.12
colorectal cancer KRAS_G12V B2M 99 70 Male -2.09 -3.89 -0.78 419.50 1.01 1057 98 69 1 FALSE 2.12
colorectal cancer KRAS_G12V B2M 194 139 Sex:overall -2.08 -3.84 -0.72 463.79 1.00 1939 192 137 2 FALSE 1.98
colorectal cancer KRAS_G12V TGFBR1 95 14 Female -0.35 -1.86 0.93 1215.62 1.00 910 94 13 1 FALSE 0.20
colorectal cancer KRAS_G12V TGFBR1 99 37 Male -0.20 -1.47 0.82 1345.03 1.00 1074 96 34 3 FALSE 0.14
non-small cell lung cancer KRAS_G12V TGFBR1 114 36 Female -0.62 -2.62 0.88 1400.27 1.00 1986 113 35 1 FALSE 0.31
non-small cell lung cancer KRAS_G12V TGFBR1 55 15 Male -0.33 -2.43 1.43 1432.18 1.00 1476 54 14 1 FALSE 0.13
colorectal cancer KRAS_G12V TGFBR1 194 51 Sex:overall -0.29 -1.86 1.15 1424.99 1.00 1984 190 47 4 FALSE 0.15
non-small cell lung cancer KRAS_G12V TGFBR1 169 51 Sex:overall -0.47 -2.60 1.55 1533.28 1.00 3462 167 49 2 FALSE 0.18
colorectal cancer KRAS_G12V TET2 102 31 Female -1.73 -3.60 -0.23 353.17 1.01 923 101 30 1 TRUE 1.33
colorectal cancer KRAS_G12V TET2 102 60 Male -1.82 -3.61 -0.42 392.07 1.01 1085 101 59 1 TRUE 1.55
non-small cell lung cancer KRAS_G12V TET2 114 38 Female -0.68 -2.50 0.70 900.69 1.00 1998 112 36 2 TRUE 0.38
non-small cell lung cancer KRAS_G12V TET2 55 43 Male -1.29 -4.59 0.44 1295.86 1.00 1456 55 43 0 TRUE 0.49
uterine cancer KRAS_G12V TET2 58 66 Female -1.74 -4.39 0.08 1533.37 1.00 1000 57 65 1 TRUE 0.90
colorectal cancer KRAS_G12V TET2 204 91 Sex:overall -1.77 -3.62 -0.21 410.96 1.01 2008 202 89 2 TRUE 1.36
non-small cell lung cancer KRAS_G12V TET2 169 81 Sex:overall -0.94 -3.42 0.86 1337.57 1.00 3454 167 79 2 TRUE 0.42
uterine cancer KRAS_G12V TET2 58 66 Sex:overall -1.41 -5.74 3.78 1381.24 1.00 1000 57 65 1 TRUE 0.27
colorectal cancer KRAS_G12V PDGFRB 102 24 Female -2.21 -5.24 -0.29 1143.13 1.00 924 102 24 0 TRUE 1.05
colorectal cancer KRAS_G12V PDGFRB 102 28 Male -1.98 -4.69 -0.06 1005.88 1.00 1105 101 27 1 TRUE 1.05
non-small cell lung cancer KRAS_G12V PDGFRB 115 54 Female 0.42 -0.57 1.25 1473.14 1.00 1988 111 50 4 TRUE 0.44
non-small cell lung cancer KRAS_G12V PDGFRB 55 38 Male 0.55 -0.48 1.50 1565.25 1.00 1463 52 35 3 TRUE 0.53
colorectal cancer KRAS_G12V PDGFRB 204 52 Sex:overall -2.05 -4.77 -0.11 1111.93 1.00 2029 203 51 1 TRUE 1.03
non-small cell lung cancer KRAS_G12V PDGFRB 170 92 Sex:overall 0.49 -0.68 1.61 1373.58 1.00 3451 163 85 7 TRUE 0.39
colorectal cancer KRAS_G12V CARD11 102 49 Female -0.83 -2.03 0.25 410.13 1.01 905 98 45 4 FALSE 0.83
colorectal cancer KRAS_G12V CARD11 102 79 Male -1.32 -2.84 -0.27 648.50 1.00 1064 101 78 1 FALSE 1.30
non-small cell lung cancer KRAS_G12V CARD11 114 71 Female -0.73 -2.08 0.35 1214.17 1.00 1968 111 68 3 FALSE 0.63
non-small cell lung cancer KRAS_G12V CARD11 55 59 Male -1.32 -4.04 0.14 1208.48 1.00 1440 55 59 0 FALSE 0.60
uterine cancer KRAS_G12V CARD11 58 55 Female -0.64 -2.52 0.67 1447.17 1.00 1006 56 53 2 FALSE 0.36
colorectal cancer KRAS_G12V CARD11 204 128 Sex:overall -1.05 -2.42 0.26 788.68 1.00 1969 199 123 5 FALSE 0.88
non-small cell lung cancer KRAS_G12V CARD11 169 130 Sex:overall -1.02 -2.94 0.36 1209.75 1.00 3408 166 127 3 FALSE 0.61
uterine cancer KRAS_G12V CARD11 58 55 Sex:overall -0.45 -4.81 4.02 1509.40 1.00 1006 56 53 2 FALSE 0.08
colorectal cancer KRAS_G12V DNMT3A 102 24 Female -1.25 -3.06 0.14 1112.36 1.00 929 101 23 1 TRUE 0.91
colorectal cancer KRAS_G12V DNMT3A 102 32 Male -1.25 -3.11 0.14 1174.31 1.00 1103 101 31 1 TRUE 0.90
non-small cell lung cancer KRAS_G12V DNMT3A 114 49 Female 0.22 -0.91 1.16 1305.97 1.00 1988 111 46 3 TRUE 0.17
non-small cell lung cancer KRAS_G12V DNMT3A 55 28 Male 0.33 -1.00 1.48 1243.59 1.00 1469 53 26 2 TRUE 0.22
colorectal cancer KRAS_G12V DNMT3A 204 56 Sex:overall -1.25 -3.16 0.19 1150.31 1.00 2032 202 54 2 TRUE 0.86
non-small cell lung cancer KRAS_G12V DNMT3A 169 77 Sex:overall 0.26 -1.03 1.44 1287.15 1.00 3457 164 72 5 TRUE 0.17
colorectal cancer KRAS_G12V MSH6 102 43 Female -1.30 -2.76 -0.10 1081.92 1.00 912 100 41 2 TRUE 1.33
colorectal cancer KRAS_G12V MSH6 102 57 Male -1.41 -2.98 -0.26 1206.48 1.00 1089 101 56 1 TRUE 1.40
uterine cancer KRAS_G12V MSH6 58 90 Female -0.25 -1.46 0.74 1287.57 1.00 991 54 86 4 TRUE 0.18
colorectal cancer KRAS_G12V MSH6 204 100 Sex:overall -1.36 -2.82 -0.16 1123.92 1.00 2001 201 97 3 TRUE 1.33
uterine cancer KRAS_G12V MSH6 58 90 Sex:overall -0.28 -4.87 3.87 1468.67 1.00 991 54 86 4 TRUE 0.05
non-small cell lung cancer KRAS_G12V MAX 114 35 Female 0.89 -0.09 1.78 1299.39 1.00 1992 109 30 5 FALSE 1.20
non-small cell lung cancer KRAS_G12V MAX 55 20 Male 0.66 -0.65 1.80 1398.29 1.00 1471 54 19 1 FALSE 0.50
non-small cell lung cancer KRAS_G12V MAX 169 55 Sex:overall 0.75 -0.67 1.91 1321.09 1.00 3463 163 49 6 FALSE 0.59
non-small cell lung cancer KRAS_G12V INPP4B 114 60 Female 0.18 -0.87 1.03 1597.21 1.00 1981 109 55 5 FALSE 0.15
non-small cell lung cancer KRAS_G12V INPP4B 55 66 Male -0.42 -2.24 0.70 1420.80 1.00 1438 54 65 1 FALSE 0.25
non-small cell lung cancer KRAS_G12V INPP4B 169 126 Sex:overall -0.12 -1.76 1.15 1514.46 1.00 3419 163 120 6 FALSE 0.06
non-small cell lung cancer KRAS_G12V NFE2L2 114 52 Female -0.51 -1.94 0.58 1452.96 1.00 1987 112 50 2 FALSE 0.38
non-small cell lung cancer KRAS_G12V NFE2L2 55 72 Male -0.46 -1.77 0.66 1439.33 1.00 1434 53 70 2 FALSE 0.32
non-small cell lung cancer KRAS_G12V NFE2L2 169 124 Sex:overall -0.47 -2.08 0.95 1427.61 1.00 3421 165 120 4 FALSE 0.27
uterine cancer KRAS_G12V SPOP 58 58 Female -1.57 -4.30 0.23 1262.78 1.00 996 57 57 1 FALSE 0.75
uterine cancer KRAS_G12V SPOP 58 58 Sex:overall -1.35 -6.16 4.44 1480.48 1.00 996 57 57 1 FALSE 0.25
colorectal cancer KRAS_G12V SOX9 102 125 Female 0.14 -0.44 0.61 636.98 1.01 845 91 114 11 FALSE 0.22
colorectal cancer KRAS_G12V SOX9 104 139 Male 0.34 -0.11 0.84 1062.36 1.00 1022 86 121 18 FALSE 0.76
colorectal cancer KRAS_G12V SOX9 206 264 Sex:overall 0.25 -0.38 0.90 1016.23 1.00 1867 177 235 29 FALSE 0.37
colorectal cancer KRAS_G12V ETV1 95 23 Female -1.34 -3.79 0.19 1007.21 1.00 900 95 23 0 TRUE 0.67
colorectal cancer KRAS_G12V ETV1 99 29 Male -0.97 -2.71 0.41 1172.26 1.00 1078 97 27 2 TRUE 0.63
colorectal cancer KRAS_G12V ETV1 194 52 Sex:overall -1.16 -3.34 0.36 1291.37 1.00 1978 192 50 2 TRUE 0.63
colorectal cancer KRAS_G12V ARAF 102 30 Female -1.74 -5.40 -0.06 958.07 1.00 922 102 30 0 FALSE 0.67
colorectal cancer KRAS_G12V ARAF 103 25 Male -1.04 -2.85 0.53 634.66 1.01 1109 101 23 2 FALSE 0.65
non-small cell lung cancer KRAS_G12V ARAF 114 55 Female -0.76 -2.66 0.59 1402.81 1.00 1989 112 53 2 FALSE 0.44
non-small cell lung cancer KRAS_G12V ARAF 55 14 Male -1.39 -5.47 0.83 1261.68 1.00 1481 55 14 0 FALSE 0.42
colorectal cancer KRAS_G12V ARAF 205 55 Sex:overall -1.35 -3.70 0.37 1083.92 1.00 2031 203 53 2 FALSE 0.69
non-small cell lung cancer KRAS_G12V ARAF 169 69 Sex:overall -1.05 -3.92 1.14 1303.72 1.00 3470 167 67 2 FALSE 0.39
non-small cell lung cancer KRAS_G12V JAK2 118 33 Female -0.29 -1.86 0.87 1345.95 1.00 2065 116 31 2 TRUE 0.16
non-small cell lung cancer KRAS_G12V JAK2 58 45 Male -0.48 -2.20 0.85 1344.18 1.00 1509 57 44 1 TRUE 0.26
non-small cell lung cancer KRAS_G12V JAK2 176 78 Sex:overall -0.39 -2.24 1.07 1448.82 1.00 3574 173 75 3 TRUE 0.18
colorectal cancer KRAS_G12V SMAD2 103 43 Female 0.53 -0.19 1.16 786.26 1.00 914 97 37 6 TRUE 0.85
colorectal cancer KRAS_G12V SMAD2 102 59 Male 0.62 -0.05 1.24 886.82 1.00 1089 93 50 9 TRUE 1.20
colorectal cancer KRAS_G12V SMAD2 205 102 Sex:overall 0.57 -0.20 1.28 783.75 1.00 2003 190 87 15 TRUE 0.85
non-small cell lung cancer KRAS_G12V TP63 114 34 Female -0.21 -1.76 1.01 1297.35 1.00 1991 112 32 2 FALSE 0.12
non-small cell lung cancer KRAS_G12V TP63 55 38 Male -0.34 -2.04 0.96 1430.10 1.00 1453 54 37 1 FALSE 0.19
non-small cell lung cancer KRAS_G12V TP63 169 72 Sex:overall -0.29 -2.05 1.12 1398.93 1.00 3444 166 69 3 FALSE 0.15
colorectal cancer KRAS_G12V JUN 95 32 Female -2.29 -5.55 -0.38 665.48 1.00 892 95 32 0 FALSE 1.00
colorectal cancer KRAS_G12V JUN 99 21 Male -1.80 -4.62 0.21 1006.98 1.00 1084 98 20 1 FALSE 0.89
colorectal cancer KRAS_G12V JUN 194 53 Sex:overall -2.02 -5.15 -0.01 709.18 1.01 1976 193 52 1 FALSE 0.96
colorectal cancer KRAS_G12V DNMT3B 95 25 Female -0.25 -1.46 0.75 903.56 1.00 901 93 23 2 FALSE 0.19
colorectal cancer KRAS_G12V DNMT3B 100 39 Male -0.25 -1.40 0.69 775.06 1.00 1071 97 36 3 FALSE 0.20
colorectal cancer KRAS_G12V DNMT3B 195 64 Sex:overall -0.24 -1.50 0.78 881.02 1.00 1972 190 59 5 FALSE 0.16
non-small cell lung cancer KRAS_G12V MYOD1 114 29 Female 0.38 -0.80 1.44 1250.41 1.00 1999 111 26 3 FALSE 0.29
non-small cell lung cancer KRAS_G12V MYOD1 55 29 Male 0.17 -1.29 1.33 1363.17 1.00 1462 54 28 1 FALSE 0.10
non-small cell lung cancer KRAS_G12V MYOD1 169 58 Sex:overall 0.25 -1.34 1.51 1350.95 1.00 3461 165 54 4 FALSE 0.14
colorectal cancer KRAS_G12V FGFR1 113 21 Female -1.93 -4.64 -0.14 1352.87 1.00 1020 112 20 1 TRUE 1.01
colorectal cancer KRAS_G12V FGFR1 113 30 Male -2.18 -5.33 -0.32 1222.38 1.00 1225 113 30 0 TRUE 0.98
colorectal cancer KRAS_G12V FGFR1 226 51 Sex:overall -2.03 -4.88 -0.10 1316.57 1.00 2245 225 50 1 TRUE 0.99
colorectal cancer KRAS_G12V MITF 102 22 Female -1.95 -4.62 -0.13 479.52 1.00 927 101 21 1 FALSE 1.01
colorectal cancer KRAS_G12V MITF 102 30 Male -2.20 -5.36 -0.20 668.67 1.00 1102 102 30 0 FALSE 0.90
colorectal cancer KRAS_G12V MITF 204 52 Sex:overall -2.05 -4.88 -0.19 538.45 1.00 2029 203 51 1 FALSE 1.00
non-small cell lung cancer KRAS_G12V BTK 114 47 Female -0.11 -1.59 1.02 1398.90 1.00 1990 111 44 3 TRUE 0.06
non-small cell lung cancer KRAS_G12V BTK 55 13 Male -0.87 -4.53 1.16 1243.93 1.00 1482 55 13 0 TRUE 0.25
non-small cell lung cancer KRAS_G12V BTK 169 60 Sex:overall -0.47 -3.20 1.49 1459.79 1.00 3472 166 57 3 TRUE 0.16
colorectal cancer KRAS_G12V SH2B3 93 18 Female -5.31 -11.84 -1.12 762.31 1.00 845 93 18 0 FALSE 1.28
colorectal cancer KRAS_G12V SH2B3 95 38 Male -5.36 -11.81 -1.27 757.36 1.00 1004 95 38 0 FALSE 1.30
colorectal cancer KRAS_G12V SH2B3 188 56 Sex:overall -5.26 -11.63 -1.12 700.96 1.00 1849 188 56 0 FALSE 1.29
colorectal cancer KRAS_G12V GLI1 93 32 Female -1.98 -4.60 -0.45 1258.28 1.00 833 93 32 0 FALSE 1.10
colorectal cancer KRAS_G12V GLI1 95 55 Male -1.58 -3.27 -0.27 1021.40 1.00 990 93 53 2 FALSE 1.42
non-small cell lung cancer KRAS_G12V GLI1 106 56 Female 0.64 -0.23 1.38 1347.32 1.00 1790 100 50 6 FALSE 0.93
non-small cell lung cancer KRAS_G12V GLI1 51 50 Male 0.55 -0.40 1.38 1495.95 1.00 1297 48 47 3 FALSE 0.62
uterine cancer KRAS_G12V GLI1 53 53 Female -1.54 -4.25 0.29 612.41 1.00 903 52 52 1 FALSE 0.71
colorectal cancer KRAS_G12V GLI1 188 87 Sex:overall -1.72 -3.79 -0.18 1212.16 1.00 1823 186 85 2 FALSE 1.13
non-small cell lung cancer KRAS_G12V GLI1 157 106 Sex:overall 0.61 -0.50 1.64 1373.80 1.00 3087 148 97 9 FALSE 0.59
uterine cancer KRAS_G12V GLI1 53 53 Sex:overall -1.24 -5.69 3.45 1177.60 1.00 903 52 52 1 FALSE 0.24
colorectal cancer KRAS_G12V ZFHX3 94 96 Female -1.29 -2.18 -0.46 1099.30 1.00 795 91 93 3 FALSE 2.64
colorectal cancer KRAS_G12V ZFHX3 96 130 Male -1.27 -2.11 -0.46 1147.88 1.00 951 92 126 4 FALSE 2.68
non-small cell lung cancer KRAS_G12V ZFHX3 107 90 Female 0.35 -0.41 1.00 350.72 1.01 1759 99 82 8 FALSE 0.47
non-small cell lung cancer KRAS_G12V ZFHX3 51 74 Male 0.05 -1.14 1.04 208.71 1.02 1269 49 72 2 FALSE 0.03
uterine cancer KRAS_G12V ZFHX3 54 215 Female -0.42 -1.28 0.33 1061.42 1.00 816 46 207 8 FALSE 0.53
colorectal cancer KRAS_G12V ZFHX3 190 226 Sex:overall -1.28 -2.18 -0.40 1141.55 1.00 1746 183 219 7 FALSE 2.33
non-small cell lung cancer KRAS_G12V ZFHX3 158 164 Sex:overall 0.22 -1.04 1.22 595.02 1.01 3028 148 154 10 FALSE 0.15
uterine cancer KRAS_G12V ZFHX3 54 215 Sex:overall -0.33 -4.54 4.00 1474.74 1.00 816 46 207 8 FALSE 0.06
colorectal cancer KRAS_G12V MST1R 86 28 Female -2.20 -4.71 -0.29 923.95 1.00 816 85 27 1 FALSE 1.35
colorectal cancer KRAS_G12V MST1R 92 45 Male -2.47 -5.33 -0.46 704.73 1.00 969 92 45 0 FALSE 1.26
colorectal cancer KRAS_G12V MST1R 178 73 Sex:overall -2.29 -4.86 -0.31 829.27 1.00 1785 177 72 1 FALSE 1.33
colorectal cancer KRAS_G12V MGA 94 50 Female -0.29 -1.09 0.41 1171.98 1.00 821 90 46 4 FALSE 0.33
colorectal cancer KRAS_G12V MGA 95 73 Male -0.28 -1.09 0.43 1025.46 1.00 979 90 68 5 FALSE 0.32
non-small cell lung cancer KRAS_G12V MGA 106 117 Female 0.51 -0.17 1.10 1318.05 1.00 1754 95 106 11 FALSE 0.95
non-small cell lung cancer KRAS_G12V MGA 51 80 Male 0.27 -0.67 1.02 1432.80 1.00 1263 48 77 3 FALSE 0.28
uterine cancer KRAS_G12V MGA 53 115 Female -1.40 -3.33 -0.14 1221.38 1.00 879 51 113 2 FALSE 1.13
colorectal cancer KRAS_G12V MGA 189 123 Sex:overall -0.27 -1.20 0.55 1070.30 1.00 1800 180 114 9 FALSE 0.26
non-small cell lung cancer KRAS_G12V MGA 157 197 Sex:overall 0.38 -0.59 1.27 1171.05 1.00 3017 143 183 14 FALSE 0.38
uterine cancer KRAS_G12V MGA 53 115 Sex:overall -1.23 -5.34 3.56 1200.71 1.00 879 51 113 2 FALSE 0.26
colorectal cancer KRAS_G12V TCF3 87 31 Female -0.87 -2.30 0.24 1154.86 1.00 811 85 29 2 FALSE 0.72
colorectal cancer KRAS_G12V TCF3 92 37 Male -0.97 -2.60 0.16 1095.81 1.00 973 91 36 1 FALSE 0.78
colorectal cancer KRAS_G12V TCF3 179 68 Sex:overall -0.91 -2.47 0.29 1205.46 1.00 1784 176 65 3 FALSE 0.69
colorectal cancer KRAS_G12V KMT2B 55 87 Female -1.62 -3.10 -0.64 1061.93 1.00 440 54 86 1 FALSE 2.05
colorectal cancer KRAS_G12V KMT2B 53 95 Male -1.30 -2.36 -0.36 928.10 1.00 539 49 91 4 FALSE 2.03
non-small cell lung cancer KRAS_G12V KMT2B 63 33 Female -0.39 -2.27 0.92 59.56 1.05 1032 61 31 2 FALSE 0.20
non-small cell lung cancer KRAS_G12V KMT2B 28 38 Male -0.52 -2.31 0.87 74.05 1.05 709 27 37 1 FALSE 0.26
colorectal cancer KRAS_G12V KMT2B 108 182 Sex:overall -1.45 -2.73 -0.32 1166.15 1.00 979 103 177 5 FALSE 1.69
non-small cell lung cancer KRAS_G12V KMT2B 91 71 Sex:overall -0.44 -2.29 1.07 72.22 1.04 1741 88 68 3 FALSE 0.20
colorectal cancer KRAS_G12V TCF7L2 95 124 Female 0.08 -0.41 0.61 1419.75 1.00 761 80 109 15 FALSE 0.12
colorectal cancer KRAS_G12V TCF7L2 97 175 Male -0.11 -0.67 0.37 1340.23 1.00 889 85 163 12 FALSE 0.18
colorectal cancer KRAS_G12V TCF7L2 192 299 Sex:overall -0.04 -0.74 0.60 1524.27 1.00 1650 165 272 27 FALSE 0.04
colorectal cancer KRAS_G12V MSH3 55 46 Female -2.83 -5.77 -0.86 927.00 1.00 458 55 46 0 FALSE 1.52
colorectal cancer KRAS_G12V MSH3 51 43 Male -2.52 -5.03 -0.68 522.47 1.00 559 50 42 1 FALSE 1.57
colorectal cancer KRAS_G12V MSH3 106 89 Sex:overall -2.65 -5.23 -0.80 692.56 1.00 1017 105 88 1 FALSE 1.59
colorectal cancer KRAS_G12V ANKRD11 86 56 Female -1.41 -2.86 -0.07 988.95 1.00 793 83 53 3 FALSE 1.30
colorectal cancer KRAS_G12V ANKRD11 92 90 Male -2.34 -5.72 -0.75 1230.10 1.00 943 92 90 0 FALSE 1.11
non-small cell lung cancer KRAS_G12V ANKRD11 106 40 Female -0.81 -2.58 0.52 1116.17 1.00 1791 105 39 1 FALSE 0.49
non-small cell lung cancer KRAS_G12V ANKRD11 51 32 Male -0.68 -2.52 0.77 1039.92 1.00 1303 50 31 1 FALSE 0.37
uterine cancer KRAS_G12V ANKRD11 51 90 Female -0.33 -1.51 0.68 1399.44 1.00 828 47 86 4 FALSE 0.25
colorectal cancer KRAS_G12V ANKRD11 178 146 Sex:overall -1.83 -4.05 -0.12 1304.66 1.00 1736 175 143 3 FALSE 1.14
non-small cell lung cancer KRAS_G12V ANKRD11 157 72 Sex:overall -0.74 -2.61 0.71 1040.99 1.00 3094 155 70 2 FALSE 0.40
uterine cancer KRAS_G12V ANKRD11 51 90 Sex:overall -0.37 -4.86 3.91 1360.31 1.00 828 47 86 4 FALSE 0.07
colorectal cancer KRAS_G12V PGR 86 30 Female -1.35 -3.20 0.08 689.57 1.01 808 85 29 1 FALSE 0.96
colorectal cancer KRAS_G12V PGR 92 33 Male -1.34 -3.19 0.08 730.17 1.00 981 91 32 1 FALSE 0.93
non-small cell lung cancer KRAS_G12V PGR 106 44 Female -5.30 -12.22 -1.32 964.94 1.00 1783 106 44 0 FALSE 1.17
non-small cell lung cancer KRAS_G12V PGR 51 43 Male -5.26 -11.96 -1.16 1072.98 1.01 1293 51 43 0 FALSE 1.17
uterine cancer KRAS_G12V PGR 51 56 Female -1.63 -4.54 0.16 978.52 1.00 841 50 55 1 FALSE 0.73
colorectal cancer KRAS_G12V PGR 178 63 Sex:overall -1.32 -3.26 0.17 755.06 1.01 1789 176 61 2 FALSE 0.87
non-small cell lung cancer KRAS_G12V PGR 157 87 Sex:overall -5.21 -11.79 -1.12 1077.41 1.01 3076 157 87 0 FALSE 1.19
uterine cancer KRAS_G12V PGR 51 56 Sex:overall -1.38 -5.78 3.27 1430.51 1.00 841 50 55 1 FALSE 0.28
colorectal cancer KRAS_G12V PLCG2 86 31 Female -1.63 -3.42 -0.16 1109.41 1.00 808 85 30 1 FALSE 1.28
colorectal cancer KRAS_G12V PLCG2 92 54 Male -1.68 -3.51 -0.34 1186.77 1.00 961 91 53 1 FALSE 1.43
non-small cell lung cancer KRAS_G12V PLCG2 106 31 Female -1.41 -3.99 0.32 832.34 1.00 1800 105 30 1 FALSE 0.70
non-small cell lung cancer KRAS_G12V PLCG2 51 31 Male -1.69 -4.88 0.23 641.16 1.00 1306 51 31 0 FALSE 0.62
uterine cancer KRAS_G12V PLCG2 51 57 Female -5.70 -14.89 -0.94 1202.41 1.00 849 51 57 0 FALSE 0.95
colorectal cancer KRAS_G12V PLCG2 178 85 Sex:overall -1.65 -3.53 -0.17 1147.63 1.00 1769 176 83 2 FALSE 1.22
non-small cell lung cancer KRAS_G12V PLCG2 157 62 Sex:overall -1.55 -4.42 0.38 794.81 1.00 3106 156 61 1 FALSE 0.67
uterine cancer KRAS_G12V PLCG2 51 57 Sex:overall -4.31 -11.54 2.64 1249.88 1.00 849 51 57 0 FALSE 0.68
colorectal cancer KRAS_G12V POLD1 93 49 Female -1.18 -2.69 -0.15 494.63 1.00 826 91 47 2 TRUE 1.31
colorectal cancer KRAS_G12V POLD1 95 63 Male -1.19 -2.67 -0.20 546.89 1.00 992 93 61 2 TRUE 1.33
non-small cell lung cancer KRAS_G12V POLD1 106 31 Female -0.23 -1.85 1.09 1209.35 1.00 1809 105 30 1 TRUE 0.12
non-small cell lung cancer KRAS_G12V POLD1 51 27 Male 0.12 -1.41 1.42 1188.42 1.00 1314 49 25 2 TRUE 0.06
colorectal cancer KRAS_G12V POLD1 188 112 Sex:overall -1.17 -2.69 -0.09 555.00 1.00 1818 184 108 4 TRUE 1.15
non-small cell lung cancer KRAS_G12V POLD1 157 58 Sex:overall -0.05 -1.85 1.42 1426.44 1.00 3123 154 55 3 TRUE 0.02
colorectal cancer KRAS_G12V INHBA 93 24 Female 0.13 -1.00 0.95 260.93 1.01 841 91 22 2 FALSE 0.10
colorectal cancer KRAS_G12V INHBA 95 30 Male 0.25 -0.73 1.10 361.23 1.01 1011 91 26 4 FALSE 0.23
non-small cell lung cancer KRAS_G12V INHBA 106 46 Female -0.87 -2.78 0.45 1233.94 1.00 1798 104 44 2 FALSE 0.55
non-small cell lung cancer KRAS_G12V INHBA 51 41 Male -1.40 -4.85 0.29 1162.49 1.00 1300 51 41 0 FALSE 0.55
colorectal cancer KRAS_G12V INHBA 188 54 Sex:overall 0.18 -0.91 1.03 409.71 1.01 1852 182 48 6 FALSE 0.14
non-small cell lung cancer KRAS_G12V INHBA 157 87 Sex:overall -1.10 -3.62 0.49 1354.49 1.00 3098 155 85 2 FALSE 0.54
colorectal cancer KRAS_G12V PREX2 55 31 Female -1.29 -2.93 -0.04 1250.39 1.00 472 54 30 1 FALSE 1.08
colorectal cancer KRAS_G12V PREX2 51 60 Male -1.21 -2.68 -0.10 1128.86 1.00 547 49 58 2 FALSE 1.14
non-small cell lung cancer KRAS_G12V PREX2 62 62 Female 0.06 -1.01 1.03 741.75 1.00 1011 57 57 5 FALSE 0.04
non-small cell lung cancer KRAS_G12V PREX2 28 43 Male -0.83 -4.47 0.72 1075.62 1.01 705 28 43 0 FALSE 0.26
colorectal cancer KRAS_G12V PREX2 106 91 Sex:overall -1.24 -3.03 0.18 1208.37 1.00 1019 103 88 3 FALSE 0.92
non-small cell lung cancer KRAS_G12V PREX2 90 105 Sex:overall -0.35 -2.62 1.03 1299.81 1.00 1716 85 100 5 FALSE 0.15
colorectal cancer KRAS_G12V AMER1 102 85 Female 0.38 -0.19 0.91 1319.49 1.00 882 91 74 11 FALSE 0.75
colorectal cancer KRAS_G12V AMER1 102 84 Male 0.38 -0.18 0.91 1277.34 1.00 1063 92 74 10 FALSE 0.76
non-small cell lung cancer KRAS_G12V AMER1 115 104 Female 0.28 -0.49 0.98 1445.54 1.00 1952 108 97 7 FALSE 0.33
non-small cell lung cancer KRAS_G12V AMER1 55 45 Male 0.42 -0.58 1.40 1541.28 1.00 1457 52 42 3 FALSE 0.39
uterine cancer KRAS_G12V AMER1 58 56 Female -0.14 -1.57 1.00 1301.94 1.00 1015 55 53 3 FALSE 0.08
colorectal cancer KRAS_G12V AMER1 204 169 Sex:overall 0.38 -0.27 0.99 1450.59 1.00 1945 183 148 21 FALSE 0.58
non-small cell lung cancer KRAS_G12V AMER1 170 149 Sex:overall 0.34 -0.83 1.46 1384.24 1.00 3409 160 139 10 FALSE 0.24
uterine cancer KRAS_G12V AMER1 58 56 Sex:overall -0.06 -4.36 4.78 1359.24 1.00 1015 55 53 3 FALSE 0.01
colorectal cancer KRAS_G12V HLA-A 86 26 Female -2.21 -5.24 -0.30 403.70 1.00 814 86 26 0 FALSE 0.98
colorectal cancer KRAS_G12V HLA-A 92 25 Male -2.00 -4.67 -0.10 233.44 1.01 987 91 24 1 FALSE 1.00
colorectal cancer KRAS_G12V HLA-A 178 51 Sex:overall -2.09 -4.74 -0.16 286.71 1.00 1801 177 50 1 FALSE 1.01
colorectal cancer KRAS_G12V EPHA7 93 39 Female -0.36 -1.38 0.61 550.19 1.01 831 89 35 4 FALSE 0.33
colorectal cancer KRAS_G12V EPHA7 95 51 Male -0.54 -1.70 0.38 844.16 1.00 995 93 49 2 FALSE 0.51
non-small cell lung cancer KRAS_G12V EPHA7 106 67 Female -0.06 -1.20 0.93 1355.30 1.00 1778 101 62 5 FALSE 0.04
non-small cell lung cancer KRAS_G12V EPHA7 51 62 Male -1.18 -5.14 0.41 1099.58 1.00 1281 51 62 0 FALSE 0.39
colorectal cancer KRAS_G12V EPHA7 188 90 Sex:overall -0.45 -1.59 0.56 585.77 1.00 1826 182 84 6 FALSE 0.38
non-small cell lung cancer KRAS_G12V EPHA7 157 129 Sex:overall -0.59 -2.94 1.00 1306.24 1.00 3059 152 124 5 FALSE 0.25
colorectal cancer KRAS_G12V NCOA3 93 21 Female -0.63 -2.05 0.61 1289.69 1.00 844 91 19 2 TRUE 0.45
colorectal cancer KRAS_G12V NCOA3 95 35 Male -0.80 -2.37 0.41 1266.64 1.00 1005 94 34 1 TRUE 0.60
colorectal cancer KRAS_G12V NCOA3 188 56 Sex:overall -0.70 -2.25 0.59 1445.59 1.00 1849 185 53 3 TRUE 0.46
non-small cell lung cancer KRAS_G12V DROSHA 62 26 Female 0.04 -1.80 1.25 1482.37 1.00 1023 61 25 1 FALSE 0.02
non-small cell lung cancer KRAS_G12V DROSHA 28 28 Male 0.65 -0.79 1.88 1322.54 1.00 716 25 25 3 FALSE 0.49
non-small cell lung cancer KRAS_G12V DROSHA 90 54 Sex:overall 0.33 -1.51 1.86 1305.14 1.00 1739 86 50 4 FALSE 0.16
colorectal cancer KRAS_G12V SLX4 48 20 Female -0.89 -2.69 0.64 1216.76 1.00 453 46 18 2 FALSE 0.55
colorectal cancer KRAS_G12V SLX4 48 34 Male -1.54 -4.53 0.02 197.84 1.02 538 48 34 0 FALSE 0.62
colorectal cancer KRAS_G12V SLX4 96 54 Sex:overall -1.19 -3.47 0.45 589.35 1.01 991 94 52 2 FALSE 0.64
colorectal cancer KRAS_G12V INPPL1 49 22 Female -0.07 -1.37 1.15 1506.26 1.00 456 46 19 3 FALSE 0.04
colorectal cancer KRAS_G12V INPPL1 48 51 Male -0.55 -1.86 0.53 1384.00 1.00 530 46 49 2 FALSE 0.43
colorectal cancer KRAS_G12V INPPL1 97 73 Sex:overall -0.31 -1.77 1.14 1146.69 1.00 986 92 68 5 FALSE 0.17
colorectal cancer KRAS_G13D SPEN 87 55 Female -0.93 -2.63 0.15 865.38 1.00 921 86 54 1 FALSE 0.66
colorectal cancer KRAS_G13D SPEN 89 100 Male -0.15 -0.95 0.59 1048.78 1.00 1082 81 92 8 FALSE 0.15
colorectal cancer KRAS_G13D SPEN 176 155 Sex:overall -0.52 -2.22 0.74 1520.84 1.00 2003 167 146 9 FALSE 0.32
colorectal cancer KRAS_G13D KMT2C 84 68 Female -0.02 -0.84 0.64 1213.92 1.00 882 79 63 5 FALSE 0.02
colorectal cancer KRAS_G13D KMT2C 91 130 Male 0.17 -0.40 0.74 1369.87 1.00 1037 79 118 12 FALSE 0.24
colorectal cancer KRAS_G13D KMT2C 175 198 Sex:overall 0.09 -0.88 1.02 1381.09 1.00 1919 158 181 17 FALSE 0.07
colorectal cancer KRAS_G13D TP53 100 796 Female -0.38 -0.71 -0.04 1227.89 1.00 374 42 738 58 TRUE 1.60
colorectal cancer KRAS_G13D TP53 97 923 Male -0.45 -0.79 -0.12 840.66 1.00 459 45 871 52 TRUE 2.09
colorectal cancer KRAS_G13D TP53 197 1719 Sex:overall -0.42 -0.82 -0.01 1051.18 1.00 833 87 1609 110 TRUE 1.21
colorectal cancer KRAS_G13D ATRX 89 73 Female -0.15 -1.04 0.61 1351.27 1.00 905 84 68 5 TRUE 0.13
colorectal cancer KRAS_G13D ATRX 90 46 Male 0.16 -0.71 1.05 1424.99 1.00 1111 85 41 5 TRUE 0.14
colorectal cancer KRAS_G13D ATRX 179 119 Sex:overall 0.02 -1.14 1.19 1414.90 1.00 2016 169 109 10 TRUE 0.01
colorectal cancer KRAS_G13D ATR 87 30 Female -0.45 -2.38 0.77 1307.97 1.00 936 86 29 1 FALSE 0.23
colorectal cancer KRAS_G13D ATR 90 84 Male 0.59 -0.14 1.25 1590.14 1.00 1099 79 73 11 FALSE 1.04
colorectal cancer KRAS_G13D ATR 177 114 Sex:overall 0.09 -1.81 1.62 1266.91 1.00 2035 165 102 12 FALSE 0.04
colorectal cancer KRAS_G13D PDGFRA 94 28 Female 0.64 -0.37 1.42 1105.13 1.00 1033 91 25 3 TRUE 0.82
colorectal cancer KRAS_G13D PDGFRA 97 32 Male 0.81 -0.02 1.62 1150.84 1.00 1245 91 26 6 TRUE 1.34
colorectal cancer KRAS_G13D PDGFRA 191 60 Sex:overall 0.72 -0.20 1.53 1137.95 1.00 2278 182 51 9 TRUE 0.97
colorectal cancer KRAS_G13D FBXW7 96 137 Female 0.62 0.08 1.07 1474.62 1.00 952 80 121 16 TRUE 1.82
colorectal cancer KRAS_G13D FBXW7 97 202 Male 0.91 0.48 1.34 419.39 1.01 1121 67 172 30 TRUE 4.18
colorectal cancer KRAS_G13D FBXW7 193 339 Sex:overall 0.77 -0.01 1.55 1601.73 1.00 2073 147 293 46 TRUE 1.21
colorectal cancer KRAS_G13D MAP3K1 87 39 Female 0.28 -0.56 0.99 1325.86 1.00 934 82 34 5 FALSE 0.32
colorectal cancer KRAS_G13D MAP3K1 88 53 Male 0.20 -0.68 0.96 1134.37 1.00 1102 84 49 4 FALSE 0.20
colorectal cancer KRAS_G13D MAP3K1 175 92 Sex:overall 0.24 -0.71 1.02 1237.38 1.00 2036 166 83 9 FALSE 0.22
colorectal cancer KRAS_G13D NSD1 87 35 Female -0.28 -2.20 0.79 1315.17 1.00 934 86 34 1 FALSE 0.15
colorectal cancer KRAS_G13D NSD1 89 51 Male 0.59 -0.24 1.40 1072.07 1.00 1110 81 43 8 FALSE 0.78
colorectal cancer KRAS_G13D NSD1 176 86 Sex:overall 0.14 -1.51 1.41 1449.87 1.00 2044 167 77 9 FALSE 0.07
colorectal cancer KRAS_G13D FLT4 87 70 Female -0.22 -1.02 0.48 1256.39 1.00 908 82 65 5 TRUE 0.24
colorectal cancer KRAS_G13D FLT4 87 69 Male -0.23 -1.11 0.48 924.75 1.00 1089 83 65 4 TRUE 0.25
colorectal cancer KRAS_G13D FLT4 174 139 Sex:overall -0.22 -1.12 0.56 1159.36 1.00 1997 165 130 9 TRUE 0.20
colorectal cancer KRAS_G13D PTPRD 87 48 Female -0.12 -1.07 0.66 1214.81 1.00 924 84 45 3 FALSE 0.10
colorectal cancer KRAS_G13D PTPRD 88 55 Male 0.00 -0.87 0.77 1198.19 1.00 1110 83 50 5 FALSE 0.00
colorectal cancer KRAS_G13D PTPRD 175 103 Sex:overall -0.05 -1.01 0.80 1480.89 1.00 2034 167 95 8 FALSE 0.04
colorectal cancer KRAS_G13D RET 95 36 Female 0.70 -0.20 1.59 670.91 1.00 1029 88 29 7 TRUE 0.89
colorectal cancer KRAS_G13D RET 94 29 Male 0.01 -1.69 1.06 940.84 1.01 1243 93 28 1 TRUE 0.00
colorectal cancer KRAS_G13D RET 189 65 Sex:overall 0.38 -1.13 1.60 1312.36 1.00 2272 181 57 8 TRUE 0.22
colorectal cancer KRAS_G13D KDM5A 88 31 Female 0.34 -0.58 1.15 1134.83 1.00 937 84 27 4 FALSE 0.34
colorectal cancer KRAS_G13D KDM5A 87 65 Male 0.31 -0.54 1.00 1111.55 1.01 1103 81 59 6 FALSE 0.35
colorectal cancer KRAS_G13D KDM5A 175 96 Sex:overall 0.32 -0.82 1.39 1356.15 1.00 2040 165 86 10 FALSE 0.26
colorectal cancer KRAS_G13D PIK3C2G 84 30 Female -1.38 -5.62 0.35 1133.00 1.00 907 84 30 0 FALSE 0.42
colorectal cancer KRAS_G13D PIK3C2G 89 57 Male 0.05 -0.99 0.95 1399.53 1.00 1072 83 51 6 FALSE 0.04
colorectal cancer KRAS_G13D PIK3C2G 173 87 Sex:overall -0.61 -3.32 1.06 1387.64 1.00 1979 167 81 6 FALSE 0.23
colorectal cancer KRAS_G13D CREBBP 89 81 Female 0.15 -0.62 0.70 863.04 1.00 905 83 75 6 TRUE 0.19
colorectal cancer KRAS_G13D CREBBP 88 107 Male 0.35 -0.21 0.95 971.15 1.00 1077 76 95 12 TRUE 0.63
colorectal cancer KRAS_G13D CREBBP 177 188 Sex:overall 0.24 -0.56 0.95 1471.04 1.00 1982 159 170 18 TRUE 0.28
colorectal cancer KRAS_G13D AXIN2 88 48 Female 0.19 -0.48 1.02 28.02 1.11 929 82 42 6 TRUE 0.19
colorectal cancer KRAS_G13D AXIN2 87 67 Male 0.11 -0.54 0.84 37.91 1.09 1093 82 62 5 TRUE 0.11
colorectal cancer KRAS_G13D AXIN2 175 115 Sex:overall 0.16 -0.58 1.06 43.70 1.08 2022 164 104 11 TRUE 0.14
colorectal cancer KRAS_G13D DOT1L 87 30 Female 0.25 -0.78 1.10 1021.34 1.00 938 84 27 3 FALSE 0.23
colorectal cancer KRAS_G13D DOT1L 87 54 Male 0.39 -0.47 1.12 1190.83 1.00 1109 81 48 6 FALSE 0.48
colorectal cancer KRAS_G13D DOT1L 174 84 Sex:overall 0.33 -0.81 1.31 1081.43 1.00 2047 165 75 9 FALSE 0.26
colorectal cancer KRAS_G13D PTPRS 85 107 Female 0.20 -0.40 0.73 1056.79 1.00 853 76 98 9 FALSE 0.33
colorectal cancer KRAS_G13D PTPRS 89 147 Male 0.37 -0.12 0.88 866.75 1.00 1012 73 131 16 FALSE 0.80
colorectal cancer KRAS_G13D PTPRS 174 254 Sex:overall 0.29 -0.42 0.91 1005.49 1.00 1865 149 229 25 FALSE 0.35
colorectal cancer KRAS_G13D SMARCA4 87 77 Female -0.02 -0.73 0.58 506.49 1.01 905 82 72 5 FALSE 0.03
colorectal cancer KRAS_G13D SMARCA4 89 92 Male 0.10 -0.53 0.73 326.22 1.01 1085 80 83 9 FALSE 0.12
colorectal cancer KRAS_G13D SMARCA4 176 169 Sex:overall 0.04 -0.70 0.77 565.30 1.01 1990 162 155 14 FALSE 0.03
colorectal cancer KRAS_G13D PTPRT 87 71 Female 0.28 -0.54 0.88 1322.46 1.00 903 81 65 6 FALSE 0.35
colorectal cancer KRAS_G13D PTPRT 91 114 Male 0.65 0.11 1.21 916.11 1.00 1060 75 98 16 FALSE 1.68
colorectal cancer KRAS_G13D PTPRT 178 185 Sex:overall 0.48 -0.47 1.31 1313.91 1.00 1963 156 163 22 FALSE 0.45
colorectal cancer KRAS_G13D HGF 87 14 Female 0.35 -0.92 1.47 1466.22 1.00 952 85 12 2 FALSE 0.24
colorectal cancer KRAS_G13D HGF 87 42 Male 0.29 -0.77 1.19 1098.97 1.00 1112 83 38 4 FALSE 0.24
colorectal cancer KRAS_G13D HGF 174 56 Sex:overall 0.30 -1.33 1.83 1420.57 1.00 2064 168 50 6 FALSE 0.15
colorectal cancer KRAS_G13D BLM 87 26 Female -0.06 -1.73 0.94 362.72 1.01 940 86 25 1 TRUE 0.03
colorectal cancer KRAS_G13D BLM 87 44 Male 0.42 -0.55 1.27 1060.44 1.00 1115 81 38 6 TRUE 0.44
colorectal cancer KRAS_G13D BLM 174 70 Sex:overall 0.16 -1.37 1.30 676.83 1.00 2055 167 63 7 TRUE 0.09
colorectal cancer KRAS_G13D PIK3CA 100 244 Female 0.90 0.51 1.24 691.46 1.02 868 64 208 36 TRUE 6.36
colorectal cancer KRAS_G13D PIK3CA 98 267 Male 0.90 0.54 1.24 574.49 1.02 1066 63 232 35 TRUE 6.66
colorectal cancer KRAS_G13D PIK3CA 198 511 Sex:overall 0.89 0.43 1.30 1026.09 1.01 1934 127 440 71 TRUE 3.98
colorectal cancer KRAS_G13D ESR1 87 26 Female 0.53 -0.39 1.38 920.81 1.00 943 83 22 4 TRUE 0.65
colorectal cancer KRAS_G13D ESR1 88 46 Male 0.50 -0.34 1.23 1124.23 1.00 1106 83 41 5 TRUE 0.70
colorectal cancer KRAS_G13D ESR1 175 72 Sex:overall 0.51 -0.46 1.42 1309.21 1.00 2049 166 63 9 TRUE 0.57
colorectal cancer KRAS_G13D ALK 96 55 Female 0.98 0.38 1.55 1266.67 1.00 1017 85 44 11 TRUE 3.06
colorectal cancer KRAS_G13D ALK 95 60 Male 0.88 0.26 1.46 1221.78 1.00 1227 87 52 8 TRUE 2.42
colorectal cancer KRAS_G13D ALK 191 115 Sex:overall 0.93 0.24 1.60 1271.35 1.00 2244 172 96 19 TRUE 1.87
colorectal cancer KRAS_G13D RNF43 88 140 Female -0.50 -1.43 0.25 1200.80 1.00 865 82 134 6 TRUE 0.60
colorectal cancer KRAS_G13D RNF43 92 127 Male 0.60 -0.03 1.18 1440.91 1.00 1063 75 110 17 TRUE 1.23
colorectal cancer KRAS_G13D RNF43 180 267 Sex:overall 0.03 -1.44 1.36 1334.32 1.00 1928 157 244 23 TRUE 0.01
colorectal cancer KRAS_G13D LATS1 84 19 Female -0.12 -1.36 0.95 1142.27 1.00 916 82 17 2 FALSE 0.07
colorectal cancer KRAS_G13D LATS1 87 36 Male -0.23 -1.56 0.80 1082.20 1.00 1087 85 34 2 FALSE 0.16
colorectal cancer KRAS_G13D LATS1 171 55 Sex:overall -0.15 -1.50 1.02 1185.52 1.00 2003 167 51 4 FALSE 0.09
colorectal cancer KRAS_G13D LATS2 84 26 Female -0.32 -1.87 0.66 1087.71 1.00 910 83 25 1 FALSE 0.21
colorectal cancer KRAS_G13D LATS2 87 44 Male -0.10 -1.15 0.81 788.49 1.01 1076 83 40 4 FALSE 0.07
colorectal cancer KRAS_G13D LATS2 171 70 Sex:overall -0.19 -1.47 0.92 1178.58 1.01 1986 166 65 5 FALSE 0.12
colorectal cancer KRAS_G13D PTEN 96 80 Female 0.62 0.06 1.09 1192.89 1.00 1006 86 70 10 TRUE 1.78
colorectal cancer KRAS_G13D PTEN 97 105 Male 0.68 0.16 1.17 992.28 1.00 1201 83 91 14 TRUE 2.13
colorectal cancer KRAS_G13D PTEN 193 185 Sex:overall 0.65 0.05 1.24 1554.66 1.00 2207 169 161 24 TRUE 1.43
colorectal cancer KRAS_G13D BCOR 89 59 Female 0.20 -0.57 0.89 1146.25 1.00 922 82 52 7 FALSE 0.23
colorectal cancer KRAS_G13D BCOR 87 53 Male 0.03 -0.88 0.77 1078.11 1.00 1101 84 50 3 FALSE 0.03
colorectal cancer KRAS_G13D BCOR 176 112 Sex:overall 0.12 -0.84 1.00 1146.75 1.00 2023 166 102 10 FALSE 0.10
colorectal cancer KRAS_G13D CTNNB1 94 74 Female 0.42 -0.20 0.97 64.03 1.05 994 86 66 8 TRUE 0.77
colorectal cancer KRAS_G13D CTNNB1 94 89 Male 0.49 -0.05 1.07 46.12 1.06 1197 83 78 11 TRUE 0.95
colorectal cancer KRAS_G13D CTNNB1 188 163 Sex:overall 0.46 -0.18 1.11 72.94 1.04 2191 169 144 19 TRUE 0.71
colorectal cancer KRAS_G13D ARID1A 89 149 Female 0.01 -0.72 0.61 220.37 1.01 873 80 140 9 TRUE 0.01
colorectal cancer KRAS_G13D ARID1A 93 166 Male 0.34 -0.18 0.85 978.41 1.00 1037 74 147 19 TRUE 0.71
colorectal cancer KRAS_G13D ARID1A 182 315 Sex:overall 0.17 -0.63 0.87 1360.24 1.00 1910 154 287 28 TRUE 0.19
colorectal cancer KRAS_G13D PIK3R1 87 44 Female 0.19 -0.55 0.95 101.22 1.02 928 82 39 5 TRUE 0.20
colorectal cancer KRAS_G13D PIK3R1 88 72 Male 0.16 -0.53 0.89 113.18 1.03 1094 82 66 6 TRUE 0.17
colorectal cancer KRAS_G13D PIK3R1 175 116 Sex:overall 0.18 -0.65 1.09 197.81 1.02 2022 164 105 11 TRUE 0.16
colorectal cancer KRAS_G13D IKZF1 87 42 Female 0.44 -0.40 1.17 805.57 1.00 930 82 37 5 TRUE 0.59
colorectal cancer KRAS_G13D IKZF1 87 44 Male 0.44 -0.32 1.18 871.73 1.00 1109 82 39 5 TRUE 0.61
colorectal cancer KRAS_G13D IKZF1 174 86 Sex:overall 0.44 -0.46 1.21 1092.81 1.00 2039 164 76 10 TRUE 0.50
colorectal cancer KRAS_G13D TERT 87 40 Female 0.06 -0.81 0.77 544.42 1.00 929 84 37 3 TRUE 0.05
colorectal cancer KRAS_G13D TERT 87 58 Male 0.20 -0.56 0.91 264.21 1.01 1103 81 52 6 TRUE 0.20
colorectal cancer KRAS_G13D TERT 174 98 Sex:overall 0.12 -0.82 0.97 384.10 1.01 2032 165 89 9 TRUE 0.10
colorectal cancer KRAS_G13D FAT1 91 97 Female 0.32 -0.55 0.90 843.87 1.00 896 83 89 8 FALSE 0.40
colorectal cancer KRAS_G13D FAT1 96 130 Male 0.86 0.33 1.43 1152.17 1.00 1080 74 108 22 FALSE 2.64
colorectal cancer KRAS_G13D FAT1 187 227 Sex:overall 0.57 -0.51 1.42 1400.57 1.00 1976 157 197 30 FALSE 0.61
colorectal cancer KRAS_G13D FGFR4 87 19 Female 0.71 -0.30 1.61 1451.56 1.00 950 84 16 3 TRUE 0.86
colorectal cancer KRAS_G13D FGFR4 87 34 Male 0.77 -0.07 1.61 1452.40 1.00 1120 82 29 5 TRUE 1.14
colorectal cancer KRAS_G13D FGFR4 174 53 Sex:overall 0.74 -0.38 1.78 1468.47 1.00 2070 166 45 8 TRUE 0.71
colorectal cancer KRAS_G13D CIC 87 58 Female -0.40 -1.29 0.35 1424.01 1.00 921 84 55 3 TRUE 0.47
colorectal cancer KRAS_G13D CIC 88 79 Male -0.32 -1.14 0.38 1410.89 1.00 1088 83 74 5 TRUE 0.40
colorectal cancer KRAS_G13D CIC 175 137 Sex:overall -0.36 -1.32 0.48 1462.91 1.00 2009 167 129 8 TRUE 0.37
colorectal cancer KRAS_G13D KDM6A 87 31 Female -1.27 -4.59 0.22 905.66 1.00 935 87 31 0 FALSE 0.41
colorectal cancer KRAS_G13D KDM6A 87 31 Male -0.38 -1.85 0.88 1335.31 1.00 1120 84 28 3 FALSE 0.23
colorectal cancer KRAS_G13D KDM6A 174 62 Sex:overall -0.79 -2.92 0.76 1187.80 1.00 2055 171 59 3 FALSE 0.36
colorectal cancer KRAS_G13D NCOR1 88 54 Female 0.31 -0.44 0.97 1250.62 1.00 920 82 48 6 FALSE 0.43
colorectal cancer KRAS_G13D NCOR1 88 81 Male 0.34 -0.33 0.95 1391.46 1.00 1093 80 73 8 FALSE 0.54
colorectal cancer KRAS_G13D NCOR1 176 135 Sex:overall 0.32 -0.45 1.08 1570.72 1.00 2013 162 121 14 FALSE 0.33
colorectal cancer KRAS_G13D POLE 89 59 Female 0.38 -0.32 0.98 1247.25 1.00 918 83 53 6 TRUE 0.62
colorectal cancer KRAS_G13D POLE 89 82 Male 0.49 -0.16 1.10 1374.14 1.00 1091 79 72 10 TRUE 0.94
colorectal cancer KRAS_G13D POLE 178 141 Sex:overall 0.43 -0.45 1.11 1101.91 1.00 2009 162 125 16 TRUE 0.54
colorectal cancer KRAS_G13D ABL1 95 34 Female 0.16 -0.74 0.98 1265.88 1.00 1028 92 31 3 TRUE 0.14
colorectal cancer KRAS_G13D ABL1 95 39 Male 0.22 -0.68 1.03 1427.35 1.00 1240 91 35 4 TRUE 0.21
colorectal cancer KRAS_G13D ABL1 190 73 Sex:overall 0.20 -0.81 1.15 1355.34 1.00 2268 183 66 7 TRUE 0.15
colorectal cancer KRAS_G13D FOXP1 88 24 Female 0.46 -0.48 1.32 1313.34 1.00 943 84 20 4 FALSE 0.49
colorectal cancer KRAS_G13D FOXP1 87 46 Male 0.32 -0.63 1.11 1214.24 1.00 1109 83 42 4 FALSE 0.34
colorectal cancer KRAS_G13D FOXP1 175 70 Sex:overall 0.39 -0.67 1.39 1346.74 1.00 2052 167 62 8 FALSE 0.33
colorectal cancer KRAS_G13D NOTCH2 84 30 Female 0.21 -0.89 1.04 1006.01 1.00 910 82 28 2 TRUE 0.18
colorectal cancer KRAS_G13D NOTCH2 87 43 Male 0.46 -0.36 1.24 1030.11 1.00 1082 81 37 6 TRUE 0.54
colorectal cancer KRAS_G13D NOTCH2 171 73 Sex:overall 0.34 -0.74 1.28 1103.04 1.00 1992 163 65 8 TRUE 0.27
colorectal cancer KRAS_G13D TGFBR2 87 53 Female 0.44 -0.37 1.07 1120.87 1.00 918 82 48 5 TRUE 0.65
colorectal cancer KRAS_G13D TGFBR2 87 61 Male 0.62 -0.05 1.30 991.38 1.00 1098 78 52 9 TRUE 1.15
colorectal cancer KRAS_G13D TGFBR2 174 114 Sex:overall 0.52 -0.33 1.29 1249.40 1.00 2016 160 100 14 TRUE 0.64
colorectal cancer KRAS_G13D SMO 94 32 Female -0.32 -1.68 0.65 1342.90 1.00 1028 93 31 1 TRUE 0.23
colorectal cancer KRAS_G13D SMO 95 39 Male -0.06 -1.17 0.87 1003.08 1.00 1239 91 35 4 TRUE 0.04
colorectal cancer KRAS_G13D SMO 189 71 Sex:overall -0.18 -1.39 0.87 983.50 1.00 2267 184 66 5 TRUE 0.11
colorectal cancer KRAS_G13D RPS6KA4 84 26 Female 0.60 -0.50 1.39 1356.32 1.00 913 81 23 3 FALSE 0.69
colorectal cancer KRAS_G13D RPS6KA4 88 37 Male 0.72 -0.07 1.43 667.70 1.00 1083 82 31 6 FALSE 1.17
colorectal cancer KRAS_G13D RPS6KA4 172 63 Sex:overall 0.65 -0.31 1.48 1204.14 1.00 1996 163 54 9 FALSE 0.82
colorectal cancer KRAS_G13D KMT2A 88 69 Female 0.07 -0.93 0.76 948.19 1.00 915 84 65 4 FALSE 0.06
colorectal cancer KRAS_G13D KMT2A 91 79 Male 0.44 -0.25 1.11 1236.59 1.00 1091 80 68 11 FALSE 0.69
colorectal cancer KRAS_G13D KMT2A 179 148 Sex:overall 0.26 -0.64 1.12 1166.86 1.00 2006 164 133 15 FALSE 0.25
colorectal cancer KRAS_G13D JAK3 94 33 Female -1.34 -4.86 0.32 1248.57 1.00 1028 94 33 0 TRUE 0.42
colorectal cancer KRAS_G13D JAK3 94 30 Male -0.32 -1.86 1.00 1293.87 1.00 1244 91 27 3 TRUE 0.18
colorectal cancer KRAS_G13D JAK3 188 63 Sex:overall -0.82 -3.27 0.77 1406.66 1.00 2272 185 60 3 TRUE 0.38
colorectal cancer KRAS_G13D BRCA2 89 75 Female 0.05 -0.84 0.73 1502.65 1.00 905 84 70 5 TRUE 0.05
colorectal cancer KRAS_G13D BRCA2 94 115 Male 0.50 -0.10 1.13 1192.13 1.00 1089 79 100 15 TRUE 1.00
colorectal cancer KRAS_G13D BRCA2 183 190 Sex:overall 0.28 -0.72 1.12 1584.80 1.00 1994 163 170 20 TRUE 0.25
colorectal cancer KRAS_G13D NOTCH3 88 88 Female 0.12 -0.72 0.73 916.83 1.00 896 82 82 6 TRUE 0.13
colorectal cancer KRAS_G13D NOTCH3 87 112 Male 0.46 -0.13 1.04 1444.86 1.00 1075 73 98 14 TRUE 0.91
colorectal cancer KRAS_G13D NOTCH3 175 200 Sex:overall 0.27 -0.63 1.00 1533.24 1.00 1971 155 180 20 TRUE 0.30
colorectal cancer KRAS_G13D NOTCH4 85 45 Female 0.08 -0.72 0.79 1348.80 1.00 894 81 41 4 TRUE 0.07
colorectal cancer KRAS_G13D NOTCH4 89 77 Male 0.14 -0.60 0.81 1393.56 1.00 1055 82 70 7 TRUE 0.16
colorectal cancer KRAS_G13D NOTCH4 174 122 Sex:overall 0.11 -0.78 0.89 1481.55 1.00 1949 163 111 11 TRUE 0.10
colorectal cancer KRAS_G13D FGFR3 94 25 Female -0.74 -2.27 0.57 216.67 1.01 1034 93 24 1 TRUE 0.48
colorectal cancer KRAS_G13D FGFR3 94 35 Male -0.64 -2.06 0.59 198.36 1.01 1241 92 33 2 TRUE 0.45
colorectal cancer KRAS_G13D FGFR3 188 60 Sex:overall -0.69 -2.15 0.60 194.65 1.01 2275 185 57 3 TRUE 0.46
colorectal cancer KRAS_G13D IGF1R 87 31 Female -0.47 -2.00 0.61 929.88 1.00 936 86 30 1 TRUE 0.32
colorectal cancer KRAS_G13D IGF1R 87 49 Male -0.22 -1.34 0.77 695.21 1.01 1109 83 45 4 TRUE 0.17
colorectal cancer KRAS_G13D IGF1R 174 80 Sex:overall -0.35 -1.78 0.83 922.65 1.01 2045 169 75 5 TRUE 0.22
colorectal cancer KRAS_G13D KDM5C 87 41 Female -0.65 -2.71 0.64 735.64 1.00 934 86 40 1 FALSE 0.36
colorectal cancer KRAS_G13D KDM5C 88 28 Male 0.57 -0.57 1.63 918.14 1.00 1124 83 23 5 FALSE 0.47
colorectal cancer KRAS_G13D KDM5C 175 69 Sex:overall -0.02 -2.04 1.79 996.49 1.00 2058 169 63 6 FALSE 0.01
colorectal cancer KRAS_G13D EPHB1 87 32 Female -1.03 -2.54 0.22 1280.78 1.00 933 86 31 1 FALSE 0.87
colorectal cancer KRAS_G13D EPHB1 87 50 Male -0.95 -2.28 0.17 1142.71 1.00 1101 85 48 2 FALSE 0.90
colorectal cancer KRAS_G13D EPHB1 174 82 Sex:overall -0.98 -2.50 0.26 1186.54 1.00 2034 171 79 3 FALSE 0.79
colorectal cancer KRAS_G13D IRS2 87 29 Female -0.31 -1.99 0.71 1288.39 1.00 939 86 28 1 FALSE 0.18
colorectal cancer KRAS_G13D IRS2 87 58 Male 0.35 -0.56 1.14 1305.99 1.00 1101 80 51 7 FALSE 0.38
colorectal cancer KRAS_G13D IRS2 174 87 Sex:overall 0.04 -1.58 1.45 1238.11 1.00 2040 166 79 8 FALSE 0.02
colorectal cancer KRAS_G13D FANCA 87 31 Female 0.87 0.03 1.60 1536.68 1.00 939 82 26 5 TRUE 1.60
colorectal cancer KRAS_G13D FANCA 87 34 Male 0.92 0.11 1.65 1446.66 1.00 1123 81 28 6 TRUE 1.74
colorectal cancer KRAS_G13D FANCA 174 65 Sex:overall 0.88 0.01 1.67 1280.66 1.00 2062 163 54 11 TRUE 1.39
colorectal cancer KRAS_G13D PIK3CB 84 24 Female -1.10 -5.21 0.63 773.76 1.00 913 84 24 0 FALSE 0.33
colorectal cancer KRAS_G13D PIK3CB 89 44 Male 0.06 -1.16 1.03 617.04 1.00 1085 84 39 5 FALSE 0.04
colorectal cancer KRAS_G13D PIK3CB 173 68 Sex:overall -0.46 -3.05 1.06 1022.75 1.00 1998 168 63 5 FALSE 0.18
colorectal cancer KRAS_G13D ERBB3 87 52 Female 0.37 -0.55 1.02 217.80 1.01 923 83 48 4 TRUE 0.43
colorectal cancer KRAS_G13D ERBB3 89 70 Male 0.66 -0.03 1.27 361.76 1.01 1092 78 59 11 TRUE 1.34
colorectal cancer KRAS_G13D ERBB3 176 122 Sex:overall 0.53 -0.33 1.33 710.72 1.00 2015 161 107 15 TRUE 0.54
colorectal cancer KRAS_G13D SMAD4 95 170 Female -0.24 -0.77 0.25 1345.82 1.00 914 83 158 12 TRUE 0.44
colorectal cancer KRAS_G13D SMAD4 95 190 Male -0.28 -0.84 0.21 1367.41 1.00 1106 85 180 10 TRUE 0.54
colorectal cancer KRAS_G13D SMAD4 190 360 Sex:overall -0.26 -0.92 0.31 1392.82 1.00 2020 168 338 22 TRUE 0.36
colorectal cancer KRAS_G13D ATM 94 100 Female 0.16 -0.57 0.76 1356.47 1.00 982 87 93 7 TRUE 0.20
colorectal cancer KRAS_G13D ATM 101 131 Male 0.46 -0.01 1.07 66.34 1.04 1186 84 114 17 TRUE 0.95
colorectal cancer KRAS_G13D ATM 195 231 Sex:overall 0.31 -0.41 1.05 1175.35 1.01 2168 171 207 24 TRUE 0.39
colorectal cancer KRAS_G13D RB1 95 23 Female 0.06 -1.18 1.12 1496.12 1.00 1040 92 20 3 TRUE 0.04
colorectal cancer KRAS_G13D RB1 95 45 Male -0.24 -1.52 0.72 1318.69 1.00 1236 93 43 2 TRUE 0.18
colorectal cancer KRAS_G13D RB1 190 68 Sex:overall -0.11 -1.50 1.07 1393.56 1.00 2276 185 63 5 TRUE 0.06
colorectal cancer KRAS_G13D KMT2D 91 187 Female -0.11 -0.78 0.40 934.82 1.00 861 80 176 11 FALSE 0.15
colorectal cancer KRAS_G13D KMT2D 94 201 Male 0.32 -0.18 0.86 972.70 1.00 1035 72 179 22 FALSE 0.64
colorectal cancer KRAS_G13D KMT2D 185 388 Sex:overall 0.11 -0.72 0.93 1188.76 1.00 1896 152 355 33 FALSE 0.08
colorectal cancer KRAS_G13D TSC2 88 62 Female 0.04 -0.84 0.76 1206.11 1.00 919 82 56 6 TRUE 0.03
colorectal cancer KRAS_G13D TSC2 87 53 Male -0.08 -1.03 0.67 1178.44 1.00 1104 84 50 3 TRUE 0.07
colorectal cancer KRAS_G13D TSC2 175 115 Sex:overall -0.01 -1.06 0.89 1406.98 1.00 2023 166 106 9 TRUE 0.01
colorectal cancer KRAS_G13D APC 134 1110 Female 0.47 0.10 0.82 1320.49 1.00 396 28 1004 106 TRUE 2.01
colorectal cancer KRAS_G13D APC 149 1428 Male 0.48 0.11 0.82 1285.33 1.00 442 25 1304 124 TRUE 2.13
colorectal cancer KRAS_G13D APC 283 2538 Sex:overall 0.48 0.01 0.93 1297.12 1.00 838 53 2308 230 TRUE 1.25
colorectal cancer KRAS_G13D ERBB2 95 38 Female 0.79 0.05 1.50 1468.21 1.00 1028 88 31 7 TRUE 1.49
colorectal cancer KRAS_G13D ERBB2 94 66 Male 0.72 -0.01 1.36 1407.36 1.00 1218 86 58 8 TRUE 1.41
colorectal cancer KRAS_G13D ERBB2 189 104 Sex:overall 0.76 -0.18 1.72 1421.90 1.00 2246 174 89 15 TRUE 0.99
colorectal cancer KRAS_G13D JAK1 87 29 Female 0.37 -1.14 1.38 1004.58 1.00 941 85 27 2 TRUE 0.24
colorectal cancer KRAS_G13D JAK1 92 46 Male 1.31 0.59 2.01 1350.31 1.00 1117 80 34 12 TRUE 3.52
colorectal cancer KRAS_G13D JAK1 179 75 Sex:overall 0.82 -0.92 2.09 1404.90 1.00 2058 165 61 14 TRUE 0.57
colorectal cancer KRAS_G13D ARID2 87 54 Female 0.05 -0.81 0.74 996.69 1.00 919 82 49 5 FALSE 0.04
colorectal cancer KRAS_G13D ARID2 88 56 Male 0.01 -0.83 0.73 1024.72 1.00 1103 84 52 4 FALSE 0.01
colorectal cancer KRAS_G13D ARID2 175 110 Sex:overall 0.03 -0.88 0.82 1016.12 1.00 2022 166 101 9 FALSE 0.02
colorectal cancer KRAS_G13D SOX17 84 52 Female -0.28 -1.65 0.66 1077.16 1.00 886 82 50 2 FALSE 0.20
colorectal cancer KRAS_G13D SOX17 87 46 Male 0.22 -0.72 1.12 1343.86 1.00 1079 81 40 6 FALSE 0.20
colorectal cancer KRAS_G13D SOX17 171 98 Sex:overall 0.00 -1.32 1.21 1445.39 1.00 1965 163 90 8 FALSE 0.00
colorectal cancer KRAS_G13D MTOR 90 75 Female 0.42 -0.25 1.05 1376.36 1.00 906 82 67 8 TRUE 0.71
colorectal cancer KRAS_G13D MTOR 88 65 Male 0.58 -0.06 1.24 1404.00 1.00 1098 79 56 9 TRUE 1.13
colorectal cancer KRAS_G13D MTOR 178 140 Sex:overall 0.49 -0.45 1.31 1417.73 1.00 2004 161 123 17 TRUE 0.56
colorectal cancer KRAS_G13D IRS1 84 43 Female 0.00 -1.61 0.98 1033.78 1.00 896 82 41 2 FALSE 0.00
colorectal cancer KRAS_G13D IRS1 90 54 Male 0.91 0.20 1.65 1051.79 1.00 1076 79 43 11 FALSE 1.83
colorectal cancer KRAS_G13D IRS1 174 97 Sex:overall 0.44 -1.11 1.79 1241.80 1.00 1972 161 84 13 FALSE 0.26
colorectal cancer KRAS_G13D NOTCH1 96 85 Female 0.17 -0.60 0.74 1254.04 1.00 999 90 79 6 TRUE 0.20
colorectal cancer KRAS_G13D NOTCH1 99 87 Male 0.50 -0.09 1.12 1418.48 1.00 1209 87 75 12 TRUE 0.98
colorectal cancer KRAS_G13D NOTCH1 195 172 Sex:overall 0.33 -0.52 1.10 1398.37 1.00 2208 177 154 18 TRUE 0.37
colorectal cancer KRAS_G13D NTRK1 87 24 Female 0.13 -1.55 1.12 122.97 1.03 942 86 23 1 TRUE 0.07
colorectal cancer KRAS_G13D NTRK1 88 40 Male 0.72 -0.18 1.59 808.88 1.01 1114 81 33 7 TRUE 1.00
colorectal cancer KRAS_G13D NTRK1 175 64 Sex:overall 0.43 -1.03 1.63 1208.45 1.01 2056 167 56 8 TRUE 0.26
colorectal cancer KRAS_G13D CASP8 84 38 Female -0.05 -1.53 1.17 1258.65 1.00 901 82 36 2 FALSE 0.03
colorectal cancer KRAS_G13D CASP8 93 58 Male 1.59 0.96 2.21 1410.31 1.00 1078 76 41 17 FALSE 6.09
colorectal cancer KRAS_G13D CASP8 177 96 Sex:overall 0.75 -1.26 2.48 1540.56 1.00 1979 158 77 19 FALSE 0.37
colorectal cancer KRAS_G13D SETD2 87 34 Female 0.02 -1.39 1.08 1265.71 1.00 936 85 32 2 FALSE 0.01
colorectal cancer KRAS_G13D SETD2 92 79 Male 0.95 0.35 1.59 1515.40 1.00 1093 78 65 14 FALSE 2.57
colorectal cancer KRAS_G13D SETD2 179 113 Sex:overall 0.50 -1.11 1.82 1405.38 1.00 2029 163 97 16 FALSE 0.31
colorectal cancer KRAS_G13D PBRM1 87 38 Female 0.03 -1.04 0.83 1263.66 1.00 931 85 36 2 TRUE 0.03
colorectal cancer KRAS_G13D PBRM1 90 56 Male 0.28 -0.47 1.04 1233.67 1.00 1104 83 49 7 TRUE 0.34
colorectal cancer KRAS_G13D PBRM1 177 94 Sex:overall 0.15 -1.01 1.08 1709.91 1.00 2035 168 85 9 TRUE 0.11
colorectal cancer KRAS_G13D EPHA3 87 52 Female 0.45 -0.36 1.09 1088.28 1.00 921 82 47 5 FALSE 0.65
colorectal cancer KRAS_G13D EPHA3 89 61 Male 0.60 -0.08 1.27 1188.03 1.00 1099 80 52 9 FALSE 1.09
colorectal cancer KRAS_G13D EPHA3 176 113 Sex:overall 0.53 -0.28 1.28 1293.45 1.00 2020 162 99 14 FALSE 0.67
colorectal cancer KRAS_G13D KIT 94 23 Female -2.06 -4.78 -0.11 785.28 1.00 1036 94 23 0 TRUE 0.98
colorectal cancer KRAS_G13D KIT 94 31 Male -1.86 -4.53 0.08 731.45 1.00 1243 93 30 1 TRUE 0.93
colorectal cancer KRAS_G13D KIT 188 54 Sex:overall -1.94 -4.76 0.07 778.92 1.00 2279 187 53 1 TRUE 0.95
colorectal cancer KRAS_G13D KDR 95 26 Female 0.57 -0.41 1.36 1312.79 1.00 1037 92 23 3 TRUE 0.70
colorectal cancer KRAS_G13D KDR 98 49 Male 0.80 0.03 1.49 1315.01 1.00 1233 90 41 8 TRUE 1.51
colorectal cancer KRAS_G13D KDR 193 75 Sex:overall 0.70 -0.35 1.65 1532.23 1.00 2270 182 64 11 TRUE 0.72
colorectal cancer KRAS_G13D RICTOR 87 26 Female 0.45 -0.79 1.30 1329.47 1.00 942 85 24 2 FALSE 0.39
colorectal cancer KRAS_G13D RICTOR 89 44 Male 0.96 0.20 1.73 372.29 1.01 1118 80 35 9 FALSE 1.81
colorectal cancer KRAS_G13D RICTOR 176 70 Sex:overall 0.69 -0.69 1.68 1151.88 1.00 2060 165 59 11 FALSE 0.59
colorectal cancer KRAS_G13D RAD50 88 21 Female 0.66 -0.32 1.47 1323.15 1.00 947 85 18 3 FALSE 0.84
colorectal cancer KRAS_G13D RAD50 89 39 Male 0.78 -0.06 1.52 1125.50 1.00 1116 83 33 6 FALSE 1.24
colorectal cancer KRAS_G13D RAD50 177 60 Sex:overall 0.71 -0.31 1.68 1464.32 1.00 2063 168 51 9 FALSE 0.75
colorectal cancer KRAS_G13D CSF1R 94 21 Female 0.20 -0.93 1.25 1324.09 1.00 1041 91 18 3 TRUE 0.14
colorectal cancer KRAS_G13D CSF1R 94 35 Male 0.03 -1.13 1.00 1222.53 1.00 1243 92 33 2 TRUE 0.02
colorectal cancer KRAS_G13D CSF1R 188 56 Sex:overall 0.12 -1.10 1.25 1114.92 1.00 2284 183 51 5 TRUE 0.07
colorectal cancer KRAS_G13D PTCH1 91 67 Female 0.40 -0.21 1.00 1112.43 1.00 913 82 58 9 TRUE 0.69
colorectal cancer KRAS_G13D PTCH1 90 78 Male 0.34 -0.28 0.92 1264.57 1.00 1094 83 71 7 TRUE 0.57
colorectal cancer KRAS_G13D PTCH1 181 145 Sex:overall 0.37 -0.32 1.05 1170.47 1.00 2007 165 129 16 TRUE 0.50
colorectal cancer KRAS_G13D TET1 84 40 Female 0.42 -0.36 1.13 1282.07 1.00 901 80 36 4 FALSE 0.56
colorectal cancer KRAS_G13D TET1 93 63 Male 0.57 -0.12 1.20 1201.55 1.00 1076 84 54 9 FALSE 1.00
colorectal cancer KRAS_G13D TET1 177 103 Sex:overall 0.48 -0.37 1.22 1351.85 1.00 1977 164 90 13 FALSE 0.60
colorectal cancer KRAS_G13D FGFR2 94 21 Female 0.14 -1.45 1.16 915.89 1.01 1040 93 20 1 TRUE 0.08
colorectal cancer KRAS_G13D FGFR2 96 32 Male 0.51 -0.57 1.42 979.47 1.00 1243 91 27 5 TRUE 0.50
colorectal cancer KRAS_G13D FGFR2 190 53 Sex:overall 0.32 -1.00 1.40 1081.44 1.00 2283 184 47 6 TRUE 0.20
colorectal cancer KRAS_G13D TBX3 88 37 Female 0.00 -0.98 0.94 186.01 1.01 936 83 32 5 FALSE 0.00
colorectal cancer KRAS_G13D TBX3 87 43 Male -0.36 -1.82 0.61 449.12 1.01 1112 86 42 1 FALSE 0.25
colorectal cancer KRAS_G13D TBX3 175 80 Sex:overall -0.17 -1.34 0.93 551.96 1.01 2048 169 74 6 FALSE 0.11
colorectal cancer KRAS_G13D HNF1A 94 27 Female -0.28 -1.89 0.83 1155.30 1.00 1032 93 26 1 TRUE 0.17
colorectal cancer KRAS_G13D HNF1A 94 25 Male 0.00 -1.24 1.15 767.66 1.01 1249 91 22 3 TRUE 0.00
colorectal cancer KRAS_G13D HNF1A 188 52 Sex:overall -0.14 -1.53 1.03 1412.92 1.00 2281 184 48 4 TRUE 0.07
colorectal cancer KRAS_G13D DICER1 87 29 Female 0.33 -0.92 1.21 1144.68 1.00 938 85 27 2 TRUE 0.28
colorectal cancer KRAS_G13D DICER1 91 47 Male 0.70 -0.04 1.43 1035.79 1.00 1116 83 39 8 TRUE 1.20
colorectal cancer KRAS_G13D DICER1 178 76 Sex:overall 0.51 -0.57 1.50 1424.73 1.00 2054 168 66 10 TRUE 0.47
colorectal cancer KRAS_G13D SMAD3 87 46 Female -0.37 -1.46 0.48 852.29 1.00 926 85 44 2 TRUE 0.35
colorectal cancer KRAS_G13D SMAD3 87 61 Male -0.20 -1.14 0.66 512.72 1.00 1098 82 56 5 TRUE 0.18
colorectal cancer KRAS_G13D SMAD3 174 107 Sex:overall -0.29 -1.35 0.60 882.50 1.00 2024 167 100 7 TRUE 0.25
colorectal cancer KRAS_G13D NTRK3 87 24 Female -1.16 -4.65 0.41 1143.57 1.00 942 87 24 0 FALSE 0.42
colorectal cancer KRAS_G13D NTRK3 87 46 Male -0.21 -1.53 0.85 1397.50 1.00 1110 83 42 4 FALSE 0.14
colorectal cancer KRAS_G13D NTRK3 174 70 Sex:overall -0.70 -2.89 0.75 1399.23 1.00 2052 170 66 4 FALSE 0.32
colorectal cancer KRAS_G13D AXIN1 87 33 Female 0.11 -0.87 0.95 1163.90 1.00 936 85 31 2 FALSE 0.08
colorectal cancer KRAS_G13D AXIN1 88 38 Male 0.32 -0.63 1.18 1387.61 1.00 1118 83 33 5 FALSE 0.32
colorectal cancer KRAS_G13D AXIN1 175 71 Sex:overall 0.22 -0.81 1.13 1386.24 1.00 2054 168 64 7 FALSE 0.16
colorectal cancer KRAS_G13D GRIN2A 87 62 Female -0.32 -1.76 0.45 183.98 1.02 907 85 60 2 FALSE 0.25
colorectal cancer KRAS_G13D GRIN2A 88 74 Male 0.11 -0.66 0.88 765.60 1.00 1090 80 66 8 FALSE 0.11
colorectal cancer KRAS_G13D GRIN2A 175 136 Sex:overall -0.10 -1.27 0.81 621.54 1.01 1997 165 126 10 FALSE 0.07
colorectal cancer KRAS_G13D PALB2 87 20 Female 0.61 -0.64 1.53 1372.13 1.00 947 85 18 2 TRUE 0.58
colorectal cancer KRAS_G13D PALB2 89 36 Male 0.94 0.13 1.75 1108.87 1.00 1118 82 29 7 TRUE 1.63
colorectal cancer KRAS_G13D PALB2 176 56 Sex:overall 0.77 -0.46 1.78 1307.47 1.00 2065 167 47 9 TRUE 0.76
colorectal cancer KRAS_G13D CTCF 88 40 Female 0.04 -1.44 1.05 626.62 1.00 931 86 38 2 FALSE 0.02
colorectal cancer KRAS_G13D CTCF 89 50 Male 0.90 0.10 1.66 551.46 1.00 1111 79 40 10 FALSE 1.58
colorectal cancer KRAS_G13D CTCF 177 90 Sex:overall 0.46 -1.15 1.59 1472.61 1.00 2042 165 78 12 FALSE 0.31
colorectal cancer KRAS_G13D CDH1 94 21 Female -0.78 -4.01 0.67 914.68 1.00 1043 94 21 0 TRUE 0.28
colorectal cancer KRAS_G13D CDH1 94 33 Male 0.08 -1.08 1.22 635.33 1.00 1243 90 29 4 TRUE 0.05
colorectal cancer KRAS_G13D CDH1 188 54 Sex:overall -0.34 -2.44 1.09 1292.71 1.00 2286 184 50 4 TRUE 0.15
colorectal cancer KRAS_G13D CDK12 88 42 Female -0.08 -1.12 0.87 793.85 1.00 932 83 37 5 FALSE 0.06
colorectal cancer KRAS_G13D CDK12 87 48 Male -0.50 -2.15 0.48 1056.89 1.00 1107 86 47 1 FALSE 0.34
colorectal cancer KRAS_G13D CDK12 175 90 Sex:overall -0.29 -1.74 0.84 1270.77 1.00 2039 169 84 6 FALSE 0.18
colorectal cancer KRAS_G13D DNMT1 84 39 Female 0.22 -0.67 0.94 948.35 1.00 900 80 35 4 FALSE 0.23
colorectal cancer KRAS_G13D DNMT1 87 51 Male 0.24 -0.59 0.94 1234.58 1.00 1077 82 46 5 FALSE 0.26
colorectal cancer KRAS_G13D DNMT1 171 90 Sex:overall 0.22 -0.68 0.99 1336.17 1.00 1977 162 81 9 FALSE 0.21
colorectal cancer KRAS_G13D BRD4 87 31 Female -0.61 -2.23 0.51 1330.89 1.00 934 86 30 1 FALSE 0.43
colorectal cancer KRAS_G13D BRD4 87 57 Male -0.30 -1.41 0.68 1414.98 1.00 1100 83 53 4 FALSE 0.24
colorectal cancer KRAS_G13D BRD4 174 88 Sex:overall -0.45 -1.82 0.82 1287.24 1.00 2034 169 83 5 FALSE 0.30
colorectal cancer KRAS_G13D ASXL1 87 49 Female 0.24 -0.52 0.95 274.72 1.01 926 82 44 5 TRUE 0.29
colorectal cancer KRAS_G13D ASXL1 87 60 Male 0.27 -0.48 0.97 256.21 1.01 1096 81 54 6 TRUE 0.34
colorectal cancer KRAS_G13D ASXL1 174 109 Sex:overall 0.26 -0.58 1.02 350.53 1.01 2022 163 98 11 TRUE 0.27
colorectal cancer KRAS_G13D EP300 88 53 Female -0.10 -0.96 0.61 1372.17 1.00 925 85 50 3 TRUE 0.09
colorectal cancer KRAS_G13D EP300 89 72 Male 0.06 -0.71 0.76 1266.81 1.00 1091 82 65 7 TRUE 0.06
colorectal cancer KRAS_G13D EP300 177 125 Sex:overall -0.02 -0.96 0.76 1546.94 1.00 2016 167 115 10 TRUE 0.02
colorectal cancer KRAS_G13D ERBB4 96 60 Female 0.77 0.20 1.32 1317.83 1.00 1012 86 50 10 TRUE 2.20
colorectal cancer KRAS_G13D ERBB4 98 78 Male 0.74 0.18 1.28 1327.97 1.00 1211 88 68 10 TRUE 2.14
colorectal cancer KRAS_G13D ERBB4 194 138 Sex:overall 0.75 0.06 1.36 1326.69 1.00 2223 174 118 20 TRUE 1.54
colorectal cancer KRAS_G13D MDC1 84 27 Female 0.18 -1.89 1.53 113.60 1.03 907 83 26 1 FALSE 0.08
colorectal cancer KRAS_G13D MDC1 90 38 Male 1.05 0.25 1.88 147.51 1.02 1091 81 29 9 FALSE 1.76
colorectal cancer KRAS_G13D MDC1 174 65 Sex:overall 0.58 -1.15 1.70 210.96 1.01 1998 164 55 10 FALSE 0.35
colorectal cancer KRAS_G13D RECQL4 84 30 Female -0.11 -1.18 0.88 505.81 1.01 908 81 27 3 TRUE 0.08
colorectal cancer KRAS_G13D RECQL4 87 51 Male -0.19 -1.19 0.68 614.97 1.01 1075 84 48 3 TRUE 0.16
colorectal cancer KRAS_G13D RECQL4 171 81 Sex:overall -0.16 -1.33 0.90 981.71 1.00 1983 165 75 6 TRUE 0.11
colorectal cancer KRAS_G13D MED12 90 54 Female 0.51 -0.25 1.17 422.97 1.01 921 83 47 7 TRUE 0.80
colorectal cancer KRAS_G13D MED12 87 54 Male 0.50 -0.22 1.17 418.94 1.01 1106 81 48 6 TRUE 0.78
colorectal cancer KRAS_G13D MED12 177 108 Sex:overall 0.50 -0.30 1.24 570.81 1.01 2027 164 95 13 TRUE 0.68
colorectal cancer KRAS_G13D ERCC5 84 31 Female -0.15 -1.27 0.85 1082.47 1.00 910 81 28 3 TRUE 0.11
colorectal cancer KRAS_G13D ERCC5 87 27 Male -0.32 -1.74 0.77 1397.62 1.00 1088 86 26 1 TRUE 0.22
colorectal cancer KRAS_G13D ERCC5 171 58 Sex:overall -0.23 -1.50 0.89 1066.05 1.00 1998 167 54 4 TRUE 0.15
colorectal cancer KRAS_G13D PIK3CD 84 34 Female -0.17 -1.38 0.73 93.75 1.03 903 82 32 2 FALSE 0.12
colorectal cancer KRAS_G13D PIK3CD 87 35 Male -0.08 -1.23 0.83 131.93 1.03 1086 84 32 3 FALSE 0.06
colorectal cancer KRAS_G13D PIK3CD 171 69 Sex:overall -0.12 -1.32 0.82 116.50 1.03 1989 166 64 5 FALSE 0.08
colorectal cancer KRAS_G13D BRCA1 87 28 Female 0.93 0.00 1.63 883.22 1.00 942 83 24 4 TRUE 1.61
colorectal cancer KRAS_G13D BRCA1 93 51 Male 1.26 0.63 1.87 1424.29 1.00 1113 81 39 12 TRUE 4.13
colorectal cancer KRAS_G13D BRCA1 180 79 Sex:overall 1.08 0.10 1.96 1098.63 1.00 2055 164 63 16 TRUE 1.52
colorectal cancer KRAS_G13D RBM10 87 41 Female -0.78 -2.55 0.43 1031.58 1.00 930 86 40 1 FALSE 0.53
colorectal cancer KRAS_G13D RBM10 87 31 Male -0.30 -1.55 0.85 1102.09 1.00 1118 84 28 3 FALSE 0.20
colorectal cancer KRAS_G13D RBM10 174 72 Sex:overall -0.52 -2.15 0.85 1264.16 1.00 2048 170 68 4 FALSE 0.31
colorectal cancer KRAS_G13D TSC1 87 27 Female 0.59 -0.32 1.36 922.31 1.00 942 84 24 3 TRUE 0.85
colorectal cancer KRAS_G13D TSC1 88 40 Male 0.75 0.09 1.52 62.63 1.07 1121 81 33 7 TRUE 1.41
colorectal cancer KRAS_G13D TSC1 175 67 Sex:overall 0.65 -0.29 1.51 746.64 1.01 2063 165 57 10 TRUE 0.82
colorectal cancer KRAS_G13D FLCN 87 30 Female -1.09 -3.12 0.30 274.14 1.01 936 86 29 1 TRUE 0.65
colorectal cancer KRAS_G13D FLCN 87 24 Male -1.04 -3.13 0.45 284.80 1.00 1127 86 23 1 TRUE 0.60
colorectal cancer KRAS_G13D FLCN 174 54 Sex:overall -1.07 -3.21 0.46 303.52 1.00 2063 172 52 2 TRUE 0.60
colorectal cancer KRAS_G13D NF1 87 55 Female -0.37 -1.63 0.48 1326.11 1.00 921 85 53 2 TRUE 0.32
colorectal cancer KRAS_G13D NF1 90 87 Male 0.14 -0.57 0.86 746.87 1.00 1090 81 78 9 TRUE 0.14
colorectal cancer KRAS_G13D NF1 177 142 Sex:overall -0.12 -1.42 0.93 1460.46 1.00 2011 166 131 11 TRUE 0.07
colorectal cancer KRAS_G13D FLT1 87 30 Female 0.18 -0.80 1.00 1251.39 1.00 941 84 27 3 FALSE 0.15
colorectal cancer KRAS_G13D FLT1 87 52 Male 0.24 -0.62 1.02 863.70 1.00 1109 82 47 5 FALSE 0.24
colorectal cancer KRAS_G13D FLT1 174 82 Sex:overall 0.22 -0.86 1.25 1167.44 1.00 2050 166 74 8 FALSE 0.16
colorectal cancer KRAS_G13D RPTOR 87 32 Female 0.28 -0.66 1.09 998.75 1.01 936 83 28 4 FALSE 0.29
colorectal cancer KRAS_G13D RPTOR 89 38 Male 0.21 -0.81 0.99 1061.81 1.00 1115 86 35 3 FALSE 0.20
colorectal cancer KRAS_G13D RPTOR 176 70 Sex:overall 0.25 -0.80 1.12 987.06 1.00 2051 169 63 7 FALSE 0.22
colorectal cancer KRAS_G13D RASA1 87 30 Female -1.12 -5.04 0.52 731.73 1.00 937 87 30 0 FALSE 0.34
colorectal cancer KRAS_G13D RASA1 87 43 Male 0.12 -1.03 1.13 1095.40 1.00 1121 82 38 5 FALSE 0.09
colorectal cancer KRAS_G13D RASA1 174 73 Sex:overall -0.44 -2.90 1.06 1126.11 1.00 2058 169 68 5 FALSE 0.18
colorectal cancer KRAS_G13D EPHA5 87 58 Female -0.49 -1.46 0.25 1186.15 1.00 915 84 55 3 FALSE 0.58
colorectal cancer KRAS_G13D EPHA5 90 86 Male -0.41 -1.23 0.33 912.25 1.00 1081 85 81 5 FALSE 0.53
colorectal cancer KRAS_G13D EPHA5 177 144 Sex:overall -0.45 -1.43 0.44 1158.44 1.00 1996 169 136 8 FALSE 0.46
colorectal cancer KRAS_G13D AR 87 59 Female -0.37 -1.78 0.61 1061.44 1.01 913 85 57 2 TRUE 0.25
colorectal cancer KRAS_G13D AR 90 57 Male 0.57 -0.22 1.39 1102.57 1.00 1101 81 48 9 TRUE 0.77
colorectal cancer KRAS_G13D AR 177 116 Sex:overall 0.11 -1.38 1.44 1389.87 1.00 2014 166 105 11 TRUE 0.06
colorectal cancer KRAS_G13D GNAS 96 41 Female 0.97 0.16 1.62 1121.43 1.00 1027 89 34 7 TRUE 2.06
colorectal cancer KRAS_G13D GNAS 94 34 Male 1.09 0.36 1.79 1336.11 1.00 1242 87 27 7 TRUE 2.42
colorectal cancer KRAS_G13D GNAS 190 75 Sex:overall 1.02 0.01 1.92 1372.47 1.00 2269 176 61 14 TRUE 1.36
colorectal cancer KRAS_G13D ASXL2 87 20 Female -1.24 -5.51 0.71 1343.79 1.00 944 87 20 0 FALSE 0.33
colorectal cancer KRAS_G13D ASXL2 90 51 Male 0.72 -0.16 1.51 1464.66 1.00 1120 82 43 8 FALSE 1.03
colorectal cancer KRAS_G13D ASXL2 177 71 Sex:overall -0.20 -3.36 1.85 1292.28 1.00 2064 169 63 8 FALSE 0.06
colorectal cancer KRAS_G13D SF3B1 87 18 Female 0.71 -0.74 1.76 1568.03 1.00 949 85 16 2 TRUE 0.60
colorectal cancer KRAS_G13D SF3B1 95 52 Male 1.70 1.04 2.33 1581.97 1.00 1117 79 36 16 TRUE 6.85
colorectal cancer KRAS_G13D SF3B1 182 70 Sex:overall 1.18 -0.52 2.57 1471.95 1.00 2066 164 52 18 TRUE 0.90
colorectal cancer KRAS_G13D MLH1 96 20 Female 0.97 0.08 1.83 1464.25 1.00 1046 91 15 5 TRUE 1.67
colorectal cancer KRAS_G13D MLH1 94 36 Male 0.72 -0.23 1.51 1208.60 1.00 1241 90 32 4 TRUE 1.04
colorectal cancer KRAS_G13D MLH1 190 56 Sex:overall 0.82 -0.26 1.84 1377.32 1.00 2287 181 47 9 TRUE 0.83
colorectal cancer KRAS_G13D ROS1 87 32 Female -2.04 -7.63 0.45 1272.17 1.00 933 87 32 0 TRUE 0.47
colorectal cancer KRAS_G13D ROS1 93 71 Male 1.11 0.39 1.77 1451.34 1.00 1104 79 57 14 TRUE 2.88
colorectal cancer KRAS_G13D ROS1 180 103 Sex:overall -0.41 -4.08 2.00 1385.21 1.00 2037 166 89 14 TRUE 0.10
colorectal cancer KRAS_G13D PIK3R2 87 24 Female 0.37 -0.67 1.29 1243.83 1.00 945 84 21 3 FALSE 0.33
colorectal cancer KRAS_G13D PIK3R2 87 28 Male 0.38 -0.58 1.31 1484.87 1.00 1122 84 25 3 FALSE 0.36
colorectal cancer KRAS_G13D PIK3R2 174 52 Sex:overall 0.36 -0.75 1.34 1533.41 1.00 2067 168 46 6 FALSE 0.29
colorectal cancer KRAS_G13D FLT3 94 19 Female -0.22 -1.71 0.95 1002.14 1.00 1041 93 18 1 TRUE 0.13
colorectal cancer KRAS_G13D FLT3 95 33 Male -0.05 -1.23 1.01 700.23 1.00 1246 92 30 3 TRUE 0.03
colorectal cancer KRAS_G13D FLT3 189 52 Sex:overall -0.13 -1.57 1.09 895.02 1.00 2287 185 48 4 TRUE 0.07
colorectal cancer KRAS_G13D MSH2 88 34 Female 0.14 -0.78 0.91 1021.25 1.00 940 85 31 3 TRUE 0.13
colorectal cancer KRAS_G13D MSH2 89 49 Male 0.21 -0.61 0.94 1113.93 1.00 1113 84 44 5 TRUE 0.22
colorectal cancer KRAS_G13D MSH2 177 83 Sex:overall 0.16 -0.84 1.04 1206.43 1.00 2053 169 75 8 TRUE 0.13
colorectal cancer KRAS_G13D AXL 87 30 Female 0.29 -1.21 1.31 1131.33 1.00 937 85 28 2 FALSE 0.19
colorectal cancer KRAS_G13D AXL 91 58 Male 1.22 0.53 1.89 1243.78 1.00 1110 78 45 13 FALSE 3.25
colorectal cancer KRAS_G13D AXL 178 88 Sex:overall 0.75 -0.79 2.03 1444.35 1.00 2047 163 73 15 FALSE 0.51
colorectal cancer KRAS_G13D PIK3CG 88 39 Female -0.36 -1.53 0.60 942.74 1.00 927 86 37 2 FALSE 0.30
colorectal cancer KRAS_G13D PIK3CG 88 68 Male -0.18 -1.08 0.70 782.52 1.00 1095 83 63 5 FALSE 0.15
colorectal cancer KRAS_G13D PIK3CG 176 107 Sex:overall -0.28 -1.50 0.73 1163.40 1.00 2022 169 100 7 FALSE 0.21
colorectal cancer KRAS_G13D MAP2K4 87 28 Female 0.37 -0.75 1.34 441.84 1.01 938 85 26 2 TRUE 0.33
colorectal cancer KRAS_G13D MAP2K4 88 35 Male 0.64 -0.23 1.51 389.19 1.01 1118 82 29 6 TRUE 0.85
colorectal cancer KRAS_G13D MAP2K4 175 63 Sex:overall 0.52 -0.56 1.53 592.92 1.00 2056 167 55 8 TRUE 0.48
colorectal cancer KRAS_G13D EGFR 94 28 Female -0.29 -1.65 0.74 700.36 1.00 1034 93 27 1 TRUE 0.19
colorectal cancer KRAS_G13D EGFR 95 38 Male -0.01 -1.11 0.97 766.40 1.00 1238 91 34 4 TRUE 0.01
colorectal cancer KRAS_G13D EGFR 189 66 Sex:overall -0.15 -1.35 0.90 788.10 1.00 2272 184 61 5 TRUE 0.10
colorectal cancer KRAS_G13D ARID1B 87 70 Female -0.12 -0.98 0.58 867.70 1.00 908 83 66 4 TRUE 0.12
colorectal cancer KRAS_G13D ARID1B 87 70 Male 0.09 -0.66 0.84 1345.43 1.00 1095 80 63 7 TRUE 0.09
colorectal cancer KRAS_G13D ARID1B 174 140 Sex:overall -0.01 -0.92 0.83 1173.53 1.00 2003 163 129 11 TRUE 0.01
colorectal cancer KRAS_G13D ARID5B 87 20 Female -1.21 -4.90 0.52 923.27 1.00 944 87 20 0 FALSE 0.37
colorectal cancer KRAS_G13D ARID5B 88 48 Male -0.15 -1.36 0.85 1172.14 1.00 1114 84 44 4 FALSE 0.10
colorectal cancer KRAS_G13D ARID5B 175 68 Sex:overall -0.64 -3.09 1.14 1369.01 1.00 2058 171 64 4 FALSE 0.25
colorectal cancer KRAS_G13D BRAF 94 128 Female -1.14 -2.11 -0.36 1306.96 1.00 940 91 125 3 TRUE 1.94
colorectal cancer KRAS_G13D BRAF 94 125 Male -0.97 -1.80 -0.16 1479.46 1.00 1155 89 120 5 TRUE 1.72
colorectal cancer KRAS_G13D BRAF 188 253 Sex:overall -1.05 -2.02 -0.18 1405.70 1.00 2095 180 245 8 TRUE 1.50
colorectal cancer KRAS_G13D B2M 87 69 Female 0.19 -0.55 0.87 427.70 1.02 894 82 64 5 FALSE 0.24
colorectal cancer KRAS_G13D B2M 90 70 Male 0.43 -0.02 1.23 3.25 1.35 1076 79 59 11 FALSE 0.62
colorectal cancer KRAS_G13D B2M 177 139 Sex:overall 0.30 -0.48 1.10 14.49 1.07 1970 161 123 16 FALSE 0.32
colorectal cancer KRAS_G13D TGFBR1 84 14 Female -0.89 -5.51 0.90 1147.93 1.00 920 84 14 0 FALSE 0.23
colorectal cancer KRAS_G13D TGFBR1 88 37 Male 0.41 -0.74 1.39 1399.69 1.00 1087 83 32 5 FALSE 0.35
colorectal cancer KRAS_G13D TGFBR1 172 51 Sex:overall -0.16 -2.81 1.48 1032.89 1.01 2007 167 46 5 FALSE 0.05
colorectal cancer KRAS_G13D TET2 87 31 Female 0.16 -1.18 1.06 1300.17 1.00 939 85 29 2 TRUE 0.11
colorectal cancer KRAS_G13D TET2 91 60 Male 0.64 -0.12 1.36 1274.20 1.00 1104 82 51 9 TRUE 1.05
colorectal cancer KRAS_G13D TET2 178 91 Sex:overall 0.40 -0.96 1.47 1579.25 1.00 2043 167 80 11 TRUE 0.29
colorectal cancer KRAS_G13D PDGFRB 87 24 Female 0.68 -0.35 1.51 1477.81 1.00 942 84 21 3 TRUE 0.82
colorectal cancer KRAS_G13D PDGFRB 87 28 Male 0.81 -0.13 1.66 1296.37 1.00 1124 82 23 5 TRUE 1.18
colorectal cancer KRAS_G13D PDGFRB 174 52 Sex:overall 0.76 -0.24 1.72 1396.61 1.00 2066 166 44 8 TRUE 0.88
colorectal cancer KRAS_G13D CARD11 89 49 Female 0.20 -0.62 0.87 777.11 1.00 919 84 44 5 FALSE 0.22
colorectal cancer KRAS_G13D CARD11 88 79 Male 0.23 -0.49 0.87 1012.08 1.00 1084 81 72 7 FALSE 0.29
colorectal cancer KRAS_G13D CARD11 177 128 Sex:overall 0.21 -0.72 1.04 1246.89 1.00 2003 165 116 12 FALSE 0.19
colorectal cancer KRAS_G13D DNMT3A 88 24 Female 0.37 -0.67 1.26 609.96 1.01 945 85 21 3 TRUE 0.35
colorectal cancer KRAS_G13D DNMT3A 87 32 Male 0.36 -0.62 1.23 501.30 1.02 1120 84 29 3 TRUE 0.35
colorectal cancer KRAS_G13D DNMT3A 175 56 Sex:overall 0.35 -0.77 1.32 480.79 1.01 2065 169 50 6 TRUE 0.30
colorectal cancer KRAS_G13D MSH6 87 43 Female -0.44 -2.16 0.54 1157.32 1.00 926 86 42 1 TRUE 0.28
colorectal cancer KRAS_G13D MSH6 89 57 Male 0.20 -0.73 1.07 1349.77 1.00 1108 82 50 7 TRUE 0.19
colorectal cancer KRAS_G13D MSH6 176 100 Sex:overall -0.12 -1.60 0.99 1339.67 1.00 2034 168 92 8 TRUE 0.07
colorectal cancer KRAS_G13D SOX9 87 125 Female 0.55 0.11 1.01 1343.74 1.00 865 71 109 16 FALSE 1.77
colorectal cancer KRAS_G13D SOX9 89 139 Male 0.53 0.05 0.98 1264.04 1.00 1034 74 124 15 FALSE 1.64
colorectal cancer KRAS_G13D SOX9 176 264 Sex:overall 0.53 -0.02 1.02 1234.67 1.00 1899 145 233 31 FALSE 1.28
colorectal cancer KRAS_G13D ETV1 85 23 Female 0.82 -0.13 1.59 438.98 1.01 914 81 19 4 TRUE 1.29
colorectal cancer KRAS_G13D ETV1 87 29 Male 0.79 -0.14 1.58 457.03 1.01 1092 83 25 4 TRUE 1.27
colorectal cancer KRAS_G13D ETV1 172 52 Sex:overall 0.82 -0.21 1.66 605.65 1.01 2006 164 44 8 TRUE 1.12
colorectal cancer KRAS_G13D ARAF 88 30 Female -0.02 -1.32 0.96 1415.79 1.00 938 86 28 2 FALSE 0.01
colorectal cancer KRAS_G13D ARAF 87 25 Male 0.16 -0.98 1.22 1413.61 1.00 1126 84 22 3 FALSE 0.11
colorectal cancer KRAS_G13D ARAF 175 55 Sex:overall 0.04 -1.34 1.19 1415.47 1.00 2064 170 50 5 FALSE 0.02
colorectal cancer KRAS_G13D SMAD2 88 43 Female 0.39 -0.40 1.06 1195.36 1.00 927 84 39 4 TRUE 0.51
colorectal cancer KRAS_G13D SMAD2 88 59 Male 0.53 -0.18 1.18 1160.68 1.00 1102 80 51 8 TRUE 0.90
colorectal cancer KRAS_G13D SMAD2 176 102 Sex:overall 0.46 -0.38 1.25 1333.09 1.00 2029 164 90 12 TRUE 0.52
colorectal cancer KRAS_G13D JUN 84 32 Female -0.69 -2.37 0.50 1495.58 1.00 904 83 31 1 FALSE 0.46
colorectal cancer KRAS_G13D JUN 87 21 Male -0.34 -1.86 0.97 1383.37 1.00 1097 85 19 2 FALSE 0.20
colorectal cancer KRAS_G13D JUN 171 53 Sex:overall -0.51 -2.21 0.95 1522.88 1.00 2001 168 50 3 FALSE 0.27
colorectal cancer KRAS_G13D DNMT3B 84 25 Female -0.11 -1.28 0.82 1073.65 1.00 912 82 23 2 FALSE 0.08
colorectal cancer KRAS_G13D DNMT3B 87 39 Male -0.08 -1.20 0.80 1069.85 1.00 1084 84 36 3 FALSE 0.06
colorectal cancer KRAS_G13D DNMT3B 171 64 Sex:overall -0.10 -1.26 0.89 1156.60 1.00 1996 166 59 5 FALSE 0.07
colorectal cancer KRAS_G13D FGFR1 94 21 Female -1.15 -4.04 0.37 512.20 1.00 1038 94 21 0 TRUE 0.49
colorectal cancer KRAS_G13D FGFR1 94 30 Male -0.79 -2.69 0.63 541.09 1.00 1246 92 28 2 TRUE 0.45
colorectal cancer KRAS_G13D FGFR1 188 51 Sex:overall -0.96 -3.35 0.56 451.84 1.00 2284 186 49 2 TRUE 0.47
colorectal cancer KRAS_G13D MITF 87 22 Female -0.24 -1.75 0.84 1373.25 1.00 942 86 21 1 FALSE 0.15
colorectal cancer KRAS_G13D MITF 87 30 Male -0.08 -1.45 0.99 1348.96 1.00 1120 84 27 3 FALSE 0.05
colorectal cancer KRAS_G13D MITF 174 52 Sex:overall -0.15 -1.63 0.98 1233.15 1.00 2062 170 48 4 FALSE 0.09
colorectal cancer KRAS_G13D SH2B3 78 18 Female -0.36 -1.91 0.97 1400.23 1.00 862 76 16 2 FALSE 0.21
colorectal cancer KRAS_G13D SH2B3 79 38 Male -0.69 -2.50 0.55 1357.42 1.00 1021 78 37 1 FALSE 0.43
colorectal cancer KRAS_G13D SH2B3 157 56 Sex:overall -0.52 -2.31 0.84 1346.79 1.00 1883 154 53 3 FALSE 0.29
colorectal cancer KRAS_G13D GLI1 78 32 Female 0.03 -1.05 0.93 898.79 1.00 850 76 30 2 FALSE 0.02
colorectal cancer KRAS_G13D GLI1 81 55 Male 0.24 -0.61 1.01 780.25 1.00 1008 75 49 6 FALSE 0.24
colorectal cancer KRAS_G13D GLI1 159 87 Sex:overall 0.12 -0.97 1.07 1165.95 1.00 1858 151 79 8 FALSE 0.08
colorectal cancer KRAS_G13D ZFHX3 79 96 Female -0.54 -1.71 0.26 1264.67 1.00 810 76 93 3 FALSE 0.54
colorectal cancer KRAS_G13D ZFHX3 83 130 Male 0.16 -0.46 0.79 901.68 1.00 973 70 117 13 FALSE 0.20
colorectal cancer KRAS_G13D ZFHX3 162 226 Sex:overall -0.19 -1.60 0.93 1121.86 1.00 1783 146 210 16 FALSE 0.12
colorectal cancer KRAS_G13D MST1R 75 28 Female -0.21 -1.52 0.77 733.79 1.00 827 74 27 1 FALSE 0.14
colorectal cancer KRAS_G13D MST1R 79 45 Male 0.11 -1.05 1.01 232.72 1.01 987 74 40 5 FALSE 0.08
colorectal cancer KRAS_G13D MST1R 154 73 Sex:overall -0.05 -1.26 1.00 531.75 1.01 1814 148 67 6 FALSE 0.03
colorectal cancer KRAS_G13D MGA 78 50 Female -0.19 -1.71 0.82 791.57 1.00 835 76 48 2 FALSE 0.11
colorectal cancer KRAS_G13D MGA 83 73 Male 0.85 0.12 1.56 566.10 1.00 999 70 60 13 FALSE 1.70
colorectal cancer KRAS_G13D MGA 161 123 Sex:overall 0.34 -1.39 1.69 1346.38 1.00 1834 146 108 15 FALSE 0.19
colorectal cancer KRAS_G13D TCF3 75 31 Female 0.30 -0.61 1.11 1435.56 1.00 825 71 27 4 FALSE 0.31
colorectal cancer KRAS_G13D TCF3 79 37 Male 0.24 -0.73 1.03 1201.70 1.00 988 76 34 3 FALSE 0.23
colorectal cancer KRAS_G13D TCF3 154 68 Sex:overall 0.28 -0.72 1.11 1430.32 1.00 1813 147 61 7 FALSE 0.24
colorectal cancer KRAS_G13D KMT2B 51 87 Female 0.52 -0.08 1.06 1020.94 1.00 454 40 76 11 FALSE 1.09
colorectal cancer KRAS_G13D KMT2B 45 95 Male 0.53 -0.10 1.09 949.39 1.00 553 35 85 10 FALSE 1.08
colorectal cancer KRAS_G13D KMT2B 96 182 Sex:overall 0.52 -0.24 1.34 1264.64 1.00 1007 75 161 21 FALSE 0.70
colorectal cancer KRAS_G13D TCF7L2 79 124 Female 0.21 -0.31 0.72 1378.73 1.00 776 65 110 14 FALSE 0.37
colorectal cancer KRAS_G13D TCF7L2 82 175 Male 0.01 -0.57 0.50 1243.32 1.00 903 71 164 11 FALSE 0.01
colorectal cancer KRAS_G13D TCF7L2 161 299 Sex:overall 0.11 -0.55 0.76 1537.30 1.00 1679 136 274 25 FALSE 0.12
colorectal cancer KRAS_G13D MSH3 48 46 Female -0.04 -1.02 0.87 797.81 1.00 469 44 42 4 FALSE 0.03
colorectal cancer KRAS_G13D MSH3 43 43 Male -0.05 -1.12 0.78 911.02 1.00 569 40 40 3 FALSE 0.03
colorectal cancer KRAS_G13D MSH3 91 89 Sex:overall -0.05 -1.16 0.91 856.70 1.00 1038 84 82 7 FALSE 0.03
colorectal cancer KRAS_G13D ANKRD11 76 56 Female 0.09 -0.86 0.80 1360.50 1.00 804 72 52 4 FALSE 0.08
colorectal cancer KRAS_G13D ANKRD11 80 90 Male 0.34 -0.34 0.98 1396.12 1.00 965 70 80 10 FALSE 0.52
colorectal cancer KRAS_G13D ANKRD11 156 146 Sex:overall 0.22 -0.74 1.02 1388.01 1.00 1769 142 132 14 FALSE 0.21
colorectal cancer KRAS_G13D PGR 75 30 Female -0.20 -1.59 0.81 936.36 1.00 819 74 29 1 FALSE 0.13
colorectal cancer KRAS_G13D PGR 81 33 Male 0.07 -1.05 1.07 1215.76 1.00 995 77 29 4 FALSE 0.05
colorectal cancer KRAS_G13D PGR 156 63 Sex:overall -0.08 -1.40 0.94 1228.81 1.00 1814 151 58 5 FALSE 0.04
colorectal cancer KRAS_G13D PLCG2 76 31 Female 0.09 -0.99 0.91 417.39 1.01 819 74 29 2 FALSE 0.07
colorectal cancer KRAS_G13D PLCG2 81 54 Male 0.27 -0.51 1.04 891.95 1.01 977 75 48 6 FALSE 0.31
colorectal cancer KRAS_G13D PLCG2 157 85 Sex:overall 0.20 -0.93 1.17 1124.45 1.01 1796 149 77 8 FALSE 0.16
colorectal cancer KRAS_G13D POLD1 78 49 Female 0.13 -0.89 0.84 1378.02 1.00 842 75 46 3 TRUE 0.12
colorectal cancer KRAS_G13D POLD1 81 63 Male 0.37 -0.36 1.09 1385.29 1.00 1012 73 55 8 TRUE 0.50
colorectal cancer KRAS_G13D POLD1 159 112 Sex:overall 0.25 -0.68 1.05 1207.00 1.00 1854 148 101 11 TRUE 0.23
colorectal cancer KRAS_G13D INHBA 78 24 Female -2.08 -4.98 -0.30 1036.76 1.00 854 78 24 0 FALSE 0.99
colorectal cancer KRAS_G13D INHBA 79 30 Male -1.86 -4.76 -0.03 1002.84 1.00 1024 78 29 1 FALSE 0.95
colorectal cancer KRAS_G13D INHBA 157 54 Sex:overall -1.95 -4.78 -0.13 942.23 1.00 1878 156 53 1 FALSE 1.00
colorectal cancer KRAS_G13D PREX2 50 31 Female 0.44 -0.53 1.38 1405.88 1.00 481 45 26 5 FALSE 0.45
colorectal cancer KRAS_G13D PREX2 44 60 Male 0.13 -0.82 0.96 1418.02 1.00 556 40 56 4 FALSE 0.11
colorectal cancer KRAS_G13D PREX2 94 91 Sex:overall 0.27 -0.93 1.44 1403.52 1.00 1037 85 82 9 FALSE 0.19
colorectal cancer KRAS_G13D AMER1 89 85 Female 0.54 -0.04 1.06 1113.13 1.00 894 79 75 10 FALSE 1.30
colorectal cancer KRAS_G13D AMER1 90 84 Male 0.62 0.08 1.15 863.19 1.00 1077 78 72 12 FALSE 1.65
colorectal cancer KRAS_G13D AMER1 179 169 Sex:overall 0.58 -0.06 1.22 933.47 1.00 1971 157 147 22 FALSE 1.02
colorectal cancer KRAS_G13D HLA-A 76 26 Female 0.15 -0.99 1.04 365.33 1.02 826 74 24 2 FALSE 0.11
colorectal cancer KRAS_G13D HLA-A 79 25 Male 0.24 -0.89 1.15 555.24 1.02 1002 76 22 3 FALSE 0.19
colorectal cancer KRAS_G13D HLA-A 155 51 Sex:overall 0.20 -0.96 1.18 547.86 1.01 1828 150 46 5 FALSE 0.14
colorectal cancer KRAS_G13D EPHA7 78 39 Female -0.59 -2.00 0.39 1266.41 1.00 843 77 38 1 FALSE 0.48
colorectal cancer KRAS_G13D EPHA7 80 51 Male -0.34 -1.38 0.57 1335.04 1.00 1012 76 47 4 FALSE 0.30
colorectal cancer KRAS_G13D EPHA7 158 90 Sex:overall -0.48 -1.81 0.58 1263.35 1.00 1855 153 85 5 FALSE 0.37
colorectal cancer KRAS_G13D NCOA3 78 21 Female -0.30 -1.80 0.78 1395.87 1.00 858 77 20 1 TRUE 0.19
colorectal cancer KRAS_G13D NCOA3 79 35 Male -0.12 -1.36 0.88 1279.49 1.00 1023 76 32 3 TRUE 0.08
colorectal cancer KRAS_G13D NCOA3 157 56 Sex:overall -0.20 -1.61 0.98 1521.57 1.00 1881 153 52 4 TRUE 0.12
colorectal cancer KRAS_G13D SLX4 44 20 Female -0.42 -1.95 0.85 1376.58 1.00 457 42 18 2 FALSE 0.25
colorectal cancer KRAS_G13D SLX4 43 34 Male -0.63 -2.32 0.64 1360.66 1.00 544 42 33 1 FALSE 0.41
colorectal cancer KRAS_G13D SLX4 87 54 Sex:overall -0.53 -2.18 0.88 1549.73 1.00 1001 84 51 3 FALSE 0.30
colorectal cancer KRAS_G13D INPPL1 45 22 Female 0.47 -0.58 1.38 1146.06 1.00 460 42 19 3 FALSE 0.46
colorectal cancer KRAS_G13D INPPL1 44 51 Male 0.55 -0.38 1.30 968.39 1.00 538 38 45 6 FALSE 0.69
colorectal cancer KRAS_G13D INPPL1 89 73 Sex:overall 0.51 -0.70 1.71 1041.06 1.00 998 80 64 9 FALSE 0.38
melanoma NRAS_Q61K SPEN 26 26 Female -1.51 -5.26 0.26 1193.81 1.00 324 26 26 0 FALSE 0.56
melanoma NRAS_Q61K SPEN 37 91 Male -0.39 -1.49 0.55 1446.18 1.00 486 32 86 5 FALSE 0.34
melanoma NRAS_Q61K SPEN 63 117 Sex:overall -0.94 -3.48 0.91 1308.15 1.00 810 58 112 5 FALSE 0.41
melanoma NRAS_Q61K KMT2C 26 33 Female 0.20 -1.07 1.38 1572.03 1.00 309 22 29 4 FALSE 0.12
melanoma NRAS_Q61K KMT2C 35 116 Male -0.84 -2.02 0.14 1388.29 1.00 427 32 113 3 FALSE 0.86
melanoma NRAS_Q61K KMT2C 61 149 Sex:overall -0.35 -2.01 1.44 1368.38 1.00 736 54 142 7 FALSE 0.16
melanoma NRAS_Q61K TP53 27 63 Female 0.44 -0.28 1.20 1142.54 1.00 299 20 56 7 TRUE 0.61
melanoma NRAS_Q61K TP53 39 147 Male 0.30 -0.32 0.91 1191.65 1.00 440 28 136 11 TRUE 0.45
melanoma NRAS_Q61K TP53 66 210 Sex:overall 0.38 -0.50 1.29 1157.46 1.00 739 48 192 18 TRUE 0.37
melanoma NRAS_Q61K ATRX 27 71 Female -0.32 -1.40 0.67 1588.22 1.00 299 23 67 4 TRUE 0.26
melanoma NRAS_Q61K ATRX 37 37 Male -0.38 -1.75 0.85 1341.15 1.00 515 35 35 2 TRUE 0.24
melanoma NRAS_Q61K ATRX 64 108 Sex:overall -0.34 -2.08 1.34 1463.81 1.00 814 58 102 6 TRUE 0.16
melanoma NRAS_Q61K ATR 26 16 Female -1.21 -4.83 0.54 1302.02 1.00 332 26 16 0 FALSE 0.42
melanoma NRAS_Q61K ATR 37 49 Male -0.46 -1.92 0.73 1235.24 1.00 500 34 46 3 FALSE 0.31
melanoma NRAS_Q61K ATR 63 65 Sex:overall -0.80 -3.32 0.96 1408.23 1.00 832 60 62 3 FALSE 0.34
melanoma NRAS_Q61K PDGFRA 27 24 Female -0.87 -2.80 0.78 668.66 1.00 334 25 22 2 TRUE 0.48
melanoma NRAS_Q61K PDGFRA 38 54 Male -1.72 -5.17 0.10 414.11 1.00 508 38 54 0 TRUE 0.65
melanoma NRAS_Q61K PDGFRA 65 78 Sex:overall -1.21 -3.51 0.64 550.72 1.00 842 63 76 2 TRUE 0.61
melanoma NRAS_Q61K NSD1 26 15 Female -0.87 -2.73 0.78 743.87 1.00 332 25 14 1 FALSE 0.46
melanoma NRAS_Q61K NSD1 37 42 Male -1.04 -2.82 0.44 1064.36 1.00 506 36 41 1 FALSE 0.67
melanoma NRAS_Q61K NSD1 63 57 Sex:overall -0.97 -2.86 0.75 926.80 1.00 838 61 55 2 FALSE 0.51
melanoma NRAS_Q61K FLT4 26 24 Female -1.50 -4.85 0.10 1113.38 1.01 324 26 24 0 TRUE 0.59
melanoma NRAS_Q61K FLT4 37 69 Male -0.81 -2.19 0.36 1064.25 1.00 489 34 66 3 TRUE 0.68
melanoma NRAS_Q61K FLT4 63 93 Sex:overall -1.14 -3.51 0.43 934.16 1.01 813 60 90 3 TRUE 0.59
melanoma NRAS_Q61K PTPRD 26 54 Female -0.54 -1.75 0.64 1363.01 1.00 308 23 51 3 FALSE 0.42
melanoma NRAS_Q61K PTPRD 38 219 Male -0.96 -1.90 -0.17 1429.43 1.00 416 32 213 6 FALSE 1.53
melanoma NRAS_Q61K PTPRD 64 273 Sex:overall -0.74 -2.32 0.90 809.16 1.00 724 55 264 9 FALSE 0.46
melanoma NRAS_Q61K RET 27 14 Female -5.14 -12.14 -0.60 1443.97 1.00 339 27 14 0 TRUE 1.10
melanoma NRAS_Q61K RET 38 50 Male -5.21 -12.09 -1.10 1334.91 1.00 511 38 50 0 TRUE 1.17
melanoma NRAS_Q61K RET 65 64 Sex:overall -5.05 -12.00 -0.84 1479.29 1.00 850 65 64 0 TRUE 1.10
melanoma NRAS_Q61K PIK3C2G 25 39 Female -2.10 -6.37 -0.06 1319.16 1.00 303 25 39 0 FALSE 0.63
melanoma NRAS_Q61K PIK3C2G 37 157 Male -0.26 -1.08 0.55 1727.35 1.00 415 28 148 9 FALSE 0.27
melanoma NRAS_Q61K PIK3C2G 62 196 Sex:overall -1.10 -4.10 1.04 1303.23 1.00 718 53 187 9 FALSE 0.42
melanoma NRAS_Q61K CREBBP 26 15 Female -1.68 -5.38 0.37 1104.38 1.00 331 26 15 0 TRUE 0.56
melanoma NRAS_Q61K CREBBP 37 57 Male -1.09 -2.89 0.31 1413.55 1.00 498 35 55 2 TRUE 0.74
melanoma NRAS_Q61K CREBBP 63 72 Sex:overall -1.28 -3.82 0.77 1229.49 1.00 829 61 70 2 TRUE 0.58
melanoma NRAS_Q61K DOT1L 26 14 Female -1.46 -4.46 0.79 1239.18 1.00 335 25 13 1 FALSE 0.60
melanoma NRAS_Q61K DOT1L 37 43 Male -2.29 -6.01 -0.14 1203.68 1.00 504 37 43 0 FALSE 0.80
melanoma NRAS_Q61K DOT1L 63 57 Sex:overall -1.83 -4.99 0.52 1200.94 1.00 839 62 56 1 FALSE 0.71
melanoma NRAS_Q61K PTPRS 25 29 Female -1.07 -2.91 0.23 620.45 1.00 308 24 28 1 FALSE 0.71
melanoma NRAS_Q61K PTPRS 35 38 Male -1.09 -2.86 0.24 487.61 1.01 479 34 37 1 FALSE 0.74
melanoma NRAS_Q61K PTPRS 60 67 Sex:overall -1.08 -2.98 0.32 649.29 1.00 787 58 65 2 FALSE 0.69
melanoma NRAS_Q61K SMARCA4 26 24 Female -0.72 -2.22 0.54 1140.95 1.00 324 25 23 1 FALSE 0.53
melanoma NRAS_Q61K SMARCA4 37 48 Male -0.69 -2.12 0.45 1004.56 1.00 502 35 46 2 FALSE 0.56
melanoma NRAS_Q61K SMARCA4 63 72 Sex:overall -0.70 -2.19 0.52 961.87 1.00 826 60 69 3 FALSE 0.50
melanoma NRAS_Q61K PTPRT 28 101 Female 0.83 0.12 1.57 1518.72 1.00 290 15 88 13 FALSE 1.55
melanoma NRAS_Q61K PTPRT 41 271 Male 0.22 -0.38 0.85 1443.42 1.00 400 24 254 17 FALSE 0.32
melanoma NRAS_Q61K PTPRT 69 372 Sex:overall 0.52 -0.68 1.77 1391.57 1.00 690 39 342 30 FALSE 0.38
melanoma NRAS_Q61K HGF 26 16 Female 0.02 -1.64 1.54 1570.47 1.00 333 24 14 2 FALSE 0.01
melanoma NRAS_Q61K HGF 37 67 Male -0.68 -2.18 0.55 717.27 1.00 489 35 65 2 FALSE 0.50
melanoma NRAS_Q61K HGF 63 83 Sex:overall -0.31 -2.28 1.55 1298.52 1.00 822 59 79 4 FALSE 0.12
melanoma NRAS_Q61K ALK 28 43 Female -0.01 -1.09 1.07 431.79 1.01 322 23 38 5 TRUE 0.01
melanoma NRAS_Q61K ALK 38 85 Male -0.59 -1.97 0.41 674.22 1.00 486 36 83 2 TRUE 0.50
melanoma NRAS_Q61K ALK 66 128 Sex:overall -0.30 -1.64 0.82 972.27 1.00 808 59 121 7 TRUE 0.19
melanoma NRAS_Q61K BAP1 26 27 Female -1.30 -3.65 0.20 682.97 1.00 319 26 27 0 TRUE 0.61
melanoma NRAS_Q61K BAP1 37 39 Male -0.93 -2.67 0.38 619.42 1.00 508 35 37 2 TRUE 0.61
melanoma NRAS_Q61K BAP1 63 66 Sex:overall -1.08 -3.21 0.32 650.49 1.00 827 61 64 2 TRUE 0.62
melanoma NRAS_Q61K PTEN 27 29 Female 0.12 -0.98 1.05 1270.07 1.00 327 24 26 3 TRUE 0.09
melanoma NRAS_Q61K PTEN 38 50 Male 0.03 -1.02 0.88 1130.15 1.00 505 35 47 3 TRUE 0.02
melanoma NRAS_Q61K PTEN 65 79 Sex:overall 0.08 -1.01 1.07 1330.96 1.00 832 59 73 6 TRUE 0.05
melanoma NRAS_Q61K CTNNB1 27 21 Female 0.61 -0.38 1.47 1299.28 1.00 336 24 18 3 TRUE 0.72
melanoma NRAS_Q61K CTNNB1 39 37 Male 0.57 -0.38 1.42 1062.64 1.00 518 35 33 4 TRUE 0.69
melanoma NRAS_Q61K CTNNB1 66 58 Sex:overall 0.60 -0.43 1.56 1230.22 1.00 854 59 51 7 TRUE 0.64
melanoma NRAS_Q61K ARID1A 26 28 Female 0.21 -0.78 1.20 1115.11 1.00 323 23 25 3 TRUE 0.17
melanoma NRAS_Q61K ARID1A 38 61 Male 0.09 -0.94 0.98 1074.13 1.00 494 34 57 4 TRUE 0.07
melanoma NRAS_Q61K ARID1A 64 89 Sex:overall 0.15 -0.99 1.25 1041.33 1.00 817 57 82 7 TRUE 0.10
melanoma NRAS_Q61K IKZF1 26 32 Female -0.68 -2.01 0.51 1064.92 1.00 320 24 30 2 TRUE 0.54
melanoma NRAS_Q61K IKZF1 37 77 Male -0.88 -2.13 0.23 1096.74 1.00 491 35 75 2 TRUE 0.82
melanoma NRAS_Q61K IKZF1 63 109 Sex:overall -0.77 -2.10 0.59 1144.49 1.00 811 59 105 4 TRUE 0.56
melanoma NRAS_Q61K TERT 28 188 Female 1.71 0.86 2.74 1430.04 1.00 210 4 164 24 TRUE 3.37
melanoma NRAS_Q61K TERT 39 426 Male 0.71 -0.02 1.53 1461.16 1.00 226 10 397 29 TRUE 1.18
melanoma NRAS_Q61K TERT 67 614 Sex:overall 1.18 -0.38 2.73 1498.04 1.00 436 14 561 53 TRUE 0.88
melanoma NRAS_Q61K FAT1 26 46 Female 0.36 -0.59 1.36 1282.95 1.00 313 20 40 6 FALSE 0.32
melanoma NRAS_Q61K FAT1 37 103 Male -0.25 -1.26 0.54 1243.40 1.00 469 33 99 4 FALSE 0.23
melanoma NRAS_Q61K FAT1 63 149 Sex:overall 0.06 -1.28 1.41 1287.92 1.00 782 53 139 10 FALSE 0.03
melanoma NRAS_Q61K CIC 26 19 Female 0.13 -1.30 1.57 744.40 1.00 331 23 16 3 TRUE 0.07
melanoma NRAS_Q61K CIC 37 35 Male -0.98 -4.54 0.57 300.62 1.01 511 37 35 0 TRUE 0.34
melanoma NRAS_Q61K CIC 63 54 Sex:overall -0.41 -3.05 1.37 903.14 1.00 842 60 51 3 TRUE 0.15
melanoma NRAS_Q61K KDM6A 37 61 Male -5.89 -15.58 -1.15 1279.24 1.00 525 37 61 0 FALSE 0.91
melanoma NRAS_Q61K KDM6A 37 61 Sex:overall -4.40 -11.44 2.95 1448.57 1.00 525 37 61 0 FALSE 0.67
melanoma NRAS_Q61K POLE 26 22 Female 0.70 -0.27 1.59 1417.20 1.00 327 23 19 3 TRUE 0.86
melanoma NRAS_Q61K POLE 39 50 Male 0.70 -0.12 1.51 1161.49 1.00 502 33 44 6 TRUE 1.06
melanoma NRAS_Q61K POLE 65 72 Sex:overall 0.70 -0.26 1.71 1472.70 1.00 829 56 63 9 TRUE 0.76
melanoma NRAS_Q61K NOTCH2 25 11 Female 0.42 -1.26 2.08 1393.62 1.00 325 23 9 2 TRUE 0.21
melanoma NRAS_Q61K NOTCH2 35 54 Male -0.47 -1.91 0.72 1492.74 1.00 468 33 52 2 TRUE 0.31
melanoma NRAS_Q61K NOTCH2 60 65 Sex:overall -0.03 -2.19 1.97 1411.67 1.00 793 56 61 4 TRUE 0.01
melanoma NRAS_Q61K KMT2A 26 45 Female -0.18 -1.25 0.67 1059.34 1.00 314 23 42 3 FALSE 0.15
melanoma NRAS_Q61K KMT2A 38 95 Male -0.21 -1.15 0.58 1049.68 1.00 481 33 90 5 FALSE 0.20
melanoma NRAS_Q61K KMT2A 64 140 Sex:overall -0.19 -1.22 0.82 1448.44 1.00 795 56 132 8 FALSE 0.14
melanoma NRAS_Q61K PAK7 26 57 Female 0.13 -0.85 1.12 1329.28 1.00 287 20 51 6 FALSE 0.10
melanoma NRAS_Q61K PAK7 36 161 Male -0.86 -1.92 0.01 1385.78 1.00 406 32 157 4 FALSE 1.09
melanoma NRAS_Q61K PAK7 62 218 Sex:overall -0.35 -1.95 1.30 1490.76 1.00 693 52 208 10 FALSE 0.18
melanoma NRAS_Q61K BRCA2 26 23 Female 0.05 -1.41 1.47 1382.13 1.00 331 23 20 3 TRUE 0.02
melanoma NRAS_Q61K BRCA2 37 69 Male -1.11 -2.97 0.19 1332.75 1.00 490 36 68 1 TRUE 0.73
melanoma NRAS_Q61K BRCA2 63 92 Sex:overall -0.50 -2.44 1.41 1445.80 1.00 821 59 88 4 TRUE 0.23
melanoma NRAS_Q61K NOTCH3 26 27 Female -0.05 -1.43 1.09 1448.25 1.00 325 24 25 2 TRUE 0.03
melanoma NRAS_Q61K NOTCH3 38 103 Male 0.03 -0.80 0.75 1389.56 1.00 472 31 96 7 TRUE 0.02
melanoma NRAS_Q61K NOTCH3 64 130 Sex:overall -0.02 -1.63 1.44 1304.98 1.00 797 55 121 9 TRUE 0.01
melanoma NRAS_Q61K NOTCH4 25 32 Female -0.22 -1.56 0.93 1343.67 1.00 310 23 30 2 TRUE 0.14
melanoma NRAS_Q61K NOTCH4 36 116 Male -0.09 -0.94 0.68 1410.09 1.00 432 29 109 7 TRUE 0.08
melanoma NRAS_Q61K NOTCH4 61 148 Sex:overall -0.16 -1.73 1.31 1502.18 1.00 742 52 139 9 TRUE 0.08
melanoma NRAS_Q61K CDKN2A 28 39 Female 0.60 -0.29 1.49 1388.32 1.00 323 22 33 6 TRUE 0.71
melanoma NRAS_Q61K CDKN2A 39 90 Male 0.21 -0.57 0.95 1315.75 1.00 476 33 84 6 TRUE 0.21
melanoma NRAS_Q61K CDKN2A 67 129 Sex:overall 0.39 -0.81 1.56 1366.72 1.00 799 55 117 12 TRUE 0.29
melanoma NRAS_Q61K EPHB1 26 13 Female -1.23 -4.61 0.65 1214.96 1.00 335 26 13 0 FALSE 0.41
melanoma NRAS_Q61K EPHB1 37 53 Male -0.47 -2.00 0.70 1311.31 1.00 497 34 50 3 FALSE 0.31
melanoma NRAS_Q61K EPHB1 63 66 Sex:overall -0.82 -3.37 1.09 1292.14 1.00 832 60 63 3 FALSE 0.34
melanoma NRAS_Q61K IL7R 26 28 Female -0.96 -2.62 0.30 1472.55 1.00 324 25 27 1 FALSE 0.77
melanoma NRAS_Q61K IL7R 37 66 Male -0.95 -2.29 0.18 1377.90 1.00 492 35 64 2 FALSE 0.88
melanoma NRAS_Q61K IL7R 63 94 Sex:overall -0.94 -2.50 0.39 1315.71 1.00 816 60 91 3 FALSE 0.72
melanoma NRAS_Q61K ATM 27 20 Female -0.70 -2.50 0.61 931.59 1.01 335 26 19 1 TRUE 0.45
melanoma NRAS_Q61K ATM 38 58 Male -0.75 -2.29 0.34 547.67 1.01 500 36 56 2 TRUE 0.61
melanoma NRAS_Q61K ATM 65 78 Sex:overall -0.72 -2.51 0.64 1001.93 1.01 835 62 75 3 TRUE 0.43
melanoma NRAS_Q61K MAP2K1 26 14 Female 0.10 -1.52 1.42 1453.81 1.00 334 25 13 1 TRUE 0.05
melanoma NRAS_Q61K MAP2K1 37 44 Male 0.26 -0.85 1.23 1184.41 1.00 504 33 40 4 TRUE 0.20
melanoma NRAS_Q61K MAP2K1 63 58 Sex:overall 0.17 -1.36 1.51 1434.28 1.00 838 58 53 5 TRUE 0.09
melanoma NRAS_Q61K RB1 27 18 Female 0.64 -0.45 1.61 1009.98 1.00 341 24 15 3 TRUE 0.67
melanoma NRAS_Q61K RB1 38 33 Male 0.52 -0.53 1.38 797.24 1.00 525 35 30 3 TRUE 0.53
melanoma NRAS_Q61K RB1 65 51 Sex:overall 0.57 -0.55 1.57 964.85 1.00 866 59 45 6 TRUE 0.54
melanoma NRAS_Q61K KMT2D 27 57 Female 0.70 -0.16 1.59 1345.99 1.00 310 19 49 8 FALSE 0.94
melanoma NRAS_Q61K KMT2D 40 161 Male 0.12 -0.63 0.75 1557.33 1.00 452 30 151 10 FALSE 0.13
melanoma NRAS_Q61K KMT2D 67 218 Sex:overall 0.39 -0.77 1.63 1541.07 1.00 762 49 200 18 FALSE 0.26
melanoma NRAS_Q61K APC 27 33 Female 0.00 -1.07 0.97 1453.20 1.00 330 24 30 3 TRUE 0.00
melanoma NRAS_Q61K APC 38 93 Male -0.15 -1.06 0.63 1458.50 1.00 489 33 88 5 TRUE 0.13
melanoma NRAS_Q61K APC 65 126 Sex:overall -0.09 -1.36 1.10 1310.81 1.00 819 57 118 8 TRUE 0.05
melanoma NRAS_Q61K ARID2 27 45 Female 0.87 0.00 1.81 1231.62 1.00 315 19 37 8 FALSE 1.23
melanoma NRAS_Q61K ARID2 38 105 Male 0.19 -0.75 0.93 1107.74 1.01 487 32 99 6 FALSE 0.19
melanoma NRAS_Q61K ARID2 65 150 Sex:overall 0.54 -0.74 1.80 1401.67 1.00 802 51 136 14 FALSE 0.40
melanoma NRAS_Q61K MTOR 37 43 Male -1.54 -4.43 0.31 1360.39 1.00 506 36 42 1 TRUE 0.71
melanoma NRAS_Q61K MTOR 37 43 Sex:overall -1.25 -5.67 3.78 1412.19 1.00 506 36 42 1 TRUE 0.23
melanoma NRAS_Q61K NOTCH1 27 13 Female -0.22 -1.94 1.24 1533.91 1.00 343 26 12 1 TRUE 0.11
melanoma NRAS_Q61K NOTCH1 38 54 Male -0.25 -1.50 0.76 1449.12 1.00 509 35 51 3 TRUE 0.18
melanoma NRAS_Q61K NOTCH1 65 67 Sex:overall -0.21 -1.90 1.50 1370.97 1.00 852 61 63 4 TRUE 0.09
melanoma NRAS_Q61K NTRK1 37 42 Male -1.47 -4.34 0.40 1528.53 1.00 507 36 41 1 TRUE 0.66
melanoma NRAS_Q61K NTRK1 37 42 Sex:overall -1.21 -5.74 4.10 1511.33 1.00 507 36 41 1 TRUE 0.23
melanoma NRAS_Q61K SETD2 26 20 Female -0.22 -1.67 1.16 1403.94 1.00 333 24 18 2 FALSE 0.12
melanoma NRAS_Q61K SETD2 37 69 Male -0.74 -2.19 0.38 1511.71 1.00 488 35 67 2 FALSE 0.61
melanoma NRAS_Q61K SETD2 63 89 Sex:overall -0.45 -2.20 1.30 1413.65 1.00 821 59 85 4 FALSE 0.23
melanoma NRAS_Q61K PBRM1 26 15 Female -0.15 -1.82 1.26 1397.29 1.00 334 25 14 1 TRUE 0.07
melanoma NRAS_Q61K PBRM1 37 59 Male -0.02 -1.15 0.95 1536.52 1.00 499 33 55 4 TRUE 0.01
melanoma NRAS_Q61K PBRM1 63 74 Sex:overall -0.10 -1.76 1.38 1510.41 1.00 833 58 69 5 TRUE 0.04
melanoma NRAS_Q61K EPHA3 26 20 Female 0.18 -1.19 1.36 1540.36 1.00 330 24 18 2 FALSE 0.11
melanoma NRAS_Q61K EPHA3 37 87 Male 0.10 -0.86 0.90 1485.29 1.00 484 31 81 6 FALSE 0.08
melanoma NRAS_Q61K EPHA3 63 107 Sex:overall 0.16 -1.44 1.71 1608.29 1.00 814 55 99 8 FALSE 0.08
melanoma NRAS_Q61K KIT 27 31 Female -1.92 -4.59 -0.11 846.31 1.00 325 26 30 1 TRUE 0.98
melanoma NRAS_Q61K KIT 38 34 Male -2.16 -5.14 -0.25 801.45 1.00 521 38 34 0 TRUE 0.98
melanoma NRAS_Q61K KIT 65 65 Sex:overall -2.01 -4.81 -0.02 743.27 1.00 846 64 64 1 TRUE 0.97
melanoma NRAS_Q61K KDR 27 40 Female -1.14 -2.65 0.18 1113.43 1.00 322 25 38 2 TRUE 0.95
melanoma NRAS_Q61K KDR 38 92 Male -1.53 -3.19 -0.26 1176.62 1.00 481 37 91 1 TRUE 1.41
melanoma NRAS_Q61K KDR 65 132 Sex:overall -1.31 -3.02 0.20 1171.04 1.00 803 62 129 3 TRUE 0.96
melanoma NRAS_Q61K CSF1R 38 48 Male 0.23 -0.96 1.25 1507.49 1.00 515 34 44 4 TRUE 0.16
melanoma NRAS_Q61K CSF1R 38 48 Sex:overall 0.20 -3.94 4.05 1196.54 1.00 515 34 44 4 TRUE 0.04
melanoma NRAS_Q61K PTCH1 37 46 Male -1.64 -4.33 0.22 1275.33 1.00 502 36 45 1 TRUE 0.76
melanoma NRAS_Q61K PTCH1 37 46 Sex:overall -1.37 -5.51 3.55 1224.12 1.00 502 36 45 1 TRUE 0.28
melanoma NRAS_Q61K TET1 25 11 Female 0.43 -1.20 1.96 1548.48 1.00 326 23 9 2 FALSE 0.22
melanoma NRAS_Q61K TET1 35 44 Male -0.21 -1.64 0.93 1255.81 1.00 478 33 42 2 FALSE 0.13
melanoma NRAS_Q61K TET1 60 55 Sex:overall 0.10 -1.77 1.97 1235.39 1.00 804 56 51 4 FALSE 0.04
melanoma NRAS_Q61K FGFR2 27 19 Female -1.16 -3.35 0.53 1346.93 1.00 336 26 18 1 TRUE 0.64
melanoma NRAS_Q61K FGFR2 38 66 Male -1.46 -3.38 -0.03 1269.34 1.00 503 37 65 1 TRUE 1.09
melanoma NRAS_Q61K FGFR2 65 85 Sex:overall -1.28 -3.54 0.50 1223.87 1.00 839 63 83 2 TRUE 0.69
melanoma NRAS_Q61K TBX3 38 51 Male -0.29 -1.71 0.84 1446.54 1.00 504 35 48 3 FALSE 0.18
melanoma NRAS_Q61K TBX3 38 51 Sex:overall -0.28 -4.26 3.82 1430.54 1.00 504 35 48 3 FALSE 0.05
melanoma NRAS_Q61K DICER1 26 21 Female -1.79 -4.42 0.08 1027.72 1.00 329 25 20 1 TRUE 0.91
melanoma NRAS_Q61K DICER1 37 41 Male -2.10 -5.40 -0.24 970.76 1.00 512 37 41 0 TRUE 0.97
melanoma NRAS_Q61K DICER1 63 62 Sex:overall -1.93 -4.69 -0.02 1065.75 1.00 841 62 61 1 TRUE 0.97
melanoma NRAS_Q61K NTRK3 26 24 Female -1.04 -2.79 0.51 1458.54 1.00 327 25 23 1 FALSE 0.67
melanoma NRAS_Q61K NTRK3 37 82 Male -1.15 -2.71 0.04 1551.82 1.00 481 35 80 2 FALSE 1.01
melanoma NRAS_Q61K NTRK3 63 106 Sex:overall -1.06 -2.93 0.67 1492.17 1.00 808 60 103 3 FALSE 0.64
melanoma NRAS_Q61K GRIN2A 26 50 Female -0.04 -1.14 0.98 1454.19 1.00 312 22 46 4 FALSE 0.03
melanoma NRAS_Q61K GRIN2A 40 251 Male -0.55 -1.27 0.16 1605.92 1.00 403 30 241 10 FALSE 0.89
melanoma NRAS_Q61K GRIN2A 66 301 Sex:overall -0.31 -2.05 1.40 1689.98 1.00 715 52 287 14 FALSE 0.14
melanoma NRAS_Q61K BRD4 26 17 Female 0.17 -1.57 1.30 1255.61 1.00 331 25 16 1 FALSE 0.09
melanoma NRAS_Q61K BRD4 37 45 Male 0.47 -0.46 1.41 1010.41 1.01 511 32 40 5 FALSE 0.48
melanoma NRAS_Q61K BRD4 63 62 Sex:overall 0.32 -1.14 1.50 1250.50 1.00 842 57 56 6 FALSE 0.20
melanoma NRAS_Q61K ASXL1 26 13 Female 0.29 -1.07 1.60 1444.38 1.00 335 24 11 2 TRUE 0.17
melanoma NRAS_Q61K ASXL1 37 38 Male -0.03 -1.47 1.10 1409.28 1.00 512 35 36 2 TRUE 0.02
melanoma NRAS_Q61K ASXL1 63 51 Sex:overall 0.15 -1.42 1.60 1209.83 1.00 847 59 47 4 TRUE 0.07
melanoma NRAS_Q61K EP300 26 13 Female -1.35 -4.29 0.92 1423.99 1.00 338 25 12 1 TRUE 0.50
melanoma NRAS_Q61K EP300 37 56 Male -2.69 -6.95 -0.44 1370.34 1.00 499 37 56 0 TRUE 0.98
melanoma NRAS_Q61K EP300 63 69 Sex:overall -1.91 -5.02 0.79 1469.16 1.00 837 62 68 1 TRUE 0.73
melanoma NRAS_Q61K ERBB4 27 50 Female -1.06 -2.50 0.19 1514.01 1.00 315 25 48 2 TRUE 0.97
melanoma NRAS_Q61K ERBB4 38 143 Male -1.25 -2.40 -0.29 1295.76 1.00 456 35 140 3 TRUE 1.66
melanoma NRAS_Q61K ERBB4 65 193 Sex:overall -1.12 -2.60 0.24 1499.31 1.00 771 60 188 5 TRUE 0.92
melanoma NRAS_Q61K MDC1 25 18 Female -0.51 -2.27 0.93 1349.92 1.00 319 24 17 1 FALSE 0.27
melanoma NRAS_Q61K MDC1 35 65 Male -0.50 -1.77 0.55 1567.40 1.00 463 32 62 3 FALSE 0.38
melanoma NRAS_Q61K MDC1 60 83 Sex:overall -0.48 -2.31 1.13 1409.84 1.00 782 56 79 4 FALSE 0.22
melanoma NRAS_Q61K GNAQ 27 25 Female -0.81 -2.66 0.80 23.32 1.14 329 26 24 1 TRUE 0.41
melanoma NRAS_Q61K GNAQ 38 34 Male -0.84 -2.87 0.80 21.10 1.16 519 37 33 1 TRUE 0.43
melanoma NRAS_Q61K GNAQ 65 59 Sex:overall -0.82 -2.77 0.79 24.37 1.14 848 63 57 2 TRUE 0.41
melanoma NRAS_Q61K MED12 26 29 Female -0.89 -2.82 0.58 1178.61 1.00 327 25 28 1 TRUE 0.51
melanoma NRAS_Q61K MED12 37 24 Male -0.86 -2.84 0.60 1329.51 1.00 522 36 23 1 TRUE 0.48
melanoma NRAS_Q61K MED12 63 53 Sex:overall -0.88 -2.87 0.76 1332.81 1.00 849 61 51 2 TRUE 0.45
melanoma NRAS_Q61K NF1 26 79 Female -2.62 -4.65 -0.99 1452.24 1.00 285 25 78 1 TRUE 2.32
melanoma NRAS_Q61K NF1 37 218 Male -2.87 -4.75 -1.48 1334.75 1.00 406 36 217 1 TRUE 3.13
melanoma NRAS_Q61K NF1 63 297 Sex:overall -2.71 -4.74 -1.01 1428.02 1.00 691 61 295 2 TRUE 2.31
melanoma NRAS_Q61K FLT1 26 28 Female -0.73 -2.45 0.75 1148.75 1.00 323 24 26 2 FALSE 0.41
melanoma NRAS_Q61K FLT1 37 94 Male -1.56 -3.43 -0.26 1250.12 1.00 474 36 93 1 FALSE 1.22
melanoma NRAS_Q61K FLT1 63 122 Sex:overall -1.14 -3.06 0.57 1235.49 1.00 797 60 119 3 FALSE 0.66
melanoma NRAS_Q61K RPTOR 26 15 Female 0.00 -1.60 1.23 922.83 1.00 332 25 14 1 FALSE 0.00
melanoma NRAS_Q61K RPTOR 37 36 Male 0.09 -1.21 1.15 663.42 1.00 512 34 33 3 FALSE 0.05
melanoma NRAS_Q61K RPTOR 63 51 Sex:overall 0.04 -1.54 1.38 696.44 1.01 844 59 47 4 FALSE 0.02
melanoma NRAS_Q61K SF3B1 26 44 Female -2.68 -5.73 -0.59 1408.70 1.00 302 26 44 0 TRUE 1.32
melanoma NRAS_Q61K SF3B1 37 48 Male -2.35 -5.22 -0.48 1256.57 1.00 496 36 47 1 TRUE 1.24
melanoma NRAS_Q61K SF3B1 63 92 Sex:overall -2.48 -5.47 -0.34 1387.67 1.00 798 62 91 1 TRUE 1.20
melanoma NRAS_Q61K ROS1 26 68 Female -0.61 -1.83 0.45 1204.38 1.00 307 22 64 4 TRUE 0.53
melanoma NRAS_Q61K ROS1 37 186 Male -1.36 -2.57 -0.40 1492.47 1.00 423 34 183 3 TRUE 1.87
melanoma NRAS_Q61K ROS1 63 254 Sex:overall -0.99 -2.57 0.44 1505.68 1.00 730 56 247 7 TRUE 0.71
melanoma NRAS_Q61K FLT3 27 27 Female 0.05 -0.98 1.01 682.57 1.00 330 25 25 2 TRUE 0.04
melanoma NRAS_Q61K FLT3 38 53 Male 0.10 -0.85 0.96 721.09 1.00 507 34 49 4 TRUE 0.08
melanoma NRAS_Q61K FLT3 65 80 Sex:overall 0.08 -0.99 1.12 855.57 1.00 837 59 74 6 TRUE 0.05
melanoma NRAS_Q61K AXL 26 15 Female 0.10 -1.55 1.28 1511.07 1.00 334 25 14 1 FALSE 0.05
melanoma NRAS_Q61K AXL 38 48 Male 0.41 -0.58 1.33 492.95 1.01 505 33 43 5 FALSE 0.39
melanoma NRAS_Q61K AXL 64 63 Sex:overall 0.25 -1.26 1.55 1275.87 1.00 839 58 57 6 FALSE 0.14
melanoma NRAS_Q61K PIK3CG 26 27 Female -1.45 -3.53 0.17 1463.81 1.00 324 25 26 1 FALSE 0.94
melanoma NRAS_Q61K PIK3CG 37 79 Male -1.73 -3.67 -0.27 1411.11 1.00 488 36 78 1 FALSE 1.33
melanoma NRAS_Q61K PIK3CG 63 106 Sex:overall -1.56 -3.63 0.20 1415.82 1.00 812 61 104 2 FALSE 0.92
melanoma NRAS_Q61K EGFR 27 20 Female -0.34 -1.80 0.83 1120.52 1.00 334 26 19 1 TRUE 0.21
melanoma NRAS_Q61K EGFR 38 47 Male -0.23 -1.47 0.76 1461.47 1.00 515 35 44 3 TRUE 0.16
melanoma NRAS_Q61K EGFR 65 67 Sex:overall -0.29 -1.67 0.93 1347.14 1.00 849 61 63 4 TRUE 0.17
melanoma NRAS_Q61K ARID1B 26 19 Female -2.45 -5.91 -0.31 1397.25 1.00 329 26 19 0 TRUE 1.03
melanoma NRAS_Q61K ARID1B 37 56 Male -2.16 -4.90 -0.29 1274.26 1.00 503 36 55 1 TRUE 1.14
melanoma NRAS_Q61K ARID1B 63 75 Sex:overall -2.26 -5.01 -0.08 1385.60 1.00 832 62 74 1 TRUE 1.07
melanoma NRAS_Q61K GNA11 27 20 Female -5.35 -12.21 -1.02 367.08 1.00 333 27 20 0 TRUE 1.17
melanoma NRAS_Q61K GNA11 38 34 Male -5.38 -12.29 -1.07 366.96 1.00 518 38 34 0 TRUE 1.17
melanoma NRAS_Q61K GNA11 65 54 Sex:overall -5.30 -12.04 -1.07 367.14 1.00 851 65 54 0 TRUE 1.18
melanoma NRAS_Q61K INSR 25 21 Female -0.47 -2.05 0.89 1224.14 1.00 316 23 19 2 FALSE 0.28
melanoma NRAS_Q61K INSR 35 46 Male -0.73 -2.30 0.44 1329.70 1.00 480 34 45 1 FALSE 0.50
melanoma NRAS_Q61K INSR 60 67 Sex:overall -0.60 -2.25 0.74 1355.96 1.00 796 57 64 3 FALSE 0.36
melanoma NRAS_Q61K ERG 26 11 Female -0.99 -4.33 0.89 1289.56 1.00 337 26 11 0 FALSE 0.33
melanoma NRAS_Q61K ERG 37 42 Male -0.24 -1.69 0.93 1443.83 1.00 510 34 39 3 FALSE 0.14
melanoma NRAS_Q61K ERG 63 53 Sex:overall -0.56 -3.04 1.21 1436.55 1.00 847 60 50 3 FALSE 0.21
melanoma NRAS_Q61K MET 27 24 Female -0.37 -1.90 0.81 1327.28 1.00 332 26 23 1 TRUE 0.24
melanoma NRAS_Q61K MET 38 61 Male -0.18 -1.28 0.80 1330.10 1.00 501 34 57 4 TRUE 0.13
melanoma NRAS_Q61K MET 65 85 Sex:overall -0.27 -1.58 0.94 1381.30 1.00 833 60 80 5 TRUE 0.17
melanoma NRAS_Q61K BRAF 27 99 Female -2.51 -6.54 -0.75 1152.29 1.00 257 27 99 0 TRUE 0.98
melanoma NRAS_Q61K BRAF 41 200 Male -0.87 -1.80 -0.05 510.07 1.00 375 32 191 9 TRUE 1.34
melanoma NRAS_Q61K BRAF 68 299 Sex:overall -1.62 -4.61 0.09 1295.26 1.00 632 59 290 9 TRUE 0.83
melanoma NRAS_Q61K TET2 26 23 Female -0.91 -2.59 0.51 1374.78 1.00 326 25 22 1 TRUE 0.61
melanoma NRAS_Q61K TET2 37 69 Male -0.96 -2.37 0.14 1421.25 1.00 489 35 67 2 TRUE 0.84
melanoma NRAS_Q61K TET2 63 92 Sex:overall -0.92 -2.60 0.56 1040.33 1.00 815 60 89 3 TRUE 0.59
melanoma NRAS_Q61K PDGFRB 37 57 Male -6.00 -15.49 -1.17 1241.73 1.00 502 37 57 0 TRUE 0.84
melanoma NRAS_Q61K PDGFRB 37 57 Sex:overall -4.48 -11.90 2.38 1191.88 1.00 502 37 57 0 TRUE 0.68
melanoma NRAS_Q61K CARD11 26 28 Female -0.54 -2.05 0.63 1294.84 1.00 325 25 27 1 FALSE 0.34
melanoma NRAS_Q61K CARD11 38 84 Male -0.28 -1.32 0.60 1283.85 1.00 479 33 79 5 FALSE 0.24
melanoma NRAS_Q61K CARD11 64 112 Sex:overall -0.39 -1.82 0.92 1313.32 1.00 804 58 106 6 FALSE 0.22
melanoma NRAS_Q61K CBL 26 27 Female -0.84 -2.44 0.41 1115.88 1.00 322 25 26 1 TRUE 0.65
melanoma NRAS_Q61K CBL 37 56 Male -0.84 -2.35 0.32 1134.33 1.00 495 35 54 2 TRUE 0.71
melanoma NRAS_Q61K CBL 63 83 Sex:overall -0.82 -2.34 0.52 1081.87 1.00 817 60 80 3 TRUE 0.61
melanoma NRAS_Q61K TP63 25 45 Female 0.18 -0.74 1.07 1557.77 1.00 302 21 41 4 FALSE 0.15
melanoma NRAS_Q61K TP63 37 126 Male 0.14 -0.62 0.82 1450.42 1.00 422 28 117 9 FALSE 0.15
melanoma NRAS_Q61K TP63 62 171 Sex:overall 0.17 -1.08 1.38 1463.82 1.00 724 49 158 13 FALSE 0.11
melanoma NRAS_Q61K GLI1 26 14 Female -0.47 -2.30 1.02 1233.15 1.00 313 25 13 1 FALSE 0.24
melanoma NRAS_Q61K GLI1 34 48 Male -0.56 -2.04 0.59 1225.01 1.00 477 32 46 2 FALSE 0.38
melanoma NRAS_Q61K GLI1 60 62 Sex:overall -0.51 -2.34 1.00 1135.67 1.00 790 57 59 3 FALSE 0.25
melanoma NRAS_Q61K ZFHX3 26 29 Female -2.49 -6.30 -0.46 1408.66 1.00 299 26 29 0 FALSE 1.09
melanoma NRAS_Q61K ZFHX3 34 116 Male -1.86 -3.69 -0.50 1550.04 1.00 455 32 114 2 FALSE 1.65
melanoma NRAS_Q61K ZFHX3 60 145 Sex:overall -2.13 -4.82 -0.06 1530.70 1.00 754 58 143 2 FALSE 1.15
melanoma NRAS_Q61K MGA 26 23 Female 0.16 -1.16 1.24 1340.81 1.00 305 24 21 2 FALSE 0.10
melanoma NRAS_Q61K MGA 34 73 Male 0.30 -0.65 1.13 1381.98 1.00 464 28 67 6 FALSE 0.30
melanoma NRAS_Q61K MGA 60 96 Sex:overall 0.22 -1.21 1.53 1464.27 1.00 769 52 88 8 FALSE 0.12
melanoma NRAS_Q61K ANKRD11 25 21 Female -0.70 -2.65 0.99 965.34 1.00 297 23 19 2 FALSE 0.36
melanoma NRAS_Q61K ANKRD11 32 55 Male -1.99 -6.44 -0.14 986.09 1.00 442 32 55 0 FALSE 0.63
melanoma NRAS_Q61K ANKRD11 57 76 Sex:overall -1.28 -4.15 0.76 1425.69 1.00 739 55 74 2 FALSE 0.50
melanoma NRAS_Q61K PGR 25 14 Female -0.76 -2.75 0.91 1309.80 1.00 301 24 13 1 FALSE 0.38
melanoma NRAS_Q61K PGR 32 42 Male -1.02 -2.98 0.42 1197.29 1.00 447 31 41 1 FALSE 0.63
melanoma NRAS_Q61K PGR 57 56 Sex:overall -0.90 -2.79 0.80 1222.17 1.00 748 55 54 2 FALSE 0.47
melanoma NRAS_Q61K PLCG2 25 20 Female -2.22 -5.38 -0.11 1125.66 1.00 296 25 20 0 FALSE 0.92
melanoma NRAS_Q61K PLCG2 32 43 Male -1.97 -4.65 -0.15 1314.24 1.00 446 31 42 1 FALSE 1.04
melanoma NRAS_Q61K PLCG2 57 63 Sex:overall -2.06 -4.96 -0.04 1197.35 1.00 742 56 62 1 FALSE 0.99
melanoma NRAS_Q61K EPHA7 26 28 Female 1.10 0.02 2.17 1498.03 1.00 305 20 22 6 FALSE 1.38
melanoma NRAS_Q61K EPHA7 35 131 Male -0.46 -1.51 0.43 1535.17 1.00 426 30 126 5 FALSE 0.45
melanoma NRAS_Q61K EPHA7 61 159 Sex:overall 0.29 -1.81 2.43 1457.45 1.00 731 50 148 11 FALSE 0.10
melanoma NRAS_Q61R SPEN 36 26 Female 0.09 -1.20 1.31 1409.96 1.00 318 32 22 4 FALSE 0.05
melanoma NRAS_Q61R SPEN 45 91 Male -1.07 -2.50 -0.02 1290.82 1.00 475 43 89 2 FALSE 1.03
melanoma NRAS_Q61R SPEN 81 117 Sex:overall -0.48 -2.29 1.23 1334.51 1.00 793 75 111 6 FALSE 0.24
melanoma NRAS_Q61R KMT2C 36 33 Female 0.20 -0.85 1.22 1422.36 1.00 300 31 28 5 FALSE 0.15
melanoma NRAS_Q61R KMT2C 43 116 Male -0.58 -1.55 0.23 1640.57 1.00 421 38 111 5 FALSE 0.69
melanoma NRAS_Q61R KMT2C 79 149 Sex:overall -0.18 -1.79 1.51 1528.46 1.00 721 69 139 10 FALSE 0.08
melanoma NRAS_Q61R TP53 37 63 Female -0.42 -1.27 0.37 1412.82 1.00 287 32 58 5 TRUE 0.50
melanoma NRAS_Q61R TP53 45 147 Male -0.55 -1.34 0.13 1389.29 1.00 430 38 140 7 TRUE 0.85
thyroid cancer NRAS_Q61R TP53 32 28 Female 0.44 -0.46 1.35 1384.09 1.00 168 25 21 7 TRUE 0.48
thyroid cancer NRAS_Q61R TP53 33 49 Male 0.03 -0.95 0.87 1270.22 1.00 195 28 44 5 TRUE 0.02
melanoma NRAS_Q61R TP53 82 210 Sex:overall -0.48 -1.46 0.54 1451.08 1.00 717 70 198 12 TRUE 0.46
thyroid cancer NRAS_Q61R TP53 65 77 Sex:overall 0.23 -0.97 1.34 1535.16 1.00 363 53 65 12 TRUE 0.15
melanoma NRAS_Q61R ATRX 37 71 Female -0.38 -1.43 0.54 1417.76 1.00 291 31 65 6 TRUE 0.35
melanoma NRAS_Q61R ATRX 45 37 Male -2.21 -6.41 -0.12 1096.54 1.00 505 45 37 0 TRUE 0.68
melanoma NRAS_Q61R ATRX 82 108 Sex:overall -1.23 -4.26 0.75 1354.30 1.00 796 76 102 6 TRUE 0.47
melanoma NRAS_Q61R ATR 36 16 Female -0.40 -1.99 0.80 1200.61 1.00 323 35 15 1 FALSE 0.24
melanoma NRAS_Q61R ATR 46 49 Male -0.15 -1.28 0.78 1251.65 1.00 492 42 45 4 FALSE 0.11
melanoma NRAS_Q61R ATR 82 65 Sex:overall -0.30 -1.91 1.04 1218.56 1.00 815 77 60 5 FALSE 0.17
melanoma NRAS_Q61R PDGFRA 37 24 Female -2.25 -5.02 -0.27 844.06 1.00 323 36 23 1 TRUE 1.20
melanoma NRAS_Q61R PDGFRA 45 54 Male -2.65 -5.65 -0.74 912.80 1.00 501 45 54 0 TRUE 1.36
melanoma NRAS_Q61R PDGFRA 82 78 Sex:overall -2.40 -5.32 -0.32 921.63 1.00 824 81 77 1 TRUE 1.21
melanoma NRAS_Q61R NSD1 36 15 Female -0.45 -2.08 0.81 1315.96 1.00 322 35 14 1 FALSE 0.27
melanoma NRAS_Q61R NSD1 45 42 Male -0.32 -1.62 0.72 1301.67 1.00 500 42 39 3 FALSE 0.22
melanoma NRAS_Q61R NSD1 81 57 Sex:overall -0.39 -2.10 0.97 1301.70 1.00 822 77 53 4 FALSE 0.21
melanoma NRAS_Q61R FLT4 36 24 Female 0.15 -0.91 1.11 1374.65 1.00 317 33 21 3 TRUE 0.11
melanoma NRAS_Q61R FLT4 45 69 Male 0.12 -0.73 0.90 1291.10 1.00 484 39 63 6 TRUE 0.11
melanoma NRAS_Q61R FLT4 81 93 Sex:overall 0.12 -1.12 1.24 1285.48 1.00 801 72 84 9 TRUE 0.08
melanoma NRAS_Q61R PTPRD 37 54 Female -0.10 -1.03 0.73 1589.07 1.00 299 32 49 5 FALSE 0.08
melanoma NRAS_Q61R PTPRD 52 219 Male 0.04 -0.51 0.60 1404.40 1.00 414 34 201 18 FALSE 0.05
melanoma NRAS_Q61R PTPRD 89 273 Sex:overall -0.02 -1.43 1.46 1492.33 1.00 713 66 250 23 FALSE 0.01
melanoma NRAS_Q61R RET 37 14 Female -1.78 -5.30 0.10 1338.21 1.00 329 37 14 0 TRUE 0.70
melanoma NRAS_Q61R RET 45 50 Male -1.14 -2.87 0.23 1347.33 1.00 506 43 48 2 TRUE 0.82
melanoma NRAS_Q61R RET 82 64 Sex:overall -1.39 -3.85 0.58 1330.34 1.00 835 80 62 2 TRUE 0.65
melanoma NRAS_Q61R PIK3C2G 37 39 Female 0.39 -0.52 1.30 1407.45 1.00 297 31 33 6 FALSE 0.41
melanoma NRAS_Q61R PIK3C2G 43 157 Male 0.11 -0.62 0.77 1409.72 1.00 412 31 145 12 FALSE 0.13
melanoma NRAS_Q61R PIK3C2G 80 196 Sex:overall 0.27 -1.13 1.87 1525.85 1.00 709 62 178 18 FALSE 0.14
melanoma NRAS_Q61R CREBBP 36 15 Female -0.11 -1.49 1.23 1373.85 1.00 323 34 13 2 TRUE 0.06
melanoma NRAS_Q61R CREBBP 45 57 Male -0.41 -1.58 0.59 1449.84 1.00 491 42 54 3 TRUE 0.34
melanoma NRAS_Q61R CREBBP 81 72 Sex:overall -0.25 -1.93 1.37 1504.69 1.00 814 76 67 5 TRUE 0.12
melanoma NRAS_Q61R DOT1L 36 14 Female 0.04 -1.39 1.26 1528.55 1.00 326 34 12 2 FALSE 0.02
melanoma NRAS_Q61R DOT1L 45 43 Male -0.10 -1.28 0.86 1429.16 1.00 499 42 40 3 FALSE 0.07
melanoma NRAS_Q61R DOT1L 81 57 Sex:overall -0.04 -1.60 1.43 1537.92 1.00 825 76 52 5 FALSE 0.02
melanoma NRAS_Q61R PTPRS 36 29 Female -0.09 -1.21 0.98 1401.79 1.00 300 32 25 4 FALSE 0.06
melanoma NRAS_Q61R PTPRS 42 38 Male -0.50 -1.91 0.58 1199.19 1.00 472 41 37 1 FALSE 0.36
melanoma NRAS_Q61R PTPRS 78 67 Sex:overall -0.29 -1.66 0.97 1250.74 1.00 772 73 62 5 FALSE 0.17
melanoma NRAS_Q61R SMARCA4 36 24 Female 0.49 -0.42 1.45 1041.25 1.00 318 31 19 5 FALSE 0.49
melanoma NRAS_Q61R SMARCA4 45 48 Male 0.10 -1.03 0.98 1443.06 1.00 495 42 45 3 FALSE 0.07
melanoma NRAS_Q61R SMARCA4 81 72 Sex:overall 0.30 -0.86 1.45 1533.74 1.00 813 73 64 8 FALSE 0.21
melanoma NRAS_Q61R PTPRT 38 101 Female -0.07 -0.78 0.58 1390.37 1.00 276 29 92 9 FALSE 0.08
melanoma NRAS_Q61R PTPRT 50 271 Male 0.01 -0.55 0.57 1473.96 1.00 394 30 251 20 FALSE 0.02
melanoma NRAS_Q61R PTPRT 88 372 Sex:overall -0.03 -1.28 1.21 1596.79 1.00 670 59 343 29 FALSE 0.02
melanoma NRAS_Q61R HGF 36 16 Female -1.67 -5.50 0.28 1153.32 1.00 321 36 16 0 FALSE 0.52
melanoma NRAS_Q61R HGF 45 67 Male -0.58 -1.79 0.46 1322.69 1.00 483 41 63 4 FALSE 0.51
melanoma NRAS_Q61R HGF 81 83 Sex:overall -1.07 -3.58 0.68 1219.71 1.00 804 77 79 4 FALSE 0.49
melanoma NRAS_Q61R ALK 37 43 Female 0.23 -0.63 1.03 1486.26 1.00 314 31 37 6 TRUE 0.23
melanoma NRAS_Q61R ALK 45 85 Male 0.07 -0.72 0.76 1339.37 1.00 483 39 79 6 TRUE 0.07
melanoma NRAS_Q61R ALK 82 128 Sex:overall 0.13 -0.85 1.04 1337.97 1.00 797 70 116 12 TRUE 0.10
melanoma NRAS_Q61R BAP1 36 27 Female -2.42 -5.28 -0.44 658.42 1.01 309 36 27 0 TRUE 1.22
melanoma NRAS_Q61R BAP1 45 39 Male -2.23 -4.74 -0.38 353.71 1.01 499 44 38 1 TRUE 1.22
melanoma NRAS_Q61R BAP1 81 66 Sex:overall -2.29 -5.01 -0.27 372.26 1.01 808 80 65 1 TRUE 1.18
melanoma NRAS_Q61R PTEN 37 29 Female 0.08 -0.87 1.02 1395.97 1.00 318 33 25 4 TRUE 0.06
melanoma NRAS_Q61R PTEN 45 50 Male -0.09 -1.12 0.76 1235.05 1.00 498 42 47 3 TRUE 0.07
melanoma NRAS_Q61R PTEN 82 79 Sex:overall 0.00 -0.99 1.00 1407.66 1.00 816 75 72 7 TRUE 0.00
melanoma NRAS_Q61R CTNNB1 37 21 Female -0.21 -1.80 0.80 134.62 1.03 324 36 20 1 TRUE 0.12
melanoma NRAS_Q61R CTNNB1 45 37 Male 0.04 -1.15 1.03 282.69 1.02 512 41 33 4 TRUE 0.03
melanoma NRAS_Q61R CTNNB1 82 58 Sex:overall -0.08 -1.50 0.94 228.05 1.02 836 77 53 5 TRUE 0.05
melanoma NRAS_Q61R ARID1A 36 28 Female -0.40 -1.52 0.65 1490.09 1.00 313 33 25 3 TRUE 0.31
melanoma NRAS_Q61R ARID1A 45 61 Male -0.69 -1.94 0.31 1413.95 1.00 485 43 59 2 TRUE 0.65
melanoma NRAS_Q61R ARID1A 81 89 Sex:overall -0.53 -1.93 0.78 1403.53 1.00 798 76 84 5 TRUE 0.37
melanoma NRAS_Q61R IKZF1 36 32 Female -1.81 -3.77 -0.24 1417.80 1.00 309 35 31 1 TRUE 1.38
melanoma NRAS_Q61R IKZF1 45 77 Male -1.97 -4.04 -0.50 1335.50 1.00 482 44 76 1 TRUE 1.53
melanoma NRAS_Q61R IKZF1 81 109 Sex:overall -1.87 -3.90 -0.20 1357.87 1.00 791 79 107 2 TRUE 1.30
melanoma NRAS_Q61R TERT 40 188 Female 1.16 0.49 1.82 1619.88 1.00 202 12 160 28 TRUE 3.19
melanoma NRAS_Q61R TERT 50 426 Male 1.22 0.56 1.88 1517.11 1.00 229 7 383 43 TRUE 3.32
thyroid cancer NRAS_Q61R TERT 29 121 Female 0.52 -0.09 1.16 727.45 1.00 79 10 102 19 TRUE 0.92
thyroid cancer NRAS_Q61R TERT 29 135 Male 0.55 -0.03 1.25 543.02 1.00 102 9 115 20 TRUE 1.00
melanoma NRAS_Q61R TERT 90 614 Sex:overall 1.15 -0.19 2.39 1445.60 1.00 431 19 543 71 TRUE 1.14
thyroid cancer NRAS_Q61R TERT 58 256 Sex:overall 0.53 -0.14 1.37 919.75 1.00 181 19 217 39 TRUE 0.78
melanoma NRAS_Q61R FAT1 38 46 Female 0.41 -0.43 1.26 1073.40 1.00 303 30 38 8 FALSE 0.47
melanoma NRAS_Q61R FAT1 45 103 Male -0.27 -1.21 0.49 1061.29 1.00 462 40 98 5 FALSE 0.26
melanoma NRAS_Q61R FAT1 83 149 Sex:overall 0.08 -1.32 1.30 1402.68 1.00 765 70 136 13 FALSE 0.04
melanoma NRAS_Q61R CIC 36 19 Female -1.91 -4.53 -0.03 796.68 1.00 319 35 18 1 TRUE 1.06
melanoma NRAS_Q61R CIC 45 35 Male -2.23 -5.17 -0.32 925.76 1.00 503 45 35 0 TRUE 1.13
melanoma NRAS_Q61R CIC 81 54 Sex:overall -2.05 -4.73 -0.10 901.72 1.00 822 80 53 1 TRUE 1.10
melanoma NRAS_Q61R KDM6A 45 61 Male -2.13 -4.94 -0.25 1136.81 1.00 518 44 60 1 FALSE 1.12
melanoma NRAS_Q61R KDM6A 45 61 Sex:overall -1.88 -6.65 2.84 1373.35 1.00 518 44 60 1 FALSE 0.40
melanoma NRAS_Q61R POLE 36 22 Female 0.15 -0.90 1.11 1316.69 1.00 317 33 19 3 TRUE 0.11
melanoma NRAS_Q61R POLE 45 50 Male 0.06 -0.87 0.91 1399.72 1.00 494 41 46 4 TRUE 0.05
melanoma NRAS_Q61R POLE 81 72 Sex:overall 0.10 -1.08 1.12 1336.91 1.00 811 74 65 7 TRUE 0.07
melanoma NRAS_Q61R NOTCH2 36 11 Female -2.68 -6.84 -0.17 1367.52 1.00 312 36 11 0 TRUE 0.90
melanoma NRAS_Q61R NOTCH2 42 54 Male -2.24 -4.98 -0.32 1401.37 1.00 460 41 53 1 TRUE 1.24
melanoma NRAS_Q61R NOTCH2 78 65 Sex:overall -2.37 -5.65 0.13 1351.47 1.00 772 77 64 1 TRUE 0.98
melanoma NRAS_Q61R KMT2A 37 45 Female 0.21 -0.54 0.97 1084.59 1.00 306 31 39 6 FALSE 0.23
melanoma NRAS_Q61R KMT2A 45 95 Male 0.08 -0.64 0.74 869.91 1.00 476 38 88 7 FALSE 0.08
melanoma NRAS_Q61R KMT2A 82 140 Sex:overall 0.14 -0.75 1.02 1174.53 1.00 782 69 127 13 FALSE 0.11
melanoma NRAS_Q61R PAK7 36 57 Female -0.03 -0.92 0.79 1516.65 1.00 277 30 51 6 FALSE 0.03
melanoma NRAS_Q61R PAK7 44 161 Male -0.13 -0.80 0.50 1622.37 1.00 405 33 150 11 FALSE 0.15
melanoma NRAS_Q61R PAK7 80 218 Sex:overall -0.07 -1.07 1.10 1596.67 1.00 682 63 201 17 FALSE 0.05
melanoma NRAS_Q61R BRCA2 37 23 Female 0.60 -0.66 1.75 1534.39 1.00 322 32 18 5 TRUE 0.48
melanoma NRAS_Q61R BRCA2 45 69 Male -1.32 -3.38 0.07 1272.70 1.00 482 44 68 1 TRUE 0.86
melanoma NRAS_Q61R BRCA2 82 92 Sex:overall -0.31 -2.54 1.94 1590.01 1.00 804 76 86 6 TRUE 0.11
melanoma NRAS_Q61R NOTCH3 36 27 Female -1.30 -3.08 0.09 1459.17 1.00 314 35 26 1 TRUE 0.95
melanoma NRAS_Q61R NOTCH3 45 103 Male -1.25 -2.46 -0.24 1471.61 1.00 461 42 100 3 TRUE 1.53
melanoma NRAS_Q61R NOTCH3 81 130 Sex:overall -1.25 -3.18 0.55 1250.80 1.00 775 77 126 4 TRUE 0.77
melanoma NRAS_Q61R NOTCH4 36 32 Female 0.04 -0.98 1.09 1537.70 1.00 301 32 28 4 TRUE 0.03
melanoma NRAS_Q61R NOTCH4 43 116 Male -0.24 -1.06 0.47 1499.11 1.00 425 36 109 7 TRUE 0.27
melanoma NRAS_Q61R NOTCH4 79 148 Sex:overall -0.08 -1.44 1.30 1449.82 1.00 726 68 137 11 TRUE 0.04
melanoma NRAS_Q61R CDKN2A 37 39 Female -0.45 -1.58 0.65 1221.35 1.00 312 33 35 4 TRUE 0.36
melanoma NRAS_Q61R CDKN2A 45 90 Male -1.03 -2.39 -0.05 1497.76 1.00 466 43 88 2 TRUE 1.13
melanoma NRAS_Q61R CDKN2A 82 129 Sex:overall -0.72 -2.05 0.67 1479.71 1.00 778 76 123 6 TRUE 0.55
melanoma NRAS_Q61R EPHB1 36 13 Female -1.26 -5.77 0.74 1476.15 1.00 325 36 13 0 FALSE 0.33
melanoma NRAS_Q61R EPHB1 45 53 Male 0.23 -0.75 1.12 1519.77 1.00 492 39 47 6 FALSE 0.20
melanoma NRAS_Q61R EPHB1 81 66 Sex:overall -0.44 -3.15 1.70 1476.75 1.00 817 75 60 6 FALSE 0.15
melanoma NRAS_Q61R IL7R 36 28 Female -0.29 -1.43 0.74 1305.53 1.00 316 33 25 3 FALSE 0.22
melanoma NRAS_Q61R IL7R 45 66 Male -0.46 -1.60 0.44 1142.59 1.00 485 42 63 3 FALSE 0.43
melanoma NRAS_Q61R IL7R 81 94 Sex:overall -0.38 -1.64 0.78 1175.31 1.00 801 75 88 6 FALSE 0.26
melanoma NRAS_Q61R ATM 37 20 Female -1.30 -5.67 0.49 1232.58 1.00 324 37 20 0 TRUE 0.37
melanoma NRAS_Q61R ATM 46 58 Male 0.29 -0.61 1.17 1355.13 1.00 497 39 51 7 TRUE 0.28
melanoma NRAS_Q61R ATM 83 78 Sex:overall -0.46 -3.43 1.30 1416.32 1.00 821 76 71 7 TRUE 0.16
melanoma NRAS_Q61R MAP2K1 36 14 Female -1.65 -4.51 0.16 988.69 1.00 323 36 14 0 TRUE 0.76
melanoma NRAS_Q61R MAP2K1 45 44 Male -1.18 -2.77 0.19 596.53 1.00 494 43 42 2 TRUE 0.90
melanoma NRAS_Q61R MAP2K1 81 58 Sex:overall -1.39 -3.62 0.37 933.50 1.00 817 79 56 2 TRUE 0.75
melanoma NRAS_Q61R RB1 38 18 Female 0.90 -0.03 1.80 1202.20 1.00 331 34 14 4 TRUE 1.31
melanoma NRAS_Q61R RB1 45 33 Male 0.86 0.05 1.65 1213.90 1.00 520 40 28 5 TRUE 1.39
melanoma NRAS_Q61R RB1 83 51 Sex:overall 0.87 -0.15 1.76 1289.29 1.00 851 74 42 9 TRUE 1.05
melanoma NRAS_Q61R KMT2D 36 57 Female 0.00 -0.84 0.77 1420.28 1.00 299 30 51 6 FALSE 0.00
melanoma NRAS_Q61R KMT2D 50 161 Male -0.16 -0.83 0.47 1337.57 1.00 443 39 150 11 FALSE 0.21
melanoma NRAS_Q61R KMT2D 86 218 Sex:overall -0.08 -1.16 1.04 1500.30 1.00 742 69 201 17 FALSE 0.06
melanoma NRAS_Q61R APC 37 33 Female -1.14 -2.77 0.07 1476.50 1.00 318 36 32 1 TRUE 0.97
melanoma NRAS_Q61R APC 46 93 Male -0.89 -1.93 -0.01 1292.95 1.00 480 42 89 4 TRUE 1.13
melanoma NRAS_Q61R APC 83 126 Sex:overall -0.98 -2.49 0.50 1433.90 1.00 798 78 121 5 TRUE 0.73
melanoma NRAS_Q61R ARID2 39 45 Female 0.17 -0.70 1.05 1337.05 1.00 302 32 38 7 FALSE 0.15
melanoma NRAS_Q61R ARID2 47 105 Male -0.37 -1.23 0.40 1392.46 1.00 477 42 100 5 FALSE 0.42
melanoma NRAS_Q61R ARID2 86 150 Sex:overall -0.10 -1.29 1.10 1617.16 1.00 779 74 138 12 FALSE 0.06
melanoma NRAS_Q61R MTOR 45 43 Male -0.72 -2.62 0.57 259.25 1.01 499 43 41 2 TRUE 0.42
melanoma NRAS_Q61R MTOR 45 43 Sex:overall -0.55 -4.85 4.05 1210.29 1.00 499 43 41 2 TRUE 0.10
melanoma NRAS_Q61R NOTCH1 37 13 Female -1.12 -3.19 0.71 1320.49 1.00 333 36 12 1 TRUE 0.56
melanoma NRAS_Q61R NOTCH1 45 54 Male -1.53 -3.70 -0.08 1366.19 1.00 500 44 53 1 TRUE 1.03
melanoma NRAS_Q61R NOTCH1 82 67 Sex:overall -1.30 -3.65 0.81 1504.04 1.00 833 80 65 2 TRUE 0.63
melanoma NRAS_Q61R NTRK1 45 42 Male -0.75 -2.53 0.66 948.24 1.00 500 43 40 2 TRUE 0.45
melanoma NRAS_Q61R NTRK1 45 42 Sex:overall -0.66 -4.88 3.94 1381.12 1.00 500 43 40 2 TRUE 0.13
melanoma NRAS_Q61R SETD2 36 20 Female -0.13 -1.52 0.96 1448.03 1.00 323 34 18 2 FALSE 0.08
melanoma NRAS_Q61R SETD2 45 69 Male -0.13 -1.10 0.68 1590.65 1.00 483 40 64 5 FALSE 0.11
melanoma NRAS_Q61R SETD2 81 89 Sex:overall -0.10 -1.60 1.30 1549.99 1.00 806 74 82 7 FALSE 0.05
melanoma NRAS_Q61R PBRM1 36 15 Female -0.20 -1.77 1.31 1429.67 1.00 325 34 13 2 TRUE 0.10
melanoma NRAS_Q61R PBRM1 45 59 Male -0.81 -2.16 0.32 1462.98 1.00 489 43 57 2 TRUE 0.68
melanoma NRAS_Q61R PBRM1 81 74 Sex:overall -0.51 -2.47 1.52 1512.00 1.00 814 77 70 4 TRUE 0.23
melanoma NRAS_Q61R EPHA3 36 20 Female -0.04 -1.42 1.10 1541.20 1.00 320 34 18 2 FALSE 0.02
melanoma NRAS_Q61R EPHA3 46 87 Male 0.15 -0.67 0.92 1409.16 1.00 477 38 79 8 FALSE 0.15
melanoma NRAS_Q61R EPHA3 82 107 Sex:overall 0.03 -1.71 1.62 1462.47 1.00 797 72 97 10 FALSE 0.01
melanoma NRAS_Q61R KIT 37 31 Female -2.46 -5.44 -0.46 210.76 1.02 314 37 31 0 TRUE 1.22
melanoma NRAS_Q61R KIT 45 34 Male -2.13 -4.57 -0.27 92.47 1.03 515 44 33 1 TRUE 1.13
melanoma NRAS_Q61R KIT 82 65 Sex:overall -2.25 -4.83 -0.20 116.55 1.03 829 81 64 1 TRUE 1.14
melanoma NRAS_Q61R KDR 37 40 Female 0.16 -0.63 0.90 141.86 1.02 315 32 35 5 TRUE 0.17
melanoma NRAS_Q61R KDR 46 92 Male 0.07 -0.68 0.75 294.06 1.01 479 39 85 7 TRUE 0.08
melanoma NRAS_Q61R KDR 83 132 Sex:overall 0.12 -0.90 0.97 386.21 1.02 794 71 120 12 TRUE 0.10
melanoma NRAS_Q61R CSF1R 45 48 Male -1.88 -4.74 -0.11 1130.65 1.00 505 44 47 1 TRUE 0.98
melanoma NRAS_Q61R CSF1R 45 48 Sex:overall -1.67 -6.08 2.60 1207.99 1.00 505 44 47 1 TRUE 0.36
melanoma NRAS_Q61R PTCH1 45 46 Male -0.91 -2.65 0.40 1388.97 1.00 495 43 44 2 TRUE 0.63
melanoma NRAS_Q61R PTCH1 45 46 Sex:overall -0.69 -4.66 4.21 1434.69 1.00 495 43 44 2 TRUE 0.13
melanoma NRAS_Q61R TET1 36 11 Female -0.36 -1.92 1.13 1209.46 1.00 314 35 10 1 FALSE 0.19
melanoma NRAS_Q61R TET1 42 44 Male -0.30 -1.53 0.82 518.67 1.01 472 39 41 3 FALSE 0.21
melanoma NRAS_Q61R TET1 78 55 Sex:overall -0.34 -2.10 1.30 1167.16 1.00 786 74 51 4 FALSE 0.15
melanoma NRAS_Q61R FGFR2 37 19 Female -0.31 -1.66 0.94 1316.85 1.00 327 35 17 2 TRUE 0.19
melanoma NRAS_Q61R FGFR2 45 66 Male -0.56 -1.75 0.42 1386.44 1.00 498 42 63 3 TRUE 0.52
melanoma NRAS_Q61R FGFR2 82 85 Sex:overall -0.42 -2.01 1.02 1553.09 1.00 825 77 80 5 TRUE 0.22
melanoma NRAS_Q61R TBX3 45 51 Male -1.86 -4.48 0.04 291.48 1.01 495 44 50 1 FALSE 0.90
melanoma NRAS_Q61R TBX3 45 51 Sex:overall -1.55 -5.77 3.24 1251.44 1.00 495 44 50 1 FALSE 0.32
melanoma NRAS_Q61R DICER1 38 21 Female 2.10 1.08 3.05 1426.18 1.00 326 28 11 10 TRUE 4.53
melanoma NRAS_Q61R DICER1 45 41 Male -0.84 -2.88 0.68 1373.43 1.00 505 44 40 1 TRUE 0.43
melanoma NRAS_Q61R DICER1 83 62 Sex:overall 0.59 -2.39 3.06 1508.49 1.00 831 72 51 11 TRUE 0.18
melanoma NRAS_Q61R NTRK3 37 24 Female 0.20 -0.99 1.32 1493.43 1.00 319 33 20 4 FALSE 0.13
melanoma NRAS_Q61R NTRK3 45 82 Male -0.65 -1.80 0.28 1352.10 1.00 474 42 79 3 FALSE 0.65
melanoma NRAS_Q61R NTRK3 82 106 Sex:overall -0.20 -1.96 1.50 1371.05 1.00 793 75 99 7 FALSE 0.09
melanoma NRAS_Q61R GRIN2A 36 50 Female -0.85 -2.24 0.23 1324.54 1.00 300 34 48 2 FALSE 0.75
melanoma NRAS_Q61R GRIN2A 50 251 Male -0.11 -0.71 0.51 1388.71 1.00 401 32 233 18 FALSE 0.14
melanoma NRAS_Q61R GRIN2A 86 301 Sex:overall -0.46 -2.18 1.17 1194.88 1.01 701 66 281 20 FALSE 0.23
melanoma NRAS_Q61R BRD4 36 17 Female -0.78 -2.54 0.46 1197.94 1.00 321 35 16 1 FALSE 0.52
melanoma NRAS_Q61R BRD4 45 45 Male -0.77 -2.26 0.37 873.62 1.00 500 43 43 2 FALSE 0.61
melanoma NRAS_Q61R BRD4 81 62 Sex:overall -0.77 -2.58 0.61 1210.03 1.00 821 78 59 3 FALSE 0.46
melanoma NRAS_Q61R ASXL1 36 13 Female -2.20 -5.66 0.03 972.77 1.00 323 36 13 0 TRUE 0.88
melanoma NRAS_Q61R ASXL1 45 38 Male -1.89 -4.61 -0.08 971.56 1.00 503 44 37 1 TRUE 0.94
melanoma NRAS_Q61R ASXL1 81 51 Sex:overall -2.02 -4.90 0.04 878.46 1.00 826 80 50 1 TRUE 0.89
melanoma NRAS_Q61R EP300 37 13 Female -0.26 -2.01 1.32 1386.87 1.00 328 35 11 2 TRUE 0.11
melanoma NRAS_Q61R EP300 45 56 Male -1.28 -3.28 0.04 1535.24 1.00 492 44 55 1 TRUE 0.90
melanoma NRAS_Q61R EP300 82 69 Sex:overall -0.73 -2.83 1.33 1425.38 1.00 820 79 66 3 TRUE 0.31
melanoma NRAS_Q61R ERBB4 39 50 Female 0.01 -0.85 0.80 1583.83 1.00 307 33 44 6 TRUE 0.00
melanoma NRAS_Q61R ERBB4 46 143 Male -0.30 -1.01 0.38 1512.09 1.00 453 38 135 8 TRUE 0.38
melanoma NRAS_Q61R ERBB4 85 193 Sex:overall -0.15 -1.37 1.07 1640.72 1.00 760 71 179 14 TRUE 0.09
melanoma NRAS_Q61R MDC1 36 18 Female 0.50 -0.87 1.73 1424.39 1.00 311 32 14 4 FALSE 0.34
melanoma NRAS_Q61R MDC1 42 65 Male -0.76 -2.20 0.39 1430.55 1.00 455 40 63 2 FALSE 0.60
melanoma NRAS_Q61R MDC1 78 83 Sex:overall -0.12 -2.11 1.90 1387.57 1.00 766 72 77 6 FALSE 0.05
melanoma NRAS_Q61R GNAQ 37 25 Female -5.21 -11.99 -1.24 662.41 1.00 318 37 25 0 TRUE 1.21
melanoma NRAS_Q61R GNAQ 45 34 Male -5.21 -11.89 -1.26 678.89 1.00 511 45 34 0 TRUE 1.19
melanoma NRAS_Q61R GNAQ 82 59 Sex:overall -5.16 -12.00 -1.24 866.64 1.00 829 82 59 0 TRUE 1.19
melanoma NRAS_Q61R MED12 39 29 Female 0.64 -0.32 1.60 1526.09 1.00 319 33 23 6 TRUE 0.72
melanoma NRAS_Q61R MED12 45 24 Male -0.10 -1.85 1.12 1264.77 1.00 514 44 23 1 TRUE 0.05
melanoma NRAS_Q61R MED12 84 53 Sex:overall 0.27 -1.48 1.69 1562.29 1.00 833 77 46 7 TRUE 0.13
melanoma NRAS_Q61R NF1 36 79 Female -1.44 -2.64 -0.46 1469.09 1.00 276 34 77 2 TRUE 2.08
melanoma NRAS_Q61R NF1 46 218 Male -1.20 -2.04 -0.46 1596.20 1.00 403 39 211 7 TRUE 2.59
melanoma NRAS_Q61R NF1 82 297 Sex:overall -1.29 -2.58 -0.04 1476.92 1.00 679 73 288 9 TRUE 1.39
melanoma NRAS_Q61R FLT1 37 28 Female 0.44 -0.52 1.43 1327.06 1.00 315 32 23 5 FALSE 0.42
melanoma NRAS_Q61R FLT1 47 94 Male 0.03 -0.82 0.75 1431.68 1.00 470 40 87 7 FALSE 0.03
melanoma NRAS_Q61R FLT1 84 122 Sex:overall 0.25 -1.06 1.64 1450.09 1.00 785 72 110 12 FALSE 0.14
melanoma NRAS_Q61R RPTOR 36 15 Female -1.02 -2.85 0.48 1081.37 1.00 322 35 14 1 FALSE 0.62
melanoma NRAS_Q61R RPTOR 45 36 Male -1.14 -3.09 0.28 1216.48 1.00 502 44 35 1 FALSE 0.74
melanoma NRAS_Q61R RPTOR 81 51 Sex:overall -1.06 -2.99 0.61 1060.21 1.00 824 79 49 2 FALSE 0.60
melanoma NRAS_Q61R SF3B1 36 44 Female -0.12 -1.11 0.80 992.71 1.00 297 31 39 5 TRUE 0.10
melanoma NRAS_Q61R SF3B1 45 48 Male -0.44 -1.63 0.54 1173.15 1.00 489 43 46 2 TRUE 0.38
melanoma NRAS_Q61R SF3B1 81 92 Sex:overall -0.27 -1.57 1.00 1189.82 1.00 786 74 85 7 TRUE 0.16
melanoma NRAS_Q61R ROS1 36 68 Female -0.34 -1.19 0.45 1401.25 1.00 298 31 63 5 TRUE 0.38
melanoma NRAS_Q61R ROS1 48 186 Male -0.35 -1.05 0.24 1506.28 1.00 420 37 175 11 TRUE 0.55
melanoma NRAS_Q61R ROS1 84 254 Sex:overall -0.34 -1.51 0.81 1617.35 1.00 718 68 238 16 TRUE 0.25
melanoma NRAS_Q61R FLT3 37 27 Female 0.22 -0.65 1.05 814.44 1.00 322 33 23 4 TRUE 0.20
melanoma NRAS_Q61R FLT3 45 53 Male 0.08 -0.84 0.90 813.38 1.00 500 41 49 4 TRUE 0.07
melanoma NRAS_Q61R FLT3 82 80 Sex:overall 0.14 -0.98 1.06 988.73 1.00 822 74 72 8 TRUE 0.11
melanoma NRAS_Q61R AXL 36 15 Female -1.19 -3.18 0.47 417.43 1.01 324 35 14 1 FALSE 0.66
melanoma NRAS_Q61R AXL 45 48 Male -1.41 -3.32 0.05 586.15 1.00 494 44 47 1 FALSE 0.96
melanoma NRAS_Q61R AXL 81 63 Sex:overall -1.31 -3.34 0.51 596.83 1.00 818 79 61 2 FALSE 0.72
melanoma NRAS_Q61R PIK3CG 36 27 Female -0.96 -2.48 0.24 1127.40 1.00 314 35 26 1 FALSE 0.77
melanoma NRAS_Q61R PIK3CG 45 79 Male -0.74 -1.76 0.30 257.70 1.02 483 41 75 4 FALSE 0.74
melanoma NRAS_Q61R PIK3CG 81 106 Sex:overall -0.82 -2.39 0.56 943.66 1.00 797 76 101 5 FALSE 0.58
melanoma NRAS_Q61R EGFR 37 20 Female -0.40 -1.80 0.74 576.36 1.01 325 35 18 2 TRUE 0.29
melanoma NRAS_Q61R EGFR 45 47 Male -0.54 -1.90 0.40 84.91 1.06 507 43 45 2 TRUE 0.43
melanoma NRAS_Q61R EGFR 82 67 Sex:overall -0.48 -1.90 0.76 467.76 1.02 832 78 63 4 TRUE 0.32
melanoma NRAS_Q61R ARID1B 36 19 Female 0.23 -0.87 1.37 1332.14 1.00 322 33 16 3 TRUE 0.17
melanoma NRAS_Q61R ARID1B 45 56 Male -0.02 -1.07 0.87 1272.95 1.00 498 41 52 4 TRUE 0.01
melanoma NRAS_Q61R ARID1B 81 75 Sex:overall 0.10 -1.35 1.52 1396.44 1.00 820 74 68 7 TRUE 0.05
melanoma NRAS_Q61R GNA11 37 20 Female -1.92 -5.12 -0.19 33.22 1.05 323 37 20 0 TRUE 0.82
melanoma NRAS_Q61R GNA11 45 34 Male -1.72 -4.50 -0.20 36.28 1.05 512 44 33 1 TRUE 0.84
melanoma NRAS_Q61R GNA11 82 54 Sex:overall -1.80 -4.75 -0.07 33.07 1.05 835 81 53 1 TRUE 0.83
melanoma NRAS_Q61R INSR 36 21 Female 0.59 -0.52 1.67 1219.00 1.00 308 31 16 5 FALSE 0.53
melanoma NRAS_Q61R INSR 42 46 Male -0.18 -1.51 0.93 1397.70 1.00 474 40 44 2 FALSE 0.11
melanoma NRAS_Q61R INSR 78 67 Sex:overall 0.23 -1.26 1.67 1391.42 1.00 782 71 60 7 FALSE 0.12
melanoma NRAS_Q61R ERG 36 11 Female -1.57 -4.42 0.65 1488.91 1.00 328 35 10 1 FALSE 0.62
melanoma NRAS_Q61R ERG 45 42 Male -2.53 -6.36 -0.37 1410.37 1.00 499 45 42 0 FALSE 0.96
melanoma NRAS_Q61R ERG 81 53 Sex:overall -1.98 -5.16 0.41 1380.41 1.00 827 80 52 1 FALSE 0.79
melanoma NRAS_Q61R MET 37 24 Female -0.67 -2.15 0.41 904.96 1.00 322 36 23 1 TRUE 0.51
melanoma NRAS_Q61R MET 45 61 Male -0.42 -1.46 0.52 1109.94 1.00 494 41 57 4 TRUE 0.39
melanoma NRAS_Q61R MET 82 85 Sex:overall -0.54 -1.94 0.70 1337.46 1.00 816 77 80 5 TRUE 0.36
melanoma NRAS_Q61R BRAF 37 99 Female -2.71 -4.25 -1.50 1588.41 1.00 248 36 98 1 TRUE 3.75
melanoma NRAS_Q61R BRAF 45 200 Male -2.69 -4.17 -1.57 1313.06 1.00 364 43 198 2 TRUE 4.31
thyroid cancer NRAS_Q61R BRAF 32 76 Female -4.01 -6.51 -2.21 831.60 1.00 115 31 75 1 TRUE 3.50
thyroid cancer NRAS_Q61R BRAF 32 97 Male -4.25 -7.35 -2.43 829.28 1.01 139 32 97 0 TRUE 3.16
melanoma NRAS_Q61R BRAF 82 299 Sex:overall -2.67 -4.25 -1.37 1260.25 1.00 612 79 296 3 TRUE 3.31
thyroid cancer NRAS_Q61R BRAF 64 173 Sex:overall -4.09 -6.90 -2.19 808.44 1.00 254 63 172 1 TRUE 3.22
melanoma NRAS_Q61R TET2 36 23 Female -0.09 -1.33 1.12 1426.20 1.00 318 33 20 3 TRUE 0.05
melanoma NRAS_Q61R TET2 45 69 Male -0.52 -1.71 0.43 1557.85 1.00 482 42 66 3 TRUE 0.47
melanoma NRAS_Q61R TET2 81 92 Sex:overall -0.32 -1.83 1.16 1462.38 1.00 800 75 86 6 TRUE 0.17
melanoma NRAS_Q61R PDGFRB 45 57 Male -2.10 -4.70 -0.26 669.57 1.00 495 44 56 1 TRUE 1.14
melanoma NRAS_Q61R PDGFRB 45 57 Sex:overall -1.80 -6.20 3.41 930.01 1.00 495 44 56 1 TRUE 0.37
melanoma NRAS_Q61R CARD11 36 28 Female -1.18 -2.83 0.09 1514.10 1.00 315 35 27 1 FALSE 0.93
melanoma NRAS_Q61R CARD11 45 84 Male -1.04 -2.24 -0.03 1445.41 1.00 470 42 81 3 FALSE 1.17
melanoma NRAS_Q61R CARD11 81 112 Sex:overall -1.10 -2.76 0.32 1498.17 1.00 785 77 108 4 FALSE 0.79
melanoma NRAS_Q61R CBL 36 27 Female -0.17 -1.33 0.99 80.14 1.01 315 32 23 4 TRUE 0.11
melanoma NRAS_Q61R CBL 45 56 Male -0.85 -2.55 0.19 1012.33 1.00 486 44 55 1 TRUE 0.66
melanoma NRAS_Q61R CBL 81 83 Sex:overall -0.48 -1.94 0.93 528.53 1.01 801 76 78 5 TRUE 0.30
melanoma NRAS_Q61R TP63 37 45 Female 0.35 -0.51 1.17 1614.24 1.00 293 30 38 7 FALSE 0.39
melanoma NRAS_Q61R TP63 44 126 Male -0.02 -0.74 0.68 1488.98 1.00 415 35 117 9 FALSE 0.02
melanoma NRAS_Q61R TP63 81 171 Sex:overall 0.16 -1.06 1.42 1564.25 1.00 708 65 155 16 FALSE 0.10
melanoma NRAS_Q61R GLI1 35 14 Female -0.36 -2.00 1.16 1419.35 1.00 305 33 12 2 FALSE 0.18
melanoma NRAS_Q61R GLI1 44 48 Male -1.10 -2.92 0.16 1408.60 1.00 466 43 47 1 FALSE 0.79
melanoma NRAS_Q61R GLI1 79 62 Sex:overall -0.70 -2.70 1.18 1463.87 1.00 771 76 59 3 FALSE 0.34
melanoma NRAS_Q61R ZFHX3 35 29 Female 0.05 -1.11 1.11 1318.14 1.00 294 31 25 4 FALSE 0.03
melanoma NRAS_Q61R ZFHX3 45 116 Male -0.60 -1.50 0.22 1571.34 1.00 447 40 111 5 FALSE 0.76
melanoma NRAS_Q61R ZFHX3 80 145 Sex:overall -0.30 -1.86 1.36 1560.49 1.00 741 71 136 9 FALSE 0.14
melanoma NRAS_Q61R MGA 35 23 Female -1.93 -5.08 -0.14 1595.43 1.00 294 35 23 0 FALSE 0.90
melanoma NRAS_Q61R MGA 44 73 Male -1.17 -2.59 0.03 1428.78 1.00 451 41 70 3 FALSE 1.10
melanoma NRAS_Q61R MGA 79 96 Sex:overall -1.52 -3.70 0.16 1574.66 1.00 745 76 93 3 FALSE 0.91
melanoma NRAS_Q61R KMT2B 22 17 Female 0.10 -1.37 1.34 638.07 1.01 160 19 14 3 FALSE 0.05
melanoma NRAS_Q61R KMT2B 30 78 Male -0.54 -1.71 0.42 651.41 1.00 261 26 74 4 FALSE 0.51
melanoma NRAS_Q61R KMT2B 52 95 Sex:overall -0.19 -1.93 1.68 872.48 1.00 421 45 88 7 FALSE 0.08
melanoma NRAS_Q61R ANKRD11 35 21 Female -0.26 -1.70 1.08 1513.70 1.00 288 32 18 3 FALSE 0.15
melanoma NRAS_Q61R ANKRD11 41 55 Male -1.07 -2.92 0.20 1526.48 1.00 434 40 54 1 FALSE 0.75
melanoma NRAS_Q61R ANKRD11 76 76 Sex:overall -0.62 -2.39 1.13 1495.42 1.00 722 72 72 4 FALSE 0.32
melanoma NRAS_Q61R PGR 35 14 Female -1.84 -4.88 0.34 1059.58 1.00 291 34 13 1 FALSE 0.81
melanoma NRAS_Q61R PGR 41 42 Male -2.57 -6.09 -0.33 951.93 1.00 437 41 42 0 FALSE 1.03
melanoma NRAS_Q61R PGR 76 56 Sex:overall -2.13 -5.16 0.15 923.77 1.00 728 75 55 1 FALSE 0.91
melanoma NRAS_Q61R PLCG2 35 20 Female -0.40 -1.98 0.69 892.14 1.00 287 34 19 1 FALSE 0.26
melanoma NRAS_Q61R PLCG2 41 43 Male -0.14 -1.32 0.80 1028.45 1.00 440 37 39 4 FALSE 0.10
melanoma NRAS_Q61R PLCG2 76 63 Sex:overall -0.29 -1.82 0.95 966.73 1.00 727 71 58 5 FALSE 0.17
melanoma NRAS_Q61R PREX2 21 43 Female -0.07 -0.94 0.86 1549.61 1.00 144 16 38 5 FALSE 0.05
melanoma NRAS_Q61R PREX2 31 133 Male -0.32 -1.07 0.40 1465.56 1.00 244 23 125 8 FALSE 0.39
melanoma NRAS_Q61R PREX2 52 176 Sex:overall -0.18 -1.39 0.96 1502.36 1.00 388 39 163 13 FALSE 0.11
melanoma NRAS_Q61R EPHA7 35 28 Female -2.37 -6.32 -0.42 1296.40 1.00 290 35 28 0 FALSE 0.82
melanoma NRAS_Q61R EPHA7 44 131 Male -1.09 -2.10 -0.18 1403.40 1.00 417 39 126 5 FALSE 1.57
melanoma NRAS_Q61R EPHA7 79 159 Sex:overall -1.64 -4.36 0.52 1407.47 1.00 707 74 154 5 FALSE 0.74
pancreatic cancer KRAS_G12R TP53 89 449 Female 0.67 0.27 1.05 241.04 1.01 289 22 382 67 TRUE 3.30
pancreatic cancer KRAS_G12R TP53 91 497 Male 0.57 0.16 0.88 36.72 1.05 310 30 436 61 TRUE 2.27
pancreatic cancer KRAS_G12R TP53 180 946 Sex:overall 0.62 0.15 1.05 93.12 1.02 599 52 818 128 TRUE 2.00
pancreatic cancer KRAS_G12R RNF43 85 34 Female -0.15 -1.00 0.63 241.22 1.01 611 82 31 3 TRUE 0.16
pancreatic cancer KRAS_G12R RNF43 87 46 Male -0.05 -0.76 0.73 79.24 1.02 688 81 40 6 TRUE 0.04
pancreatic cancer KRAS_G12R RNF43 172 80 Sex:overall -0.11 -1.00 0.73 200.46 1.01 1299 163 71 9 TRUE 0.10
pancreatic cancer KRAS_G12R ARID1A 85 62 Female -1.22 -2.31 -0.35 757.24 1.00 586 82 59 3 TRUE 1.88
pancreatic cancer KRAS_G12R ARID1A 87 65 Male -1.27 -2.45 -0.41 725.76 1.00 666 85 63 2 TRUE 1.86
pancreatic cancer KRAS_G12R ARID1A 172 127 Sex:overall -1.24 -2.39 -0.31 786.89 1.00 1252 167 122 5 TRUE 1.72
pancreatic cancer KRAS_G12R KDM6A 85 21 Female -0.09 -1.22 0.92 1082.23 1.00 624 82 18 3 FALSE 0.06
pancreatic cancer KRAS_G12R KDM6A 87 38 Male -0.25 -1.37 0.68 995.52 1.00 689 84 35 3 FALSE 0.21
pancreatic cancer KRAS_G12R KDM6A 172 59 Sex:overall -0.14 -1.31 1.02 1152.95 1.00 1313 166 53 6 FALSE 0.09
pancreatic cancer KRAS_G12R CDKN2A 91 134 Female 0.56 0.11 1.05 1110.49 1.00 568 65 108 26 TRUE 1.89
pancreatic cancer KRAS_G12R CDKN2A 92 160 Male 0.37 -0.10 0.75 622.15 1.00 610 72 140 20 TRUE 1.00
pancreatic cancer KRAS_G12R CDKN2A 183 294 Sex:overall 0.46 -0.12 1.02 1251.93 1.00 1178 137 248 46 TRUE 0.84
pancreatic cancer KRAS_G12R SMAD4 90 136 Female 0.75 0.38 1.16 698.36 1.00 562 62 108 28 TRUE 3.68
pancreatic cancer KRAS_G12R SMAD4 92 139 Male 0.68 0.27 1.04 841.91 1.00 630 69 116 23 TRUE 3.12
pancreatic cancer KRAS_G12R SMAD4 182 275 Sex:overall 0.72 0.26 1.19 993.11 1.00 1192 131 224 51 TRUE 2.18
pancreatic cancer KRAS_G12R KMT2D 85 26 Female -0.70 -2.03 0.33 832.72 1.00 618 84 25 1 FALSE 0.59
pancreatic cancer KRAS_G12R KMT2D 88 40 Male -0.47 -1.70 0.45 757.19 1.00 693 84 36 4 FALSE 0.42
pancreatic cancer KRAS_G12R KMT2D 173 66 Sex:overall -0.58 -1.89 0.62 924.62 1.00 1311 168 61 5 FALSE 0.43
pancreatic cancer KRAS_G12R GNAS 89 25 Female 0.08 -1.09 1.10 1426.91 1.00 647 84 20 5 TRUE 0.05
pancreatic cancer KRAS_G12R GNAS 91 37 Male -0.70 -2.75 0.46 1067.99 1.00 710 90 36 1 TRUE 0.42
pancreatic cancer KRAS_G12R GNAS 180 62 Sex:overall -0.30 -2.13 1.03 1459.46 1.00 1357 174 56 6 TRUE 0.16
pancreatic cancer KRAS_G12R DAXX 82 21 Female -6.92 -11.63 -1.76 2.97 1.40 594 82 21 0 TRUE 1.60
pancreatic cancer KRAS_G12R DAXX 81 32 Male -6.91 -11.29 -1.75 2.94 1.41 667 81 32 0 TRUE 1.60
pancreatic cancer KRAS_G12R DAXX 163 53 Sex:overall -6.88 -11.36 -1.69 2.92 1.42 1261 163 53 0 TRUE 1.57
pancreatic cancer KRAS_G12R MEN1 85 36 Female -5.89 -12.14 -1.96 540.44 1.01 606 85 36 0 TRUE 1.50
pancreatic cancer KRAS_G12R MEN1 87 41 Male -5.90 -12.39 -1.90 557.73 1.01 683 87 41 0 TRUE 1.51
pancreatic cancer KRAS_G12R MEN1 172 77 Sex:overall -5.85 -11.97 -1.88 548.62 1.01 1289 172 77 0 TRUE 1.49
pancreatic cancer KRAS_Q61H TP53 29 449 Female 0.79 0.18 1.44 280.25 1.01 305 6 426 23 TRUE 1.76
pancreatic cancer KRAS_Q61H TP53 31 497 Male 0.72 0.10 1.37 567.89 1.00 331 9 475 22 TRUE 1.55
pancreatic cancer KRAS_Q61H TP53 60 946 Sex:overall 0.75 0.08 1.45 576.45 1.00 636 15 901 45 TRUE 1.26
pancreatic cancer KRAS_Q61H RNF43 27 34 Female -1.57 -4.30 0.38 590.71 1.01 667 26 33 1 TRUE 0.69
pancreatic cancer KRAS_Q61H RNF43 31 46 Male -1.83 -4.74 0.22 758.64 1.01 738 31 46 0 TRUE 0.79
pancreatic cancer KRAS_Q61H RNF43 58 80 Sex:overall -1.68 -4.37 0.32 585.53 1.01 1405 57 79 1 TRUE 0.76
pancreatic cancer KRAS_Q61H ARID1A 27 62 Female 0.33 -0.75 1.11 27.87 1.12 645 23 58 4 TRUE 0.30
pancreatic cancer KRAS_Q61H ARID1A 32 65 Male 0.18 -1.01 0.91 17.68 1.18 721 30 63 2 TRUE 0.13
pancreatic cancer KRAS_Q61H ARID1A 59 127 Sex:overall 0.25 -0.96 1.18 27.31 1.12 1366 53 121 6 TRUE 0.18
pancreatic cancer KRAS_Q61H KDM6A 27 21 Female -0.76 -3.56 0.88 1287.50 1.00 679 27 21 0 FALSE 0.28
pancreatic cancer KRAS_Q61H KDM6A 31 38 Male -0.31 -2.14 1.11 1381.92 1.00 744 29 36 2 FALSE 0.15
pancreatic cancer KRAS_Q61H KDM6A 58 59 Sex:overall -0.50 -2.90 1.28 1272.85 1.00 1423 56 57 2 FALSE 0.20
pancreatic cancer KRAS_Q61H CDKN2A 28 134 Female -0.17 -1.00 0.58 497.80 1.01 609 24 130 4 TRUE 0.17
pancreatic cancer KRAS_Q61H CDKN2A 31 160 Male -0.13 -0.99 0.62 402.44 1.01 657 25 154 6 TRUE 0.13
pancreatic cancer KRAS_Q61H CDKN2A 59 294 Sex:overall -0.16 -1.02 0.64 495.08 1.01 1266 49 284 10 TRUE 0.15
pancreatic cancer KRAS_Q61H SMAD4 29 136 Female 0.20 -0.63 0.89 1172.54 1.00 600 24 131 5 TRUE 0.22
pancreatic cancer KRAS_Q61H SMAD4 31 139 Male 0.32 -0.43 1.02 1225.05 1.00 676 23 131 8 TRUE 0.44
pancreatic cancer KRAS_Q61H SMAD4 60 275 Sex:overall 0.26 -0.60 1.04 1088.63 1.00 1276 47 262 13 TRUE 0.26
pancreatic cancer KRAS_Q61H KMT2D 27 26 Female -1.55 -4.50 0.35 1158.12 1.00 675 27 26 0 FALSE 0.64
pancreatic cancer KRAS_Q61H KMT2D 31 40 Male -1.34 -3.86 0.55 1250.11 1.00 747 30 39 1 FALSE 0.64
pancreatic cancer KRAS_Q61H KMT2D 58 66 Sex:overall -1.44 -4.21 0.57 1281.92 1.00 1422 57 65 1 FALSE 0.62
pancreatic cancer KRAS_Q61H GNAS 28 25 Female 0.09 -1.53 1.29 1117.26 1.00 704 27 24 1 TRUE 0.05
pancreatic cancer KRAS_Q61H GNAS 31 37 Male 0.16 -1.43 1.31 1288.37 1.00 771 29 35 2 TRUE 0.08
pancreatic cancer KRAS_Q61H GNAS 59 62 Sex:overall 0.13 -1.48 1.36 1325.67 1.00 1475 56 59 3 TRUE 0.06
pancreatic cancer KRAS_Q61H DAXX 27 21 Female -4.81 -11.69 -0.48 579.09 1.00 649 27 21 0 TRUE 0.96
pancreatic cancer KRAS_Q61H DAXX 31 32 Male -4.85 -11.55 -0.59 650.91 1.01 717 31 32 0 TRUE 0.98
pancreatic cancer KRAS_Q61H DAXX 58 53 Sex:overall -4.75 -11.28 -0.41 596.12 1.01 1366 58 53 0 TRUE 0.96
pancreatic cancer KRAS_Q61H MEN1 27 36 Female -5.00 -10.65 -0.89 447.61 1.02 664 27 36 0 TRUE 1.30
pancreatic cancer KRAS_Q61H MEN1 31 41 Male -5.01 -10.75 -0.97 378.74 1.02 739 31 41 0 TRUE 1.31
pancreatic cancer KRAS_Q61H MEN1 58 77 Sex:overall -4.95 -10.59 -0.81 378.13 1.02 1403 58 77 0 TRUE 1.30
colorectal cancer KRAS_G12S APC 33 1110 Female 0.48 -0.17 1.28 653.90 1.00 417 7 1084 26 TRUE 0.74
colorectal cancer KRAS_G12S APC 34 1428 Male 0.50 -0.16 1.26 887.68 1.01 462 5 1399 29 TRUE 0.77
colorectal cancer KRAS_G12S APC 67 2538 Sex:overall 0.49 -0.39 1.40 770.97 1.00 879 12 2483 55 TRUE 0.56
colorectal cancer KRAS_G12A SPEN 22 45 Metastasis -1.19 -4.02 0.54 599.38 1.01 820 22 45 0 FALSE 0.47
colorectal cancer KRAS_G12A SPEN 29 110 Primary -0.71 -2.53 0.65 951.89 1.01 1236 27 108 2 FALSE 0.44
non-small cell lung cancer KRAS_G12A SPEN 25 71 Metastasis -0.09 -2.09 1.28 1546.43 1.00 1315 24 70 1 FALSE 0.04
non-small cell lung cancer KRAS_G12A SPEN 63 50 Primary 0.48 -0.87 1.61 1567.98 1.00 2192 60 47 3 FALSE 0.35
colorectal cancer KRAS_G12A SPEN 51 155 Tumor Type:overall -0.92 -3.25 0.76 795.77 1.01 2056 49 153 2 FALSE 0.44
non-small cell lung cancer KRAS_G12A SPEN 88 121 Tumor Type:overall 0.18 -1.77 1.96 1572.81 1.00 3507 84 117 4 FALSE 0.07
non-small cell lung cancer KRAS_G12A KMT2C 25 89 Metastasis -1.11 -3.71 0.37 922.88 1.00 1277 25 89 0 FALSE 0.54
non-small cell lung cancer KRAS_G12A KMT2C 63 133 Primary -0.70 -2.19 0.48 978.31 1.00 2114 60 130 3 FALSE 0.56
non-small cell lung cancer KRAS_G12A KMT2C 88 222 Tumor Type:overall -0.89 -2.71 0.49 1239.32 1.00 3391 85 219 3 FALSE 0.55
colorectal cancer KRAS_G12A TP53 23 701 Metastasis -0.52 -1.23 0.14 1533.95 1.00 281 9 687 14 TRUE 0.94
colorectal cancer KRAS_G12A TP53 32 1018 Primary -0.66 -1.26 -0.09 1363.97 1.00 548 17 1003 15 TRUE 1.57
non-small cell lung cancer KRAS_G12A TP53 25 855 Metastasis -0.73 -1.37 -0.07 1386.82 1.00 610 14 844 11 TRUE 1.54
non-small cell lung cancer KRAS_G12A TP53 68 1201 Primary -0.86 -1.36 -0.36 1528.01 1.00 1221 49 1182 19 TRUE 3.07
colorectal cancer KRAS_G12A TP53 55 1719 Tumor Type:overall -0.58 -1.44 0.29 1232.90 1.00 829 26 1690 29 TRUE 0.79
non-small cell lung cancer KRAS_G12A TP53 93 2056 Tumor Type:overall -0.80 -1.66 0.10 1608.77 1.00 1831 63 2026 30 TRUE 0.99
colorectal cancer KRAS_G12A ATRX 22 33 Metastasis 0.75 -0.92 2.19 1360.14 1.00 830 19 30 3 TRUE 0.45
colorectal cancer KRAS_G12A ATRX 28 86 Primary -1.38 -5.93 0.73 1274.11 1.00 1243 28 86 0 TRUE 0.35
non-small cell lung cancer KRAS_G12A ATRX 25 79 Metastasis -0.66 -3.70 0.72 928.59 1.00 1289 25 79 0 TRUE 0.23
non-small cell lung cancer KRAS_G12A ATRX 64 129 Primary 0.01 -1.03 0.95 1414.18 1.00 2127 59 124 5 TRUE 0.01
colorectal cancer KRAS_G12A ATRX 50 119 Tumor Type:overall -0.24 -3.27 2.31 1483.60 1.00 2073 47 116 3 TRUE 0.07
non-small cell lung cancer KRAS_G12A ATRX 89 208 Tumor Type:overall -0.32 -2.46 1.00 1301.43 1.00 3416 84 203 5 TRUE 0.15
colorectal cancer KRAS_G12A ATR 22 30 Metastasis -4.60 -11.47 -0.34 257.49 1.02 834 22 30 0 FALSE 0.91
colorectal cancer KRAS_G12A ATR 28 84 Primary -4.60 -11.47 -0.56 275.26 1.02 1251 28 84 0 FALSE 0.94
non-small cell lung cancer KRAS_G12A ATR 25 53 Metastasis 0.28 -1.19 1.34 1078.77 1.01 1307 24 52 1 FALSE 0.18
non-small cell lung cancer KRAS_G12A ATR 64 76 Primary 0.45 -0.66 1.37 1146.56 1.00 2165 60 72 4 FALSE 0.41
colorectal cancer KRAS_G12A ATR 50 114 Tumor Type:overall -4.52 -11.08 -0.35 280.68 1.02 2085 50 114 0 FALSE 0.92
non-small cell lung cancer KRAS_G12A ATR 89 129 Tumor Type:overall 0.36 -1.07 1.49 1212.17 1.00 3472 84 124 5 FALSE 0.22
colorectal cancer KRAS_G12A PDGFRA 23 15 Metastasis -4.55 -12.72 -0.11 203.96 1.01 916 23 15 0 TRUE 0.81
colorectal cancer KRAS_G12A PDGFRA 32 45 Primary -4.58 -12.56 -0.26 225.85 1.01 1424 32 45 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A PDGFRA 25 64 Metastasis -0.36 -2.04 0.99 1571.77 1.00 1347 24 63 1 TRUE 0.20
non-small cell lung cancer KRAS_G12A PDGFRA 66 84 Primary -0.36 -1.75 0.82 1224.66 1.00 2231 64 82 2 TRUE 0.23
colorectal cancer KRAS_G12A PDGFRA 55 60 Tumor Type:overall -4.48 -12.19 -0.07 211.60 1.01 2340 55 60 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A PDGFRA 91 148 Tumor Type:overall -0.38 -2.08 0.99 1424.30 1.00 3578 88 145 3 TRUE 0.20
colorectal cancer KRAS_G12A FBXW7 23 90 Metastasis 0.47 -0.57 1.37 1392.47 1.00 855 20 87 3 TRUE 0.47
colorectal cancer KRAS_G12A FBXW7 33 249 Primary 0.71 0.00 1.40 1568.72 1.00 1257 23 239 10 TRUE 1.29
non-small cell lung cancer KRAS_G12A FBXW7 25 32 Metastasis -0.98 -3.87 1.18 1032.91 1.00 1378 24 31 1 TRUE 0.35
non-small cell lung cancer KRAS_G12A FBXW7 66 54 Primary -1.55 -4.62 0.43 1175.91 1.00 2257 66 54 0 TRUE 0.58
colorectal cancer KRAS_G12A FBXW7 56 339 Tumor Type:overall 0.58 -0.73 1.77 1583.08 1.00 2112 43 326 13 TRUE 0.44
non-small cell lung cancer KRAS_G12A FBXW7 91 86 Tumor Type:overall -1.22 -4.12 0.86 1034.73 1.00 3635 90 85 1 TRUE 0.46
colorectal cancer KRAS_G12A MAP3K1 22 30 Metastasis -1.47 -4.80 0.73 646.50 1.00 828 22 30 0 FALSE 0.48
colorectal cancer KRAS_G12A MAP3K1 28 62 Primary -1.25 -4.05 0.70 376.44 1.00 1260 27 61 1 FALSE 0.50
non-small cell lung cancer KRAS_G12A MAP3K1 25 30 Metastasis 0.03 -2.03 1.55 929.95 1.00 1329 24 29 1 FALSE 0.01
non-small cell lung cancer KRAS_G12A MAP3K1 63 37 Primary -0.09 -2.14 1.32 815.94 1.00 2200 62 36 1 FALSE 0.04
colorectal cancer KRAS_G12A MAP3K1 50 92 Tumor Type:overall -1.33 -4.43 0.77 400.77 1.00 2088 49 91 1 FALSE 0.50
non-small cell lung cancer KRAS_G12A MAP3K1 88 67 Tumor Type:overall -0.01 -2.13 1.63 829.94 1.00 3529 86 65 2 FALSE 0.00
colorectal cancer KRAS_G12A NSD1 22 23 Metastasis -4.79 -11.31 -0.11 1194.39 1.00 835 22 23 0 FALSE 0.96
colorectal cancer KRAS_G12A NSD1 28 63 Primary -4.87 -11.67 -0.54 1166.95 1.00 1261 28 63 0 FALSE 0.99
non-small cell lung cancer KRAS_G12A NSD1 25 34 Metastasis 0.11 -2.34 1.43 798.16 1.00 1324 25 34 0 FALSE 0.04
non-small cell lung cancer KRAS_G12A NSD1 63 56 Primary 0.61 -0.53 1.64 112.44 1.04 2183 59 52 4 FALSE 0.59
colorectal cancer KRAS_G12A NSD1 50 86 Tumor Type:overall -4.70 -11.07 -0.23 1121.35 1.00 2096 50 86 0 FALSE 0.98
non-small cell lung cancer KRAS_G12A NSD1 88 90 Tumor Type:overall 0.36 -1.35 1.73 1173.51 1.01 3507 84 86 4 FALSE 0.17
colorectal cancer KRAS_G12A FLT4 22 41 Metastasis -0.68 -2.71 0.95 1426.62 1.00 818 21 40 1 TRUE 0.34
colorectal cancer KRAS_G12A FLT4 28 98 Primary -0.79 -2.76 0.66 1154.83 1.00 1231 27 97 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A FLT4 26 37 Metastasis 0.50 -0.78 1.67 1347.84 1.00 1322 24 35 2 TRUE 0.37
non-small cell lung cancer KRAS_G12A FLT4 63 65 Primary 0.31 -0.89 1.36 1328.45 1.00 2175 61 63 2 TRUE 0.22
colorectal cancer KRAS_G12A FLT4 50 139 Tumor Type:overall -0.71 -2.86 1.06 1353.20 1.00 2049 48 137 2 TRUE 0.33
non-small cell lung cancer KRAS_G12A FLT4 89 102 Tumor Type:overall 0.41 -0.96 1.72 1450.39 1.00 3497 85 98 4 TRUE 0.27
colorectal cancer KRAS_G12A PTPRD 22 28 Metastasis 0.96 -0.56 2.29 1233.41 1.00 835 19 25 3 FALSE 0.72
colorectal cancer KRAS_G12A PTPRD 28 75 Primary 0.06 -1.81 1.33 1317.16 1.00 1255 27 74 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A PTPRD 25 165 Metastasis -0.03 -1.22 0.84 1424.90 1.00 1224 23 163 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A PTPRD 64 226 Primary 0.38 -0.30 1.02 1242.06 1.00 2048 54 216 10 FALSE 0.57
colorectal cancer KRAS_G12A PTPRD 50 103 Tumor Type:overall 0.47 -1.49 2.05 1409.40 1.00 2090 46 99 4 FALSE 0.22
non-small cell lung cancer KRAS_G12A PTPRD 89 391 Tumor Type:overall 0.18 -1.04 1.25 1463.09 1.00 3272 77 379 12 FALSE 0.12
colorectal cancer KRAS_G12A RET 23 20 Metastasis -4.56 -11.53 -0.07 1273.08 1.00 911 23 20 0 TRUE 0.86
colorectal cancer KRAS_G12A RET 32 45 Primary -4.60 -12.12 -0.11 1228.69 1.00 1422 32 45 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A RET 25 39 Metastasis -0.17 -2.08 1.12 858.84 1.01 1368 24 38 1 TRUE 0.08
non-small cell lung cancer KRAS_G12A RET 66 54 Primary -0.25 -2.12 0.94 50.81 1.04 2258 65 53 1 TRUE 0.13
colorectal cancer KRAS_G12A RET 55 65 Tumor Type:overall -4.51 -11.54 -0.11 1247.90 1.00 2333 55 65 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A RET 91 93 Tumor Type:overall -0.23 -2.17 1.08 163.07 1.02 3626 89 91 2 TRUE 0.11
colorectal cancer KRAS_G12A KDM5A 22 24 Metastasis -4.78 -11.79 -0.48 786.95 1.00 841 22 24 0 FALSE 0.94
colorectal cancer KRAS_G12A KDM5A 28 72 Primary -4.82 -11.90 -0.58 813.48 1.00 1249 28 72 0 FALSE 0.97
non-small cell lung cancer KRAS_G12A KDM5A 25 24 Metastasis 0.68 -0.99 2.17 983.56 1.00 1335 23 22 2 FALSE 0.40
non-small cell lung cancer KRAS_G12A KDM5A 63 49 Primary 0.17 -1.41 1.51 1337.59 1.00 2191 62 48 1 FALSE 0.09
colorectal cancer KRAS_G12A KDM5A 50 96 Tumor Type:overall -4.70 -11.58 -0.40 826.65 1.00 2090 50 96 0 FALSE 0.95
non-small cell lung cancer KRAS_G12A KDM5A 88 73 Tumor Type:overall 0.41 -1.33 1.99 1298.24 1.00 3526 85 70 3 FALSE 0.19
colorectal cancer KRAS_G12A PIK3C2G 22 20 Metastasis -0.20 -4.32 1.67 1253.19 1.00 839 22 20 0 FALSE 0.05
colorectal cancer KRAS_G12A PIK3C2G 29 67 Primary 0.83 -0.32 1.87 1429.58 1.00 1260 25 63 4 FALSE 0.84
non-small cell lung cancer KRAS_G12A PIK3C2G 25 52 Metastasis 0.60 -0.58 1.61 1319.00 1.00 1310 23 50 2 FALSE 0.54
non-small cell lung cancer KRAS_G12A PIK3C2G 63 79 Primary 0.61 -0.40 1.49 896.64 1.00 2165 59 75 4 FALSE 0.67
colorectal cancer KRAS_G12A PIK3C2G 51 87 Tumor Type:overall 0.34 -2.68 2.31 1374.56 1.00 2099 47 83 4 FALSE 0.11
non-small cell lung cancer KRAS_G12A PIK3C2G 88 131 Tumor Type:overall 0.59 -0.67 1.63 1263.32 1.00 3475 82 125 6 FALSE 0.49
non-small cell lung cancer KRAS_G12A TSHR 25 34 Metastasis -0.01 -2.03 1.51 1283.12 1.00 1326 24 33 1 TRUE 0.00
non-small cell lung cancer KRAS_G12A TSHR 63 35 Primary -0.09 -2.12 1.37 1367.66 1.00 2202 62 34 1 TRUE 0.04
non-small cell lung cancer KRAS_G12A TSHR 88 69 Tumor Type:overall -0.02 -2.11 1.64 1287.77 1.00 3528 86 67 2 TRUE 0.01
colorectal cancer KRAS_G12A CREBBP 22 37 Metastasis -0.74 -2.99 1.03 1383.60 1.00 828 21 36 1 TRUE 0.33
colorectal cancer KRAS_G12A CREBBP 28 151 Primary -1.17 -3.01 0.28 1354.35 1.00 1200 27 150 1 TRUE 0.79
non-small cell lung cancer KRAS_G12A CREBBP 25 67 Metastasis -0.12 -1.72 1.17 1335.29 1.00 1300 23 65 2 TRUE 0.06
non-small cell lung cancer KRAS_G12A CREBBP 63 75 Primary -0.51 -2.16 0.74 1352.25 1.00 2163 62 74 1 TRUE 0.30
colorectal cancer KRAS_G12A CREBBP 50 188 Tumor Type:overall -0.97 -3.20 0.93 1515.98 1.00 2028 48 186 2 TRUE 0.45
non-small cell lung cancer KRAS_G12A CREBBP 88 142 Tumor Type:overall -0.31 -2.15 1.14 1357.46 1.00 3463 85 139 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A BRIP1 25 30 Metastasis 0.01 -3.00 1.48 381.34 1.00 1327 25 30 0 TRUE 0.00
non-small cell lung cancer KRAS_G12A BRIP1 63 40 Primary 0.60 -0.87 1.78 323.44 1.00 2199 60 37 3 TRUE 0.41
non-small cell lung cancer KRAS_G12A BRIP1 88 70 Tumor Type:overall 0.32 -1.83 1.75 372.52 1.00 3526 85 67 3 TRUE 0.13
colorectal cancer KRAS_G12A AXIN2 22 26 Metastasis 1.11 -0.24 2.36 1415.46 1.00 835 19 23 3 TRUE 0.97
colorectal cancer KRAS_G12A AXIN2 28 89 Primary 0.32 -1.06 1.40 1451.63 1.00 1241 26 87 2 TRUE 0.21
non-small cell lung cancer KRAS_G12A AXIN2 25 26 Metastasis -1.06 -4.57 0.99 805.38 1.00 1331 25 26 0 TRUE 0.34
non-small cell lung cancer KRAS_G12A AXIN2 63 36 Primary -0.80 -3.55 1.01 871.84 1.00 2200 62 35 1 TRUE 0.29
colorectal cancer KRAS_G12A AXIN2 50 115 Tumor Type:overall 0.72 -1.03 2.60 1474.40 1.00 2076 45 110 5 TRUE 0.37
non-small cell lung cancer KRAS_G12A AXIN2 88 62 Tumor Type:overall -0.93 -4.00 1.03 766.57 1.00 3531 87 61 1 TRUE 0.32
colorectal cancer KRAS_G12A DOT1L 23 23 Metastasis 0.31 -1.71 2.11 1338.03 1.00 838 21 21 2 FALSE 0.12
colorectal cancer KRAS_G12A DOT1L 28 61 Primary -1.03 -4.87 0.96 1183.89 1.00 1260 28 61 0 FALSE 0.29
non-small cell lung cancer KRAS_G12A DOT1L 25 46 Metastasis -0.49 -2.37 1.00 1108.72 1.00 1313 24 45 1 FALSE 0.24
non-small cell lung cancer KRAS_G12A DOT1L 63 61 Primary -0.60 -2.47 0.82 1050.24 1.00 2177 62 60 1 FALSE 0.33
colorectal cancer KRAS_G12A DOT1L 51 84 Tumor Type:overall -0.35 -3.15 1.78 1337.82 1.00 2098 49 82 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A DOT1L 88 107 Tumor Type:overall -0.52 -2.44 1.08 1207.97 1.00 3490 86 105 2 FALSE 0.24
non-small cell lung cancer KRAS_G12A PTPRS 25 32 Metastasis -0.89 -3.82 1.09 790.75 1.01 1331 24 31 1 FALSE 0.32
non-small cell lung cancer KRAS_G12A PTPRS 63 48 Primary -1.33 -4.72 0.71 390.29 1.01 2188 63 48 0 FALSE 0.46
non-small cell lung cancer KRAS_G12A PTPRS 88 80 Tumor Type:overall -1.10 -4.19 0.90 505.74 1.01 3519 87 79 1 FALSE 0.40
colorectal cancer KRAS_G12A SMARCA4 23 40 Metastasis 1.14 -0.07 2.23 1412.22 1.00 825 19 36 4 FALSE 1.24
colorectal cancer KRAS_G12A SMARCA4 29 129 Primary 0.28 -0.92 1.23 1330.95 1.00 1217 26 126 3 FALSE 0.21
non-small cell lung cancer KRAS_G12A SMARCA4 25 149 Metastasis -0.38 -1.53 0.59 1399.29 1.00 1220 23 147 2 FALSE 0.30
non-small cell lung cancer KRAS_G12A SMARCA4 63 164 Primary -0.28 -1.34 0.60 1595.16 1.00 2087 59 160 4 FALSE 0.24
colorectal cancer KRAS_G12A SMARCA4 52 169 Tumor Type:overall 0.68 -1.01 2.23 1180.15 1.00 2042 45 162 7 FALSE 0.37
non-small cell lung cancer KRAS_G12A SMARCA4 88 313 Tumor Type:overall -0.32 -1.56 0.86 1525.59 1.00 3307 82 307 6 FALSE 0.21
colorectal cancer KRAS_G12A PTPRT 22 58 Metastasis -0.74 -3.36 0.95 143.35 1.02 804 20 56 2 FALSE 0.33
colorectal cancer KRAS_G12A PTPRT 28 127 Primary -1.72 -5.01 0.14 651.00 1.00 1202 28 127 0 FALSE 0.64
non-small cell lung cancer KRAS_G12A PTPRT 27 150 Metastasis 0.10 -0.72 1.04 692.61 1.02 1240 22 145 5 FALSE 0.09
non-small cell lung cancer KRAS_G12A PTPRT 63 201 Primary -0.26 -1.31 0.45 29.68 1.05 2069 60 198 3 FALSE 0.25
colorectal cancer KRAS_G12A PTPRT 50 185 Tumor Type:overall -1.23 -3.69 0.68 359.34 1.01 2006 48 183 2 FALSE 0.51
non-small cell lung cancer KRAS_G12A PTPRT 90 351 Tumor Type:overall -0.08 -1.14 0.96 1474.57 1.00 3309 82 343 8 FALSE 0.06
colorectal cancer KRAS_G12A HGF 22 22 Metastasis -4.52 -10.95 -0.03 828.12 1.00 834 22 22 0 FALSE 0.95
colorectal cancer KRAS_G12A HGF 28 34 Primary -4.51 -10.74 -0.07 833.94 1.00 1283 28 34 0 FALSE 0.96
non-small cell lung cancer KRAS_G12A HGF 25 72 Metastasis -0.07 -1.45 0.94 1246.93 1.00 1288 24 71 1 FALSE 0.04
non-small cell lung cancer KRAS_G12A HGF 63 119 Primary 0.04 -1.03 0.94 1123.48 1.00 2131 59 115 4 FALSE 0.03
colorectal cancer KRAS_G12A HGF 50 56 Tumor Type:overall -4.47 -10.81 0.00 857.02 1.00 2117 50 56 0 FALSE 0.95
non-small cell lung cancer KRAS_G12A HGF 88 191 Tumor Type:overall 0.00 -1.32 1.09 1190.55 1.00 3419 83 186 5 FALSE 0.00
colorectal cancer KRAS_G12A BLM 22 14 Metastasis -4.63 -12.27 0.11 1432.69 1.00 846 22 14 0 TRUE 0.84
colorectal cancer KRAS_G12A BLM 28 56 Primary -4.77 -12.29 -0.16 1331.87 1.00 1261 28 56 0 TRUE 0.88
colorectal cancer KRAS_G12A BLM 50 70 Tumor Type:overall -4.54 -11.71 0.08 1378.92 1.00 2107 50 70 0 TRUE 0.86
colorectal cancer KRAS_G12A PIK3CA 23 151 Metastasis 0.05 -0.89 0.87 1359.73 1.00 793 19 147 4 TRUE 0.04
colorectal cancer KRAS_G12A PIK3CA 33 360 Primary 0.02 -0.73 0.70 1246.39 1.00 1159 25 352 8 TRUE 0.02
non-small cell lung cancer KRAS_G12A PIK3CA 25 80 Metastasis -0.72 -3.77 0.69 1178.61 1.00 1329 25 80 0 TRUE 0.27
non-small cell lung cancer KRAS_G12A PIK3CA 67 162 Primary 0.05 -0.99 0.92 1341.39 1.00 2157 61 156 6 TRUE 0.04
colorectal cancer KRAS_G12A PIK3CA 56 511 Tumor Type:overall 0.03 -1.06 1.08 1386.21 1.00 1952 44 499 12 TRUE 0.02
non-small cell lung cancer KRAS_G12A PIK3CA 92 242 Tumor Type:overall -0.32 -2.52 1.12 1398.71 1.00 3486 86 236 6 TRUE 0.13
non-small cell lung cancer KRAS_G12A GATA3 25 26 Metastasis -1.10 -4.38 1.04 1456.42 1.00 1332 25 26 0 FALSE 0.37
non-small cell lung cancer KRAS_G12A GATA3 63 40 Primary -0.88 -3.71 0.94 1271.61 1.00 2199 62 39 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A GATA3 88 66 Tumor Type:overall -0.98 -4.10 1.11 1424.74 1.00 3531 87 65 1 FALSE 0.34
colorectal cancer KRAS_G12A ESR1 22 22 Metastasis -0.82 -4.07 1.31 807.95 1.01 835 21 21 1 TRUE 0.26
colorectal cancer KRAS_G12A ESR1 28 50 Primary -1.24 -4.48 0.78 663.14 1.00 1266 28 50 0 TRUE 0.42
non-small cell lung cancer KRAS_G12A ESR1 25 17 Metastasis -5.08 -11.62 0.00 39.58 1.05 1341 25 17 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A ESR1 63 39 Primary -5.16 -11.53 -0.26 43.64 1.05 2198 63 39 0 TRUE 0.89
colorectal cancer KRAS_G12A ESR1 50 72 Tumor Type:overall -1.01 -4.07 1.11 668.26 1.01 2101 49 71 1 TRUE 0.33
non-small cell lung cancer KRAS_G12A ESR1 88 56 Tumor Type:overall -5.03 -11.41 0.04 40.49 1.05 3539 88 56 0 TRUE 0.88
colorectal cancer KRAS_G12A ALK 23 37 Metastasis -1.47 -3.61 0.67 22.78 1.10 895 22 36 1 TRUE 0.66
colorectal cancer KRAS_G12A ALK 32 78 Primary -1.77 -4.26 0.25 54.80 1.05 1402 32 78 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A ALK 25 67 Metastasis -1.65 -4.55 0.40 575.58 1.01 1345 24 66 1 TRUE 0.74
non-small cell lung cancer KRAS_G12A ALK 66 102 Primary -2.12 -5.42 -0.08 639.49 1.01 2211 66 102 0 TRUE 0.86
colorectal cancer KRAS_G12A ALK 55 115 Tumor Type:overall -1.61 -3.90 0.54 31.74 1.07 2297 54 114 1 TRUE 0.75
non-small cell lung cancer KRAS_G12A ALK 91 169 Tumor Type:overall -1.87 -4.92 0.21 473.23 1.01 3556 90 168 1 TRUE 0.77
colorectal cancer KRAS_G12A RNF43 22 64 Metastasis -2.58 -6.40 -0.29 1328.41 1.00 806 22 64 0 TRUE 0.98
colorectal cancer KRAS_G12A RNF43 28 203 Primary -2.26 -5.11 -0.36 1437.36 1.00 1165 27 202 1 TRUE 1.21
colorectal cancer KRAS_G12A RNF43 50 267 Tumor Type:overall -2.41 -5.71 -0.16 1367.76 1.00 1971 49 266 1 TRUE 1.07
non-small cell lung cancer KRAS_G12A U2AF1 25 30 Metastasis 0.53 -2.89 1.77 322.36 1.02 1328 25 30 0 FALSE 0.18
non-small cell lung cancer KRAS_G12A U2AF1 64 48 Primary 1.29 0.37 2.18 200.77 1.03 2193 58 42 6 FALSE 2.44
non-small cell lung cancer KRAS_G12A U2AF1 89 78 Tumor Type:overall 0.93 -1.13 2.05 702.63 1.00 3521 83 72 6 FALSE 0.61
non-small cell lung cancer KRAS_G12A LATS1 25 28 Metastasis -1.26 -4.55 0.92 1146.26 1.00 1329 25 28 0 FALSE 0.43
non-small cell lung cancer KRAS_G12A LATS1 63 40 Primary -1.00 -3.83 0.92 981.61 1.00 2197 62 39 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A LATS1 88 68 Tumor Type:overall -1.12 -4.26 0.94 1181.54 1.00 3526 87 67 1 FALSE 0.41
non-small cell lung cancer KRAS_G12A LATS2 25 23 Metastasis -4.57 -11.64 -0.04 1018.81 1.00 1334 25 23 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A LATS2 63 38 Primary -4.62 -11.54 -0.25 937.88 1.00 2200 63 38 0 FALSE 0.90
non-small cell lung cancer KRAS_G12A LATS2 88 61 Tumor Type:overall -4.52 -11.70 -0.25 946.71 1.00 3534 88 61 0 FALSE 0.89
colorectal cancer KRAS_G12A PTEN 23 43 Metastasis -0.84 -2.96 0.83 1559.54 1.00 894 22 42 1 TRUE 0.42
colorectal cancer KRAS_G12A PTEN 32 142 Primary -1.12 -3.17 0.28 1576.34 1.00 1364 31 141 1 TRUE 0.71
non-small cell lung cancer KRAS_G12A PTEN 25 51 Metastasis -0.59 -2.67 0.74 42.04 1.07 1358 24 50 1 TRUE 0.28
non-small cell lung cancer KRAS_G12A PTEN 66 85 Primary -0.72 -2.86 0.51 33.87 1.09 2228 65 84 1 TRUE 0.34
colorectal cancer KRAS_G12A PTEN 55 185 Tumor Type:overall -0.95 -3.15 0.96 1563.11 1.00 2258 53 183 2 TRUE 0.45
non-small cell lung cancer KRAS_G12A PTEN 91 136 Tumor Type:overall -0.66 -2.87 0.78 44.83 1.08 3586 89 134 2 TRUE 0.30
colorectal cancer KRAS_G12A BCOR 22 18 Metastasis -0.68 -3.96 1.69 1568.63 1.00 840 21 17 1 FALSE 0.19
colorectal cancer KRAS_G12A BCOR 28 94 Primary -2.18 -6.37 0.16 1390.52 1.00 1235 28 94 0 FALSE 0.68
non-small cell lung cancer KRAS_G12A BCOR 25 54 Metastasis -0.68 -2.65 0.89 1137.21 1.00 1308 24 53 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A BCOR 63 80 Primary -0.81 -2.77 0.57 1182.49 1.00 2163 62 79 1 FALSE 0.47
colorectal cancer KRAS_G12A BCOR 50 112 Tumor Type:overall -1.31 -4.61 1.58 1438.38 1.00 2075 49 111 1 FALSE 0.39
non-small cell lung cancer KRAS_G12A BCOR 88 134 Tumor Type:overall -0.73 -2.73 0.74 1320.07 1.00 3471 86 132 2 FALSE 0.38
colorectal cancer KRAS_G12A CTNNB1 23 44 Metastasis -0.10 -1.68 1.29 1378.75 1.00 889 21 42 2 TRUE 0.05
colorectal cancer KRAS_G12A CTNNB1 32 119 Primary -0.63 -2.25 0.68 1457.93 1.00 1354 31 118 1 TRUE 0.38
non-small cell lung cancer KRAS_G12A CTNNB1 25 55 Metastasis -0.15 -1.96 1.18 1011.47 1.00 1353 24 54 1 TRUE 0.07
non-small cell lung cancer KRAS_G12A CTNNB1 66 66 Primary -0.12 -1.62 1.05 1309.27 1.00 2245 64 64 2 TRUE 0.07
colorectal cancer KRAS_G12A CTNNB1 55 163 Tumor Type:overall -0.35 -2.11 1.32 1528.26 1.00 2243 52 160 3 TRUE 0.16
non-small cell lung cancer KRAS_G12A CTNNB1 91 121 Tumor Type:overall -0.16 -1.94 1.26 1196.81 1.00 3598 88 118 3 TRUE 0.07
colorectal cancer KRAS_G12A ARID1A 22 73 Metastasis -0.82 -2.55 0.55 1476.44 1.00 806 21 72 1 TRUE 0.52
colorectal cancer KRAS_G12A ARID1A 28 242 Primary -0.73 -1.99 0.34 1347.03 1.00 1147 25 239 3 TRUE 0.64
non-small cell lung cancer KRAS_G12A ARID1A 26 129 Metastasis -0.61 -1.90 0.52 1383.91 1.00 1243 24 127 2 TRUE 0.49
non-small cell lung cancer KRAS_G12A ARID1A 63 155 Primary -0.76 -2.08 0.29 1588.89 1.00 2093 61 153 2 TRUE 0.70
colorectal cancer KRAS_G12A ARID1A 50 315 Tumor Type:overall -0.76 -2.56 0.86 1484.34 1.00 1953 46 311 4 TRUE 0.42
non-small cell lung cancer KRAS_G12A ARID1A 89 284 Tumor Type:overall -0.68 -2.15 0.54 1642.85 1.00 3336 85 280 4 TRUE 0.48
colorectal cancer KRAS_G12A PIK3R1 22 27 Metastasis -1.84 -5.62 0.48 1022.79 1.00 834 22 27 0 TRUE 0.63
colorectal cancer KRAS_G12A PIK3R1 28 89 Primary -1.45 -4.33 0.38 1045.95 1.00 1238 27 88 1 TRUE 0.64
non-small cell lung cancer KRAS_G12A PIK3R1 25 12 Metastasis -4.49 -12.17 0.11 1273.76 1.00 1346 25 12 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A PIK3R1 63 43 Primary -4.59 -11.86 -0.24 1137.18 1.00 2193 63 43 0 TRUE 0.88
colorectal cancer KRAS_G12A PIK3R1 50 116 Tumor Type:overall -1.60 -4.68 0.44 1121.38 1.00 2072 49 115 1 TRUE 0.62
non-small cell lung cancer KRAS_G12A PIK3R1 88 55 Tumor Type:overall -4.45 -11.57 0.02 1167.68 1.00 3539 88 55 0 TRUE 0.86
colorectal cancer KRAS_G12A IKZF1 22 24 Metastasis -4.49 -12.05 -0.21 210.27 1.01 834 22 24 0 TRUE 0.83
colorectal cancer KRAS_G12A IKZF1 28 62 Primary -4.51 -12.16 -0.24 206.22 1.01 1254 28 62 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A IKZF1 25 36 Metastasis 0.23 -1.59 1.62 750.59 1.00 1322 24 35 1 TRUE 0.11
non-small cell lung cancer KRAS_G12A IKZF1 63 46 Primary 0.28 -1.32 1.42 508.49 1.01 2193 61 44 2 TRUE 0.16
colorectal cancer KRAS_G12A IKZF1 50 86 Tumor Type:overall -4.40 -11.45 -0.06 192.92 1.01 2088 50 86 0 TRUE 0.84
non-small cell lung cancer KRAS_G12A IKZF1 88 82 Tumor Type:overall 0.26 -1.50 1.59 817.58 1.00 3515 85 79 3 TRUE 0.13
colorectal cancer KRAS_G12A TERT 22 27 Metastasis -0.97 -3.58 1.03 1065.32 1.01 834 21 26 1 TRUE 0.38
colorectal cancer KRAS_G12A TERT 28 71 Primary -1.53 -5.31 0.36 169.98 1.03 1249 28 71 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A TERT 25 61 Metastasis 0.10 -1.11 1.12 1320.15 1.00 1302 24 60 1 TRUE 0.06
non-small cell lung cancer KRAS_G12A TERT 63 105 Primary 0.18 -0.84 1.08 866.78 1.00 2138 59 101 4 TRUE 0.15
colorectal cancer KRAS_G12A TERT 50 98 Tumor Type:overall -1.20 -4.20 0.78 320.69 1.02 2083 49 97 1 TRUE 0.46
non-small cell lung cancer KRAS_G12A TERT 88 166 Tumor Type:overall 0.14 -1.16 1.23 1387.11 1.00 3440 83 161 5 TRUE 0.09
colorectal cancer KRAS_G12A FAT1 22 62 Metastasis 0.33 -0.75 1.44 1166.04 1.00 818 19 59 3 FALSE 0.26
colorectal cancer KRAS_G12A FAT1 29 165 Primary -0.02 -1.12 0.91 1657.31 1.00 1205 26 162 3 FALSE 0.01
non-small cell lung cancer KRAS_G12A FAT1 25 123 Metastasis -0.48 -1.67 0.58 1197.86 1.00 1243 23 121 2 FALSE 0.39
non-small cell lung cancer KRAS_G12A FAT1 63 182 Primary -0.56 -1.62 0.38 1294.39 1.00 2081 60 179 3 FALSE 0.56
colorectal cancer KRAS_G12A FAT1 51 227 Tumor Type:overall 0.19 -1.12 1.48 1277.10 1.00 2023 45 221 6 FALSE 0.10
non-small cell lung cancer KRAS_G12A FAT1 88 305 Tumor Type:overall -0.54 -1.86 0.63 1303.21 1.00 3324 83 300 5 FALSE 0.40
colorectal cancer KRAS_G12A FGFR4 28 46 Primary -0.51 -3.41 1.49 1310.44 1.00 1273 27 45 1 TRUE 0.16
colorectal cancer KRAS_G12A FGFR4 28 46 Tumor Type:overall -0.45 -5.53 4.35 1450.77 1.00 1273 27 45 1 TRUE 0.07
colorectal cancer KRAS_G12A CIC 22 37 Metastasis -0.20 -1.91 1.22 1372.09 1.00 826 21 36 1 TRUE 0.09
colorectal cancer KRAS_G12A CIC 29 100 Primary -0.19 -1.62 1.01 1431.13 1.00 1237 27 98 2 TRUE 0.11
non-small cell lung cancer KRAS_G12A CIC 25 53 Metastasis 0.03 -1.84 1.40 1548.56 1.00 1314 24 52 1 TRUE 0.01
non-small cell lung cancer KRAS_G12A CIC 63 39 Primary 0.27 -1.31 1.53 1325.68 1.00 2201 61 37 2 TRUE 0.14
colorectal cancer KRAS_G12A CIC 51 137 Tumor Type:overall -0.19 -1.86 1.29 1426.33 1.00 2063 48 134 3 TRUE 0.08
non-small cell lung cancer KRAS_G12A CIC 88 92 Tumor Type:overall 0.14 -1.79 1.91 1420.68 1.00 3515 85 89 3 TRUE 0.05
colorectal cancer KRAS_G12A KDM6A 22 13 Metastasis -0.51 -4.41 1.62 1450.15 1.00 844 22 13 0 FALSE 0.13
colorectal cancer KRAS_G12A KDM6A 28 49 Primary 0.23 -1.77 1.61 1420.35 1.00 1269 26 47 2 FALSE 0.11
non-small cell lung cancer KRAS_G12A KDM6A 26 23 Metastasis 0.77 -0.82 2.22 1234.86 1.00 1336 24 21 2 FALSE 0.50
non-small cell lung cancer KRAS_G12A KDM6A 63 38 Primary 0.40 -1.36 1.67 1156.31 1.00 2201 62 37 1 FALSE 0.22
colorectal cancer KRAS_G12A KDM6A 50 62 Tumor Type:overall -0.12 -2.90 1.93 1249.33 1.00 2113 48 60 2 FALSE 0.04
non-small cell lung cancer KRAS_G12A KDM6A 89 61 Tumor Type:overall 0.60 -1.07 2.10 1202.34 1.00 3537 86 58 3 FALSE 0.34
colorectal cancer KRAS_G12A NCOR1 22 37 Metastasis 0.08 -1.57 1.48 1427.07 1.00 825 20 35 2 FALSE 0.04
colorectal cancer KRAS_G12A NCOR1 28 98 Primary -0.41 -2.29 0.88 1453.29 1.00 1238 27 97 1 FALSE 0.21
non-small cell lung cancer KRAS_G12A NCOR1 25 52 Metastasis -0.65 -4.93 1.30 1309.91 1.00 1313 25 52 0 FALSE 0.14
non-small cell lung cancer KRAS_G12A NCOR1 63 52 Primary 1.01 -0.18 2.00 1340.89 1.00 2190 58 47 5 FALSE 1.17
colorectal cancer KRAS_G12A NCOR1 50 135 Tumor Type:overall -0.15 -1.96 1.50 1616.84 1.00 2063 47 132 3 FALSE 0.06
non-small cell lung cancer KRAS_G12A NCOR1 88 104 Tumor Type:overall 0.22 -2.75 2.04 1514.95 1.00 3503 83 99 5 FALSE 0.07
colorectal cancer KRAS_G12A POLE 22 28 Metastasis 0.39 -1.40 1.91 1576.81 1.00 831 20 26 2 TRUE 0.19
colorectal cancer KRAS_G12A POLE 28 113 Primary -0.62 -2.66 0.76 1240.06 1.00 1228 27 112 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A POLE 25 59 Metastasis -0.07 -1.59 1.30 1281.49 1.00 1302 23 57 2 TRUE 0.03
non-small cell lung cancer KRAS_G12A POLE 63 77 Primary -0.42 -2.05 0.84 914.61 1.00 2166 62 76 1 TRUE 0.25
colorectal cancer KRAS_G12A POLE 50 141 Tumor Type:overall -0.16 -2.29 1.74 1420.63 1.00 2059 47 138 3 TRUE 0.06
non-small cell lung cancer KRAS_G12A POLE 88 136 Tumor Type:overall -0.26 -1.90 1.28 809.50 1.00 3468 85 133 3 TRUE 0.12
non-small cell lung cancer KRAS_G12A CUL3 25 26 Metastasis -0.78 -3.65 1.32 766.70 1.00 1333 24 25 1 FALSE 0.28
non-small cell lung cancer KRAS_G12A CUL3 63 51 Primary -1.38 -4.65 0.60 342.66 1.01 2191 63 51 0 FALSE 0.47
non-small cell lung cancer KRAS_G12A CUL3 88 77 Tumor Type:overall -1.07 -4.12 1.05 538.46 1.01 3524 87 76 1 FALSE 0.37
colorectal cancer KRAS_G12A ABL1 23 17 Metastasis -5.17 -11.99 -0.24 70.27 1.06 915 23 17 0 TRUE 0.98
colorectal cancer KRAS_G12A ABL1 32 56 Primary -5.16 -12.03 -0.37 65.74 1.06 1416 32 56 0 TRUE 0.99
colorectal cancer KRAS_G12A ABL1 55 73 Tumor Type:overall -5.05 -12.12 -0.10 58.88 1.06 2331 55 73 0 TRUE 0.97
colorectal cancer KRAS_G12A FOXP1 22 15 Metastasis -1.34 -5.29 1.10 1539.31 1.00 841 22 15 0 FALSE 0.39
colorectal cancer KRAS_G12A FOXP1 28 55 Primary -0.92 -3.71 1.02 1431.83 1.00 1264 27 54 1 FALSE 0.34
colorectal cancer KRAS_G12A FOXP1 50 70 Tumor Type:overall -1.12 -4.44 1.21 1441.79 1.00 2105 49 69 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A NOTCH2 25 40 Metastasis -4.86 -11.85 -0.56 1279.63 1.00 1321 25 40 0 TRUE 1.01
non-small cell lung cancer KRAS_G12A NOTCH2 63 75 Primary -4.89 -11.70 -0.71 1226.63 1.00 2167 63 75 0 TRUE 1.04
non-small cell lung cancer KRAS_G12A NOTCH2 88 115 Tumor Type:overall -4.83 -11.61 -0.55 1256.44 1.00 3488 88 115 0 TRUE 1.03
non-small cell lung cancer KRAS_G12A DDR2 25 45 Metastasis -4.89 -12.06 -0.52 505.95 1.00 1312 25 45 0 TRUE 0.97
non-small cell lung cancer KRAS_G12A DDR2 63 53 Primary -4.89 -12.47 -0.77 512.13 1.00 2182 63 53 0 TRUE 0.98
non-small cell lung cancer KRAS_G12A DDR2 88 98 Tumor Type:overall -4.80 -12.04 -0.54 481.79 1.00 3494 88 98 0 TRUE 0.99
colorectal cancer KRAS_G12A TGFBR2 22 26 Metastasis -1.78 -5.43 0.48 1426.75 1.00 830 22 26 0 TRUE 0.62
colorectal cancer KRAS_G12A TGFBR2 28 88 Primary -1.39 -3.92 0.49 1451.89 1.00 1232 27 87 1 TRUE 0.64
non-small cell lung cancer KRAS_G12A TGFBR2 25 27 Metastasis -4.56 -11.76 0.00 1368.38 1.00 1332 25 27 0 TRUE 0.83
non-small cell lung cancer KRAS_G12A TGFBR2 63 29 Primary -4.61 -11.78 -0.10 1348.53 1.00 2208 63 29 0 TRUE 0.85
colorectal cancer KRAS_G12A TGFBR2 50 114 Tumor Type:overall -1.59 -4.67 0.59 1486.36 1.00 2062 49 113 1 TRUE 0.61
non-small cell lung cancer KRAS_G12A TGFBR2 88 56 Tumor Type:overall -4.50 -11.41 -0.04 1373.98 1.00 3540 88 56 0 TRUE 0.85
colorectal cancer KRAS_G12A SMO 23 19 Metastasis -4.85 -12.19 -0.03 396.89 1.01 911 23 19 0 TRUE 0.85
colorectal cancer KRAS_G12A SMO 32 52 Primary -4.90 -12.14 -0.18 427.93 1.01 1420 32 52 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A SMO 25 29 Metastasis -0.51 -3.17 1.24 1156.82 1.00 1378 25 29 0 TRUE 0.17
non-small cell lung cancer KRAS_G12A SMO 66 46 Primary -0.09 -2.02 1.33 651.39 1.00 2265 64 44 2 TRUE 0.04
colorectal cancer KRAS_G12A SMO 55 71 Tumor Type:overall -4.77 -11.85 0.03 396.85 1.01 2331 55 71 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A SMO 91 75 Tumor Type:overall -0.26 -2.57 1.41 1059.94 1.00 3643 89 73 2 TRUE 0.10
colorectal cancer KRAS_G12A KMT2A 22 37 Metastasis -5.19 -12.14 -0.84 799.11 1.00 826 22 37 0 FALSE 1.11
colorectal cancer KRAS_G12A KMT2A 28 111 Primary -5.18 -12.44 -0.98 873.84 1.00 1229 28 111 0 FALSE 1.10
non-small cell lung cancer KRAS_G12A KMT2A 25 53 Metastasis -1.75 -5.20 0.26 294.66 1.02 1308 25 53 0 FALSE 0.72
non-small cell lung cancer KRAS_G12A KMT2A 63 61 Primary -1.47 -4.01 0.44 151.03 1.02 2178 62 60 1 FALSE 0.68
colorectal cancer KRAS_G12A KMT2A 50 148 Tumor Type:overall -5.03 -12.11 -0.87 845.80 1.00 2055 50 148 0 FALSE 1.12
non-small cell lung cancer KRAS_G12A KMT2A 88 114 Tumor Type:overall -1.59 -4.41 0.48 227.10 1.02 3486 87 113 1 FALSE 0.68
colorectal cancer KRAS_G12A JAK3 23 22 Metastasis -0.54 -3.21 1.30 292.91 1.00 911 22 21 1 TRUE 0.19
colorectal cancer KRAS_G12A JAK3 32 41 Primary -0.89 -4.27 0.92 199.01 1.01 1427 32 41 0 TRUE 0.28
non-small cell lung cancer KRAS_G12A JAK3 25 23 Metastasis -0.62 -3.66 1.26 1012.52 1.00 1384 25 23 0 TRUE 0.21
non-small cell lung cancer KRAS_G12A JAK3 66 60 Primary -0.23 -2.10 1.08 1232.05 1.00 2251 64 58 2 TRUE 0.11
colorectal cancer KRAS_G12A JAK3 55 63 Tumor Type:overall -0.68 -3.57 1.27 232.10 1.00 2338 54 62 1 TRUE 0.23
non-small cell lung cancer KRAS_G12A JAK3 91 83 Tumor Type:overall -0.42 -2.73 1.37 1008.87 1.00 3635 89 81 2 TRUE 0.16
non-small cell lung cancer KRAS_G12A PAK7 25 61 Metastasis -0.76 -3.56 0.82 1416.54 1.00 1300 25 61 0 FALSE 0.26
non-small cell lung cancer KRAS_G12A PAK7 64 72 Primary -0.09 -1.57 1.01 1325.21 1.00 2171 61 69 3 FALSE 0.05
non-small cell lung cancer KRAS_G12A PAK7 89 133 Tumor Type:overall -0.41 -2.66 1.08 1330.47 1.00 3471 86 130 3 FALSE 0.17
non-small cell lung cancer KRAS_G12A STAG2 25 43 Metastasis 0.72 -0.82 1.75 1217.41 1.00 1319 24 42 1 TRUE 0.60
non-small cell lung cancer KRAS_G12A STAG2 63 59 Primary 0.99 0.00 1.84 986.89 1.00 2183 58 54 5 TRUE 1.46
non-small cell lung cancer KRAS_G12A STAG2 88 102 Tumor Type:overall 0.84 -0.58 1.98 1206.00 1.00 3502 82 96 6 TRUE 0.70
colorectal cancer KRAS_G12A BRCA2 22 48 Metastasis -1.22 -4.74 0.58 1197.77 1.00 818 22 48 0 TRUE 0.40
colorectal cancer KRAS_G12A BRCA2 30 142 Primary -0.42 -1.79 0.69 1554.46 1.00 1225 27 139 3 TRUE 0.28
non-small cell lung cancer KRAS_G12A BRCA2 25 67 Metastasis -0.08 -1.75 1.13 1510.61 1.00 1299 24 66 1 TRUE 0.04
non-small cell lung cancer KRAS_G12A BRCA2 63 68 Primary 0.19 -1.09 1.24 1409.46 1.00 2174 60 65 3 TRUE 0.13
colorectal cancer KRAS_G12A BRCA2 52 190 Tumor Type:overall -0.79 -3.01 0.85 1399.13 1.00 2043 49 187 3 TRUE 0.35
non-small cell lung cancer KRAS_G12A BRCA2 88 135 Tumor Type:overall 0.06 -1.55 1.42 1531.78 1.00 3473 84 131 4 TRUE 0.03
colorectal cancer KRAS_G12A NOTCH3 22 58 Metastasis 0.32 -0.92 1.47 1457.22 1.00 811 19 55 3 TRUE 0.23
colorectal cancer KRAS_G12A NOTCH3 28 142 Primary -0.16 -1.50 0.85 1496.38 1.00 1205 26 140 2 TRUE 0.10
non-small cell lung cancer KRAS_G12A NOTCH3 25 51 Metastasis -0.23 -1.85 1.11 768.39 1.00 1309 24 50 1 TRUE 0.12
non-small cell lung cancer KRAS_G12A NOTCH3 63 77 Primary -0.21 -1.58 0.96 795.11 1.00 2167 61 75 2 TRUE 0.13
colorectal cancer KRAS_G12A NOTCH3 50 200 Tumor Type:overall 0.10 -1.33 1.50 1381.97 1.00 2016 45 195 5 TRUE 0.05
non-small cell lung cancer KRAS_G12A NOTCH3 88 128 Tumor Type:overall -0.22 -1.79 1.14 873.13 1.00 3476 85 125 3 TRUE 0.11
non-small cell lung cancer KRAS_G12A NOTCH4 25 55 Metastasis -0.30 -1.88 0.92 1108.24 1.00 1305 24 54 1 TRUE 0.17
non-small cell lung cancer KRAS_G12A NOTCH4 63 84 Primary -0.30 -1.74 0.79 1152.60 1.00 2157 61 82 2 TRUE 0.19
non-small cell lung cancer KRAS_G12A NOTCH4 88 139 Tumor Type:overall -0.29 -1.91 0.96 1048.74 1.00 3462 85 136 3 TRUE 0.16
colorectal cancer KRAS_G12A FGFR3 23 14 Metastasis -1.08 -4.34 1.17 937.40 1.00 917 23 14 0 TRUE 0.34
colorectal cancer KRAS_G12A FGFR3 32 46 Primary -0.78 -3.34 1.09 388.77 1.01 1424 31 45 1 TRUE 0.30
colorectal cancer KRAS_G12A FGFR3 55 60 Tumor Type:overall -0.88 -3.70 1.28 437.05 1.01 2341 54 59 1 TRUE 0.31
non-small cell lung cancer KRAS_G12A MAP3K13 25 23 Metastasis -0.99 -4.66 1.21 1164.75 1.00 1335 25 23 0 FALSE 0.28
non-small cell lung cancer KRAS_G12A MAP3K13 63 29 Primary -0.64 -3.57 1.22 1166.94 1.00 2207 62 28 1 FALSE 0.23
non-small cell lung cancer KRAS_G12A MAP3K13 88 52 Tumor Type:overall -0.79 -4.08 1.37 1009.50 1.00 3542 87 51 1 FALSE 0.25
colorectal cancer KRAS_G12A IGF1R 22 22 Metastasis -1.27 -4.87 0.89 703.21 1.00 838 22 22 0 TRUE 0.40
colorectal cancer KRAS_G12A IGF1R 28 58 Primary -1.01 -4.16 0.85 664.32 1.00 1262 27 57 1 TRUE 0.37
non-small cell lung cancer KRAS_G12A IGF1R 25 26 Metastasis -5.72 -14.31 0.02 8.47 1.33 1332 25 26 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A IGF1R 63 28 Primary -5.74 -14.52 -0.12 8.60 1.32 2207 63 28 0 TRUE 0.73
colorectal cancer KRAS_G12A IGF1R 50 80 Tumor Type:overall -1.12 -4.61 0.90 767.95 1.00 2100 49 79 1 TRUE 0.37
non-small cell lung cancer KRAS_G12A IGF1R 88 54 Tumor Type:overall -5.67 -14.35 -0.10 8.15 1.35 3539 88 54 0 TRUE 0.72
non-small cell lung cancer KRAS_G12A KEAP1 26 234 Metastasis 0.63 -0.18 1.44 1560.65 1.00 1140 17 225 9 FALSE 0.89
non-small cell lung cancer KRAS_G12A KEAP1 63 304 Primary 0.00 -0.75 0.66 1403.84 1.00 1952 56 297 7 FALSE 0.00
non-small cell lung cancer KRAS_G12A KEAP1 89 538 Tumor Type:overall 0.31 -0.86 1.54 1520.07 1.00 3092 73 522 16 FALSE 0.21
colorectal cancer KRAS_G12A KDM5C 22 14 Metastasis -4.57 -11.77 0.37 1213.67 1.00 843 22 14 0 FALSE 0.81
colorectal cancer KRAS_G12A KDM5C 28 55 Primary -4.66 -11.98 -0.13 1269.76 1.00 1269 28 55 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A KDM5C 25 41 Metastasis -0.74 -3.53 0.93 1339.88 1.00 1317 25 41 0 FALSE 0.28
non-small cell lung cancer KRAS_G12A KDM5C 63 65 Primary -0.42 -2.09 0.96 1398.58 1.00 2176 61 63 2 FALSE 0.24
colorectal cancer KRAS_G12A KDM5C 50 69 Tumor Type:overall -4.47 -11.46 0.08 1265.44 1.00 2112 50 69 0 FALSE 0.84
non-small cell lung cancer KRAS_G12A KDM5C 88 106 Tumor Type:overall -0.56 -2.77 1.06 1365.32 1.00 3493 86 104 2 FALSE 0.26
non-small cell lung cancer KRAS_G12A CDKN2A 25 92 Metastasis -0.15 -1.33 0.95 1374.73 1.00 1323 23 90 2 TRUE 0.11
non-small cell lung cancer KRAS_G12A CDKN2A 67 184 Primary -0.26 -1.24 0.56 1373.57 1.00 2137 63 180 4 TRUE 0.24
non-small cell lung cancer KRAS_G12A CDKN2A 92 276 Tumor Type:overall -0.21 -1.37 0.87 1407.21 1.00 3460 86 270 6 TRUE 0.14
colorectal cancer KRAS_G12A EPHB1 22 25 Metastasis -4.65 -13.40 -0.33 39.53 1.08 831 22 25 0 FALSE 0.75
colorectal cancer KRAS_G12A EPHB1 28 57 Primary -4.67 -13.44 -0.43 31.88 1.09 1259 28 57 0 FALSE 0.76
non-small cell lung cancer KRAS_G12A EPHB1 25 59 Metastasis 0.06 -1.31 1.14 1422.79 1.00 1302 24 58 1 FALSE 0.04
non-small cell lung cancer KRAS_G12A EPHB1 64 99 Primary 0.20 -0.99 1.11 1316.34 1.00 2150 60 95 4 FALSE 0.15
colorectal cancer KRAS_G12A EPHB1 50 82 Tumor Type:overall -4.55 -13.20 -0.32 34.93 1.08 2090 50 82 0 FALSE 0.75
non-small cell lung cancer KRAS_G12A EPHB1 89 158 Tumor Type:overall 0.14 -1.26 1.33 1415.02 1.00 3452 84 153 5 FALSE 0.08
colorectal cancer KRAS_G12A IRS2 22 11 Metastasis -1.76 -6.54 1.21 1331.38 1.00 846 22 11 0 FALSE 0.43
colorectal cancer KRAS_G12A IRS2 28 76 Primary -1.22 -4.04 0.62 1414.11 1.00 1246 27 75 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A IRS2 25 36 Metastasis -1.00 -3.81 1.05 1191.98 1.00 1324 24 35 1 FALSE 0.38
non-small cell lung cancer KRAS_G12A IRS2 63 48 Primary -1.50 -4.91 0.54 1263.26 1.00 2188 63 48 0 FALSE 0.49
colorectal cancer KRAS_G12A IRS2 50 87 Tumor Type:overall -1.43 -4.69 1.41 1374.49 1.00 2092 49 86 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A IRS2 88 84 Tumor Type:overall -1.25 -4.19 0.86 1143.00 1.00 3512 87 83 1 FALSE 0.47
colorectal cancer KRAS_G12A FANCA 22 12 Metastasis -4.64 -12.58 0.26 994.19 1.00 846 22 12 0 TRUE 0.80
colorectal cancer KRAS_G12A FANCA 28 53 Primary -4.70 -12.49 -0.20 998.44 1.00 1264 28 53 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A FANCA 25 34 Metastasis -4.85 -11.09 -0.35 890.07 1.01 1324 25 34 0 TRUE 1.03
non-small cell lung cancer KRAS_G12A FANCA 63 35 Primary -4.79 -11.34 -0.36 926.84 1.01 2202 63 35 0 TRUE 1.03
colorectal cancer KRAS_G12A FANCA 50 65 Tumor Type:overall -4.51 -12.16 0.16 927.39 1.00 2110 50 65 0 TRUE 0.82
non-small cell lung cancer KRAS_G12A FANCA 88 69 Tumor Type:overall -4.74 -10.93 -0.40 929.82 1.01 3526 88 69 0 TRUE 1.04
non-small cell lung cancer KRAS_G12A IL7R 25 35 Metastasis -0.06 -1.99 1.15 7.32 1.14 1323 24 34 1 FALSE 0.03
non-small cell lung cancer KRAS_G12A IL7R 63 56 Primary -0.14 -1.99 0.81 4.77 1.21 2189 62 55 1 FALSE 0.07
non-small cell lung cancer KRAS_G12A IL7R 88 91 Tumor Type:overall -0.10 -2.06 1.06 7.51 1.14 3512 86 89 2 FALSE 0.04
colorectal cancer KRAS_G12A ERBB3 22 39 Metastasis -0.54 -2.40 0.95 1126.07 1.00 821 21 38 1 TRUE 0.28
colorectal cancer KRAS_G12A ERBB3 28 83 Primary -0.62 -2.54 0.75 1063.76 1.00 1242 27 82 1 TRUE 0.33
colorectal cancer KRAS_G12A ERBB3 50 122 Tumor Type:overall -0.58 -2.62 0.95 1249.63 1.00 2063 48 120 2 TRUE 0.28
colorectal cancer KRAS_G12A SMAD4 23 149 Metastasis -0.24 -1.35 0.58 459.82 1.00 793 20 146 3 TRUE 0.22
colorectal cancer KRAS_G12A SMAD4 32 211 Primary -0.23 -1.35 0.52 353.25 1.01 1282 28 207 4 TRUE 0.22
non-small cell lung cancer KRAS_G12A SMAD4 25 49 Metastasis -0.63 -2.62 1.02 97.03 1.02 1360 24 48 1 TRUE 0.29
non-small cell lung cancer KRAS_G12A SMAD4 66 67 Primary -0.75 -2.74 0.75 90.34 1.02 2243 65 66 1 TRUE 0.38
colorectal cancer KRAS_G12A SMAD4 55 360 Tumor Type:overall -0.25 -1.38 0.61 404.37 1.00 2075 48 353 7 TRUE 0.21
non-small cell lung cancer KRAS_G12A SMAD4 91 116 Tumor Type:overall -0.67 -2.71 1.00 100.89 1.02 3603 89 114 2 TRUE 0.31
colorectal cancer KRAS_G12A ATM 25 71 Metastasis 0.68 -0.57 1.81 1293.27 1.00 876 20 66 5 TRUE 0.59
colorectal cancer KRAS_G12A ATM 32 160 Primary -0.59 -2.67 0.62 1140.29 1.00 1347 31 159 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A ATM 28 122 Metastasis 1.22 0.45 1.93 88.65 1.04 1303 20 114 8 TRUE 2.85
non-small cell lung cancer KRAS_G12A ATM 67 166 Primary 0.97 0.18 1.53 24.10 1.12 2168 58 157 9 TRUE 2.00
colorectal cancer KRAS_G12A ATM 57 231 Tumor Type:overall 0.00 -1.95 1.49 1380.95 1.00 2223 51 225 6 TRUE 0.00
non-small cell lung cancer KRAS_G12A ATM 95 288 Tumor Type:overall 1.08 0.12 1.96 97.47 1.04 3471 78 271 17 TRUE 1.54
colorectal cancer KRAS_G12A RB1 32 58 Primary -5.21 -13.95 -0.05 716.43 1.00 1421 32 58 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A RB1 25 96 Metastasis -1.55 -4.53 0.14 1249.93 1.00 1314 25 96 0 TRUE 0.68
non-small cell lung cancer KRAS_G12A RB1 66 127 Primary -1.14 -2.94 0.17 1203.12 1.00 2184 64 125 2 TRUE 0.81
colorectal cancer KRAS_G12A RB1 32 58 Tumor Type:overall -3.93 -10.95 2.88 431.77 1.01 1421 32 58 0 TRUE 0.57
non-small cell lung cancer KRAS_G12A RB1 91 223 Tumor Type:overall -1.34 -3.62 0.29 1411.62 1.00 3498 89 221 2 TRUE 0.72
colorectal cancer KRAS_G12A KMT2D 22 82 Metastasis -0.98 -2.69 0.41 1524.50 1.00 800 21 81 1 FALSE 0.65
colorectal cancer KRAS_G12A KMT2D 29 306 Primary -0.96 -2.27 0.12 1605.03 1.00 1136 26 303 3 FALSE 0.94
non-small cell lung cancer KRAS_G12A KMT2D 26 125 Metastasis -0.41 -1.46 0.52 671.29 1.01 1253 24 123 2 FALSE 0.36
non-small cell lung cancer KRAS_G12A KMT2D 63 203 Primary -0.42 -1.32 0.41 472.47 1.01 2063 59 199 4 FALSE 0.43
colorectal cancer KRAS_G12A KMT2D 51 388 Tumor Type:overall -0.97 -2.86 0.64 1430.03 1.00 1936 47 384 4 FALSE 0.54
non-small cell lung cancer KRAS_G12A KMT2D 89 328 Tumor Type:overall -0.41 -1.47 0.56 445.43 1.01 3316 83 322 6 FALSE 0.36
colorectal cancer KRAS_G12A TSC2 22 25 Metastasis 0.26 -1.58 1.64 1464.45 1.00 836 21 24 1 TRUE 0.12
colorectal cancer KRAS_G12A TSC2 29 90 Primary 0.35 -0.96 1.44 1273.34 1.00 1241 26 87 3 TRUE 0.26
non-small cell lung cancer KRAS_G12A TSC2 25 28 Metastasis 0.18 -2.96 1.75 1399.52 1.00 1330 25 28 0 TRUE 0.05
non-small cell lung cancer KRAS_G12A TSC2 64 44 Primary 0.91 -0.33 1.92 1093.05 1.00 2197 60 40 4 TRUE 0.92
colorectal cancer KRAS_G12A TSC2 51 115 Tumor Type:overall 0.30 -1.45 1.85 1495.63 1.00 2077 47 111 4 TRUE 0.14
non-small cell lung cancer KRAS_G12A TSC2 89 72 Tumor Type:overall 0.53 -1.70 1.99 1406.57 1.00 3527 85 68 4 TRUE 0.24
colorectal cancer KRAS_G12A APC 33 1010 Metastasis 0.22 -0.41 0.91 1514.82 1.00 280 6 983 27 TRUE 0.27
colorectal cancer KRAS_G12A APC 40 1528 Primary 0.10 -0.50 0.74 1494.62 1.00 530 10 1498 30 TRUE 0.12
non-small cell lung cancer KRAS_G12A APC 25 65 Metastasis 0.26 -0.72 1.59 9.70 1.20 1347 22 62 3 TRUE 0.15
non-small cell lung cancer KRAS_G12A APC 66 92 Primary -0.11 -1.14 0.97 25.06 1.10 2223 64 90 2 TRUE 0.07
colorectal cancer KRAS_G12A APC 73 2538 Tumor Type:overall 0.16 -0.62 0.98 1426.38 1.00 810 16 2481 57 TRUE 0.14
non-small cell lung cancer KRAS_G12A APC 91 157 Tumor Type:overall 0.09 -1.02 1.63 21.13 1.11 3570 86 152 5 TRUE 0.04
colorectal cancer KRAS_G12A ERBB2 23 32 Metastasis -4.74 -11.49 -0.48 190.68 1.02 903 23 32 0 TRUE 0.99
colorectal cancer KRAS_G12A ERBB2 32 72 Primary -4.76 -11.51 -0.61 171.37 1.02 1397 32 72 0 TRUE 0.99
non-small cell lung cancer KRAS_G12A ERBB2 25 46 Metastasis -4.65 -11.87 -0.71 273.95 1.00 1362 25 46 0 TRUE 0.95
non-small cell lung cancer KRAS_G12A ERBB2 66 83 Primary -4.70 -11.85 -0.75 232.71 1.01 2227 66 83 0 TRUE 0.97
colorectal cancer KRAS_G12A ERBB2 55 104 Tumor Type:overall -4.70 -11.48 -0.49 147.79 1.03 2300 55 104 0 TRUE 1.00
non-small cell lung cancer KRAS_G12A ERBB2 91 129 Tumor Type:overall -4.60 -11.47 -0.50 273.06 1.00 3589 91 129 0 TRUE 0.97
colorectal cancer KRAS_G12A JAK1 22 12 Metastasis 1.21 -1.11 2.97 1338.19 1.00 846 20 10 2 TRUE 0.60
colorectal cancer KRAS_G12A JAK1 28 63 Primary -1.73 -8.29 0.80 1351.06 1.00 1264 28 63 0 TRUE 0.35
non-small cell lung cancer KRAS_G12A JAK1 25 20 Metastasis 0.26 -1.64 1.84 1070.25 1.00 1338 24 19 1 TRUE 0.11
non-small cell lung cancer KRAS_G12A JAK1 63 32 Primary 0.14 -1.80 1.56 1032.19 1.00 2207 62 31 1 TRUE 0.06
colorectal cancer KRAS_G12A JAK1 50 75 Tumor Type:overall -0.18 -4.43 2.72 1326.53 1.00 2110 48 73 2 TRUE 0.04
non-small cell lung cancer KRAS_G12A JAK1 88 52 Tumor Type:overall 0.21 -1.71 1.74 1006.79 1.01 3545 86 50 2 TRUE 0.09
colorectal cancer KRAS_G12A ARID2 22 31 Metastasis 0.02 -1.66 1.36 1070.71 1.00 831 21 30 1 FALSE 0.01
colorectal cancer KRAS_G12A ARID2 28 79 Primary 0.04 -1.50 1.28 882.48 1.00 1245 26 77 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A ARID2 25 74 Metastasis 0.26 -0.99 1.36 1382.43 1.00 1294 22 71 3 FALSE 0.18
non-small cell lung cancer KRAS_G12A ARID2 63 108 Primary -0.13 -1.36 0.89 1388.96 1.00 2136 61 106 2 FALSE 0.09
colorectal cancer KRAS_G12A ARID2 50 110 Tumor Type:overall 0.05 -1.66 1.58 1053.51 1.00 2076 47 107 3 FALSE 0.02
non-small cell lung cancer KRAS_G12A ARID2 88 182 Tumor Type:overall 0.08 -1.30 1.38 1223.89 1.00 3430 83 177 5 FALSE 0.04
non-small cell lung cancer KRAS_G12A SOX17 25 26 Metastasis -0.41 -3.29 1.30 39.58 1.04 1332 24 25 1 FALSE 0.14
non-small cell lung cancer KRAS_G12A SOX17 63 35 Primary -0.84 -4.17 0.69 27.28 1.06 2202 63 35 0 FALSE 0.25
non-small cell lung cancer KRAS_G12A SOX17 88 61 Tumor Type:overall -0.62 -3.61 1.07 29.40 1.06 3534 87 60 1 FALSE 0.21
colorectal cancer KRAS_G12A MTOR 22 41 Metastasis -1.89 -5.17 0.12 1044.42 1.00 819 22 41 0 TRUE 0.77
colorectal cancer KRAS_G12A MTOR 28 99 Primary -1.57 -3.99 0.19 1372.23 1.00 1232 27 98 1 TRUE 0.82
non-small cell lung cancer KRAS_G12A MTOR 25 39 Metastasis -0.50 -2.54 1.03 889.69 1.01 1320 24 38 1 TRUE 0.23
non-small cell lung cancer KRAS_G12A MTOR 63 76 Primary -0.66 -2.70 0.73 829.46 1.00 2162 62 75 1 TRUE 0.35
colorectal cancer KRAS_G12A MTOR 50 140 Tumor Type:overall -1.71 -4.91 0.30 1404.93 1.00 2051 49 139 1 TRUE 0.76
non-small cell lung cancer KRAS_G12A MTOR 88 115 Tumor Type:overall -0.57 -2.70 0.94 892.54 1.01 3482 86 113 2 TRUE 0.26
non-small cell lung cancer KRAS_G12A RFWD2 25 22 Metastasis 0.25 -1.80 1.74 884.20 1.00 1336 24 21 1 FALSE 0.11
non-small cell lung cancer KRAS_G12A RFWD2 63 35 Primary 0.12 -1.99 1.56 772.36 1.00 2201 62 34 1 FALSE 0.05
non-small cell lung cancer KRAS_G12A RFWD2 88 57 Tumor Type:overall 0.18 -1.95 1.75 915.24 1.00 3537 86 55 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A IRS1 25 30 Metastasis -0.85 -3.95 1.26 1035.24 1.00 1328 24 29 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A IRS1 63 43 Primary -1.36 -5.01 0.72 985.28 1.00 2195 63 43 0 FALSE 0.44
non-small cell lung cancer KRAS_G12A IRS1 88 73 Tumor Type:overall -1.09 -4.14 1.02 999.99 1.00 3523 87 72 1 FALSE 0.38
colorectal cancer KRAS_G12A NOTCH1 24 39 Metastasis 0.61 -1.09 2.02 1555.72 1.00 899 21 36 3 TRUE 0.35
colorectal cancer KRAS_G12A NOTCH1 32 133 Primary -1.98 -6.69 0.29 1406.54 1.00 1368 32 133 0 TRUE 0.55
non-small cell lung cancer KRAS_G12A NOTCH1 25 52 Metastasis 0.47 -0.75 1.56 1355.56 1.00 1360 23 50 2 TRUE 0.38
non-small cell lung cancer KRAS_G12A NOTCH1 66 78 Primary 0.37 -0.76 1.28 1279.30 1.00 2237 63 75 3 TRUE 0.32
colorectal cancer KRAS_G12A NOTCH1 56 172 Tumor Type:overall -0.59 -4.26 1.85 1514.05 1.00 2267 53 169 3 TRUE 0.17
non-small cell lung cancer KRAS_G12A NOTCH1 91 130 Tumor Type:overall 0.43 -0.88 1.59 1289.26 1.00 3597 86 125 5 TRUE 0.30
colorectal cancer KRAS_G12A NTRK1 22 16 Metastasis 1.63 0.28 2.94 1249.90 1.00 843 19 13 3 TRUE 1.80
colorectal cancer KRAS_G12A NTRK1 28 48 Primary 1.06 -0.48 2.19 1116.90 1.00 1270 26 46 2 TRUE 0.97
non-small cell lung cancer KRAS_G12A NTRK1 25 44 Metastasis 0.38 -1.38 1.60 1345.92 1.00 1315 24 43 1 TRUE 0.21
non-small cell lung cancer KRAS_G12A NTRK1 63 44 Primary 0.63 -0.73 1.72 1277.05 1.00 2195 60 41 3 TRUE 0.50
colorectal cancer KRAS_G12A NTRK1 50 64 Tumor Type:overall 1.32 -0.45 2.89 1367.79 1.00 2113 45 59 5 TRUE 0.96
non-small cell lung cancer KRAS_G12A NTRK1 88 88 Tumor Type:overall 0.50 -1.13 1.86 1316.03 1.00 3510 84 84 4 TRUE 0.28
non-small cell lung cancer KRAS_G12A INPP4A 25 21 Metastasis -0.98 -4.38 1.18 399.10 1.01 1337 25 21 0 FALSE 0.30
non-small cell lung cancer KRAS_G12A INPP4A 63 32 Primary -0.77 -4.17 1.17 258.69 1.02 2204 62 31 1 FALSE 0.25
non-small cell lung cancer KRAS_G12A INPP4A 88 53 Tumor Type:overall -0.86 -4.26 1.27 321.76 1.01 3541 87 52 1 FALSE 0.28
colorectal cancer KRAS_G12A SETD2 22 29 Metastasis -1.08 -4.57 0.86 1535.98 1.00 832 22 29 0 FALSE 0.31
colorectal cancer KRAS_G12A SETD2 28 84 Primary -0.41 -2.39 1.09 1352.97 1.00 1247 26 82 2 FALSE 0.19
non-small cell lung cancer KRAS_G12A SETD2 26 93 Metastasis 0.15 -0.93 1.13 939.24 1.00 1283 23 90 3 FALSE 0.12
non-small cell lung cancer KRAS_G12A SETD2 63 132 Primary -0.03 -1.11 0.82 953.73 1.01 2123 60 129 3 FALSE 0.03
colorectal cancer KRAS_G12A SETD2 50 113 Tumor Type:overall -0.71 -3.42 1.22 1460.33 1.00 2079 48 111 2 FALSE 0.26
non-small cell lung cancer KRAS_G12A SETD2 89 225 Tumor Type:overall 0.06 -1.13 1.13 1148.62 1.00 3406 83 219 6 FALSE 0.04
colorectal cancer KRAS_G12A PBRM1 22 15 Metastasis -1.71 -6.07 1.06 1556.22 1.00 843 22 15 0 TRUE 0.43
colorectal cancer KRAS_G12A PBRM1 28 79 Primary -1.22 -4.07 0.77 1395.11 1.00 1246 27 78 1 TRUE 0.48
non-small cell lung cancer KRAS_G12A PBRM1 25 54 Metastasis -0.69 -3.90 0.99 1231.95 1.00 1311 25 54 0 TRUE 0.22
non-small cell lung cancer KRAS_G12A PBRM1 63 60 Primary 0.13 -1.28 1.30 1181.23 1.00 2185 60 57 3 TRUE 0.08
colorectal cancer KRAS_G12A PBRM1 50 94 Tumor Type:overall -1.41 -4.84 1.26 1421.35 1.00 2089 49 93 1 TRUE 0.42
non-small cell lung cancer KRAS_G12A PBRM1 88 114 Tumor Type:overall -0.24 -2.47 1.40 1334.73 1.00 3496 85 111 3 TRUE 0.09
colorectal cancer KRAS_G12A EPHA3 22 34 Metastasis 0.00 -1.69 1.30 845.50 1.01 824 21 33 1 FALSE 0.00
colorectal cancer KRAS_G12A EPHA3 28 79 Primary 0.00 -1.52 1.18 781.89 1.00 1246 26 77 2 FALSE 0.00
non-small cell lung cancer KRAS_G12A EPHA3 26 83 Metastasis 0.50 -0.47 1.52 1016.57 1.00 1282 22 79 4 FALSE 0.47
non-small cell lung cancer KRAS_G12A EPHA3 63 159 Primary 0.15 -0.82 0.91 1232.93 1.00 2096 59 155 4 FALSE 0.13
colorectal cancer KRAS_G12A EPHA3 50 113 Tumor Type:overall 0.00 -1.67 1.41 786.07 1.00 2070 47 110 3 FALSE 0.00
non-small cell lung cancer KRAS_G12A EPHA3 89 242 Tumor Type:overall 0.32 -0.69 1.43 1520.61 1.00 3378 81 234 8 FALSE 0.22
colorectal cancer KRAS_G12A KIT 23 17 Metastasis -4.11 -11.40 0.39 398.49 1.00 914 23 17 0 TRUE 0.75
colorectal cancer KRAS_G12A KIT 32 37 Primary -4.17 -11.04 0.17 399.76 1.01 1432 32 37 0 TRUE 0.77
non-small cell lung cancer KRAS_G12A KIT 25 30 Metastasis -4.96 -12.25 -0.43 401.74 1.02 1376 25 30 0 TRUE 0.94
non-small cell lung cancer KRAS_G12A KIT 66 51 Primary -4.97 -12.13 -0.56 381.26 1.02 2259 66 51 0 TRUE 0.96
colorectal cancer KRAS_G12A KIT 55 54 Tumor Type:overall -4.09 -11.00 0.28 391.63 1.00 2346 55 54 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A KIT 91 81 Tumor Type:overall -4.93 -12.23 -0.50 389.31 1.02 3635 91 81 0 TRUE 0.95
colorectal cancer KRAS_G12A KDR 23 15 Metastasis -1.29 -4.86 1.00 1388.77 1.00 916 23 15 0 TRUE 0.38
colorectal cancer KRAS_G12A KDR 32 60 Primary -0.91 -3.72 0.91 1556.36 1.00 1417 31 59 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A KDR 25 51 Metastasis 0.48 -0.76 1.61 1298.82 1.00 1359 23 49 2 TRUE 0.38
non-small cell lung cancer KRAS_G12A KDR 66 103 Primary 0.38 -0.69 1.25 1390.11 1.00 2214 62 99 4 TRUE 0.36
colorectal cancer KRAS_G12A KDR 55 75 Tumor Type:overall -1.05 -4.30 1.31 1593.35 1.00 2333 54 74 1 TRUE 0.34
non-small cell lung cancer KRAS_G12A KDR 91 154 Tumor Type:overall 0.43 -0.92 1.50 1484.94 1.00 3573 85 148 6 TRUE 0.32
colorectal cancer KRAS_G12A RICTOR 22 11 Metastasis -1.51 -6.03 1.34 1533.52 1.00 847 22 11 0 FALSE 0.37
colorectal cancer KRAS_G12A RICTOR 28 59 Primary -0.95 -3.90 0.98 1486.25 1.00 1264 27 58 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A RICTOR 25 24 Metastasis -1.18 -4.81 0.98 1470.22 1.00 1334 25 24 0 FALSE 0.38
non-small cell lung cancer KRAS_G12A RICTOR 63 40 Primary -0.93 -3.66 0.90 1136.83 1.00 2198 62 39 1 FALSE 0.36
colorectal cancer KRAS_G12A RICTOR 50 70 Tumor Type:overall -1.16 -4.76 1.48 1538.32 1.00 2111 49 69 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A RICTOR 88 64 Tumor Type:overall -1.04 -4.11 1.05 1284.21 1.00 3532 87 63 1 FALSE 0.36
colorectal cancer KRAS_G12A RAD50 22 18 Metastasis -0.62 -3.45 1.52 1095.15 1.00 842 21 17 1 FALSE 0.20
colorectal cancer KRAS_G12A RAD50 28 42 Primary -1.12 -4.44 0.94 1288.51 1.00 1275 28 42 0 FALSE 0.37
colorectal cancer KRAS_G12A RAD50 50 60 Tumor Type:overall -0.85 -3.70 1.25 1181.65 1.00 2117 49 59 1 FALSE 0.29
colorectal cancer KRAS_G12A CSF1R 24 18 Metastasis 0.59 -1.32 2.14 1178.43 1.01 918 22 16 2 TRUE 0.30
colorectal cancer KRAS_G12A CSF1R 32 38 Primary -0.25 -3.89 1.42 939.05 1.00 1430 32 38 0 TRUE 0.07
non-small cell lung cancer KRAS_G12A CSF1R 25 31 Metastasis 0.62 -0.86 2.10 347.34 1.01 1379 23 29 2 TRUE 0.38
non-small cell lung cancer KRAS_G12A CSF1R 66 38 Primary 0.24 -1.46 1.47 1338.62 1.00 2271 65 37 1 TRUE 0.13
colorectal cancer KRAS_G12A CSF1R 56 56 Tumor Type:overall 0.21 -2.15 1.97 1186.92 1.00 2348 54 54 2 TRUE 0.07
non-small cell lung cancer KRAS_G12A CSF1R 91 69 Tumor Type:overall 0.43 -1.31 2.01 1102.95 1.01 3650 88 66 3 TRUE 0.22
non-small cell lung cancer KRAS_G12A PARK2 25 31 Metastasis -1.21 -4.72 0.92 1007.54 1.00 1326 25 31 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A PARK2 63 34 Primary -0.86 -3.58 1.02 778.05 1.00 2202 62 33 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A PARK2 88 65 Tumor Type:overall -1.03 -4.01 1.08 865.56 1.00 3528 87 64 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A NTRK2 25 22 Metastasis 0.49 -1.09 1.79 1405.66 1.00 1338 24 21 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A NTRK2 63 45 Primary 0.43 -1.03 1.61 1345.37 1.00 2195 61 43 2 FALSE 0.28
non-small cell lung cancer KRAS_G12A NTRK2 88 67 Tumor Type:overall 0.45 -1.26 1.85 1404.26 1.00 3533 85 64 3 FALSE 0.24
colorectal cancer KRAS_G12A PTCH1 22 38 Metastasis -1.35 -4.71 0.85 863.47 1.00 828 21 37 1 TRUE 0.49
colorectal cancer KRAS_G12A PTCH1 28 107 Primary -2.08 -5.87 -0.03 999.19 1.00 1230 28 107 0 TRUE 0.73
non-small cell lung cancer KRAS_G12A PTCH1 25 27 Metastasis -4.59 -10.83 -0.12 1015.62 1.00 1331 25 27 0 TRUE 1.02
non-small cell lung cancer KRAS_G12A PTCH1 63 35 Primary -4.57 -10.72 -0.22 1053.67 1.00 2200 63 35 0 TRUE 1.02
colorectal cancer KRAS_G12A PTCH1 50 145 Tumor Type:overall -1.70 -5.13 0.53 1029.93 1.00 2058 49 144 1 TRUE 0.63
non-small cell lung cancer KRAS_G12A PTCH1 88 62 Tumor Type:overall -4.50 -10.76 -0.15 1039.19 1.00 3531 88 62 0 TRUE 1.03
non-small cell lung cancer KRAS_G12A TET1 26 58 Metastasis 0.64 -0.52 1.74 1437.57 1.00 1308 23 55 3 FALSE 0.55
non-small cell lung cancer KRAS_G12A TET1 63 68 Primary 0.30 -0.95 1.31 1438.47 1.00 2174 61 66 2 FALSE 0.22
non-small cell lung cancer KRAS_G12A TET1 89 126 Tumor Type:overall 0.45 -1.01 1.69 1519.20 1.00 3482 84 121 5 FALSE 0.27
colorectal cancer KRAS_G12A FGFR2 23 19 Metastasis -0.53 -3.19 1.51 1235.83 1.00 913 22 18 1 TRUE 0.18
colorectal cancer KRAS_G12A FGFR2 32 34 Primary -0.87 -4.10 1.11 1394.92 1.00 1435 32 34 0 TRUE 0.29
colorectal cancer KRAS_G12A FGFR2 55 53 Tumor Type:overall -0.69 -3.84 1.32 1434.07 1.00 2348 54 52 1 TRUE 0.23
colorectal cancer KRAS_G12A TBX3 22 18 Metastasis -1.46 -5.08 0.89 1297.47 1.00 839 22 18 0 FALSE 0.45
colorectal cancer KRAS_G12A TBX3 28 62 Primary -1.09 -4.02 0.88 1016.14 1.00 1264 27 61 1 FALSE 0.42
non-small cell lung cancer KRAS_G12A TBX3 25 60 Metastasis -0.05 -1.61 1.36 1020.83 1.00 1305 23 58 2 FALSE 0.02
non-small cell lung cancer KRAS_G12A TBX3 63 77 Primary -0.41 -2.15 0.86 1118.20 1.00 2162 62 76 1 FALSE 0.24
colorectal cancer KRAS_G12A TBX3 50 80 Tumor Type:overall -1.24 -4.38 1.07 1168.43 1.00 2103 49 79 1 FALSE 0.41
non-small cell lung cancer KRAS_G12A TBX3 88 137 Tumor Type:overall -0.24 -2.08 1.22 1089.70 1.00 3467 85 134 3 FALSE 0.12
colorectal cancer KRAS_G12A HNF1A 32 43 Primary -4.85 -14.96 0.49 598.62 1.01 1423 32 43 0 TRUE 0.62
colorectal cancer KRAS_G12A HNF1A 32 43 Tumor Type:overall -3.44 -10.77 3.10 556.09 1.00 1423 32 43 0 TRUE 0.46
colorectal cancer KRAS_G12A DICER1 22 27 Metastasis -4.53 -10.97 -0.24 157.27 1.01 834 22 27 0 TRUE 0.86
colorectal cancer KRAS_G12A DICER1 28 49 Primary -4.53 -11.16 -0.28 155.23 1.01 1273 28 49 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A DICER1 25 33 Metastasis -4.84 -11.48 -0.43 1077.59 1.00 1327 25 33 0 TRUE 1.02
non-small cell lung cancer KRAS_G12A DICER1 63 57 Primary -4.85 -11.60 -0.64 1112.21 1.00 2181 63 57 0 TRUE 1.03
colorectal cancer KRAS_G12A DICER1 50 76 Tumor Type:overall -4.48 -11.11 -0.26 152.19 1.01 2107 50 76 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A DICER1 88 90 Tumor Type:overall -4.80 -11.46 -0.53 1100.09 1.00 3508 88 90 0 TRUE 1.04
colorectal cancer KRAS_G12A SMAD3 23 38 Metastasis 0.62 -0.56 1.68 1161.68 1.00 822 21 36 2 TRUE 0.56
colorectal cancer KRAS_G12A SMAD3 30 69 Primary 0.63 -0.42 1.58 1335.88 1.00 1256 27 66 3 TRUE 0.65
colorectal cancer KRAS_G12A SMAD3 53 107 Tumor Type:overall 0.62 -0.60 1.67 1345.18 1.00 2078 48 102 5 TRUE 0.53
colorectal cancer KRAS_G12A NTRK3 22 15 Metastasis -1.28 -4.99 1.11 1043.02 1.00 843 22 15 0 FALSE 0.37
colorectal cancer KRAS_G12A NTRK3 28 55 Primary -0.92 -3.71 0.84 961.36 1.00 1265 27 54 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A NTRK3 25 81 Metastasis 0.25 -0.82 1.25 1272.72 1.00 1284 23 79 2 FALSE 0.20
non-small cell lung cancer KRAS_G12A NTRK3 65 126 Primary 0.30 -0.64 1.08 1458.61 1.00 2132 60 121 5 FALSE 0.30
colorectal cancer KRAS_G12A NTRK3 50 70 Tumor Type:overall -1.06 -4.03 1.12 1140.21 1.00 2108 49 69 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A NTRK3 90 207 Tumor Type:overall 0.28 -0.86 1.34 1470.22 1.00 3416 83 200 7 FALSE 0.21
colorectal cancer KRAS_G12A AXIN1 22 17 Metastasis -4.54 -11.72 0.02 771.35 1.00 842 22 17 0 FALSE 0.83
colorectal cancer KRAS_G12A AXIN1 28 54 Primary -4.59 -11.63 -0.04 851.44 1.00 1265 28 54 0 FALSE 0.86
colorectal cancer KRAS_G12A AXIN1 50 71 Tumor Type:overall -4.44 -11.14 0.14 805.33 1.00 2107 50 71 0 FALSE 0.84
colorectal cancer KRAS_G12A GRIN2A 23 41 Metastasis -0.31 -2.34 1.34 1362.50 1.00 817 21 39 2 FALSE 0.13
colorectal cancer KRAS_G12A GRIN2A 28 95 Primary -1.35 -4.93 0.51 1204.59 1.00 1231 28 95 0 FALSE 0.47
non-small cell lung cancer KRAS_G12A GRIN2A 25 80 Metastasis -2.21 -5.05 -0.23 852.05 1.00 1281 25 80 0 FALSE 1.00
non-small cell lung cancer KRAS_G12A GRIN2A 63 113 Primary -2.02 -4.74 -0.25 872.34 1.00 2131 62 112 1 FALSE 1.15
colorectal cancer KRAS_G12A GRIN2A 51 136 Tumor Type:overall -0.82 -3.20 1.12 1306.42 1.00 2048 49 134 2 FALSE 0.32
non-small cell lung cancer KRAS_G12A GRIN2A 88 193 Tumor Type:overall -2.08 -4.91 -0.13 838.39 1.01 3412 87 192 1 FALSE 1.12
colorectal cancer KRAS_G12A PALB2 28 47 Primary -0.42 -3.25 1.44 735.12 1.00 1271 27 46 1 TRUE 0.14
non-small cell lung cancer KRAS_G12A PALB2 25 28 Metastasis -0.56 -3.71 1.40 279.70 1.01 1333 24 27 1 TRUE 0.18
non-small cell lung cancer KRAS_G12A PALB2 63 32 Primary -1.03 -4.58 1.12 188.47 1.01 2203 63 32 0 TRUE 0.31
colorectal cancer KRAS_G12A PALB2 28 47 Tumor Type:overall -0.33 -5.30 3.88 1280.04 1.00 1271 27 46 1 TRUE 0.06
non-small cell lung cancer KRAS_G12A PALB2 88 60 Tumor Type:overall -0.78 -4.02 1.31 225.27 1.01 3536 87 59 1 TRUE 0.24
colorectal cancer KRAS_G12A CTCF 22 24 Metastasis -4.82 -12.24 -0.13 1365.37 1.00 836 22 24 0 FALSE 0.85
colorectal cancer KRAS_G12A CTCF 28 66 Primary -4.83 -12.34 -0.32 1382.87 1.00 1256 28 66 0 FALSE 0.88
colorectal cancer KRAS_G12A CTCF 50 90 Tumor Type:overall -4.70 -12.01 -0.11 1394.90 1.00 2092 50 90 0 FALSE 0.87
colorectal cancer KRAS_G12A CDH1 23 13 Metastasis -0.29 -3.06 2.07 479.47 1.00 921 22 12 1 TRUE 0.08
colorectal cancer KRAS_G12A CDH1 32 41 Primary -1.12 -4.64 1.04 444.73 1.00 1430 32 41 0 TRUE 0.34
colorectal cancer KRAS_G12A CDH1 55 54 Tumor Type:overall -0.69 -3.68 1.63 515.97 1.00 2351 54 53 1 TRUE 0.20
colorectal cancer KRAS_G12A CDK12 22 21 Metastasis -0.82 -4.17 1.16 1196.50 1.00 840 22 21 0 FALSE 0.24
colorectal cancer KRAS_G12A CDK12 29 69 Primary -0.20 -2.03 1.26 1439.04 1.00 1254 27 67 2 FALSE 0.09
non-small cell lung cancer KRAS_G12A CDK12 25 24 Metastasis -1.00 -4.24 1.09 1174.19 1.00 1333 25 24 0 FALSE 0.33
non-small cell lung cancer KRAS_G12A CDK12 63 35 Primary -0.78 -3.56 1.05 942.79 1.00 2203 62 34 1 FALSE 0.29
colorectal cancer KRAS_G12A CDK12 51 90 Tumor Type:overall -0.50 -3.18 1.46 1263.61 1.00 2094 49 88 2 FALSE 0.17
non-small cell lung cancer KRAS_G12A CDK12 88 59 Tumor Type:overall -0.88 -3.91 1.22 999.85 1.00 3536 87 58 1 FALSE 0.30
non-small cell lung cancer KRAS_G12A STK11 25 205 Metastasis 0.88 0.16 1.68 1334.25 1.00 1213 16 196 9 TRUE 1.59
non-small cell lung cancer KRAS_G12A STK11 67 338 Primary 0.52 -0.09 1.06 1157.17 1.00 1997 54 325 13 TRUE 1.15
non-small cell lung cancer KRAS_G12A STK11 92 543 Tumor Type:overall 0.68 -0.34 1.75 1546.70 1.00 3210 70 521 22 TRUE 0.63
colorectal cancer KRAS_G12A BRD4 22 22 Metastasis -0.76 -3.43 1.37 1425.94 1.00 838 21 21 1 FALSE 0.25
colorectal cancer KRAS_G12A BRD4 28 66 Primary -1.59 -5.42 0.56 1247.89 1.00 1251 28 66 0 FALSE 0.51
non-small cell lung cancer KRAS_G12A BRD4 25 27 Metastasis -4.73 -11.87 -0.06 1088.39 1.00 1332 25 27 0 FALSE 0.87
non-small cell lung cancer KRAS_G12A BRD4 63 26 Primary -4.71 -11.79 -0.07 1128.90 1.00 2209 63 26 0 FALSE 0.87
colorectal cancer KRAS_G12A BRD4 50 88 Tumor Type:overall -1.12 -4.14 1.20 1328.91 1.00 2089 49 87 1 FALSE 0.37
non-small cell lung cancer KRAS_G12A BRD4 88 53 Tumor Type:overall -4.61 -11.57 0.02 1108.14 1.00 3541 88 53 0 FALSE 0.86
colorectal cancer KRAS_G12A ASXL1 22 34 Metastasis -1.13 -4.07 0.80 118.95 1.03 824 21 33 1 TRUE 0.43
colorectal cancer KRAS_G12A ASXL1 28 75 Primary -1.56 -4.81 0.42 96.43 1.03 1247 28 75 0 TRUE 0.55
non-small cell lung cancer KRAS_G12A ASXL1 25 44 Metastasis -1.01 -4.00 1.07 1199.06 1.00 1327 24 43 1 TRUE 0.37
non-small cell lung cancer KRAS_G12A ASXL1 63 42 Primary -1.63 -5.38 0.63 1177.12 1.00 2194 63 42 0 TRUE 0.52
colorectal cancer KRAS_G12A ASXL1 50 109 Tumor Type:overall -1.33 -4.28 0.56 100.66 1.04 2071 49 108 1 TRUE 0.50
non-small cell lung cancer KRAS_G12A ASXL1 88 86 Tumor Type:overall -1.31 -4.80 0.93 1219.99 1.00 3521 87 85 1 TRUE 0.45
colorectal cancer KRAS_G12A EP300 22 38 Metastasis 0.35 -0.97 1.61 1414.38 1.00 826 20 36 2 TRUE 0.24
colorectal cancer KRAS_G12A EP300 28 87 Primary 0.19 -1.21 1.27 1419.12 1.00 1246 26 85 2 TRUE 0.12
non-small cell lung cancer KRAS_G12A EP300 25 57 Metastasis 0.32 -1.35 1.54 1106.60 1.00 1307 24 56 1 TRUE 0.18
non-small cell lung cancer KRAS_G12A EP300 63 51 Primary 0.85 -0.33 1.83 1154.47 1.00 2193 59 47 4 TRUE 0.95
colorectal cancer KRAS_G12A EP300 50 125 Tumor Type:overall 0.27 -1.26 1.65 1397.39 1.00 2072 46 121 4 TRUE 0.15
non-small cell lung cancer KRAS_G12A EP300 88 108 Tumor Type:overall 0.54 -1.21 1.94 1400.10 1.00 3500 83 103 5 TRUE 0.31
colorectal cancer KRAS_G12A ERBB4 24 50 Metastasis 0.67 -0.76 1.93 903.59 1.00 886 20 46 4 TRUE 0.49
colorectal cancer KRAS_G12A ERBB4 32 88 Primary -0.97 -5.94 0.88 961.72 1.00 1394 32 88 0 TRUE 0.23
non-small cell lung cancer KRAS_G12A ERBB4 25 88 Metastasis 0.31 -0.88 1.31 1452.84 1.00 1334 23 86 2 TRUE 0.24
non-small cell lung cancer KRAS_G12A ERBB4 68 105 Primary 0.43 -0.46 1.27 1330.72 1.00 2220 63 100 5 TRUE 0.47
colorectal cancer KRAS_G12A ERBB4 56 138 Tumor Type:overall -0.08 -3.33 2.08 1255.19 1.00 2280 52 134 4 TRUE 0.02
non-small cell lung cancer KRAS_G12A ERBB4 93 193 Tumor Type:overall 0.35 -1.03 1.46 1442.51 1.00 3554 86 186 7 TRUE 0.24
non-small cell lung cancer KRAS_G12A MDC1 25 60 Metastasis -1.06 -3.98 0.84 1500.23 1.00 1309 24 59 1 FALSE 0.40
non-small cell lung cancer KRAS_G12A MDC1 63 35 Primary -1.90 -6.17 0.51 1476.06 1.00 2200 63 35 0 FALSE 0.57
non-small cell lung cancer KRAS_G12A MDC1 88 95 Tumor Type:overall -1.43 -4.83 1.19 1452.86 1.00 3509 87 94 1 FALSE 0.45
non-small cell lung cancer KRAS_G12A RECQL4 25 23 Metastasis -4.52 -11.94 0.02 1362.22 1.00 1334 25 23 0 TRUE 0.87
non-small cell lung cancer KRAS_G12A RECQL4 63 41 Primary -4.56 -11.62 -0.30 1389.70 1.00 2197 63 41 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A RECQL4 88 64 Tumor Type:overall -4.45 -11.44 -0.10 1415.80 1.00 3531 88 64 0 TRUE 0.88
colorectal cancer KRAS_G12A MED12 22 28 Metastasis -5.10 -11.54 -0.56 302.95 1.01 834 22 28 0 TRUE 1.04
colorectal cancer KRAS_G12A MED12 28 80 Primary -5.11 -11.65 -0.75 318.15 1.01 1242 28 80 0 TRUE 1.07
non-small cell lung cancer KRAS_G12A MED12 25 57 Metastasis 0.14 -1.28 1.21 1374.13 1.00 1305 24 56 1 TRUE 0.08
non-small cell lung cancer KRAS_G12A MED12 63 119 Primary 0.31 -0.67 1.19 1453.35 1.00 2131 58 114 5 TRUE 0.30
colorectal cancer KRAS_G12A MED12 50 108 Tumor Type:overall -4.99 -11.45 -0.60 295.30 1.01 2076 50 108 0 TRUE 1.03
non-small cell lung cancer KRAS_G12A MED12 88 176 Tumor Type:overall 0.24 -1.11 1.31 1501.30 1.00 3436 82 170 6 TRUE 0.15
non-small cell lung cancer KRAS_G12A ERCC5 25 30 Metastasis -1.18 -4.25 0.78 1300.07 1.00 1328 25 30 0 TRUE 0.41
non-small cell lung cancer KRAS_G12A ERCC5 63 43 Primary -0.96 -3.59 0.74 1112.23 1.00 2198 62 42 1 TRUE 0.40
non-small cell lung cancer KRAS_G12A ERCC5 88 73 Tumor Type:overall -1.06 -3.86 0.89 1275.74 1.00 3526 87 72 1 TRUE 0.40
colorectal cancer KRAS_G12A BRCA1 22 17 Metastasis -0.59 -3.52 1.63 1466.71 1.00 840 21 16 1 TRUE 0.19
colorectal cancer KRAS_G12A BRCA1 28 62 Primary -1.64 -5.66 0.62 1319.96 1.00 1265 28 62 0 TRUE 0.45
non-small cell lung cancer KRAS_G12A BRCA1 25 41 Metastasis -0.15 -3.00 1.26 1168.26 1.00 1317 25 41 0 TRUE 0.05
non-small cell lung cancer KRAS_G12A BRCA1 64 56 Primary 0.52 -0.62 1.51 118.20 1.02 2186 60 52 4 TRUE 0.45
colorectal cancer KRAS_G12A BRCA1 50 79 Tumor Type:overall -1.07 -4.30 1.44 1435.63 1.00 2105 49 78 1 TRUE 0.34
non-small cell lung cancer KRAS_G12A BRCA1 89 97 Tumor Type:overall 0.21 -1.98 1.61 1154.87 1.00 3503 85 93 4 TRUE 0.09
colorectal cancer KRAS_G12A RBM10 22 22 Metastasis -4.32 -11.26 -0.22 52.88 1.07 834 22 22 0 FALSE 0.82
colorectal cancer KRAS_G12A RBM10 28 50 Primary -4.36 -11.59 -0.20 53.47 1.07 1269 28 50 0 FALSE 0.82
non-small cell lung cancer KRAS_G12A RBM10 25 122 Metastasis 1.01 0.29 1.78 1538.20 1.00 1247 19 116 6 FALSE 2.13
non-small cell lung cancer KRAS_G12A RBM10 63 261 Primary 0.90 0.32 1.44 1135.26 1.00 2002 49 247 14 FALSE 2.83
colorectal cancer KRAS_G12A RBM10 50 72 Tumor Type:overall -4.24 -11.42 -0.16 53.02 1.07 2103 50 72 0 FALSE 0.82
non-small cell lung cancer KRAS_G12A RBM10 88 383 Tumor Type:overall 0.94 0.05 1.85 1368.58 1.00 3249 68 363 20 FALSE 1.24
colorectal cancer KRAS_G12A TSC1 22 16 Metastasis -4.21 -11.57 -0.06 81.54 1.05 843 22 16 0 TRUE 0.76
colorectal cancer KRAS_G12A TSC1 28 51 Primary -4.23 -11.68 -0.23 81.98 1.05 1270 28 51 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A TSC1 25 25 Metastasis 1.41 0.02 2.73 1626.65 1.00 1335 22 22 3 TRUE 1.37
non-small cell lung cancer KRAS_G12A TSC1 63 32 Primary 0.69 -1.05 1.90 1327.53 1.00 2205 62 31 1 TRUE 0.44
colorectal cancer KRAS_G12A TSC1 50 67 Tumor Type:overall -4.11 -11.33 -0.03 80.77 1.05 2113 50 67 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A TSC1 88 57 Tumor Type:overall 1.04 -0.69 2.53 1410.01 1.00 3540 84 53 4 TRUE 0.69
colorectal cancer KRAS_G12A FLCN 22 18 Metastasis 0.93 -0.60 2.26 1316.46 1.00 843 20 16 2 TRUE 0.72
colorectal cancer KRAS_G12A FLCN 28 36 Primary 0.67 -0.96 1.90 1198.73 1.00 1280 27 35 1 TRUE 0.45
colorectal cancer KRAS_G12A FLCN 50 54 Tumor Type:overall 0.81 -0.90 2.25 1299.98 1.00 2123 47 51 3 TRUE 0.53
colorectal cancer KRAS_G12A NF1 23 37 Metastasis 0.06 -1.62 1.56 1304.57 1.00 826 21 35 2 TRUE 0.03
colorectal cancer KRAS_G12A NF1 28 105 Primary -0.49 -2.20 0.79 1180.90 1.00 1238 27 104 1 TRUE 0.27
non-small cell lung cancer KRAS_G12A NF1 25 125 Metastasis -1.44 -4.21 -0.13 283.94 1.02 1250 25 125 0 TRUE 0.76
non-small cell lung cancer KRAS_G12A NF1 63 190 Primary -1.00 -2.35 0.04 1393.46 1.00 2075 60 187 3 TRUE 1.07
colorectal cancer KRAS_G12A NF1 51 142 Tumor Type:overall -0.22 -2.23 1.51 1191.35 1.00 2064 48 139 3 TRUE 0.09
non-small cell lung cancer KRAS_G12A NF1 88 315 Tumor Type:overall -1.22 -3.46 0.06 1129.83 1.01 3325 85 312 3 TRUE 0.80
colorectal cancer KRAS_G12A FLT1 22 20 Metastasis -4.59 -11.45 -0.16 206.56 1.02 839 22 20 0 FALSE 0.88
colorectal cancer KRAS_G12A FLT1 28 62 Primary -4.62 -11.48 -0.26 227.71 1.02 1262 28 62 0 FALSE 0.90
non-small cell lung cancer KRAS_G12A FLT1 25 52 Metastasis -0.34 -3.81 1.15 1052.09 1.00 1310 25 52 0 FALSE 0.10
non-small cell lung cancer KRAS_G12A FLT1 64 84 Primary 0.46 -0.68 1.38 1065.48 1.00 2162 59 79 5 FALSE 0.43
colorectal cancer KRAS_G12A FLT1 50 82 Tumor Type:overall -4.49 -10.95 -0.14 226.79 1.02 2101 50 82 0 FALSE 0.89
non-small cell lung cancer KRAS_G12A FLT1 89 136 Tumor Type:overall 0.08 -2.33 1.47 1383.40 1.00 3472 84 131 5 FALSE 0.03
colorectal cancer KRAS_G12A RPTOR 22 19 Metastasis -0.74 -3.29 1.44 868.55 1.00 842 21 18 1 FALSE 0.26
colorectal cancer KRAS_G12A RPTOR 28 51 Primary -1.34 -4.97 0.71 984.18 1.00 1264 28 51 0 FALSE 0.45
non-small cell lung cancer KRAS_G12A RPTOR 25 27 Metastasis -0.54 -3.94 1.32 123.93 1.03 1332 24 26 1 FALSE 0.17
non-small cell lung cancer KRAS_G12A RPTOR 63 38 Primary -1.02 -4.56 1.07 104.22 1.04 2198 63 38 0 FALSE 0.28
colorectal cancer KRAS_G12A RPTOR 50 70 Tumor Type:overall -1.01 -3.98 1.12 1130.79 1.00 2106 49 69 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A RPTOR 88 65 Tumor Type:overall -0.79 -4.25 1.24 107.16 1.04 3530 87 64 1 FALSE 0.23
colorectal cancer KRAS_G12A RASA1 22 17 Metastasis -0.23 -3.53 1.53 1287.38 1.00 841 22 17 0 FALSE 0.06
colorectal cancer KRAS_G12A RASA1 30 56 Primary 0.56 -0.79 1.67 1463.22 1.00 1272 27 53 3 FALSE 0.39
non-small cell lung cancer KRAS_G12A RASA1 25 38 Metastasis -5.04 -12.29 -0.36 588.08 1.00 1320 25 38 0 FALSE 0.97
non-small cell lung cancer KRAS_G12A RASA1 63 60 Primary -5.05 -12.47 -0.51 565.76 1.00 2176 63 60 0 FALSE 0.99
colorectal cancer KRAS_G12A RASA1 52 73 Tumor Type:overall 0.18 -2.41 1.96 1514.16 1.00 2113 49 70 3 FALSE 0.07
non-small cell lung cancer KRAS_G12A RASA1 88 98 Tumor Type:overall -4.96 -12.06 -0.36 570.00 1.00 3496 88 98 0 FALSE 0.98
colorectal cancer KRAS_G12A EPHA5 22 43 Metastasis -0.69 -2.68 0.92 1116.86 1.00 817 21 42 1 FALSE 0.35
colorectal cancer KRAS_G12A EPHA5 28 101 Primary -0.83 -2.69 0.66 1123.74 1.00 1235 27 100 1 FALSE 0.48
non-small cell lung cancer KRAS_G12A EPHA5 25 108 Metastasis -1.11 -4.53 0.38 1131.13 1.00 1258 25 108 0 FALSE 0.39
non-small cell lung cancer KRAS_G12A EPHA5 64 152 Primary -0.18 -1.30 0.74 879.18 1.00 2102 59 147 5 FALSE 0.14
colorectal cancer KRAS_G12A EPHA5 50 144 Tumor Type:overall -0.78 -2.73 0.84 1304.70 1.00 2052 48 142 2 FALSE 0.39
non-small cell lung cancer KRAS_G12A EPHA5 89 260 Tumor Type:overall -0.62 -2.78 0.79 1397.92 1.00 3360 84 255 5 FALSE 0.29
colorectal cancer KRAS_G12A AR 22 21 Metastasis -1.85 -5.37 0.67 1425.84 1.00 835 22 21 0 TRUE 0.60
colorectal cancer KRAS_G12A AR 28 95 Primary -1.45 -4.15 0.43 1404.82 1.00 1231 27 94 1 TRUE 0.65
non-small cell lung cancer KRAS_G12A AR 25 39 Metastasis -0.87 -3.56 0.86 883.15 1.00 1321 25 39 0 TRUE 0.35
non-small cell lung cancer KRAS_G12A AR 63 71 Primary -0.54 -2.38 0.84 520.76 1.01 2172 61 69 2 TRUE 0.29
colorectal cancer KRAS_G12A AR 50 116 Tumor Type:overall -1.62 -4.67 0.84 1482.21 1.00 2066 49 115 1 TRUE 0.56
non-small cell lung cancer KRAS_G12A AR 88 110 Tumor Type:overall -0.68 -2.77 0.99 659.29 1.00 3493 86 108 2 TRUE 0.30
colorectal cancer KRAS_G12A GNAS 23 20 Metastasis 0.47 -1.77 2.39 845.43 1.00 912 21 18 2 TRUE 0.19
colorectal cancer KRAS_G12A GNAS 32 55 Primary -0.93 -5.23 1.09 1395.97 1.00 1415 32 55 0 TRUE 0.25
colorectal cancer KRAS_G12A GNAS 55 75 Tumor Type:overall -0.18 -3.26 2.07 1221.40 1.00 2327 53 73 2 TRUE 0.05
colorectal cancer KRAS_G12A ASXL2 22 15 Metastasis -4.54 -11.92 0.26 1011.09 1.00 843 22 15 0 FALSE 0.83
colorectal cancer KRAS_G12A ASXL2 28 56 Primary -4.58 -11.94 -0.10 1052.63 1.00 1275 28 56 0 FALSE 0.86
non-small cell lung cancer KRAS_G12A ASXL2 25 29 Metastasis -0.68 -3.61 1.42 1317.06 1.00 1330 24 28 1 FALSE 0.22
non-small cell lung cancer KRAS_G12A ASXL2 63 34 Primary -1.22 -4.88 0.83 1541.31 1.00 2203 63 34 0 FALSE 0.39
colorectal cancer KRAS_G12A ASXL2 50 71 Tumor Type:overall -4.47 -11.48 0.23 1117.23 1.00 2118 50 71 0 FALSE 0.85
non-small cell lung cancer KRAS_G12A ASXL2 88 63 Tumor Type:overall -0.94 -3.92 1.23 1343.13 1.00 3533 87 62 1 FALSE 0.31
colorectal cancer KRAS_G12A SF3B1 22 21 Metastasis -1.23 -5.64 0.93 167.10 1.02 844 22 21 0 TRUE 0.34
colorectal cancer KRAS_G12A SF3B1 28 49 Primary -1.00 -5.61 0.97 114.37 1.02 1272 27 48 1 TRUE 0.32
non-small cell lung cancer KRAS_G12A SF3B1 25 33 Metastasis 0.88 -0.48 1.94 1034.55 1.00 1325 24 32 1 TRUE 0.79
non-small cell lung cancer KRAS_G12A SF3B1 64 54 Primary 1.10 0.17 1.99 1104.32 1.00 2190 59 49 5 TRUE 1.78
colorectal cancer KRAS_G12A SF3B1 50 70 Tumor Type:overall -1.09 -5.59 1.09 122.50 1.02 2116 49 69 1 TRUE 0.34
non-small cell lung cancer KRAS_G12A SF3B1 89 87 Tumor Type:overall 0.99 -0.34 2.06 925.04 1.00 3515 83 81 6 TRUE 0.98
colorectal cancer KRAS_G12A MLH1 23 12 Metastasis -4.56 -12.01 0.13 900.95 1.00 918 23 12 0 TRUE 0.82
colorectal cancer KRAS_G12A MLH1 32 44 Primary -4.66 -12.22 -0.04 860.04 1.00 1430 32 44 0 TRUE 0.86
colorectal cancer KRAS_G12A MLH1 55 56 Tumor Type:overall -4.48 -11.64 0.16 897.57 1.00 2348 55 56 0 TRUE 0.84
colorectal cancer KRAS_G12A ROS1 22 33 Metastasis -4.69 -11.78 -0.27 841.25 1.00 829 22 33 0 TRUE 0.93
colorectal cancer KRAS_G12A ROS1 28 70 Primary -4.69 -11.68 -0.38 774.27 1.00 1259 28 70 0 TRUE 0.97
non-small cell lung cancer KRAS_G12A ROS1 25 35 Metastasis 1.02 -0.60 2.46 832.89 1.00 1325 22 32 3 TRUE 0.69
non-small cell lung cancer KRAS_G12A ROS1 63 76 Primary -1.57 -6.52 0.55 1276.52 1.00 2164 63 76 0 TRUE 0.40
colorectal cancer KRAS_G12A ROS1 50 103 Tumor Type:overall -4.64 -11.42 -0.24 834.50 1.00 2088 50 103 0 TRUE 0.96
non-small cell lung cancer KRAS_G12A ROS1 88 111 Tumor Type:overall -0.19 -3.33 2.22 1387.81 1.00 3489 85 108 3 TRUE 0.05
colorectal cancer KRAS_G12A PIK3R2 28 42 Primary -0.34 -3.19 1.51 1279.05 1.00 1275 27 41 1 FALSE 0.11
colorectal cancer KRAS_G12A PIK3R2 28 42 Tumor Type:overall -0.31 -5.43 4.55 1462.80 1.00 1275 27 41 1 FALSE 0.05
colorectal cancer KRAS_G12A FLT3 23 13 Metastasis -4.38 -11.84 0.14 552.95 1.00 920 23 13 0 TRUE 0.81
colorectal cancer KRAS_G12A FLT3 32 39 Primary -4.42 -11.72 0.06 521.27 1.00 1432 32 39 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A FLT3 25 41 Metastasis -0.78 -4.44 1.06 1138.49 1.00 1369 25 41 0 TRUE 0.23
non-small cell lung cancer KRAS_G12A FLT3 66 40 Primary -0.04 -2.04 1.42 1025.94 1.00 2270 64 38 2 TRUE 0.02
colorectal cancer KRAS_G12A FLT3 55 52 Tumor Type:overall -4.32 -11.69 0.19 546.20 1.00 2352 55 52 0 TRUE 0.81
non-small cell lung cancer KRAS_G12A FLT3 91 81 Tumor Type:overall -0.39 -2.91 1.41 1134.31 1.00 3639 89 79 2 TRUE 0.14
colorectal cancer KRAS_G12A MSH2 22 22 Metastasis -1.10 -4.80 0.76 25.89 1.07 839 22 22 0 TRUE 0.35
colorectal cancer KRAS_G12A MSH2 28 61 Primary -0.81 -3.51 0.75 30.50 1.07 1269 27 60 1 TRUE 0.33
non-small cell lung cancer KRAS_G12A MSH2 25 24 Metastasis -4.35 -11.24 0.13 119.62 1.04 1336 25 24 0 TRUE 0.78
non-small cell lung cancer KRAS_G12A MSH2 63 32 Primary -4.41 -11.45 0.12 108.86 1.03 2204 63 32 0 TRUE 0.80
colorectal cancer KRAS_G12A MSH2 50 83 Tumor Type:overall -0.95 -4.16 0.89 34.41 1.06 2108 49 82 1 TRUE 0.33
non-small cell lung cancer KRAS_G12A MSH2 88 56 Tumor Type:overall -4.34 -11.24 0.11 116.33 1.04 3540 88 56 0 TRUE 0.79
non-small cell lung cancer KRAS_G12A DIS3 25 27 Metastasis 0.12 -2.60 1.66 355.59 1.01 1330 25 27 0 FALSE 0.04
non-small cell lung cancer KRAS_G12A DIS3 63 38 Primary 0.64 -1.21 1.84 176.87 1.02 2202 60 35 3 FALSE 0.43
non-small cell lung cancer KRAS_G12A DIS3 88 65 Tumor Type:overall 0.42 -1.58 1.90 248.32 1.01 3532 85 62 3 FALSE 0.18
colorectal cancer KRAS_G12A AXL 22 22 Metastasis -1.42 -5.02 0.76 1271.30 1.00 838 22 22 0 FALSE 0.43
colorectal cancer KRAS_G12A AXL 28 66 Primary -1.08 -3.79 0.81 1227.32 1.00 1258 27 65 1 FALSE 0.44
colorectal cancer KRAS_G12A AXL 50 88 Tumor Type:overall -1.20 -4.17 0.97 1273.98 1.00 2096 49 87 1 FALSE 0.43
colorectal cancer KRAS_G12A PIK3CG 22 34 Metastasis 0.01 -1.61 1.31 1364.99 1.00 826 21 33 1 FALSE 0.01
colorectal cancer KRAS_G12A PIK3CG 28 73 Primary 0.07 -1.43 1.24 1107.29 1.00 1253 26 71 2 FALSE 0.04
non-small cell lung cancer KRAS_G12A PIK3CG 25 72 Metastasis 0.08 -1.40 1.10 1000.73 1.00 1293 24 71 1 FALSE 0.05
non-small cell lung cancer KRAS_G12A PIK3CG 64 108 Primary 0.32 -0.61 1.15 585.16 1.00 2143 59 103 5 FALSE 0.33
colorectal cancer KRAS_G12A PIK3CG 50 107 Tumor Type:overall 0.05 -1.52 1.46 1307.24 1.00 2079 47 104 3 FALSE 0.02
non-small cell lung cancer KRAS_G12A PIK3CG 89 180 Tumor Type:overall 0.19 -1.16 1.24 1162.77 1.00 3436 83 174 6 FALSE 0.12
colorectal cancer KRAS_G12A MAP2K4 22 24 Metastasis 0.03 -1.75 1.47 491.70 1.01 834 21 23 1 TRUE 0.01
colorectal cancer KRAS_G12A MAP2K4 28 39 Primary -0.02 -1.87 1.40 494.09 1.01 1276 27 38 1 TRUE 0.01
colorectal cancer KRAS_G12A MAP2K4 50 63 Tumor Type:overall 0.00 -1.76 1.48 508.90 1.01 2110 48 61 2 TRUE 0.00
colorectal cancer KRAS_G12A EGFR 23 16 Metastasis -4.72 -12.22 0.05 629.61 1.00 916 23 16 0 TRUE 0.88
colorectal cancer KRAS_G12A EGFR 32 50 Primary -4.74 -12.13 -0.04 685.24 1.00 1420 32 50 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A EGFR 25 432 Metastasis -3.97 -7.08 -1.95 1271.83 1.00 1065 25 432 0 TRUE 2.44
non-small cell lung cancer KRAS_G12A EGFR 66 610 Primary -3.80 -6.64 -2.04 1228.92 1.00 1794 65 609 1 TRUE 2.92
colorectal cancer KRAS_G12A EGFR 55 66 Tumor Type:overall -4.61 -12.01 0.02 634.90 1.00 2336 55 66 0 TRUE 0.88
non-small cell lung cancer KRAS_G12A EGFR 91 1042 Tumor Type:overall -3.85 -6.63 -1.84 1252.78 1.00 2859 90 1041 1 TRUE 2.69
colorectal cancer KRAS_G12A ARID1B 22 35 Metastasis -1.36 -4.29 0.84 1110.88 1.00 827 21 34 1 TRUE 0.53
colorectal cancer KRAS_G12A ARID1B 28 105 Primary -2.15 -5.80 0.02 1074.94 1.00 1225 28 105 0 TRUE 0.80
non-small cell lung cancer KRAS_G12A ARID1B 25 55 Metastasis 0.65 -0.79 1.86 1390.56 1.00 1309 22 52 3 TRUE 0.48
non-small cell lung cancer KRAS_G12A ARID1B 63 56 Primary 0.01 -1.68 1.21 1469.72 1.00 2182 62 55 1 TRUE 0.00
colorectal cancer KRAS_G12A ARID1B 50 140 Tumor Type:overall -1.71 -4.59 0.72 1285.13 1.00 2052 49 139 1 TRUE 0.66
non-small cell lung cancer KRAS_G12A ARID1B 88 111 Tumor Type:overall 0.33 -1.28 1.89 1668.23 1.00 3491 84 107 4 TRUE 0.16
non-small cell lung cancer KRAS_G12A INSR 25 22 Metastasis -1.00 -4.47 1.03 1336.11 1.00 1335 25 22 0 FALSE 0.30
non-small cell lung cancer KRAS_G12A INSR 63 33 Primary -0.74 -3.65 1.17 1229.09 1.00 2206 62 32 1 FALSE 0.26
non-small cell lung cancer KRAS_G12A INSR 88 55 Tumor Type:overall -0.86 -3.89 1.22 1243.85 1.00 3541 87 54 1 FALSE 0.29
non-small cell lung cancer KRAS_G12A NKX2-1 25 18 Metastasis 0.05 -3.18 1.78 1290.72 1.00 1341 25 18 0 TRUE 0.01
non-small cell lung cancer KRAS_G12A NKX2-1 63 57 Primary 0.75 -0.44 1.80 1290.27 1.00 2190 59 53 4 TRUE 0.73
non-small cell lung cancer KRAS_G12A NKX2-1 88 75 Tumor Type:overall 0.44 -1.91 2.25 1345.52 1.00 3531 84 71 4 TRUE 0.17
colorectal cancer KRAS_G12A ARID5B 22 15 Metastasis -0.51 -4.16 1.48 944.89 1.00 842 22 15 0 FALSE 0.14
colorectal cancer KRAS_G12A ARID5B 28 53 Primary 0.17 -1.67 1.51 1331.20 1.00 1274 26 51 2 FALSE 0.08
colorectal cancer KRAS_G12A ARID5B 50 68 Tumor Type:overall -0.17 -2.75 1.64 1172.74 1.00 2116 48 66 2 FALSE 0.05
non-small cell lung cancer KRAS_G12A WT1 25 28 Metastasis -1.01 -3.99 0.98 95.51 1.05 1330 25 28 0 TRUE 0.35
non-small cell lung cancer KRAS_G12A WT1 63 42 Primary -0.87 -3.59 0.87 125.31 1.04 2197 62 41 1 TRUE 0.36
non-small cell lung cancer KRAS_G12A WT1 88 70 Tumor Type:overall -0.92 -3.72 1.05 116.85 1.04 3527 87 69 1 TRUE 0.35
non-small cell lung cancer KRAS_G12A MET 25 56 Metastasis -0.45 -2.02 0.88 1208.71 1.00 1356 24 55 1 TRUE 0.26
non-small cell lung cancer KRAS_G12A MET 66 109 Primary -0.52 -1.86 0.56 904.59 1.00 2211 64 107 2 TRUE 0.39
non-small cell lung cancer KRAS_G12A MET 91 165 Tumor Type:overall -0.46 -1.95 0.95 1209.40 1.00 3567 88 162 3 TRUE 0.27
non-small cell lung cancer KRAS_G12A PMS1 25 23 Metastasis -0.12 -3.33 1.56 1109.93 1.00 1335 25 23 0 TRUE 0.03
non-small cell lung cancer KRAS_G12A PMS1 63 29 Primary 0.34 -1.56 1.74 1298.11 1.00 2208 61 27 2 TRUE 0.17
non-small cell lung cancer KRAS_G12A PMS1 88 52 Tumor Type:overall 0.12 -2.20 1.76 1245.87 1.00 3543 86 50 2 TRUE 0.05
non-small cell lung cancer KRAS_G12A PIK3C3 25 26 Metastasis 0.86 -0.56 2.13 1369.51 1.00 1333 23 24 2 FALSE 0.68
non-small cell lung cancer KRAS_G12A PIK3C3 63 50 Primary 0.60 -0.74 1.66 1411.75 1.00 2189 61 48 2 FALSE 0.49
non-small cell lung cancer KRAS_G12A PIK3C3 88 76 Tumor Type:overall 0.72 -0.80 2.04 1319.58 1.00 3522 84 72 4 FALSE 0.51
colorectal cancer KRAS_G12A BRAF 23 79 Metastasis -2.01 -4.91 -0.02 1377.42 1.00 855 22 78 1 TRUE 1.02
colorectal cancer KRAS_G12A BRAF 32 174 Primary -2.48 -5.69 -0.53 990.40 1.00 1301 32 174 0 TRUE 1.16
non-small cell lung cancer KRAS_G12A BRAF 25 72 Metastasis -2.20 -5.36 -0.07 1043.21 1.00 1335 25 72 0 TRUE 0.93
non-small cell lung cancer KRAS_G12A BRAF 66 121 Primary -2.02 -4.77 -0.22 919.83 1.00 2190 65 120 1 TRUE 1.05
colorectal cancer KRAS_G12A BRAF 55 253 Tumor Type:overall -2.23 -5.27 -0.09 1287.54 1.00 2156 54 252 1 TRUE 1.04
non-small cell lung cancer KRAS_G12A BRAF 91 193 Tumor Type:overall -2.10 -5.13 -0.14 939.95 1.00 3525 90 192 1 TRUE 1.02
non-small cell lung cancer KRAS_G12A TGFBR1 25 23 Metastasis 0.18 -3.15 1.82 1141.84 1.00 1334 25 23 0 FALSE 0.05
non-small cell lung cancer KRAS_G12A TGFBR1 63 28 Primary 0.95 -0.52 2.17 1452.65 1.00 2210 60 25 3 FALSE 0.79
non-small cell lung cancer KRAS_G12A TGFBR1 88 51 Tumor Type:overall 0.56 -1.82 2.14 1578.56 1.00 3544 85 48 3 FALSE 0.23
colorectal cancer KRAS_G12A TET2 22 14 Metastasis -1.66 -6.05 1.15 1454.05 1.00 844 22 14 0 TRUE 0.44
colorectal cancer KRAS_G12A TET2 28 77 Primary -1.16 -4.09 0.83 1526.45 1.00 1252 27 76 1 TRUE 0.45
non-small cell lung cancer KRAS_G12A TET2 25 38 Metastasis -1.43 -5.21 0.78 1243.83 1.00 1321 25 38 0 TRUE 0.45
non-small cell lung cancer KRAS_G12A TET2 63 43 Primary -1.09 -4.10 0.80 1223.21 1.00 2196 62 42 1 TRUE 0.43
colorectal cancer KRAS_G12A TET2 50 91 Tumor Type:overall -1.33 -4.67 1.42 1539.57 1.00 2096 49 90 1 TRUE 0.40
non-small cell lung cancer KRAS_G12A TET2 88 81 Tumor Type:overall -1.22 -4.49 0.85 1144.31 1.00 3517 87 80 1 TRUE 0.42
colorectal cancer KRAS_G12A PDGFRB 28 46 Primary -5.10 -15.06 0.00 797.89 1.01 1267 28 46 0 TRUE 0.54
non-small cell lung cancer KRAS_G12A PDGFRB 25 37 Metastasis -0.28 -2.27 1.20 866.98 1.00 1323 24 36 1 TRUE 0.12
non-small cell lung cancer KRAS_G12A PDGFRB 63 55 Primary -0.42 -2.45 0.94 803.29 1.00 2188 62 54 1 TRUE 0.20
colorectal cancer KRAS_G12A PDGFRB 28 46 Tumor Type:overall -3.51 -10.84 3.36 1197.52 1.00 1267 28 46 0 TRUE 0.49
non-small cell lung cancer KRAS_G12A PDGFRB 88 92 Tumor Type:overall -0.34 -2.45 1.22 991.73 1.00 3511 86 90 2 TRUE 0.15
colorectal cancer KRAS_G12A CARD11 22 29 Metastasis -0.58 -5.21 1.36 1384.84 1.00 830 22 29 0 FALSE 0.14
colorectal cancer KRAS_G12A CARD11 29 99 Primary 0.71 -0.39 1.68 1487.97 1.00 1227 24 94 5 FALSE 0.73
non-small cell lung cancer KRAS_G12A CARD11 25 43 Metastasis -0.34 -3.49 1.06 633.17 1.00 1315 25 43 0 FALSE 0.11
non-small cell lung cancer KRAS_G12A CARD11 63 87 Primary 0.24 -1.03 1.21 1221.43 1.01 2158 59 83 4 FALSE 0.17
colorectal cancer KRAS_G12A CARD11 51 128 Tumor Type:overall 0.07 -2.88 1.89 1534.49 1.00 2057 46 123 5 FALSE 0.02
non-small cell lung cancer KRAS_G12A CARD11 88 130 Tumor Type:overall -0.03 -1.98 1.34 1399.18 1.00 3473 84 126 4 FALSE 0.01
colorectal cancer KRAS_G12A DNMT3A 22 11 Metastasis -4.47 -11.62 0.33 1175.03 1.00 845 22 11 0 TRUE 0.81
colorectal cancer KRAS_G12A DNMT3A 28 45 Primary -4.47 -11.16 -0.06 919.57 1.00 1274 28 45 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A DNMT3A 25 27 Metastasis -4.59 -11.53 -0.37 335.50 1.01 1330 25 27 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A DNMT3A 63 50 Primary -4.61 -11.39 -0.58 362.02 1.01 2186 63 50 0 TRUE 0.94
colorectal cancer KRAS_G12A DNMT3A 50 56 Tumor Type:overall -4.37 -11.08 0.25 1188.31 1.00 2119 50 56 0 TRUE 0.84
non-small cell lung cancer KRAS_G12A DNMT3A 88 77 Tumor Type:overall -4.55 -11.48 -0.41 400.69 1.01 3516 88 77 0 TRUE 0.91
colorectal cancer KRAS_G12A MSH6 22 23 Metastasis -0.88 -4.10 1.05 1451.86 1.00 836 22 23 0 TRUE 0.27
colorectal cancer KRAS_G12A MSH6 28 77 Primary -0.26 -2.26 1.17 1512.85 1.00 1253 26 75 2 TRUE 0.12
colorectal cancer KRAS_G12A MSH6 50 100 Tumor Type:overall -0.55 -3.31 1.32 1523.65 1.00 2089 48 98 2 TRUE 0.20
non-small cell lung cancer KRAS_G12A MAX 25 16 Metastasis 1.26 -0.19 2.38 876.51 1.00 1342 24 15 1 FALSE 1.32
non-small cell lung cancer KRAS_G12A MAX 63 39 Primary 1.32 0.24 2.24 751.01 1.00 2201 59 35 4 FALSE 2.06
non-small cell lung cancer KRAS_G12A MAX 88 55 Tumor Type:overall 1.29 -0.09 2.52 785.86 1.00 3543 83 50 5 FALSE 1.26
non-small cell lung cancer KRAS_G12A INPP4B 25 53 Metastasis 0.49 -0.76 1.54 1343.16 1.00 1311 23 51 2 FALSE 0.41
non-small cell lung cancer KRAS_G12A INPP4B 63 73 Primary 0.44 -0.66 1.35 1377.61 1.00 2171 60 70 3 FALSE 0.40
non-small cell lung cancer KRAS_G12A INPP4B 88 126 Tumor Type:overall 0.47 -0.84 1.65 1450.55 1.00 3482 83 121 5 FALSE 0.34
non-small cell lung cancer KRAS_G12A NFE2L2 25 43 Metastasis -1.65 -4.68 0.44 705.59 1.00 1319 25 43 0 FALSE 0.66
non-small cell lung cancer KRAS_G12A NFE2L2 63 81 Primary -1.53 -4.32 0.40 647.52 1.00 2163 62 80 1 FALSE 0.70
non-small cell lung cancer KRAS_G12A NFE2L2 88 124 Tumor Type:overall -1.58 -4.52 0.50 674.63 1.00 3482 87 123 1 FALSE 0.66
colorectal cancer KRAS_G12A SOX9 23 72 Metastasis 0.56 -0.48 1.46 1524.45 1.00 792 20 69 3 FALSE 0.59
colorectal cancer KRAS_G12A SOX9 30 192 Primary 0.71 -0.12 1.45 1446.34 1.00 1145 22 184 8 FALSE 1.13
colorectal cancer KRAS_G12A SOX9 53 264 Tumor Type:overall 0.64 -0.56 1.82 1588.04 1.00 1937 42 253 11 FALSE 0.57
colorectal cancer KRAS_G12A ARAF 22 18 Metastasis -4.33 -11.12 0.07 675.03 1.01 838 22 18 0 FALSE 0.86
colorectal cancer KRAS_G12A ARAF 28 37 Primary -4.36 -11.34 0.00 924.00 1.01 1281 28 37 0 FALSE 0.82
non-small cell lung cancer KRAS_G12A ARAF 25 30 Metastasis -0.35 -2.73 1.29 1295.56 1.00 1331 25 30 0 FALSE 0.13
non-small cell lung cancer KRAS_G12A ARAF 63 39 Primary 0.00 -1.84 1.39 1174.18 1.00 2203 61 37 2 FALSE 0.00
colorectal cancer KRAS_G12A ARAF 50 55 Tumor Type:overall -4.28 -10.87 0.06 712.84 1.01 2119 50 55 0 FALSE 0.85
non-small cell lung cancer KRAS_G12A ARAF 88 69 Tumor Type:overall -0.15 -2.14 1.38 1344.43 1.00 3534 86 67 2 FALSE 0.06
non-small cell lung cancer KRAS_G12A JAK2 26 41 Metastasis 0.21 -1.76 1.77 1487.82 1.00 1370 24 39 2 TRUE 0.09
non-small cell lung cancer KRAS_G12A JAK2 66 37 Primary -0.92 -4.48 0.96 1217.20 1.00 2270 66 37 0 TRUE 0.26
non-small cell lung cancer KRAS_G12A JAK2 92 78 Tumor Type:overall -0.34 -2.95 1.64 1374.78 1.00 3640 90 76 2 TRUE 0.11
colorectal cancer KRAS_G12A SMAD2 22 26 Metastasis -0.30 -2.41 1.35 1264.32 1.00 833 21 25 1 TRUE 0.13
colorectal cancer KRAS_G12A SMAD2 28 76 Primary -0.52 -2.54 0.94 1298.95 1.00 1247 27 75 1 TRUE 0.26
colorectal cancer KRAS_G12A SMAD2 50 102 Tumor Type:overall -0.43 -2.73 1.34 1226.27 1.00 2080 48 100 2 TRUE 0.18
non-small cell lung cancer KRAS_G12A TP63 25 33 Metastasis -0.55 -3.50 1.21 28.88 1.08 1325 24 32 1 FALSE 0.17
non-small cell lung cancer KRAS_G12A TP63 63 39 Primary -1.02 -4.78 1.04 22.54 1.10 2198 63 39 0 FALSE 0.28
non-small cell lung cancer KRAS_G12A TP63 88 72 Tumor Type:overall -0.78 -4.00 1.18 22.02 1.10 3523 87 71 1 FALSE 0.22
non-small cell lung cancer KRAS_G12A MYOD1 25 25 Metastasis -4.25 -10.96 0.65 70.13 1.04 1332 25 25 0 FALSE 0.75
non-small cell lung cancer KRAS_G12A MYOD1 63 33 Primary -4.28 -10.99 0.51 73.70 1.04 2206 63 33 0 FALSE 0.77
non-small cell lung cancer KRAS_G12A MYOD1 88 58 Tumor Type:overall -4.19 -10.85 0.55 72.79 1.04 3538 88 58 0 FALSE 0.75
colorectal cancer KRAS_G12A FGFR1 23 17 Metastasis -4.40 -11.56 0.14 1012.72 1.00 915 23 17 0 TRUE 0.84
colorectal cancer KRAS_G12A FGFR1 32 34 Primary -4.38 -11.62 0.10 978.59 1.00 1435 32 34 0 TRUE 0.85
colorectal cancer KRAS_G12A FGFR1 55 51 Tumor Type:overall -4.35 -11.36 0.17 973.65 1.00 2350 55 51 0 TRUE 0.84
colorectal cancer KRAS_G12A MITF 22 14 Metastasis -4.21 -11.34 0.31 973.90 1.00 842 22 14 0 FALSE 0.75
colorectal cancer KRAS_G12A MITF 28 38 Primary -4.26 -11.18 0.10 997.04 1.00 1275 28 38 0 FALSE 0.77
colorectal cancer KRAS_G12A MITF 50 52 Tumor Type:overall -4.14 -11.12 0.43 951.84 1.00 2117 50 52 0 FALSE 0.75
non-small cell lung cancer KRAS_G12A BTK 25 28 Metastasis -4.55 -11.70 -0.06 1388.57 1.00 1329 25 28 0 TRUE 0.85
non-small cell lung cancer KRAS_G12A BTK 63 32 Primary -4.56 -11.70 -0.10 1437.16 1.00 2204 63 32 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A BTK 88 60 Tumor Type:overall -4.47 -11.57 -0.09 1373.99 1.00 3533 88 60 0 TRUE 0.86
non-small cell lung cancer KRAS_G12A GLI1 23 37 Metastasis -1.66 -4.68 0.45 1313.11 1.00 1179 23 37 0 FALSE 0.68
non-small cell lung cancer KRAS_G12A GLI1 60 69 Primary -1.49 -4.17 0.36 1359.45 1.00 1957 59 68 1 FALSE 0.71
non-small cell lung cancer KRAS_G12A GLI1 83 106 Tumor Type:overall -1.56 -4.28 0.48 1292.61 1.00 3136 82 105 1 FALSE 0.70
non-small cell lung cancer KRAS_G12A ZFHX3 23 75 Metastasis 0.12 -1.19 1.22 1430.04 1.00 1141 21 73 2 FALSE 0.07
non-small cell lung cancer KRAS_G12A ZFHX3 60 89 Primary 0.07 -1.01 0.98 1041.65 1.00 1940 57 86 3 FALSE 0.05
non-small cell lung cancer KRAS_G12A ZFHX3 83 164 Tumor Type:overall 0.10 -1.27 1.32 1337.75 1.00 3081 78 159 5 FALSE 0.05
non-small cell lung cancer KRAS_G12A MGA 23 82 Metastasis 0.14 -1.11 1.35 1093.69 1.00 1150 20 79 3 FALSE 0.08
non-small cell lung cancer KRAS_G12A MGA 60 115 Primary -0.27 -1.58 0.77 1176.43 1.00 1915 58 113 2 FALSE 0.19
non-small cell lung cancer KRAS_G12A MGA 83 197 Tumor Type:overall -0.06 -1.50 1.24 1387.78 1.00 3065 78 192 5 FALSE 0.03
non-small cell lung cancer KRAS_G12A ANKRD11 23 27 Metastasis -0.52 -3.42 1.20 1268.12 1.00 1188 23 27 0 FALSE 0.17
non-small cell lung cancer KRAS_G12A ANKRD11 60 45 Primary -0.12 -1.95 1.26 1120.23 1.00 1980 58 43 2 FALSE 0.05
non-small cell lung cancer KRAS_G12A ANKRD11 83 72 Tumor Type:overall -0.29 -2.40 1.34 1165.36 1.00 3168 81 70 2 FALSE 0.12
non-small cell lung cancer KRAS_G12A PGR 23 34 Metastasis -1.44 -4.81 0.59 1081.41 1.00 1178 23 34 0 FALSE 0.55
non-small cell lung cancer KRAS_G12A PGR 60 53 Primary -1.25 -4.01 0.55 1265.41 1.00 1973 59 52 1 FALSE 0.55
non-small cell lung cancer KRAS_G12A PGR 83 87 Tumor Type:overall -1.33 -4.39 0.78 1187.95 1.00 3151 82 86 1 FALSE 0.52
non-small cell lung cancer KRAS_G12A PLCG2 23 24 Metastasis -0.76 -3.70 1.51 143.06 1.02 1190 22 23 1 FALSE 0.24
non-small cell lung cancer KRAS_G12A PLCG2 60 38 Primary -1.36 -4.94 0.88 273.27 1.00 1990 60 38 0 FALSE 0.36
non-small cell lung cancer KRAS_G12A PLCG2 83 62 Tumor Type:overall -1.04 -4.20 1.24 166.76 1.01 3180 82 61 1 FALSE 0.33
non-small cell lung cancer KRAS_G12A POLD1 23 25 Metastasis -4.65 -11.68 0.02 944.51 1.00 1186 23 25 0 TRUE 0.89
non-small cell lung cancer KRAS_G12A POLD1 60 33 Primary -4.68 -11.68 -0.01 919.97 1.00 1991 60 33 0 TRUE 0.91
non-small cell lung cancer KRAS_G12A POLD1 83 58 Tumor Type:overall -4.57 -11.51 0.09 817.76 1.00 3177 83 58 0 TRUE 0.90
non-small cell lung cancer KRAS_G12A INHBA 23 32 Metastasis -0.95 -3.74 1.18 1293.33 1.00 1185 22 31 1 FALSE 0.36
non-small cell lung cancer KRAS_G12A INHBA 60 55 Primary -1.53 -5.10 0.46 1028.15 1.00 1969 60 55 0 FALSE 0.52
non-small cell lung cancer KRAS_G12A INHBA 83 87 Tumor Type:overall -1.20 -4.13 0.91 1278.00 1.00 3154 82 86 1 FALSE 0.47
colorectal cancer KRAS_G12A AMER1 22 51 Metastasis -2.19 -6.94 0.05 102.61 1.01 807 22 51 0 FALSE 0.72
colorectal cancer KRAS_G12A AMER1 28 118 Primary -1.94 -6.80 0.10 78.53 1.02 1207 27 117 1 FALSE 0.71
non-small cell lung cancer KRAS_G12A AMER1 25 54 Metastasis 0.32 -0.92 1.15 39.32 1.09 1313 24 53 1 FALSE 0.27
non-small cell lung cancer KRAS_G12A AMER1 63 95 Primary 0.38 -0.71 1.12 26.97 1.12 2156 59 91 4 FALSE 0.42
colorectal cancer KRAS_G12A AMER1 50 169 Tumor Type:overall -2.02 -6.89 0.08 80.78 1.02 2014 49 168 1 FALSE 0.70
non-small cell lung cancer KRAS_G12A AMER1 88 149 Tumor Type:overall 0.35 -0.88 1.17 40.52 1.08 3469 83 144 5 FALSE 0.29
non-small cell lung cancer KRAS_G12A EPHA7 23 54 Metastasis -0.66 -2.50 0.83 1098.60 1.00 1161 22 53 1 FALSE 0.35
non-small cell lung cancer KRAS_G12A EPHA7 60 75 Primary -0.78 -2.49 0.50 1177.80 1.00 1952 59 74 1 FALSE 0.49
non-small cell lung cancer KRAS_G12A EPHA7 83 129 Tumor Type:overall -0.72 -2.60 0.82 1079.17 1.00 3113 81 127 2 FALSE 0.38
colorectal cancer KRAS_G12C SPEN 37 45 Metastasis -5.34 -12.27 -1.15 242.55 1.00 805 37 45 0 FALSE 1.12
colorectal cancer KRAS_G12C SPEN 29 110 Primary -5.34 -12.24 -1.21 229.30 1.00 1234 29 110 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C SPEN 167 71 Metastasis -0.78 -1.78 0.03 1426.22 1.00 1177 162 66 5 FALSE 1.03
non-small cell lung cancer KRAS_G12C SPEN 289 50 Primary -1.18 -2.51 -0.13 1420.36 1.00 1965 287 48 2 FALSE 1.31
colorectal cancer KRAS_G12C SPEN 66 155 Tumor Type:overall -5.22 -12.00 -1.03 240.88 1.00 2039 66 155 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C SPEN 456 121 Tumor Type:overall -0.95 -2.37 0.49 1461.67 1.00 3142 449 114 7 FALSE 0.73
colorectal cancer KRAS_G12C KMT2C 37 49 Metastasis -5.67 -12.83 -1.10 1457.33 1.00 799 37 49 0 FALSE 1.16
colorectal cancer KRAS_G12C KMT2C 29 149 Primary -5.63 -12.56 -1.33 1459.69 1.00 1212 29 149 0 FALSE 1.23
non-small cell lung cancer KRAS_G12C KMT2C 167 89 Metastasis 0.00 -0.55 0.45 1209.75 1.00 1144 158 80 9 FALSE 0.00
non-small cell lung cancer KRAS_G12C KMT2C 289 133 Primary 0.09 -0.34 0.53 734.03 1.00 1905 269 113 20 FALSE 0.17
colorectal cancer KRAS_G12C KMT2C 66 198 Tumor Type:overall -5.49 -12.25 -1.10 1422.77 1.00 2011 66 198 0 FALSE 1.19
non-small cell lung cancer KRAS_G12C KMT2C 456 222 Tumor Type:overall 0.05 -0.48 0.55 941.47 1.00 3049 427 193 29 FALSE 0.07
colorectal cancer KRAS_G12C TP53 45 701 Metastasis -0.57 -1.15 -0.03 1279.15 1.00 270 20 676 25 TRUE 1.30
colorectal cancer KRAS_G12C TP53 35 1018 Primary -0.25 -0.83 0.39 1540.68 1.00 552 13 996 22 TRUE 0.37
non-small cell lung cancer KRAS_G12C TP53 177 855 Metastasis -0.56 -0.85 -0.28 1538.23 1.00 529 95 773 82 TRUE 4.07
non-small cell lung cancer KRAS_G12C TP53 305 1201 Primary -0.76 -1.01 -0.52 1427.55 1.00 1063 207 1103 98 TRUE 8.99
colorectal cancer KRAS_G12C TP53 80 1719 Tumor Type:overall -0.40 -1.67 0.86 1288.41 1.00 822 33 1672 47 TRUE 0.27
non-small cell lung cancer KRAS_G12C TP53 482 2056 Tumor Type:overall -0.66 -1.21 -0.08 1628.01 1.00 1592 302 1876 180 TRUE 1.58
colorectal cancer KRAS_G12C ATRX 37 33 Metastasis -1.46 -4.48 0.54 1446.01 1.00 813 36 32 1 TRUE 0.61
colorectal cancer KRAS_G12C ATRX 29 86 Primary -2.13 -5.64 0.04 1331.34 1.00 1242 29 86 0 TRUE 0.82
non-small cell lung cancer KRAS_G12C ATRX 167 79 Metastasis 0.50 -0.19 0.96 1336.59 1.00 1158 156 68 11 TRUE 1.12
non-small cell lung cancer KRAS_G12C ATRX 293 129 Primary 0.77 0.37 1.18 1131.38 1.00 1926 260 96 33 TRUE 3.59
colorectal cancer KRAS_G12C ATRX 66 119 Tumor Type:overall -1.76 -4.97 0.61 1515.38 1.00 2055 65 118 1 TRUE 0.69
non-small cell lung cancer KRAS_G12C ATRX 460 208 Tumor Type:overall 0.62 -0.15 1.23 1387.40 1.00 3084 416 164 44 TRUE 1.00
colorectal cancer KRAS_G12C ATR 37 30 Metastasis -5.12 -12.46 -0.58 1253.84 1.00 819 37 30 0 FALSE 1.03
colorectal cancer KRAS_G12C ATR 29 84 Primary -5.20 -12.48 -0.75 1404.13 1.00 1250 29 84 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C ATR 166 53 Metastasis 0.07 -0.66 0.57 653.11 1.00 1170 161 48 5 FALSE 0.08
non-small cell lung cancer KRAS_G12C ATR 289 76 Primary 0.18 -0.37 0.68 1119.82 1.00 1949 276 63 13 FALSE 0.31
colorectal cancer KRAS_G12C ATR 66 114 Tumor Type:overall -5.04 -11.73 -0.69 1171.74 1.00 2069 66 114 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C ATR 455 129 Tumor Type:overall 0.12 -0.52 0.73 910.89 1.00 3119 437 111 18 FALSE 0.15
colorectal cancer KRAS_G12C PDGFRA 45 15 Metastasis 0.25 -1.74 1.68 1265.89 1.00 895 44 14 1 TRUE 0.11
colorectal cancer KRAS_G12C PDGFRA 32 45 Primary 0.47 -1.08 1.69 1415.54 1.00 1426 30 43 2 TRUE 0.29
non-small cell lung cancer KRAS_G12C PDGFRA 172 64 Metastasis 0.55 0.06 1.05 1313.53 1.00 1212 159 51 13 TRUE 1.50
non-small cell lung cancer KRAS_G12C PDGFRA 301 84 Primary 0.47 -0.05 0.91 1438.15 1.00 2009 286 69 15 TRUE 1.32
colorectal cancer KRAS_G12C PDGFRA 77 60 Tumor Type:overall 0.35 -1.59 2.23 1564.38 1.00 2321 74 57 3 TRUE 0.14
non-small cell lung cancer KRAS_G12C PDGFRA 473 148 Tumor Type:overall 0.52 -0.08 1.11 1363.84 1.00 3221 445 120 28 TRUE 1.05
colorectal cancer KRAS_G12C FBXW7 46 90 Metastasis -0.12 -1.15 0.80 1477.89 1.00 833 42 86 4 TRUE 0.09
colorectal cancer KRAS_G12C FBXW7 33 249 Primary -0.02 -0.90 0.79 1389.69 1.00 1253 27 243 6 TRUE 0.01
non-small cell lung cancer KRAS_G12C FBXW7 172 32 Metastasis -0.21 -1.05 0.56 1047.88 1.00 1234 168 28 4 TRUE 0.21
non-small cell lung cancer KRAS_G12C FBXW7 302 54 Primary -0.27 -1.09 0.46 1020.63 1.00 2026 297 49 5 TRUE 0.30
colorectal cancer KRAS_G12C FBXW7 79 339 Tumor Type:overall -0.06 -1.42 1.30 1384.18 1.00 2086 69 329 10 TRUE 0.03
non-small cell lung cancer KRAS_G12C FBXW7 474 86 Tumor Type:overall -0.23 -1.08 0.57 1075.30 1.00 3260 465 77 9 TRUE 0.22
colorectal cancer KRAS_G12C MAP3K1 37 30 Metastasis -0.23 -2.10 1.33 1498.86 1.00 815 35 28 2 FALSE 0.10
colorectal cancer KRAS_G12C MAP3K1 29 62 Primary -1.35 -5.43 0.70 1328.41 1.00 1258 29 62 0 FALSE 0.41
non-small cell lung cancer KRAS_G12C MAP3K1 166 30 Metastasis 0.82 0.13 1.46 549.30 1.00 1194 159 23 7 FALSE 1.84
non-small cell lung cancer KRAS_G12C MAP3K1 289 37 Primary 0.80 0.16 1.44 546.69 1.00 1982 280 28 9 FALSE 1.91
colorectal cancer KRAS_G12C MAP3K1 66 92 Tumor Type:overall -0.71 -3.36 1.31 1419.47 1.00 2073 64 90 2 FALSE 0.24
non-small cell lung cancer KRAS_G12C MAP3K1 455 67 Tumor Type:overall 0.80 0.05 1.50 627.63 1.00 3176 439 51 16 FALSE 1.39
colorectal cancer KRAS_G12C NSD1 37 23 Metastasis -1.82 -5.53 0.45 1429.21 1.00 820 37 23 0 FALSE 0.60
colorectal cancer KRAS_G12C NSD1 29 63 Primary -1.23 -4.04 0.70 1389.83 1.00 1261 28 62 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C NSD1 166 34 Metastasis -0.16 -0.89 0.55 514.72 1.01 1187 162 30 4 FALSE 0.17
non-small cell lung cancer KRAS_G12C NSD1 289 56 Primary -0.18 -0.90 0.50 539.88 1.01 1959 283 50 6 FALSE 0.21
colorectal cancer KRAS_G12C NSD1 66 86 Tumor Type:overall -1.47 -4.66 0.85 1337.94 1.00 2081 65 85 1 FALSE 0.53
non-small cell lung cancer KRAS_G12C NSD1 455 90 Tumor Type:overall -0.17 -0.93 0.53 682.19 1.00 3146 445 80 10 FALSE 0.17
colorectal cancer KRAS_G12C FLT4 37 41 Metastasis -1.80 -4.74 0.22 1265.94 1.00 803 36 40 1 TRUE 0.83
colorectal cancer KRAS_G12C FLT4 29 98 Primary -2.41 -6.25 -0.22 1388.88 1.00 1229 29 98 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C FLT4 166 37 Metastasis 0.40 -0.21 1.04 1079.35 1.00 1188 158 29 8 TRUE 0.69
non-small cell lung cancer KRAS_G12C FLT4 290 65 Primary 0.28 -0.33 0.82 1195.98 1.00 1955 281 56 9 TRUE 0.48
colorectal cancer KRAS_G12C FLT4 66 139 Tumor Type:overall -2.03 -5.02 0.22 1183.53 1.00 2032 65 138 1 TRUE 0.88
non-small cell lung cancer KRAS_G12C FLT4 456 102 Tumor Type:overall 0.34 -0.32 0.98 1266.25 1.00 3143 439 85 17 TRUE 0.49
colorectal cancer KRAS_G12C PTPRD 37 28 Metastasis -1.35 -4.09 0.72 1381.16 1.00 818 36 27 1 FALSE 0.54
colorectal cancer KRAS_G12C PTPRD 29 75 Primary -1.95 -5.48 0.29 1435.25 1.00 1253 29 75 0 FALSE 0.66
non-small cell lung cancer KRAS_G12C PTPRD 172 165 Metastasis 0.42 0.02 0.85 947.24 1.00 1106 141 134 31 FALSE 1.29
non-small cell lung cancer KRAS_G12C PTPRD 293 226 Primary 0.08 -0.36 0.43 559.88 1.01 1836 266 199 27 FALSE 0.15
colorectal cancer KRAS_G12C PTPRD 66 103 Tumor Type:overall -1.60 -4.71 0.54 1403.53 1.00 2071 65 102 1 FALSE 0.59
non-small cell lung cancer KRAS_G12C PTPRD 465 391 Tumor Type:overall 0.24 -0.47 0.81 1358.29 1.00 2942 407 333 58 FALSE 0.31
colorectal cancer KRAS_G12C RET 45 20 Metastasis 0.66 -0.72 1.84 1313.59 1.00 891 43 18 2 TRUE 0.50
colorectal cancer KRAS_G12C RET 32 45 Primary 0.65 -0.79 1.84 1549.06 1.00 1424 30 43 2 TRUE 0.49
non-small cell lung cancer KRAS_G12C RET 171 39 Metastasis 0.68 0.08 1.31 1409.25 1.00 1231 161 29 10 TRUE 1.53
non-small cell lung cancer KRAS_G12C RET 300 54 Primary 0.53 -0.07 1.07 1148.51 1.00 2032 291 45 9 TRUE 1.13
colorectal cancer KRAS_G12C RET 77 65 Tumor Type:overall 0.64 -1.04 2.16 1533.27 1.00 2315 73 61 4 TRUE 0.36
non-small cell lung cancer KRAS_G12C RET 471 93 Tumor Type:overall 0.61 -0.10 1.31 1393.75 1.00 3263 452 74 19 TRUE 1.00
colorectal cancer KRAS_G12C KDM5A 37 24 Metastasis -5.14 -12.01 -0.58 1211.56 1.00 826 37 24 0 FALSE 1.04
colorectal cancer KRAS_G12C KDM5A 29 72 Primary -5.17 -12.04 -0.88 1281.57 1.00 1248 29 72 0 FALSE 1.11
non-small cell lung cancer KRAS_G12C KDM5A 166 24 Metastasis 0.41 -0.42 1.09 1176.36 1.00 1195 163 21 3 FALSE 0.53
non-small cell lung cancer KRAS_G12C KDM5A 290 49 Primary 0.53 -0.15 1.17 1130.52 1.00 1974 279 38 11 FALSE 0.98
colorectal cancer KRAS_G12C KDM5A 66 96 Tumor Type:overall -5.03 -11.55 -0.53 1201.94 1.00 2074 66 96 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C KDM5A 456 73 Tumor Type:overall 0.47 -0.36 1.20 1371.91 1.00 3169 442 59 14 FALSE 0.59
colorectal cancer KRAS_G12C PIK3C2G 37 20 Metastasis -1.81 -5.46 0.59 1406.99 1.00 824 37 20 0 FALSE 0.61
colorectal cancer KRAS_G12C PIK3C2G 29 67 Primary -1.25 -4.26 0.68 1497.99 1.00 1257 28 66 1 FALSE 0.49
non-small cell lung cancer KRAS_G12C PIK3C2G 166 52 Metastasis -0.19 -0.81 0.45 1233.14 1.00 1173 160 46 6 FALSE 0.26
non-small cell lung cancer KRAS_G12C PIK3C2G 290 79 Primary -0.22 -0.84 0.34 1158.62 1.00 1942 282 71 8 FALSE 0.35
colorectal cancer KRAS_G12C PIK3C2G 66 87 Tumor Type:overall -1.47 -4.72 0.97 1434.09 1.00 2081 65 86 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C PIK3C2G 456 131 Tumor Type:overall -0.20 -0.88 0.41 1244.90 1.00 3115 442 117 14 FALSE 0.28
non-small cell lung cancer KRAS_G12C TSHR 167 34 Metastasis 0.47 -0.26 1.17 1458.33 1.00 1189 161 28 6 TRUE 0.71
non-small cell lung cancer KRAS_G12C TSHR 289 35 Primary 0.46 -0.24 1.13 1363.69 1.00 1982 282 28 7 TRUE 0.70
non-small cell lung cancer KRAS_G12C TSHR 456 69 Tumor Type:overall 0.46 -0.40 1.26 1329.95 1.00 3171 443 56 13 TRUE 0.54
colorectal cancer KRAS_G12C CREBBP 37 37 Metastasis -0.30 -2.01 1.14 1449.17 1.00 814 35 35 2 TRUE 0.15
colorectal cancer KRAS_G12C CREBBP 29 151 Primary -1.13 -3.18 0.19 1357.52 1.00 1199 28 150 1 TRUE 0.73
non-small cell lung cancer KRAS_G12C CREBBP 166 67 Metastasis -0.34 -1.17 0.31 1186.53 1.00 1162 161 62 5 TRUE 0.43
non-small cell lung cancer KRAS_G12C CREBBP 289 75 Primary -0.13 -0.79 0.47 952.57 1.00 1946 279 65 10 TRUE 0.17
colorectal cancer KRAS_G12C CREBBP 66 188 Tumor Type:overall -0.70 -3.03 1.37 1445.71 1.00 2013 63 185 3 TRUE 0.29
non-small cell lung cancer KRAS_G12C CREBBP 455 142 Tumor Type:overall -0.24 -1.16 0.55 1303.74 1.00 3108 440 127 15 TRUE 0.22
non-small cell lung cancer KRAS_G12C BRIP1 166 30 Metastasis 0.31 -0.56 1.20 200.82 1.02 1193 159 23 7 TRUE 0.30
non-small cell lung cancer KRAS_G12C BRIP1 289 40 Primary -0.09 -1.06 0.74 461.65 1.00 1973 286 37 3 TRUE 0.07
non-small cell lung cancer KRAS_G12C BRIP1 455 70 Tumor Type:overall 0.11 -0.87 1.09 460.82 1.01 3166 445 60 10 TRUE 0.07
colorectal cancer KRAS_G12C AXIN2 37 26 Metastasis -5.14 -11.83 -0.72 1262.10 1.00 817 37 26 0 TRUE 1.07
colorectal cancer KRAS_G12C AXIN2 29 89 Primary -5.21 -12.19 -0.98 1177.86 1.00 1238 29 89 0 TRUE 1.10
non-small cell lung cancer KRAS_G12C AXIN2 166 26 Metastasis 0.24 -0.49 0.98 111.38 1.03 1194 162 22 4 TRUE 0.26
non-small cell lung cancer KRAS_G12C AXIN2 289 36 Primary 0.25 -0.42 0.97 93.67 1.04 1979 283 30 6 TRUE 0.30
colorectal cancer KRAS_G12C AXIN2 66 115 Tumor Type:overall -5.02 -11.51 -0.62 1273.74 1.00 2055 66 115 0 TRUE 1.07
non-small cell lung cancer KRAS_G12C AXIN2 455 62 Tumor Type:overall 0.25 -0.56 1.04 143.34 1.03 3173 445 52 10 TRUE 0.24
colorectal cancer KRAS_G12C DOT1L 37 23 Metastasis -1.82 -5.66 0.46 1460.60 1.00 822 37 23 0 FALSE 0.56
colorectal cancer KRAS_G12C DOT1L 29 61 Primary -1.28 -4.20 0.59 1622.54 1.00 1260 28 60 1 FALSE 0.52
non-small cell lung cancer KRAS_G12C DOT1L 167 46 Metastasis 0.12 -0.64 0.70 1030.26 1.00 1176 161 40 6 FALSE 0.14
non-small cell lung cancer KRAS_G12C DOT1L 289 61 Primary 0.14 -0.50 0.69 902.63 1.00 1959 280 52 9 FALSE 0.19
colorectal cancer KRAS_G12C DOT1L 66 84 Tumor Type:overall -1.51 -4.84 0.69 1570.64 1.00 2082 65 83 1 FALSE 0.54
non-small cell lung cancer KRAS_G12C DOT1L 456 107 Tumor Type:overall 0.13 -0.64 0.77 1232.67 1.00 3135 441 92 15 FALSE 0.14
colorectal cancer KRAS_G12C PTPRS 37 63 Metastasis -0.79 -2.33 0.55 1629.88 1.00 789 35 61 2 FALSE 0.54
colorectal cancer KRAS_G12C PTPRS 29 191 Primary -1.33 -3.12 -0.02 1454.41 1.00 1162 28 190 1 FALSE 0.99
non-small cell lung cancer KRAS_G12C PTPRS 170 32 Metastasis 0.74 0.09 1.45 1357.71 1.00 1194 161 23 9 FALSE 1.50
non-small cell lung cancer KRAS_G12C PTPRS 289 48 Primary 0.56 -0.10 1.18 1234.57 1.00 1970 281 40 8 FALSE 1.09
colorectal cancer KRAS_G12C PTPRS 66 254 Tumor Type:overall -1.03 -2.96 0.80 1578.56 1.00 1951 63 251 3 FALSE 0.57
non-small cell lung cancer KRAS_G12C PTPRS 459 80 Tumor Type:overall 0.65 -0.12 1.40 1319.17 1.00 3164 442 63 17 FALSE 1.01
colorectal cancer KRAS_G12C SMARCA4 37 40 Metastasis -1.72 -4.66 0.40 1275.59 1.00 808 36 39 1 FALSE 0.72
colorectal cancer KRAS_G12C SMARCA4 29 129 Primary -2.64 -6.80 -0.33 1303.11 1.00 1214 29 129 0 FALSE 0.97
non-small cell lung cancer KRAS_G12C SMARCA4 167 149 Metastasis 0.27 -0.14 0.70 1403.38 1.00 1099 144 126 23 FALSE 0.66
non-small cell lung cancer KRAS_G12C SMARCA4 292 164 Primary 0.11 -0.34 0.49 1232.69 1.00 1876 270 142 22 FALSE 0.22
colorectal cancer KRAS_G12C SMARCA4 66 169 Tumor Type:overall -2.10 -5.35 0.34 1504.95 1.00 2022 65 168 1 FALSE 0.84
non-small cell lung cancer KRAS_G12C SMARCA4 459 313 Tumor Type:overall 0.18 -0.61 0.85 1490.89 1.00 2975 414 268 45 FALSE 0.20
colorectal cancer KRAS_G12C PTPRT 39 58 Metastasis 0.45 -0.62 1.44 1408.32 1.00 790 34 53 5 FALSE 0.40
colorectal cancer KRAS_G12C PTPRT 29 127 Primary -0.57 -2.29 0.65 1398.72 1.00 1202 28 126 1 FALSE 0.35
non-small cell lung cancer KRAS_G12C PTPRT 168 150 Metastasis 0.08 -0.32 0.45 1190.58 1.00 1113 149 131 19 FALSE 0.16
non-small cell lung cancer KRAS_G12C PTPRT 289 201 Primary 0.08 -0.29 0.44 997.33 1.00 1867 262 174 27 FALSE 0.18
colorectal cancer KRAS_G12C PTPRT 68 185 Tumor Type:overall -0.05 -1.88 1.56 1448.18 1.00 1992 62 179 6 FALSE 0.02
non-small cell lung cancer KRAS_G12C PTPRT 457 351 Tumor Type:overall 0.07 -0.42 0.53 1363.54 1.00 2980 411 305 46 FALSE 0.10
colorectal cancer KRAS_G12C HGF 37 22 Metastasis 0.16 -1.64 1.70 1540.02 1.00 821 35 20 2 FALSE 0.07
colorectal cancer KRAS_G12C HGF 29 34 Primary -0.72 -4.70 1.30 1287.04 1.00 1282 29 34 0 FALSE 0.18
non-small cell lung cancer KRAS_G12C HGF 167 72 Metastasis -0.37 -1.47 0.42 968.19 1.00 1149 163 68 4 FALSE 0.35
non-small cell lung cancer KRAS_G12C HGF 290 119 Primary 0.34 -0.16 0.84 176.96 1.02 1923 267 96 23 FALSE 0.69
colorectal cancer KRAS_G12C HGF 66 56 Tumor Type:overall -0.24 -3.02 1.78 1338.15 1.00 2103 64 54 2 FALSE 0.07
non-small cell lung cancer KRAS_G12C HGF 457 191 Tumor Type:overall -0.01 -1.15 0.93 1376.21 1.00 3072 430 164 27 FALSE 0.00
colorectal cancer KRAS_G12C BLM 37 14 Metastasis -4.86 -12.31 -0.13 1148.38 1.00 831 37 14 0 TRUE 0.89
colorectal cancer KRAS_G12C BLM 29 56 Primary -4.99 -12.64 -0.35 1277.16 1.00 1260 29 56 0 TRUE 0.91
colorectal cancer KRAS_G12C BLM 66 70 Tumor Type:overall -4.72 -12.01 0.10 1114.24 1.00 2091 66 70 0 TRUE 0.91
colorectal cancer KRAS_G12C PIK3CA 45 151 Metastasis -0.55 -1.51 0.26 1341.69 1.00 771 41 147 4 TRUE 0.65
colorectal cancer KRAS_G12C PIK3CA 32 360 Primary -0.12 -0.94 0.65 1547.55 1.00 1160 24 352 8 TRUE 0.11
non-small cell lung cancer KRAS_G12C PIK3CA 171 80 Metastasis -0.10 -0.64 0.37 1134.59 1.00 1192 162 71 9 TRUE 0.16
non-small cell lung cancer KRAS_G12C PIK3CA 301 162 Primary -0.09 -0.53 0.34 1105.96 1.00 1936 282 143 19 TRUE 0.18
colorectal cancer KRAS_G12C PIK3CA 77 511 Tumor Type:overall -0.31 -1.73 1.06 1204.44 1.00 1931 65 499 12 TRUE 0.18
non-small cell lung cancer KRAS_G12C PIK3CA 472 242 Tumor Type:overall -0.09 -0.65 0.54 871.21 1.00 3128 444 214 28 TRUE 0.09
non-small cell lung cancer KRAS_G12C GATA3 166 26 Metastasis 0.83 0.21 1.43 1167.21 1.01 1198 159 19 7 FALSE 2.35
non-small cell lung cancer KRAS_G12C GATA3 289 40 Primary 0.79 0.24 1.30 1337.78 1.00 1981 280 31 9 FALSE 2.65
non-small cell lung cancer KRAS_G12C GATA3 455 66 Tumor Type:overall 0.82 0.20 1.43 1045.74 1.00 3179 439 50 16 FALSE 2.07
colorectal cancer KRAS_G12C ESR1 37 22 Metastasis 0.07 -1.77 1.70 1131.98 1.00 821 35 20 2 TRUE 0.03
colorectal cancer KRAS_G12C ESR1 29 50 Primary -1.04 -5.04 0.82 1277.35 1.00 1265 29 50 0 TRUE 0.32
non-small cell lung cancer KRAS_G12C ESR1 166 17 Metastasis -0.52 -1.83 0.43 857.11 1.01 1201 165 16 1 TRUE 0.44
non-small cell lung cancer KRAS_G12C ESR1 289 39 Primary -0.42 -1.50 0.50 923.62 1.01 1976 285 35 4 TRUE 0.39
colorectal cancer KRAS_G12C ESR1 66 72 Tumor Type:overall -0.45 -3.15 1.51 1318.65 1.00 2086 64 70 2 TRUE 0.16
non-small cell lung cancer KRAS_G12C ESR1 455 56 Tumor Type:overall -0.48 -1.78 0.50 897.38 1.00 3177 450 51 5 TRUE 0.39
colorectal cancer KRAS_G12C ALK 45 37 Metastasis -0.94 -3.09 0.58 1401.56 1.00 873 44 36 1 TRUE 0.50
colorectal cancer KRAS_G12C ALK 32 78 Primary -0.92 -3.03 0.66 1385.72 1.00 1403 31 77 1 TRUE 0.48
non-small cell lung cancer KRAS_G12C ALK 171 67 Metastasis 0.45 -0.02 0.94 1292.04 1.00 1209 160 56 11 TRUE 1.19
non-small cell lung cancer KRAS_G12C ALK 300 102 Primary 0.48 0.03 0.90 1341.86 1.00 1997 280 82 20 TRUE 1.51
colorectal cancer KRAS_G12C ALK 77 115 Tumor Type:overall -0.90 -3.06 0.90 1451.14 1.00 2276 75 113 2 TRUE 0.42
non-small cell lung cancer KRAS_G12C ALK 471 169 Tumor Type:overall 0.48 -0.06 0.98 1411.93 1.00 3206 440 138 31 TRUE 1.00
colorectal cancer KRAS_G12C RNF43 37 64 Metastasis -2.35 -6.17 -0.32 1444.82 1.00 791 37 64 0 TRUE 0.86
colorectal cancer KRAS_G12C RNF43 29 203 Primary -1.42 -3.37 0.07 1467.94 1.00 1165 27 201 2 TRUE 1.03
colorectal cancer KRAS_G12C RNF43 66 267 Tumor Type:overall -1.79 -4.47 0.29 1566.97 1.00 1956 64 265 2 TRUE 0.86
non-small cell lung cancer KRAS_G12C U2AF1 166 30 Metastasis 0.53 -0.11 1.12 1300.89 1.00 1193 160 24 6 FALSE 1.01
non-small cell lung cancer KRAS_G12C U2AF1 289 48 Primary 0.51 -0.15 1.06 1009.74 1.00 1971 280 39 9 FALSE 1.02
non-small cell lung cancer KRAS_G12C U2AF1 455 78 Tumor Type:overall 0.52 -0.21 1.16 1374.65 1.00 3164 440 63 15 FALSE 0.86
colorectal cancer KRAS_G12C LATS1 37 15 Metastasis -4.74 -12.19 0.07 1070.81 1.00 827 37 15 0 FALSE 0.87
colorectal cancer KRAS_G12C LATS1 29 40 Primary -4.74 -11.99 -0.16 1051.15 1.00 1277 29 40 0 FALSE 0.90
non-small cell lung cancer KRAS_G12C LATS1 166 28 Metastasis -0.98 -2.20 0.06 524.06 1.00 1190 164 26 2 FALSE 1.00
non-small cell lung cancer KRAS_G12C LATS1 289 40 Primary -1.02 -2.21 0.01 584.23 1.00 1972 287 38 2 FALSE 1.14
colorectal cancer KRAS_G12C LATS1 66 55 Tumor Type:overall -4.63 -11.78 0.18 1051.75 1.00 2104 66 55 0 FALSE 0.87
non-small cell lung cancer KRAS_G12C LATS1 455 68 Tumor Type:overall -0.99 -2.24 0.09 621.96 1.00 3162 451 64 4 FALSE 1.00
colorectal cancer KRAS_G12C LATS2 37 27 Metastasis -1.15 -3.85 0.88 1257.25 1.00 815 36 26 1 FALSE 0.46
colorectal cancer KRAS_G12C LATS2 29 43 Primary -1.59 -4.86 0.58 1297.50 1.00 1272 29 43 0 FALSE 0.57
non-small cell lung cancer KRAS_G12C LATS2 166 23 Metastasis -0.14 -1.74 0.80 892.01 1.00 1194 165 22 1 FALSE 0.08
non-small cell lung cancer KRAS_G12C LATS2 290 38 Primary 0.27 -0.52 1.06 857.32 1.00 1981 282 30 8 FALSE 0.30
colorectal cancer KRAS_G12C LATS2 66 70 Tumor Type:overall -1.35 -4.38 0.82 1412.91 1.00 2087 65 69 1 FALSE 0.51
non-small cell lung cancer KRAS_G12C LATS2 456 61 Tumor Type:overall 0.08 -1.11 1.10 1172.07 1.00 3175 447 52 9 FALSE 0.05
colorectal cancer KRAS_G12C PTEN 45 43 Metastasis -0.48 -2.13 0.88 1422.60 1.00 873 43 41 2 TRUE 0.28
colorectal cancer KRAS_G12C PTEN 32 142 Primary -1.07 -2.88 0.30 1478.28 1.00 1364 31 141 1 TRUE 0.73
non-small cell lung cancer KRAS_G12C PTEN 171 51 Metastasis -0.64 -1.42 0.07 939.47 1.00 1215 167 47 4 TRUE 1.04
non-small cell lung cancer KRAS_G12C PTEN 300 85 Primary -0.66 -1.41 0.00 942.09 1.00 1999 294 79 6 TRUE 1.22
colorectal cancer KRAS_G12C PTEN 77 185 Tumor Type:overall -0.74 -2.68 1.28 1544.29 1.00 2237 74 182 3 TRUE 0.33
non-small cell lung cancer KRAS_G12C PTEN 471 136 Tumor Type:overall -0.64 -1.40 0.07 989.99 1.00 3214 461 126 10 TRUE 1.05
colorectal cancer KRAS_G12C BCOR 37 18 Metastasis -2.11 -6.72 0.50 1354.01 1.00 824 37 18 0 FALSE 0.60
colorectal cancer KRAS_G12C BCOR 29 94 Primary -1.43 -4.12 0.48 1403.83 1.00 1235 28 93 1 FALSE 0.63
non-small cell lung cancer KRAS_G12C BCOR 168 54 Metastasis 0.31 -0.24 0.77 215.40 1.04 1173 159 45 9 FALSE 0.62
non-small cell lung cancer KRAS_G12C BCOR 291 80 Primary 0.27 -0.29 0.74 70.55 1.06 1946 279 68 12 FALSE 0.54
colorectal cancer KRAS_G12C BCOR 66 112 Tumor Type:overall -1.69 -5.14 0.90 1329.81 1.00 2059 65 111 1 FALSE 0.55
non-small cell lung cancer KRAS_G12C BCOR 459 134 Tumor Type:overall 0.30 -0.28 0.82 208.18 1.03 3119 438 113 21 FALSE 0.48
colorectal cancer KRAS_G12C CTNNB1 45 44 Metastasis 0.69 -0.40 1.66 1573.39 1.00 870 40 39 5 TRUE 0.70
colorectal cancer KRAS_G12C CTNNB1 32 119 Primary -0.63 -2.76 0.76 1545.08 1.00 1354 31 118 1 TRUE 0.32
non-small cell lung cancer KRAS_G12C CTNNB1 172 55 Metastasis -0.44 -1.41 0.35 127.49 1.02 1211 166 49 6 TRUE 0.52
non-small cell lung cancer KRAS_G12C CTNNB1 300 66 Primary -0.65 -1.47 0.08 182.60 1.02 2013 296 62 4 TRUE 0.89
colorectal cancer KRAS_G12C CTNNB1 77 163 Tumor Type:overall 0.05 -1.99 1.94 1499.10 1.00 2224 71 157 6 TRUE 0.02
non-small cell lung cancer KRAS_G12C CTNNB1 472 121 Tumor Type:overall -0.55 -1.47 0.36 236.38 1.01 3224 462 111 10 TRUE 0.58
colorectal cancer KRAS_G12C ARID1A 37 73 Metastasis -0.50 -1.99 0.70 1524.39 1.00 793 34 70 3 TRUE 0.34
colorectal cancer KRAS_G12C ARID1A 29 242 Primary -1.47 -3.26 -0.17 1492.33 1.00 1144 28 241 1 TRUE 1.18
non-small cell lung cancer KRAS_G12C ARID1A 168 129 Metastasis 0.01 -0.59 0.49 1311.89 1.00 1113 154 115 14 TRUE 0.02
non-small cell lung cancer KRAS_G12C ARID1A 293 155 Primary 0.34 -0.08 0.75 1397.21 1.00 1889 265 127 28 TRUE 0.96
colorectal cancer KRAS_G12C ARID1A 66 315 Tumor Type:overall -0.93 -2.81 1.09 1199.04 1.00 1937 62 311 4 TRUE 0.47
non-small cell lung cancer KRAS_G12C ARID1A 461 284 Tumor Type:overall 0.17 -0.62 1.12 1534.60 1.00 3002 419 242 42 TRUE 0.17
colorectal cancer KRAS_G12C PIK3R1 37 27 Metastasis -0.16 -1.97 1.45 1027.07 1.00 821 35 25 2 TRUE 0.07
colorectal cancer KRAS_G12C PIK3R1 29 89 Primary -1.72 -5.77 0.37 1434.42 1.00 1236 29 89 0 TRUE 0.55
non-small cell lung cancer KRAS_G12C PIK3R1 167 12 Metastasis 0.33 -0.89 1.29 1214.01 1.00 1206 165 10 2 TRUE 0.26
non-small cell lung cancer KRAS_G12C PIK3R1 289 43 Primary 0.44 -0.36 1.10 1408.55 1.00 1975 281 35 8 TRUE 0.62
colorectal cancer KRAS_G12C PIK3R1 66 116 Tumor Type:overall -0.90 -4.00 1.45 1409.19 1.00 2057 64 114 2 TRUE 0.30
non-small cell lung cancer KRAS_G12C PIK3R1 456 55 Tumor Type:overall 0.39 -0.82 1.62 1424.50 1.00 3181 446 45 10 TRUE 0.29
colorectal cancer KRAS_G12C IKZF1 37 24 Metastasis -0.44 -2.43 1.25 1199.44 1.00 820 36 23 1 TRUE 0.19
colorectal cancer KRAS_G12C IKZF1 29 62 Primary -0.54 -2.60 1.06 1333.02 1.00 1254 28 61 1 TRUE 0.25
non-small cell lung cancer KRAS_G12C IKZF1 166 36 Metastasis 0.36 -0.30 1.08 618.10 1.01 1188 158 28 8 TRUE 0.49
non-small cell lung cancer KRAS_G12C IKZF1 289 46 Primary 0.11 -0.74 0.76 1103.55 1.00 1970 284 41 5 TRUE 0.11
colorectal cancer KRAS_G12C IKZF1 66 86 Tumor Type:overall -0.50 -2.71 1.39 1318.61 1.00 2074 64 84 2 TRUE 0.20
non-small cell lung cancer KRAS_G12C IKZF1 455 82 Tumor Type:overall 0.23 -0.63 1.02 1063.10 1.00 3158 442 69 13 TRUE 0.23
colorectal cancer KRAS_G12C TERT 37 27 Metastasis 0.03 -1.71 1.31 1593.79 1.00 819 36 26 1 TRUE 0.01
colorectal cancer KRAS_G12C TERT 29 71 Primary 0.41 -0.92 1.53 1552.49 1.00 1251 26 68 3 TRUE 0.29
non-small cell lung cancer KRAS_G12C TERT 168 61 Metastasis 0.65 0.22 1.12 1100.51 1.00 1172 154 47 14 TRUE 2.29
non-small cell lung cancer KRAS_G12C TERT 290 105 Primary 0.60 0.19 0.99 1035.15 1.00 1927 270 85 20 TRUE 2.42
colorectal cancer KRAS_G12C TERT 66 98 Tumor Type:overall 0.19 -1.69 1.75 1541.06 1.00 2070 62 94 4 TRUE 0.08
non-small cell lung cancer KRAS_G12C TERT 458 166 Tumor Type:overall 0.62 0.10 1.17 1033.27 1.01 3099 424 132 34 TRUE 1.44
colorectal cancer KRAS_G12C FAT1 37 62 Metastasis -5.70 -12.05 -1.44 1046.57 1.00 800 37 62 0 FALSE 1.36
colorectal cancer KRAS_G12C FAT1 29 165 Primary -5.69 -12.38 -1.73 1072.33 1.00 1202 29 165 0 FALSE 1.38
non-small cell lung cancer KRAS_G12C FAT1 166 123 Metastasis 0.29 -0.10 0.65 1391.49 1.00 1118 148 105 18 FALSE 0.88
non-small cell lung cancer KRAS_G12C FAT1 293 182 Primary 0.30 -0.07 0.65 1298.63 1.00 1878 263 152 30 FALSE 1.05
colorectal cancer KRAS_G12C FAT1 66 227 Tumor Type:overall -5.56 -11.69 -1.47 1135.16 1.00 2002 66 227 0 FALSE 1.36
non-small cell lung cancer KRAS_G12C FAT1 459 305 Tumor Type:overall 0.30 -0.17 0.71 1428.25 1.00 2996 411 257 48 FALSE 0.65
colorectal cancer KRAS_G12C FGFR4 29 46 Primary -4.98 -14.10 0.28 1194.78 1.00 1271 29 46 0 TRUE 0.65
colorectal cancer KRAS_G12C FGFR4 29 46 Tumor Type:overall -3.66 -11.46 3.24 1141.27 1.00 1271 29 46 0 TRUE 0.50
colorectal cancer KRAS_G12C CIC 37 37 Metastasis -0.49 -2.45 1.06 1467.29 1.00 812 35 35 2 TRUE 0.23
colorectal cancer KRAS_G12C CIC 29 100 Primary -1.87 -6.15 0.18 1202.55 1.00 1235 29 100 0 TRUE 0.54
non-small cell lung cancer KRAS_G12C CIC 170 53 Metastasis 0.37 -0.40 1.06 1178.69 1.00 1178 160 43 10 TRUE 0.50
non-small cell lung cancer KRAS_G12C CIC 289 39 Primary -0.32 -1.50 0.50 1537.80 1.00 1976 286 36 3 TRUE 0.27
colorectal cancer KRAS_G12C CIC 66 137 Tumor Type:overall -1.08 -4.04 1.19 1009.28 1.00 2047 64 135 2 TRUE 0.38
non-small cell lung cancer KRAS_G12C CIC 459 92 Tumor Type:overall 0.01 -1.46 1.34 1504.45 1.00 3154 446 79 13 TRUE 0.01
colorectal cancer KRAS_G12C KDM6A 37 13 Metastasis -4.69 -11.32 -0.13 1351.94 1.00 829 37 13 0 FALSE 0.92
colorectal cancer KRAS_G12C KDM6A 29 49 Primary -4.74 -11.49 -0.21 1403.98 1.00 1266 29 49 0 FALSE 0.94
non-small cell lung cancer KRAS_G12C KDM6A 166 23 Metastasis -0.29 -1.25 0.58 694.88 1.00 1197 163 20 3 FALSE 0.28
non-small cell lung cancer KRAS_G12C KDM6A 289 38 Primary -0.38 -1.31 0.43 669.90 1.01 1977 286 35 3 FALSE 0.40
colorectal cancer KRAS_G12C KDM6A 66 62 Tumor Type:overall -4.58 -11.17 -0.15 1341.83 1.00 2095 66 62 0 FALSE 0.94
non-small cell lung cancer KRAS_G12C KDM6A 455 61 Tumor Type:overall -0.32 -1.30 0.55 669.09 1.01 3174 449 55 6 FALSE 0.29
colorectal cancer KRAS_G12C NCOR1 37 37 Metastasis -5.25 -12.32 -0.77 717.93 1.01 808 37 37 0 FALSE 1.06
colorectal cancer KRAS_G12C NCOR1 29 98 Primary -5.25 -12.36 -0.99 810.79 1.01 1236 29 98 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C NCOR1 168 52 Metastasis 0.26 -0.40 0.90 1034.00 1.00 1179 159 43 9 FALSE 0.36
non-small cell lung cancer KRAS_G12C NCOR1 289 52 Primary 0.02 -0.74 0.65 1278.92 1.00 1965 283 46 6 FALSE 0.02
colorectal cancer KRAS_G12C NCOR1 66 135 Tumor Type:overall -5.12 -11.99 -0.71 705.34 1.01 2044 66 135 0 FALSE 1.07
non-small cell lung cancer KRAS_G12C NCOR1 457 104 Tumor Type:overall 0.16 -0.74 1.16 1391.44 1.00 3144 442 89 15 FALSE 0.12
colorectal cancer KRAS_G12C POLE 37 28 Metastasis -5.35 -12.71 -0.82 1525.84 1.00 814 37 28 0 TRUE 1.05
colorectal cancer KRAS_G12C POLE 29 113 Primary -5.40 -12.47 -1.05 1451.39 1.00 1226 29 113 0 TRUE 1.05
non-small cell lung cancer KRAS_G12C POLE 166 59 Metastasis 0.77 0.22 1.35 1429.89 1.01 1174 151 44 15 TRUE 2.30
non-small cell lung cancer KRAS_G12C POLE 290 77 Primary 0.59 0.02 1.06 1515.79 1.00 1952 276 63 14 TRUE 1.71
colorectal cancer KRAS_G12C POLE 66 141 Tumor Type:overall -5.18 -12.17 -0.79 1555.72 1.00 2040 66 141 0 TRUE 1.08
non-small cell lung cancer KRAS_G12C POLE 456 136 Tumor Type:overall 0.69 0.05 1.39 1369.49 1.00 3126 427 107 29 TRUE 1.29
non-small cell lung cancer KRAS_G12C CUL3 166 26 Metastasis 0.45 -0.36 1.09 618.49 1.01 1195 162 22 4 FALSE 0.64
non-small cell lung cancer KRAS_G12C CUL3 290 51 Primary 0.52 -0.09 1.08 400.45 1.01 1975 279 40 11 FALSE 1.03
non-small cell lung cancer KRAS_G12C CUL3 456 77 Tumor Type:overall 0.48 -0.23 1.16 755.90 1.01 3170 441 62 15 FALSE 0.71
colorectal cancer KRAS_G12C ABL1 45 17 Metastasis -4.73 -11.41 -0.18 770.09 1.00 893 45 17 0 TRUE 0.99
colorectal cancer KRAS_G12C ABL1 32 56 Primary -4.75 -11.36 -0.32 827.73 1.00 1416 32 56 0 TRUE 0.99
colorectal cancer KRAS_G12C ABL1 77 73 Tumor Type:overall -4.62 -11.25 -0.20 770.68 1.00 2309 77 73 0 TRUE 0.97
colorectal cancer KRAS_G12C FOXP1 37 15 Metastasis -1.74 -5.69 0.77 823.31 1.00 826 37 15 0 FALSE 0.51
colorectal cancer KRAS_G12C FOXP1 29 55 Primary -1.10 -3.95 0.95 1133.19 1.00 1263 28 54 1 FALSE 0.43
colorectal cancer KRAS_G12C FOXP1 66 70 Tumor Type:overall -1.38 -4.67 1.19 989.29 1.00 2089 65 69 1 FALSE 0.46
colorectal cancer KRAS_G12C NOTCH2 37 18 Metastasis -4.68 -11.68 -0.13 801.22 1.00 825 37 18 0 TRUE 0.94
colorectal cancer KRAS_G12C NOTCH2 29 55 Primary -4.76 -11.64 -0.32 922.37 1.00 1264 29 55 0 TRUE 0.97
non-small cell lung cancer KRAS_G12C NOTCH2 166 40 Metastasis -0.12 -0.81 0.57 702.65 1.00 1185 161 35 5 TRUE 0.14
non-small cell lung cancer KRAS_G12C NOTCH2 289 75 Primary -0.16 -0.81 0.45 699.01 1.00 1949 281 67 8 TRUE 0.20
colorectal cancer KRAS_G12C NOTCH2 66 73 Tumor Type:overall -4.60 -11.36 -0.14 851.03 1.00 2089 66 73 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C NOTCH2 455 115 Tumor Type:overall -0.14 -0.88 0.57 866.16 1.00 3134 442 102 13 TRUE 0.13
non-small cell lung cancer KRAS_G12C DDR2 166 45 Metastasis 0.20 -0.49 0.78 1347.52 1.00 1177 160 39 6 TRUE 0.26
non-small cell lung cancer KRAS_G12C DDR2 289 53 Primary 0.24 -0.40 0.86 968.48 1.00 1965 280 44 9 TRUE 0.36
non-small cell lung cancer KRAS_G12C DDR2 455 98 Tumor Type:overall 0.23 -0.53 1.01 1240.22 1.00 3142 440 83 15 TRUE 0.26
colorectal cancer KRAS_G12C TGFBR2 37 26 Metastasis -1.31 -4.37 0.82 1243.79 1.00 816 36 25 1 TRUE 0.49
colorectal cancer KRAS_G12C TGFBR2 29 88 Primary -2.26 -6.34 0.08 1405.05 1.00 1230 29 88 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C TGFBR2 167 27 Metastasis 0.66 -0.08 1.33 1142.19 1.00 1196 161 21 6 TRUE 1.19
non-small cell lung cancer KRAS_G12C TGFBR2 289 29 Primary 0.60 -0.18 1.26 1073.32 1.00 1988 283 23 6 TRUE 1.01
colorectal cancer KRAS_G12C TGFBR2 66 114 Tumor Type:overall -1.73 -5.09 0.75 1230.22 1.00 2046 65 113 1 TRUE 0.63
non-small cell lung cancer KRAS_G12C TGFBR2 456 56 Tumor Type:overall 0.63 -0.24 1.38 1188.35 1.00 3184 444 44 12 TRUE 0.89
colorectal cancer KRAS_G12C SMO 45 19 Metastasis -0.98 -3.93 1.03 1486.31 1.00 890 44 18 1 TRUE 0.35
colorectal cancer KRAS_G12C SMO 32 52 Primary -1.83 -6.22 0.53 1375.63 1.00 1420 32 52 0 TRUE 0.51
non-small cell lung cancer KRAS_G12C SMO 171 29 Metastasis 0.38 -0.44 0.90 6.42 1.15 1237 166 24 5 TRUE 0.58
non-small cell lung cancer KRAS_G12C SMO 300 46 Primary 0.36 -0.42 0.79 4.45 1.22 2036 293 39 7 TRUE 0.54
colorectal cancer KRAS_G12C SMO 77 71 Tumor Type:overall -1.36 -4.84 1.04 1407.90 1.00 2310 76 70 1 TRUE 0.43
non-small cell lung cancer KRAS_G12C SMO 471 75 Tumor Type:overall 0.36 -0.47 0.86 6.40 1.16 3273 459 63 12 TRUE 0.49
colorectal cancer KRAS_G12C RPS6KA4 29 53 Primary -0.64 -3.66 1.29 1467.06 1.00 1263 28 52 1 FALSE 0.21
colorectal cancer KRAS_G12C RPS6KA4 29 53 Tumor Type:overall -0.44 -5.18 4.49 1438.10 1.00 1263 28 52 1 FALSE 0.07
colorectal cancer KRAS_G12C KMT2A 37 37 Metastasis -0.99 -3.19 0.58 1607.18 1.00 812 36 36 1 FALSE 0.51
colorectal cancer KRAS_G12C KMT2A 29 111 Primary -1.13 -3.16 0.37 1489.59 1.00 1229 28 110 1 FALSE 0.65
non-small cell lung cancer KRAS_G12C KMT2A 166 53 Metastasis 0.04 -0.60 0.65 523.48 1.00 1173 160 47 6 FALSE 0.05
non-small cell lung cancer KRAS_G12C KMT2A 289 61 Primary 0.13 -0.44 0.74 383.52 1.01 1961 279 51 10 FALSE 0.17
colorectal cancer KRAS_G12C KMT2A 66 148 Tumor Type:overall -1.02 -3.30 0.88 1626.61 1.00 2041 64 146 2 FALSE 0.45
non-small cell lung cancer KRAS_G12C KMT2A 455 114 Tumor Type:overall 0.10 -0.58 0.83 856.70 1.00 3134 439 98 16 FALSE 0.10
colorectal cancer KRAS_G12C JAK3 45 22 Metastasis -1.00 -4.72 1.00 1206.15 1.00 888 45 22 0 TRUE 0.29
colorectal cancer KRAS_G12C JAK3 32 41 Primary 0.13 -1.84 1.60 1028.88 1.00 1429 30 39 2 TRUE 0.05
non-small cell lung cancer KRAS_G12C JAK3 172 23 Metastasis 0.72 -0.09 1.63 781.63 1.00 1244 165 16 7 TRUE 0.98
non-small cell lung cancer KRAS_G12C JAK3 300 60 Primary 0.27 -0.52 0.88 1393.92 1.00 2023 292 52 8 TRUE 0.34
colorectal cancer KRAS_G12C JAK3 77 63 Tumor Type:overall -0.39 -3.14 1.61 1228.35 1.00 2317 75 61 2 TRUE 0.13
non-small cell lung cancer KRAS_G12C JAK3 472 83 Tumor Type:overall 0.50 -0.61 1.64 1364.82 1.00 3267 457 68 15 TRUE 0.41
non-small cell lung cancer KRAS_G12C PAK7 166 61 Metastasis -0.05 -0.80 0.50 288.28 1.00 1166 159 54 7 FALSE 0.06
non-small cell lung cancer KRAS_G12C PAK7 289 72 Primary -0.05 -0.69 0.50 126.47 1.02 1952 280 63 9 FALSE 0.06
non-small cell lung cancer KRAS_G12C PAK7 455 133 Tumor Type:overall -0.04 -0.85 0.63 388.83 1.01 3118 439 117 16 FALSE 0.04
non-small cell lung cancer KRAS_G12C STAG2 166 43 Metastasis 0.14 -0.61 0.74 1158.57 1.00 1182 161 38 5 TRUE 0.17
non-small cell lung cancer KRAS_G12C STAG2 289 59 Primary 0.22 -0.42 0.80 1156.01 1.00 1962 279 49 10 TRUE 0.32
non-small cell lung cancer KRAS_G12C STAG2 455 102 Tumor Type:overall 0.18 -0.58 0.82 1356.59 1.00 3144 440 87 15 TRUE 0.21
colorectal cancer KRAS_G12C BRCA2 37 48 Metastasis -0.81 -2.81 0.67 1484.58 1.00 805 35 46 2 TRUE 0.43
colorectal cancer KRAS_G12C BRCA2 29 142 Primary -2.21 -6.09 -0.20 1274.35 1.00 1223 29 142 0 TRUE 0.79
non-small cell lung cancer KRAS_G12C BRCA2 166 67 Metastasis 0.12 -0.52 0.71 446.82 1.01 1166 157 58 9 TRUE 0.15
non-small cell lung cancer KRAS_G12C BRCA2 289 68 Primary 0.11 -0.50 0.73 365.35 1.01 1955 279 58 10 TRUE 0.13
colorectal cancer KRAS_G12C BRCA2 66 190 Tumor Type:overall -1.44 -4.37 0.91 1513.04 1.00 2028 64 188 2 TRUE 0.58
non-small cell lung cancer KRAS_G12C BRCA2 455 135 Tumor Type:overall 0.12 -0.68 1.02 1075.43 1.00 3121 436 116 19 TRUE 0.10
colorectal cancer KRAS_G12C NOTCH3 37 58 Metastasis -5.61 -12.83 -1.32 1252.04 1.00 793 37 58 0 TRUE 1.24
colorectal cancer KRAS_G12C NOTCH3 29 142 Primary -5.64 -12.85 -1.43 1298.11 1.00 1202 29 142 0 TRUE 1.27
non-small cell lung cancer KRAS_G12C NOTCH3 166 51 Metastasis 0.20 -0.49 0.95 1001.34 1.00 1177 156 41 10 TRUE 0.23
non-small cell lung cancer KRAS_G12C NOTCH3 289 77 Primary -0.20 -0.98 0.43 1200.68 1.00 1945 283 71 6 TRUE 0.23
colorectal cancer KRAS_G12C NOTCH3 66 200 Tumor Type:overall -5.46 -12.42 -1.17 1230.74 1.00 1995 66 200 0 TRUE 1.23
non-small cell lung cancer KRAS_G12C NOTCH3 455 128 Tumor Type:overall 0.00 -0.79 0.78 1382.91 1.00 3122 439 112 16 TRUE 0.00
colorectal cancer KRAS_G12C NOTCH4 37 33 Metastasis -0.42 -2.19 0.88 1595.06 1.00 810 36 32 1 TRUE 0.22
colorectal cancer KRAS_G12C NOTCH4 29 89 Primary -0.26 -1.82 0.94 1608.33 1.00 1239 27 87 2 TRUE 0.15
non-small cell lung cancer KRAS_G12C NOTCH4 166 55 Metastasis -0.23 -0.99 0.29 53.72 1.05 1168 161 50 5 TRUE 0.33
non-small cell lung cancer KRAS_G12C NOTCH4 289 84 Primary -0.20 -0.84 0.26 64.98 1.04 1938 280 75 9 TRUE 0.35
colorectal cancer KRAS_G12C NOTCH4 66 122 Tumor Type:overall -0.32 -2.08 1.30 1668.19 1.00 2049 63 119 3 TRUE 0.15
non-small cell lung cancer KRAS_G12C NOTCH4 455 139 Tumor Type:overall -0.21 -0.91 0.31 185.64 1.04 3106 441 125 14 TRUE 0.29
colorectal cancer KRAS_G12C FGFR3 45 14 Metastasis -4.91 -12.52 -0.11 1238.02 1.00 895 45 14 0 TRUE 0.91
colorectal cancer KRAS_G12C FGFR3 32 46 Primary -4.95 -12.42 -0.35 1225.60 1.00 1423 32 46 0 TRUE 0.95
colorectal cancer KRAS_G12C FGFR3 77 60 Tumor Type:overall -4.77 -11.78 -0.20 1203.89 1.00 2318 77 60 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C MAP3K13 166 23 Metastasis -0.75 -2.36 0.33 409.07 1.01 1195 165 22 1 FALSE 0.61
non-small cell lung cancer KRAS_G12C MAP3K13 289 29 Primary -0.64 -2.01 0.36 381.27 1.01 1983 286 26 3 FALSE 0.56
non-small cell lung cancer KRAS_G12C MAP3K13 455 52 Tumor Type:overall -0.69 -2.25 0.44 444.24 1.01 3178 451 48 4 FALSE 0.54
colorectal cancer KRAS_G12C IGF1R 37 22 Metastasis -4.96 -12.00 -0.53 429.57 1.01 823 37 22 0 TRUE 1.01
colorectal cancer KRAS_G12C IGF1R 29 58 Primary -4.97 -11.85 -0.61 399.34 1.01 1260 29 58 0 TRUE 1.03
non-small cell lung cancer KRAS_G12C IGF1R 166 26 Metastasis 0.74 -0.03 1.52 24.54 1.10 1198 159 19 7 TRUE 1.06
non-small cell lung cancer KRAS_G12C IGF1R 289 28 Primary 0.56 -0.18 1.28 52.52 1.05 1986 284 23 5 TRUE 0.75
colorectal cancer KRAS_G12C IGF1R 66 80 Tumor Type:overall -4.85 -11.52 -0.41 351.85 1.01 2083 66 80 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C IGF1R 455 54 Tumor Type:overall 0.65 -0.23 1.55 57.44 1.05 3184 443 42 12 TRUE 0.66
non-small cell lung cancer KRAS_G12C KEAP1 169 234 Metastasis 0.55 0.21 0.89 1446.77 1.00 1030 127 192 42 FALSE 3.01
non-small cell lung cancer KRAS_G12C KEAP1 291 304 Primary 0.48 0.20 0.77 1572.24 1.00 1771 237 250 54 FALSE 3.12
non-small cell lung cancer KRAS_G12C KEAP1 460 538 Tumor Type:overall 0.53 0.03 1.03 1394.76 1.00 2801 364 442 96 FALSE 1.42
colorectal cancer KRAS_G12C KDM5C 37 14 Metastasis -1.72 -5.72 0.76 1417.59 1.00 828 37 14 0 FALSE 0.49
colorectal cancer KRAS_G12C KDM5C 29 55 Primary -1.05 -4.07 0.94 1571.03 1.00 1269 28 54 1 FALSE 0.39
non-small cell lung cancer KRAS_G12C KDM5C 166 41 Metastasis -0.01 -0.91 0.61 104.28 1.04 1179 163 38 3 FALSE 0.01
non-small cell lung cancer KRAS_G12C KDM5C 290 65 Primary 0.20 -0.44 0.76 613.67 1.01 1959 278 53 12 FALSE 0.30
colorectal cancer KRAS_G12C KDM5C 66 69 Tumor Type:overall -1.33 -4.79 1.21 1312.11 1.00 2097 65 68 1 FALSE 0.42
non-small cell lung cancer KRAS_G12C KDM5C 456 106 Tumor Type:overall 0.10 -0.69 0.75 391.58 1.01 3138 441 91 15 FALSE 0.10
non-small cell lung cancer KRAS_G12C CDKN2A 174 92 Metastasis 0.41 -0.23 0.97 1143.80 1.00 1190 156 74 18 TRUE 0.75
non-small cell lung cancer KRAS_G12C CDKN2A 301 184 Primary -0.62 -1.28 -0.07 1393.50 1.00 1911 289 172 12 TRUE 1.34
non-small cell lung cancer KRAS_G12C CDKN2A 475 276 Tumor Type:overall -0.11 -1.42 1.22 1484.55 1.00 3101 445 246 30 TRUE 0.06
colorectal cancer KRAS_G12C EPHB1 37 25 Metastasis -5.05 -11.90 -0.46 717.74 1.00 816 37 25 0 FALSE 1.01
colorectal cancer KRAS_G12C EPHB1 29 57 Primary -5.06 -11.59 -0.64 588.97 1.00 1258 29 57 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C EPHB1 166 59 Metastasis -0.08 -0.73 0.44 1024.00 1.00 1166 160 53 6 FALSE 0.10
non-small cell lung cancer KRAS_G12C EPHB1 290 99 Primary -0.04 -0.56 0.46 850.04 1.00 1933 277 86 13 FALSE 0.05
colorectal cancer KRAS_G12C EPHB1 66 82 Tumor Type:overall -5.00 -11.67 -0.51 618.96 1.00 2074 66 82 0 FALSE 1.03
non-small cell lung cancer KRAS_G12C EPHB1 456 158 Tumor Type:overall -0.06 -0.71 0.48 736.82 1.00 3099 437 139 19 FALSE 0.08
colorectal cancer KRAS_G12C IRS2 37 11 Metastasis -0.49 -3.91 1.84 1408.60 1.00 832 36 10 1 FALSE 0.13
colorectal cancer KRAS_G12C IRS2 29 76 Primary -2.39 -7.38 0.26 1417.67 1.00 1244 29 76 0 FALSE 0.60
non-small cell lung cancer KRAS_G12C IRS2 166 36 Metastasis -0.47 -1.39 0.31 326.87 1.01 1184 164 34 2 FALSE 0.49
non-small cell lung cancer KRAS_G12C IRS2 289 48 Primary -0.32 -1.30 0.42 278.21 1.01 1968 283 42 6 FALSE 0.36
colorectal cancer KRAS_G12C IRS2 66 87 Tumor Type:overall -1.30 -5.04 1.96 1446.37 1.00 2076 65 86 1 FALSE 0.35
non-small cell lung cancer KRAS_G12C IRS2 455 84 Tumor Type:overall -0.39 -1.34 0.42 336.92 1.01 3152 447 76 8 FALSE 0.39
colorectal cancer KRAS_G12C FANCA 37 12 Metastasis -4.82 -11.88 -0.10 1317.79 1.00 831 37 12 0 TRUE 0.90
colorectal cancer KRAS_G12C FANCA 29 53 Primary -4.85 -11.70 -0.17 1441.25 1.00 1263 29 53 0 TRUE 0.99
non-small cell lung cancer KRAS_G12C FANCA 166 34 Metastasis -0.01 -0.90 0.78 811.62 1.00 1187 162 30 4 TRUE 0.01
non-small cell lung cancer KRAS_G12C FANCA 289 35 Primary 0.01 -0.86 0.80 1106.87 1.00 1981 284 30 5 TRUE 0.01
colorectal cancer KRAS_G12C FANCA 66 65 Tumor Type:overall -4.62 -11.52 0.04 1378.43 1.00 2094 66 65 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C FANCA 455 69 Tumor Type:overall 0.00 -1.04 1.01 1132.01 1.00 3168 446 60 9 TRUE 0.00
non-small cell lung cancer KRAS_G12C IL7R 166 35 Metastasis -0.14 -0.98 0.55 951.67 1.00 1184 163 32 3 FALSE 0.14
non-small cell lung cancer KRAS_G12C IL7R 290 56 Primary -0.05 -0.76 0.58 910.03 1.00 1969 282 48 8 FALSE 0.05
non-small cell lung cancer KRAS_G12C IL7R 456 91 Tumor Type:overall -0.10 -0.96 0.64 1089.06 1.00 3153 445 80 11 FALSE 0.09
colorectal cancer KRAS_G12C PIK3CB 37 12 Metastasis -1.62 -5.52 0.99 1444.36 1.00 832 37 12 0 FALSE 0.46
colorectal cancer KRAS_G12C PIK3CB 29 56 Primary -0.99 -3.69 0.87 1471.85 1.00 1269 28 55 1 FALSE 0.39
colorectal cancer KRAS_G12C PIK3CB 66 68 Tumor Type:overall -1.27 -4.53 1.29 1306.37 1.00 2101 65 67 1 FALSE 0.41
colorectal cancer KRAS_G12C ERBB3 37 39 Metastasis -0.52 -2.24 0.80 1425.74 1.00 806 36 38 1 TRUE 0.30
colorectal cancer KRAS_G12C ERBB3 29 83 Primary -0.28 -1.83 0.93 1554.07 1.00 1242 27 81 2 TRUE 0.16
colorectal cancer KRAS_G12C ERBB3 66 122 Tumor Type:overall -0.37 -2.13 1.14 1369.97 1.00 2048 63 119 3 TRUE 0.18
colorectal cancer KRAS_G12C SMAD4 45 149 Metastasis -0.06 -0.90 0.67 1434.35 1.00 774 39 143 6 TRUE 0.06
colorectal cancer KRAS_G12C SMAD4 32 211 Primary 0.34 -0.46 1.11 1458.20 1.00 1285 25 204 7 TRUE 0.39
non-small cell lung cancer KRAS_G12C SMAD4 171 49 Metastasis -0.21 -0.94 0.41 1401.58 1.00 1217 167 45 4 TRUE 0.25
non-small cell lung cancer KRAS_G12C SMAD4 300 67 Primary -0.11 -0.79 0.48 1077.55 1.00 2017 291 58 9 TRUE 0.14
colorectal cancer KRAS_G12C SMAD4 77 360 Tumor Type:overall 0.13 -1.25 1.34 1293.80 1.00 2059 64 347 13 TRUE 0.08
non-small cell lung cancer KRAS_G12C SMAD4 471 116 Tumor Type:overall -0.16 -0.92 0.51 1430.35 1.00 3234 458 103 13 TRUE 0.18
colorectal cancer KRAS_G12C ATM 46 71 Metastasis -0.20 -1.50 0.86 1398.86 1.00 854 42 67 4 TRUE 0.12
colorectal cancer KRAS_G12C ATM 32 160 Primary -2.13 -6.14 -0.03 1107.95 1.00 1346 32 160 0 TRUE 0.66
non-small cell lung cancer KRAS_G12C ATM 174 122 Metastasis 1.00 0.55 1.36 1426.40 1.00 1177 146 94 28 TRUE 5.97
non-small cell lung cancer KRAS_G12C ATM 310 166 Primary 1.13 0.80 1.45 1405.26 1.00 1967 259 115 51 TRUE 11.23
colorectal cancer KRAS_G12C ATM 78 231 Tumor Type:overall -1.06 -4.16 1.27 1569.64 1.00 2200 74 227 4 TRUE 0.39
non-small cell lung cancer KRAS_G12C ATM 484 288 Tumor Type:overall 1.07 0.56 1.64 1478.94 1.00 3144 405 209 79 TRUE 4.08
colorectal cancer KRAS_G12C RB1 32 58 Primary -5.29 -14.12 -0.28 231.22 1.01 1421 32 58 0 TRUE 0.69
non-small cell lung cancer KRAS_G12C RB1 171 96 Metastasis -0.83 -1.55 -0.29 106.54 1.03 1173 166 91 5 TRUE 2.31
non-small cell lung cancer KRAS_G12C RB1 300 127 Primary -0.78 -1.34 -0.27 1143.27 1.01 1957 291 118 9 TRUE 2.62
colorectal cancer KRAS_G12C RB1 32 58 Tumor Type:overall -4.01 -11.58 2.96 158.75 1.04 1421 32 58 0 TRUE 0.58
non-small cell lung cancer KRAS_G12C RB1 471 223 Tumor Type:overall -0.80 -1.50 -0.24 1070.64 1.01 3130 457 209 14 TRUE 1.97
colorectal cancer KRAS_G12C KMT2D 37 82 Metastasis -1.87 -4.02 -0.20 1311.20 1.00 785 36 81 1 FALSE 1.28
colorectal cancer KRAS_G12C KMT2D 29 306 Primary -2.12 -4.07 -0.59 1307.93 1.00 1134 28 305 1 FALSE 1.74
non-small cell lung cancer KRAS_G12C KMT2D 168 125 Metastasis 0.02 -0.39 0.46 1307.85 1.00 1127 150 107 18 FALSE 0.03
non-small cell lung cancer KRAS_G12C KMT2D 289 203 Primary -0.09 -0.51 0.28 1098.25 1.00 1854 268 182 21 FALSE 0.19
colorectal cancer KRAS_G12C KMT2D 66 388 Tumor Type:overall -1.94 -4.38 0.17 1499.53 1.00 1919 64 386 2 FALSE 1.08
non-small cell lung cancer KRAS_G12C KMT2D 457 328 Tumor Type:overall -0.03 -0.47 0.44 1423.30 1.00 2981 418 289 39 FALSE 0.05
colorectal cancer KRAS_G12C TSC2 37 25 Metastasis -5.17 -12.54 -0.72 1329.01 1.00 820 37 25 0 TRUE 1.04
colorectal cancer KRAS_G12C TSC2 29 90 Primary -5.17 -12.38 -0.86 1429.66 1.00 1238 29 90 0 TRUE 1.03
non-small cell lung cancer KRAS_G12C TSC2 166 28 Metastasis -1.02 -2.29 0.00 890.74 1.00 1190 165 27 1 TRUE 1.08
non-small cell lung cancer KRAS_G12C TSC2 289 44 Primary -0.96 -2.19 0.06 989.22 1.00 1971 286 41 3 TRUE 1.06
colorectal cancer KRAS_G12C TSC2 66 115 Tumor Type:overall -4.95 -11.63 -0.48 1501.62 1.00 2058 66 115 0 TRUE 1.00
non-small cell lung cancer KRAS_G12C TSC2 455 72 Tumor Type:overall -0.98 -2.29 0.13 1008.35 1.00 3161 451 68 4 TRUE 1.00
colorectal cancer KRAS_G12C APC 63 1010 Metastasis 0.28 -0.28 0.89 1514.89 1.00 274 12 959 51 TRUE 0.47
colorectal cancer KRAS_G12C APC 40 1528 Primary 0.01 -0.58 0.65 1506.22 1.00 530 10 1498 30 TRUE 0.02
non-small cell lung cancer KRAS_G12C APC 171 65 Metastasis -0.24 -0.82 0.36 934.00 1.00 1205 164 58 7 TRUE 0.39
non-small cell lung cancer KRAS_G12C APC 303 92 Primary -0.27 -0.86 0.23 832.17 1.01 1993 294 83 9 TRUE 0.50
colorectal cancer KRAS_G12C APC 103 2538 Tumor Type:overall 0.16 -0.93 1.20 1472.61 1.00 804 22 2457 81 TRUE 0.12
non-small cell lung cancer KRAS_G12C APC 474 157 Tumor Type:overall -0.25 -0.91 0.36 1011.34 1.00 3198 458 141 16 TRUE 0.36
colorectal cancer KRAS_G12C ERBB2 45 32 Metastasis 0.49 -0.70 1.59 1473.10 1.00 884 42 29 3 TRUE 0.38
colorectal cancer KRAS_G12C ERBB2 32 72 Primary 0.26 -1.03 1.34 1336.42 1.00 1399 30 70 2 TRUE 0.18
non-small cell lung cancer KRAS_G12C ERBB2 171 46 Metastasis -3.30 -6.09 -1.51 681.42 1.00 1216 171 46 0 TRUE 2.28
non-small cell lung cancer KRAS_G12C ERBB2 300 83 Primary -3.21 -5.87 -1.46 655.06 1.01 1994 299 82 1 TRUE 2.41
colorectal cancer KRAS_G12C ERBB2 77 104 Tumor Type:overall 0.40 -1.23 1.94 1458.68 1.00 2283 72 99 5 TRUE 0.22
non-small cell lung cancer KRAS_G12C ERBB2 471 129 Tumor Type:overall -3.23 -5.96 -1.44 655.33 1.00 3210 470 128 1 TRUE 2.30
colorectal cancer KRAS_G12C JAK1 37 12 Metastasis -4.60 -11.63 0.06 1038.19 1.00 829 37 12 0 TRUE 0.85
colorectal cancer KRAS_G12C JAK1 29 63 Primary -4.83 -11.91 -0.51 857.23 1.00 1263 29 63 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C JAK1 166 20 Metastasis -0.47 -1.45 0.57 49.16 1.06 1198 164 18 2 TRUE 0.40
non-small cell lung cancer KRAS_G12C JAK1 289 32 Primary -0.50 -1.41 0.47 44.61 1.06 1983 286 29 3 TRUE 0.46
colorectal cancer KRAS_G12C JAK1 66 75 Tumor Type:overall -4.57 -11.43 -0.10 941.25 1.00 2092 66 75 0 TRUE 0.87
non-small cell lung cancer KRAS_G12C JAK1 455 52 Tumor Type:overall -0.49 -1.43 0.60 52.61 1.05 3181 450 47 5 TRUE 0.39
colorectal cancer KRAS_G12C ARID2 37 31 Metastasis -1.38 -4.28 0.53 1222.30 1.00 816 36 30 1 FALSE 0.61
colorectal cancer KRAS_G12C ARID2 29 79 Primary -2.08 -6.06 0.13 1344.67 1.00 1242 29 79 0 FALSE 0.72
non-small cell lung cancer KRAS_G12C ARID2 167 74 Metastasis 0.35 -0.15 0.94 1064.09 1.00 1164 152 59 15 FALSE 0.70
non-small cell lung cancer KRAS_G12C ARID2 289 108 Primary 0.09 -0.52 0.55 836.82 1.00 1920 277 96 12 FALSE 0.14
colorectal cancer KRAS_G12C ARID2 66 110 Tumor Type:overall -1.70 -4.77 0.55 1299.57 1.00 2058 65 109 1 FALSE 0.69
non-small cell lung cancer KRAS_G12C ARID2 456 182 Tumor Type:overall 0.22 -0.44 0.84 1324.44 1.00 3084 429 155 27 FALSE 0.29
colorectal cancer KRAS_G12C SOX17 37 30 Metastasis 0.03 -1.54 1.32 1520.72 1.00 816 35 28 2 FALSE 0.02
colorectal cancer KRAS_G12C SOX17 29 68 Primary -0.31 -2.16 1.04 1106.70 1.00 1249 28 67 1 FALSE 0.15
non-small cell lung cancer KRAS_G12C SOX17 166 26 Metastasis 0.66 -0.20 1.34 476.10 1.01 1194 162 22 4 FALSE 1.06
non-small cell lung cancer KRAS_G12C SOX17 289 35 Primary 0.82 0.10 1.47 1007.63 1.00 1986 279 25 10 FALSE 1.79
colorectal cancer KRAS_G12C SOX17 66 98 Tumor Type:overall -0.13 -1.96 1.51 1388.34 1.00 2065 63 95 3 FALSE 0.05
non-small cell lung cancer KRAS_G12C SOX17 455 61 Tumor Type:overall 0.74 -0.12 1.51 988.99 1.00 3180 441 47 14 FALSE 1.16
colorectal cancer KRAS_G12C MTOR 37 41 Metastasis -0.14 -1.85 0.81 9.39 1.11 805 36 40 1 TRUE 0.07
colorectal cancer KRAS_G12C MTOR 29 99 Primary 0.06 -1.13 1.02 NA 1.01 1233 26 96 3 TRUE 0.05
non-small cell lung cancer KRAS_G12C MTOR 167 39 Metastasis 0.53 -0.13 1.10 884.42 1.00 1184 160 32 7 TRUE 1.11
non-small cell lung cancer KRAS_G12C MTOR 290 76 Primary 0.58 0.06 1.10 983.84 1.00 1950 274 60 16 TRUE 1.54
colorectal cancer KRAS_G12C MTOR 66 140 Tumor Type:overall -0.01 -1.68 1.08 37.02 1.05 2038 62 136 4 TRUE 0.00
non-small cell lung cancer KRAS_G12C MTOR 457 115 Tumor Type:overall 0.56 -0.08 1.14 1020.57 1.00 3134 434 92 23 TRUE 1.08
non-small cell lung cancer KRAS_G12C RFWD2 166 22 Metastasis 0.64 -0.09 1.28 489.77 1.00 1199 161 17 5 FALSE 1.22
non-small cell lung cancer KRAS_G12C RFWD2 289 35 Primary 0.61 -0.10 1.25 426.82 1.00 1981 282 28 7 FALSE 1.19
non-small cell lung cancer KRAS_G12C RFWD2 455 57 Tumor Type:overall 0.63 -0.11 1.32 505.07 1.00 3180 443 45 12 FALSE 1.09
colorectal cancer KRAS_G12C IRS1 37 19 Metastasis -2.06 -6.58 0.52 1378.54 1.00 823 37 19 0 FALSE 0.59
colorectal cancer KRAS_G12C IRS1 29 78 Primary -1.38 -4.15 0.46 1447.84 1.00 1245 28 77 1 FALSE 0.63
non-small cell lung cancer KRAS_G12C IRS1 166 30 Metastasis -0.14 -1.01 0.66 1011.81 1.00 1190 162 26 4 FALSE 0.13
non-small cell lung cancer KRAS_G12C IRS1 289 43 Primary -0.23 -1.09 0.49 1152.81 1.00 1973 285 39 4 FALSE 0.23
colorectal cancer KRAS_G12C IRS1 66 97 Tumor Type:overall -1.63 -4.97 1.01 1430.16 1.00 2068 65 96 1 FALSE 0.56
non-small cell lung cancer KRAS_G12C IRS1 455 73 Tumor Type:overall -0.19 -1.17 0.67 1267.92 1.00 3163 447 65 8 FALSE 0.14
colorectal cancer KRAS_G12C NOTCH1 45 39 Metastasis -5.52 -12.74 -0.93 1222.65 1.00 875 45 39 0 TRUE 1.11
colorectal cancer KRAS_G12C NOTCH1 32 133 Primary -5.62 -12.74 -1.19 1241.72 1.00 1368 32 133 0 TRUE 1.17
non-small cell lung cancer KRAS_G12C NOTCH1 171 52 Metastasis -0.40 -1.26 0.26 714.92 1.00 1215 168 49 3 TRUE 0.52
non-small cell lung cancer KRAS_G12C NOTCH1 301 78 Primary -0.26 -0.96 0.37 371.79 1.01 2009 291 68 10 TRUE 0.36
colorectal cancer KRAS_G12C NOTCH1 77 172 Tumor Type:overall -5.40 -12.34 -0.98 1205.68 1.00 2243 77 172 0 TRUE 1.13
non-small cell lung cancer KRAS_G12C NOTCH1 472 130 Tumor Type:overall -0.33 -1.05 0.39 616.12 1.01 3224 459 117 13 TRUE 0.39
colorectal cancer KRAS_G12C NTRK1 37 16 Metastasis -4.90 -12.37 -0.21 1096.65 1.00 825 37 16 0 TRUE 0.91
colorectal cancer KRAS_G12C NTRK1 29 48 Primary -4.91 -12.20 -0.34 1058.93 1.00 1267 29 48 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C NTRK1 166 44 Metastasis 0.45 -0.30 1.06 1507.70 1.00 1180 159 37 7 TRUE 0.72
non-small cell lung cancer KRAS_G12C NTRK1 289 44 Primary 0.58 -0.05 1.21 1172.99 1.00 1976 279 34 10 TRUE 1.19
colorectal cancer KRAS_G12C NTRK1 66 64 Tumor Type:overall -4.75 -11.87 -0.20 1092.92 1.00 2092 66 64 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C NTRK1 455 88 Tumor Type:overall 0.51 -0.41 1.38 1355.16 1.00 3156 438 71 17 TRUE 0.51
non-small cell lung cancer KRAS_G12C INPP4A 166 21 Metastasis 0.43 -0.45 1.27 339.30 1.00 1201 161 16 5 FALSE 0.48
non-small cell lung cancer KRAS_G12C INPP4A 289 32 Primary 0.28 -0.69 1.07 281.98 1.00 1981 285 28 4 FALSE 0.27
non-small cell lung cancer KRAS_G12C INPP4A 455 53 Tumor Type:overall 0.36 -0.62 1.21 507.01 1.00 3182 446 44 9 FALSE 0.32
colorectal cancer KRAS_G12C CASP8 37 17 Metastasis -5.15 -11.69 -0.40 1204.75 1.00 826 37 17 0 FALSE 1.07
colorectal cancer KRAS_G12C CASP8 29 79 Primary -5.29 -12.26 -0.64 1214.12 1.00 1245 29 79 0 FALSE 1.08
colorectal cancer KRAS_G12C CASP8 66 96 Tumor Type:overall -5.06 -11.52 -0.21 1153.40 1.00 2071 66 96 0 FALSE 1.07
colorectal cancer KRAS_G12C SETD2 37 29 Metastasis -5.12 -12.58 -0.75 1346.25 1.00 817 37 29 0 FALSE 1.02
colorectal cancer KRAS_G12C SETD2 29 84 Primary -5.10 -12.00 -0.65 1160.81 1.00 1244 29 84 0 FALSE 1.04
non-small cell lung cancer KRAS_G12C SETD2 168 93 Metastasis 0.22 -0.26 0.68 1277.02 1.00 1152 154 79 14 FALSE 0.47
non-small cell lung cancer KRAS_G12C SETD2 292 132 Primary 0.19 -0.26 0.61 1308.68 1.00 1910 273 113 19 FALSE 0.43
colorectal cancer KRAS_G12C SETD2 66 113 Tumor Type:overall -5.01 -12.01 -0.61 1275.01 1.00 2061 66 113 0 FALSE 1.06
non-small cell lung cancer KRAS_G12C SETD2 460 225 Tumor Type:overall 0.21 -0.34 0.71 1302.75 1.00 3062 427 192 33 FALSE 0.37
colorectal cancer KRAS_G12C PBRM1 37 15 Metastasis -5.13 -12.62 -0.36 1555.29 1.00 828 37 15 0 TRUE 0.92
colorectal cancer KRAS_G12C PBRM1 29 79 Primary -5.13 -12.83 -0.58 1446.23 1.00 1244 29 79 0 TRUE 0.97
non-small cell lung cancer KRAS_G12C PBRM1 166 54 Metastasis -0.05 -0.75 0.63 1471.04 1.00 1176 160 48 6 TRUE 0.06
non-small cell lung cancer KRAS_G12C PBRM1 289 60 Primary -0.03 -0.71 0.60 1135.86 1.00 1964 281 52 8 TRUE 0.03
colorectal cancer KRAS_G12C PBRM1 66 94 Tumor Type:overall -4.92 -12.11 -0.25 1500.34 1.00 2072 66 94 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C PBRM1 455 114 Tumor Type:overall -0.04 -0.86 0.74 1404.22 1.00 3140 441 100 14 TRUE 0.04
colorectal cancer KRAS_G12C EPHA3 37 34 Metastasis -0.45 -2.36 1.10 1322.54 1.00 810 35 32 2 FALSE 0.22
colorectal cancer KRAS_G12C EPHA3 29 79 Primary -1.49 -5.21 0.40 1430.97 1.00 1243 29 79 0 FALSE 0.48
non-small cell lung cancer KRAS_G12C EPHA3 168 83 Metastasis 0.41 -0.03 0.81 1367.97 1.00 1149 155 70 13 FALSE 1.20
non-small cell lung cancer KRAS_G12C EPHA3 293 159 Primary 0.46 0.10 0.81 1516.69 1.00 1892 263 129 30 FALSE 1.97
colorectal cancer KRAS_G12C EPHA3 66 113 Tumor Type:overall -0.93 -3.65 1.10 1380.43 1.00 2053 64 111 2 FALSE 0.36
non-small cell lung cancer KRAS_G12C EPHA3 461 242 Tumor Type:overall 0.44 -0.06 0.88 1267.41 1.00 3041 418 199 43 FALSE 1.03
colorectal cancer KRAS_G12C KIT 45 17 Metastasis 0.60 -1.05 1.97 1620.33 1.00 894 43 15 2 TRUE 0.38
colorectal cancer KRAS_G12C KIT 32 37 Primary 0.27 -1.54 1.67 1475.04 1.00 1433 31 36 1 TRUE 0.12
non-small cell lung cancer KRAS_G12C KIT 171 30 Metastasis 0.69 0.06 1.24 546.32 1.01 1236 165 24 6 TRUE 1.69
non-small cell lung cancer KRAS_G12C KIT 300 51 Primary 0.71 0.12 1.24 729.69 1.00 2037 288 39 12 TRUE 1.97
colorectal cancer KRAS_G12C KIT 77 54 Tumor Type:overall 0.41 -1.53 1.92 1232.20 1.00 2327 74 51 3 TRUE 0.18
non-small cell lung cancer KRAS_G12C KIT 471 81 Tumor Type:overall 0.69 -0.02 1.30 839.64 1.00 3273 453 63 18 TRUE 1.27
colorectal cancer KRAS_G12C KDR 45 15 Metastasis -1.19 -5.29 1.06 1445.31 1.00 894 45 15 0 TRUE 0.31
colorectal cancer KRAS_G12C KDR 32 60 Primary -0.07 -1.90 1.34 1485.30 1.00 1418 30 58 2 TRUE 0.03
non-small cell lung cancer KRAS_G12C KDR 172 51 Metastasis 0.37 -0.18 1.01 1002.06 1.00 1221 161 40 11 TRUE 0.63
non-small cell lung cancer KRAS_G12C KDR 301 103 Primary 0.11 -0.50 0.61 532.88 1.01 1987 289 91 12 TRUE 0.16
colorectal cancer KRAS_G12C KDR 77 75 Tumor Type:overall -0.58 -3.53 1.90 1428.38 1.00 2312 75 73 2 TRUE 0.17
non-small cell lung cancer KRAS_G12C KDR 473 154 Tumor Type:overall 0.23 -0.47 0.94 1096.14 1.00 3208 450 131 23 TRUE 0.25
colorectal cancer KRAS_G12C RICTOR 37 11 Metastasis 0.86 -1.20 2.58 1572.10 1.00 834 35 9 2 FALSE 0.41
colorectal cancer KRAS_G12C RICTOR 29 59 Primary -1.77 -7.31 0.80 1304.97 1.00 1262 29 59 0 FALSE 0.38
non-small cell lung cancer KRAS_G12C RICTOR 166 24 Metastasis -0.34 -1.32 0.58 1383.52 1.00 1196 163 21 3 FALSE 0.31
non-small cell lung cancer KRAS_G12C RICTOR 289 40 Primary -0.42 -1.38 0.44 1271.87 1.00 1974 286 37 3 FALSE 0.44
colorectal cancer KRAS_G12C RICTOR 66 70 Tumor Type:overall -0.44 -4.34 2.58 1454.19 1.00 2096 64 68 2 FALSE 0.10
non-small cell lung cancer KRAS_G12C RICTOR 455 64 Tumor Type:overall -0.39 -1.45 0.55 1425.76 1.00 3170 449 58 6 FALSE 0.34
colorectal cancer KRAS_G12C RAD50 37 18 Metastasis -1.42 -5.09 0.78 1120.23 1.00 826 37 18 0 FALSE 0.45
colorectal cancer KRAS_G12C RAD50 29 42 Primary -0.89 -3.80 1.00 1317.66 1.00 1275 28 41 1 FALSE 0.33
colorectal cancer KRAS_G12C RAD50 66 60 Tumor Type:overall -1.13 -4.25 0.96 1256.28 1.00 2101 65 59 1 FALSE 0.39
colorectal cancer KRAS_G12C CSF1R 45 18 Metastasis -4.74 -11.83 -0.28 1221.09 1.00 895 45 18 0 TRUE 0.93
colorectal cancer KRAS_G12C CSF1R 32 38 Primary -4.71 -11.80 -0.11 1151.40 1.00 1430 32 38 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C CSF1R 171 31 Metastasis 0.35 -0.41 1.05 1021.08 1.01 1236 166 26 5 TRUE 0.45
non-small cell lung cancer KRAS_G12C CSF1R 300 38 Primary 0.35 -0.37 1.01 1112.22 1.00 2043 293 31 7 TRUE 0.50
colorectal cancer KRAS_G12C CSF1R 77 56 Tumor Type:overall -4.61 -11.55 -0.15 1181.87 1.00 2325 77 56 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C CSF1R 471 69 Tumor Type:overall 0.34 -0.52 1.12 1039.94 1.00 3279 459 57 12 TRUE 0.34
non-small cell lung cancer KRAS_G12C PARK2 166 31 Metastasis 0.16 -0.73 0.97 1300.11 1.00 1189 162 27 4 FALSE 0.16
non-small cell lung cancer KRAS_G12C PARK2 289 34 Primary 0.22 -0.54 0.98 1277.08 1.00 1981 283 28 6 FALSE 0.25
non-small cell lung cancer KRAS_G12C PARK2 455 65 Tumor Type:overall 0.19 -0.76 1.04 1344.85 1.00 3170 445 55 10 FALSE 0.16
non-small cell lung cancer KRAS_G12C NTRK2 166 22 Metastasis 0.41 -0.36 1.12 1299.08 1.00 1200 162 18 4 FALSE 0.57
non-small cell lung cancer KRAS_G12C NTRK2 290 45 Primary 0.42 -0.31 1.06 1187.00 1.00 1974 282 37 8 FALSE 0.64
non-small cell lung cancer KRAS_G12C NTRK2 456 67 Tumor Type:overall 0.42 -0.36 1.16 1269.60 1.00 3174 444 55 12 FALSE 0.53
colorectal cancer KRAS_G12C PTCH1 37 38 Metastasis -1.62 -4.37 0.37 1253.95 1.00 813 36 37 1 TRUE 0.72
colorectal cancer KRAS_G12C PTCH1 29 107 Primary -2.35 -5.77 -0.20 1481.25 1.00 1229 29 107 0 TRUE 0.95
non-small cell lung cancer KRAS_G12C PTCH1 166 27 Metastasis 0.40 -0.40 1.10 1067.33 1.00 1195 161 22 5 TRUE 0.52
non-small cell lung cancer KRAS_G12C PTCH1 289 35 Primary 0.37 -0.37 1.05 1068.15 1.00 1980 283 29 6 TRUE 0.49
colorectal cancer KRAS_G12C PTCH1 66 145 Tumor Type:overall -1.96 -5.03 0.33 1326.30 1.00 2042 65 144 1 TRUE 0.80
non-small cell lung cancer KRAS_G12C PTCH1 455 62 Tumor Type:overall 0.38 -0.43 1.16 1140.64 1.00 3175 444 51 11 TRUE 0.42
colorectal cancer KRAS_G12C TET1 37 35 Metastasis -1.48 -4.06 0.44 759.82 1.01 816 36 34 1 FALSE 0.66
colorectal cancer KRAS_G12C TET1 29 68 Primary -1.94 -5.30 0.12 960.77 1.01 1260 29 68 0 FALSE 0.74
non-small cell lung cancer KRAS_G12C TET1 166 58 Metastasis -0.27 -1.18 0.44 892.64 1.00 1169 162 54 4 FALSE 0.28
non-small cell lung cancer KRAS_G12C TET1 290 68 Primary 0.06 -0.57 0.69 1198.20 1.01 1956 279 57 11 FALSE 0.07
colorectal cancer KRAS_G12C TET1 66 103 Tumor Type:overall -1.68 -4.51 0.59 929.74 1.01 2076 65 102 1 FALSE 0.67
non-small cell lung cancer KRAS_G12C TET1 456 126 Tumor Type:overall -0.11 -1.14 0.80 1416.10 1.00 3125 441 111 15 FALSE 0.08
colorectal cancer KRAS_G12C FGFR2 45 19 Metastasis -4.71 -12.08 -0.27 1121.39 1.00 890 45 19 0 TRUE 0.92
colorectal cancer KRAS_G12C FGFR2 32 34 Primary -4.72 -11.98 -0.22 1126.69 1.00 1435 32 34 0 TRUE 0.87
colorectal cancer KRAS_G12C FGFR2 77 53 Tumor Type:overall -4.57 -11.70 -0.09 1128.92 1.00 2325 77 53 0 TRUE 0.89
colorectal cancer KRAS_G12C TBX3 37 18 Metastasis -5.01 -12.70 -0.46 1346.47 1.00 824 37 18 0 FALSE 0.95
colorectal cancer KRAS_G12C TBX3 29 62 Primary -5.01 -12.82 -0.38 1284.94 1.00 1262 29 62 0 FALSE 0.92
non-small cell lung cancer KRAS_G12C TBX3 166 60 Metastasis 0.38 -0.26 0.90 939.71 1.00 1171 157 51 9 FALSE 0.74
non-small cell lung cancer KRAS_G12C TBX3 289 77 Primary 0.44 -0.06 0.93 1087.93 1.00 1950 274 62 15 FALSE 1.08
colorectal cancer KRAS_G12C TBX3 66 80 Tumor Type:overall -4.82 -12.11 -0.23 1262.04 1.00 2086 66 80 0 FALSE 0.93
non-small cell lung cancer KRAS_G12C TBX3 455 137 Tumor Type:overall 0.40 -0.31 1.02 1048.01 1.00 3121 431 113 24 FALSE 0.62
colorectal cancer KRAS_G12C HNF1A 32 43 Primary -4.92 -14.42 0.13 1277.82 1.00 1423 32 43 0 TRUE 0.68
colorectal cancer KRAS_G12C HNF1A 32 43 Tumor Type:overall -3.65 -11.00 2.91 1329.83 1.00 1423 32 43 0 TRUE 0.50
colorectal cancer KRAS_G12C DICER1 37 27 Metastasis -5.03 -11.53 -0.55 498.85 1.01 819 37 27 0 TRUE 1.10
colorectal cancer KRAS_G12C DICER1 29 49 Primary -5.08 -11.77 -0.60 758.41 1.01 1272 29 49 0 TRUE 1.10
non-small cell lung cancer KRAS_G12C DICER1 166 33 Metastasis 0.11 -0.61 0.71 1052.41 1.00 1190 162 29 4 TRUE 0.13
non-small cell lung cancer KRAS_G12C DICER1 289 57 Primary 0.15 -0.48 0.74 894.45 1.00 1964 280 48 9 TRUE 0.20
colorectal cancer KRAS_G12C DICER1 66 76 Tumor Type:overall -4.97 -11.14 -0.54 635.87 1.01 2091 66 76 0 TRUE 1.12
non-small cell lung cancer KRAS_G12C DICER1 455 90 Tumor Type:overall 0.15 -0.56 0.81 1169.57 1.00 3154 442 77 13 TRUE 0.16
colorectal cancer KRAS_G12C SMAD3 37 38 Metastasis -1.52 -4.56 0.42 1381.34 1.00 807 36 37 1 TRUE 0.65
colorectal cancer KRAS_G12C SMAD3 29 69 Primary -2.02 -5.54 0.14 1295.98 1.00 1254 29 69 0 TRUE 0.76
colorectal cancer KRAS_G12C SMAD3 66 107 Tumor Type:overall -1.73 -5.00 0.51 1371.16 1.00 2061 65 106 1 TRUE 0.68
colorectal cancer KRAS_G12C NTRK3 37 15 Metastasis -1.62 -5.67 0.87 1363.99 1.00 828 37 15 0 FALSE 0.48
colorectal cancer KRAS_G12C NTRK3 29 55 Primary -1.07 -4.18 0.81 1346.49 1.00 1264 28 54 1 FALSE 0.40
non-small cell lung cancer KRAS_G12C NTRK3 166 81 Metastasis 0.82 0.38 1.22 1076.97 1.00 1157 150 65 16 FALSE 3.97
non-small cell lung cancer KRAS_G12C NTRK3 293 126 Primary 0.92 0.58 1.29 572.83 1.00 1934 258 91 35 FALSE 6.37
colorectal cancer KRAS_G12C NTRK3 66 70 Tumor Type:overall -1.30 -4.71 1.14 1477.91 1.00 2092 65 69 1 FALSE 0.42
non-small cell lung cancer KRAS_G12C NTRK3 459 207 Tumor Type:overall 0.87 0.44 1.32 1110.10 1.00 3091 408 156 51 FALSE 3.17
colorectal cancer KRAS_G12C AXIN1 37 17 Metastasis -4.80 -12.37 -0.24 1278.96 1.00 827 37 17 0 FALSE 0.92
colorectal cancer KRAS_G12C AXIN1 29 54 Primary -4.83 -12.65 -0.37 1208.78 1.00 1264 29 54 0 FALSE 0.92
colorectal cancer KRAS_G12C AXIN1 66 71 Tumor Type:overall -4.66 -12.12 -0.23 1232.86 1.00 2091 66 71 0 FALSE 0.92
colorectal cancer KRAS_G12C GRIN2A 37 41 Metastasis 0.51 -0.82 1.73 1365.49 1.00 805 33 37 4 FALSE 0.36
colorectal cancer KRAS_G12C GRIN2A 29 95 Primary -1.62 -7.10 0.52 1305.38 1.00 1230 29 95 0 FALSE 0.39
non-small cell lung cancer KRAS_G12C GRIN2A 166 80 Metastasis 0.20 -0.26 0.65 1076.97 1.00 1152 154 68 12 FALSE 0.39
non-small cell lung cancer KRAS_G12C GRIN2A 292 113 Primary 0.16 -0.29 0.56 1090.07 1.00 1917 276 97 16 FALSE 0.32
colorectal cancer KRAS_G12C GRIN2A 66 136 Tumor Type:overall -0.42 -3.63 1.97 1393.42 1.00 2035 62 132 4 FALSE 0.12
non-small cell lung cancer KRAS_G12C GRIN2A 458 193 Tumor Type:overall 0.18 -0.34 0.69 1190.26 1.00 3069 430 165 28 FALSE 0.31
colorectal cancer KRAS_G12C PALB2 29 47 Primary -5.18 -14.80 0.13 1184.05 1.00 1269 29 47 0 TRUE 0.66
non-small cell lung cancer KRAS_G12C PALB2 166 28 Metastasis 0.50 -0.28 1.25 1477.18 1.00 1197 160 22 6 TRUE 0.69
non-small cell lung cancer KRAS_G12C PALB2 289 32 Primary 0.36 -0.53 1.03 1090.97 1.00 1982 284 27 5 TRUE 0.45
colorectal cancer KRAS_G12C PALB2 29 47 Tumor Type:overall -3.83 -11.11 3.37 829.23 1.00 1269 29 47 0 TRUE 0.52
non-small cell lung cancer KRAS_G12C PALB2 455 60 Tumor Type:overall 0.42 -0.54 1.35 1413.09 1.00 3179 444 49 11 TRUE 0.41
colorectal cancer KRAS_G12C CTCF 37 24 Metastasis -0.51 -2.54 1.03 1555.59 1.00 822 36 23 1 FALSE 0.23
colorectal cancer KRAS_G12C CTCF 29 66 Primary -0.61 -2.61 0.84 1617.19 1.00 1256 28 65 1 FALSE 0.29
colorectal cancer KRAS_G12C CTCF 66 90 Tumor Type:overall -0.55 -2.80 1.21 1438.35 1.00 2078 64 88 2 FALSE 0.22
colorectal cancer KRAS_G12C CDH1 45 13 Metastasis -4.77 -12.17 -0.02 563.17 1.00 898 45 13 0 TRUE 0.82
colorectal cancer KRAS_G12C CDH1 32 41 Primary -4.80 -12.24 -0.26 585.95 1.00 1430 32 41 0 TRUE 0.83
colorectal cancer KRAS_G12C CDH1 77 54 Tumor Type:overall -4.62 -11.45 0.06 528.52 1.00 2328 77 54 0 TRUE 0.82
colorectal cancer KRAS_G12C CDK12 37 21 Metastasis -1.30 -4.92 0.79 1394.79 1.00 825 37 21 0 FALSE 0.38
colorectal cancer KRAS_G12C CDK12 30 69 Primary -0.32 -2.26 1.20 1591.69 1.00 1253 28 67 2 FALSE 0.14
non-small cell lung cancer KRAS_G12C CDK12 166 24 Metastasis -0.49 -1.60 0.43 852.43 1.00 1194 164 22 2 FALSE 0.47
non-small cell lung cancer KRAS_G12C CDK12 289 35 Primary -0.50 -1.53 0.37 1129.71 1.00 1979 286 32 3 FALSE 0.52
colorectal cancer KRAS_G12C CDK12 67 90 Tumor Type:overall -0.76 -3.49 1.33 1757.12 1.00 2078 65 88 2 FALSE 0.27
non-small cell lung cancer KRAS_G12C CDK12 455 59 Tumor Type:overall -0.49 -1.64 0.42 1084.20 1.00 3173 450 54 5 FALSE 0.47
non-small cell lung cancer KRAS_G12C STK11 172 205 Metastasis 0.94 0.60 1.19 192.95 1.02 1100 129 162 43 TRUE 9.54
non-small cell lung cancer KRAS_G12C STK11 304 338 Primary 1.01 0.77 1.26 890.08 1.00 1834 217 251 87 TRUE 15.65
non-small cell lung cancer KRAS_G12C STK11 476 543 Tumor Type:overall 0.98 0.60 1.30 1062.56 1.01 2934 346 413 130 TRUE 6.46
colorectal cancer KRAS_G12C DNMT1 37 27 Metastasis -5.00 -11.95 -0.65 869.81 1.00 818 37 27 0 FALSE 0.97
colorectal cancer KRAS_G12C DNMT1 29 63 Primary -5.01 -12.17 -0.56 859.52 1.00 1255 29 63 0 FALSE 0.97
colorectal cancer KRAS_G12C DNMT1 66 90 Tumor Type:overall -4.88 -11.68 -0.45 935.47 1.00 2073 66 90 0 FALSE 0.95
colorectal cancer KRAS_G12C BRD4 37 22 Metastasis -1.26 -5.32 0.79 1205.03 1.00 822 37 22 0 FALSE 0.34
colorectal cancer KRAS_G12C BRD4 30 66 Primary -0.31 -2.38 1.17 1125.30 1.00 1251 28 64 2 FALSE 0.14
non-small cell lung cancer KRAS_G12C BRD4 167 27 Metastasis 0.14 -0.78 1.04 830.98 1.01 1195 162 22 5 FALSE 0.12
non-small cell lung cancer KRAS_G12C BRD4 289 26 Primary -0.21 -1.47 0.70 1327.62 1.00 1985 287 24 2 FALSE 0.15
colorectal cancer KRAS_G12C BRD4 67 88 Tumor Type:overall -0.76 -3.87 1.32 1371.19 1.00 2073 65 86 2 FALSE 0.26
non-small cell lung cancer KRAS_G12C BRD4 456 53 Tumor Type:overall -0.02 -1.25 1.00 1461.92 1.00 3180 449 46 7 FALSE 0.01
colorectal cancer KRAS_G12C ASXL1 37 34 Metastasis -0.42 -2.27 1.12 1377.24 1.00 810 35 32 2 TRUE 0.21
colorectal cancer KRAS_G12C ASXL1 29 75 Primary -1.46 -5.45 0.32 1253.46 1.00 1246 29 75 0 TRUE 0.47
non-small cell lung cancer KRAS_G12C ASXL1 166 44 Metastasis -0.22 -1.11 0.60 1278.39 1.00 1189 162 40 4 TRUE 0.22
non-small cell lung cancer KRAS_G12C ASXL1 289 42 Primary -0.06 -0.84 0.71 1383.09 1.00 1974 283 36 6 TRUE 0.06
colorectal cancer KRAS_G12C ASXL1 66 109 Tumor Type:overall -0.87 -3.66 1.03 1445.87 1.00 2056 64 107 2 TRUE 0.34
non-small cell lung cancer KRAS_G12C ASXL1 455 86 Tumor Type:overall -0.13 -1.12 0.89 1425.69 1.00 3163 445 76 10 TRUE 0.09
colorectal cancer KRAS_G12C EP300 37 38 Metastasis -1.62 -4.42 0.38 1425.83 1.00 810 36 37 1 TRUE 0.71
colorectal cancer KRAS_G12C EP300 29 87 Primary -2.19 -5.85 -0.04 1443.88 1.00 1243 29 87 0 TRUE 0.80
non-small cell lung cancer KRAS_G12C EP300 166 57 Metastasis 0.14 -0.60 0.86 1512.40 1.00 1174 157 48 9 TRUE 0.16
non-small cell lung cancer KRAS_G12C EP300 289 51 Primary -0.33 -1.27 0.43 1434.05 1.00 1967 285 47 4 TRUE 0.36
colorectal cancer KRAS_G12C EP300 66 125 Tumor Type:overall -1.85 -4.88 0.43 1445.11 1.00 2053 65 124 1 TRUE 0.73
non-small cell lung cancer KRAS_G12C EP300 455 108 Tumor Type:overall -0.10 -1.30 1.02 1329.67 1.00 3141 442 95 13 TRUE 0.06
colorectal cancer KRAS_G12C ERBB4 45 50 Metastasis -1.08 -3.12 0.29 1535.21 1.00 862 44 49 1 TRUE 0.68
colorectal cancer KRAS_G12C ERBB4 32 88 Primary -1.09 -3.15 0.36 1381.86 1.00 1395 31 87 1 TRUE 0.66
non-small cell lung cancer KRAS_G12C ERBB4 172 88 Metastasis -0.48 -1.15 0.11 1082.78 1.00 1193 164 80 8 TRUE 0.87
non-small cell lung cancer KRAS_G12C ERBB4 300 105 Primary -0.63 -1.29 -0.05 1087.47 1.00 1990 293 98 7 TRUE 1.35
colorectal cancer KRAS_G12C ERBB4 77 138 Tumor Type:overall -1.09 -3.19 0.69 971.10 1.00 2257 75 136 2 TRUE 0.57
non-small cell lung cancer KRAS_G12C ERBB4 472 193 Tumor Type:overall -0.56 -1.30 0.13 1034.77 1.00 3183 457 178 15 TRUE 0.77
colorectal cancer KRAS_G12C MDC1 37 13 Metastasis -4.74 -12.67 0.08 1500.64 1.00 828 37 13 0 FALSE 0.88
colorectal cancer KRAS_G12C MDC1 29 52 Primary -4.82 -12.00 -0.26 1546.76 1.00 1268 29 52 0 FALSE 0.93
non-small cell lung cancer KRAS_G12C MDC1 169 60 Metastasis 0.05 -0.72 0.73 1504.33 1.00 1172 161 52 8 FALSE 0.05
non-small cell lung cancer KRAS_G12C MDC1 289 35 Primary -0.15 -1.08 0.65 1471.12 1.00 1978 285 31 4 FALSE 0.13
colorectal cancer KRAS_G12C MDC1 66 65 Tumor Type:overall -4.58 -11.47 0.21 1493.91 1.00 2096 66 65 0 FALSE 0.89
non-small cell lung cancer KRAS_G12C MDC1 458 95 Tumor Type:overall -0.06 -1.64 1.37 1328.88 1.00 3150 446 83 12 FALSE 0.03
colorectal cancer KRAS_G12C RECQL4 37 20 Metastasis -5.02 -12.41 -0.31 1102.91 1.00 824 37 20 0 TRUE 0.87
colorectal cancer KRAS_G12C RECQL4 29 61 Primary -5.05 -12.64 -0.49 957.52 1.00 1258 29 61 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C RECQL4 166 23 Metastasis -0.90 -2.22 0.24 646.23 1.00 1194 165 22 1 TRUE 0.77
non-small cell lung cancer KRAS_G12C RECQL4 289 41 Primary -0.84 -2.01 0.26 508.10 1.00 1974 286 38 3 TRUE 0.84
colorectal cancer KRAS_G12C RECQL4 66 81 Tumor Type:overall -4.82 -11.97 -0.36 1139.61 1.00 2082 66 81 0 TRUE 0.93
non-small cell lung cancer KRAS_G12C RECQL4 455 64 Tumor Type:overall -0.87 -2.25 0.31 740.90 1.00 3168 451 60 4 TRUE 0.68
colorectal cancer KRAS_G12C MED12 38 28 Metastasis 0.81 -0.45 1.89 1410.93 1.00 821 35 25 3 TRUE 0.78
colorectal cancer KRAS_G12C MED12 29 80 Primary 0.57 -0.67 1.60 1586.48 1.00 1244 26 77 3 TRUE 0.49
non-small cell lung cancer KRAS_G12C MED12 167 57 Metastasis -0.04 -0.65 0.58 1353.50 1.00 1170 159 49 8 TRUE 0.04
non-small cell lung cancer KRAS_G12C MED12 291 119 Primary -0.10 -0.62 0.36 1207.74 1.00 1911 278 106 13 TRUE 0.15
colorectal cancer KRAS_G12C MED12 67 108 Tumor Type:overall 0.71 -0.79 2.21 1359.45 1.00 2065 61 102 6 TRUE 0.44
non-small cell lung cancer KRAS_G12C MED12 458 176 Tumor Type:overall -0.05 -0.69 0.59 1502.63 1.00 3081 437 155 21 TRUE 0.06
colorectal cancer KRAS_G12C ERCC5 37 14 Metastasis -1.50 -5.88 0.94 1245.81 1.00 828 37 14 0 TRUE 0.42
colorectal cancer KRAS_G12C ERCC5 29 44 Primary -0.86 -3.77 1.12 1153.72 1.00 1272 28 43 1 TRUE 0.31
non-small cell lung cancer KRAS_G12C ERCC5 166 30 Metastasis 0.33 -0.45 1.00 912.53 1.00 1192 161 25 5 TRUE 0.45
non-small cell lung cancer KRAS_G12C ERCC5 289 43 Primary 0.31 -0.41 0.91 838.24 1.00 1978 282 36 7 TRUE 0.46
colorectal cancer KRAS_G12C ERCC5 66 58 Tumor Type:overall -1.15 -4.42 1.30 1167.76 1.00 2100 65 57 1 TRUE 0.38
non-small cell lung cancer KRAS_G12C ERCC5 455 73 Tumor Type:overall 0.33 -0.44 1.03 957.45 1.00 3170 443 61 12 TRUE 0.40
colorectal cancer KRAS_G12C PIK3CD 37 24 Metastasis -0.30 -1.92 1.43 16.85 1.13 822 35 22 2 FALSE 0.12
colorectal cancer KRAS_G12C PIK3CD 29 45 Primary -1.02 -4.09 0.80 407.62 1.01 1269 29 45 0 FALSE 0.35
colorectal cancer KRAS_G12C PIK3CD 66 69 Tumor Type:overall -0.62 -2.70 1.31 49.53 1.05 2091 64 67 2 FALSE 0.23
colorectal cancer KRAS_G12C BRCA1 37 17 Metastasis -4.89 -12.61 -0.28 1227.42 1.00 824 37 17 0 TRUE 0.91
colorectal cancer KRAS_G12C BRCA1 29 62 Primary -4.92 -12.70 -0.29 1230.08 1.00 1264 29 62 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C BRCA1 166 41 Metastasis 0.07 -0.69 0.67 1279.91 1.00 1180 162 37 4 TRUE 0.08
non-small cell lung cancer KRAS_G12C BRCA1 289 56 Primary 0.20 -0.40 0.84 799.84 1.01 1967 279 46 10 TRUE 0.28
colorectal cancer KRAS_G12C BRCA1 66 79 Tumor Type:overall -4.77 -12.04 -0.29 1200.65 1.00 2088 66 79 0 TRUE 0.92
non-small cell lung cancer KRAS_G12C BRCA1 455 97 Tumor Type:overall 0.13 -0.70 0.84 1497.82 1.00 3147 441 83 14 TRUE 0.12
colorectal cancer KRAS_G12C RBM10 37 22 Metastasis -4.75 -12.05 -0.42 493.23 1.00 819 37 22 0 FALSE 0.91
colorectal cancer KRAS_G12C RBM10 29 50 Primary -4.69 -11.96 -0.22 564.98 1.00 1268 29 50 0 FALSE 0.87
non-small cell lung cancer KRAS_G12C RBM10 169 122 Metastasis 0.69 0.29 1.15 1417.46 1.00 1125 141 94 28 FALSE 2.84
non-small cell lung cancer KRAS_G12C RBM10 290 261 Primary 0.48 0.15 0.78 1544.32 1.00 1805 246 217 44 FALSE 2.41
colorectal cancer KRAS_G12C RBM10 66 72 Tumor Type:overall -4.61 -11.77 -0.26 557.33 1.00 2087 66 72 0 FALSE 0.91
non-small cell lung cancer KRAS_G12C RBM10 459 383 Tumor Type:overall 0.58 0.02 1.21 1272.04 1.00 2930 387 311 72 FALSE 1.04
colorectal cancer KRAS_G12C TSC1 37 16 Metastasis -0.74 -3.56 1.31 1400.92 1.00 829 36 15 1 TRUE 0.26
colorectal cancer KRAS_G12C TSC1 29 51 Primary -1.58 -5.17 0.61 1354.78 1.00 1269 29 51 0 TRUE 0.49
non-small cell lung cancer KRAS_G12C TSC1 166 25 Metastasis 0.58 -0.29 1.47 1003.41 1.00 1198 159 18 7 TRUE 0.72
non-small cell lung cancer KRAS_G12C TSC1 289 32 Primary 0.16 -0.89 0.99 1410.78 1.00 1981 286 29 3 TRUE 0.13
colorectal cancer KRAS_G12C TSC1 66 67 Tumor Type:overall -1.11 -4.10 1.16 1397.69 1.00 2098 65 66 1 TRUE 0.37
non-small cell lung cancer KRAS_G12C TSC1 455 57 Tumor Type:overall 0.37 -0.69 1.38 1400.31 1.00 3179 445 47 10 TRUE 0.30
colorectal cancer KRAS_G12C FLCN 37 18 Metastasis -4.34 -11.57 0.10 902.44 1.00 826 37 18 0 TRUE 0.82
colorectal cancer KRAS_G12C FLCN 29 36 Primary -4.36 -11.75 0.04 955.46 1.00 1278 29 36 0 TRUE 0.83
colorectal cancer KRAS_G12C FLCN 66 54 Tumor Type:overall -4.27 -11.04 0.14 875.98 1.00 2104 66 54 0 TRUE 0.83
colorectal cancer KRAS_G12C NF1 37 37 Metastasis -1.61 -4.53 0.38 1508.02 1.00 811 36 36 1 TRUE 0.72
colorectal cancer KRAS_G12C NF1 29 105 Primary -2.33 -5.84 -0.08 1565.20 1.00 1236 29 105 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C NF1 166 125 Metastasis -0.41 -0.89 0.02 893.28 1.00 1118 157 116 9 TRUE 1.08
non-small cell lung cancer KRAS_G12C NF1 292 190 Primary -0.34 -0.74 0.04 730.52 1.00 1863 272 170 20 TRUE 1.01
colorectal cancer KRAS_G12C NF1 66 142 Tumor Type:overall -1.93 -5.13 0.45 1480.93 1.00 2047 65 141 1 TRUE 0.78
non-small cell lung cancer KRAS_G12C NF1 458 315 Tumor Type:overall -0.38 -0.88 0.06 1367.99 1.00 2981 429 286 29 TRUE 0.83
colorectal cancer KRAS_G12C FLT1 37 20 Metastasis -5.05 -12.23 -0.43 1140.69 1.00 824 37 20 0 FALSE 0.97
colorectal cancer KRAS_G12C FLT1 29 62 Primary -5.13 -12.52 -0.62 1216.40 1.00 1261 29 62 0 FALSE 1.00
non-small cell lung cancer KRAS_G12C FLT1 167 52 Metastasis 0.47 -0.04 0.94 860.45 1.00 1177 158 43 9 FALSE 1.23
non-small cell lung cancer KRAS_G12C FLT1 291 84 Primary 0.48 -0.01 0.89 857.92 1.00 1946 275 68 16 FALSE 1.43
colorectal cancer KRAS_G12C FLT1 66 82 Tumor Type:overall -4.95 -11.78 -0.47 1195.87 1.00 2085 66 82 0 FALSE 1.00
non-small cell lung cancer KRAS_G12C FLT1 458 136 Tumor Type:overall 0.47 -0.08 0.94 1127.06 1.00 3123 433 111 25 FALSE 0.96
colorectal cancer KRAS_G12C RPTOR 37 19 Metastasis -1.56 -5.32 0.77 1308.19 1.00 826 37 19 0 FALSE 0.50
colorectal cancer KRAS_G12C RPTOR 29 51 Primary -1.07 -3.98 0.92 1398.54 1.00 1264 28 50 1 FALSE 0.41
non-small cell lung cancer KRAS_G12C RPTOR 166 27 Metastasis 0.06 -0.81 0.88 521.65 1.01 1195 161 22 5 FALSE 0.05
non-small cell lung cancer KRAS_G12C RPTOR 289 38 Primary -0.13 -1.12 0.55 219.65 1.03 1975 286 35 3 FALSE 0.12
colorectal cancer KRAS_G12C RPTOR 66 70 Tumor Type:overall -1.29 -4.62 1.10 1364.64 1.00 2090 65 69 1 FALSE 0.44
non-small cell lung cancer KRAS_G12C RPTOR 455 65 Tumor Type:overall -0.04 -1.11 0.85 631.26 1.01 3170 447 57 8 FALSE 0.03
colorectal cancer KRAS_G12C RASA1 37 17 Metastasis -1.69 -5.59 0.85 1405.32 1.00 826 37 17 0 FALSE 0.49
colorectal cancer KRAS_G12C RASA1 29 56 Primary -1.14 -3.96 0.93 1409.78 1.00 1271 28 55 1 FALSE 0.42
non-small cell lung cancer KRAS_G12C RASA1 166 38 Metastasis -0.93 -1.84 0.01 102.37 1.03 1181 164 36 2 FALSE 1.47
non-small cell lung cancer KRAS_G12C RASA1 289 60 Primary -0.92 -1.74 -0.08 87.99 1.03 1954 285 56 4 FALSE 1.61
colorectal cancer KRAS_G12C RASA1 66 73 Tumor Type:overall -1.35 -4.58 1.23 1447.08 1.00 2097 65 72 1 FALSE 0.43
non-small cell lung cancer KRAS_G12C RASA1 455 98 Tumor Type:overall -0.92 -1.87 -0.02 528.62 1.02 3135 449 92 6 FALSE 1.27
colorectal cancer KRAS_G12C EPHA5 37 43 Metastasis -0.62 -2.49 0.83 1403.70 1.00 803 35 41 2 FALSE 0.33
colorectal cancer KRAS_G12C EPHA5 29 101 Primary -1.77 -5.44 0.20 1448.92 1.00 1233 29 101 0 FALSE 0.61
non-small cell lung cancer KRAS_G12C EPHA5 168 108 Metastasis 0.83 0.45 1.30 128.76 1.03 1143 140 80 28 FALSE 3.38
non-small cell lung cancer KRAS_G12C EPHA5 289 152 Primary 0.55 0.11 0.93 846.51 1.00 1898 263 126 26 FALSE 2.13
colorectal cancer KRAS_G12C EPHA5 66 144 Tumor Type:overall -1.16 -4.08 0.86 1474.95 1.00 2036 64 142 2 FALSE 0.45
non-small cell lung cancer KRAS_G12C EPHA5 457 260 Tumor Type:overall 0.68 0.06 1.29 800.39 1.01 3041 403 206 54 FALSE 1.47
colorectal cancer KRAS_G12C AR 37 21 Metastasis -5.40 -13.41 -0.74 164.60 1.02 820 37 21 0 TRUE 0.98
colorectal cancer KRAS_G12C AR 29 95 Primary -5.41 -13.29 -0.89 173.27 1.02 1229 29 95 0 TRUE 1.02
non-small cell lung cancer KRAS_G12C AR 168 39 Metastasis 0.34 -0.24 1.00 404.42 1.00 1186 160 31 8 TRUE 0.52
non-small cell lung cancer KRAS_G12C AR 290 71 Primary 0.25 -0.28 0.79 575.74 1.00 1953 280 61 10 TRUE 0.41
colorectal cancer KRAS_G12C AR 66 116 Tumor Type:overall -5.20 -12.98 -0.37 148.93 1.02 2049 66 116 0 TRUE 0.98
non-small cell lung cancer KRAS_G12C AR 458 110 Tumor Type:overall 0.29 -0.36 0.90 614.56 1.00 3139 440 92 18 TRUE 0.41
colorectal cancer KRAS_G12C GNAS 45 20 Metastasis -5.16 -12.62 -0.55 878.77 1.00 888 45 20 0 TRUE 0.94
colorectal cancer KRAS_G12C GNAS 32 55 Primary -5.15 -12.51 -0.60 885.77 1.00 1415 32 55 0 TRUE 0.96
colorectal cancer KRAS_G12C GNAS 77 75 Tumor Type:overall -4.97 -12.17 -0.45 831.51 1.00 2303 77 75 0 TRUE 0.93
colorectal cancer KRAS_G12C ASXL2 37 15 Metastasis -0.76 -3.75 1.37 1489.38 1.00 829 36 14 1 FALSE 0.25
colorectal cancer KRAS_G12C ASXL2 29 56 Primary -1.77 -5.87 0.54 1363.49 1.00 1274 29 56 0 FALSE 0.51
non-small cell lung cancer KRAS_G12C ASXL2 167 29 Metastasis 0.55 -0.11 1.27 40.21 1.07 1193 161 23 6 FALSE 0.85
non-small cell lung cancer KRAS_G12C ASXL2 289 34 Primary 0.53 -0.08 1.21 60.86 1.05 1984 282 27 7 FALSE 0.87
colorectal cancer KRAS_G12C ASXL2 66 71 Tumor Type:overall -1.25 -4.71 1.15 1407.84 1.00 2103 65 70 1 FALSE 0.39
non-small cell lung cancer KRAS_G12C ASXL2 456 63 Tumor Type:overall 0.53 -0.28 1.35 102.63 1.03 3177 443 50 13 FALSE 0.69
colorectal cancer KRAS_G12C SF3B1 37 21 Metastasis -4.87 -11.96 -0.38 660.60 1.00 829 37 21 0 TRUE 0.90
colorectal cancer KRAS_G12C SF3B1 29 49 Primary -4.88 -11.58 -0.32 537.30 1.00 1270 29 49 0 TRUE 0.94
non-small cell lung cancer KRAS_G12C SF3B1 166 33 Metastasis -0.72 -1.97 0.01 124.34 1.04 1184 165 32 1 TRUE 0.82
non-small cell lung cancer KRAS_G12C SF3B1 291 54 Primary -0.63 -1.59 0.07 152.24 1.02 1963 286 49 5 TRUE 0.85
colorectal cancer KRAS_G12C SF3B1 66 70 Tumor Type:overall -4.76 -11.57 -0.26 527.02 1.00 2099 66 70 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C SF3B1 457 87 Tumor Type:overall -0.67 -1.82 0.10 151.12 1.03 3147 451 81 6 TRUE 0.76
colorectal cancer KRAS_G12C MLH1 45 12 Metastasis -4.73 -11.89 -0.12 1530.04 1.00 896 45 12 0 TRUE 0.86
colorectal cancer KRAS_G12C MLH1 32 44 Primary -4.80 -12.09 -0.22 1438.49 1.00 1430 32 44 0 TRUE 0.88
colorectal cancer KRAS_G12C MLH1 77 56 Tumor Type:overall -4.58 -11.37 0.13 1477.45 1.00 2326 77 56 0 TRUE 0.86
colorectal cancer KRAS_G12C ROS1 37 33 Metastasis -1.91 -5.44 0.24 1085.94 1.00 814 37 33 0 TRUE 0.67
colorectal cancer KRAS_G12C ROS1 29 70 Primary -1.42 -4.04 0.46 1325.84 1.00 1259 28 69 1 TRUE 0.61
non-small cell lung cancer KRAS_G12C ROS1 166 35 Metastasis -0.46 -1.34 0.36 1381.25 1.00 1185 162 31 4 TRUE 0.55
non-small cell lung cancer KRAS_G12C ROS1 290 76 Primary -0.57 -1.36 0.12 1134.63 1.00 1942 285 71 5 TRUE 0.90
colorectal cancer KRAS_G12C ROS1 66 103 Tumor Type:overall -1.62 -4.81 0.50 1177.78 1.00 2073 65 102 1 TRUE 0.61
non-small cell lung cancer KRAS_G12C ROS1 456 111 Tumor Type:overall -0.51 -1.48 0.32 1548.61 1.00 3127 447 102 9 TRUE 0.58
colorectal cancer KRAS_G12C PIK3R2 29 42 Primary -5.33 -15.16 0.03 386.51 1.01 1273 29 42 0 FALSE 0.40
colorectal cancer KRAS_G12C PIK3R2 29 42 Tumor Type:overall -3.66 -11.06 2.79 1246.76 1.00 1273 29 42 0 FALSE 0.52
colorectal cancer KRAS_G12C FLT3 45 13 Metastasis -4.62 -11.48 -0.02 1532.44 1.00 898 45 13 0 TRUE 0.88
colorectal cancer KRAS_G12C FLT3 32 39 Primary -4.64 -11.58 -0.05 1364.32 1.00 1432 32 39 0 TRUE 0.85
non-small cell lung cancer KRAS_G12C FLT3 171 41 Metastasis 0.07 -0.94 0.85 1234.00 1.00 1227 167 37 4 TRUE 0.06
non-small cell lung cancer KRAS_G12C FLT3 301 40 Primary 0.59 -0.10 1.30 1292.54 1.00 2043 291 30 10 TRUE 1.00
colorectal cancer KRAS_G12C FLT3 77 52 Tumor Type:overall -4.53 -11.29 0.01 1388.22 1.00 2330 77 52 0 TRUE 0.87
non-small cell lung cancer KRAS_G12C FLT3 472 81 Tumor Type:overall 0.33 -0.94 1.40 1386.93 1.00 3270 458 67 14 TRUE 0.23
colorectal cancer KRAS_G12C MSH2 37 22 Metastasis -1.07 -3.89 0.99 1384.66 1.00 825 36 21 1 TRUE 0.40
colorectal cancer KRAS_G12C MSH2 29 61 Primary -1.85 -6.06 0.41 1450.07 1.00 1267 29 61 0 TRUE 0.59
non-small cell lung cancer KRAS_G12C MSH2 166 24 Metastasis -0.58 -1.88 0.41 1364.10 1.00 1196 165 23 1 TRUE 0.49
non-small cell lung cancer KRAS_G12C MSH2 289 32 Primary -0.43 -1.45 0.50 1300.89 1.00 1982 285 28 4 TRUE 0.41
colorectal cancer KRAS_G12C MSH2 66 83 Tumor Type:overall -1.40 -4.44 1.01 1418.61 1.00 2092 65 82 1 TRUE 0.49
non-small cell lung cancer KRAS_G12C MSH2 455 56 Tumor Type:overall -0.50 -1.71 0.56 1435.45 1.00 3178 450 51 5 TRUE 0.42
non-small cell lung cancer KRAS_G12C DIS3 166 27 Metastasis 0.47 -0.38 1.18 836.10 1.00 1193 162 23 4 FALSE 0.63
non-small cell lung cancer KRAS_G12C DIS3 289 38 Primary 0.56 -0.14 1.20 655.96 1.00 1982 280 29 9 FALSE 0.95
non-small cell lung cancer KRAS_G12C DIS3 455 65 Tumor Type:overall 0.51 -0.33 1.34 1236.23 1.00 3175 442 52 13 FALSE 0.62
colorectal cancer KRAS_G12C AXL 37 22 Metastasis -1.88 -5.49 0.39 1311.70 1.00 823 37 22 0 FALSE 0.61
colorectal cancer KRAS_G12C AXL 29 66 Primary -1.30 -4.10 0.68 1372.94 1.00 1257 28 65 1 FALSE 0.55
colorectal cancer KRAS_G12C AXL 66 88 Tumor Type:overall -1.53 -4.68 0.90 1487.80 1.00 2080 65 87 1 FALSE 0.55
colorectal cancer KRAS_G12C PIK3CG 37 34 Metastasis -5.27 -12.11 -0.67 536.45 1.00 810 37 34 0 FALSE 1.03
colorectal cancer KRAS_G12C PIK3CG 29 73 Primary -5.36 -12.48 -0.78 495.99 1.00 1250 29 73 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C PIK3CG 166 72 Metastasis 0.21 -0.43 0.69 1165.44 1.00 1159 158 64 8 FALSE 0.33
non-small cell lung cancer KRAS_G12C PIK3CG 292 108 Primary 0.36 -0.09 0.83 1148.45 1.00 1931 271 87 21 FALSE 0.92
colorectal cancer KRAS_G12C PIK3CG 66 107 Tumor Type:overall -5.17 -12.17 -0.57 457.58 1.01 2060 66 107 0 FALSE 1.05
non-small cell lung cancer KRAS_G12C PIK3CG 458 180 Tumor Type:overall 0.28 -0.34 0.86 1213.71 1.00 3090 429 151 29 FALSE 0.41
colorectal cancer KRAS_G12C MAP2K4 37 24 Metastasis -1.53 -5.18 0.66 1010.83 1.00 818 37 24 0 TRUE 0.49
colorectal cancer KRAS_G12C MAP2K4 29 39 Primary -0.97 -3.92 0.93 1329.42 1.00 1275 28 38 1 TRUE 0.38
colorectal cancer KRAS_G12C MAP2K4 66 63 Tumor Type:overall -1.19 -4.32 1.02 1276.71 1.00 2093 65 62 1 TRUE 0.42
colorectal cancer KRAS_G12C EGFR 45 16 Metastasis -4.88 -12.87 -0.23 1240.21 1.00 894 45 16 0 TRUE 0.87
colorectal cancer KRAS_G12C EGFR 32 50 Primary -4.91 -12.88 -0.35 1204.04 1.00 1420 32 50 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C EGFR 171 432 Metastasis -2.97 -3.73 -2.19 1545.80 1.00 925 165 426 6 TRUE 13.32
non-small cell lung cancer KRAS_G12C EGFR 300 610 Primary -3.25 -4.22 -2.49 1541.51 1.00 1562 297 607 3 TRUE 13.18
colorectal cancer KRAS_G12C EGFR 77 66 Tumor Type:overall -4.72 -12.45 -0.12 1223.59 1.00 2314 77 66 0 TRUE 0.87
non-small cell lung cancer KRAS_G12C EGFR 471 1042 Tumor Type:overall -3.11 -4.07 -2.27 1629.56 1.00 2487 462 1033 9 TRUE 10.10
colorectal cancer KRAS_G12C ARID1B 37 35 Metastasis -5.20 -12.19 -0.94 1023.14 1.00 811 37 35 0 TRUE 1.07
colorectal cancer KRAS_G12C ARID1B 29 105 Primary -5.27 -12.37 -1.10 976.64 1.00 1224 29 105 0 TRUE 1.12
non-small cell lung cancer KRAS_G12C ARID1B 167 55 Metastasis 0.26 -0.39 0.86 1149.14 1.00 1173 158 46 9 TRUE 0.37
non-small cell lung cancer KRAS_G12C ARID1B 289 56 Primary 0.07 -0.63 0.65 1067.08 1.00 1962 282 49 7 TRUE 0.08
colorectal cancer KRAS_G12C ARID1B 66 140 Tumor Type:overall -5.05 -11.76 -0.81 925.07 1.00 2035 66 140 0 TRUE 1.08
non-small cell lung cancer KRAS_G12C ARID1B 456 111 Tumor Type:overall 0.16 -0.73 0.97 1458.14 1.00 3135 440 95 16 TRUE 0.14
non-small cell lung cancer KRAS_G12C INSR 166 22 Metastasis -0.65 -1.91 0.37 698.04 1.00 1196 164 20 2 FALSE 0.61
non-small cell lung cancer KRAS_G12C INSR 289 33 Primary -0.71 -1.94 0.26 674.37 1.00 1981 287 31 2 FALSE 0.71
non-small cell lung cancer KRAS_G12C INSR 455 55 Tumor Type:overall -0.70 -2.06 0.33 757.62 1.00 3177 451 51 4 FALSE 0.61
non-small cell lung cancer KRAS_G12C NKX2-1 167 18 Metastasis 0.56 -0.31 1.38 1329.27 1.00 1203 163 14 4 TRUE 0.71
non-small cell lung cancer KRAS_G12C NKX2-1 291 57 Primary 0.53 -0.12 1.12 1345.14 1.00 1969 280 46 11 TRUE 1.03
non-small cell lung cancer KRAS_G12C NKX2-1 458 75 Tumor Type:overall 0.53 -0.45 1.55 1408.08 1.00 3172 443 60 15 TRUE 0.57
colorectal cancer KRAS_G12C ARID5B 37 15 Metastasis -4.78 -11.76 -0.19 1351.39 1.00 827 37 15 0 FALSE 0.97
colorectal cancer KRAS_G12C ARID5B 29 53 Primary -4.84 -11.75 -0.38 1302.78 1.00 1271 29 53 0 FALSE 0.96
colorectal cancer KRAS_G12C ARID5B 66 68 Tumor Type:overall -4.69 -11.47 -0.23 1274.29 1.00 2098 66 68 0 FALSE 0.95
non-small cell lung cancer KRAS_G12C WT1 166 28 Metastasis -0.51 -1.58 0.31 922.29 1.00 1191 164 26 2 TRUE 0.54
non-small cell lung cancer KRAS_G12C WT1 289 42 Primary -0.48 -1.44 0.30 775.21 1.00 1974 285 38 4 TRUE 0.54
non-small cell lung cancer KRAS_G12C WT1 455 70 Tumor Type:overall -0.49 -1.50 0.38 870.07 1.00 3165 449 64 6 TRUE 0.48
non-small cell lung cancer KRAS_G12C MET 171 56 Metastasis -1.15 -2.02 -0.38 1305.64 1.00 1211 169 54 2 TRUE 2.20
non-small cell lung cancer KRAS_G12C MET 300 109 Primary -1.09 -1.90 -0.42 1316.76 1.00 1981 294 103 6 TRUE 2.31
non-small cell lung cancer KRAS_G12C MET 471 165 Tumor Type:overall -1.12 -2.05 -0.32 1380.78 1.00 3192 463 157 8 TRUE 1.91
non-small cell lung cancer KRAS_G12C PMS1 166 23 Metastasis 0.02 -1.12 0.91 1225.53 1.01 1196 164 21 2 TRUE 0.01
non-small cell lung cancer KRAS_G12C PMS1 289 29 Primary 0.23 -0.68 1.05 1045.36 1.00 1986 283 23 6 TRUE 0.22
non-small cell lung cancer KRAS_G12C PMS1 455 52 Tumor Type:overall 0.13 -0.94 1.08 1159.64 1.00 3182 447 44 8 TRUE 0.09
non-small cell lung cancer KRAS_G12C PIK3C3 166 26 Metastasis -0.34 -1.31 0.29 12.94 1.11 1192 164 24 2 FALSE 0.36
non-small cell lung cancer KRAS_G12C PIK3C3 289 50 Primary -0.31 -1.17 0.32 13.27 1.10 1966 284 45 5 FALSE 0.36
non-small cell lung cancer KRAS_G12C PIK3C3 455 76 Tumor Type:overall -0.33 -1.23 0.31 16.15 1.10 3158 448 69 7 FALSE 0.34
colorectal cancer KRAS_G12C BRAF 45 79 Metastasis -6.01 -12.49 -1.75 139.00 1.02 832 45 79 0 TRUE 1.34
colorectal cancer KRAS_G12C BRAF 32 174 Primary -5.99 -12.26 -1.68 126.48 1.02 1301 32 174 0 TRUE 1.32
non-small cell lung cancer KRAS_G12C BRAF 171 72 Metastasis -1.33 -2.21 -0.58 956.35 1.00 1191 169 70 2 TRUE 2.81
non-small cell lung cancer KRAS_G12C BRAF 300 121 Primary -1.26 -2.08 -0.54 1102.03 1.00 1961 294 115 6 TRUE 3.02
colorectal cancer KRAS_G12C BRAF 77 253 Tumor Type:overall -5.86 -12.19 -1.57 118.82 1.03 2133 77 253 0 TRUE 1.31
non-small cell lung cancer KRAS_G12C BRAF 471 193 Tumor Type:overall -1.28 -2.15 -0.53 1156.43 1.00 3152 463 185 8 TRUE 2.63
colorectal cancer KRAS_G12C B2M 37 15 Metastasis -1.49 -6.22 0.92 1531.31 1.00 831 37 15 0 FALSE 0.38
colorectal cancer KRAS_G12C B2M 30 124 Primary -0.17 -1.55 1.02 1633.55 1.00 1236 27 121 3 FALSE 0.10
colorectal cancer KRAS_G12C B2M 67 139 Tumor Type:overall -0.72 -3.79 2.03 1423.65 1.00 2067 64 136 3 FALSE 0.20
colorectal cancer KRAS_G12C TGFBR1 37 13 Metastasis -0.55 -3.50 1.66 1415.04 1.00 831 36 12 1 FALSE 0.17
colorectal cancer KRAS_G12C TGFBR1 29 38 Primary -1.36 -5.08 0.95 1088.51 1.00 1278 29 38 0 FALSE 0.40
non-small cell lung cancer KRAS_G12C TGFBR1 166 23 Metastasis 0.68 -0.12 1.43 1210.48 1.00 1198 161 18 5 FALSE 1.12
non-small cell lung cancer KRAS_G12C TGFBR1 289 28 Primary 0.64 -0.09 1.33 1192.45 1.00 1987 283 22 6 FALSE 1.11
colorectal cancer KRAS_G12C TGFBR1 66 51 Tumor Type:overall -0.91 -4.16 1.50 1294.35 1.00 2109 65 50 1 FALSE 0.28
non-small cell lung cancer KRAS_G12C TGFBR1 455 51 Tumor Type:overall 0.67 -0.21 1.47 1223.53 1.00 3185 444 40 11 FALSE 0.95
colorectal cancer KRAS_G12C TET2 37 14 Metastasis -4.96 -11.59 -0.23 1423.13 1.00 829 37 14 0 TRUE 0.98
colorectal cancer KRAS_G12C TET2 29 77 Primary -5.02 -12.07 -0.58 1332.94 1.00 1250 29 77 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C TET2 166 38 Metastasis -0.57 -1.57 0.32 1015.66 1.00 1184 162 34 4 TRUE 0.60
non-small cell lung cancer KRAS_G12C TET2 289 43 Primary -0.77 -1.91 0.12 1096.30 1.00 1971 287 41 2 TRUE 0.87
colorectal cancer KRAS_G12C TET2 66 91 Tumor Type:overall -4.76 -11.37 -0.17 1346.22 1.00 2079 66 91 0 TRUE 0.96
non-small cell lung cancer KRAS_G12C TET2 455 81 Tumor Type:overall -0.68 -1.84 0.30 1129.80 1.00 3155 449 75 6 TRUE 0.63
colorectal cancer KRAS_G12C PDGFRB 29 46 Primary -0.50 -3.46 1.43 1295.62 1.00 1267 28 45 1 TRUE 0.16
non-small cell lung cancer KRAS_G12C PDGFRB 166 37 Metastasis 0.33 -0.32 0.92 779.82 1.00 1186 161 32 5 TRUE 0.52
non-small cell lung cancer KRAS_G12C PDGFRB 292 55 Primary 0.40 -0.17 0.97 845.12 1.00 1969 281 44 11 TRUE 0.76
colorectal cancer KRAS_G12C PDGFRB 29 46 Tumor Type:overall -0.38 -4.72 4.07 1342.94 1.00 1267 28 45 1 TRUE 0.06
non-small cell lung cancer KRAS_G12C PDGFRB 458 92 Tumor Type:overall 0.38 -0.26 1.10 872.25 1.00 3155 442 76 16 TRUE 0.53
colorectal cancer KRAS_G12C CARD11 37 29 Metastasis 0.16 -1.30 1.41 1573.93 1.00 817 35 27 2 FALSE 0.09
colorectal cancer KRAS_G12C CARD11 29 99 Primary -0.09 -1.47 1.02 1448.31 1.00 1224 27 97 2 FALSE 0.05
non-small cell lung cancer KRAS_G12C CARD11 166 43 Metastasis 0.46 -0.11 1.05 1204.39 1.00 1183 157 34 9 FALSE 0.96
non-small cell lung cancer KRAS_G12C CARD11 290 87 Primary 0.39 -0.15 0.85 1332.63 1.00 1941 276 73 14 FALSE 0.89
colorectal cancer KRAS_G12C CARD11 66 128 Tumor Type:overall 0.01 -2.04 1.85 1507.47 1.00 2041 62 124 4 FALSE 0.00
non-small cell lung cancer KRAS_G12C CARD11 456 130 Tumor Type:overall 0.42 -0.24 1.05 1371.17 1.00 3124 433 107 23 FALSE 0.67
colorectal cancer KRAS_G12C DNMT3A 37 11 Metastasis -4.96 -12.23 0.01 488.38 1.00 830 37 11 0 TRUE 0.90
colorectal cancer KRAS_G12C DNMT3A 29 45 Primary -4.97 -12.42 -0.16 452.94 1.00 1273 29 45 0 TRUE 0.91
non-small cell lung cancer KRAS_G12C DNMT3A 166 27 Metastasis 0.52 -0.21 1.13 1134.01 1.00 1193 162 23 4 TRUE 0.88
non-small cell lung cancer KRAS_G12C DNMT3A 289 50 Primary 0.62 0.01 1.19 1022.10 1.00 1972 277 38 12 TRUE 1.40
colorectal cancer KRAS_G12C DNMT3A 66 56 Tumor Type:overall -4.79 -11.64 0.06 390.50 1.00 2103 66 56 0 TRUE 0.90
non-small cell lung cancer KRAS_G12C DNMT3A 455 77 Tumor Type:overall 0.57 -0.14 1.20 1041.24 1.00 3165 439 61 16 TRUE 0.96
colorectal cancer KRAS_G12C MSH6 37 23 Metastasis -5.12 -11.96 -0.47 394.70 1.01 821 37 23 0 TRUE 1.03
colorectal cancer KRAS_G12C MSH6 29 77 Primary -5.16 -12.01 -0.76 306.36 1.01 1250 29 77 0 TRUE 1.03
colorectal cancer KRAS_G12C MSH6 66 100 Tumor Type:overall -4.96 -11.59 -0.54 295.76 1.01 2071 66 100 0 TRUE 1.04
non-small cell lung cancer KRAS_G12C MAX 166 16 Metastasis 0.86 0.07 1.62 1024.17 1.00 1204 162 12 4 FALSE 1.64
non-small cell lung cancer KRAS_G12C MAX 290 39 Primary 0.88 0.24 1.50 1095.30 1.00 1980 280 29 10 FALSE 2.21
non-small cell lung cancer KRAS_G12C MAX 456 55 Tumor Type:overall 0.88 0.08 1.67 1066.19 1.00 3184 442 41 14 FALSE 1.46
non-small cell lung cancer KRAS_G12C INPP4B 167 53 Metastasis 0.83 0.32 1.42 1388.26 1.00 1182 152 38 15 FALSE 2.48
non-small cell lung cancer KRAS_G12C INPP4B 290 73 Primary 0.57 -0.03 1.05 1179.99 1.00 1953 278 61 12 FALSE 1.41
non-small cell lung cancer KRAS_G12C INPP4B 457 126 Tumor Type:overall 0.69 -0.04 1.38 1467.92 1.00 3135 430 99 27 FALSE 1.08
non-small cell lung cancer KRAS_G12C NFE2L2 167 43 Metastasis -0.17 -1.01 0.68 1042.78 1.00 1184 160 36 7 FALSE 0.15
non-small cell lung cancer KRAS_G12C NFE2L2 289 81 Primary -0.63 -1.59 0.14 830.48 1.01 1940 285 77 4 FALSE 0.80
non-small cell lung cancer KRAS_G12C NFE2L2 456 124 Tumor Type:overall -0.40 -1.42 0.53 945.18 1.00 3124 445 113 11 FALSE 0.36
colorectal cancer KRAS_G12C SOX9 38 72 Metastasis 0.36 -0.68 1.27 1415.68 1.00 779 33 67 5 FALSE 0.34
colorectal cancer KRAS_G12C SOX9 30 192 Primary -0.04 -1.09 0.83 1563.15 1.00 1141 26 188 4 FALSE 0.03
colorectal cancer KRAS_G12C SOX9 68 264 Tumor Type:overall 0.15 -1.22 1.60 1517.65 1.00 1920 59 255 9 FALSE 0.08
colorectal cancer KRAS_G12C ETV1 37 14 Metastasis -4.70 -12.35 0.03 1400.58 1.00 827 37 14 0 TRUE 0.88
colorectal cancer KRAS_G12C ETV1 29 38 Primary -4.68 -12.54 -0.07 1386.95 1.00 1277 29 38 0 TRUE 0.86
colorectal cancer KRAS_G12C ETV1 66 52 Tumor Type:overall -4.60 -12.28 0.08 1415.03 1.00 2104 66 52 0 TRUE 0.87
colorectal cancer KRAS_G12C ARAF 37 18 Metastasis -1.66 -4.71 1.07 4.47 1.54 824 36 17 1 FALSE 0.41
colorectal cancer KRAS_G12C ARAF 29 37 Primary -2.07 -4.71 0.86 7.32 1.30 1280 29 37 0 FALSE 0.55
non-small cell lung cancer KRAS_G12C ARAF 166 30 Metastasis -0.46 -2.26 0.60 1043.08 1.00 1191 165 29 1 FALSE 0.28
non-small cell lung cancer KRAS_G12C ARAF 290 39 Primary 0.21 -0.66 1.03 748.58 1.00 1982 282 31 8 FALSE 0.20
colorectal cancer KRAS_G12C ARAF 66 55 Tumor Type:overall -1.84 -4.70 1.13 5.23 1.44 2104 65 54 1 FALSE 0.47
non-small cell lung cancer KRAS_G12C ARAF 456 69 Tumor Type:overall -0.11 -1.61 1.04 1374.21 1.00 3173 447 60 9 FALSE 0.06
non-small cell lung cancer KRAS_G12C JAK2 171 41 Metastasis -0.42 -1.57 0.44 1058.10 1.00 1226 168 38 3 TRUE 0.39
non-small cell lung cancer KRAS_G12C JAK2 300 37 Primary -0.18 -1.09 0.62 970.05 1.00 2041 295 32 5 TRUE 0.16
non-small cell lung cancer KRAS_G12C JAK2 471 78 Tumor Type:overall -0.28 -1.51 0.88 1058.54 1.00 3267 463 70 8 TRUE 0.20
colorectal cancer KRAS_G12C SMAD2 37 26 Metastasis 0.63 -0.70 1.70 1457.52 1.00 819 35 24 2 TRUE 0.51
colorectal cancer KRAS_G12C SMAD2 29 76 Primary 0.84 -0.28 1.76 1496.61 1.00 1249 25 72 4 TRUE 0.95
colorectal cancer KRAS_G12C SMAD2 66 102 Tumor Type:overall 0.72 -0.80 2.23 1495.71 1.00 2068 60 96 6 TRUE 0.46
non-small cell lung cancer KRAS_G12C TP63 166 33 Metastasis -0.26 -1.12 0.59 1075.32 1.00 1187 162 29 4 FALSE 0.25
non-small cell lung cancer KRAS_G12C TP63 289 39 Primary -0.40 -1.44 0.42 954.35 1.00 1975 286 36 3 FALSE 0.40
non-small cell lung cancer KRAS_G12C TP63 455 72 Tumor Type:overall -0.32 -1.32 0.67 1128.47 1.00 3162 448 65 7 FALSE 0.28
colorectal cancer KRAS_G12C JUN 37 16 Metastasis -4.51 -11.93 -0.30 442.32 1.00 826 37 16 0 FALSE 0.85
colorectal cancer KRAS_G12C JUN 29 37 Primary -4.50 -11.69 -0.22 503.49 1.00 1277 29 37 0 FALSE 0.84
colorectal cancer KRAS_G12C JUN 66 53 Tumor Type:overall -4.41 -11.73 0.01 448.79 1.00 2103 66 53 0 FALSE 0.84
colorectal cancer KRAS_G12C DNMT3B 37 15 Metastasis -4.79 -12.06 -0.26 917.75 1.00 827 37 15 0 FALSE 0.88
colorectal cancer KRAS_G12C DNMT3B 29 49 Primary -4.88 -12.22 -0.35 984.56 1.00 1269 29 49 0 FALSE 0.89
colorectal cancer KRAS_G12C DNMT3B 66 64 Tumor Type:overall -4.66 -11.80 0.03 1000.07 1.00 2096 66 64 0 FALSE 0.87
non-small cell lung cancer KRAS_G12C MYOD1 166 25 Metastasis -0.15 -1.15 0.64 955.20 1.00 1193 164 23 2 FALSE 0.13
non-small cell lung cancer KRAS_G12C MYOD1 289 33 Primary -0.06 -0.93 0.67 1047.64 1.00 1985 284 28 5 FALSE 0.06
non-small cell lung cancer KRAS_G12C MYOD1 455 58 Tumor Type:overall -0.11 -1.16 0.73 1050.60 1.00 3178 448 51 7 FALSE 0.09
colorectal cancer KRAS_G12C FGFR1 45 17 Metastasis -4.61 -11.45 -0.08 1298.59 1.00 893 45 17 0 TRUE 0.91
colorectal cancer KRAS_G12C FGFR1 32 34 Primary -4.60 -11.57 -0.07 1289.05 1.00 1435 32 34 0 TRUE 0.89
colorectal cancer KRAS_G12C FGFR1 77 51 Tumor Type:overall -4.50 -11.14 -0.06 1297.31 1.00 2328 77 51 0 TRUE 0.89
colorectal cancer KRAS_G12C MITF 37 14 Metastasis 1.27 -0.30 2.67 1390.42 1.00 830 34 11 3 FALSE 1.01
colorectal cancer KRAS_G12C MITF 29 38 Primary -0.78 -5.97 1.32 1103.01 1.00 1274 29 38 0 FALSE 0.16
colorectal cancer KRAS_G12C MITF 66 52 Tumor Type:overall 0.27 -3.29 2.50 1207.08 1.00 2104 63 49 3 FALSE 0.07
non-small cell lung cancer KRAS_G12C BTK 166 28 Metastasis 0.43 -0.41 1.18 1090.57 1.00 1194 160 22 6 TRUE 0.55
non-small cell lung cancer KRAS_G12C BTK 289 32 Primary 0.25 -0.71 0.99 772.80 1.00 1982 285 28 4 TRUE 0.25
non-small cell lung cancer KRAS_G12C BTK 455 60 Tumor Type:overall 0.33 -0.62 1.20 1134.46 1.00 3176 445 50 10 TRUE 0.30
colorectal cancer KRAS_G12C SH2B3 26 46 Primary -5.27 -14.61 0.03 1138.84 1.00 1165 26 46 0 FALSE 0.59
colorectal cancer KRAS_G12C SH2B3 26 46 Tumor Type:overall -3.82 -11.36 2.84 994.60 1.01 1165 26 46 0 FALSE 0.54
colorectal cancer KRAS_G12C GLI1 33 24 Metastasis -4.95 -12.29 -0.57 763.78 1.00 735 33 24 0 FALSE 0.95
colorectal cancer KRAS_G12C GLI1 26 63 Primary -4.96 -12.25 -0.56 717.89 1.00 1150 26 63 0 FALSE 0.96
non-small cell lung cancer KRAS_G12C GLI1 155 37 Metastasis 0.68 0.13 1.26 1189.82 1.00 1057 145 27 10 FALSE 1.80
non-small cell lung cancer KRAS_G12C GLI1 267 69 Primary 0.55 -0.05 1.05 879.98 1.00 1761 255 57 12 FALSE 1.34
colorectal cancer KRAS_G12C GLI1 59 87 Tumor Type:overall -4.83 -11.82 -0.20 722.90 1.00 1885 59 87 0 FALSE 0.96
non-small cell lung cancer KRAS_G12C GLI1 422 106 Tumor Type:overall 0.61 0.01 1.20 1181.82 1.00 2818 400 84 22 FALSE 1.39
colorectal cancer KRAS_G12C ZFHX3 33 52 Metastasis -1.97 -4.81 0.12 1465.64 1.00 721 32 51 1 FALSE 0.94
colorectal cancer KRAS_G12C ZFHX3 26 174 Primary -2.87 -6.84 -0.60 1394.82 1.00 1085 26 174 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C ZFHX3 153 75 Metastasis -0.38 -1.29 0.25 996.96 1.00 1014 148 70 5 FALSE 0.48
non-small cell lung cancer KRAS_G12C ZFHX3 268 89 Primary 0.01 -0.56 0.59 917.82 1.00 1743 254 75 14 FALSE 0.01
colorectal cancer KRAS_G12C ZFHX3 59 226 Tumor Type:overall -2.31 -5.76 0.15 1464.80 1.00 1806 58 225 1 FALSE 0.92
non-small cell lung cancer KRAS_G12C ZFHX3 421 164 Tumor Type:overall -0.20 -1.32 0.66 1132.03 1.00 2757 402 145 19 FALSE 0.16
colorectal cancer KRAS_G12C MST1R 33 19 Metastasis -4.90 -11.60 -0.30 744.26 1.00 741 33 19 0 FALSE 0.97
colorectal cancer KRAS_G12C MST1R 26 54 Primary -4.88 -11.71 -0.42 730.96 1.00 1162 26 54 0 FALSE 0.99
colorectal cancer KRAS_G12C MST1R 59 73 Tumor Type:overall -4.75 -11.46 -0.18 739.73 1.00 1903 59 73 0 FALSE 0.97
colorectal cancer KRAS_G12C MGA 33 29 Metastasis -0.90 -2.69 0.87 26.00 1.11 730 32 28 1 FALSE 0.43
colorectal cancer KRAS_G12C MGA 26 94 Primary -1.05 -2.95 0.54 44.58 1.06 1128 25 93 1 FALSE 0.58
non-small cell lung cancer KRAS_G12C MGA 156 82 Metastasis 0.62 0.18 1.13 950.99 1.00 1033 137 63 19 FALSE 2.06
non-small cell lung cancer KRAS_G12C MGA 268 115 Primary 0.46 0.00 0.83 579.80 1.00 1724 249 96 19 FALSE 1.45
colorectal cancer KRAS_G12C MGA 59 123 Tumor Type:overall -0.95 -3.10 0.99 60.88 1.05 1858 57 121 2 FALSE 0.43
non-small cell lung cancer KRAS_G12C MGA 424 197 Tumor Type:overall 0.55 0.02 1.13 1283.31 1.00 2757 386 159 38 FALSE 1.23
colorectal cancer KRAS_G12C TCF3 33 13 Metastasis -4.78 -12.22 0.06 1291.02 1.00 746 33 13 0 FALSE 0.85
colorectal cancer KRAS_G12C TCF3 26 55 Primary -4.85 -12.16 -0.31 1280.92 1.00 1155 26 55 0 FALSE 0.90
colorectal cancer KRAS_G12C TCF3 59 68 Tumor Type:overall -4.64 -11.72 0.03 1266.83 1.00 1901 59 68 0 FALSE 0.88
non-small cell lung cancer KRAS_G12C KMT2B 87 19 Metastasis 0.26 -0.52 1.08 1013.21 1.00 575 83 15 4 FALSE 0.29
non-small cell lung cancer KRAS_G12C KMT2B 151 52 Primary 0.18 -0.56 0.82 760.86 1.00 1010 144 45 7 FALSE 0.21
non-small cell lung cancer KRAS_G12C KMT2B 238 71 Tumor Type:overall 0.21 -0.83 1.19 1260.32 1.00 1585 227 60 11 FALSE 0.17
colorectal cancer KRAS_G12C TCF7L2 33 97 Metastasis -0.34 -1.83 0.57 59.78 1.06 670 31 95 2 FALSE 0.24
colorectal cancer KRAS_G12C TCF7L2 26 202 Primary 0.29 -0.62 1.19 1215.38 1.00 1030 19 195 7 FALSE 0.29
colorectal cancer KRAS_G12C TCF7L2 59 299 Tumor Type:overall -0.01 -1.68 1.44 1427.32 1.00 1700 50 290 9 FALSE 0.01
colorectal cancer KRAS_G12C ANKRD11 33 36 Metastasis -5.24 -12.22 -0.84 1282.37 1.00 731 33 36 0 FALSE 1.09
colorectal cancer KRAS_G12C ANKRD11 26 110 Primary -5.36 -12.62 -1.07 1265.30 1.00 1121 26 110 0 FALSE 1.13
non-small cell lung cancer KRAS_G12C ANKRD11 153 27 Metastasis -0.42 -1.89 0.47 1037.67 1.00 1059 152 26 1 FALSE 0.33
non-small cell lung cancer KRAS_G12C ANKRD11 267 45 Primary -0.14 -1.00 0.64 1001.37 1.00 1778 260 38 7 FALSE 0.14
colorectal cancer KRAS_G12C ANKRD11 59 146 Tumor Type:overall -5.17 -12.03 -0.78 1313.85 1.00 1852 59 146 0 FALSE 1.09
non-small cell lung cancer KRAS_G12C ANKRD11 420 72 Tumor Type:overall -0.28 -1.42 0.63 1153.52 1.00 2837 412 64 8 FALSE 0.23
colorectal cancer KRAS_G12C PGR 33 11 Metastasis -4.77 -12.50 0.08 1124.16 1.00 748 33 11 0 FALSE 0.82
colorectal cancer KRAS_G12C PGR 26 52 Primary -4.89 -12.77 -0.30 1088.20 1.00 1158 26 52 0 FALSE 0.87
non-small cell lung cancer KRAS_G12C PGR 153 34 Metastasis 0.62 -0.04 1.19 853.14 1.00 1054 147 28 6 FALSE 1.31
non-small cell lung cancer KRAS_G12C PGR 268 53 Primary 0.69 0.13 1.22 921.14 1.00 1777 255 40 13 FALSE 1.85
colorectal cancer KRAS_G12C PGR 59 63 Tumor Type:overall -4.57 -11.99 0.30 1110.58 1.00 1906 59 63 0 FALSE 0.82
non-small cell lung cancer KRAS_G12C PGR 421 87 Tumor Type:overall 0.66 -0.01 1.27 1149.56 1.00 2831 402 68 19 FALSE 1.18
colorectal cancer KRAS_G12C PLCG2 33 22 Metastasis -0.45 -2.41 1.15 1346.78 1.00 739 32 21 1 FALSE 0.20
colorectal cancer KRAS_G12C PLCG2 26 63 Primary -0.55 -2.45 0.86 1020.14 1.00 1149 25 62 1 FALSE 0.27
non-small cell lung cancer KRAS_G12C PLCG2 153 24 Metastasis 0.26 -0.68 1.32 906.38 1.01 1065 147 18 6 FALSE 0.22
non-small cell lung cancer KRAS_G12C PLCG2 267 38 Primary -0.30 -1.56 0.54 309.29 1.01 1785 265 36 2 FALSE 0.23
colorectal cancer KRAS_G12C PLCG2 59 85 Tumor Type:overall -0.48 -2.64 1.29 1227.43 1.00 1888 57 83 2 FALSE 0.20
non-small cell lung cancer KRAS_G12C PLCG2 420 62 Tumor Type:overall -0.04 -1.30 1.11 1503.06 1.00 2850 412 54 8 FALSE 0.02
colorectal cancer KRAS_G12C POLD1 33 20 Metastasis -1.06 -4.26 1.12 1153.37 1.00 743 32 19 1 TRUE 0.37
colorectal cancer KRAS_G12C POLD1 26 92 Primary -2.35 -6.64 0.14 1307.92 1.00 1136 26 92 0 TRUE 0.71
non-small cell lung cancer KRAS_G12C POLD1 153 25 Metastasis -0.51 -1.64 0.44 739.20 1.00 1058 151 23 2 TRUE 0.49
non-small cell lung cancer KRAS_G12C POLD1 267 33 Primary -0.50 -1.58 0.40 679.60 1.00 1787 264 30 3 TRUE 0.52
colorectal cancer KRAS_G12C POLD1 59 112 Tumor Type:overall -1.63 -5.18 1.03 1474.98 1.00 1879 58 111 1 TRUE 0.53
non-small cell lung cancer KRAS_G12C POLD1 420 58 Tumor Type:overall -0.51 -1.70 0.49 770.03 1.00 2845 415 53 5 TRUE 0.44
colorectal cancer KRAS_G12C INHBA 33 20 Metastasis -0.87 -4.09 1.14 709.50 1.00 739 32 19 1 FALSE 0.31
colorectal cancer KRAS_G12C INHBA 26 34 Primary -1.33 -5.03 0.95 1096.12 1.00 1172 26 34 0 FALSE 0.44
non-small cell lung cancer KRAS_G12C INHBA 153 32 Metastasis 0.13 -0.77 0.78 911.90 1.00 1057 150 29 3 FALSE 0.13
non-small cell lung cancer KRAS_G12C INHBA 267 55 Primary 0.29 -0.35 0.88 778.00 1.00 1773 256 44 11 FALSE 0.44
colorectal cancer KRAS_G12C INHBA 59 54 Tumor Type:overall -1.07 -4.40 1.18 886.75 1.00 1911 58 53 1 FALSE 0.36
non-small cell lung cancer KRAS_G12C INHBA 420 87 Tumor Type:overall 0.20 -0.59 0.91 1086.94 1.00 2830 406 73 14 FALSE 0.20
non-small cell lung cancer KRAS_G12C PREX2 88 42 Metastasis 0.72 0.04 1.45 1220.44 1.00 563 76 30 12 FALSE 1.30
non-small cell lung cancer KRAS_G12C PREX2 151 63 Primary 0.18 -0.62 0.80 1359.00 1.00 1001 144 56 7 FALSE 0.21
non-small cell lung cancer KRAS_G12C PREX2 239 105 Tumor Type:overall 0.44 -0.65 1.41 1234.38 1.00 1564 220 86 19 FALSE 0.38
colorectal cancer KRAS_G12C AMER1 37 51 Metastasis 0.62 -0.52 1.56 1425.68 1.00 797 32 46 5 FALSE 0.60
colorectal cancer KRAS_G12C AMER1 29 118 Primary -0.54 -2.48 0.74 1540.98 1.00 1206 28 117 1 FALSE 0.29
non-small cell lung cancer KRAS_G12C AMER1 168 54 Metastasis 0.83 0.38 1.31 1379.18 1.00 1183 154 40 14 FALSE 3.41
non-small cell lung cancer KRAS_G12C AMER1 289 95 Primary 0.78 0.37 1.17 1368.33 1.00 1947 268 74 21 FALSE 3.89
colorectal cancer KRAS_G12C AMER1 66 169 Tumor Type:overall 0.00 -1.95 1.59 1473.80 1.00 2003 60 163 6 FALSE 0.00
non-small cell lung cancer KRAS_G12C AMER1 457 149 Tumor Type:overall 0.81 0.28 1.31 1512.43 1.00 3130 422 114 35 FALSE 2.53
colorectal cancer KRAS_G12C HLA-A 26 42 Primary -5.10 -14.44 0.21 739.06 1.00 1170 26 42 0 FALSE 0.57
colorectal cancer KRAS_G12C HLA-A 26 42 Tumor Type:overall -3.72 -11.51 2.73 920.84 1.00 1170 26 42 0 FALSE 0.54
colorectal cancer KRAS_G12C EPHA7 33 23 Metastasis -5.11 -12.05 -0.40 1075.93 1.00 735 33 23 0 FALSE 0.97
colorectal cancer KRAS_G12C EPHA7 26 67 Primary -5.06 -12.12 -0.65 1015.68 1.00 1149 26 67 0 FALSE 0.99
non-small cell lung cancer KRAS_G12C EPHA7 153 54 Metastasis 0.30 -0.31 0.97 494.53 1.01 1041 142 43 11 FALSE 0.43
non-small cell lung cancer KRAS_G12C EPHA7 267 75 Primary 0.03 -0.64 0.55 1202.14 1.00 1752 259 67 8 FALSE 0.03
colorectal cancer KRAS_G12C EPHA7 59 90 Tumor Type:overall -4.92 -11.81 -0.45 1101.44 1.00 1884 59 90 0 FALSE 0.96
non-small cell lung cancer KRAS_G12C EPHA7 420 129 Tumor Type:overall 0.17 -0.55 0.86 1380.67 1.00 2793 401 110 19 FALSE 0.16
colorectal cancer KRAS_G12C NCOA3 33 14 Metastasis -1.44 -5.29 0.98 1542.13 1.00 745 33 14 0 TRUE 0.42
colorectal cancer KRAS_G12C NCOA3 26 42 Primary -0.80 -3.66 1.12 1201.95 1.00 1166 25 41 1 TRUE 0.29
colorectal cancer KRAS_G12C NCOA3 59 56 Tumor Type:overall -1.09 -4.52 1.35 1396.41 1.00 1911 58 55 1 TRUE 0.35
non-small cell lung cancer KRAS_G12C DROSHA 87 19 Metastasis 0.20 -0.68 0.98 1192.22 1.00 573 83 15 4 FALSE 0.19
non-small cell lung cancer KRAS_G12C DROSHA 151 35 Primary 0.10 -0.80 0.85 719.80 1.00 1022 147 31 4 FALSE 0.10
non-small cell lung cancer KRAS_G12C DROSHA 238 54 Tumor Type:overall 0.15 -0.78 1.00 1228.05 1.00 1595 230 46 8 FALSE 0.13
cancer of unknown primary KRAS_G12D SPEN 43 50 Metastasis 0.06 -0.98 1.15 25.97 1.07 613 39 46 4 FALSE 0.04
colorectal cancer KRAS_G12D SPEN 111 45 Metastasis 0.00 -0.70 0.63 532.89 1.01 737 105 39 6 FALSE 0.00
colorectal cancer KRAS_G12D SPEN 181 110 Primary -0.01 -0.56 0.52 340.50 1.01 1096 167 96 14 FALSE 0.01
non-small cell lung cancer KRAS_G12D SPEN 45 71 Metastasis -1.20 -3.21 0.37 1572.37 1.00 1295 44 70 1 FALSE 0.71
non-small cell lung cancer KRAS_G12D SPEN 106 50 Primary -1.22 -3.21 0.33 1463.08 1.00 2147 105 49 1 FALSE 0.73
uterine cancer KRAS_G12D SPEN 21 38 Metastasis 0.77 -0.11 1.63 737.46 1.00 335 16 33 5 FALSE 1.08
uterine cancer KRAS_G12D SPEN 31 82 Primary 0.58 -0.26 1.34 538.28 1.01 599 26 77 5 FALSE 0.79
cancer of unknown primary KRAS_G12D SPEN 43 50 Tumor Type:overall -0.01 -4.12 4.17 1175.46 1.01 613 39 46 4 FALSE 0.00
colorectal cancer KRAS_G12D SPEN 292 155 Tumor Type:overall 0.00 -0.84 0.83 1081.86 1.01 1833 272 135 20 FALSE 0.00
non-small cell lung cancer KRAS_G12D SPEN 151 121 Tumor Type:overall -1.18 -3.28 0.64 1475.85 1.00 3442 149 119 2 FALSE 0.62
uterine cancer KRAS_G12D SPEN 52 120 Tumor Type:overall 0.68 -0.24 1.63 744.12 1.00 934 42 110 10 FALSE 0.74
colorectal cancer KRAS_G12D KMT2C 112 49 Metastasis -0.41 -1.30 0.35 1407.24 1.00 728 108 45 4 FALSE 0.48
colorectal cancer KRAS_G12D KMT2C 183 149 Primary -0.16 -0.69 0.32 1427.83 1.00 1076 165 131 18 FALSE 0.28
non-small cell lung cancer KRAS_G12D KMT2C 45 89 Metastasis -0.70 -1.85 0.31 1368.76 1.00 1259 43 87 2 FALSE 0.71
non-small cell lung cancer KRAS_G12D KMT2C 106 133 Primary -0.77 -1.87 0.10 1394.41 1.00 2071 103 130 3 FALSE 0.88
colorectal cancer KRAS_G12D KMT2C 295 198 Tumor Type:overall -0.28 -1.43 0.81 1541.16 1.00 1804 273 176 22 FALSE 0.19
non-small cell lung cancer KRAS_G12D KMT2C 151 222 Tumor Type:overall -0.73 -1.95 0.33 1203.36 1.00 3330 146 217 5 FALSE 0.71
appendiceal cancer KRAS_G12D TP53 29 30 Metastasis 0.62 -0.14 1.48 1421.36 1.00 54 16 17 13 TRUE 0.88
appendiceal cancer KRAS_G12D TP53 27 21 Primary 0.26 -0.79 1.10 1174.48 1.00 34 20 14 7 TRUE 0.23
cancer of unknown primary KRAS_G12D TP53 43 392 Metastasis 0.11 -0.49 0.72 1418.91 1.00 329 20 369 23 TRUE 0.14
cancer of unknown primary KRAS_G12D TP53 7 28 Primary 0.85 -0.30 2.38 1419.08 1.00 42 2 23 5 TRUE 0.67
colorectal cancer KRAS_G12D TP53 135 701 Metastasis -0.48 -0.81 -0.19 1608.07 1.00 238 52 618 83 TRUE 2.75
colorectal cancer KRAS_G12D TP53 217 1018 Primary -0.51 -0.78 -0.25 1376.68 1.00 465 100 901 117 TRUE 3.94
non-small cell lung cancer KRAS_G12D TP53 47 855 Metastasis -0.98 -1.50 -0.46 1559.54 1.00 594 30 838 17 TRUE 3.78
non-small cell lung cancer KRAS_G12D TP53 109 1201 Primary -0.98 -1.38 -0.60 1586.44 1.00 1190 80 1172 29 TRUE 6.18
pancreatic cancer KRAS_G12D TP53 209 379 Metastasis 1.12 0.81 1.51 1200.09 1.00 185 41 211 168 TRUE 9.62
pancreatic cancer KRAS_G12D TP53 287 567 Primary 0.88 0.57 1.16 1479.88 1.00 284 77 357 210 TRUE 8.40
uterine cancer KRAS_G12D TP53 18 180 Metastasis -1.13 -2.05 -0.42 239.66 1.01 219 15 177 3 TRUE 2.04
uterine cancer KRAS_G12D TP53 33 361 Primary -1.07 -1.86 -0.41 260.04 1.01 415 25 353 8 TRUE 2.32
appendiceal cancer KRAS_G12D TP53 56 51 Tumor Type:overall 0.41 -0.81 1.45 1420.49 1.00 88 36 31 20 TRUE 0.35
cancer of unknown primary KRAS_G12D TP53 50 420 Tumor Type:overall 0.47 -1.02 2.13 1375.86 1.00 371 22 392 28 TRUE 0.27
colorectal cancer KRAS_G12D TP53 352 1719 Tumor Type:overall -0.49 -0.97 0.06 1634.67 1.00 703 152 1519 200 TRUE 1.08
non-small cell lung cancer KRAS_G12D TP53 156 2056 Tumor Type:overall -0.97 -1.74 -0.10 1651.32 1.00 1784 110 2010 46 TRUE 1.56
pancreatic cancer KRAS_G12D TP53 496 946 Tumor Type:overall 0.99 0.38 1.53 1557.55 1.00 469 118 568 378 TRUE 2.57
uterine cancer KRAS_G12D TP53 51 541 Tumor Type:overall -1.09 -2.03 -0.34 413.28 1.01 634 40 530 11 TRUE 1.82
colorectal cancer KRAS_G12D ATRX 111 33 Metastasis -0.28 -1.12 0.51 926.28 1.00 742 107 29 4 TRUE 0.29
colorectal cancer KRAS_G12D ATRX 180 86 Primary -0.37 -1.10 0.29 620.70 1.00 1099 172 78 8 TRUE 0.52
non-small cell lung cancer KRAS_G12D ATRX 45 79 Metastasis 0.28 -0.51 1.15 699.12 1.00 1274 40 74 5 TRUE 0.31
non-small cell lung cancer KRAS_G12D ATRX 106 129 Primary 0.02 -0.74 0.65 924.04 1.01 2085 101 124 5 TRUE 0.02
uterine cancer KRAS_G12D ATRX 18 48 Metastasis -0.36 -2.03 1.10 1094.08 1.00 325 15 45 3 TRUE 0.19
uterine cancer KRAS_G12D ATRX 30 128 Primary -2.46 -6.97 -0.36 1401.47 1.00 585 30 128 0 TRUE 0.73
colorectal cancer KRAS_G12D ATRX 291 119 Tumor Type:overall -0.31 -1.29 0.65 1357.14 1.00 1841 279 107 12 TRUE 0.27
non-small cell lung cancer KRAS_G12D ATRX 151 208 Tumor Type:overall 0.14 -0.86 1.09 1408.72 1.00 3359 141 198 10 TRUE 0.11
uterine cancer KRAS_G12D ATRX 48 176 Tumor Type:overall -1.34 -4.38 0.94 1501.41 1.00 910 45 173 3 TRUE 0.51
colorectal cancer KRAS_G12D ATR 111 30 Metastasis -0.57 -1.73 0.37 1449.80 1.00 747 109 28 2 FALSE 0.57
colorectal cancer KRAS_G12D ATR 182 84 Primary -0.35 -1.04 0.28 1565.63 1.00 1106 173 75 9 FALSE 0.51
non-small cell lung cancer KRAS_G12D ATR 45 53 Metastasis -0.48 -1.96 0.64 1181.69 1.00 1287 44 52 1 FALSE 0.33
non-small cell lung cancer KRAS_G12D ATR 106 76 Primary -0.38 -1.60 0.61 1133.42 1.00 2122 103 73 3 FALSE 0.30
uterine cancer KRAS_G12D ATR 19 24 Metastasis -0.02 -1.35 1.31 914.32 1.00 347 17 22 2 FALSE 0.01
uterine cancer KRAS_G12D ATR 30 74 Primary -0.34 -1.62 0.73 987.43 1.00 601 28 72 2 FALSE 0.24
colorectal cancer KRAS_G12D ATR 293 114 Tumor Type:overall -0.46 -1.72 0.64 1396.92 1.00 1853 282 103 11 FALSE 0.36
non-small cell lung cancer KRAS_G12D ATR 151 129 Tumor Type:overall -0.42 -1.78 0.78 1301.30 1.00 3409 147 125 4 FALSE 0.27
uterine cancer KRAS_G12D ATR 49 98 Tumor Type:overall -0.16 -1.63 1.17 1063.94 1.00 948 45 94 4 FALSE 0.09
colorectal cancer KRAS_G12D PDGFRA 128 15 Metastasis -0.25 -1.83 0.74 340.51 1.01 812 127 14 1 TRUE 0.15
colorectal cancer KRAS_G12D PDGFRA 204 45 Primary 0.14 -0.74 0.93 362.60 1.00 1260 196 37 8 TRUE 0.13
non-small cell lung cancer KRAS_G12D PDGFRA 47 64 Metastasis -0.89 -2.52 0.33 1028.09 1.01 1325 46 63 1 TRUE 0.69
non-small cell lung cancer KRAS_G12D PDGFRA 109 84 Primary -0.88 -2.32 0.30 1140.66 1.00 2188 107 82 2 TRUE 0.72
colorectal cancer KRAS_G12D PDGFRA 332 60 Tumor Type:overall -0.07 -1.54 1.15 640.44 1.00 2072 323 51 9 TRUE 0.04
non-small cell lung cancer KRAS_G12D PDGFRA 156 148 Tumor Type:overall -0.88 -2.45 0.42 1049.48 1.00 3513 153 145 3 TRUE 0.64
colorectal cancer KRAS_G12D FBXW7 133 90 Metastasis 0.59 0.08 1.09 1413.55 1.00 763 112 69 21 TRUE 1.66
colorectal cancer KRAS_G12D FBXW7 212 249 Primary 0.18 -0.19 0.55 1448.50 1.00 1106 174 211 38 TRUE 0.46
non-small cell lung cancer KRAS_G12D FBXW7 47 32 Metastasis -1.21 -3.98 0.44 1097.27 1.00 1355 47 32 0 TRUE 0.42
non-small cell lung cancer KRAS_G12D FBXW7 109 54 Primary -0.83 -2.53 0.54 477.70 1.00 2216 107 52 2 TRUE 0.51
uterine cancer KRAS_G12D FBXW7 20 38 Metastasis 1.34 0.30 2.38 1472.53 1.00 349 13 31 7 TRUE 1.85
uterine cancer KRAS_G12D FBXW7 32 107 Primary 0.40 -0.60 1.28 1512.34 1.00 646 27 102 5 TRUE 0.41
colorectal cancer KRAS_G12D FBXW7 345 339 Tumor Type:overall 0.41 -0.65 1.49 1508.97 1.00 1869 286 280 59 TRUE 0.36
non-small cell lung cancer KRAS_G12D FBXW7 156 86 Tumor Type:overall -0.99 -3.19 0.64 710.75 1.00 3571 154 84 2 TRUE 0.47
uterine cancer KRAS_G12D FBXW7 52 145 Tumor Type:overall 0.82 -0.74 2.29 1409.31 1.00 995 40 133 12 TRUE 0.57
colorectal cancer KRAS_G12D MAP3K1 111 30 Metastasis -0.40 -1.28 0.41 1115.72 1.00 742 108 27 3 FALSE 0.45
colorectal cancer KRAS_G12D MAP3K1 180 62 Primary -0.40 -1.25 0.32 988.91 1.00 1113 174 56 6 FALSE 0.51
non-small cell lung cancer KRAS_G12D MAP3K1 45 30 Metastasis -0.94 -4.18 0.71 980.49 1.00 1308 45 30 0 FALSE 0.35
non-small cell lung cancer KRAS_G12D MAP3K1 106 37 Primary -0.47 -2.40 0.86 998.56 1.01 2158 104 35 2 FALSE 0.25
uterine cancer KRAS_G12D MAP3K1 19 16 Metastasis 0.83 -0.77 2.34 1347.00 1.00 347 16 13 3 FALSE 0.54
uterine cancer KRAS_G12D MAP3K1 30 55 Primary -0.42 -2.29 0.91 1469.39 1.00 600 29 54 1 FALSE 0.21
colorectal cancer KRAS_G12D MAP3K1 291 92 Tumor Type:overall -0.39 -1.30 0.43 1348.83 1.00 1855 282 83 9 FALSE 0.39
non-small cell lung cancer KRAS_G12D MAP3K1 151 67 Tumor Type:overall -0.70 -3.10 1.00 1203.09 1.01 3466 149 65 2 FALSE 0.29
uterine cancer KRAS_G12D MAP3K1 49 71 Tumor Type:overall 0.21 -1.94 2.22 1010.55 1.00 947 45 67 4 FALSE 0.08
colorectal cancer KRAS_G12D NSD1 111 23 Metastasis -0.20 -1.50 0.95 1229.44 1.00 750 107 19 4 FALSE 0.12
colorectal cancer KRAS_G12D NSD1 180 63 Primary -1.20 -2.57 -0.15 1198.01 1.00 1111 178 61 2 FALSE 1.26
non-small cell lung cancer KRAS_G12D NSD1 45 34 Metastasis -3.74 -11.86 0.39 2.98 1.39 1304 45 34 0 FALSE 0.52
non-small cell lung cancer KRAS_G12D NSD1 106 56 Primary -3.75 -11.80 0.33 2.92 1.40 2136 106 56 0 FALSE 0.54
uterine cancer KRAS_G12D NSD1 19 32 Metastasis 0.31 -0.85 1.44 1256.65 1.00 337 16 29 3 FALSE 0.23
uterine cancer KRAS_G12D NSD1 32 91 Primary 0.07 -0.95 0.98 1112.05 1.00 588 28 87 4 FALSE 0.05
colorectal cancer KRAS_G12D NSD1 291 86 Tumor Type:overall -0.68 -2.43 1.10 1358.67 1.00 1861 285 80 6 FALSE 0.38
non-small cell lung cancer KRAS_G12D NSD1 151 90 Tumor Type:overall -3.69 -11.67 0.29 2.91 1.41 3440 151 90 0 FALSE 0.54
uterine cancer KRAS_G12D NSD1 51 123 Tumor Type:overall 0.18 -1.03 1.45 1191.44 1.00 925 44 116 7 FALSE 0.11
colorectal cancer KRAS_G12D FLT4 111 41 Metastasis -0.11 -0.73 0.57 1309.35 1.01 733 106 36 5 TRUE 0.15
colorectal cancer KRAS_G12D FLT4 182 98 Primary -0.08 -0.56 0.46 49.89 1.05 1089 169 85 13 TRUE 0.13
non-small cell lung cancer KRAS_G12D FLT4 45 37 Metastasis -0.63 -2.61 1.00 752.23 1.00 1303 43 35 2 TRUE 0.29
non-small cell lung cancer KRAS_G12D FLT4 106 65 Primary -1.64 -5.25 0.16 1265.76 1.00 2130 106 65 0 TRUE 0.65
uterine cancer KRAS_G12D FLT4 30 43 Primary -0.21 -2.08 1.17 1024.91 1.00 613 28 41 2 TRUE 0.10
colorectal cancer KRAS_G12D FLT4 293 139 Tumor Type:overall -0.08 -0.80 0.71 1327.50 1.01 1822 275 121 18 TRUE 0.09
non-small cell lung cancer KRAS_G12D FLT4 151 102 Tumor Type:overall -1.11 -3.59 0.70 1378.51 1.00 3433 149 100 2 TRUE 0.49
uterine cancer KRAS_G12D FLT4 30 43 Tumor Type:overall -0.21 -4.80 4.17 1413.88 1.00 613 28 41 2 TRUE 0.04
cancer of unknown primary KRAS_G12D PTPRD 42 51 Metastasis -1.67 -4.45 0.23 1371.53 1.00 614 41 50 1 FALSE 0.78
colorectal cancer KRAS_G12D PTPRD 111 28 Metastasis -0.39 -1.36 0.52 1406.30 1.00 746 108 25 3 FALSE 0.39
colorectal cancer KRAS_G12D PTPRD 180 75 Primary -0.40 -1.21 0.30 1484.45 1.00 1109 173 68 7 FALSE 0.55
non-small cell lung cancer KRAS_G12D PTPRD 45 165 Metastasis -0.22 -1.42 0.49 43.18 1.08 1205 42 162 3 FALSE 0.18
non-small cell lung cancer KRAS_G12D PTPRD 106 226 Primary 0.15 -0.49 0.68 103.94 1.04 2009 93 213 13 FALSE 0.20
uterine cancer KRAS_G12D PTPRD 18 25 Metastasis -1.67 -4.54 0.54 1052.61 1.00 344 17 24 1 FALSE 0.72
uterine cancer KRAS_G12D PTPRD 30 74 Primary -2.30 -5.52 -0.28 850.80 1.00 602 30 74 0 FALSE 1.01
cancer of unknown primary KRAS_G12D PTPRD 42 51 Tumor Type:overall -1.49 -5.84 2.88 1588.30 1.00 614 41 50 1 FALSE 0.31
colorectal cancer KRAS_G12D PTPRD 291 103 Tumor Type:overall -0.38 -1.41 0.68 1249.62 1.00 1855 281 93 10 FALSE 0.29
non-small cell lung cancer KRAS_G12D PTPRD 151 391 Tumor Type:overall -0.02 -1.11 0.79 139.78 1.03 3214 135 375 16 FALSE 0.01
uterine cancer KRAS_G12D PTPRD 48 99 Tumor Type:overall -1.94 -4.91 0.23 1223.18 1.00 946 47 98 1 FALSE 0.86
colorectal cancer KRAS_G12D RET 128 20 Metastasis -1.41 -3.99 -0.13 1156.36 1.00 806 128 20 0 TRUE 0.78
colorectal cancer KRAS_G12D RET 204 45 Primary -0.95 -2.06 0.07 530.56 1.00 1254 200 41 4 TRUE 1.05
non-small cell lung cancer KRAS_G12D RET 47 39 Metastasis -0.82 -2.61 0.63 268.26 1.01 1346 46 38 1 TRUE 0.51
non-small cell lung cancer KRAS_G12D RET 109 54 Primary -0.91 -2.60 0.47 216.52 1.01 2215 108 53 1 TRUE 0.62
colorectal cancer KRAS_G12D RET 332 65 Tumor Type:overall -1.16 -2.91 0.19 1101.66 1.00 2060 328 61 4 TRUE 0.82
non-small cell lung cancer KRAS_G12D RET 156 93 Tumor Type:overall -0.86 -2.60 0.64 250.04 1.01 3561 154 91 2 TRUE 0.53
colorectal cancer KRAS_G12D KDM5A 113 24 Metastasis -0.42 -1.51 0.62 1184.44 1.00 753 110 21 3 FALSE 0.36
colorectal cancer KRAS_G12D KDM5A 180 72 Primary -0.69 -1.60 0.11 1269.63 1.00 1102 175 67 5 FALSE 0.97
non-small cell lung cancer KRAS_G12D KDM5A 45 24 Metastasis -1.35 -4.27 0.92 1301.49 1.00 1314 44 23 1 FALSE 0.52
non-small cell lung cancer KRAS_G12D KDM5A 106 49 Primary -1.92 -5.22 0.17 1288.06 1.00 2147 106 49 0 FALSE 0.71
uterine cancer KRAS_G12D KDM5A 18 23 Metastasis -0.58 -2.39 0.93 501.00 1.00 340 17 22 1 FALSE 0.29
uterine cancer KRAS_G12D KDM5A 30 42 Primary -0.63 -2.49 0.80 515.44 1.00 616 29 41 1 FALSE 0.33
colorectal cancer KRAS_G12D KDM5A 293 96 Tumor Type:overall -0.56 -1.90 0.75 1308.29 1.00 1855 285 88 8 FALSE 0.41
non-small cell lung cancer KRAS_G12D KDM5A 151 73 Tumor Type:overall -1.61 -4.51 0.68 1368.88 1.00 3461 150 72 1 FALSE 0.62
uterine cancer KRAS_G12D KDM5A 48 65 Tumor Type:overall -0.61 -2.46 0.83 530.51 1.00 956 46 63 2 FALSE 0.31
colorectal cancer KRAS_G12D PIK3C2G 111 20 Metastasis -1.22 -3.36 0.47 1531.85 1.00 752 109 18 2 FALSE 0.68
colorectal cancer KRAS_G12D PIK3C2G 180 67 Primary -3.13 -7.39 -1.17 1087.82 1.00 1105 180 67 0 FALSE 1.27
non-small cell lung cancer KRAS_G12D PIK3C2G 45 52 Metastasis -0.81 -4.10 0.58 982.56 1.00 1288 45 52 0 FALSE 0.31
non-small cell lung cancer KRAS_G12D PIK3C2G 106 79 Primary -0.02 -1.03 0.89 1074.58 1.00 2123 101 74 5 FALSE 0.01
colorectal cancer KRAS_G12D PIK3C2G 291 87 Tumor Type:overall -2.01 -5.03 0.54 1433.14 1.00 1857 289 85 2 FALSE 0.83
non-small cell lung cancer KRAS_G12D PIK3C2G 151 131 Tumor Type:overall -0.41 -2.51 0.96 886.55 1.00 3411 146 126 5 FALSE 0.18
non-small cell lung cancer KRAS_G12D TSHR 45 34 Metastasis -0.78 -4.51 0.94 1194.29 1.00 1305 45 34 0 TRUE 0.23
non-small cell lung cancer KRAS_G12D TSHR 107 35 Primary 0.10 -1.30 1.34 891.38 1.00 2160 104 32 3 TRUE 0.05
non-small cell lung cancer KRAS_G12D TSHR 152 69 Tumor Type:overall -0.33 -2.79 1.47 1314.14 1.00 3465 149 66 3 TRUE 0.12
cancer of unknown primary KRAS_G12D CREBBP 42 52 Metastasis -0.70 -2.58 0.63 1401.64 1.00 611 40 50 2 TRUE 0.41
colorectal cancer KRAS_G12D CREBBP 111 37 Metastasis -2.53 -7.42 -0.38 1444.40 1.00 738 111 37 0 TRUE 0.81
colorectal cancer KRAS_G12D CREBBP 187 151 Primary -0.18 -0.70 0.37 1517.71 1.00 1059 168 132 19 TRUE 0.31
non-small cell lung cancer KRAS_G12D CREBBP 45 67 Metastasis -0.64 -2.16 0.55 1235.89 1.00 1279 44 66 1 TRUE 0.46
non-small cell lung cancer KRAS_G12D CREBBP 106 75 Primary -0.44 -1.65 0.57 1103.04 1.00 2122 103 72 3 TRUE 0.35
uterine cancer KRAS_G12D CREBBP 18 26 Metastasis -0.98 -2.82 0.64 1343.28 1.00 340 17 25 1 TRUE 0.57
uterine cancer KRAS_G12D CREBBP 30 69 Primary -1.12 -2.92 0.31 1314.79 1.00 596 29 68 1 TRUE 0.75
cancer of unknown primary KRAS_G12D CREBBP 42 52 Tumor Type:overall -0.54 -4.78 3.86 1460.40 1.00 611 40 50 2 TRUE 0.10
colorectal cancer KRAS_G12D CREBBP 298 188 Tumor Type:overall -1.21 -4.34 1.10 1414.07 1.00 1797 279 169 19 TRUE 0.44
non-small cell lung cancer KRAS_G12D CREBBP 151 142 Tumor Type:overall -0.55 -2.01 0.81 1365.65 1.00 3401 147 138 4 TRUE 0.36
uterine cancer KRAS_G12D CREBBP 48 95 Tumor Type:overall -1.03 -3.02 0.70 1208.36 1.00 936 46 93 2 TRUE 0.57
non-small cell lung cancer KRAS_G12D BRIP1 45 30 Metastasis -1.73 -4.84 0.22 1510.29 1.00 1307 45 30 0 TRUE 0.50
non-small cell lung cancer KRAS_G12D BRIP1 106 40 Primary -1.48 -4.06 0.27 1270.09 1.00 2154 105 39 1 TRUE 0.71
non-small cell lung cancer KRAS_G12D BRIP1 151 70 Tumor Type:overall -1.60 -4.34 0.38 1241.39 1.00 3461 150 69 1 TRUE 0.70
colorectal cancer KRAS_G12D AXIN2 111 26 Metastasis -0.57 -1.78 0.40 1458.97 1.00 745 109 24 2 TRUE 0.51
colorectal cancer KRAS_G12D AXIN2 180 89 Primary -0.40 -1.12 0.26 1526.65 1.00 1096 171 80 9 TRUE 0.58
non-small cell lung cancer KRAS_G12D AXIN2 45 26 Metastasis -0.02 -1.65 1.31 1389.67 1.00 1312 44 25 1 TRUE 0.01
non-small cell lung cancer KRAS_G12D AXIN2 106 36 Primary 0.02 -1.51 1.15 1458.77 1.00 2158 104 34 2 TRUE 0.01
uterine cancer KRAS_G12D AXIN2 18 15 Metastasis -0.28 -3.02 1.21 853.10 1.00 346 18 15 0 TRUE 0.09
uterine cancer KRAS_G12D AXIN2 30 37 Primary 0.22 -1.17 1.35 1156.06 1.00 614 27 34 3 TRUE 0.13
colorectal cancer KRAS_G12D AXIN2 291 115 Tumor Type:overall -0.46 -1.77 0.75 1572.72 1.00 1841 280 104 11 TRUE 0.32
non-small cell lung cancer KRAS_G12D AXIN2 151 62 Tumor Type:overall 0.01 -1.71 1.31 1217.19 1.00 3470 148 59 3 TRUE 0.01
uterine cancer KRAS_G12D AXIN2 48 52 Tumor Type:overall -0.02 -2.03 1.38 857.03 1.00 960 45 49 3 TRUE 0.01
colorectal cancer KRAS_G12D DOT1L 111 23 Metastasis -0.72 -2.20 0.29 1539.88 1.00 749 110 22 1 FALSE 0.56
colorectal cancer KRAS_G12D DOT1L 181 61 Primary -0.37 -1.22 0.40 1523.06 1.00 1114 174 54 7 FALSE 0.42
non-small cell lung cancer KRAS_G12D DOT1L 45 46 Metastasis 0.36 -0.78 1.38 822.91 1.00 1295 42 43 3 FALSE 0.30
non-small cell lung cancer KRAS_G12D DOT1L 106 61 Primary 0.18 -0.87 1.02 1276.50 1.00 2136 103 58 3 FALSE 0.15
colorectal cancer KRAS_G12D DOT1L 292 84 Tumor Type:overall -0.53 -1.93 0.67 1638.58 1.00 1863 284 76 8 FALSE 0.37
non-small cell lung cancer KRAS_G12D DOT1L 151 107 Tumor Type:overall 0.25 -0.89 1.36 1246.59 1.00 3431 145 101 6 FALSE 0.17
colorectal cancer KRAS_G12D PTPRS 111 63 Metastasis -1.17 -2.68 -0.12 1453.32 1.00 715 109 61 2 FALSE 1.14
colorectal cancer KRAS_G12D PTPRS 187 191 Primary 0.09 -0.33 0.50 1515.83 1.00 1032 158 162 29 FALSE 0.16
non-small cell lung cancer KRAS_G12D PTPRS 45 32 Metastasis -1.13 -4.25 0.77 24.46 1.09 1311 44 31 1 FALSE 0.37
non-small cell lung cancer KRAS_G12D PTPRS 106 48 Primary -1.49 -4.93 0.73 22.07 1.11 2145 106 48 0 FALSE 0.46
colorectal cancer KRAS_G12D PTPRS 298 254 Tumor Type:overall -0.52 -2.32 0.96 1495.07 1.00 1747 267 223 31 FALSE 0.29
non-small cell lung cancer KRAS_G12D PTPRS 151 80 Tumor Type:overall -1.26 -4.56 0.85 23.18 1.10 3456 150 79 1 FALSE 0.39
cancer of unknown primary KRAS_G12D SMARCA4 42 62 Metastasis -0.37 -1.87 0.74 338.98 1.01 596 39 59 3 FALSE 0.23
colorectal cancer KRAS_G12D SMARCA4 111 40 Metastasis -1.19 -3.09 0.05 1363.66 1.00 734 110 39 1 FALSE 0.80
colorectal cancer KRAS_G12D SMARCA4 183 129 Primary 0.11 -0.40 0.62 1507.15 1.00 1080 163 109 20 FALSE 0.16
non-small cell lung cancer KRAS_G12D SMARCA4 46 149 Metastasis 0.15 -0.63 0.86 1375.47 1.00 1203 40 143 6 FALSE 0.16
non-small cell lung cancer KRAS_G12D SMARCA4 106 164 Primary 0.16 -0.53 0.78 1516.90 1.00 2049 97 155 9 FALSE 0.20
uterine cancer KRAS_G12D SMARCA4 18 31 Metastasis -0.04 -1.23 1.03 431.39 1.02 340 16 29 2 FALSE 0.03
uterine cancer KRAS_G12D SMARCA4 32 71 Primary -0.10 -1.09 0.90 458.08 1.01 594 29 68 3 FALSE 0.07
cancer of unknown primary KRAS_G12D SMARCA4 42 62 Tumor Type:overall -0.38 -4.69 3.76 1464.65 1.00 596 39 59 3 FALSE 0.07
colorectal cancer KRAS_G12D SMARCA4 294 169 Tumor Type:overall -0.53 -2.62 1.02 1441.85 1.00 1814 273 148 21 FALSE 0.25
non-small cell lung cancer KRAS_G12D SMARCA4 152 313 Tumor Type:overall 0.14 -0.97 1.09 1333.28 1.00 3252 137 298 15 FALSE 0.10
uterine cancer KRAS_G12D SMARCA4 50 102 Tumor Type:overall -0.08 -1.27 1.03 674.06 1.01 934 45 97 5 FALSE 0.05
cancer of unknown primary KRAS_G12D PTPRT 42 55 Metastasis -0.78 -2.50 0.58 1419.02 1.00 611 40 53 2 FALSE 0.50
colorectal cancer KRAS_G12D PTPRT 111 58 Metastasis -0.92 -2.27 -0.11 1242.91 1.00 715 109 56 2 FALSE 1.04
colorectal cancer KRAS_G12D PTPRT 181 127 Primary -0.40 -0.98 0.16 1341.96 1.00 1063 167 113 14 FALSE 0.79
non-small cell lung cancer KRAS_G12D PTPRT 46 150 Metastasis -0.24 -1.08 0.47 249.22 1.01 1220 42 146 4 FALSE 0.26
non-small cell lung cancer KRAS_G12D PTPRT 108 201 Primary -0.20 -0.88 0.38 116.86 1.03 2029 100 193 8 FALSE 0.25
uterine cancer KRAS_G12D PTPRT 18 24 Metastasis -0.89 -3.05 0.60 1553.69 1.00 343 17 23 1 FALSE 0.50
uterine cancer KRAS_G12D PTPRT 30 63 Primary -1.05 -3.08 0.35 1390.83 1.00 596 29 62 1 FALSE 0.65
cancer of unknown primary KRAS_G12D PTPRT 42 55 Tumor Type:overall -0.61 -4.91 3.60 1620.70 1.00 611 40 53 2 FALSE 0.12
colorectal cancer KRAS_G12D PTPRT 292 185 Tumor Type:overall -0.65 -1.92 0.30 1452.91 1.00 1778 276 169 16 FALSE 0.60
non-small cell lung cancer KRAS_G12D PTPRT 154 351 Tumor Type:overall -0.23 -1.16 0.54 358.39 1.02 3249 142 339 12 FALSE 0.22
uterine cancer KRAS_G12D PTPRT 48 87 Tumor Type:overall -0.95 -3.03 0.64 1424.41 1.00 939 46 85 2 FALSE 0.53
colorectal cancer KRAS_G12D HGF 111 22 Metastasis -0.18 -1.17 0.65 1149.69 1.00 747 109 20 2 FALSE 0.15
colorectal cancer KRAS_G12D HGF 180 34 Primary -0.11 -1.03 0.70 1130.08 1.00 1136 175 29 5 FALSE 0.10
non-small cell lung cancer KRAS_G12D HGF 45 72 Metastasis 0.04 -0.95 1.05 1471.85 1.00 1271 41 68 4 FALSE 0.03
non-small cell lung cancer KRAS_G12D HGF 106 119 Primary -0.33 -1.34 0.48 1533.41 1.00 2087 103 116 3 FALSE 0.32
colorectal cancer KRAS_G12D HGF 291 56 Tumor Type:overall -0.15 -1.16 0.69 1220.02 1.00 1883 284 49 7 FALSE 0.12
non-small cell lung cancer KRAS_G12D HGF 151 191 Tumor Type:overall -0.13 -1.26 0.92 1431.33 1.00 3358 144 184 7 FALSE 0.08
colorectal cancer KRAS_G12D BLM 111 14 Metastasis -2.07 -5.89 -0.16 1431.92 1.00 757 111 14 0 TRUE 0.83
colorectal cancer KRAS_G12D BLM 180 56 Primary -1.33 -2.84 -0.22 1523.79 1.00 1112 177 53 3 TRUE 1.35
colorectal cancer KRAS_G12D BLM 291 70 Tumor Type:overall -1.59 -4.12 0.42 1350.43 1.00 1869 288 67 3 TRUE 0.82
cancer of unknown primary KRAS_G12D PIK3CA 42 89 Metastasis -0.15 -1.25 0.78 1346.53 1.00 588 37 84 5 TRUE 0.12
colorectal cancer KRAS_G12D PIK3CA 130 151 Metastasis 0.52 0.09 0.94 1390.27 1.00 713 99 120 31 TRUE 1.74
colorectal cancer KRAS_G12D PIK3CA 209 360 Primary 0.23 -0.09 0.54 1333.89 1.00 1030 154 305 55 TRUE 0.81
non-small cell lung cancer KRAS_G12D PIK3CA 47 80 Metastasis 0.22 -0.63 0.99 1382.12 1.00 1311 43 76 4 TRUE 0.22
non-small cell lung cancer KRAS_G12D PIK3CA 109 162 Primary 0.11 -0.63 0.74 1258.78 1.00 2117 101 154 8 TRUE 0.12
uterine cancer KRAS_G12D PIK3CA 20 153 Metastasis 0.70 -0.18 1.50 1379.97 1.00 257 11 144 9 TRUE 0.99
uterine cancer KRAS_G12D PIK3CA 38 404 Primary 1.28 0.62 2.14 1542.53 1.00 463 8 374 30 TRUE 3.20
cancer of unknown primary KRAS_G12D PIK3CA 42 89 Tumor Type:overall -0.17 -4.47 4.20 1310.05 1.00 588 37 84 5 TRUE 0.03
colorectal cancer KRAS_G12D PIK3CA 339 511 Tumor Type:overall 0.35 -0.61 1.21 1255.23 1.00 1743 253 425 86 TRUE 0.35
non-small cell lung cancer KRAS_G12D PIK3CA 156 242 Tumor Type:overall 0.15 -0.77 1.03 1495.61 1.00 3428 144 230 12 TRUE 0.13
uterine cancer KRAS_G12D PIK3CA 58 557 Tumor Type:overall 0.99 -0.28 2.28 1513.89 1.00 720 19 518 39 TRUE 0.93
non-small cell lung cancer KRAS_G12D GATA3 45 26 Metastasis -1.09 -3.82 0.62 67.09 1.04 1313 44 25 1 FALSE 0.47
non-small cell lung cancer KRAS_G12D GATA3 106 40 Primary -1.47 -4.97 0.12 27.94 1.06 2155 106 40 0 FALSE 0.55
non-small cell lung cancer KRAS_G12D GATA3 151 66 Tumor Type:overall -1.27 -4.35 0.42 42.28 1.05 3468 150 65 1 FALSE 0.52
colorectal cancer KRAS_G12D ESR1 111 22 Metastasis -0.33 -1.35 0.50 1226.96 1.00 747 109 20 2 TRUE 0.31
colorectal cancer KRAS_G12D ESR1 180 50 Primary -0.24 -1.03 0.50 1409.56 1.00 1120 174 44 6 TRUE 0.27
non-small cell lung cancer KRAS_G12D ESR1 45 17 Metastasis -0.36 -2.34 1.30 1434.42 1.00 1322 44 16 1 TRUE 0.16
non-small cell lung cancer KRAS_G12D ESR1 106 39 Primary -0.53 -2.36 0.87 1248.70 1.00 2156 105 38 1 TRUE 0.27
colorectal cancer KRAS_G12D ESR1 291 72 Tumor Type:overall -0.28 -1.25 0.62 1266.57 1.00 1867 283 64 8 TRUE 0.23
non-small cell lung cancer KRAS_G12D ESR1 151 56 Tumor Type:overall -0.45 -2.38 1.21 1318.46 1.00 3478 149 54 2 TRUE 0.20
colorectal cancer KRAS_G12D ALK 128 37 Metastasis -0.68 -1.50 0.08 1011.33 1.00 792 125 34 3 TRUE 1.02
colorectal cancer KRAS_G12D ALK 204 78 Primary -0.66 -1.45 0.04 1084.63 1.00 1236 198 72 6 TRUE 1.11
non-small cell lung cancer KRAS_G12D ALK 47 67 Metastasis -1.03 -4.09 0.30 1150.69 1.00 1322 47 67 0 TRUE 0.43
non-small cell lung cancer KRAS_G12D ALK 109 102 Primary -0.36 -1.42 0.63 1068.45 1.01 2173 104 97 5 TRUE 0.31
uterine cancer KRAS_G12D ALK 18 15 Metastasis -1.51 -4.66 0.56 972.52 1.00 369 18 15 0 TRUE 0.56
uterine cancer KRAS_G12D ALK 32 38 Primary -1.32 -4.06 0.55 749.54 1.00 706 31 37 1 TRUE 0.58
colorectal cancer KRAS_G12D ALK 332 115 Tumor Type:overall -0.67 -1.56 0.18 1226.33 1.00 2028 323 106 9 TRUE 0.88
non-small cell lung cancer KRAS_G12D ALK 156 169 Tumor Type:overall -0.65 -2.69 0.69 1418.04 1.00 3495 151 164 5 TRUE 0.36
uterine cancer KRAS_G12D ALK 50 53 Tumor Type:overall -1.39 -4.33 0.70 867.63 1.00 1075 49 52 1 TRUE 0.56
colorectal cancer KRAS_G12D RNF43 112 64 Metastasis -0.38 -1.17 0.30 1512.33 1.00 722 106 58 6 TRUE 0.50
colorectal cancer KRAS_G12D RNF43 187 203 Primary -0.24 -0.71 0.19 1464.94 1.00 1028 164 180 23 TRUE 0.53
pancreatic cancer KRAS_G12D RNF43 202 28 Metastasis 0.25 -0.57 0.88 233.54 1.02 360 193 19 9 TRUE 0.29
pancreatic cancer KRAS_G12D RNF43 282 52 Primary 0.65 0.12 1.17 920.19 1.00 589 256 26 26 TRUE 1.82
uterine cancer KRAS_G12D RNF43 19 22 Metastasis 0.47 -0.72 1.55 1113.16 1.00 340 17 20 2 TRUE 0.38
uterine cancer KRAS_G12D RNF43 32 73 Primary 0.44 -0.48 1.25 895.21 1.00 589 27 68 5 TRUE 0.46
colorectal cancer KRAS_G12D RNF43 299 267 Tumor Type:overall -0.32 -1.40 0.80 1289.49 1.00 1750 270 238 29 TRUE 0.24
pancreatic cancer KRAS_G12D RNF43 484 80 Tumor Type:overall 0.44 -0.47 1.17 764.08 1.00 949 449 45 35 TRUE 0.49
uterine cancer KRAS_G12D RNF43 51 95 Tumor Type:overall 0.47 -0.86 1.76 1121.69 1.00 929 44 88 7 TRUE 0.32
non-small cell lung cancer KRAS_G12D U2AF1 46 30 Metastasis 0.93 -0.28 2.09 1464.43 1.00 1311 42 26 4 FALSE 0.91
non-small cell lung cancer KRAS_G12D U2AF1 106 48 Primary 0.31 -0.96 1.29 1428.69 1.00 2147 104 46 2 FALSE 0.24
non-small cell lung cancer KRAS_G12D U2AF1 152 78 Tumor Type:overall 0.60 -0.87 1.85 1496.76 1.00 3458 146 72 6 FALSE 0.39
colorectal cancer KRAS_G12D LATS1 111 15 Metastasis -0.85 -2.24 0.42 1228.71 1.00 754 110 14 1 FALSE 0.68
colorectal cancer KRAS_G12D LATS1 180 40 Primary -0.79 -1.95 0.23 1325.88 1.00 1129 177 37 3 FALSE 0.80
non-small cell lung cancer KRAS_G12D LATS1 45 28 Metastasis -0.49 -2.61 0.95 431.23 1.00 1310 44 27 1 FALSE 0.23
non-small cell lung cancer KRAS_G12D LATS1 106 40 Primary -0.61 -2.50 0.74 388.67 1.00 2154 105 39 1 FALSE 0.31
colorectal cancer KRAS_G12D LATS1 291 55 Tumor Type:overall -0.82 -2.31 0.53 1227.42 1.00 1883 287 51 4 FALSE 0.56
non-small cell lung cancer KRAS_G12D LATS1 151 68 Tumor Type:overall -0.55 -2.61 0.86 469.19 1.00 3464 149 66 2 FALSE 0.26
colorectal cancer KRAS_G12D LATS2 111 27 Metastasis 0.07 -0.72 0.83 1300.61 1.00 744 107 23 4 FALSE 0.06
colorectal cancer KRAS_G12D LATS2 180 43 Primary 0.05 -0.71 0.78 1361.13 1.00 1127 174 37 6 FALSE 0.05
non-small cell lung cancer KRAS_G12D LATS2 45 23 Metastasis -0.95 -3.87 0.60 19.15 1.07 1315 44 22 1 FALSE 0.38
non-small cell lung cancer KRAS_G12D LATS2 106 38 Primary -1.30 -4.88 0.22 8.19 1.13 2157 106 38 0 FALSE 0.45
colorectal cancer KRAS_G12D LATS2 291 70 Tumor Type:overall 0.06 -0.78 0.86 1355.71 1.00 1871 281 60 10 FALSE 0.05
non-small cell lung cancer KRAS_G12D LATS2 151 61 Tumor Type:overall -1.11 -4.08 0.47 11.29 1.10 3472 150 60 1 FALSE 0.43
colorectal cancer KRAS_G12D PTEN 128 43 Metastasis -0.68 -1.70 0.13 1519.51 1.00 791 125 40 3 TRUE 0.81
colorectal cancer KRAS_G12D PTEN 206 142 Primary -0.44 -1.03 0.10 1465.11 1.00 1203 192 128 14 TRUE 0.90
non-small cell lung cancer KRAS_G12D PTEN 47 51 Metastasis -0.82 -2.37 0.44 1121.50 1.00 1336 46 50 1 TRUE 0.60
non-small cell lung cancer KRAS_G12D PTEN 109 85 Primary -0.84 -2.28 0.30 1185.98 1.00 2186 107 83 2 TRUE 0.70
uterine cancer KRAS_G12D PTEN 23 160 Metastasis 0.89 0.14 1.62 1391.28 1.00 282 11 148 12 TRUE 1.80
uterine cancer KRAS_G12D PTEN 50 467 Primary 1.15 0.60 1.74 1391.75 1.00 466 12 429 38 TRUE 4.01
colorectal cancer KRAS_G12D PTEN 334 185 Tumor Type:overall -0.54 -1.69 0.62 1545.30 1.00 1994 317 168 17 TRUE 0.47
non-small cell lung cancer KRAS_G12D PTEN 156 136 Tumor Type:overall -0.83 -2.47 0.54 1513.78 1.00 3522 153 133 3 TRUE 0.57
uterine cancer KRAS_G12D PTEN 73 627 Tumor Type:overall 1.02 0.00 2.00 1583.75 1.00 748 23 577 50 TRUE 1.37
colorectal cancer KRAS_G12D BCOR 111 18 Metastasis -0.31 -1.61 0.83 1260.22 1.00 752 109 16 2 FALSE 0.21
colorectal cancer KRAS_G12D BCOR 180 94 Primary -0.19 -0.84 0.42 1647.43 1.00 1094 169 83 11 FALSE 0.25
non-small cell lung cancer KRAS_G12D BCOR 45 54 Metastasis -0.17 -1.72 0.89 1319.87 1.00 1288 44 53 1 FALSE 0.10
non-small cell lung cancer KRAS_G12D BCOR 106 80 Primary 0.08 -0.96 0.91 1588.30 1.00 2124 101 75 5 FALSE 0.06
uterine cancer KRAS_G12D BCOR 18 45 Metastasis 0.81 -0.06 1.61 1292.05 1.00 326 14 41 4 FALSE 1.32
uterine cancer KRAS_G12D BCOR 30 95 Primary 0.82 0.08 1.52 1169.16 1.00 574 22 87 8 FALSE 1.59
colorectal cancer KRAS_G12D BCOR 291 112 Tumor Type:overall -0.25 -1.87 1.36 1249.77 1.00 1846 278 99 13 FALSE 0.12
non-small cell lung cancer KRAS_G12D BCOR 151 134 Tumor Type:overall -0.03 -1.39 0.98 1414.91 1.00 3412 145 128 6 FALSE 0.02
uterine cancer KRAS_G12D BCOR 48 140 Tumor Type:overall 0.82 -0.11 1.64 1138.75 1.00 900 36 128 12 FALSE 1.14
colorectal cancer KRAS_G12D CTNNB1 129 44 Metastasis 0.34 -0.30 0.94 1458.04 1.00 789 121 36 8 TRUE 0.56
colorectal cancer KRAS_G12D CTNNB1 206 119 Primary 0.44 -0.02 0.90 1541.98 1.00 1202 183 96 23 TRUE 1.20
non-small cell lung cancer KRAS_G12D CTNNB1 47 55 Metastasis -0.23 -1.52 0.84 965.94 1.01 1332 45 53 2 TRUE 0.16
non-small cell lung cancer KRAS_G12D CTNNB1 110 66 Primary -0.34 -1.63 0.59 681.44 1.02 2201 108 64 2 TRUE 0.27
uterine cancer KRAS_G12D CTNNB1 18 64 Metastasis -0.87 -2.39 0.39 1348.86 1.00 319 16 62 2 TRUE 0.66
uterine cancer KRAS_G12D CTNNB1 32 79 Primary -1.15 -2.89 0.19 1280.92 1.00 660 31 78 1 TRUE 0.87
colorectal cancer KRAS_G12D CTNNB1 335 163 Tumor Type:overall 0.40 -0.46 1.28 1660.66 1.00 1991 304 132 31 TRUE 0.41
non-small cell lung cancer KRAS_G12D CTNNB1 157 121 Tumor Type:overall -0.26 -1.63 0.95 1178.83 1.01 3533 153 117 4 TRUE 0.17
uterine cancer KRAS_G12D CTNNB1 50 143 Tumor Type:overall -1.01 -2.65 0.47 1338.37 1.00 979 47 140 3 TRUE 0.67
cancer of unknown primary KRAS_G12D ARID1A 43 109 Metastasis -0.01 -0.84 0.76 394.28 1.02 576 36 102 7 TRUE 0.01
colorectal cancer KRAS_G12D ARID1A 111 73 Metastasis -0.61 -1.46 0.07 1673.57 1.00 721 106 68 5 TRUE 0.93
colorectal cancer KRAS_G12D ARID1A 190 242 Primary -0.20 -0.64 0.22 1615.69 1.00 1011 161 213 29 TRUE 0.44
non-small cell lung cancer KRAS_G12D ARID1A 45 129 Metastasis -0.70 -1.90 0.24 1343.87 1.00 1224 43 127 2 TRUE 0.70
non-small cell lung cancer KRAS_G12D ARID1A 106 155 Primary -0.55 -1.41 0.20 1478.29 1.00 2053 101 150 5 TRUE 0.70
pancreatic cancer KRAS_G12D ARID1A 203 58 Metastasis 0.54 0.14 0.99 380.08 1.02 350 175 30 28 TRUE 1.82
pancreatic cancer KRAS_G12D ARID1A 282 69 Primary 0.43 0.03 0.85 827.26 1.01 575 255 42 27 TRUE 1.34
uterine cancer KRAS_G12D ARID1A 21 153 Metastasis 0.73 0.02 1.47 1667.02 1.00 267 10 142 11 TRUE 1.32
uterine cancer KRAS_G12D ARID1A 36 374 Primary 0.71 0.09 1.32 1248.30 1.00 414 13 351 23 TRUE 1.64
cancer of unknown primary KRAS_G12D ARID1A 43 109 Tumor Type:overall -0.09 -4.37 3.89 1493.33 1.00 576 36 102 7 TRUE 0.02
colorectal cancer KRAS_G12D ARID1A 301 315 Tumor Type:overall -0.39 -1.70 0.82 1729.43 1.00 1732 267 281 34 TRUE 0.27
non-small cell lung cancer KRAS_G12D ARID1A 151 284 Tumor Type:overall -0.62 -1.75 0.43 1382.40 1.00 3277 144 277 7 TRUE 0.55
pancreatic cancer KRAS_G12D ARID1A 485 127 Tumor Type:overall 0.48 -0.08 1.03 879.87 1.01 925 430 72 55 TRUE 1.04
uterine cancer KRAS_G12D ARID1A 57 527 Tumor Type:overall 0.72 -0.22 1.84 1514.65 1.00 681 23 493 34 TRUE 0.76
colorectal cancer KRAS_G12D PIK3R1 113 27 Metastasis -0.02 -0.94 0.84 1435.07 1.00 747 109 23 4 TRUE 0.01
colorectal cancer KRAS_G12D PIK3R1 181 89 Primary -0.08 -0.75 0.51 1342.82 1.00 1095 170 78 11 TRUE 0.10
non-small cell lung cancer KRAS_G12D PIK3R1 45 12 Metastasis -0.46 -4.17 1.39 1318.28 1.00 1326 45 12 0 TRUE 0.13
non-small cell lung cancer KRAS_G12D PIK3R1 106 43 Primary 0.16 -1.21 1.30 1530.44 1.00 2153 103 40 3 TRUE 0.09
uterine cancer KRAS_G12D PIK3R1 19 81 Metastasis -0.45 -1.42 0.43 1308.68 1.00 294 16 78 3 TRUE 0.47
uterine cancer KRAS_G12D PIK3R1 31 187 Primary -0.47 -1.28 0.28 1370.61 1.00 502 25 181 6 TRUE 0.62
colorectal cancer KRAS_G12D PIK3R1 294 116 Tumor Type:overall -0.05 -1.16 1.13 1443.76 1.00 1842 279 101 15 TRUE 0.03
non-small cell lung cancer KRAS_G12D PIK3R1 151 55 Tumor Type:overall -0.12 -2.55 1.62 1479.86 1.00 3479 148 52 3 TRUE 0.04
uterine cancer KRAS_G12D PIK3R1 50 268 Tumor Type:overall -0.46 -1.49 0.50 1486.70 1.00 796 41 259 9 TRUE 0.42
colorectal cancer KRAS_G12D IKZF1 112 24 Metastasis 0.15 -0.78 1.11 1193.17 1.00 749 107 19 5 TRUE 0.12
colorectal cancer KRAS_G12D IKZF1 180 62 Primary -0.23 -1.08 0.49 1361.21 1.00 1108 174 56 6 TRUE 0.26
non-small cell lung cancer KRAS_G12D IKZF1 45 36 Metastasis -0.35 -1.81 0.90 788.79 1.00 1302 44 35 1 TRUE 0.21
non-small cell lung cancer KRAS_G12D IKZF1 106 46 Primary -0.34 -1.76 0.76 863.99 1.01 2150 104 44 2 TRUE 0.22
colorectal cancer KRAS_G12D IKZF1 292 86 Tumor Type:overall -0.04 -1.20 1.23 1490.93 1.00 1857 281 75 11 TRUE 0.03
non-small cell lung cancer KRAS_G12D IKZF1 151 82 Tumor Type:overall -0.33 -1.80 0.99 657.30 1.01 3452 148 79 3 TRUE 0.19
cancer of unknown primary KRAS_G12D TERT 42 74 Metastasis -2.70 -5.24 -0.55 11.77 1.36 592 41 73 1 TRUE 1.21
cancer of unknown primary KRAS_G12D TERT 7 11 Primary -2.97 -5.93 -0.30 18.71 1.20 50 7 11 0 TRUE 1.13
colorectal cancer KRAS_G12D TERT 111 27 Metastasis 0.12 -0.95 0.92 1439.64 1.00 747 108 24 3 TRUE 0.10
colorectal cancer KRAS_G12D TERT 184 71 Primary 0.45 -0.09 1.00 838.57 1.00 1108 169 56 15 TRUE 0.95
non-small cell lung cancer KRAS_G12D TERT 45 61 Metastasis -0.50 -1.82 0.52 1366.20 1.00 1282 44 60 1 TRUE 0.40
non-small cell lung cancer KRAS_G12D TERT 106 105 Primary -0.40 -1.37 0.47 1448.75 1.00 2095 102 101 4 TRUE 0.39
uterine cancer KRAS_G12D TERT 18 19 Metastasis -1.75 -4.72 0.08 1085.36 1.00 341 18 19 0 TRUE 0.82
uterine cancer KRAS_G12D TERT 30 46 Primary -1.58 -4.17 0.06 1096.42 1.00 600 29 45 1 TRUE 0.87
cancer of unknown primary KRAS_G12D TERT 49 85 Tumor Type:overall -2.80 -5.31 -0.34 14.32 1.27 642 48 84 1 TRUE 1.16
colorectal cancer KRAS_G12D TERT 295 98 Tumor Type:overall 0.27 -0.84 1.17 1480.41 1.00 1855 277 80 18 TRUE 0.21
non-small cell lung cancer KRAS_G12D TERT 151 166 Tumor Type:overall -0.43 -1.65 0.66 1401.48 1.00 3377 146 161 5 TRUE 0.32
uterine cancer KRAS_G12D TERT 48 65 Tumor Type:overall -1.63 -4.32 0.19 1078.65 1.00 941 47 64 1 TRUE 0.83
cancer of unknown primary KRAS_G12D FAT1 43 64 Metastasis -0.92 -2.74 0.39 1470.36 1.00 602 41 62 2 FALSE 0.62
colorectal cancer KRAS_G12D FAT1 113 62 Metastasis -0.48 -1.25 0.23 1486.71 1.00 730 107 56 6 FALSE 0.71
colorectal cancer KRAS_G12D FAT1 183 165 Primary -0.61 -1.21 -0.08 1423.61 1.00 1061 170 152 13 FALSE 1.51
non-small cell lung cancer KRAS_G12D FAT1 45 123 Metastasis -0.64 -2.29 0.30 535.65 1.01 1222 44 122 1 FALSE 0.47
non-small cell lung cancer KRAS_G12D FAT1 107 182 Primary -0.06 -0.75 0.58 960.78 1.01 2044 97 172 10 FALSE 0.07
uterine cancer KRAS_G12D FAT1 20 51 Metastasis 0.25 -1.05 1.53 97.44 1.04 332 15 46 5 FALSE 0.14
uterine cancer KRAS_G12D FAT1 30 132 Primary -1.20 -3.41 0.06 1183.56 1.00 573 29 131 1 FALSE 0.78
cancer of unknown primary KRAS_G12D FAT1 43 64 Tumor Type:overall -0.70 -5.04 4.21 1566.14 1.00 602 41 62 2 FALSE 0.12
colorectal cancer KRAS_G12D FAT1 296 227 Tumor Type:overall -0.56 -1.50 0.38 1639.87 1.00 1791 277 208 19 FALSE 0.53
non-small cell lung cancer KRAS_G12D FAT1 152 305 Tumor Type:overall -0.35 -1.79 0.69 1092.39 1.00 3266 141 294 11 FALSE 0.23
uterine cancer KRAS_G12D FAT1 50 183 Tumor Type:overall -0.49 -2.59 1.18 1213.56 1.00 905 44 177 6 FALSE 0.22
colorectal cancer KRAS_G12D FGFR4 182 46 Primary 0.40 -0.43 1.14 1268.35 1.00 1127 173 37 9 TRUE 0.51
colorectal cancer KRAS_G12D FGFR4 182 46 Tumor Type:overall 0.25 -4.30 4.63 1484.46 1.00 1127 173 37 9 TRUE 0.04
colorectal cancer KRAS_G12D CIC 111 37 Metastasis -0.23 -1.03 0.53 1443.08 1.00 740 107 33 4 TRUE 0.24
colorectal cancer KRAS_G12D CIC 183 100 Primary -0.16 -0.80 0.38 1394.15 1.00 1093 171 88 12 TRUE 0.22
non-small cell lung cancer KRAS_G12D CIC 45 53 Metastasis -0.15 -1.98 1.11 1388.69 1.00 1294 44 52 1 TRUE 0.07
non-small cell lung cancer KRAS_G12D CIC 106 39 Primary 0.83 -0.23 1.74 1411.91 1.00 2161 101 34 5 TRUE 0.99
uterine cancer KRAS_G12D CIC 18 20 Metastasis 0.18 -1.26 1.47 1387.40 1.00 343 16 18 2 TRUE 0.10
uterine cancer KRAS_G12D CIC 30 55 Primary -0.03 -1.40 1.05 1244.56 1.00 607 28 53 2 TRUE 0.02
colorectal cancer KRAS_G12D CIC 294 137 Tumor Type:overall -0.20 -1.29 0.75 1518.17 1.00 1833 278 121 16 TRUE 0.16
non-small cell lung cancer KRAS_G12D CIC 151 92 Tumor Type:overall 0.34 -1.41 2.01 1448.08 1.00 3455 145 86 6 TRUE 0.16
uterine cancer KRAS_G12D CIC 48 75 Tumor Type:overall 0.05 -1.42 1.40 1317.41 1.00 950 44 71 4 TRUE 0.02
colorectal cancer KRAS_G12D KDM6A 111 13 Metastasis 0.51 -0.54 1.53 1257.43 1.00 758 108 10 3 FALSE 0.48
colorectal cancer KRAS_G12D KDM6A 181 49 Primary 0.53 -0.17 1.17 1471.24 1.00 1124 171 39 10 FALSE 0.90
non-small cell lung cancer KRAS_G12D KDM6A 45 23 Metastasis -0.41 -3.21 1.06 1138.34 1.00 1315 45 23 0 FALSE 0.14
non-small cell lung cancer KRAS_G12D KDM6A 106 38 Primary 0.08 -1.40 1.27 1236.91 1.00 2160 103 35 3 FALSE 0.05
pancreatic cancer KRAS_G12D KDM6A 201 24 Metastasis 0.36 -0.27 1.02 1112.19 1.00 367 189 12 12 FALSE 0.56
pancreatic cancer KRAS_G12D KDM6A 280 35 Primary 0.19 -0.44 0.76 1391.52 1.00 590 269 24 11 FALSE 0.27
uterine cancer KRAS_G12D KDM6A 18 16 Metastasis -0.43 -2.28 1.03 441.33 1.01 344 17 15 1 FALSE 0.20
uterine cancer KRAS_G12D KDM6A 30 38 Primary -0.51 -2.26 0.88 354.11 1.02 614 29 37 1 FALSE 0.27
colorectal cancer KRAS_G12D KDM6A 292 62 Tumor Type:overall 0.51 -0.84 1.68 1526.46 1.00 1882 279 49 13 FALSE 0.40
non-small cell lung cancer KRAS_G12D KDM6A 151 61 Tumor Type:overall -0.15 -2.30 1.31 1192.76 1.00 3475 148 58 3 FALSE 0.06
pancreatic cancer KRAS_G12D KDM6A 481 59 Tumor Type:overall 0.28 -0.49 1.01 1218.65 1.00 957 458 36 23 FALSE 0.34
uterine cancer KRAS_G12D KDM6A 48 54 Tumor Type:overall -0.44 -2.30 1.23 339.26 1.02 958 46 52 2 FALSE 0.20
colorectal cancer KRAS_G12D NCOR1 111 37 Metastasis -0.54 -1.46 0.26 858.90 1.00 737 108 34 3 FALSE 0.65
colorectal cancer KRAS_G12D NCOR1 181 98 Primary -0.49 -1.21 0.15 723.02 1.00 1093 172 89 9 FALSE 0.82
non-small cell lung cancer KRAS_G12D NCOR1 46 52 Metastasis -0.36 -1.78 0.83 1142.60 1.00 1294 44 50 2 FALSE 0.22
non-small cell lung cancer KRAS_G12D NCOR1 106 52 Primary -0.64 -2.24 0.57 1086.21 1.00 2143 105 51 1 FALSE 0.42
uterine cancer KRAS_G12D NCOR1 19 23 Metastasis 0.39 -1.12 1.84 1324.52 1.00 346 16 20 3 FALSE 0.23
uterine cancer KRAS_G12D NCOR1 30 67 Primary -0.54 -2.22 0.68 1464.26 1.00 603 29 66 1 FALSE 0.32
colorectal cancer KRAS_G12D NCOR1 292 135 Tumor Type:overall -0.52 -1.54 0.42 1221.18 1.00 1830 280 123 12 FALSE 0.48
non-small cell lung cancer KRAS_G12D NCOR1 152 104 Tumor Type:overall -0.50 -2.20 0.95 1329.26 1.00 3437 149 101 3 FALSE 0.28
uterine cancer KRAS_G12D NCOR1 49 90 Tumor Type:overall -0.08 -1.96 1.57 1505.75 1.00 949 45 86 4 FALSE 0.03
colorectal cancer KRAS_G12D POLE 111 28 Metastasis 0.08 -0.95 1.10 1444.91 1.00 745 106 23 5 TRUE 0.05
colorectal cancer KRAS_G12D POLE 181 113 Primary -0.56 -1.25 0.10 1522.30 1.00 1083 172 104 9 TRUE 0.98
non-small cell lung cancer KRAS_G12D POLE 45 59 Metastasis -1.03 -3.81 0.40 1276.78 1.00 1280 45 59 0 TRUE 0.39
non-small cell lung cancer KRAS_G12D POLE 106 77 Primary -0.31 -1.48 0.66 1049.60 1.00 2126 102 73 4 TRUE 0.24
uterine cancer KRAS_G12D POLE 19 27 Metastasis 1.18 0.00 2.36 1132.72 1.00 344 14 22 5 TRUE 1.28
uterine cancer KRAS_G12D POLE 30 84 Primary 0.10 -1.19 1.09 1312.34 1.00 597 27 81 3 TRUE 0.07
colorectal cancer KRAS_G12D POLE 292 141 Tumor Type:overall -0.22 -1.72 1.28 1438.54 1.00 1828 278 127 14 TRUE 0.11
non-small cell lung cancer KRAS_G12D POLE 151 136 Tumor Type:overall -0.67 -2.94 0.71 1252.70 1.00 3406 147 132 4 TRUE 0.31
uterine cancer KRAS_G12D POLE 49 111 Tumor Type:overall 0.60 -1.17 2.30 1365.24 1.00 941 41 103 8 TRUE 0.30
non-small cell lung cancer KRAS_G12D CUL3 45 26 Metastasis -1.77 -5.22 0.21 810.56 1.00 1312 45 26 0 FALSE 0.71
non-small cell lung cancer KRAS_G12D CUL3 106 51 Primary -1.57 -4.36 0.22 716.74 1.00 2149 105 50 1 FALSE 0.74
non-small cell lung cancer KRAS_G12D CUL3 151 77 Tumor Type:overall -1.64 -4.74 0.31 848.82 1.00 3461 150 76 1 FALSE 0.71
colorectal cancer KRAS_G12D ABL1 128 17 Metastasis -0.83 -2.37 0.33 1326.42 1.00 811 127 16 1 TRUE 0.63
colorectal cancer KRAS_G12D ABL1 204 56 Primary -0.62 -1.58 0.20 1446.97 1.00 1249 199 51 5 TRUE 0.76
colorectal cancer KRAS_G12D ABL1 332 73 Tumor Type:overall -0.71 -2.20 0.59 1428.78 1.00 2060 326 67 6 TRUE 0.49
colorectal cancer KRAS_G12D FOXP1 111 15 Metastasis -0.41 -1.67 0.87 1460.39 1.00 754 109 13 2 FALSE 0.28
colorectal cancer KRAS_G12D FOXP1 180 55 Primary -0.67 -1.72 0.17 1427.91 1.00 1115 176 51 4 FALSE 0.78
colorectal cancer KRAS_G12D FOXP1 291 70 Tumor Type:overall -0.54 -1.94 0.94 1561.43 1.00 1869 285 64 6 FALSE 0.34
colorectal cancer KRAS_G12D NOTCH2 111 18 Metastasis -0.31 -1.40 0.76 1583.55 1.00 753 109 16 2 TRUE 0.24
colorectal cancer KRAS_G12D NOTCH2 180 55 Primary -0.28 -1.15 0.50 1471.39 1.00 1119 174 49 6 TRUE 0.30
non-small cell lung cancer KRAS_G12D NOTCH2 45 40 Metastasis -0.01 -1.27 1.10 1523.27 1.00 1303 43 38 2 TRUE 0.01
non-small cell lung cancer KRAS_G12D NOTCH2 106 75 Primary -0.11 -1.25 0.80 1379.53 1.00 2127 103 72 3 TRUE 0.08
colorectal cancer KRAS_G12D NOTCH2 291 73 Tumor Type:overall -0.30 -1.56 0.85 1370.79 1.00 1872 283 65 8 TRUE 0.19
non-small cell lung cancer KRAS_G12D NOTCH2 151 115 Tumor Type:overall -0.07 -1.43 1.12 1389.20 1.00 3430 146 110 5 TRUE 0.04
non-small cell lung cancer KRAS_G12D DDR2 45 45 Metastasis -1.93 -5.49 -0.07 234.76 1.02 1292 45 45 0 TRUE 0.76
non-small cell lung cancer KRAS_G12D DDR2 106 53 Primary -1.70 -4.43 0.00 268.17 1.02 2140 105 52 1 TRUE 0.84
uterine cancer KRAS_G12D DDR2 18 11 Metastasis 0.35 -1.42 1.74 1257.03 1.00 353 17 10 1 TRUE 0.18
uterine cancer KRAS_G12D DDR2 30 46 Primary 0.37 -0.92 1.47 1119.22 1.00 612 27 43 3 TRUE 0.27
non-small cell lung cancer KRAS_G12D DDR2 151 98 Tumor Type:overall -1.77 -4.83 0.04 252.21 1.02 3432 150 97 1 TRUE 0.79
uterine cancer KRAS_G12D DDR2 48 57 Tumor Type:overall 0.36 -1.42 1.86 1307.07 1.00 965 44 53 4 TRUE 0.18
colorectal cancer KRAS_G12D TGFBR2 111 26 Metastasis 0.07 -0.85 0.90 1384.31 1.00 745 107 22 4 TRUE 0.06
colorectal cancer KRAS_G12D TGFBR2 181 88 Primary 0.03 -0.61 0.58 1669.29 1.00 1090 169 76 12 TRUE 0.03
non-small cell lung cancer KRAS_G12D TGFBR2 45 27 Metastasis 0.04 -1.57 1.36 1460.75 1.00 1313 44 26 1 TRUE 0.02
non-small cell lung cancer KRAS_G12D TGFBR2 106 29 Primary 0.16 -1.38 1.38 1203.47 1.00 2167 104 27 2 TRUE 0.08
colorectal cancer KRAS_G12D TGFBR2 292 114 Tumor Type:overall 0.07 -1.10 1.38 1431.20 1.00 1835 276 98 16 TRUE 0.04
non-small cell lung cancer KRAS_G12D TGFBR2 151 56 Tumor Type:overall 0.09 -1.63 1.47 1485.84 1.00 3480 148 53 3 TRUE 0.04
colorectal cancer KRAS_G12D SMO 128 19 Metastasis -0.24 -1.40 0.68 1529.29 1.00 808 126 17 2 TRUE 0.20
colorectal cancer KRAS_G12D SMO 205 52 Primary -0.11 -0.90 0.60 1514.43 1.00 1254 198 45 7 TRUE 0.11
non-small cell lung cancer KRAS_G12D SMO 47 29 Metastasis 0.62 -0.60 1.63 225.33 1.01 1358 45 27 2 TRUE 0.55
non-small cell lung cancer KRAS_G12D SMO 109 46 Primary 0.60 -0.57 1.45 147.75 1.01 2224 105 42 4 TRUE 0.62
uterine cancer KRAS_G12D SMO 18 19 Metastasis 0.61 -0.69 1.72 256.79 1.01 366 16 17 2 TRUE 0.47
uterine cancer KRAS_G12D SMO 32 33 Primary 0.54 -0.73 1.61 235.21 1.01 708 30 31 2 TRUE 0.42
colorectal cancer KRAS_G12D SMO 333 71 Tumor Type:overall -0.18 -1.41 0.88 1418.21 1.00 2062 324 62 9 TRUE 0.12
non-small cell lung cancer KRAS_G12D SMO 156 75 Tumor Type:overall 0.58 -0.63 1.65 258.36 1.00 3582 150 69 6 TRUE 0.46
uterine cancer KRAS_G12D SMO 50 52 Tumor Type:overall 0.58 -0.79 1.70 285.10 1.01 1074 46 48 4 TRUE 0.41
colorectal cancer KRAS_G12D RPS6KA4 180 53 Primary -0.77 -1.97 0.19 1423.79 1.00 1115 176 49 4 FALSE 0.79
colorectal cancer KRAS_G12D RPS6KA4 180 53 Tumor Type:overall -0.62 -4.86 4.41 1503.09 1.00 1115 176 49 4 FALSE 0.11
colorectal cancer KRAS_G12D KMT2A 112 37 Metastasis -0.06 -0.87 0.68 1537.27 1.00 741 107 32 5 FALSE 0.05
colorectal cancer KRAS_G12D KMT2A 180 111 Primary -0.04 -0.62 0.51 1424.21 1.00 1091 166 97 14 FALSE 0.05
non-small cell lung cancer KRAS_G12D KMT2A 45 53 Metastasis -1.52 -4.54 0.21 1124.21 1.00 1288 45 53 0 FALSE 0.68
non-small cell lung cancer KRAS_G12D KMT2A 106 61 Primary -0.98 -2.87 0.30 1322.81 1.00 2136 104 59 2 FALSE 0.64
uterine cancer KRAS_G12D KMT2A 19 30 Metastasis -0.74 -2.93 1.06 848.95 1.00 337 17 28 2 FALSE 0.35
uterine cancer KRAS_G12D KMT2A 30 79 Primary -1.86 -5.39 0.00 1090.67 1.00 601 30 79 0 FALSE 0.71
colorectal cancer KRAS_G12D KMT2A 292 148 Tumor Type:overall -0.06 -1.16 0.91 1470.61 1.00 1832 273 129 19 FALSE 0.04
non-small cell lung cancer KRAS_G12D KMT2A 151 114 Tumor Type:overall -1.20 -3.47 0.54 1209.38 1.00 3424 149 112 2 FALSE 0.61
uterine cancer KRAS_G12D KMT2A 49 109 Tumor Type:overall -1.23 -3.76 0.81 1351.37 1.00 938 47 107 2 FALSE 0.50
colorectal cancer KRAS_G12D JAK3 128 22 Metastasis -1.80 -3.50 -0.37 439.57 1.00 806 127 21 1 TRUE 1.53
colorectal cancer KRAS_G12D JAK3 204 41 Primary -1.85 -3.59 -0.51 451.69 1.00 1256 203 40 1 TRUE 1.64
non-small cell lung cancer KRAS_G12D JAK3 47 23 Metastasis -0.21 -3.45 1.34 1050.50 1.00 1362 47 23 0 TRUE 0.06
non-small cell lung cancer KRAS_G12D JAK3 109 60 Primary 0.62 -0.40 1.46 1252.28 1.00 2212 103 54 6 TRUE 0.71
colorectal cancer KRAS_G12D JAK3 332 63 Tumor Type:overall -1.83 -3.54 -0.43 542.84 1.00 2062 330 61 2 TRUE 1.55
non-small cell lung cancer KRAS_G12D JAK3 156 83 Tumor Type:overall 0.22 -2.08 1.73 1354.88 1.00 3574 150 77 6 TRUE 0.09
non-small cell lung cancer KRAS_G12D PAK7 45 61 Metastasis -0.01 -1.16 0.99 1213.80 1.00 1283 42 58 3 FALSE 0.00
non-small cell lung cancer KRAS_G12D PAK7 106 72 Primary -0.30 -1.50 0.63 1156.77 1.00 2128 104 70 2 FALSE 0.23
non-small cell lung cancer KRAS_G12D PAK7 151 133 Tumor Type:overall -0.15 -1.50 1.03 1225.08 1.00 3411 146 128 5 FALSE 0.09
non-small cell lung cancer KRAS_G12D STAG2 45 43 Metastasis -0.30 -1.76 0.81 1173.05 1.00 1299 44 42 1 TRUE 0.19
non-small cell lung cancer KRAS_G12D STAG2 106 59 Primary -0.16 -1.32 0.85 918.44 1.00 2138 103 56 3 TRUE 0.11
uterine cancer KRAS_G12D STAG2 21 29 Metastasis 0.55 -0.82 2.04 5.58 1.33 347 16 24 5 TRUE 0.29
uterine cancer KRAS_G12D STAG2 30 56 Primary -0.23 -1.89 1.04 179.74 1.02 604 29 55 1 TRUE 0.12
non-small cell lung cancer KRAS_G12D STAG2 151 102 Tumor Type:overall -0.23 -1.64 1.00 1253.15 1.00 3437 147 98 4 TRUE 0.13
uterine cancer KRAS_G12D STAG2 51 85 Tumor Type:overall 0.14 -1.30 1.61 12.66 1.11 951 45 79 6 TRUE 0.06
colorectal cancer KRAS_G12D BRCA2 111 48 Metastasis -0.68 -1.61 0.20 1472.41 1.00 733 107 44 4 TRUE 0.90
colorectal cancer KRAS_G12D BRCA2 181 142 Primary -0.83 -1.49 -0.22 1450.97 1.00 1080 172 133 9 TRUE 1.92
non-small cell lung cancer KRAS_G12D BRCA2 45 67 Metastasis -0.87 -2.54 0.44 1409.91 1.00 1279 44 66 1 TRUE 0.59
non-small cell lung cancer KRAS_G12D BRCA2 106 68 Primary -0.78 -2.29 0.35 1516.44 1.00 2130 104 66 2 TRUE 0.60
uterine cancer KRAS_G12D BRCA2 19 34 Metastasis -0.56 -2.22 0.83 1368.48 1.00 338 17 32 2 TRUE 0.33
uterine cancer KRAS_G12D BRCA2 30 100 Primary -1.14 -2.85 0.07 1390.40 1.00 589 29 99 1 TRUE 0.88
colorectal cancer KRAS_G12D BRCA2 292 190 Tumor Type:overall -0.74 -1.88 0.48 1525.94 1.00 1813 279 177 13 TRUE 0.73
non-small cell lung cancer KRAS_G12D BRCA2 151 135 Tumor Type:overall -0.81 -2.49 0.60 1436.28 1.00 3409 148 132 3 TRUE 0.49
uterine cancer KRAS_G12D BRCA2 49 134 Tumor Type:overall -0.83 -2.74 0.98 1477.96 1.00 927 46 131 3 TRUE 0.45
colorectal cancer KRAS_G12D NOTCH3 111 58 Metastasis -0.77 -1.57 -0.03 1384.73 1.00 723 107 54 4 TRUE 1.32
colorectal cancer KRAS_G12D NOTCH3 180 142 Primary -0.77 -1.39 -0.19 1416.07 1.00 1061 170 132 10 TRUE 1.94
non-small cell lung cancer KRAS_G12D NOTCH3 45 51 Metastasis -1.14 -4.02 0.32 844.90 1.00 1288 45 51 0 TRUE 0.49
non-small cell lung cancer KRAS_G12D NOTCH3 106 77 Primary -0.65 -1.96 0.44 843.35 1.00 2125 103 74 3 TRUE 0.53
uterine cancer KRAS_G12D NOTCH3 18 29 Metastasis -2.03 -5.10 -0.11 648.43 1.00 335 18 29 0 TRUE 0.95
uterine cancer KRAS_G12D NOTCH3 30 62 Primary -1.87 -4.57 -0.13 599.14 1.00 599 29 61 1 TRUE 0.98
colorectal cancer KRAS_G12D NOTCH3 291 200 Tumor Type:overall -0.75 -1.73 0.28 1496.15 1.00 1784 277 186 14 TRUE 0.84
non-small cell lung cancer KRAS_G12D NOTCH3 151 128 Tumor Type:overall -0.87 -2.93 0.57 854.50 1.00 3413 148 125 3 TRUE 0.48
uterine cancer KRAS_G12D NOTCH3 48 91 Tumor Type:overall -1.92 -4.68 -0.02 673.70 1.00 934 47 90 1 TRUE 0.93
colorectal cancer KRAS_G12D NOTCH4 111 33 Metastasis -0.49 -1.63 0.33 1210.37 1.00 737 109 31 2 TRUE 0.45
colorectal cancer KRAS_G12D NOTCH4 182 89 Primary -0.13 -0.78 0.43 1390.01 1.00 1096 170 77 12 TRUE 0.17
non-small cell lung cancer KRAS_G12D NOTCH4 45 55 Metastasis -0.41 -1.71 0.66 892.01 1.00 1286 43 53 2 TRUE 0.30
non-small cell lung cancer KRAS_G12D NOTCH4 106 84 Primary -0.58 -1.82 0.40 972.11 1.00 2114 104 82 2 TRUE 0.50
colorectal cancer KRAS_G12D NOTCH4 293 122 Tumor Type:overall -0.30 -1.56 0.82 1281.35 1.00 1833 279 108 14 TRUE 0.21
non-small cell lung cancer KRAS_G12D NOTCH4 151 139 Tumor Type:overall -0.50 -1.89 0.71 1066.80 1.00 3400 147 135 4 TRUE 0.35
colorectal cancer KRAS_G12D FGFR3 128 14 Metastasis -1.41 -4.66 0.16 1126.71 1.00 812 128 14 0 TRUE 0.52
colorectal cancer KRAS_G12D FGFR3 204 46 Primary -0.56 -1.66 0.35 920.38 1.00 1256 199 41 5 TRUE 0.54
colorectal cancer KRAS_G12D FGFR3 332 60 Tumor Type:overall -0.99 -3.29 0.47 1085.98 1.01 2068 327 55 5 TRUE 0.52
non-small cell lung cancer KRAS_G12D MAP3K13 45 23 Metastasis -1.52 -4.88 0.58 1297.18 1.00 1315 45 23 0 FALSE 0.57
non-small cell lung cancer KRAS_G12D MAP3K13 106 29 Primary -1.24 -4.06 0.62 1268.42 1.00 2164 105 28 1 FALSE 0.53
non-small cell lung cancer KRAS_G12D MAP3K13 151 52 Tumor Type:overall -1.37 -4.30 0.67 1330.55 1.00 3479 150 51 1 FALSE 0.55
colorectal cancer KRAS_G12D IGF1R 111 22 Metastasis -0.69 -2.31 0.34 1198.31 1.00 750 110 21 1 TRUE 0.54
colorectal cancer KRAS_G12D IGF1R 180 58 Primary -0.31 -1.17 0.46 1034.97 1.00 1116 173 51 7 TRUE 0.34
non-small cell lung cancer KRAS_G12D IGF1R 45 26 Metastasis -1.53 -5.08 0.67 1015.92 1.00 1312 45 26 0 TRUE 0.52
non-small cell lung cancer KRAS_G12D IGF1R 106 28 Primary -1.21 -4.14 0.80 935.48 1.00 2165 105 27 1 TRUE 0.47
colorectal cancer KRAS_G12D IGF1R 291 80 Tumor Type:overall -0.47 -1.80 0.71 1283.49 1.00 1866 283 72 8 TRUE 0.36
non-small cell lung cancer KRAS_G12D IGF1R 151 54 Tumor Type:overall -1.36 -4.60 0.75 992.27 1.00 3477 150 53 1 TRUE 0.48
cancer of unknown primary KRAS_G12D KEAP1 42 66 Metastasis -5.95 -14.72 -1.16 1146.66 1.00 591 42 66 0 FALSE 0.87
non-small cell lung cancer KRAS_G12D KEAP1 45 234 Metastasis 0.35 -0.34 1.06 1513.91 1.00 1124 33 222 12 FALSE 0.49
non-small cell lung cancer KRAS_G12D KEAP1 106 304 Primary -0.34 -1.06 0.22 1496.15 1.00 1911 97 295 9 FALSE 0.52
cancer of unknown primary KRAS_G12D KEAP1 42 66 Tumor Type:overall -4.45 -12.13 2.68 1379.89 1.00 591 42 66 0 FALSE 0.66
non-small cell lung cancer KRAS_G12D KEAP1 151 538 Tumor Type:overall 0.00 -1.26 1.30 1475.11 1.00 3035 130 517 21 FALSE 0.00
colorectal cancer KRAS_G12D KDM5C 111 14 Metastasis 0.66 -0.38 1.76 1308.35 1.00 758 107 10 4 FALSE 0.65
colorectal cancer KRAS_G12D KDM5C 182 55 Primary 0.31 -0.43 0.94 1493.06 1.00 1124 173 46 9 FALSE 0.43
non-small cell lung cancer KRAS_G12D KDM5C 45 41 Metastasis 0.08 -1.35 1.12 180.52 1.01 1299 43 39 2 FALSE 0.05
non-small cell lung cancer KRAS_G12D KDM5C 107 65 Primary 0.00 -1.38 0.92 134.78 1.01 2133 104 62 3 FALSE 0.00
uterine cancer KRAS_G12D KDM5C 18 21 Metastasis 0.02 -1.47 1.34 981.24 1.00 343 16 19 2 FALSE 0.01
uterine cancer KRAS_G12D KDM5C 30 46 Primary -0.25 -1.85 0.95 908.94 1.00 615 29 45 1 FALSE 0.14
colorectal cancer KRAS_G12D KDM5C 293 69 Tumor Type:overall 0.48 -0.87 2.06 1314.12 1.00 1882 280 56 13 FALSE 0.30
non-small cell lung cancer KRAS_G12D KDM5C 152 106 Tumor Type:overall 0.05 -1.39 1.15 192.57 1.01 3432 147 101 5 FALSE 0.03
uterine cancer KRAS_G12D KDM5C 48 67 Tumor Type:overall -0.11 -1.75 1.15 1190.17 1.00 958 45 64 3 FALSE 0.06
cancer of unknown primary KRAS_G12D CDKN2A 42 66 Metastasis 0.21 -0.82 1.13 1070.17 1.00 606 37 61 5 TRUE 0.17
non-small cell lung cancer KRAS_G12D CDKN2A 47 92 Metastasis -0.40 -1.40 0.46 1424.35 1.00 1301 45 90 2 TRUE 0.39
non-small cell lung cancer KRAS_G12D CDKN2A 109 184 Primary -0.30 -1.07 0.39 1316.22 1.00 2098 102 177 7 TRUE 0.38
pancreatic cancer KRAS_G12D CDKN2A 212 121 Metastasis 0.63 0.32 1.01 1185.54 1.00 336 152 61 60 TRUE 3.50
pancreatic cancer KRAS_G12D CDKN2A 291 173 Primary 0.43 0.11 0.69 1259.24 1.00 536 227 109 64 TRUE 2.26
cancer of unknown primary KRAS_G12D CDKN2A 42 66 Tumor Type:overall 0.20 -4.26 4.42 1428.95 1.00 606 37 61 5 TRUE 0.04
non-small cell lung cancer KRAS_G12D CDKN2A 156 276 Tumor Type:overall -0.34 -1.32 0.60 1248.78 1.00 3399 147 267 9 TRUE 0.32
pancreatic cancer KRAS_G12D CDKN2A 503 294 Tumor Type:overall 0.52 0.05 1.02 1431.27 1.00 872 379 170 124 TRUE 1.39
colorectal cancer KRAS_G12D EPHB1 111 25 Metastasis -0.87 -2.33 0.16 1070.33 1.00 743 110 24 1 FALSE 0.79
colorectal cancer KRAS_G12D EPHB1 180 57 Primary -0.68 -1.60 0.17 983.56 1.00 1112 175 52 5 FALSE 0.91
non-small cell lung cancer KRAS_G12D EPHB1 45 59 Metastasis -0.99 -2.25 0.47 14.02 1.08 1283 43 57 2 FALSE 0.81
non-small cell lung cancer KRAS_G12D EPHB1 106 99 Primary -1.22 -2.51 0.05 337.13 1.02 2105 105 98 1 FALSE 1.29
colorectal cancer KRAS_G12D EPHB1 291 82 Tumor Type:overall -0.78 -2.08 0.26 1292.27 1.00 1855 285 76 6 FALSE 0.75
non-small cell lung cancer KRAS_G12D EPHB1 151 158 Tumor Type:overall -1.10 -2.35 0.34 32.98 1.05 3388 148 155 3 FALSE 0.97
colorectal cancer KRAS_G12D IRS2 111 11 Metastasis -0.48 -2.46 0.95 1497.36 1.00 758 110 10 1 FALSE 0.24
colorectal cancer KRAS_G12D IRS2 180 76 Primary -0.07 -0.74 0.57 1554.14 1.00 1103 170 66 10 FALSE 0.07
non-small cell lung cancer KRAS_G12D IRS2 45 36 Metastasis -4.97 -12.11 -0.73 219.38 1.02 1303 45 36 0 FALSE 1.03
non-small cell lung cancer KRAS_G12D IRS2 106 48 Primary -4.99 -12.06 -0.77 217.54 1.02 2145 106 48 0 FALSE 1.02
uterine cancer KRAS_G12D IRS2 18 22 Metastasis -1.46 -4.07 0.56 1044.14 1.00 342 17 21 1 FALSE 0.67
uterine cancer KRAS_G12D IRS2 30 52 Primary -1.94 -5.22 0.04 832.87 1.01 602 30 52 0 FALSE 0.74
colorectal cancer KRAS_G12D IRS2 291 87 Tumor Type:overall -0.28 -2.46 1.57 1425.68 1.00 1861 280 76 11 FALSE 0.11
non-small cell lung cancer KRAS_G12D IRS2 151 84 Tumor Type:overall -4.93 -11.77 -0.67 212.66 1.02 3448 151 84 0 FALSE 1.02
uterine cancer KRAS_G12D IRS2 48 74 Tumor Type:overall -1.67 -4.56 0.39 947.71 1.00 944 47 73 1 FALSE 0.73
colorectal cancer KRAS_G12D FANCA 111 12 Metastasis -0.44 -2.28 0.82 1561.52 1.00 758 110 11 1 TRUE 0.25
colorectal cancer KRAS_G12D FANCA 180 53 Primary -0.12 -1.03 0.61 1195.60 1.00 1119 173 46 7 TRUE 0.11
non-small cell lung cancer KRAS_G12D FANCA 45 34 Metastasis 0.51 -0.88 1.69 1621.46 1.00 1307 42 31 3 TRUE 0.37
non-small cell lung cancer KRAS_G12D FANCA 106 35 Primary -0.04 -1.66 1.07 1436.92 1.00 2160 105 34 1 TRUE 0.02
colorectal cancer KRAS_G12D FANCA 291 65 Tumor Type:overall -0.30 -2.09 1.26 1381.56 1.00 1877 283 57 8 TRUE 0.14
non-small cell lung cancer KRAS_G12D FANCA 151 69 Tumor Type:overall 0.21 -1.49 1.61 1531.24 1.00 3467 147 65 4 TRUE 0.10
non-small cell lung cancer KRAS_G12D IL7R 45 35 Metastasis -0.84 -2.58 0.64 1480.00 1.00 1303 44 34 1 FALSE 0.52
non-small cell lung cancer KRAS_G12D IL7R 106 56 Primary -0.95 -2.71 0.45 1594.12 1.00 2146 105 55 1 FALSE 0.62
non-small cell lung cancer KRAS_G12D IL7R 151 91 Tumor Type:overall -0.90 -2.75 0.67 1623.31 1.00 3449 149 89 2 FALSE 0.54
uterine cancer KRAS_G12D PPP2R1A 18 52 Metastasis -1.18 -2.77 0.08 1266.21 1.00 316 17 51 1 FALSE 0.98
uterine cancer KRAS_G12D PPP2R1A 30 107 Primary -1.18 -2.67 -0.02 1156.95 1.00 544 28 105 2 FALSE 1.10
uterine cancer KRAS_G12D PPP2R1A 48 159 Tumor Type:overall -1.16 -2.78 0.12 1231.80 1.00 860 45 156 3 FALSE 0.94
colorectal cancer KRAS_G12D PIK3CB 111 12 Metastasis -2.42 -6.09 -0.30 1613.35 1.00 758 111 12 0 FALSE 1.03
colorectal cancer KRAS_G12D PIK3CB 180 56 Primary -1.83 -3.68 -0.46 1413.81 1.00 1119 178 54 2 FALSE 1.60
colorectal cancer KRAS_G12D PIK3CB 291 68 Tumor Type:overall -2.08 -4.95 0.03 1593.94 1.00 1877 289 66 2 FALSE 1.06
colorectal cancer KRAS_G12D ERBB3 111 39 Metastasis -0.18 -0.94 0.54 1037.06 1.00 735 107 35 4 TRUE 0.21
colorectal cancer KRAS_G12D ERBB3 181 83 Primary -0.11 -0.71 0.45 640.88 1.01 1099 170 72 11 TRUE 0.16
uterine cancer KRAS_G12D ERBB3 18 20 Metastasis -0.28 -1.99 0.98 840.67 1.00 340 17 19 1 TRUE 0.15
uterine cancer KRAS_G12D ERBB3 30 60 Primary -0.33 -1.80 0.86 801.92 1.00 594 28 58 2 TRUE 0.21
colorectal cancer KRAS_G12D ERBB3 292 122 Tumor Type:overall -0.14 -0.96 0.64 1134.44 1.00 1834 277 107 15 TRUE 0.14
uterine cancer KRAS_G12D ERBB3 48 80 Tumor Type:overall -0.30 -2.03 1.05 1031.93 1.00 934 45 77 3 TRUE 0.16
colorectal cancer KRAS_G12D SMAD4 129 149 Metastasis -0.04 -0.44 0.31 1304.69 1.00 703 110 130 19 TRUE 0.08
colorectal cancer KRAS_G12D SMAD4 207 211 Primary -0.03 -0.36 0.31 1447.49 1.00 1132 178 182 29 TRUE 0.05
non-small cell lung cancer KRAS_G12D SMAD4 47 49 Metastasis -1.06 -3.45 0.36 1357.53 1.00 1337 47 49 0 TRUE 0.49
non-small cell lung cancer KRAS_G12D SMAD4 109 67 Primary -0.57 -2.00 0.62 1191.41 1.00 2202 106 64 3 TRUE 0.42
pancreatic cancer KRAS_G12D SMAD4 209 108 Metastasis 0.00 -0.34 0.34 1123.46 1.00 324 172 71 37 TRUE 0.00
pancreatic cancer KRAS_G12D SMAD4 287 167 Primary 0.00 -0.33 0.32 1284.70 1.00 528 235 115 52 TRUE 0.00
colorectal cancer KRAS_G12D SMAD4 336 360 Tumor Type:overall -0.03 -0.50 0.38 1350.55 1.00 1835 288 312 48 TRUE 0.05
non-small cell lung cancer KRAS_G12D SMAD4 156 116 Tumor Type:overall -0.80 -2.56 0.54 1278.37 1.00 3539 153 113 3 TRUE 0.45
pancreatic cancer KRAS_G12D SMAD4 496 275 Tumor Type:overall 0.00 -0.45 0.46 1296.40 1.00 852 407 186 89 TRUE 0.00
colorectal cancer KRAS_G12D ATM 132 71 Metastasis 0.49 -0.21 1.11 1364.45 1.00 780 116 55 16 TRUE 0.81
colorectal cancer KRAS_G12D ATM 204 160 Primary -1.01 -1.76 -0.33 1387.03 1.00 1182 196 152 8 TRUE 2.22
non-small cell lung cancer KRAS_G12D ATM 47 122 Metastasis 0.21 -0.54 0.88 1584.37 1.00 1281 42 117 5 TRUE 0.25
non-small cell lung cancer KRAS_G12D ATM 111 166 Primary 0.25 -0.40 0.82 1417.15 1.00 2125 101 156 10 TRUE 0.39
uterine cancer KRAS_G12D ATM 20 39 Metastasis 0.38 -0.82 1.52 1163.65 1.00 356 16 35 4 TRUE 0.28
uterine cancer KRAS_G12D ATM 32 127 Primary -0.34 -1.56 0.59 1357.08 1.00 667 29 124 3 TRUE 0.27
colorectal cancer KRAS_G12D ATM 336 231 Tumor Type:overall -0.27 -2.03 1.39 1444.22 1.00 1962 312 207 24 TRUE 0.13
non-small cell lung cancer KRAS_G12D ATM 158 288 Tumor Type:overall 0.22 -0.66 1.02 1492.77 1.00 3406 143 273 15 TRUE 0.21
uterine cancer KRAS_G12D ATM 52 166 Tumor Type:overall 0.03 -1.46 1.50 1202.83 1.00 1023 45 159 7 TRUE 0.01
cancer of unknown primary KRAS_G12D RB1 43 65 Metastasis -0.44 -1.92 0.66 1488.45 1.00 607 40 62 3 TRUE 0.30
colorectal cancer KRAS_G12D RB1 205 58 Primary -0.60 -1.66 0.23 1383.82 1.00 1253 200 53 5 TRUE 0.67
non-small cell lung cancer KRAS_G12D RB1 47 96 Metastasis -0.88 -2.32 0.17 684.20 1.00 1293 46 95 1 TRUE 0.77
non-small cell lung cancer KRAS_G12D RB1 109 127 Primary -0.69 -1.80 0.25 807.03 1.00 2143 105 123 4 TRUE 0.72
uterine cancer KRAS_G12D RB1 18 29 Metastasis -1.77 -4.40 0.24 507.69 1.00 359 17 28 1 TRUE 0.86
uterine cancer KRAS_G12D RB1 32 65 Primary -2.10 -5.21 -0.20 743.67 1.00 690 32 65 0 TRUE 1.02
cancer of unknown primary KRAS_G12D RB1 43 65 Tumor Type:overall -0.39 -4.71 4.20 1487.58 1.00 607 40 62 3 TRUE 0.07
colorectal cancer KRAS_G12D RB1 205 58 Tumor Type:overall -0.47 -4.66 3.81 1585.74 1.00 1253 200 53 5 TRUE 0.09
non-small cell lung cancer KRAS_G12D RB1 156 223 Tumor Type:overall -0.78 -2.15 0.38 782.74 1.00 3436 151 218 5 TRUE 0.64
uterine cancer KRAS_G12D RB1 50 94 Tumor Type:overall -1.91 -4.56 0.06 596.85 1.00 1049 49 93 1 TRUE 0.94
cancer of unknown primary KRAS_G12D KMT2D 42 113 Metastasis -0.01 -0.83 0.76 861.87 1.00 573 35 106 7 FALSE 0.01
cancer of unknown primary KRAS_G12D KMT2D 7 12 Primary -0.08 -1.42 0.99 996.06 1.00 54 6 11 1 FALSE 0.05
colorectal cancer KRAS_G12D KMT2D 111 82 Metastasis -0.95 -1.95 -0.14 1440.81 1.00 714 107 78 4 FALSE 1.43
colorectal cancer KRAS_G12D KMT2D 194 306 Primary -0.28 -0.69 0.08 1391.17 1.00 1002 160 272 34 FALSE 0.82
non-small cell lung cancer KRAS_G12D KMT2D 45 125 Metastasis -1.84 -4.59 -0.50 966.77 1.00 1232 45 125 0 FALSE 1.08
non-small cell lung cancer KRAS_G12D KMT2D 107 203 Primary -1.32 -2.43 -0.34 1631.99 1.00 2019 103 199 4 FALSE 1.80
pancreatic cancer KRAS_G12D KMT2D 201 34 Metastasis 0.10 -0.61 0.73 1234.61 1.00 358 190 23 11 FALSE 0.11
pancreatic cancer KRAS_G12D KMT2D 282 32 Primary 0.34 -0.30 0.99 1520.05 1.00 599 268 18 14 FALSE 0.51
uterine cancer KRAS_G12D KMT2D 22 91 Metastasis 0.24 -0.62 1.17 719.73 1.01 300 14 83 8 FALSE 0.21
uterine cancer KRAS_G12D KMT2D 30 173 Primary -0.55 -1.77 0.32 764.80 1.00 537 27 170 3 FALSE 0.52
cancer of unknown primary KRAS_G12D KMT2D 49 125 Tumor Type:overall -0.03 -1.32 1.10 1342.68 1.00 627 41 117 8 FALSE 0.02
colorectal cancer KRAS_G12D KMT2D 305 388 Tumor Type:overall -0.60 -2.01 0.75 1340.23 1.00 1716 267 350 38 FALSE 0.40
non-small cell lung cancer KRAS_G12D KMT2D 152 328 Tumor Type:overall -1.55 -3.39 -0.27 1265.31 1.00 3251 148 324 4 FALSE 1.29
pancreatic cancer KRAS_G12D KMT2D 483 66 Tumor Type:overall 0.21 -0.80 1.23 1251.11 1.00 957 458 41 25 FALSE 0.18
uterine cancer KRAS_G12D KMT2D 52 264 Tumor Type:overall -0.16 -1.63 1.14 1322.35 1.00 837 41 253 11 FALSE 0.09
colorectal cancer KRAS_G12D TSC2 111 25 Metastasis -0.79 -2.54 0.39 1669.12 1.00 747 110 24 1 TRUE 0.52
colorectal cancer KRAS_G12D TSC2 183 90 Primary 0.08 -0.52 0.65 1300.96 1.00 1098 169 76 14 TRUE 0.11
non-small cell lung cancer KRAS_G12D TSC2 45 28 Metastasis -1.71 -5.05 0.26 1092.72 1.00 1310 45 28 0 TRUE 0.66
non-small cell lung cancer KRAS_G12D TSC2 106 44 Primary -1.49 -4.67 0.30 1122.87 1.00 2152 105 43 1 TRUE 0.65
uterine cancer KRAS_G12D TSC2 21 28 Metastasis 1.29 0.16 2.45 604.55 1.00 340 15 22 6 TRUE 1.50
uterine cancer KRAS_G12D TSC2 30 46 Primary 0.00 -2.09 1.31 1306.15 1.00 611 29 45 1 TRUE 0.00
colorectal cancer KRAS_G12D TSC2 294 115 Tumor Type:overall -0.37 -2.37 1.13 1404.86 1.00 1845 279 100 15 TRUE 0.18
non-small cell lung cancer KRAS_G12D TSC2 151 72 Tumor Type:overall -1.59 -4.77 0.38 1098.89 1.00 3462 150 71 1 TRUE 0.65
uterine cancer KRAS_G12D TSC2 51 74 Tumor Type:overall 0.66 -1.27 2.34 1478.08 1.00 951 44 67 7 TRUE 0.34
cancer of unknown primary KRAS_G12D APC 44 59 Metastasis 0.29 -0.80 1.18 1489.04 1.00 618 39 54 5 TRUE 0.24
colorectal cancer KRAS_G12D APC 173 1010 Metastasis -0.18 -0.57 0.19 1377.94 1.00 239 47 884 126 TRUE 0.45
colorectal cancer KRAS_G12D APC 306 1528 Primary 0.21 -0.07 0.52 1300.28 1.00 474 66 1288 240 TRUE 0.82
non-small cell lung cancer KRAS_G12D APC 47 65 Metastasis -0.24 -1.66 0.75 938.40 1.00 1323 46 64 1 TRUE 0.15
non-small cell lung cancer KRAS_G12D APC 109 92 Primary 0.08 -0.84 0.90 184.69 1.02 2184 103 86 6 TRUE 0.06
uterine cancer KRAS_G12D APC 21 47 Metastasis 0.17 -0.90 1.19 1169.33 1.00 358 17 43 4 TRUE 0.12
uterine cancer KRAS_G12D APC 32 80 Primary -0.09 -1.30 0.82 873.89 1.00 695 30 78 2 TRUE 0.07
cancer of unknown primary KRAS_G12D APC 44 59 Tumor Type:overall 0.21 -4.35 4.48 1418.48 1.00 618 39 54 5 TRUE 0.04
colorectal cancer KRAS_G12D APC 479 2538 Tumor Type:overall 0.01 -0.81 0.74 1714.14 1.00 713 113 2172 366 TRUE 0.01
non-small cell lung cancer KRAS_G12D APC 156 157 Tumor Type:overall -0.08 -1.30 0.96 418.73 1.01 3507 149 150 7 TRUE 0.05
uterine cancer KRAS_G12D APC 53 127 Tumor Type:overall 0.03 -1.19 1.13 1507.72 1.00 1053 47 121 6 TRUE 0.02
colorectal cancer KRAS_G12D ERBB2 128 32 Metastasis -1.75 -5.76 -0.06 1047.15 1.00 798 128 32 0 TRUE 0.59
colorectal cancer KRAS_G12D ERBB2 204 72 Primary -0.35 -1.14 0.38 1002.93 1.00 1234 195 63 9 TRUE 0.43
non-small cell lung cancer KRAS_G12D ERBB2 47 46 Metastasis -1.96 -4.62 0.04 550.91 1.00 1341 46 45 1 TRUE 0.97
non-small cell lung cancer KRAS_G12D ERBB2 109 83 Primary -2.39 -5.76 -0.46 475.73 1.00 2184 109 83 0 TRUE 1.02
uterine cancer KRAS_G12D ERBB2 19 18 Metastasis -0.16 -2.17 1.56 1176.38 1.00 365 17 16 2 TRUE 0.07
uterine cancer KRAS_G12D ERBB2 32 40 Primary -1.02 -4.58 0.71 1145.93 1.00 700 32 40 0 TRUE 0.30
colorectal cancer KRAS_G12D ERBB2 332 104 Tumor Type:overall -0.99 -3.68 0.56 1321.71 1.00 2032 323 95 9 TRUE 0.45
non-small cell lung cancer KRAS_G12D ERBB2 156 129 Tumor Type:overall -2.14 -4.80 -0.16 474.27 1.00 3525 155 128 1 TRUE 1.08
uterine cancer KRAS_G12D ERBB2 51 58 Tumor Type:overall -0.54 -2.75 1.20 1471.74 1.00 1065 49 56 2 TRUE 0.21
colorectal cancer KRAS_G12D JAK1 111 12 Metastasis -0.59 -2.29 0.79 1068.57 1.00 756 110 11 1 TRUE 0.34
colorectal cancer KRAS_G12D JAK1 183 63 Primary -0.30 -1.22 0.44 1131.53 1.00 1116 176 56 7 TRUE 0.32
non-small cell lung cancer KRAS_G12D JAK1 45 20 Metastasis -4.36 -11.80 -0.44 82.06 1.03 1317 45 20 0 TRUE 0.84
non-small cell lung cancer KRAS_G12D JAK1 106 32 Primary -4.35 -11.54 -0.56 76.88 1.03 2163 106 32 0 TRUE 0.84
uterine cancer KRAS_G12D JAK1 20 39 Metastasis 1.06 0.18 2.02 1188.46 1.00 334 14 33 6 TRUE 1.65
uterine cancer KRAS_G12D JAK1 32 106 Primary 0.66 -0.14 1.38 1458.55 1.00 575 25 99 7 TRUE 1.07
colorectal cancer KRAS_G12D JAK1 294 75 Tumor Type:overall -0.47 -2.34 1.12 1317.76 1.00 1872 286 67 8 TRUE 0.23
non-small cell lung cancer KRAS_G12D JAK1 151 52 Tumor Type:overall -4.32 -11.43 -0.37 81.97 1.03 3480 151 52 0 TRUE 0.83
uterine cancer KRAS_G12D JAK1 52 145 Tumor Type:overall 0.86 -0.17 2.04 1485.28 1.00 909 39 132 13 TRUE 0.80
uterine cancer KRAS_G12D CCND1 18 27 Metastasis 0.64 -0.85 1.66 69.59 1.04 336 15 24 3 TRUE 0.56
uterine cancer KRAS_G12D CCND1 30 42 Primary 0.56 -0.80 1.51 77.57 1.03 604 27 39 3 TRUE 0.50
uterine cancer KRAS_G12D CCND1 48 69 Tumor Type:overall 0.60 -0.80 1.65 91.69 1.03 940 42 63 6 TRUE 0.49
colorectal cancer KRAS_G12D ARID2 111 31 Metastasis -0.47 -1.54 0.36 1350.02 1.00 743 109 29 2 FALSE 0.48
colorectal cancer KRAS_G12D ARID2 180 79 Primary -0.19 -0.88 0.44 1391.40 1.00 1101 170 69 10 FALSE 0.24
non-small cell lung cancer KRAS_G12D ARID2 45 74 Metastasis -0.50 -1.89 0.48 1634.74 1.00 1272 44 73 1 FALSE 0.38
non-small cell lung cancer KRAS_G12D ARID2 106 108 Primary -0.27 -1.25 0.54 1534.39 1.00 2096 101 103 5 FALSE 0.25
uterine cancer KRAS_G12D ARID2 20 27 Metastasis 0.76 -0.24 1.85 1252.66 1.00 343 16 23 4 FALSE 0.84
uterine cancer KRAS_G12D ARID2 31 44 Primary 0.43 -0.76 1.36 1401.46 1.00 612 29 42 2 FALSE 0.36
colorectal cancer KRAS_G12D ARID2 291 110 Tumor Type:overall -0.32 -1.44 0.67 1386.54 1.00 1844 279 98 12 FALSE 0.26
non-small cell lung cancer KRAS_G12D ARID2 151 182 Tumor Type:overall -0.39 -1.66 0.66 1479.25 1.00 3368 145 176 6 FALSE 0.28
uterine cancer KRAS_G12D ARID2 51 71 Tumor Type:overall 0.60 -0.59 1.70 1487.74 1.00 955 45 65 6 FALSE 0.48
colorectal cancer KRAS_G12D SOX17 111 30 Metastasis 0.18 -0.57 0.85 1032.63 1.00 744 107 26 4 FALSE 0.20
colorectal cancer KRAS_G12D SOX17 181 68 Primary 0.29 -0.30 0.85 1066.95 1.01 1108 169 56 12 FALSE 0.49
non-small cell lung cancer KRAS_G12D SOX17 45 26 Metastasis -0.88 -3.69 0.80 1213.02 1.00 1311 45 26 0 FALSE 0.33
non-small cell lung cancer KRAS_G12D SOX17 106 35 Primary -0.47 -2.23 0.92 882.48 1.00 2161 104 33 2 FALSE 0.26
colorectal cancer KRAS_G12D SOX17 292 98 Tumor Type:overall 0.25 -0.58 1.04 1066.88 1.01 1852 276 82 16 FALSE 0.25
non-small cell lung cancer KRAS_G12D SOX17 151 61 Tumor Type:overall -0.66 -2.89 0.94 980.01 1.00 3472 149 59 2 FALSE 0.31
colorectal cancer KRAS_G12D MTOR 112 41 Metastasis -0.14 -0.87 0.56 1107.87 1.00 734 107 36 5 TRUE 0.16
colorectal cancer KRAS_G12D MTOR 182 99 Primary -0.14 -0.76 0.41 585.22 1.01 1089 170 87 12 TRUE 0.19
non-small cell lung cancer KRAS_G12D MTOR 45 39 Metastasis -1.11 -3.20 0.49 1087.88 1.00 1300 44 38 1 TRUE 0.65
non-small cell lung cancer KRAS_G12D MTOR 106 76 Primary -1.27 -3.29 0.08 1036.40 1.00 2119 105 75 1 TRUE 0.85
uterine cancer KRAS_G12D MTOR 19 19 Metastasis 0.86 -0.40 2.06 1217.66 1.00 344 16 16 3 TRUE 0.77
uterine cancer KRAS_G12D MTOR 30 71 Primary 0.42 -0.68 1.36 1354.17 1.00 594 26 67 4 TRUE 0.38
colorectal cancer KRAS_G12D MTOR 294 140 Tumor Type:overall -0.14 -0.97 0.79 1284.63 1.00 1823 277 123 17 TRUE 0.11
non-small cell lung cancer KRAS_G12D MTOR 151 115 Tumor Type:overall -1.18 -3.29 0.40 964.20 1.00 3419 149 113 2 TRUE 0.71
uterine cancer KRAS_G12D MTOR 49 90 Tumor Type:overall 0.64 -0.77 2.13 1353.38 1.00 938 42 83 7 TRUE 0.43
non-small cell lung cancer KRAS_G12D RFWD2 45 22 Metastasis -0.75 -3.79 0.90 1030.90 1.00 1315 45 22 0 FALSE 0.24
non-small cell lung cancer KRAS_G12D RFWD2 106 35 Primary -0.33 -2.03 1.02 869.28 1.00 2159 104 33 2 FALSE 0.17
non-small cell lung cancer KRAS_G12D RFWD2 151 57 Tumor Type:overall -0.54 -2.77 1.10 1098.51 1.00 3474 149 55 2 FALSE 0.23
colorectal cancer KRAS_G12D IRS1 112 19 Metastasis -0.20 -1.36 1.03 1414.98 1.00 751 109 16 3 FALSE 0.14
colorectal cancer KRAS_G12D IRS1 180 78 Primary -0.77 -1.64 0.03 1465.68 1.00 1098 175 73 5 FALSE 1.15
non-small cell lung cancer KRAS_G12D IRS1 45 30 Metastasis -4.99 -11.40 -0.87 73.42 1.05 1307 45 30 0 FALSE 1.06
non-small cell lung cancer KRAS_G12D IRS1 106 43 Primary -5.07 -11.41 -1.03 80.43 1.04 2152 106 43 0 FALSE 1.07
colorectal cancer KRAS_G12D IRS1 292 97 Tumor Type:overall -0.47 -1.99 1.18 1371.09 1.00 1849 284 89 8 FALSE 0.24
non-small cell lung cancer KRAS_G12D IRS1 151 73 Tumor Type:overall -4.94 -11.17 -0.89 68.51 1.05 3459 151 73 0 FALSE 1.08
cancer of unknown primary KRAS_G12D NOTCH1 43 47 Metastasis -0.63 -2.52 0.66 1618.97 1.00 623 41 45 2 TRUE 0.37
colorectal cancer KRAS_G12D NOTCH1 128 39 Metastasis -0.84 -2.12 0.04 1208.94 1.00 794 126 37 2 TRUE 0.89
colorectal cancer KRAS_G12D NOTCH1 208 133 Primary -0.31 -0.91 0.24 1506.40 1.00 1207 193 118 15 TRUE 0.54
non-small cell lung cancer KRAS_G12D NOTCH1 47 52 Metastasis -0.13 -1.53 1.10 1137.65 1.00 1339 44 49 3 TRUE 0.07
non-small cell lung cancer KRAS_G12D NOTCH1 109 78 Primary -0.70 -2.46 0.47 851.83 1.00 2192 108 77 1 TRUE 0.46
uterine cancer KRAS_G12D NOTCH1 18 34 Metastasis -0.38 -1.92 0.92 265.96 1.01 355 16 32 2 TRUE 0.22
uterine cancer KRAS_G12D NOTCH1 32 56 Primary -0.60 -2.18 0.63 430.16 1.01 699 31 55 1 TRUE 0.39
cancer of unknown primary KRAS_G12D NOTCH1 43 47 Tumor Type:overall -0.45 -4.76 4.34 1545.23 1.00 623 41 45 2 TRUE 0.08
colorectal cancer KRAS_G12D NOTCH1 336 172 Tumor Type:overall -0.57 -2.04 0.64 1342.17 1.00 2001 319 155 17 TRUE 0.40
non-small cell lung cancer KRAS_G12D NOTCH1 156 130 Tumor Type:overall -0.42 -2.03 0.93 1103.96 1.00 3531 152 126 4 TRUE 0.22
uterine cancer KRAS_G12D NOTCH1 50 90 Tumor Type:overall -0.49 -2.08 0.85 245.88 1.01 1054 47 87 3 TRUE 0.28
colorectal cancer KRAS_G12D NTRK1 111 16 Metastasis -0.51 -1.86 0.62 1254.55 1.01 752 110 15 1 TRUE 0.38
colorectal cancer KRAS_G12D NTRK1 181 48 Primary -0.27 -1.18 0.59 132.87 1.03 1121 175 42 6 TRUE 0.25
non-small cell lung cancer KRAS_G12D NTRK1 45 44 Metastasis -1.52 -4.15 0.40 1032.94 1.00 1295 44 43 1 TRUE 0.70
non-small cell lung cancer KRAS_G12D NTRK1 106 44 Primary -2.00 -5.37 0.04 961.99 1.00 2149 106 44 0 TRUE 0.82
colorectal cancer KRAS_G12D NTRK1 292 64 Tumor Type:overall -0.40 -1.82 0.72 788.62 1.01 1873 285 57 7 TRUE 0.26
non-small cell lung cancer KRAS_G12D NTRK1 151 88 Tumor Type:overall -1.71 -4.51 0.36 1070.85 1.00 3444 150 87 1 TRUE 0.72
non-small cell lung cancer KRAS_G12D INPP4A 45 21 Metastasis -4.65 -11.54 -0.41 518.83 1.00 1317 45 21 0 FALSE 0.92
non-small cell lung cancer KRAS_G12D INPP4A 106 32 Primary -4.67 -11.37 -0.66 514.28 1.00 2160 106 32 0 FALSE 0.94
non-small cell lung cancer KRAS_G12D INPP4A 151 53 Tumor Type:overall -4.60 -11.55 -0.51 488.43 1.00 3477 151 53 0 FALSE 0.93
colorectal cancer KRAS_G12D CASP8 111 17 Metastasis -0.30 -1.71 0.83 1601.86 1.00 754 109 15 2 FALSE 0.20
colorectal cancer KRAS_G12D CASP8 181 79 Primary -0.24 -1.00 0.39 1441.07 1.00 1102 172 70 9 FALSE 0.30
colorectal cancer KRAS_G12D CASP8 292 96 Tumor Type:overall -0.25 -1.73 1.18 1429.12 1.00 1856 281 85 11 FALSE 0.13
colorectal cancer KRAS_G12D SETD2 112 29 Metastasis -0.91 -2.14 0.18 1472.91 1.00 744 110 27 2 FALSE 0.95
colorectal cancer KRAS_G12D SETD2 181 84 Primary -0.96 -1.93 -0.15 1266.68 1.00 1097 176 79 5 FALSE 1.50
non-small cell lung cancer KRAS_G12D SETD2 46 93 Metastasis -0.12 -1.07 0.70 1438.91 1.00 1263 43 90 3 FALSE 0.10
non-small cell lung cancer KRAS_G12D SETD2 107 132 Primary -0.09 -0.96 0.62 1506.19 1.00 2082 101 126 6 FALSE 0.09
uterine cancer KRAS_G12D SETD2 20 27 Metastasis 0.13 -1.27 1.39 1275.67 1.00 339 17 24 3 FALSE 0.07
uterine cancer KRAS_G12D SETD2 30 62 Primary -0.39 -2.02 0.84 1422.47 1.00 601 29 61 1 FALSE 0.24
colorectal cancer KRAS_G12D SETD2 293 113 Tumor Type:overall -0.92 -2.27 0.35 1535.96 1.00 1841 286 106 7 FALSE 0.75
non-small cell lung cancer KRAS_G12D SETD2 153 225 Tumor Type:overall -0.11 -1.18 0.80 1466.87 1.00 3345 144 216 9 FALSE 0.08
uterine cancer KRAS_G12D SETD2 50 89 Tumor Type:overall -0.12 -1.68 1.38 1294.86 1.00 940 46 85 4 FALSE 0.06
colorectal cancer KRAS_G12D PBRM1 113 15 Metastasis 0.51 -0.61 1.63 1495.73 1.00 756 109 11 4 TRUE 0.42
colorectal cancer KRAS_G12D PBRM1 181 79 Primary -0.15 -0.93 0.52 1505.32 1.00 1101 172 70 9 TRUE 0.16
non-small cell lung cancer KRAS_G12D PBRM1 45 54 Metastasis -0.23 -1.83 0.87 1442.93 1.00 1292 44 53 1 TRUE 0.13
non-small cell lung cancer KRAS_G12D PBRM1 106 60 Primary 0.09 -1.00 1.00 1396.64 1.00 2143 102 56 4 TRUE 0.06
colorectal cancer KRAS_G12D PBRM1 294 94 Tumor Type:overall 0.15 -1.65 1.92 1471.53 1.00 1857 281 81 13 TRUE 0.06
non-small cell lung cancer KRAS_G12D PBRM1 151 114 Tumor Type:overall -0.08 -1.49 1.18 1452.12 1.00 3435 146 109 5 TRUE 0.04
colorectal cancer KRAS_G12D EPHA3 111 34 Metastasis -0.72 -1.69 0.16 1175.19 1.00 737 108 31 3 FALSE 0.92
colorectal cancer KRAS_G12D EPHA3 180 79 Primary -0.81 -1.64 -0.10 1371.42 1.00 1097 175 74 5 FALSE 1.34
non-small cell lung cancer KRAS_G12D EPHA3 45 83 Metastasis -0.78 -2.05 0.22 1193.06 1.00 1260 44 82 1 FALSE 0.78
non-small cell lung cancer KRAS_G12D EPHA3 106 159 Primary -0.63 -1.53 0.20 1318.20 1.00 2054 101 154 5 FALSE 0.83
uterine cancer KRAS_G12D EPHA3 18 22 Metastasis 0.58 -0.70 1.77 1278.77 1.00 347 15 19 3 FALSE 0.44
uterine cancer KRAS_G12D EPHA3 30 56 Primary 0.16 -1.17 1.18 1058.07 1.00 608 28 54 2 FALSE 0.10
colorectal cancer KRAS_G12D EPHA3 291 113 Tumor Type:overall -0.78 -1.84 0.11 1310.08 1.00 1834 283 105 8 FALSE 0.90
non-small cell lung cancer KRAS_G12D EPHA3 151 242 Tumor Type:overall -0.68 -1.84 0.30 1186.69 1.00 3314 145 236 6 FALSE 0.65
uterine cancer KRAS_G12D EPHA3 48 78 Tumor Type:overall 0.40 -1.04 1.77 1169.33 1.00 955 43 73 5 FALSE 0.24
colorectal cancer KRAS_G12D KIT 128 17 Metastasis -0.83 -2.21 0.24 339.88 1.01 810 127 16 1 TRUE 0.70
colorectal cancer KRAS_G12D KIT 204 37 Primary -0.77 -2.02 0.20 317.69 1.01 1263 201 34 3 TRUE 0.72
non-small cell lung cancer KRAS_G12D KIT 47 30 Metastasis -4.45 -11.44 -0.70 24.12 1.19 1354 47 30 0 TRUE 0.84
non-small cell lung cancer KRAS_G12D KIT 109 51 Primary -4.50 -11.59 -0.74 23.64 1.19 2216 109 51 0 TRUE 0.85
colorectal cancer KRAS_G12D KIT 332 54 Tumor Type:overall -0.80 -2.14 0.21 371.82 1.01 2073 328 50 4 TRUE 0.67
non-small cell lung cancer KRAS_G12D KIT 156 81 Tumor Type:overall -4.44 -11.42 -0.72 23.63 1.19 3570 156 81 0 TRUE 0.85
colorectal cancer KRAS_G12D KDR 128 15 Metastasis -0.52 -1.89 0.73 1425.79 1.00 813 126 13 2 TRUE 0.36
colorectal cancer KRAS_G12D KDR 205 60 Primary -0.79 -1.84 0.08 1374.05 1.00 1247 201 56 4 TRUE 0.94
non-small cell lung cancer KRAS_G12D KDR 47 51 Metastasis -1.01 -4.41 0.42 959.81 1.00 1335 47 51 0 TRUE 0.38
non-small cell lung cancer KRAS_G12D KDR 110 103 Primary -0.30 -1.37 0.60 1458.47 1.00 2171 105 98 5 TRUE 0.26
colorectal cancer KRAS_G12D KDR 333 75 Tumor Type:overall -0.61 -2.01 0.95 1391.65 1.00 2060 327 69 6 TRUE 0.36
non-small cell lung cancer KRAS_G12D KDR 157 154 Tumor Type:overall -0.64 -2.91 0.72 1072.25 1.00 3506 152 149 5 TRUE 0.31
colorectal cancer KRAS_G12D RICTOR 111 11 Metastasis -1.12 -3.20 0.63 1341.29 1.00 759 110 10 1 FALSE 0.62
colorectal cancer KRAS_G12D RICTOR 181 59 Primary -1.57 -3.00 -0.41 1478.73 1.00 1112 179 57 2 FALSE 1.72
non-small cell lung cancer KRAS_G12D RICTOR 45 24 Metastasis -1.41 -4.02 0.70 304.55 1.02 1315 44 23 1 FALSE 0.59
non-small cell lung cancer KRAS_G12D RICTOR 106 40 Primary -1.88 -5.18 0.14 1134.51 1.00 2154 106 40 0 FALSE 0.77
uterine cancer KRAS_G12D RICTOR 18 14 Metastasis 1.01 -0.78 2.66 557.18 1.01 349 15 11 3 FALSE 0.57
uterine cancer KRAS_G12D RICTOR 30 42 Primary -1.48 -6.94 0.63 829.13 1.00 614 30 42 0 FALSE 0.36
colorectal cancer KRAS_G12D RICTOR 292 70 Tumor Type:overall -1.31 -3.45 0.73 1456.76 1.00 1871 289 67 3 FALSE 0.70
non-small cell lung cancer KRAS_G12D RICTOR 151 64 Tumor Type:overall -1.62 -4.24 0.49 669.61 1.01 3469 150 63 1 FALSE 0.71
uterine cancer KRAS_G12D RICTOR 48 56 Tumor Type:overall -0.23 -3.70 2.35 1227.93 1.00 963 45 53 3 FALSE 0.06
colorectal cancer KRAS_G12D RAD50 111 18 Metastasis -0.40 -1.57 0.66 1452.38 1.00 754 109 16 2 FALSE 0.32
colorectal cancer KRAS_G12D RAD50 180 42 Primary -0.42 -1.49 0.50 1469.63 1.00 1127 176 38 4 FALSE 0.41
colorectal cancer KRAS_G12D RAD50 291 60 Tumor Type:overall -0.41 -1.62 0.80 1573.12 1.00 1881 285 54 6 FALSE 0.28
colorectal cancer KRAS_G12D CSF1R 128 18 Metastasis -0.91 -2.17 0.14 681.99 1.00 813 127 17 1 TRUE 0.87
colorectal cancer KRAS_G12D CSF1R 204 38 Primary -0.83 -2.02 0.12 734.79 1.01 1261 201 35 3 TRUE 0.90
non-small cell lung cancer KRAS_G12D CSF1R 47 31 Metastasis -1.86 -4.88 0.25 265.40 1.02 1355 47 31 0 TRUE 0.78
non-small cell lung cancer KRAS_G12D CSF1R 109 38 Primary -1.63 -4.37 0.35 72.98 1.05 2228 108 37 1 TRUE 0.74
colorectal cancer KRAS_G12D CSF1R 332 56 Tumor Type:overall -0.86 -2.16 0.22 931.40 1.00 2074 328 52 4 TRUE 0.76
non-small cell lung cancer KRAS_G12D CSF1R 156 69 Tumor Type:overall -1.76 -4.53 0.44 120.33 1.03 3583 155 68 1 TRUE 0.73
non-small cell lung cancer KRAS_G12D PARK2 45 31 Metastasis -0.54 -2.45 1.00 733.31 1.00 1307 44 30 1 FALSE 0.26
non-small cell lung cancer KRAS_G12D PARK2 106 34 Primary -0.63 -2.34 0.73 770.26 1.00 2159 105 33 1 FALSE 0.34
non-small cell lung cancer KRAS_G12D PARK2 151 65 Tumor Type:overall -0.58 -2.49 0.99 950.33 1.00 3466 149 63 2 FALSE 0.27
non-small cell lung cancer KRAS_G12D NTRK2 45 22 Metastasis -1.64 -5.00 0.46 1342.56 1.00 1317 45 22 0 FALSE 0.61
non-small cell lung cancer KRAS_G12D NTRK2 106 45 Primary -1.44 -4.15 0.35 1097.97 1.00 2151 105 44 1 FALSE 0.66
non-small cell lung cancer KRAS_G12D NTRK2 151 67 Tumor Type:overall -1.51 -4.58 0.58 1242.42 1.00 3468 150 66 1 FALSE 0.60
colorectal cancer KRAS_G12D PTCH1 111 38 Metastasis -0.34 -1.27 0.59 1309.25 1.00 743 106 33 5 TRUE 0.30
colorectal cancer KRAS_G12D PTCH1 180 107 Primary -0.85 -1.64 -0.15 1244.99 1.00 1084 174 101 6 TRUE 1.55
non-small cell lung cancer KRAS_G12D PTCH1 45 27 Metastasis -0.89 -3.59 0.78 1123.20 1.00 1311 45 27 0 TRUE 0.32
non-small cell lung cancer KRAS_G12D PTCH1 106 35 Primary -0.46 -2.40 1.04 987.85 1.00 2159 104 33 2 TRUE 0.23
uterine cancer KRAS_G12D PTCH1 18 14 Metastasis -0.16 -2.08 1.34 1350.63 1.00 348 17 13 1 TRUE 0.07
uterine cancer KRAS_G12D PTCH1 30 55 Primary -0.29 -1.72 0.89 1341.28 1.00 603 28 53 2 TRUE 0.17
colorectal cancer KRAS_G12D PTCH1 291 145 Tumor Type:overall -0.58 -1.76 0.78 1261.58 1.00 1827 280 134 11 TRUE 0.41
non-small cell lung cancer KRAS_G12D PTCH1 151 62 Tumor Type:overall -0.64 -2.96 1.01 1083.77 1.00 3470 149 60 2 TRUE 0.29
uterine cancer KRAS_G12D PTCH1 48 69 Tumor Type:overall -0.21 -2.05 1.47 1275.41 1.00 951 45 66 3 TRUE 0.09
colorectal cancer KRAS_G12D TET1 111 35 Metastasis -0.87 -1.91 0.03 662.01 1.00 743 109 33 2 FALSE 1.12
colorectal cancer KRAS_G12D TET1 180 68 Primary -0.80 -1.68 -0.01 561.64 1.00 1114 175 63 5 FALSE 1.20
non-small cell lung cancer KRAS_G12D TET1 45 58 Metastasis -2.25 -5.50 -0.32 762.36 1.01 1286 45 58 0 FALSE 1.03
non-small cell lung cancer KRAS_G12D TET1 106 68 Primary -1.99 -4.93 -0.25 655.48 1.01 2130 105 67 1 FALSE 1.07
colorectal cancer KRAS_G12D TET1 291 103 Tumor Type:overall -0.83 -1.87 0.08 687.88 1.00 1857 284 96 7 FALSE 0.99
non-small cell lung cancer KRAS_G12D TET1 151 126 Tumor Type:overall -2.07 -5.10 -0.08 871.15 1.01 3416 150 125 1 FALSE 1.01
colorectal cancer KRAS_G12D FGFR2 128 19 Metastasis -1.69 -3.39 -0.25 237.19 1.03 808 127 18 1 TRUE 1.55
colorectal cancer KRAS_G12D FGFR2 204 34 Primary -1.72 -3.40 -0.35 278.37 1.03 1264 203 33 1 TRUE 1.61
uterine cancer KRAS_G12D FGFR2 18 23 Metastasis -1.53 -4.75 0.35 1285.80 1.00 359 18 23 0 TRUE 0.58
uterine cancer KRAS_G12D FGFR2 32 80 Primary -1.04 -2.85 0.30 1195.55 1.00 666 30 78 2 TRUE 0.66
colorectal cancer KRAS_G12D FGFR2 332 53 Tumor Type:overall -1.70 -3.43 -0.28 229.18 1.03 2072 330 51 2 TRUE 1.48
uterine cancer KRAS_G12D FGFR2 50 103 Tumor Type:overall -1.24 -3.73 0.64 1279.44 1.00 1025 48 101 2 TRUE 0.59
colorectal cancer KRAS_G12D TBX3 111 18 Metastasis -0.06 -1.17 1.03 1416.40 1.00 753 108 15 3 FALSE 0.04
colorectal cancer KRAS_G12D TBX3 180 62 Primary -0.31 -1.17 0.42 1403.95 1.00 1117 174 56 6 FALSE 0.36
non-small cell lung cancer KRAS_G12D TBX3 45 60 Metastasis -2.09 -5.43 -0.02 48.08 1.08 1283 45 60 0 FALSE 0.83
non-small cell lung cancer KRAS_G12D TBX3 106 77 Primary -1.90 -4.62 0.05 36.71 1.09 2119 105 76 1 FALSE 0.92
uterine cancer KRAS_G12D TBX3 18 12 Metastasis -0.30 -2.51 1.45 730.92 1.01 348 17 11 1 FALSE 0.12
uterine cancer KRAS_G12D TBX3 30 42 Primary -0.56 -2.57 0.88 594.38 1.01 612 29 41 1 FALSE 0.29
colorectal cancer KRAS_G12D TBX3 291 80 Tumor Type:overall -0.18 -1.45 1.29 1451.61 1.00 1870 282 71 9 FALSE 0.11
non-small cell lung cancer KRAS_G12D TBX3 151 137 Tumor Type:overall -1.98 -4.90 0.05 39.78 1.08 3402 150 136 1 FALSE 0.86
uterine cancer KRAS_G12D TBX3 48 54 Tumor Type:overall -0.44 -2.68 1.31 736.90 1.01 960 46 52 2 FALSE 0.18
colorectal cancer KRAS_G12D HNF1A 204 43 Primary -0.07 -1.07 0.76 1429.64 1.00 1257 198 37 6 TRUE 0.06
colorectal cancer KRAS_G12D HNF1A 204 43 Tumor Type:overall -0.06 -4.52 4.34 1439.46 1.00 1257 198 37 6 TRUE 0.01
colorectal cancer KRAS_G12D DICER1 111 27 Metastasis -0.65 -1.63 0.20 655.48 1.00 747 109 25 2 TRUE 0.78
colorectal cancer KRAS_G12D DICER1 180 49 Primary -0.64 -1.58 0.18 639.26 1.00 1125 176 45 4 TRUE 0.81
non-small cell lung cancer KRAS_G12D DICER1 45 33 Metastasis -1.95 -4.86 0.06 1149.70 1.00 1307 45 33 0 TRUE 0.85
non-small cell lung cancer KRAS_G12D DICER1 106 57 Primary -1.75 -4.34 0.08 1064.02 1.00 2139 105 56 1 TRUE 0.88
uterine cancer KRAS_G12D DICER1 18 18 Metastasis -1.32 -4.24 0.50 1315.60 1.00 348 18 18 0 TRUE 0.57
uterine cancer KRAS_G12D DICER1 31 63 Primary -0.91 -2.82 0.50 1375.90 1.00 600 29 61 2 TRUE 0.56
colorectal cancer KRAS_G12D DICER1 291 76 Tumor Type:overall -0.66 -1.75 0.22 773.64 1.00 1872 285 70 6 TRUE 0.73
non-small cell lung cancer KRAS_G12D DICER1 151 90 Tumor Type:overall -1.82 -4.57 0.22 1156.52 1.00 3446 150 89 1 TRUE 0.84
uterine cancer KRAS_G12D DICER1 49 81 Tumor Type:overall -1.08 -3.32 0.81 1424.82 1.00 948 47 79 2 TRUE 0.52
colorectal cancer KRAS_G12D SMAD3 111 38 Metastasis -2.64 -8.47 0.33 823.46 1.00 732 111 38 0 TRUE 0.63
colorectal cancer KRAS_G12D SMAD3 186 69 Primary 0.67 0.05 1.23 1551.45 1.00 1114 169 52 17 TRUE 1.60
colorectal cancer KRAS_G12D SMAD3 297 107 Tumor Type:overall -0.87 -4.74 1.91 1286.60 1.00 1846 280 90 17 TRUE 0.23
colorectal cancer KRAS_G12D NTRK3 111 15 Metastasis -0.87 -2.64 0.45 1304.50 1.00 755 110 14 1 FALSE 0.60
colorectal cancer KRAS_G12D NTRK3 180 55 Primary -0.79 -1.95 0.08 1734.36 1.00 1116 176 51 4 FALSE 0.93
non-small cell lung cancer KRAS_G12D NTRK3 45 81 Metastasis -1.06 -2.51 0.34 1435.16 1.00 1264 43 79 2 FALSE 0.86
non-small cell lung cancer KRAS_G12D NTRK3 106 126 Primary -1.36 -2.89 -0.28 1129.49 1.00 2087 105 125 1 FALSE 1.32
colorectal cancer KRAS_G12D NTRK3 291 70 Tumor Type:overall -0.80 -2.35 0.72 1398.34 1.00 1871 286 65 5 FALSE 0.49
non-small cell lung cancer KRAS_G12D NTRK3 151 207 Tumor Type:overall -1.20 -2.68 0.11 888.20 1.00 3351 148 204 3 FALSE 0.99
colorectal cancer KRAS_G12D AXIN1 111 17 Metastasis -0.41 -1.97 0.69 1268.54 1.00 754 110 16 1 FALSE 0.26
colorectal cancer KRAS_G12D AXIN1 182 54 Primary 0.12 -0.62 0.81 1164.46 1.00 1120 173 45 9 FALSE 0.12
colorectal cancer KRAS_G12D AXIN1 293 71 Tumor Type:overall -0.14 -1.58 1.22 1362.68 1.00 1874 283 61 10 FALSE 0.07
colorectal cancer KRAS_G12D GRIN2A 111 41 Metastasis -0.23 -1.04 0.59 1310.67 1.00 733 105 35 6 FALSE 0.24
colorectal cancer KRAS_G12D GRIN2A 180 95 Primary -0.65 -1.46 -0.01 1371.95 1.00 1085 174 89 6 FALSE 1.10
non-small cell lung cancer KRAS_G12D GRIN2A 46 80 Metastasis -0.05 -1.04 0.81 1474.38 1.00 1263 43 77 3 FALSE 0.04
non-small cell lung cancer KRAS_G12D GRIN2A 106 113 Primary -0.08 -0.96 0.65 1307.00 1.00 2092 101 108 5 FALSE 0.07
uterine cancer KRAS_G12D GRIN2A 18 20 Metastasis -1.52 -4.26 0.67 1168.61 1.00 345 17 19 1 FALSE 0.65
uterine cancer KRAS_G12D GRIN2A 30 57 Primary -2.09 -5.44 -0.06 1289.32 1.00 604 30 57 0 FALSE 0.85
colorectal cancer KRAS_G12D GRIN2A 291 136 Tumor Type:overall -0.45 -1.63 0.54 1393.55 1.00 1818 279 124 12 FALSE 0.40
non-small cell lung cancer KRAS_G12D GRIN2A 152 193 Tumor Type:overall -0.07 -1.20 0.88 1334.60 1.00 3355 144 185 8 FALSE 0.05
uterine cancer KRAS_G12D GRIN2A 48 77 Tumor Type:overall -1.76 -4.66 0.35 1163.93 1.00 949 47 76 1 FALSE 0.76
colorectal cancer KRAS_G12D PALB2 180 47 Primary -2.38 -5.06 -0.65 1479.99 1.00 1119 179 46 1 TRUE 1.43
non-small cell lung cancer KRAS_G12D PALB2 45 28 Metastasis -0.44 -2.42 1.13 1270.64 1.00 1313 44 27 1 TRUE 0.21
non-small cell lung cancer KRAS_G12D PALB2 106 32 Primary -0.55 -2.52 0.89 1071.51 1.00 2161 105 31 1 TRUE 0.28
colorectal cancer KRAS_G12D PALB2 180 47 Tumor Type:overall -2.00 -6.32 2.91 1240.27 1.00 1119 179 46 1 TRUE 0.42
non-small cell lung cancer KRAS_G12D PALB2 151 60 Tumor Type:overall -0.49 -2.47 1.08 1048.03 1.00 3474 149 58 2 TRUE 0.22
colorectal cancer KRAS_G12D CTCF 111 24 Metastasis 0.26 -0.56 1.05 1281.84 1.00 751 107 20 4 FALSE 0.28
colorectal cancer KRAS_G12D CTCF 181 66 Primary 0.27 -0.38 0.90 1031.91 1.00 1114 170 55 11 FALSE 0.42
uterine cancer KRAS_G12D CTCF 18 45 Metastasis -1.35 -5.47 0.71 894.66 1.01 315 18 45 0 FALSE 0.34
uterine cancer KRAS_G12D CTCF 31 123 Primary 0.61 -0.25 1.41 710.69 1.01 548 21 113 10 FALSE 0.82
colorectal cancer KRAS_G12D CTCF 292 90 Tumor Type:overall 0.25 -0.64 1.14 1247.14 1.00 1865 277 75 15 FALSE 0.20
uterine cancer KRAS_G12D CTCF 49 168 Tumor Type:overall -0.33 -3.53 1.69 1122.40 1.00 863 39 158 10 FALSE 0.10
colorectal cancer KRAS_G12D CDH1 128 13 Metastasis -0.86 -1.91 0.40 4.61 1.23 816 127 12 1 TRUE 0.69
colorectal cancer KRAS_G12D CDH1 205 41 Primary -0.77 -1.56 0.36 3.05 1.40 1261 201 37 4 TRUE 0.67
colorectal cancer KRAS_G12D CDH1 333 54 Tumor Type:overall -0.82 -1.88 0.50 4.29 1.24 2077 328 49 5 TRUE 0.60
colorectal cancer KRAS_G12D CDK12 111 21 Metastasis -1.74 -5.66 0.05 1333.83 1.00 751 111 21 0 FALSE 0.57
colorectal cancer KRAS_G12D CDK12 181 69 Primary -0.21 -1.00 0.48 1430.70 1.00 1109 172 60 9 FALSE 0.25
non-small cell lung cancer KRAS_G12D CDK12 45 24 Metastasis -1.24 -4.22 0.77 769.50 1.00 1314 44 23 1 FALSE 0.49
non-small cell lung cancer KRAS_G12D CDK12 106 35 Primary -1.70 -4.96 0.20 1178.56 1.00 2159 106 35 0 FALSE 0.63
colorectal cancer KRAS_G12D CDK12 292 90 Tumor Type:overall -0.90 -3.65 0.78 1273.12 1.00 1860 283 81 9 FALSE 0.39
non-small cell lung cancer KRAS_G12D CDK12 151 59 Tumor Type:overall -1.43 -4.54 0.62 895.92 1.00 3473 150 58 1 FALSE 0.57
cancer of unknown primary KRAS_G12D STK11 42 51 Metastasis -6.23 -17.53 -0.81 608.66 1.00 612 42 51 0 TRUE 0.39
non-small cell lung cancer KRAS_G12D STK11 48 205 Metastasis 0.75 0.12 1.44 1379.79 1.00 1196 33 190 15 TRUE 1.62
non-small cell lung cancer KRAS_G12D STK11 109 338 Primary 0.18 -0.39 0.68 1389.76 1.00 1958 93 322 16 TRUE 0.29
cancer of unknown primary KRAS_G12D STK11 42 51 Tumor Type:overall -4.23 -11.10 2.65 1455.93 1.00 612 42 51 0 TRUE 0.65
non-small cell lung cancer KRAS_G12D STK11 157 543 Tumor Type:overall 0.47 -0.48 1.70 1416.03 1.00 3154 126 512 31 TRUE 0.43
colorectal cancer KRAS_G12D DNMT1 113 27 Metastasis -0.12 -1.20 0.98 383.80 1.00 747 108 22 5 FALSE 0.08
colorectal cancer KRAS_G12D DNMT1 180 63 Primary -0.80 -1.95 0.05 1289.78 1.00 1107 177 60 3 FALSE 0.90
colorectal cancer KRAS_G12D DNMT1 293 90 Tumor Type:overall -0.44 -1.70 0.89 1184.12 1.00 1854 285 82 8 FALSE 0.28
colorectal cancer KRAS_G12D BRD4 112 22 Metastasis -0.36 -1.57 0.61 935.59 1.00 749 110 20 2 FALSE 0.29
colorectal cancer KRAS_G12D BRD4 181 66 Primary -0.21 -0.99 0.48 1447.09 1.00 1106 173 58 8 FALSE 0.24
non-small cell lung cancer KRAS_G12D BRD4 45 27 Metastasis -4.80 -12.23 -0.36 953.61 1.00 1312 45 27 0 FALSE 0.92
non-small cell lung cancer KRAS_G12D BRD4 106 26 Primary -4.81 -11.97 -0.55 913.19 1.00 2166 106 26 0 FALSE 0.93
uterine cancer KRAS_G12D BRD4 19 18 Metastasis 0.28 -1.06 1.61 1352.59 1.00 342 17 16 2 FALSE 0.17
uterine cancer KRAS_G12D BRD4 30 52 Primary 0.01 -1.28 1.06 1390.01 1.00 606 28 50 2 FALSE 0.01
colorectal cancer KRAS_G12D BRD4 293 88 Tumor Type:overall -0.29 -1.40 0.80 1496.40 1.00 1855 283 78 10 FALSE 0.21
non-small cell lung cancer KRAS_G12D BRD4 151 53 Tumor Type:overall -4.72 -11.66 -0.37 939.39 1.00 3478 151 53 0 FALSE 0.94
uterine cancer KRAS_G12D BRD4 49 70 Tumor Type:overall 0.14 -1.36 1.48 1487.85 1.00 948 45 66 4 FALSE 0.07
colorectal cancer KRAS_G12D ASXL1 111 34 Metastasis -1.22 -2.33 -0.14 45.91 1.07 735 110 33 1 TRUE 1.56
colorectal cancer KRAS_G12D ASXL1 180 75 Primary -1.07 -1.86 -0.18 20.29 1.12 1100 175 70 5 TRUE 1.70
non-small cell lung cancer KRAS_G12D ASXL1 45 44 Metastasis -0.83 -2.89 0.74 1282.47 1.00 1307 44 43 1 TRUE 0.43
non-small cell lung cancer KRAS_G12D ASXL1 106 42 Primary -0.90 -2.90 0.61 1323.40 1.00 2152 105 41 1 TRUE 0.48
uterine cancer KRAS_G12D ASXL1 20 24 Metastasis 0.75 -1.00 2.07 497.00 1.00 343 16 20 4 TRUE 0.53
uterine cancer KRAS_G12D ASXL1 30 36 Primary -0.84 -5.22 1.02 681.86 1.01 616 30 36 0 TRUE 0.19
colorectal cancer KRAS_G12D ASXL1 291 109 Tumor Type:overall -1.14 -2.18 -0.13 41.02 1.07 1835 285 103 6 TRUE 1.39
non-small cell lung cancer KRAS_G12D ASXL1 151 86 Tumor Type:overall -0.85 -2.95 0.84 1399.11 1.00 3459 149 84 2 TRUE 0.41
uterine cancer KRAS_G12D ASXL1 50 60 Tumor Type:overall 0.02 -2.80 2.04 871.24 1.01 959 46 56 4 TRUE 0.01
colorectal cancer KRAS_G12D EP300 112 38 Metastasis -0.47 -1.40 0.51 1472.21 1.00 739 107 33 5 TRUE 0.49
colorectal cancer KRAS_G12D EP300 180 87 Primary -0.92 -1.95 -0.17 1117.51 1.00 1096 176 83 4 TRUE 1.44
non-small cell lung cancer KRAS_G12D EP300 45 57 Metastasis -0.66 -2.44 0.61 1353.96 1.00 1287 44 56 1 TRUE 0.41
non-small cell lung cancer KRAS_G12D EP300 106 51 Primary -0.50 -1.98 0.67 1642.55 1.00 2148 104 49 2 TRUE 0.34
uterine cancer KRAS_G12D EP300 19 30 Metastasis 0.02 -1.43 1.29 1022.12 1.00 336 16 27 3 TRUE 0.01
uterine cancer KRAS_G12D EP300 30 73 Primary -0.52 -2.33 0.64 906.36 1.00 593 29 72 1 TRUE 0.33
colorectal cancer KRAS_G12D EP300 292 125 Tumor Type:overall -0.69 -1.92 0.34 1534.33 1.00 1835 283 116 9 TRUE 0.62
non-small cell lung cancer KRAS_G12D EP300 151 108 Tumor Type:overall -0.56 -2.53 1.00 1722.66 1.00 3435 148 105 3 TRUE 0.28
uterine cancer KRAS_G12D EP300 49 103 Tumor Type:overall -0.27 -1.88 1.03 1228.11 1.00 929 45 99 4 TRUE 0.15
colorectal cancer KRAS_G12D ERBB4 128 50 Metastasis -0.25 -0.94 0.32 830.46 1.00 782 124 46 4 TRUE 0.36
colorectal cancer KRAS_G12D ERBB4 204 88 Primary -0.13 -0.65 0.45 280.28 1.02 1235 191 75 13 TRUE 0.19
non-small cell lung cancer KRAS_G12D ERBB4 47 88 Metastasis -0.19 -1.38 0.71 1407.35 1.00 1312 45 86 2 TRUE 0.14
non-small cell lung cancer KRAS_G12D ERBB4 109 105 Primary 0.05 -0.77 0.80 1416.25 1.00 2180 103 99 6 TRUE 0.04
colorectal cancer KRAS_G12D ERBB4 332 138 Tumor Type:overall -0.19 -0.82 0.42 868.10 1.00 2017 315 121 17 TRUE 0.24
non-small cell lung cancer KRAS_G12D ERBB4 156 193 Tumor Type:overall -0.07 -1.23 0.96 1478.76 1.00 3492 148 185 8 TRUE 0.04
colorectal cancer KRAS_G12D MDC1 111 13 Metastasis -0.77 -2.41 0.53 1385.08 1.00 755 110 12 1 FALSE 0.53
colorectal cancer KRAS_G12D MDC1 180 52 Primary -0.70 -1.71 0.16 1440.98 1.00 1121 176 48 4 FALSE 0.79
non-small cell lung cancer KRAS_G12D MDC1 45 60 Metastasis -1.84 -5.80 0.30 1244.89 1.00 1288 45 60 0 FALSE 0.58
non-small cell lung cancer KRAS_G12D MDC1 106 35 Primary -0.48 -2.51 1.03 1486.17 1.00 2159 104 33 2 FALSE 0.22
colorectal cancer KRAS_G12D MDC1 291 65 Tumor Type:overall -0.73 -2.40 0.75 1496.53 1.00 1876 286 60 5 FALSE 0.46
non-small cell lung cancer KRAS_G12D MDC1 151 95 Tumor Type:overall -1.10 -4.12 1.09 1394.83 1.00 3447 149 93 2 FALSE 0.40
colorectal cancer KRAS_G12D RECQL4 111 20 Metastasis -0.01 -1.29 0.92 1301.18 1.00 752 109 18 2 TRUE 0.01
colorectal cancer KRAS_G12D RECQL4 180 61 Primary 0.38 -0.27 1.01 1411.99 1.00 1119 168 49 12 TRUE 0.62
non-small cell lung cancer KRAS_G12D RECQL4 45 23 Metastasis -5.16 -11.90 -0.64 99.70 1.03 1314 45 23 0 TRUE 1.19
non-small cell lung cancer KRAS_G12D RECQL4 106 41 Primary -5.25 -12.09 -0.82 112.38 1.03 2154 106 41 0 TRUE 1.23
colorectal cancer KRAS_G12D RECQL4 291 81 Tumor Type:overall 0.18 -1.14 1.28 1504.74 1.00 1871 277 67 14 TRUE 0.11
non-small cell lung cancer KRAS_G12D RECQL4 151 64 Tumor Type:overall -5.14 -12.13 -0.56 105.24 1.03 3468 151 64 0 TRUE 1.19
colorectal cancer KRAS_G12D MED12 111 28 Metastasis -0.68 -1.82 0.33 1493.67 1.00 747 109 26 2 TRUE 0.70
colorectal cancer KRAS_G12D MED12 181 80 Primary -0.58 -1.37 0.15 1443.84 1.00 1096 174 73 7 TRUE 0.84
non-small cell lung cancer KRAS_G12D MED12 45 57 Metastasis -1.21 -4.22 0.14 919.45 1.00 1284 45 57 0 TRUE 0.52
non-small cell lung cancer KRAS_G12D MED12 106 119 Primary -0.67 -1.89 0.32 527.33 1.00 2087 102 115 4 TRUE 0.61
uterine cancer KRAS_G12D MED12 18 38 Metastasis -1.73 -4.29 -0.09 1304.40 1.00 328 18 38 0 TRUE 0.94
uterine cancer KRAS_G12D MED12 30 102 Primary -1.42 -3.32 -0.07 1208.33 1.00 569 28 100 2 TRUE 1.09
colorectal cancer KRAS_G12D MED12 292 108 Tumor Type:overall -0.64 -1.97 0.42 1542.39 1.00 1843 283 99 9 TRUE 0.55
non-small cell lung cancer KRAS_G12D MED12 151 176 Tumor Type:overall -0.92 -2.81 0.33 887.99 1.00 3371 147 172 4 TRUE 0.55
uterine cancer KRAS_G12D MED12 48 140 Tumor Type:overall -1.55 -3.71 0.07 1362.38 1.00 897 46 138 2 TRUE 0.99
colorectal cancer KRAS_G12D ERCC5 111 14 Metastasis -0.59 -2.03 0.73 1506.86 1.00 756 109 12 2 TRUE 0.41
colorectal cancer KRAS_G12D ERCC5 180 44 Primary -1.00 -2.34 0.06 1361.27 1.00 1122 178 42 2 TRUE 1.01
non-small cell lung cancer KRAS_G12D ERCC5 45 30 Metastasis -0.40 -2.05 1.32 66.98 1.04 1310 43 28 2 TRUE 0.19
non-small cell lung cancer KRAS_G12D ERCC5 106 43 Primary -1.19 -4.76 0.47 1108.21 1.00 2154 106 43 0 TRUE 0.44
uterine cancer KRAS_G12D ERCC5 20 15 Metastasis 1.08 -0.08 2.16 905.01 1.00 348 17 12 3 TRUE 1.23
uterine cancer KRAS_G12D ERCC5 31 37 Primary 0.90 -0.22 1.79 754.51 1.00 619 28 34 3 TRUE 1.10
colorectal cancer KRAS_G12D ERCC5 291 58 Tumor Type:overall -0.78 -2.36 0.70 1377.51 1.00 1878 287 54 4 TRUE 0.52
non-small cell lung cancer KRAS_G12D ERCC5 151 73 Tumor Type:overall -0.76 -3.14 1.08 973.68 1.01 3464 149 71 2 TRUE 0.35
uterine cancer KRAS_G12D ERCC5 51 52 Tumor Type:overall 0.97 -0.32 2.10 935.33 1.00 967 45 46 6 TRUE 0.98
colorectal cancer KRAS_G12D PIK3CD 111 24 Metastasis -0.69 -1.99 0.21 714.14 1.00 747 110 23 1 FALSE 0.67
colorectal cancer KRAS_G12D PIK3CD 181 45 Primary -0.52 -1.49 0.30 723.70 1.00 1122 176 40 5 FALSE 0.59
colorectal cancer KRAS_G12D PIK3CD 292 69 Tumor Type:overall -0.60 -1.75 0.34 757.28 1.00 1869 286 63 6 FALSE 0.56
colorectal cancer KRAS_G12D BRCA1 111 17 Metastasis -1.61 -5.82 0.10 1152.79 1.00 750 111 17 0 TRUE 0.54
colorectal cancer KRAS_G12D BRCA1 180 62 Primary -0.20 -1.03 0.54 1480.81 1.00 1121 172 54 8 TRUE 0.21
non-small cell lung cancer KRAS_G12D BRCA1 45 41 Metastasis -0.04 -1.38 1.20 1395.66 1.00 1299 43 39 2 TRUE 0.02
non-small cell lung cancer KRAS_G12D BRCA1 106 56 Primary -0.17 -1.48 0.82 1422.42 1.00 2142 104 54 2 TRUE 0.11
colorectal cancer KRAS_G12D BRCA1 291 79 Tumor Type:overall -0.86 -3.44 0.73 1384.36 1.00 1871 283 71 8 TRUE 0.37
non-small cell lung cancer KRAS_G12D BRCA1 151 97 Tumor Type:overall -0.08 -1.57 1.16 1484.85 1.00 3441 147 93 4 TRUE 0.05
colorectal cancer KRAS_G12D RBM10 111 22 Metastasis 0.00 -0.94 0.78 897.93 1.00 748 108 19 3 FALSE 0.00
colorectal cancer KRAS_G12D RBM10 180 50 Primary 0.02 -0.72 0.73 761.85 1.00 1124 173 43 7 FALSE 0.02
non-small cell lung cancer KRAS_G12D RBM10 46 122 Metastasis 0.66 -0.06 1.25 1543.83 1.00 1227 39 115 7 FALSE 1.32
non-small cell lung cancer KRAS_G12D RBM10 109 261 Primary 0.77 0.34 1.17 1425.99 1.00 1965 86 238 23 FALSE 3.33
uterine cancer KRAS_G12D RBM10 30 46 Primary -0.22 -2.06 1.06 1052.07 1.00 611 28 44 2 FALSE 0.11
colorectal cancer KRAS_G12D RBM10 291 72 Tumor Type:overall 0.01 -1.00 0.92 1059.06 1.00 1872 281 62 10 FALSE 0.01
non-small cell lung cancer KRAS_G12D RBM10 155 383 Tumor Type:overall 0.71 -0.07 1.44 1464.56 1.00 3192 125 353 30 FALSE 0.97
uterine cancer KRAS_G12D RBM10 30 46 Tumor Type:overall -0.21 -4.65 4.58 1417.08 1.00 611 28 44 2 FALSE 0.04
colorectal cancer KRAS_G12D TSC1 111 16 Metastasis -0.11 -1.19 0.92 1336.22 1.00 756 109 14 2 TRUE 0.07
colorectal cancer KRAS_G12D TSC1 180 51 Primary -0.01 -0.83 0.68 1266.06 1.00 1125 173 44 7 TRUE 0.01
non-small cell lung cancer KRAS_G12D TSC1 45 25 Metastasis -4.98 -11.84 -0.36 524.75 1.01 1312 45 25 0 TRUE 1.02
non-small cell lung cancer KRAS_G12D TSC1 106 32 Primary -5.08 -11.81 -0.48 528.50 1.01 2161 106 32 0 TRUE 1.06
uterine cancer KRAS_G12D TSC1 20 16 Metastasis 1.78 0.53 3.06 1448.30 1.00 351 15 11 5 TRUE 2.20
uterine cancer KRAS_G12D TSC1 30 46 Primary 0.40 -1.18 1.52 1329.55 1.00 610 28 44 2 TRUE 0.25
colorectal cancer KRAS_G12D TSC1 291 67 Tumor Type:overall -0.06 -1.35 1.03 1511.38 1.00 1881 282 58 9 TRUE 0.04
non-small cell lung cancer KRAS_G12D TSC1 151 57 Tumor Type:overall -4.98 -11.41 -0.43 522.67 1.01 3473 151 57 0 TRUE 1.04
uterine cancer KRAS_G12D TSC1 50 62 Tumor Type:overall 1.06 -0.91 3.07 1487.09 1.00 961 43 55 7 TRUE 0.56
colorectal cancer KRAS_G12D FLCN 111 18 Metastasis -0.82 -2.18 0.26 1208.16 1.00 753 110 17 1 TRUE 0.71
colorectal cancer KRAS_G12D FLCN 181 36 Primary -0.75 -1.96 0.27 1049.99 1.00 1129 178 33 3 TRUE 0.74
colorectal cancer KRAS_G12D FLCN 292 54 Tumor Type:overall -0.77 -2.05 0.37 1123.03 1.00 1882 288 50 4 TRUE 0.68
cancer of unknown primary KRAS_G12D NF1 42 54 Metastasis -1.70 -4.36 0.12 1333.30 1.00 605 41 53 1 TRUE 0.84
colorectal cancer KRAS_G12D NF1 111 37 Metastasis -0.84 -1.99 0.01 1489.17 1.00 738 109 35 2 TRUE 0.97
colorectal cancer KRAS_G12D NF1 181 105 Primary -0.62 -1.33 0.01 1448.57 1.00 1093 172 96 9 TRUE 1.10
non-small cell lung cancer KRAS_G12D NF1 45 125 Metastasis -0.55 -1.52 0.47 509.50 1.00 1234 41 121 4 TRUE 0.55
non-small cell lung cancer KRAS_G12D NF1 106 190 Primary -0.87 -1.81 -0.04 1297.83 1.00 2032 103 187 3 TRUE 1.21
uterine cancer KRAS_G12D NF1 18 30 Metastasis 0.12 -1.39 1.58 1338.56 1.00 341 15 27 3 TRUE 0.06
uterine cancer KRAS_G12D NF1 30 93 Primary -0.94 -2.93 0.32 1341.69 1.00 589 29 92 1 TRUE 0.61
cancer of unknown primary KRAS_G12D NF1 42 54 Tumor Type:overall -1.38 -5.84 3.60 1417.23 1.00 605 41 53 1 TRUE 0.27
colorectal cancer KRAS_G12D NF1 292 142 Tumor Type:overall -0.69 -1.77 0.44 1309.49 1.00 1831 281 131 11 TRUE 0.62
non-small cell lung cancer KRAS_G12D NF1 151 315 Tumor Type:overall -0.71 -1.86 0.34 1108.12 1.00 3266 144 308 7 TRUE 0.65
uterine cancer KRAS_G12D NF1 48 123 Tumor Type:overall -0.39 -2.37 1.52 1611.14 1.00 930 44 119 4 TRUE 0.16
colorectal cancer KRAS_G12D FLT1 111 20 Metastasis -0.10 -1.08 0.84 1083.99 1.01 753 108 17 3 FALSE 0.07
colorectal cancer KRAS_G12D FLT1 182 62 Primary -0.20 -0.96 0.50 942.88 1.01 1115 175 55 7 FALSE 0.23
non-small cell lung cancer KRAS_G12D FLT1 45 52 Metastasis -1.54 -4.26 0.01 883.52 1.00 1290 45 52 0 FALSE 0.82
non-small cell lung cancer KRAS_G12D FLT1 106 84 Primary -1.28 -3.17 0.11 594.50 1.00 2117 104 82 2 FALSE 0.94
uterine cancer KRAS_G12D FLT1 18 13 Metastasis -1.67 -4.86 0.51 1181.66 1.00 348 18 13 0 FALSE 0.59
uterine cancer KRAS_G12D FLT1 30 43 Primary -1.40 -3.95 0.45 1090.13 1.00 613 29 42 1 FALSE 0.64
colorectal cancer KRAS_G12D FLT1 293 82 Tumor Type:overall -0.14 -1.38 1.08 1164.70 1.00 1868 283 72 10 FALSE 0.09
non-small cell lung cancer KRAS_G12D FLT1 151 136 Tumor Type:overall -1.39 -3.52 0.19 829.14 1.00 3407 149 134 2 FALSE 0.85
uterine cancer KRAS_G12D FLT1 48 56 Tumor Type:overall -1.51 -4.56 0.61 1114.02 1.00 961 47 55 1 FALSE 0.59
colorectal cancer KRAS_G12D RPTOR 111 19 Metastasis -0.60 -2.10 0.41 1285.15 1.00 753 110 18 1 FALSE 0.47
colorectal cancer KRAS_G12D RPTOR 181 51 Primary -0.34 -1.18 0.45 1212.10 1.00 1117 175 45 6 FALSE 0.37
non-small cell lung cancer KRAS_G12D RPTOR 45 27 Metastasis -4.90 -11.46 -0.62 657.24 1.00 1311 45 27 0 FALSE 1.05
non-small cell lung cancer KRAS_G12D RPTOR 106 38 Primary -4.87 -11.62 -0.71 687.20 1.00 2155 106 38 0 FALSE 1.06
colorectal cancer KRAS_G12D RPTOR 292 70 Tumor Type:overall -0.47 -1.93 0.79 1471.56 1.00 1870 285 63 7 FALSE 0.32
non-small cell lung cancer KRAS_G12D RPTOR 151 65 Tumor Type:overall -4.82 -11.24 -0.56 674.84 1.00 3466 151 65 0 FALSE 1.06
colorectal cancer KRAS_G12D RASA1 111 17 Metastasis -0.23 -1.41 1.00 1392.99 1.00 755 108 14 3 FALSE 0.15
colorectal cancer KRAS_G12D RASA1 180 56 Primary -0.84 -2.08 0.08 1466.59 1.00 1122 177 53 3 FALSE 0.94
non-small cell lung cancer KRAS_G12D RASA1 45 38 Metastasis 0.14 -1.48 1.62 680.25 1.00 1303 42 35 3 FALSE 0.07
non-small cell lung cancer KRAS_G12D RASA1 106 60 Primary -1.54 -6.34 0.26 1041.08 1.00 2133 106 60 0 FALSE 0.41
uterine cancer KRAS_G12D RASA1 18 21 Metastasis -5.43 -12.65 -0.94 766.85 1.00 341 18 21 0 FALSE 1.13
uterine cancer KRAS_G12D RASA1 30 84 Primary -5.50 -12.55 -1.27 633.23 1.00 595 30 84 0 FALSE 1.21
colorectal cancer KRAS_G12D RASA1 291 73 Tumor Type:overall -0.52 -2.15 1.09 1527.47 1.00 1877 285 67 6 FALSE 0.29
non-small cell lung cancer KRAS_G12D RASA1 151 98 Tumor Type:overall -0.68 -3.64 1.25 1276.59 1.00 3436 148 95 3 FALSE 0.23
uterine cancer KRAS_G12D RASA1 48 105 Tumor Type:overall -5.34 -11.97 -0.91 738.43 1.00 936 48 105 0 FALSE 1.17
colorectal cancer KRAS_G12D EPHA5 111 43 Metastasis -0.72 -1.90 0.10 1353.29 1.00 729 109 41 2 FALSE 0.85
colorectal cancer KRAS_G12D EPHA5 181 101 Primary -0.40 -1.03 0.21 1479.95 1.00 1092 170 90 11 FALSE 0.67
non-small cell lung cancer KRAS_G12D EPHA5 45 108 Metastasis -0.85 -2.23 0.12 1107.70 1.00 1239 44 107 1 FALSE 0.78
non-small cell lung cancer KRAS_G12D EPHA5 106 152 Primary -0.60 -1.60 0.22 1106.68 1.00 2060 101 147 5 FALSE 0.72
uterine cancer KRAS_G12D EPHA5 20 24 Metastasis 0.93 -0.69 2.28 738.21 1.00 347 16 20 4 FALSE 0.65
uterine cancer KRAS_G12D EPHA5 30 74 Primary -2.26 -7.49 0.14 1131.29 1.00 592 30 74 0 FALSE 0.52
colorectal cancer KRAS_G12D EPHA5 292 144 Tumor Type:overall -0.55 -1.63 0.35 1467.41 1.00 1821 279 131 13 FALSE 0.49
non-small cell lung cancer KRAS_G12D EPHA5 151 260 Tumor Type:overall -0.73 -2.01 0.30 1274.28 1.00 3299 145 254 6 FALSE 0.65
uterine cancer KRAS_G12D EPHA5 50 98 Tumor Type:overall -0.52 -4.12 2.35 1536.76 1.00 939 46 94 4 FALSE 0.13
colorectal cancer KRAS_G12D AR 111 21 Metastasis -1.09 -2.82 0.25 1521.87 1.00 747 110 20 1 TRUE 0.79
colorectal cancer KRAS_G12D AR 180 95 Primary -0.77 -1.56 -0.06 1444.87 1.00 1085 173 88 7 TRUE 1.33
non-small cell lung cancer KRAS_G12D AR 45 39 Metastasis -0.13 -1.41 1.13 1463.55 1.00 1303 43 37 2 TRUE 0.08
non-small cell lung cancer KRAS_G12D AR 106 71 Primary -0.34 -1.58 0.65 1494.95 1.00 2129 104 69 2 TRUE 0.26
uterine cancer KRAS_G12D AR 18 17 Metastasis -0.18 -1.94 1.21 543.28 1.00 345 17 16 1 TRUE 0.09
uterine cancer KRAS_G12D AR 30 48 Primary -0.21 -1.77 1.04 475.39 1.00 608 28 46 2 TRUE 0.11
colorectal cancer KRAS_G12D AR 291 116 Tumor Type:overall -0.92 -2.67 0.52 1420.94 1.00 1832 283 108 8 TRUE 0.56
non-small cell lung cancer KRAS_G12D AR 151 110 Tumor Type:overall -0.23 -1.63 0.99 1439.80 1.00 3432 147 106 4 TRUE 0.13
uterine cancer KRAS_G12D AR 48 65 Tumor Type:overall -0.18 -1.99 1.27 642.31 1.00 953 45 62 3 TRUE 0.08
colorectal cancer KRAS_G12D GNAS 128 20 Metastasis 0.39 -0.52 1.28 252.79 1.01 810 123 15 5 TRUE 0.39
colorectal cancer KRAS_G12D GNAS 204 55 Primary 0.13 -0.67 1.09 74.80 1.04 1250 197 48 7 TRUE 0.12
pancreatic cancer KRAS_G12D GNAS 208 15 Metastasis -0.63 -1.66 0.16 1499.88 1.00 384 205 12 3 TRUE 0.77
pancreatic cancer KRAS_G12D GNAS 286 47 Primary -0.35 -0.99 0.28 1223.89 1.00 604 274 35 12 TRUE 0.54
colorectal cancer KRAS_G12D GNAS 332 75 Tumor Type:overall 0.28 -0.84 1.32 253.68 1.01 2060 320 63 12 TRUE 0.19
pancreatic cancer KRAS_G12D GNAS 494 62 Tumor Type:overall -0.49 -1.71 0.58 1366.30 1.00 988 479 47 15 TRUE 0.40
colorectal cancer KRAS_G12D ASXL2 111 15 Metastasis -1.29 -3.14 0.28 1176.44 1.00 755 110 14 1 FALSE 0.88
colorectal cancer KRAS_G12D ASXL2 180 56 Primary -1.50 -2.93 -0.37 1195.52 1.00 1125 178 54 2 FALSE 1.55
non-small cell lung cancer KRAS_G12D ASXL2 45 29 Metastasis -1.66 -4.99 0.35 1364.73 1.00 1309 45 29 0 FALSE 0.63
non-small cell lung cancer KRAS_G12D ASXL2 106 34 Primary -1.30 -3.93 0.50 1295.49 1.00 2161 105 33 1 FALSE 0.59
colorectal cancer KRAS_G12D ASXL2 291 71 Tumor Type:overall -1.37 -3.24 0.35 932.18 1.01 1880 288 68 3 FALSE 0.83
non-small cell lung cancer KRAS_G12D ASXL2 151 63 Tumor Type:overall -1.44 -4.42 0.59 1375.64 1.00 3470 150 62 1 FALSE 0.60
colorectal cancer KRAS_G12D SF3B1 111 21 Metastasis -1.11 -2.33 -0.02 649.90 1.00 756 110 20 1 TRUE 1.13
colorectal cancer KRAS_G12D SF3B1 180 49 Primary -1.07 -2.24 -0.07 478.39 1.01 1122 177 46 3 TRUE 1.23
non-small cell lung cancer KRAS_G12D SF3B1 45 33 Metastasis -0.86 -2.78 0.70 140.18 1.01 1305 44 32 1 TRUE 0.47
non-small cell lung cancer KRAS_G12D SF3B1 106 54 Primary -0.96 -2.72 0.40 150.53 1.01 2144 105 53 1 TRUE 0.59
colorectal cancer KRAS_G12D SF3B1 291 70 Tumor Type:overall -1.08 -2.34 0.01 417.82 1.01 1878 287 66 4 TRUE 1.10
non-small cell lung cancer KRAS_G12D SF3B1 151 87 Tumor Type:overall -0.91 -3.02 0.61 154.26 1.01 3449 149 85 2 TRUE 0.49
colorectal cancer KRAS_G12D MLH1 128 12 Metastasis -1.36 -4.54 0.28 1097.17 1.00 813 128 12 0 TRUE 0.51
colorectal cancer KRAS_G12D MLH1 204 44 Primary -0.44 -1.49 0.46 1213.41 1.00 1263 199 39 5 TRUE 0.42
colorectal cancer KRAS_G12D MLH1 332 56 Tumor Type:overall -0.82 -3.00 0.86 1237.10 1.00 2076 327 51 5 TRUE 0.38
colorectal cancer KRAS_G12D ROS1 111 33 Metastasis -1.01 -2.08 -0.08 1386.32 1.00 742 109 31 2 TRUE 1.29
colorectal cancer KRAS_G12D ROS1 180 70 Primary -1.02 -2.01 -0.20 1343.99 1.00 1111 176 66 4 TRUE 1.58
non-small cell lung cancer KRAS_G12D ROS1 45 35 Metastasis -2.18 -5.47 -0.21 1256.00 1.00 1302 45 35 0 TRUE 0.94
non-small cell lung cancer KRAS_G12D ROS1 106 76 Primary -1.99 -4.56 -0.21 1023.97 1.00 2122 105 75 1 TRUE 1.08
uterine cancer KRAS_G12D ROS1 19 19 Metastasis 0.80 -1.01 2.29 1329.97 1.00 347 16 16 3 TRUE 0.46
uterine cancer KRAS_G12D ROS1 30 81 Primary -2.54 -7.98 -0.02 1120.04 1.00 609 30 81 0 TRUE 0.61
colorectal cancer KRAS_G12D ROS1 291 103 Tumor Type:overall -1.02 -2.10 -0.01 1301.07 1.00 1853 285 97 6 TRUE 1.24
non-small cell lung cancer KRAS_G12D ROS1 151 111 Tumor Type:overall -2.06 -5.00 -0.08 1068.01 1.00 3424 150 110 1 TRUE 1.00
uterine cancer KRAS_G12D ROS1 49 100 Tumor Type:overall -0.78 -4.42 2.05 1454.39 1.00 956 46 97 3 TRUE 0.20
colorectal cancer KRAS_G12D PIK3R2 180 42 Primary -0.22 -1.25 0.67 1417.09 1.00 1127 175 37 5 FALSE 0.19
colorectal cancer KRAS_G12D PIK3R2 180 42 Tumor Type:overall -0.13 -4.36 4.32 1364.17 1.00 1127 175 37 5 FALSE 0.02
colorectal cancer KRAS_G12D FLT3 128 13 Metastasis -0.81 -2.32 0.45 923.94 1.00 816 127 12 1 TRUE 0.60
colorectal cancer KRAS_G12D FLT3 204 39 Primary -0.77 -1.97 0.20 583.07 1.00 1263 201 36 3 TRUE 0.76
non-small cell lung cancer KRAS_G12D FLT3 48 41 Metastasis -0.12 -1.66 1.17 689.74 1.00 1348 46 39 2 TRUE 0.06
non-small cell lung cancer KRAS_G12D FLT3 109 40 Primary -0.43 -2.12 0.86 854.39 1.00 2226 108 39 1 TRUE 0.24
uterine cancer KRAS_G12D FLT3 18 19 Metastasis -1.29 -4.17 0.64 1032.66 1.00 368 17 18 1 TRUE 0.53
uterine cancer KRAS_G12D FLT3 32 42 Primary -1.64 -4.76 0.30 765.53 1.00 707 32 42 0 TRUE 0.65
colorectal cancer KRAS_G12D FLT3 332 52 Tumor Type:overall -0.79 -2.29 0.44 623.75 1.01 2079 328 48 4 TRUE 0.59
non-small cell lung cancer KRAS_G12D FLT3 157 81 Tumor Type:overall -0.26 -2.00 1.30 796.41 1.00 3574 154 78 3 TRUE 0.12
uterine cancer KRAS_G12D FLT3 50 61 Tumor Type:overall -1.44 -4.16 0.57 984.55 1.00 1075 49 60 1 TRUE 0.59
colorectal cancer KRAS_G12D MSH2 111 22 Metastasis -0.67 -2.06 0.33 1207.13 1.00 751 110 21 1 TRUE 0.56
colorectal cancer KRAS_G12D MSH2 180 61 Primary -0.35 -1.17 0.37 1250.19 1.00 1123 173 54 7 TRUE 0.41
non-small cell lung cancer KRAS_G12D MSH2 45 24 Metastasis -0.39 -2.35 1.22 1329.87 1.00 1317 44 23 1 TRUE 0.17
non-small cell lung cancer KRAS_G12D MSH2 106 32 Primary -0.47 -2.40 0.95 1326.24 1.00 2162 105 31 1 TRUE 0.23
uterine cancer KRAS_G12D MSH2 19 15 Metastasis 0.44 -1.01 1.88 1339.82 1.00 348 17 13 2 TRUE 0.26
uterine cancer KRAS_G12D MSH2 30 51 Primary 0.07 -1.23 1.14 1032.48 1.00 610 28 49 2 TRUE 0.04
colorectal cancer KRAS_G12D MSH2 291 83 Tumor Type:overall -0.53 -1.95 0.57 1391.69 1.00 1874 283 75 8 TRUE 0.39
non-small cell lung cancer KRAS_G12D MSH2 151 56 Tumor Type:overall -0.42 -2.33 1.16 1353.63 1.00 3479 149 54 2 TRUE 0.19
uterine cancer KRAS_G12D MSH2 49 66 Tumor Type:overall 0.24 -1.34 1.64 1530.49 1.00 958 45 62 4 TRUE 0.12
non-small cell lung cancer KRAS_G12D DIS3 45 27 Metastasis -0.79 -3.31 0.77 1243.83 1.00 1310 45 27 0 FALSE 0.31
non-small cell lung cancer KRAS_G12D DIS3 106 38 Primary -0.44 -2.30 0.89 1324.63 1.00 2158 104 36 2 FALSE 0.24
non-small cell lung cancer KRAS_G12D DIS3 151 65 Tumor Type:overall -0.60 -2.82 0.94 1311.72 1.00 3468 149 63 2 FALSE 0.28
colorectal cancer KRAS_G12D AXL 111 22 Metastasis -1.62 -5.29 -0.08 1176.10 1.00 749 111 22 0 FALSE 0.67
colorectal cancer KRAS_G12D AXL 180 66 Primary -0.54 -1.50 0.24 389.43 1.01 1112 173 59 7 FALSE 0.65
colorectal cancer KRAS_G12D AXL 291 88 Tumor Type:overall -1.05 -3.23 0.39 1369.64 1.00 1861 284 81 7 FALSE 0.58
pancreatic cancer KRAS_G12D DAXX 201 26 Metastasis -2.63 -4.44 -1.23 1331.22 1.00 356 199 24 2 TRUE 3.06
pancreatic cancer KRAS_G12D DAXX 280 27 Primary -3.20 -6.07 -1.55 1400.71 1.00 589 280 27 0 TRUE 1.97
pancreatic cancer KRAS_G12D DAXX 481 53 Tumor Type:overall -2.87 -5.08 -1.23 1377.25 1.00 945 479 51 2 TRUE 2.38
colorectal cancer KRAS_G12D PIK3CG 113 34 Metastasis -0.23 -1.13 0.42 770.36 1.01 737 110 31 3 FALSE 0.25
colorectal cancer KRAS_G12D PIK3CG 180 73 Primary -0.10 -0.79 0.50 748.48 1.00 1109 170 63 10 FALSE 0.12
non-small cell lung cancer KRAS_G12D PIK3CG 45 72 Metastasis -1.60 -3.50 -0.10 552.25 1.00 1273 44 71 1 FALSE 1.09
non-small cell lung cancer KRAS_G12D PIK3CG 106 108 Primary -1.71 -3.53 -0.34 627.11 1.00 2097 105 107 1 FALSE 1.29
uterine cancer KRAS_G12D PIK3CG 19 16 Metastasis 0.26 -1.33 1.64 896.61 1.01 349 17 14 2 FALSE 0.14
uterine cancer KRAS_G12D PIK3CG 30 35 Primary -0.01 -1.81 1.16 389.87 1.01 616 29 34 1 FALSE 0.01
colorectal cancer KRAS_G12D PIK3CG 293 107 Tumor Type:overall -0.17 -1.07 0.62 942.96 1.00 1846 280 94 13 FALSE 0.16
non-small cell lung cancer KRAS_G12D PIK3CG 151 180 Tumor Type:overall -1.64 -3.53 -0.16 676.46 1.00 3370 149 178 2 FALSE 1.15
uterine cancer KRAS_G12D PIK3CG 49 51 Tumor Type:overall 0.14 -1.61 1.48 675.30 1.00 965 46 48 3 FALSE 0.06
colorectal cancer KRAS_G12D MAP2K4 111 24 Metastasis -1.29 -3.47 -0.05 1138.97 1.00 744 111 24 0 TRUE 0.83
colorectal cancer KRAS_G12D MAP2K4 181 39 Primary -0.90 -1.92 0.09 162.14 1.02 1126 177 35 4 TRUE 0.98
colorectal cancer KRAS_G12D MAP2K4 292 63 Tumor Type:overall -1.09 -2.51 0.10 974.60 1.00 1870 288 59 4 TRUE 0.93
colorectal cancer KRAS_G12D EGFR 128 16 Metastasis -1.32 -2.97 0.12 1340.94 1.00 812 127 15 1 TRUE 1.05
colorectal cancer KRAS_G12D EGFR 204 50 Primary -1.38 -2.83 -0.26 1280.44 1.00 1250 202 48 2 TRUE 1.50
non-small cell lung cancer KRAS_G12D EGFR 47 432 Metastasis -2.97 -4.32 -1.68 114.34 1.03 1045 45 430 2 TRUE 4.56
non-small cell lung cancer KRAS_G12D EGFR 109 610 Primary -3.25 -4.72 -2.09 178.24 1.02 1751 108 609 1 TRUE 5.73
colorectal cancer KRAS_G12D EGFR 332 66 Tumor Type:overall -1.33 -2.96 0.18 1356.86 1.00 2062 329 63 3 TRUE 1.06
non-small cell lung cancer KRAS_G12D EGFR 156 1042 Tumor Type:overall -3.10 -4.49 -1.75 126.87 1.03 2796 153 1039 3 TRUE 4.77
colorectal cancer KRAS_G12D ARID1B 111 35 Metastasis -1.33 -2.75 -0.27 1396.71 1.00 738 110 34 1 TRUE 1.35
colorectal cancer KRAS_G12D ARID1B 181 105 Primary -0.96 -1.75 -0.22 1557.23 1.00 1079 174 98 7 TRUE 1.79
non-small cell lung cancer KRAS_G12D ARID1B 45 55 Metastasis -0.43 -2.03 0.87 1383.27 1.00 1288 43 53 2 TRUE 0.26
non-small cell lung cancer KRAS_G12D ARID1B 106 56 Primary -0.77 -2.50 0.48 1249.83 1.00 2139 105 55 1 TRUE 0.50
uterine cancer KRAS_G12D ARID1B 18 35 Metastasis 0.90 0.06 1.88 382.95 1.01 334 13 30 5 TRUE 1.28
uterine cancer KRAS_G12D ARID1B 31 79 Primary 0.65 -0.21 1.41 1086.75 1.00 589 26 74 5 TRUE 0.95
colorectal cancer KRAS_G12D ARID1B 292 140 Tumor Type:overall -1.14 -2.57 0.00 1384.07 1.00 1817 284 132 8 TRUE 1.03
non-small cell lung cancer KRAS_G12D ARID1B 151 111 Tumor Type:overall -0.61 -2.45 0.91 1352.32 1.00 3427 148 108 3 TRUE 0.32
uterine cancer KRAS_G12D ARID1B 49 114 Tumor Type:overall 0.77 -0.24 1.81 1377.06 1.01 923 39 104 10 TRUE 0.87
non-small cell lung cancer KRAS_G12D INSR 45 22 Metastasis -1.46 -4.93 0.57 1229.07 1.00 1315 45 22 0 FALSE 0.52
non-small cell lung cancer KRAS_G12D INSR 106 33 Primary -1.18 -4.00 0.65 1283.00 1.00 2163 105 32 1 FALSE 0.51
non-small cell lung cancer KRAS_G12D INSR 151 55 Tumor Type:overall -1.33 -4.43 0.60 1208.13 1.00 3478 150 54 1 FALSE 0.51
non-small cell lung cancer KRAS_G12D NKX2-1 45 18 Metastasis 0.88 -0.78 1.96 1503.47 1.00 1322 44 17 1 TRUE 0.71
non-small cell lung cancer KRAS_G12D NKX2-1 108 57 Primary 1.28 0.50 1.99 1194.55 1.00 2150 99 48 9 TRUE 3.20
non-small cell lung cancer KRAS_G12D NKX2-1 153 75 Tumor Type:overall 1.06 -0.39 2.29 1437.98 1.00 3472 143 65 10 TRUE 0.87
colorectal cancer KRAS_G12D ARID5B 111 15 Metastasis -1.43 -5.68 0.31 1380.88 1.00 753 111 15 0 FALSE 0.42
colorectal cancer KRAS_G12D ARID5B 182 53 Primary -0.06 -1.04 0.74 949.41 1.00 1126 174 45 8 FALSE 0.05
uterine cancer KRAS_G12D ARID5B 20 19 Metastasis 1.58 0.30 2.87 1310.69 1.00 347 15 14 5 FALSE 1.77
uterine cancer KRAS_G12D ARID5B 30 62 Primary 0.02 -1.53 1.17 1280.39 1.00 596 28 60 2 FALSE 0.01
colorectal cancer KRAS_G12D ARID5B 293 68 Tumor Type:overall -0.71 -3.49 1.05 1417.48 1.00 1879 285 60 8 FALSE 0.27
uterine cancer KRAS_G12D ARID5B 50 81 Tumor Type:overall 0.82 -1.09 2.65 1566.85 1.00 943 43 74 7 FALSE 0.40
non-small cell lung cancer KRAS_G12D WT1 46 28 Metastasis 1.54 0.28 2.61 1181.23 1.00 1314 41 23 5 TRUE 2.00
non-small cell lung cancer KRAS_G12D WT1 106 42 Primary -1.75 -6.84 0.76 1286.16 1.00 2153 106 42 0 TRUE 0.40
non-small cell lung cancer KRAS_G12D WT1 152 70 Tumor Type:overall -0.06 -3.72 2.60 1313.56 1.00 3467 147 65 5 TRUE 0.01
non-small cell lung cancer KRAS_G12D MET 47 56 Metastasis -0.79 -2.30 0.66 1441.32 1.00 1335 45 54 2 TRUE 0.55
non-small cell lung cancer KRAS_G12D MET 109 109 Primary -1.20 -2.75 0.05 1306.05 1.00 2167 108 108 1 TRUE 1.01
uterine cancer KRAS_G12D MET 19 19 Metastasis 0.64 -0.69 2.00 1013.65 1.00 367 16 16 3 TRUE 0.47
uterine cancer KRAS_G12D MET 32 40 Primary 0.15 -1.44 1.29 1271.10 1.00 712 31 39 1 TRUE 0.08
non-small cell lung cancer KRAS_G12D MET 156 165 Tumor Type:overall -0.98 -2.68 0.48 1293.92 1.00 3502 153 162 3 TRUE 0.63
uterine cancer KRAS_G12D MET 51 59 Tumor Type:overall 0.41 -1.07 1.86 1319.18 1.00 1079 47 55 4 TRUE 0.24
non-small cell lung cancer KRAS_G12D PMS1 45 23 Metastasis -0.72 -3.42 1.06 470.27 1.00 1315 45 23 0 TRUE 0.25
non-small cell lung cancer KRAS_G12D PMS1 106 29 Primary -0.28 -2.23 1.15 159.02 1.02 2165 104 27 2 TRUE 0.12
non-small cell lung cancer KRAS_G12D PMS1 151 52 Tumor Type:overall -0.49 -2.94 1.21 305.38 1.01 3480 149 50 2 TRUE 0.19
pancreatic cancer KRAS_G12D MEN1 201 33 Metastasis -4.03 -6.74 -2.30 657.40 1.00 346 201 33 0 TRUE 3.25
pancreatic cancer KRAS_G12D MEN1 280 44 Primary -3.88 -6.56 -2.26 669.42 1.00 571 279 43 1 TRUE 3.56
pancreatic cancer KRAS_G12D MEN1 481 77 Tumor Type:overall -3.94 -6.57 -2.23 701.04 1.00 917 480 76 1 TRUE 3.33
non-small cell lung cancer KRAS_G12D PIK3C3 45 26 Metastasis -1.89 -5.29 0.27 1335.57 1.00 1311 45 26 0 FALSE 0.72
non-small cell lung cancer KRAS_G12D PIK3C3 106 50 Primary -1.64 -4.58 0.23 1349.35 1.00 2145 105 49 1 FALSE 0.73
non-small cell lung cancer KRAS_G12D PIK3C3 151 76 Tumor Type:overall -1.74 -4.68 0.42 1198.51 1.00 3456 150 75 1 FALSE 0.72
colorectal cancer KRAS_G12D BRAF 128 79 Metastasis -2.18 -3.35 -1.18 1239.54 1.00 751 126 77 2 TRUE 4.19
colorectal cancer KRAS_G12D BRAF 205 174 Primary -2.28 -3.39 -1.42 1222.81 1.00 1131 202 171 3 TRUE 5.28
non-small cell lung cancer KRAS_G12D BRAF 47 72 Metastasis -0.78 -2.19 0.16 52.68 1.05 1314 46 71 1 TRUE 0.65
non-small cell lung cancer KRAS_G12D BRAF 109 121 Primary -0.74 -1.97 0.10 48.38 1.05 2149 106 118 3 TRUE 0.72
colorectal cancer KRAS_G12D BRAF 333 253 Tumor Type:overall -2.23 -3.44 -1.19 1329.56 1.00 1882 328 248 5 TRUE 3.80
non-small cell lung cancer KRAS_G12D BRAF 156 193 Tumor Type:overall -0.76 -2.23 0.18 58.49 1.05 3463 152 189 4 TRUE 0.62
colorectal cancer KRAS_G12D B2M 111 15 Metastasis -2.08 -6.55 0.12 1188.33 1.00 757 111 15 0 FALSE 0.64
colorectal cancer KRAS_G12D B2M 187 124 Primary -0.12 -0.72 0.42 1384.52 1.00 1092 171 108 16 FALSE 0.18
colorectal cancer KRAS_G12D B2M 298 139 Tumor Type:overall -1.02 -4.24 1.27 1462.37 1.00 1849 282 123 16 FALSE 0.34
colorectal cancer KRAS_G12D TGFBR1 111 13 Metastasis 0.09 -0.99 1.06 1230.14 1.00 758 109 11 2 FALSE 0.06
colorectal cancer KRAS_G12D TGFBR1 181 38 Primary 0.14 -0.68 0.92 1195.80 1.00 1132 175 32 6 FALSE 0.14
non-small cell lung cancer KRAS_G12D TGFBR1 45 23 Metastasis 0.08 -1.93 1.70 1449.74 1.00 1316 43 21 2 FALSE 0.03
non-small cell lung cancer KRAS_G12D TGFBR1 106 28 Primary -0.85 -4.35 0.89 1018.75 1.00 2164 106 28 0 FALSE 0.27
colorectal cancer KRAS_G12D TGFBR1 292 51 Tumor Type:overall 0.12 -1.11 1.23 1358.78 1.00 1890 284 43 8 FALSE 0.07
non-small cell lung cancer KRAS_G12D TGFBR1 151 51 Tumor Type:overall -0.35 -2.94 1.34 1151.38 1.00 3480 149 49 2 FALSE 0.13
colorectal cancer KRAS_G12D TET2 111 14 Metastasis -0.65 -2.48 0.68 1498.48 1.00 756 110 13 1 TRUE 0.38
colorectal cancer KRAS_G12D TET2 181 77 Primary -0.24 -1.03 0.40 1429.34 1.00 1107 172 68 9 TRUE 0.29
non-small cell lung cancer KRAS_G12D TET2 45 38 Metastasis 0.22 -1.35 1.64 1037.06 1.00 1304 42 35 3 TRUE 0.11
non-small cell lung cancer KRAS_G12D TET2 106 43 Primary -1.26 -5.03 0.50 938.19 1.00 2152 106 43 0 TRUE 0.40
uterine cancer KRAS_G12D TET2 18 25 Metastasis -0.01 -1.50 1.19 875.85 1.01 343 16 23 2 TRUE 0.01
uterine cancer KRAS_G12D TET2 30 41 Primary -0.18 -1.78 0.86 375.32 1.02 611 29 40 1 TRUE 0.10
colorectal cancer KRAS_G12D TET2 292 91 Tumor Type:overall -0.43 -2.25 1.30 1494.92 1.00 1863 282 81 10 TRUE 0.21
non-small cell lung cancer KRAS_G12D TET2 151 81 Tumor Type:overall -0.48 -3.17 1.39 1483.11 1.00 3456 148 78 3 TRUE 0.18
uterine cancer KRAS_G12D TET2 48 66 Tumor Type:overall -0.09 -1.72 1.12 761.52 1.01 954 45 63 3 TRUE 0.05
colorectal cancer KRAS_G12D PDGFRB 180 46 Primary -0.32 -1.36 0.53 1301.44 1.00 1120 175 41 5 TRUE 0.29
non-small cell lung cancer KRAS_G12D PDGFRB 45 37 Metastasis -1.99 -5.05 0.12 1081.41 1.00 1302 45 37 0 TRUE 0.88
non-small cell lung cancer KRAS_G12D PDGFRB 106 55 Primary -1.78 -4.52 0.02 1105.55 1.00 2145 105 54 1 TRUE 0.90
colorectal cancer KRAS_G12D PDGFRB 180 46 Tumor Type:overall -0.14 -4.35 4.71 1387.36 1.00 1120 175 41 5 TRUE 0.02
non-small cell lung cancer KRAS_G12D PDGFRB 151 92 Tumor Type:overall -1.85 -4.82 0.21 937.75 1.00 3447 150 91 1 TRUE 0.84
colorectal cancer KRAS_G12D CARD11 111 29 Metastasis -0.97 -2.71 0.18 1298.64 1.00 742 110 28 1 FALSE 0.70
colorectal cancer KRAS_G12D CARD11 181 99 Primary -0.13 -0.76 0.44 1719.24 1.00 1083 168 86 13 FALSE 0.17
non-small cell lung cancer KRAS_G12D CARD11 45 43 Metastasis 0.05 -1.71 1.52 1094.53 1.00 1298 42 40 3 FALSE 0.02
non-small cell lung cancer KRAS_G12D CARD11 106 87 Primary -2.08 -6.63 -0.06 912.50 1.00 2111 106 87 0 FALSE 0.64
uterine cancer KRAS_G12D CARD11 18 16 Metastasis -1.62 -4.66 0.43 879.28 1.00 345 18 16 0 FALSE 0.65
uterine cancer KRAS_G12D CARD11 30 39 Primary -1.41 -3.89 0.45 763.53 1.00 612 29 38 1 FALSE 0.66
colorectal cancer KRAS_G12D CARD11 292 128 Tumor Type:overall -0.54 -2.27 0.81 1258.56 1.00 1825 278 114 14 FALSE 0.30
non-small cell lung cancer KRAS_G12D CARD11 151 130 Tumor Type:overall -0.96 -4.14 1.21 1345.12 1.00 3409 148 127 3 FALSE 0.34
uterine cancer KRAS_G12D CARD11 48 55 Tumor Type:overall -1.49 -4.22 0.49 949.45 1.00 957 47 54 1 FALSE 0.61
colorectal cancer KRAS_G12D DNMT3A 111 11 Metastasis -1.39 -3.52 0.36 1504.96 1.00 757 110 10 1 TRUE 0.78
colorectal cancer KRAS_G12D DNMT3A 180 45 Primary -1.83 -3.70 -0.47 1474.82 1.00 1123 179 44 1 TRUE 1.54
non-small cell lung cancer KRAS_G12D DNMT3A 45 27 Metastasis 0.55 -0.82 1.93 947.50 1.00 1313 42 24 3 TRUE 0.36
non-small cell lung cancer KRAS_G12D DNMT3A 106 50 Primary -0.24 -2.13 1.02 1079.83 1.00 2144 105 49 1 TRUE 0.12
colorectal cancer KRAS_G12D DNMT3A 291 56 Tumor Type:overall -1.58 -3.79 0.55 1449.40 1.00 1880 289 54 2 TRUE 0.85
non-small cell lung cancer KRAS_G12D DNMT3A 151 77 Tumor Type:overall 0.17 -1.64 1.74 1282.44 1.00 3457 147 73 4 TRUE 0.08
colorectal cancer KRAS_G12D MSH6 111 23 Metastasis -0.75 -2.39 0.39 1487.25 1.00 748 110 22 1 TRUE 0.54
colorectal cancer KRAS_G12D MSH6 182 77 Primary -0.15 -0.84 0.55 1596.65 1.00 1107 172 67 10 TRUE 0.17
uterine cancer KRAS_G12D MSH6 19 22 Metastasis 0.75 -0.42 1.92 1149.79 1.00 345 16 19 3 TRUE 0.68
uterine cancer KRAS_G12D MSH6 31 68 Primary 0.44 -0.63 1.29 1385.27 1.00 599 27 64 4 TRUE 0.44
colorectal cancer KRAS_G12D MSH6 293 100 Tumor Type:overall -0.43 -2.04 0.91 1407.55 1.00 1855 282 89 11 TRUE 0.24
uterine cancer KRAS_G12D MSH6 50 90 Tumor Type:overall 0.59 -0.64 1.84 1496.27 1.00 944 43 83 7 TRUE 0.44
non-small cell lung cancer KRAS_G12D MAX 45 16 Metastasis 1.59 0.62 2.59 1230.15 1.00 1324 42 13 3 FALSE 2.76
non-small cell lung cancer KRAS_G12D MAX 106 39 Primary 1.44 0.53 2.16 1335.68 1.00 2160 100 33 6 FALSE 3.35
non-small cell lung cancer KRAS_G12D MAX 151 55 Tumor Type:overall 1.49 0.32 2.52 1488.91 1.00 3484 142 46 9 FALSE 2.22
non-small cell lung cancer KRAS_G12D INPP4B 46 53 Metastasis 0.76 0.01 1.60 227.43 1.02 1293 41 48 5 FALSE 1.15
non-small cell lung cancer KRAS_G12D INPP4B 106 73 Primary 0.55 -0.36 1.32 1002.97 1.01 2130 101 68 5 FALSE 0.76
non-small cell lung cancer KRAS_G12D INPP4B 152 126 Tumor Type:overall 0.65 -0.35 1.70 979.51 1.00 3423 142 116 10 FALSE 0.69
non-small cell lung cancer KRAS_G12D NFE2L2 45 43 Metastasis -1.12 -2.92 0.35 976.39 1.00 1300 44 42 1 FALSE 0.72
non-small cell lung cancer KRAS_G12D NFE2L2 106 81 Primary -1.26 -3.07 0.09 1118.80 1.00 2120 105 80 1 FALSE 0.96
non-small cell lung cancer KRAS_G12D NFE2L2 151 124 Tumor Type:overall -1.18 -2.94 0.32 939.31 1.00 3420 149 122 2 FALSE 0.77
uterine cancer KRAS_G12D SPOP 18 14 Metastasis -1.13 -3.98 1.15 1323.79 1.00 346 17 13 1 FALSE 0.41
uterine cancer KRAS_G12D SPOP 30 44 Primary -1.87 -5.17 0.19 1209.04 1.00 602 30 44 0 FALSE 0.71
uterine cancer KRAS_G12D SPOP 48 58 Tumor Type:overall -1.47 -4.51 0.80 1287.41 1.00 948 47 57 1 FALSE 0.55
colorectal cancer KRAS_G12D SOX9 112 72 Metastasis -0.09 -0.81 0.49 1523.60 1.00 708 104 64 8 FALSE 0.11
colorectal cancer KRAS_G12D SOX9 183 192 Primary 0.20 -0.22 0.58 1521.78 1.00 1015 152 161 31 FALSE 0.49
colorectal cancer KRAS_G12D SOX9 295 264 Tumor Type:overall 0.07 -0.89 0.98 1533.82 1.00 1723 256 225 39 FALSE 0.05
colorectal cancer KRAS_G12D ETV1 111 14 Metastasis -0.37 -1.72 0.77 1433.51 1.00 755 109 12 2 TRUE 0.26
colorectal cancer KRAS_G12D ETV1 180 38 Primary -0.51 -1.72 0.35 1105.59 1.00 1129 177 35 3 TRUE 0.48
colorectal cancer KRAS_G12D ETV1 291 52 Tumor Type:overall -0.43 -1.74 0.69 1320.59 1.00 1884 286 47 5 TRUE 0.29
colorectal cancer KRAS_G12D ARAF 111 18 Metastasis -0.50 -1.61 0.51 1187.03 1.00 751 109 16 2 FALSE 0.46
colorectal cancer KRAS_G12D ARAF 180 37 Primary -0.54 -1.58 0.35 1231.09 1.00 1132 177 34 3 FALSE 0.56
non-small cell lung cancer KRAS_G12D ARAF 45 30 Metastasis -0.88 -3.88 0.65 563.73 1.00 1311 45 30 0 FALSE 0.34
non-small cell lung cancer KRAS_G12D ARAF 106 39 Primary -0.49 -2.40 0.73 793.72 1.00 2160 104 37 2 FALSE 0.27
colorectal cancer KRAS_G12D ARAF 291 55 Tumor Type:overall -0.52 -1.62 0.46 1379.93 1.00 1883 286 50 5 FALSE 0.46
non-small cell lung cancer KRAS_G12D ARAF 151 69 Tumor Type:overall -0.69 -2.87 0.81 464.37 1.01 3471 149 67 2 FALSE 0.33
non-small cell lung cancer KRAS_G12D JAK2 47 41 Metastasis -0.72 -2.65 0.79 1567.02 1.00 1348 46 40 1 TRUE 0.38
non-small cell lung cancer KRAS_G12D JAK2 109 37 Primary -0.75 -2.58 0.70 1249.02 1.00 2228 108 36 1 TRUE 0.42
non-small cell lung cancer KRAS_G12D JAK2 156 78 Tumor Type:overall -0.74 -2.73 1.04 1456.50 1.00 3576 154 76 2 TRUE 0.35
colorectal cancer KRAS_G12D SMAD2 111 26 Metastasis -2.12 -7.51 0.23 1066.95 1.00 743 111 26 0 TRUE 0.53
colorectal cancer KRAS_G12D SMAD2 182 76 Primary 0.63 0.08 1.20 1426.40 1.00 1110 164 58 18 TRUE 1.55
colorectal cancer KRAS_G12D SMAD2 293 102 Tumor Type:overall -0.61 -4.07 1.75 1164.85 1.00 1853 275 84 18 TRUE 0.18
non-small cell lung cancer KRAS_G12D TP63 45 33 Metastasis -1.36 -4.04 0.62 1373.72 1.00 1305 44 32 1 FALSE 0.59
non-small cell lung cancer KRAS_G12D TP63 106 39 Primary -1.85 -5.24 0.21 1154.88 1.00 2155 106 39 0 FALSE 0.69
non-small cell lung cancer KRAS_G12D TP63 151 72 Tumor Type:overall -1.58 -4.47 0.45 1303.42 1.00 3460 150 71 1 FALSE 0.66
colorectal cancer KRAS_G12D JUN 111 16 Metastasis -0.26 -1.37 0.71 778.86 1.01 754 109 14 2 FALSE 0.21
colorectal cancer KRAS_G12D JUN 181 37 Primary -0.27 -1.23 0.57 633.93 1.00 1129 177 33 4 FALSE 0.26
colorectal cancer KRAS_G12D JUN 292 53 Tumor Type:overall -0.28 -1.33 0.71 733.48 1.00 1883 286 47 6 FALSE 0.21
colorectal cancer KRAS_G12D DNMT3B 111 15 Metastasis -5.85 -12.66 -1.55 918.89 1.00 753 111 15 0 FALSE 1.37
colorectal cancer KRAS_G12D DNMT3B 180 49 Primary -5.88 -12.71 -1.84 926.37 1.00 1118 180 49 0 FALSE 1.45
colorectal cancer KRAS_G12D DNMT3B 291 64 Tumor Type:overall -5.71 -12.35 -1.65 900.40 1.00 1871 291 64 0 FALSE 1.42
non-small cell lung cancer KRAS_G12D MYOD1 45 25 Metastasis -0.42 -2.56 1.11 1355.90 1.00 1313 44 24 1 FALSE 0.19
non-small cell lung cancer KRAS_G12D MYOD1 106 33 Primary -0.52 -2.47 0.90 1324.86 1.00 2164 105 32 1 FALSE 0.26
non-small cell lung cancer KRAS_G12D MYOD1 151 58 Tumor Type:overall -0.46 -2.70 1.10 1329.12 1.00 3477 149 56 2 FALSE 0.21
colorectal cancer KRAS_G12D FGFR1 128 17 Metastasis 0.33 -0.66 1.50 525.63 1.00 815 123 12 5 TRUE 0.26
colorectal cancer KRAS_G12D FGFR1 204 34 Primary -0.31 -1.66 0.63 388.43 1.01 1265 202 32 2 TRUE 0.23
colorectal cancer KRAS_G12D FGFR1 332 51 Tumor Type:overall -0.01 -1.31 1.09 997.97 1.00 2080 325 44 7 TRUE 0.01
colorectal cancer KRAS_G12D MITF 111 14 Metastasis 0.06 -1.01 1.04 839.61 1.00 755 109 12 2 FALSE 0.04
colorectal cancer KRAS_G12D MITF 180 38 Primary 0.11 -0.74 0.92 538.95 1.00 1129 174 32 6 FALSE 0.10
colorectal cancer KRAS_G12D MITF 291 52 Tumor Type:overall 0.10 -1.02 1.16 840.65 1.00 1884 283 44 8 FALSE 0.06
non-small cell lung cancer KRAS_G12D BTK 45 28 Metastasis -1.55 -5.09 0.48 868.30 1.00 1309 45 28 0 TRUE 0.55
non-small cell lung cancer KRAS_G12D BTK 106 32 Primary -1.25 -4.03 0.52 877.49 1.00 2162 105 31 1 TRUE 0.52
non-small cell lung cancer KRAS_G12D BTK 151 60 Tumor Type:overall -1.37 -4.41 0.61 1003.58 1.00 3471 150 59 1 TRUE 0.52
colorectal cancer KRAS_G12D SH2B3 166 46 Primary -0.14 -1.02 0.73 874.62 1.00 1031 160 40 6 FALSE 0.12
colorectal cancer KRAS_G12D SH2B3 166 46 Tumor Type:overall -0.15 -4.60 4.15 1419.29 1.00 1031 160 40 6 FALSE 0.03
colorectal cancer KRAS_G12D GLI1 100 24 Metastasis -0.28 -1.26 0.63 1391.73 1.00 671 97 21 3 FALSE 0.26
colorectal cancer KRAS_G12D GLI1 166 63 Primary -0.36 -1.17 0.36 1402.63 1.00 1016 160 57 6 FALSE 0.46
non-small cell lung cancer KRAS_G12D GLI1 44 37 Metastasis -0.40 -1.86 0.93 1059.89 1.00 1160 42 35 2 FALSE 0.24
non-small cell lung cancer KRAS_G12D GLI1 95 69 Primary -0.71 -2.38 0.48 1188.38 1.00 1922 94 68 1 FALSE 0.48
colorectal cancer KRAS_G12D GLI1 266 87 Tumor Type:overall -0.32 -1.39 0.73 1627.95 1.00 1687 257 78 9 FALSE 0.25
non-small cell lung cancer KRAS_G12D GLI1 139 106 Tumor Type:overall -0.54 -2.16 0.77 1182.82 1.00 3082 136 103 3 FALSE 0.31
colorectal cancer KRAS_G12D ZFHX3 100 52 Metastasis -0.02 -0.72 0.68 1321.89 1.00 660 93 45 7 FALSE 0.02
colorectal cancer KRAS_G12D ZFHX3 168 174 Primary -0.15 -0.65 0.32 1335.88 1.00 963 148 154 20 FALSE 0.26
non-small cell lung cancer KRAS_G12D ZFHX3 44 75 Metastasis -0.24 -1.62 0.55 4.99 1.24 1120 42 73 2 FALSE 0.15
non-small cell lung cancer KRAS_G12D ZFHX3 95 89 Primary -0.22 -1.56 0.56 4.65 1.27 1905 92 86 3 FALSE 0.14
uterine cancer KRAS_G12D ZFHX3 19 65 Metastasis 0.95 0.05 2.05 1087.73 1.00 262 10 56 9 FALSE 1.18
uterine cancer KRAS_G12D ZFHX3 30 150 Primary 0.02 -0.98 0.86 1295.12 1.00 507 25 145 5 FALSE 0.01
colorectal cancer KRAS_G12D ZFHX3 268 226 Tumor Type:overall -0.07 -1.15 0.96 1441.49 1.00 1623 241 199 27 FALSE 0.05
non-small cell lung cancer KRAS_G12D ZFHX3 139 164 Tumor Type:overall -0.23 -1.62 0.61 5.81 1.21 3025 134 159 5 FALSE 0.13
uterine cancer KRAS_G12D ZFHX3 49 215 Tumor Type:overall 0.47 -0.95 1.88 1391.63 1.00 769 35 201 14 FALSE 0.30
colorectal cancer KRAS_G12D MST1R 99 19 Metastasis -1.39 -6.05 0.34 1333.07 1.00 675 99 19 0 FALSE 0.41
colorectal cancer KRAS_G12D MST1R 167 54 Primary 0.05 -0.76 0.78 1203.53 1.00 1030 158 45 9 FALSE 0.05
colorectal cancer KRAS_G12D MST1R 266 73 Tumor Type:overall -0.63 -3.41 1.00 1412.42 1.00 1705 257 64 9 FALSE 0.23
colorectal cancer KRAS_G12D MGA 99 29 Metastasis -0.30 -1.36 0.76 1408.08 1.00 667 95 25 4 FALSE 0.25
colorectal cancer KRAS_G12D MGA 165 94 Primary -0.78 -1.62 -0.10 1445.16 1.00 994 159 88 6 FALSE 1.34
non-small cell lung cancer KRAS_G12D MGA 44 82 Metastasis -1.65 -3.49 -0.29 1154.09 1.00 1127 43 81 1 FALSE 1.36
non-small cell lung cancer KRAS_G12D MGA 95 115 Primary -1.75 -3.64 -0.48 1137.95 1.00 1879 94 114 1 FALSE 1.56
uterine cancer KRAS_G12D MGA 20 34 Metastasis 0.72 -0.60 1.89 1457.35 1.00 278 15 29 5 FALSE 0.58
uterine cancer KRAS_G12D MGA 29 81 Primary -2.26 -7.72 0.18 1274.97 1.00 550 29 81 0 FALSE 0.48
colorectal cancer KRAS_G12D MGA 264 123 Tumor Type:overall -0.54 -1.82 0.81 1562.41 1.00 1661 254 113 10 FALSE 0.39
non-small cell lung cancer KRAS_G12D MGA 139 197 Tumor Type:overall -1.70 -3.65 -0.28 1208.46 1.00 3006 137 195 2 FALSE 1.35
uterine cancer KRAS_G12D MGA 49 115 Tumor Type:overall -0.68 -4.06 1.91 1242.60 1.00 828 44 110 5 FALSE 0.19
colorectal cancer KRAS_G12D TCF3 99 13 Metastasis -0.67 -2.24 0.66 1307.41 1.00 681 98 12 1 FALSE 0.44
colorectal cancer KRAS_G12D TCF3 166 55 Primary -0.54 -1.54 0.31 879.51 1.00 1020 161 50 5 FALSE 0.60
colorectal cancer KRAS_G12D TCF3 265 68 Tumor Type:overall -0.60 -2.25 0.94 1070.26 1.00 1701 259 62 6 FALSE 0.35
colorectal cancer KRAS_G12D KMT2B 59 39 Metastasis -0.46 -1.26 0.39 1391.58 1.00 286 54 34 5 FALSE 0.57
colorectal cancer KRAS_G12D KMT2B 101 143 Primary -0.59 -1.18 0.01 1234.34 1.00 587 90 132 11 FALSE 1.28
non-small cell lung cancer KRAS_G12D KMT2B 29 19 Metastasis -1.87 -5.19 0.31 903.90 1.00 629 29 19 0 FALSE 0.73
non-small cell lung cancer KRAS_G12D KMT2B 54 52 Primary -1.68 -4.58 0.28 933.39 1.00 1101 53 51 1 FALSE 0.76
colorectal cancer KRAS_G12D KMT2B 160 182 Tumor Type:overall -0.50 -1.53 0.65 1529.38 1.00 873 144 166 16 FALSE 0.43
non-small cell lung cancer KRAS_G12D KMT2B 83 71 Tumor Type:overall -1.75 -4.75 0.48 959.80 1.00 1730 82 70 1 FALSE 0.72
colorectal cancer KRAS_G12D TCF7L2 101 97 Metastasis 0.25 -0.24 0.72 1047.00 1.00 615 86 82 15 FALSE 0.50
colorectal cancer KRAS_G12D TCF7L2 168 202 Primary 0.29 -0.11 0.67 1015.34 1.00 914 135 169 33 FALSE 0.84
colorectal cancer KRAS_G12D TCF7L2 269 299 Tumor Type:overall 0.28 -0.27 0.88 1151.38 1.00 1529 221 251 48 FALSE 0.44
colorectal cancer KRAS_G12D MSH3 59 18 Metastasis -0.69 -2.06 0.37 1535.29 1.00 290 57 16 2 FALSE 0.59
colorectal cancer KRAS_G12D MSH3 98 71 Primary -0.71 -1.72 0.04 1459.70 1.00 617 93 66 5 FALSE 0.94
colorectal cancer KRAS_G12D MSH3 157 89 Tumor Type:overall -0.72 -2.06 0.46 1468.99 1.00 907 150 82 7 FALSE 0.56
colorectal cancer KRAS_G12D ANKRD11 101 36 Metastasis -0.55 -1.54 0.26 1320.78 1.00 666 98 33 3 FALSE 0.64
colorectal cancer KRAS_G12D ANKRD11 167 110 Primary -0.51 -1.19 0.14 1567.78 1.00 990 157 100 10 FALSE 0.90
non-small cell lung cancer KRAS_G12D ANKRD11 44 27 Metastasis 0.46 -0.73 1.47 1296.25 1.00 1169 42 25 2 FALSE 0.41
non-small cell lung cancer KRAS_G12D ANKRD11 96 45 Primary 0.42 -0.71 1.30 1302.29 1.00 1945 93 42 3 FALSE 0.40
colorectal cancer KRAS_G12D ANKRD11 268 146 Tumor Type:overall -0.52 -1.69 0.54 1453.20 1.00 1656 255 133 13 FALSE 0.42
non-small cell lung cancer KRAS_G12D ANKRD11 140 72 Tumor Type:overall 0.45 -0.79 1.48 1116.22 1.00 3114 135 67 5 FALSE 0.36
colorectal cancer KRAS_G12D PGR 100 11 Metastasis 0.36 -1.02 1.77 1415.00 1.00 684 97 8 3 FALSE 0.22
colorectal cancer KRAS_G12D PGR 166 52 Primary -0.52 -1.60 0.36 1722.51 1.00 1022 162 48 4 FALSE 0.54
non-small cell lung cancer KRAS_G12D PGR 44 34 Metastasis -0.38 -1.85 0.80 1045.49 1.00 1158 43 33 1 FALSE 0.24
non-small cell lung cancer KRAS_G12D PGR 95 53 Primary -0.37 -1.74 0.75 768.94 1.00 1939 93 51 2 FALSE 0.25
colorectal cancer KRAS_G12D PGR 266 63 Tumor Type:overall -0.09 -1.77 1.74 1399.32 1.00 1706 259 56 7 FALSE 0.04
non-small cell lung cancer KRAS_G12D PGR 139 87 Tumor Type:overall -0.38 -1.83 0.80 913.11 1.00 3097 136 84 3 FALSE 0.24
colorectal cancer KRAS_G12D PLCG2 100 22 Metastasis -0.16 -1.35 0.75 1209.76 1.00 673 98 20 2 FALSE 0.12
colorectal cancer KRAS_G12D PLCG2 166 63 Primary 0.10 -0.63 0.75 1590.84 1.00 1018 156 53 10 FALSE 0.12
non-small cell lung cancer KRAS_G12D PLCG2 44 24 Metastasis -4.74 -11.43 -0.57 534.05 1.00 1168 44 24 0 FALSE 1.01
non-small cell lung cancer KRAS_G12D PLCG2 95 38 Primary -4.74 -11.61 -0.79 525.18 1.01 1955 95 38 0 FALSE 1.00
colorectal cancer KRAS_G12D PLCG2 266 85 Tumor Type:overall -0.01 -1.15 0.94 1204.50 1.00 1691 254 73 12 FALSE 0.01
non-small cell lung cancer KRAS_G12D PLCG2 139 62 Tumor Type:overall -4.70 -11.50 -0.73 525.78 1.01 3123 139 62 0 FALSE 1.00
colorectal cancer KRAS_G12D POLD1 99 20 Metastasis -0.97 -2.73 0.35 1396.83 1.00 677 98 19 1 TRUE 0.71
colorectal cancer KRAS_G12D POLD1 168 92 Primary -0.59 -1.34 0.13 1516.03 1.00 1002 160 84 8 TRUE 0.96
non-small cell lung cancer KRAS_G12D POLD1 44 25 Metastasis 0.19 -1.34 1.46 1162.87 1.00 1167 42 23 2 TRUE 0.11
non-small cell lung cancer KRAS_G12D POLD1 95 33 Primary -0.05 -1.64 1.23 1117.63 1.00 1957 94 32 1 TRUE 0.02
colorectal cancer KRAS_G12D POLD1 267 112 Tumor Type:overall -0.74 -2.41 0.81 1342.71 1.00 1679 258 103 9 TRUE 0.41
non-small cell lung cancer KRAS_G12D POLD1 139 58 Tumor Type:overall 0.07 -1.46 1.47 1142.95 1.00 3124 136 55 3 TRUE 0.04
colorectal cancer KRAS_G12D INHBA 99 20 Metastasis 0.35 -0.51 1.28 1105.42 1.00 677 94 15 5 FALSE 0.36
colorectal cancer KRAS_G12D INHBA 165 34 Primary 0.14 -0.75 0.90 964.58 1.00 1037 161 30 4 FALSE 0.13
non-small cell lung cancer KRAS_G12D INHBA 44 32 Metastasis -1.86 -4.87 0.09 677.68 1.01 1163 44 32 0 FALSE 0.85
non-small cell lung cancer KRAS_G12D INHBA 95 55 Primary -1.72 -4.39 0.00 641.00 1.00 1935 94 54 1 FALSE 0.92
colorectal cancer KRAS_G12D INHBA 264 54 Tumor Type:overall 0.24 -0.76 1.12 1132.08 1.00 1714 255 45 9 FALSE 0.20
non-small cell lung cancer KRAS_G12D INHBA 139 87 Tumor Type:overall -1.79 -4.67 0.04 759.39 1.00 3098 138 86 1 FALSE 0.87
colorectal cancer KRAS_G12D PREX2 58 31 Metastasis 0.03 -0.80 0.88 466.46 1.00 287 51 24 7 FALSE 0.02
colorectal cancer KRAS_G12D PREX2 99 60 Primary -0.38 -1.35 0.35 909.65 1.00 624 95 56 4 FALSE 0.43
non-small cell lung cancer KRAS_G12D PREX2 29 42 Metastasis -0.64 -2.19 0.58 1405.64 1.00 611 28 41 1 FALSE 0.45
non-small cell lung cancer KRAS_G12D PREX2 54 63 Primary -0.61 -2.10 0.51 1379.89 1.00 1093 52 61 2 FALSE 0.45
colorectal cancer KRAS_G12D PREX2 157 91 Tumor Type:overall -0.18 -1.24 0.82 754.13 1.00 911 146 80 11 FALSE 0.13
non-small cell lung cancer KRAS_G12D PREX2 83 105 Tumor Type:overall -0.63 -2.18 0.59 1165.67 1.00 1704 80 102 3 FALSE 0.42
colorectal cancer KRAS_G12D AMER1 111 51 Metastasis 0.15 -0.47 0.75 1367.10 1.00 726 103 43 8 FALSE 0.21
colorectal cancer KRAS_G12D AMER1 180 118 Primary 0.12 -0.36 0.56 1358.61 1.00 1071 163 101 17 FALSE 0.21
non-small cell lung cancer KRAS_G12D AMER1 45 54 Metastasis -0.22 -1.55 0.69 182.68 1.02 1293 44 53 1 FALSE 0.15
non-small cell lung cancer KRAS_G12D AMER1 106 95 Primary -0.07 -1.06 0.73 236.01 1.01 2114 101 90 5 FALSE 0.06
uterine cancer KRAS_G12D AMER1 18 14 Metastasis -0.34 -2.38 1.28 1262.58 1.00 351 17 13 1 FALSE 0.15
uterine cancer KRAS_G12D AMER1 30 42 Primary -0.54 -2.52 0.86 1339.36 1.00 615 29 41 1 FALSE 0.27
colorectal cancer KRAS_G12D AMER1 291 169 Tumor Type:overall 0.14 -0.60 0.86 1413.17 1.00 1797 266 144 25 FALSE 0.14
non-small cell lung cancer KRAS_G12D AMER1 151 149 Tumor Type:overall -0.15 -1.37 0.83 559.13 1.01 3407 145 143 6 FALSE 0.08
uterine cancer KRAS_G12D AMER1 48 56 Tumor Type:overall -0.45 -2.52 1.22 1343.47 1.00 966 46 54 2 FALSE 0.20
colorectal cancer KRAS_G12D HLA-A 165 42 Primary -0.51 -1.70 0.48 1323.27 1.00 1035 161 38 4 FALSE 0.44
colorectal cancer KRAS_G12D HLA-A 165 42 Tumor Type:overall -0.46 -5.36 3.99 1368.93 1.00 1035 161 38 4 FALSE 0.08
colorectal cancer KRAS_G12D EPHA7 99 23 Metastasis -0.09 -1.05 0.70 448.74 1.02 672 96 20 3 FALSE 0.08
colorectal cancer KRAS_G12D EPHA7 166 67 Primary -0.09 -0.84 0.47 44.92 1.05 1017 158 59 8 FALSE 0.11
non-small cell lung cancer KRAS_G12D EPHA7 45 54 Metastasis 0.14 -1.01 1.21 1055.03 1.00 1142 41 50 4 FALSE 0.09
non-small cell lung cancer KRAS_G12D EPHA7 95 75 Primary -0.55 -2.39 0.54 1242.45 1.00 1917 94 74 1 FALSE 0.35
colorectal cancer KRAS_G12D EPHA7 265 90 Tumor Type:overall -0.06 -1.19 0.76 73.96 1.04 1689 254 79 11 FALSE 0.05
non-small cell lung cancer KRAS_G12D EPHA7 140 129 Tumor Type:overall -0.17 -1.85 1.22 1546.37 1.00 3059 135 124 5 FALSE 0.08
colorectal cancer KRAS_G12D NCOA3 99 14 Metastasis -0.65 -2.08 0.52 1314.43 1.00 680 98 13 1 TRUE 0.49
colorectal cancer KRAS_G12D NCOA3 165 42 Primary -0.53 -1.60 0.40 1482.17 1.00 1030 161 38 4 TRUE 0.52
colorectal cancer KRAS_G12D NCOA3 264 56 Tumor Type:overall -0.56 -1.98 0.79 1324.40 1.00 1710 259 51 5 TRUE 0.38
non-small cell lung cancer KRAS_G12D DROSHA 29 19 Metastasis -4.97 -12.01 -0.75 361.06 1.01 627 29 19 0 FALSE 1.06
non-small cell lung cancer KRAS_G12D DROSHA 54 35 Primary -4.99 -11.88 -0.82 370.52 1.01 1115 54 35 0 FALSE 1.10
non-small cell lung cancer KRAS_G12D DROSHA 83 54 Tumor Type:overall -4.93 -11.84 -0.66 396.21 1.01 1742 83 54 0 FALSE 1.07
colorectal cancer KRAS_G12D SLX4 58 13 Metastasis -0.15 -1.25 0.81 1113.87 1.00 295 56 11 2 FALSE 0.11
colorectal cancer KRAS_G12D SLX4 98 41 Primary -0.11 -1.04 0.73 1069.63 1.00 641 93 36 5 FALSE 0.09
colorectal cancer KRAS_G12D SLX4 156 54 Tumor Type:overall -0.13 -1.26 0.97 1204.81 1.00 936 149 47 7 FALSE 0.08
colorectal cancer KRAS_G12D INPPL1 58 15 Metastasis -1.23 -2.75 0.06 244.35 1.02 295 57 14 1 FALSE 1.15
colorectal cancer KRAS_G12D INPPL1 98 58 Primary -1.19 -2.37 -0.18 78.73 1.05 631 95 55 3 FALSE 1.48
colorectal cancer KRAS_G12D INPPL1 156 73 Tumor Type:overall -1.20 -2.70 0.13 258.15 1.03 926 152 69 4 FALSE 1.05
colorectal cancer KRAS_G12V SPEN 73 45 Metastasis -2.26 -3.87 -0.59 42.41 1.08 770 72 44 1 FALSE 2.13
colorectal cancer KRAS_G12V SPEN 121 110 Primary -2.43 -4.10 -1.02 63.01 1.06 1143 120 109 1 FALSE 2.65
non-small cell lung cancer KRAS_G12V SPEN 50 71 Metastasis -0.26 -1.51 0.83 1452.46 1.00 1291 48 69 2 FALSE 0.17
non-small cell lung cancer KRAS_G12V SPEN 119 50 Primary -0.07 -1.25 0.94 1472.55 1.00 2136 116 47 3 FALSE 0.05
uterine cancer KRAS_G12V SPEN 18 38 Metastasis -0.97 -2.35 0.34 962.70 1.00 334 17 37 1 FALSE 0.81
uterine cancer KRAS_G12V SPEN 38 82 Primary -0.99 -2.30 0.12 852.93 1.00 589 36 80 2 FALSE 0.94
colorectal cancer KRAS_G12V SPEN 194 155 Tumor Type:overall -2.33 -3.93 -0.73 50.19 1.08 1913 192 153 2 FALSE 2.14
non-small cell lung cancer KRAS_G12V SPEN 169 121 Tumor Type:overall -0.17 -1.75 1.36 1522.87 1.00 3427 164 116 5 FALSE 0.08
uterine cancer KRAS_G12V SPEN 56 120 Tumor Type:overall -0.98 -2.46 0.25 872.07 1.00 923 53 117 3 FALSE 0.83
colorectal cancer KRAS_G12V KMT2C 73 49 Metastasis -1.12 -2.34 0.04 1567.71 1.00 765 71 47 2 FALSE 1.18
colorectal cancer KRAS_G12V KMT2C 122 149 Primary -1.32 -2.31 -0.49 1436.82 1.00 1123 118 145 4 FALSE 2.32
non-small cell lung cancer KRAS_G12V KMT2C 51 89 Metastasis 0.60 -0.06 1.33 1279.05 1.00 1258 44 82 7 FALSE 1.07
non-small cell lung cancer KRAS_G12V KMT2C 119 133 Primary 0.42 -0.23 0.96 798.43 1.00 2064 110 124 9 FALSE 0.75
uterine cancer KRAS_G12V KMT2C 18 45 Metastasis -1.14 -4.22 0.29 653.57 1.00 330 18 45 0 FALSE 0.41
uterine cancer KRAS_G12V KMT2C 38 106 Primary -0.51 -1.55 0.49 871.14 1.00 576 33 101 5 FALSE 0.48
colorectal cancer KRAS_G12V KMT2C 195 198 Tumor Type:overall -1.21 -2.60 0.08 1469.59 1.00 1888 189 192 6 FALSE 1.03
non-small cell lung cancer KRAS_G12V KMT2C 170 222 Tumor Type:overall 0.49 -0.40 1.28 891.07 1.00 3322 154 206 16 FALSE 0.59
uterine cancer KRAS_G12V KMT2C 56 151 Tumor Type:overall -0.78 -2.65 0.65 1007.07 1.00 906 51 146 5 FALSE 0.43
cancer of unknown primary KRAS_G12V TP53 46 392 Metastasis 0.21 -0.39 0.88 282.35 1.01 329 20 366 26 TRUE 0.29
colorectal cancer KRAS_G12V TP53 81 701 Metastasis -0.96 -1.38 -0.56 1426.51 1.00 247 43 663 38 TRUE 5.28
colorectal cancer KRAS_G12V TP53 141 1018 Primary -0.64 -0.96 -0.30 1184.64 1.00 498 67 944 74 TRUE 3.84
non-small cell lung cancer KRAS_G12V TP53 53 855 Metastasis -0.60 -1.09 -0.13 1556.39 1.00 595 29 831 24 TRUE 1.85
non-small cell lung cancer KRAS_G12V TP53 125 1201 Primary -0.66 -1.03 -0.31 1490.16 1.00 1186 84 1160 41 TRUE 3.44
pancreatic cancer KRAS_G12V TP53 129 379 Metastasis 0.80 0.46 1.19 1503.77 1.00 197 29 279 100 TRUE 4.78
pancreatic cancer KRAS_G12V TP53 257 567 Primary 0.82 0.52 1.11 1440.26 1.00 293 68 378 189 TRUE 7.51
uterine cancer KRAS_G12V TP53 19 180 Metastasis -1.45 -2.10 -0.76 117.86 1.03 218 16 177 3 TRUE 4.97
uterine cancer KRAS_G12V TP53 46 361 Primary -1.41 -1.99 -0.80 21.75 1.06 403 37 352 9 TRUE 5.98
cancer of unknown primary KRAS_G12V TP53 49 420 Tumor Type:overall 0.29 -0.89 1.81 1221.03 1.00 372 21 392 28 TRUE 0.17
colorectal cancer KRAS_G12V TP53 222 1719 Tumor Type:overall -0.82 -1.55 -0.15 1251.17 1.00 745 110 1607 112 TRUE 1.40
non-small cell lung cancer KRAS_G12V TP53 178 2056 Tumor Type:overall -0.62 -1.43 0.30 1375.20 1.00 1781 113 1991 65 TRUE 0.83
pancreatic cancer KRAS_G12V TP53 386 946 Tumor Type:overall 0.81 0.26 1.43 1473.83 1.00 490 97 657 289 TRUE 2.12
uterine cancer KRAS_G12V TP53 65 541 Tumor Type:overall -1.42 -2.08 -0.72 85.22 1.04 621 53 529 12 TRUE 4.69
colorectal cancer KRAS_G12V ATRX 73 33 Metastasis -0.91 -2.28 0.22 653.31 1.01 777 72 32 1 TRUE 0.81
colorectal cancer KRAS_G12V ATRX 121 86 Primary -0.72 -1.64 0.10 81.59 1.04 1155 116 81 5 TRUE 0.88
non-small cell lung cancer KRAS_G12V ATRX 50 79 Metastasis -0.04 -1.18 0.81 517.26 1.00 1266 48 77 2 TRUE 0.03
non-small cell lung cancer KRAS_G12V ATRX 120 129 Primary 0.18 -0.54 0.82 442.41 1.01 2075 111 120 9 TRUE 0.22
uterine cancer KRAS_G12V ATRX 18 48 Metastasis -2.85 -5.89 -0.81 929.64 1.00 322 18 48 0 TRUE 1.55
uterine cancer KRAS_G12V ATRX 38 128 Primary -2.69 -5.17 -0.87 885.02 1.01 578 37 127 1 TRUE 1.79
colorectal cancer KRAS_G12V ATRX 194 119 Tumor Type:overall -0.80 -2.10 0.41 248.40 1.01 1932 188 113 6 TRUE 0.63
non-small cell lung cancer KRAS_G12V ATRX 170 208 Tumor Type:overall 0.08 -0.97 0.92 838.51 1.00 3341 159 197 11 TRUE 0.05
uterine cancer KRAS_G12V ATRX 56 176 Tumor Type:overall -2.76 -5.62 -0.72 880.75 1.01 900 55 175 1 TRUE 1.63
colorectal cancer KRAS_G12V ATR 73 30 Metastasis -2.00 -4.91 -0.36 1247.52 1.00 783 73 30 0 FALSE 0.93
colorectal cancer KRAS_G12V ATR 121 84 Primary -1.40 -2.77 -0.27 1510.15 1.00 1161 118 81 3 FALSE 1.50
non-small cell lung cancer KRAS_G12V ATR 50 53 Metastasis -1.01 -2.93 0.58 978.57 1.00 1283 48 51 2 FALSE 0.61
non-small cell lung cancer KRAS_G12V ATR 119 76 Primary -1.90 -5.02 -0.21 673.27 1.00 2106 119 76 0 FALSE 0.78
uterine cancer KRAS_G12V ATR 18 24 Metastasis -5.49 -12.18 -1.15 1042.48 1.00 346 18 24 0 FALSE 1.25
uterine cancer KRAS_G12V ATR 38 74 Primary -5.55 -12.38 -1.49 967.83 1.00 591 38 74 0 FALSE 1.32
colorectal cancer KRAS_G12V ATR 194 114 Tumor Type:overall -1.64 -3.75 -0.05 1629.89 1.00 1944 191 111 3 FALSE 1.05
non-small cell lung cancer KRAS_G12V ATR 169 129 Tumor Type:overall -1.44 -3.70 0.25 1043.79 1.00 3389 167 127 2 FALSE 0.78
uterine cancer KRAS_G12V ATR 56 98 Tumor Type:overall -5.41 -12.00 -1.36 986.75 1.00 937 56 98 0 FALSE 1.30
colorectal cancer KRAS_G12V PDGFRA 81 15 Metastasis -0.26 -1.76 0.90 1040.56 1.00 859 80 14 1 TRUE 0.16
colorectal cancer KRAS_G12V PDGFRA 135 45 Primary -0.15 -1.25 0.78 925.68 1.00 1325 131 41 4 TRUE 0.11
non-small cell lung cancer KRAS_G12V PDGFRA 52 64 Metastasis -1.04 -2.73 0.20 1197.14 1.00 1320 51 63 1 TRUE 0.81
non-small cell lung cancer KRAS_G12V PDGFRA 124 84 Primary -1.04 -2.52 0.05 1158.50 1.00 2173 122 82 2 TRUE 0.90
colorectal cancer KRAS_G12V PDGFRA 216 60 Tumor Type:overall -0.20 -1.66 0.98 872.64 1.00 2184 211 55 5 TRUE 0.12
non-small cell lung cancer KRAS_G12V PDGFRA 176 148 Tumor Type:overall -1.04 -2.76 0.20 1085.36 1.00 3493 173 145 3 TRUE 0.80
colorectal cancer KRAS_G12V FBXW7 82 90 Metastasis -0.56 -1.38 0.18 1469.87 1.00 798 77 85 5 TRUE 0.80
colorectal cancer KRAS_G12V FBXW7 136 249 Primary -0.51 -1.05 0.00 1275.33 1.00 1159 121 234 15 TRUE 1.27
non-small cell lung cancer KRAS_G12V FBXW7 52 32 Metastasis -0.20 -1.77 0.94 1435.05 1.00 1351 51 31 1 TRUE 0.11
non-small cell lung cancer KRAS_G12V FBXW7 124 54 Primary -0.13 -1.36 0.88 1155.55 1.00 2202 121 51 3 TRUE 0.09
uterine cancer KRAS_G12V FBXW7 19 38 Metastasis -0.65 -2.01 0.84 1430.41 1.00 345 17 36 2 TRUE 0.43
uterine cancer KRAS_G12V FBXW7 45 107 Primary -1.03 -2.38 0.03 1372.68 1.00 630 43 105 2 TRUE 1.03
colorectal cancer KRAS_G12V FBXW7 218 339 Tumor Type:overall -0.52 -1.49 0.55 1503.73 1.00 1957 198 319 20 TRUE 0.52
non-small cell lung cancer KRAS_G12V FBXW7 176 86 Tumor Type:overall -0.16 -1.60 1.05 1160.36 1.00 3553 172 82 4 TRUE 0.09
uterine cancer KRAS_G12V FBXW7 64 145 Tumor Type:overall -0.82 -2.32 0.54 1424.59 1.00 975 60 141 4 TRUE 0.56
colorectal cancer KRAS_G12V MAP3K1 73 30 Metastasis -0.72 -2.03 0.24 1155.86 1.00 778 72 29 1 FALSE 0.66
colorectal cancer KRAS_G12V MAP3K1 121 62 Primary -0.60 -1.64 0.27 777.04 1.00 1170 117 58 4 FALSE 0.65
non-small cell lung cancer KRAS_G12V MAP3K1 50 30 Metastasis -1.14 -4.25 0.62 1128.17 1.00 1303 50 30 0 FALSE 0.42
non-small cell lung cancer KRAS_G12V MAP3K1 120 37 Primary -0.61 -2.51 0.83 726.57 1.00 2144 118 35 2 FALSE 0.34
uterine cancer KRAS_G12V MAP3K1 18 16 Metastasis -5.50 -12.54 -0.63 248.58 1.02 345 18 16 0 FALSE 1.06
uterine cancer KRAS_G12V MAP3K1 38 55 Primary -5.57 -12.75 -1.13 245.50 1.02 591 38 55 0 FALSE 1.14
colorectal cancer KRAS_G12V MAP3K1 194 92 Tumor Type:overall -0.64 -1.82 0.39 984.32 1.00 1948 189 87 5 FALSE 0.56
non-small cell lung cancer KRAS_G12V MAP3K1 170 67 Tumor Type:overall -0.86 -3.34 0.84 902.65 1.00 3447 168 65 2 FALSE 0.38
uterine cancer KRAS_G12V MAP3K1 56 71 Tumor Type:overall -5.45 -12.49 -0.77 230.77 1.02 936 56 71 0 FALSE 1.11
colorectal cancer KRAS_G12V NSD1 73 23 Metastasis -1.40 -4.51 0.10 1124.16 1.00 784 73 23 0 FALSE 0.62
colorectal cancer KRAS_G12V NSD1 122 63 Primary -0.73 -1.92 0.26 1414.39 1.00 1171 118 59 4 FALSE 0.71
non-small cell lung cancer KRAS_G12V NSD1 50 34 Metastasis -0.01 -1.35 1.06 1308.00 1.00 1300 49 33 1 FALSE 0.01
non-small cell lung cancer KRAS_G12V NSD1 119 56 Primary 0.12 -0.97 1.01 1153.56 1.00 2127 115 52 4 FALSE 0.09
uterine cancer KRAS_G12V NSD1 19 32 Metastasis 0.14 -1.07 1.32 1452.78 1.00 337 16 29 3 FALSE 0.08
uterine cancer KRAS_G12V NSD1 38 91 Primary -0.33 -1.46 0.57 1335.56 1.00 581 35 88 3 FALSE 0.28
colorectal cancer KRAS_G12V NSD1 195 86 Tumor Type:overall -1.03 -3.15 0.44 1414.99 1.00 1955 191 82 4 FALSE 0.54
non-small cell lung cancer KRAS_G12V NSD1 169 90 Tumor Type:overall 0.04 -1.19 1.12 1198.05 1.00 3427 164 85 5 FALSE 0.02
uterine cancer KRAS_G12V NSD1 57 123 Tumor Type:overall -0.13 -1.50 1.17 1348.46 1.00 918 51 117 6 FALSE 0.07
colorectal cancer KRAS_G12V FLT4 73 41 Metastasis -1.04 -2.42 0.06 1274.09 1.00 767 72 40 1 TRUE 1.02
colorectal cancer KRAS_G12V FLT4 122 98 Primary -0.84 -1.77 -0.03 1124.60 1.00 1141 117 93 5 TRUE 1.21
non-small cell lung cancer KRAS_G12V FLT4 50 37 Metastasis -0.19 -1.60 1.06 521.07 1.00 1298 48 35 2 TRUE 0.11
non-small cell lung cancer KRAS_G12V FLT4 119 65 Primary -0.44 -1.72 0.60 585.02 1.00 2119 117 63 2 TRUE 0.33
uterine cancer KRAS_G12V FLT4 38 43 Primary -0.45 -2.29 0.86 1024.25 1.00 605 36 41 2 TRUE 0.24
colorectal cancer KRAS_G12V FLT4 195 139 Tumor Type:overall -0.93 -2.13 0.17 1207.15 1.00 1908 189 133 6 TRUE 0.84
non-small cell lung cancer KRAS_G12V FLT4 169 102 Tumor Type:overall -0.30 -1.68 1.02 542.61 1.00 3417 165 98 4 TRUE 0.17
uterine cancer KRAS_G12V FLT4 38 43 Tumor Type:overall -0.49 -4.91 4.08 1393.38 1.00 605 36 41 2 TRUE 0.08
colorectal cancer KRAS_G12V PTPRD 73 28 Metastasis -2.15 -5.09 -0.45 1273.91 1.00 781 73 28 0 FALSE 0.99
colorectal cancer KRAS_G12V PTPRD 121 75 Primary -1.76 -3.64 -0.43 1495.22 1.00 1163 119 73 2 FALSE 1.61
non-small cell lung cancer KRAS_G12V PTPRD 52 165 Metastasis 0.11 -0.57 0.73 1386.04 1.00 1202 45 158 7 FALSE 0.14
non-small cell lung cancer KRAS_G12V PTPRD 119 226 Primary 0.11 -0.44 0.60 1103.32 1.00 1996 106 213 13 FALSE 0.16
uterine cancer KRAS_G12V PTPRD 18 25 Metastasis -1.11 -3.08 0.62 1447.77 1.00 344 17 24 1 FALSE 0.64
uterine cancer KRAS_G12V PTPRD 38 74 Primary -1.36 -3.37 -0.04 1350.93 1.00 595 37 73 1 FALSE 1.00
colorectal cancer KRAS_G12V PTPRD 194 103 Tumor Type:overall -1.93 -4.11 -0.32 1220.33 1.00 1944 192 101 2 FALSE 1.26
non-small cell lung cancer KRAS_G12V PTPRD 171 391 Tumor Type:overall 0.10 -0.66 0.85 1489.34 1.00 3198 151 371 20 FALSE 0.09
uterine cancer KRAS_G12V PTPRD 56 99 Tumor Type:overall -1.22 -3.19 0.44 1466.73 1.00 939 54 97 2 FALSE 0.71
colorectal cancer KRAS_G12V RET 81 20 Metastasis -0.96 -2.86 0.67 881.96 1.00 855 79 18 2 TRUE 0.56
colorectal cancer KRAS_G12V RET 135 45 Primary -1.86 -5.32 -0.25 848.61 1.00 1319 135 45 0 TRUE 0.82
non-small cell lung cancer KRAS_G12V RET 52 39 Metastasis 0.18 -1.33 1.17 1481.39 1.00 1341 51 38 1 TRUE 0.11
non-small cell lung cancer KRAS_G12V RET 124 54 Primary 0.57 -0.35 1.40 1533.66 1.00 2205 118 48 6 TRUE 0.70
colorectal cancer KRAS_G12V RET 216 65 Tumor Type:overall -1.37 -3.65 0.45 1293.05 1.00 2174 214 63 2 TRUE 0.71
non-small cell lung cancer KRAS_G12V RET 176 93 Tumor Type:overall 0.39 -1.10 1.49 1644.29 1.00 3546 169 86 7 TRUE 0.27
colorectal cancer KRAS_G12V KDM5A 73 24 Metastasis -1.58 -3.68 0.05 1346.66 1.00 791 72 23 1 FALSE 1.03
colorectal cancer KRAS_G12V KDM5A 121 72 Primary -1.88 -3.90 -0.52 1052.91 1.00 1157 120 71 1 FALSE 1.50
non-small cell lung cancer KRAS_G12V KDM5A 50 24 Metastasis 0.44 -0.89 1.53 1233.60 1.00 1310 48 22 2 FALSE 0.33
non-small cell lung cancer KRAS_G12V KDM5A 119 49 Primary 0.29 -0.82 1.31 610.67 1.00 2137 116 46 3 FALSE 0.24
uterine cancer KRAS_G12V KDM5A 18 23 Metastasis -0.82 -2.79 0.58 1063.94 1.00 340 17 22 1 FALSE 0.47
uterine cancer KRAS_G12V KDM5A 38 42 Primary -0.87 -2.73 0.46 970.60 1.01 608 37 41 1 FALSE 0.54
colorectal cancer KRAS_G12V KDM5A 194 96 Tumor Type:overall -1.73 -3.93 0.00 1178.43 1.00 1948 192 94 2 FALSE 1.07
non-small cell lung cancer KRAS_G12V KDM5A 169 73 Tumor Type:overall 0.37 -0.89 1.52 1122.03 1.00 3447 164 68 5 FALSE 0.24
uterine cancer KRAS_G12V KDM5A 56 65 Tumor Type:overall -0.85 -2.87 0.65 1037.64 1.00 948 54 63 2 FALSE 0.46
colorectal cancer KRAS_G12V PIK3C2G 73 20 Metastasis 0.15 -1.04 1.29 1524.17 1.00 791 70 17 3 FALSE 0.09
colorectal cancer KRAS_G12V PIK3C2G 121 67 Primary -0.34 -1.38 0.50 1480.98 1.00 1168 117 63 4 FALSE 0.32
non-small cell lung cancer KRAS_G12V PIK3C2G 50 52 Metastasis -1.61 -3.94 -0.08 788.20 1.01 1283 50 52 0 FALSE 0.94
non-small cell lung cancer KRAS_G12V PIK3C2G 119 79 Primary -1.34 -3.07 -0.11 874.04 1.01 2107 117 77 2 FALSE 1.07
colorectal cancer KRAS_G12V PIK3C2G 194 87 Tumor Type:overall -0.10 -1.67 1.27 1495.82 1.00 1959 187 80 7 FALSE 0.05
non-small cell lung cancer KRAS_G12V PIK3C2G 169 131 Tumor Type:overall -1.46 -3.46 -0.03 906.37 1.00 3390 167 129 2 FALSE 0.97
non-small cell lung cancer KRAS_G12V TSHR 50 34 Metastasis -0.87 -4.21 0.73 1133.96 1.00 1300 50 34 0 TRUE 0.29
non-small cell lung cancer KRAS_G12V TSHR 119 35 Primary 0.02 -1.45 1.14 1365.49 1.00 2148 116 32 3 TRUE 0.01
non-small cell lung cancer KRAS_G12V TSHR 169 69 Tumor Type:overall -0.39 -2.67 1.20 1324.66 1.00 3448 166 66 3 TRUE 0.16
colorectal cancer KRAS_G12V CREBBP 73 37 Metastasis -1.25 -2.89 -0.01 1482.02 1.00 777 72 36 1 TRUE 1.05
colorectal cancer KRAS_G12V CREBBP 121 151 Primary -1.03 -1.90 -0.25 1287.99 1.00 1112 115 145 6 TRUE 1.83
non-small cell lung cancer KRAS_G12V CREBBP 50 67 Metastasis 0.66 -0.31 1.51 1322.43 1.00 1279 44 61 6 TRUE 0.80
non-small cell lung cancer KRAS_G12V CREBBP 119 75 Primary 0.02 -1.08 0.85 1193.99 1.00 2109 116 72 3 TRUE 0.02
uterine cancer KRAS_G12V CREBBP 19 26 Metastasis 0.73 -0.78 2.10 1036.68 1.00 342 15 22 4 TRUE 0.50
uterine cancer KRAS_G12V CREBBP 38 69 Primary -0.83 -2.94 0.54 1010.84 1.00 588 37 68 1 TRUE 0.46
colorectal cancer KRAS_G12V CREBBP 194 188 Tumor Type:overall -1.14 -2.91 0.39 1600.85 1.00 1889 187 181 7 TRUE 0.79
non-small cell lung cancer KRAS_G12V CREBBP 169 142 Tumor Type:overall 0.34 -0.91 1.66 1405.56 1.00 3388 160 133 9 TRUE 0.22
uterine cancer KRAS_G12V CREBBP 57 95 Tumor Type:overall -0.06 -2.27 1.91 1399.28 1.00 930 52 90 5 TRUE 0.02
non-small cell lung cancer KRAS_G12V BRIP1 50 30 Metastasis -1.54 -4.39 0.61 641.16 1.00 1303 49 29 1 TRUE 0.62
non-small cell lung cancer KRAS_G12V BRIP1 119 40 Primary -1.96 -5.34 0.03 699.13 1.00 2140 119 40 0 TRUE 0.78
non-small cell lung cancer KRAS_G12V BRIP1 169 70 Tumor Type:overall -1.74 -4.89 0.33 668.66 1.00 3443 168 69 1 TRUE 0.69
colorectal cancer KRAS_G12V AXIN2 73 26 Metastasis -1.85 -5.32 -0.15 1414.90 1.00 781 73 26 0 TRUE 0.74
colorectal cancer KRAS_G12V AXIN2 121 89 Primary -1.07 -2.23 -0.10 1406.52 1.00 1150 117 85 4 TRUE 1.28
non-small cell lung cancer KRAS_G12V AXIN2 50 26 Metastasis 0.87 -0.24 1.91 1111.70 1.00 1309 47 23 3 TRUE 0.93
non-small cell lung cancer KRAS_G12V AXIN2 119 36 Primary 0.66 -0.49 1.63 1148.56 1.00 2146 116 33 3 TRUE 0.68
uterine cancer KRAS_G12V AXIN2 18 15 Metastasis -0.48 -2.53 1.12 1323.74 1.00 347 17 14 1 TRUE 0.22
uterine cancer KRAS_G12V AXIN2 38 37 Primary -0.66 -2.63 0.78 1285.98 1.00 604 37 36 1 TRUE 0.35
colorectal cancer KRAS_G12V AXIN2 194 115 Tumor Type:overall -1.35 -3.56 0.39 1473.82 1.00 1931 190 111 4 TRUE 0.74
non-small cell lung cancer KRAS_G12V AXIN2 169 62 Tumor Type:overall 0.77 -0.54 1.97 1308.11 1.00 3455 163 56 6 TRUE 0.67
uterine cancer KRAS_G12V AXIN2 56 52 Tumor Type:overall -0.56 -2.61 1.02 1327.27 1.00 951 54 50 2 TRUE 0.27
colorectal cancer KRAS_G12V DOT1L 73 23 Metastasis -1.10 -2.83 0.29 1462.82 1.00 787 72 22 1 FALSE 0.79
colorectal cancer KRAS_G12V DOT1L 121 61 Primary -1.15 -2.63 -0.06 1424.46 1.00 1169 119 59 2 FALSE 1.09
non-small cell lung cancer KRAS_G12V DOT1L 50 46 Metastasis 0.38 -0.84 1.49 285.88 1.02 1291 46 42 4 FALSE 0.28
non-small cell lung cancer KRAS_G12V DOT1L 119 61 Primary -0.34 -2.21 0.82 29.53 1.10 2121 118 60 1 FALSE 0.17
colorectal cancer KRAS_G12V DOT1L 194 84 Tumor Type:overall -1.10 -2.79 0.34 1411.99 1.00 1956 191 81 3 FALSE 0.80
non-small cell lung cancer KRAS_G12V DOT1L 169 107 Tumor Type:overall 0.03 -1.61 1.48 104.20 1.04 3412 164 102 5 FALSE 0.02
colorectal cancer KRAS_G12V PTPRS 73 63 Metastasis -0.53 -1.44 0.38 1563.71 1.00 755 69 59 4 FALSE 0.59
colorectal cancer KRAS_G12V PTPRS 121 191 Primary -0.70 -1.35 -0.09 1383.05 1.00 1078 112 182 9 FALSE 1.52
non-small cell lung cancer KRAS_G12V PTPRS 50 32 Metastasis 0.27 -1.06 1.31 1157.25 1.00 1306 49 31 1 FALSE 0.19
non-small cell lung cancer KRAS_G12V PTPRS 119 48 Primary 0.50 -0.48 1.37 1105.27 1.00 2137 114 43 5 FALSE 0.54
uterine cancer KRAS_G12V PTPRS 19 23 Metastasis -0.32 -1.96 1.17 1051.10 1.00 342 17 21 2 FALSE 0.17
uterine cancer KRAS_G12V PTPRS 38 56 Primary -0.71 -2.46 0.53 827.89 1.00 593 37 55 1 FALSE 0.46
colorectal cancer KRAS_G12V PTPRS 194 254 Tumor Type:overall -0.64 -1.88 0.46 1498.07 1.00 1833 181 241 13 FALSE 0.54
non-small cell lung cancer KRAS_G12V PTPRS 169 80 Tumor Type:overall 0.39 -0.88 1.51 1212.74 1.00 3443 163 74 6 FALSE 0.28
uterine cancer KRAS_G12V PTPRS 57 79 Tumor Type:overall -0.52 -2.28 0.94 907.22 1.00 935 54 76 3 FALSE 0.28
colorectal cancer KRAS_G12V SMARCA4 73 40 Metastasis -2.44 -5.61 -0.72 1302.08 1.00 771 73 40 0 FALSE 1.22
colorectal cancer KRAS_G12V SMARCA4 121 129 Primary -1.79 -3.16 -0.73 1478.01 1.00 1125 118 126 3 FALSE 2.41
non-small cell lung cancer KRAS_G12V SMARCA4 50 149 Metastasis 0.93 0.19 1.61 1473.16 1.00 1206 37 136 13 FALSE 2.10
non-small cell lung cancer KRAS_G12V SMARCA4 119 164 Primary 0.08 -0.66 0.69 1502.95 1.00 2035 111 156 8 FALSE 0.09
uterine cancer KRAS_G12V SMARCA4 18 31 Metastasis -1.23 -3.21 0.36 1252.94 1.00 339 17 30 1 FALSE 0.74
uterine cancer KRAS_G12V SMARCA4 38 71 Primary -1.37 -3.45 0.00 1064.31 1.00 586 37 70 1 FALSE 0.94
colorectal cancer KRAS_G12V SMARCA4 194 169 Tumor Type:overall -2.05 -4.30 -0.18 1547.97 1.00 1896 191 166 3 FALSE 1.31
non-small cell lung cancer KRAS_G12V SMARCA4 169 313 Tumor Type:overall 0.51 -0.91 1.90 1513.13 1.00 3241 148 292 21 FALSE 0.33
uterine cancer KRAS_G12V SMARCA4 56 102 Tumor Type:overall -1.29 -3.22 0.24 1184.09 1.00 925 54 100 2 FALSE 0.81
colorectal cancer KRAS_G12V PTPRT 73 58 Metastasis -0.47 -1.34 0.26 1245.22 1.00 754 70 55 3 FALSE 0.59
colorectal cancer KRAS_G12V PTPRT 121 127 Primary -0.37 -1.07 0.26 1289.03 1.00 1118 112 118 9 FALSE 0.57
non-small cell lung cancer KRAS_G12V PTPRT 50 150 Metastasis -0.06 -0.88 0.59 1369.19 1.00 1217 45 145 5 FALSE 0.06
non-small cell lung cancer KRAS_G12V PTPRT 121 201 Primary 0.00 -0.59 0.55 1517.05 1.00 2019 110 190 11 FALSE 0.00
uterine cancer KRAS_G12V PTPRT 18 24 Metastasis -1.05 -3.00 0.54 1199.86 1.00 343 17 23 1 FALSE 0.63
uterine cancer KRAS_G12V PTPRT 38 63 Primary -1.24 -3.04 0.15 1186.46 1.00 588 37 62 1 FALSE 0.88
colorectal cancer KRAS_G12V PTPRT 194 185 Tumor Type:overall -0.42 -1.32 0.45 1393.53 1.00 1872 182 173 12 FALSE 0.44
non-small cell lung cancer KRAS_G12V PTPRT 171 351 Tumor Type:overall -0.04 -0.97 0.81 1284.33 1.00 3236 155 335 16 FALSE 0.03
uterine cancer KRAS_G12V PTPRT 56 87 Tumor Type:overall -1.14 -3.04 0.42 1329.80 1.00 931 54 85 2 FALSE 0.69
colorectal cancer KRAS_G12V HGF 73 22 Metastasis -2.01 -4.51 -0.06 463.70 1.00 784 72 21 1 FALSE 1.10
colorectal cancer KRAS_G12V HGF 121 34 Primary -2.25 -5.06 -0.46 559.19 1.01 1190 121 34 0 FALSE 1.18
non-small cell lung cancer KRAS_G12V HGF 50 72 Metastasis 0.18 -0.86 1.19 1395.74 1.00 1267 45 67 5 FALSE 0.13
non-small cell lung cancer KRAS_G12V HGF 119 119 Primary -0.70 -2.04 0.26 1183.88 1.00 2073 117 117 2 FALSE 0.64
colorectal cancer KRAS_G12V HGF 194 56 Tumor Type:overall -2.11 -4.77 -0.16 515.52 1.00 1974 193 55 1 FALSE 1.16
non-small cell lung cancer KRAS_G12V HGF 169 191 Tumor Type:overall -0.23 -1.72 1.22 1275.88 1.00 3340 162 184 7 FALSE 0.12
colorectal cancer KRAS_G12V BLM 73 14 Metastasis -2.00 -5.49 0.01 1122.07 1.00 795 73 14 0 TRUE 0.76
colorectal cancer KRAS_G12V BLM 121 56 Primary -1.43 -3.13 -0.15 1195.16 1.00 1170 119 54 2 TRUE 1.15
colorectal cancer KRAS_G12V BLM 194 70 Tumor Type:overall -1.61 -3.98 0.38 1444.51 1.00 1965 192 68 2 TRUE 0.78
colorectal cancer KRAS_G12V PIK3CA 83 151 Metastasis 0.62 0.14 1.12 1502.13 1.00 751 61 129 22 TRUE 1.86
colorectal cancer KRAS_G12V PIK3CA 137 360 Primary 0.28 -0.13 0.67 1504.61 1.00 1084 100 323 37 TRUE 0.79
non-small cell lung cancer KRAS_G12V PIK3CA 52 80 Metastasis -0.34 -1.36 0.62 351.54 1.01 1305 49 77 3 TRUE 0.28
non-small cell lung cancer KRAS_G12V PIK3CA 124 162 Primary -0.49 -1.38 0.34 188.31 1.02 2099 119 157 5 TRUE 0.58
uterine cancer KRAS_G12V PIK3CA 21 153 Metastasis 0.08 -0.60 0.83 1421.39 1.00 256 12 144 9 TRUE 0.08
uterine cancer KRAS_G12V PIK3CA 52 404 Primary -0.08 -0.62 0.45 1493.61 1.00 441 30 382 22 TRUE 0.12
colorectal cancer KRAS_G12V PIK3CA 220 511 Tumor Type:overall 0.44 -0.46 1.36 1583.64 1.00 1835 161 452 59 TRUE 0.47
non-small cell lung cancer KRAS_G12V PIK3CA 176 242 Tumor Type:overall -0.41 -1.50 0.56 281.99 1.01 3404 168 234 8 TRUE 0.33
uterine cancer KRAS_G12V PIK3CA 73 557 Tumor Type:overall 0.01 -0.87 0.97 1297.71 1.00 697 42 526 31 TRUE 0.00
non-small cell lung cancer KRAS_G12V GATA3 50 26 Metastasis -0.61 -2.51 0.87 1274.34 1.00 1308 49 25 1 FALSE 0.32
non-small cell lung cancer KRAS_G12V GATA3 119 40 Primary -0.76 -2.77 0.65 1220.29 1.00 2143 118 39 1 FALSE 0.43
non-small cell lung cancer KRAS_G12V GATA3 169 66 Tumor Type:overall -0.68 -2.58 0.76 1239.00 1.00 3451 167 64 2 FALSE 0.36
colorectal cancer KRAS_G12V ESR1 73 22 Metastasis -1.41 -3.32 0.17 1062.27 1.00 784 72 21 1 TRUE 0.97
colorectal cancer KRAS_G12V ESR1 121 50 Primary -1.52 -3.32 -0.19 888.36 1.00 1174 120 49 1 TRUE 1.20
non-small cell lung cancer KRAS_G12V ESR1 50 17 Metastasis -1.54 -5.00 0.51 764.65 1.00 1316 50 17 0 TRUE 0.54
non-small cell lung cancer KRAS_G12V ESR1 119 39 Primary -1.36 -4.02 0.42 729.70 1.00 2143 118 38 1 TRUE 0.63
colorectal cancer KRAS_G12V ESR1 194 72 Tumor Type:overall -1.45 -3.37 0.12 1170.59 1.00 1958 192 70 2 TRUE 0.97
non-small cell lung cancer KRAS_G12V ESR1 169 56 Tumor Type:overall -1.44 -4.44 0.55 938.05 1.00 3459 168 55 1 TRUE 0.56
colorectal cancer KRAS_G12V ALK 81 37 Metastasis -1.75 -3.93 -0.42 1258.39 1.00 836 81 37 0 TRUE 0.99
colorectal cancer KRAS_G12V ALK 135 78 Primary -1.38 -2.73 -0.26 872.64 1.00 1302 132 75 3 TRUE 1.56
non-small cell lung cancer KRAS_G12V ALK 52 67 Metastasis 0.20 -0.69 1.01 1454.67 1.00 1320 49 64 3 TRUE 0.19
non-small cell lung cancer KRAS_G12V ALK 124 102 Primary 0.24 -0.48 0.90 1343.92 1.00 2160 117 95 7 TRUE 0.30
uterine cancer KRAS_G12V ALK 19 15 Metastasis -5.01 -12.47 -0.78 361.02 1.01 368 19 15 0 TRUE 1.04
uterine cancer KRAS_G12V ALK 45 38 Primary -5.07 -12.38 -0.99 309.40 1.01 692 45 38 0 TRUE 1.07
colorectal cancer KRAS_G12V ALK 216 115 Tumor Type:overall -1.54 -3.26 -0.23 1188.34 1.00 2138 213 112 3 TRUE 1.26
non-small cell lung cancer KRAS_G12V ALK 176 169 Tumor Type:overall 0.22 -0.68 1.10 1299.20 1.00 3480 166 159 10 TRUE 0.19
uterine cancer KRAS_G12V ALK 64 53 Tumor Type:overall -4.99 -12.32 -0.83 350.24 1.01 1060 64 53 0 TRUE 1.08
colorectal cancer KRAS_G12V RNF43 73 64 Metastasis -2.07 -3.72 -0.72 1383.24 1.00 756 72 63 1 TRUE 2.28
colorectal cancer KRAS_G12V RNF43 121 203 Primary -2.07 -3.28 -1.09 1469.24 1.00 1074 118 200 3 TRUE 3.61
pancreatic cancer KRAS_G12V RNF43 126 28 Metastasis 0.19 -0.46 0.84 1423.76 1.00 434 119 21 7 TRUE 0.25
pancreatic cancer KRAS_G12V RNF43 250 52 Primary 0.23 -0.30 0.74 1427.50 1.00 612 233 35 17 TRUE 0.40
uterine cancer KRAS_G12V RNF43 19 22 Metastasis 0.04 -1.32 1.39 1472.16 1.00 340 17 20 2 TRUE 0.02
uterine cancer KRAS_G12V RNF43 39 73 Primary -0.25 -1.49 0.76 1520.09 1.00 580 36 70 3 TRUE 0.19
colorectal cancer KRAS_G12V RNF43 194 267 Tumor Type:overall -2.04 -3.63 -0.57 1413.30 1.00 1830 190 263 4 TRUE 2.04
pancreatic cancer KRAS_G12V RNF43 376 80 Tumor Type:overall 0.20 -0.68 0.97 1579.03 1.00 1046 352 56 24 TRUE 0.18
uterine cancer KRAS_G12V RNF43 58 95 Tumor Type:overall -0.13 -1.69 1.26 1492.99 1.00 920 53 90 5 TRUE 0.07
non-small cell lung cancer KRAS_G12V U2AF1 50 30 Metastasis 0.97 -0.04 1.83 1235.67 1.00 1306 47 27 3 FALSE 1.39
non-small cell lung cancer KRAS_G12V U2AF1 119 48 Primary 0.96 0.12 1.72 1469.25 1.00 2138 113 42 6 FALSE 1.77
non-small cell lung cancer KRAS_G12V U2AF1 169 78 Tumor Type:overall 0.95 -0.11 1.86 1453.86 1.00 3444 160 69 9 FALSE 1.07
colorectal cancer KRAS_G12V LATS1 73 15 Metastasis -2.31 -5.88 -0.23 1075.84 1.00 791 73 15 0 FALSE 0.95
colorectal cancer KRAS_G12V LATS1 121 40 Primary -2.05 -4.71 -0.24 762.71 1.00 1186 120 39 1 FALSE 1.17
non-small cell lung cancer KRAS_G12V LATS1 50 28 Metastasis 0.00 -1.57 1.38 1536.75 1.00 1306 48 26 2 FALSE 0.00
non-small cell lung cancer KRAS_G12V LATS1 119 40 Primary -0.35 -1.95 0.85 1434.15 1.00 2141 118 39 1 FALSE 0.20
colorectal cancer KRAS_G12V LATS1 194 55 Tumor Type:overall -2.16 -5.30 -0.14 935.29 1.00 1977 193 54 1 FALSE 1.03
non-small cell lung cancer KRAS_G12V LATS1 169 68 Tumor Type:overall -0.18 -1.87 1.28 1488.80 1.00 3447 166 65 3 FALSE 0.08
colorectal cancer KRAS_G12V LATS2 73 27 Metastasis -6.23 -13.56 -1.64 77.60 1.03 778 73 27 0 FALSE 1.50
colorectal cancer KRAS_G12V LATS2 121 43 Primary -6.23 -13.20 -1.68 72.92 1.03 1180 121 43 0 FALSE 1.52
non-small cell lung cancer KRAS_G12V LATS2 50 23 Metastasis 0.12 -1.41 1.45 1386.74 1.00 1311 48 21 2 FALSE 0.06
non-small cell lung cancer KRAS_G12V LATS2 119 38 Primary -0.26 -1.86 0.95 1379.19 1.00 2145 118 37 1 FALSE 0.14
uterine cancer KRAS_G12V LATS2 18 15 Metastasis -1.69 -4.77 0.28 850.16 1.00 347 18 15 0 FALSE 0.71
uterine cancer KRAS_G12V LATS2 38 39 Primary -1.50 -4.14 0.22 763.76 1.00 605 37 38 1 FALSE 0.75
colorectal cancer KRAS_G12V LATS2 194 70 Tumor Type:overall -6.21 -13.26 -1.67 70.83 1.03 1958 194 70 0 FALSE 1.51
non-small cell lung cancer KRAS_G12V LATS2 169 61 Tumor Type:overall -0.06 -1.68 1.29 1279.38 1.00 3456 166 58 3 FALSE 0.03
uterine cancer KRAS_G12V LATS2 56 54 Tumor Type:overall -1.56 -4.53 0.37 768.21 1.00 952 55 53 1 FALSE 0.68
colorectal cancer KRAS_G12V PTEN 81 43 Metastasis -0.43 -1.49 0.44 1510.24 1.00 838 78 40 3 TRUE 0.42
colorectal cancer KRAS_G12V PTEN 135 142 Primary -0.53 -1.24 0.14 1131.68 1.00 1268 127 134 8 TRUE 0.87
non-small cell lung cancer KRAS_G12V PTEN 52 51 Metastasis -5.60 -12.80 -1.37 993.51 1.00 1330 52 51 0 TRUE 1.26
non-small cell lung cancer KRAS_G12V PTEN 124 85 Primary -5.63 -12.57 -1.57 1085.62 1.00 2169 124 85 0 TRUE 1.28
uterine cancer KRAS_G12V PTEN 21 160 Metastasis -0.16 -1.05 0.57 1670.79 1.00 278 15 154 6 TRUE 0.15
uterine cancer KRAS_G12V PTEN 58 467 Primary 0.26 -0.23 0.78 1527.97 1.00 453 25 434 33 TRUE 0.50
colorectal cancer KRAS_G12V PTEN 216 185 Tumor Type:overall -0.50 -1.79 0.66 1626.35 1.00 2106 205 174 11 TRUE 0.36
non-small cell lung cancer KRAS_G12V PTEN 176 136 Tumor Type:overall -5.58 -12.65 -1.54 1016.42 1.00 3499 176 136 0 TRUE 1.29
uterine cancer KRAS_G12V PTEN 79 627 Tumor Type:overall 0.05 -1.05 1.18 1567.89 1.00 731 40 588 39 TRUE 0.03
colorectal cancer KRAS_G12V BCOR 73 18 Metastasis -0.33 -1.91 1.10 1510.21 1.00 790 71 16 2 FALSE 0.17
colorectal cancer KRAS_G12V BCOR 121 94 Primary -1.07 -2.29 -0.10 1566.72 1.00 1145 118 91 3 FALSE 1.32
non-small cell lung cancer KRAS_G12V BCOR 50 54 Metastasis 0.82 -0.01 1.59 1049.40 1.00 1286 46 50 4 FALSE 1.39
non-small cell lung cancer KRAS_G12V BCOR 120 80 Primary 0.91 0.28 1.58 549.21 1.00 2115 110 70 10 FALSE 2.21
uterine cancer KRAS_G12V BCOR 18 45 Metastasis -0.85 -2.23 0.25 1238.63 1.00 323 17 44 1 FALSE 0.74
uterine cancer KRAS_G12V BCOR 38 95 Primary -0.81 -2.03 0.19 1123.02 1.00 561 35 92 3 FALSE 0.82
colorectal cancer KRAS_G12V BCOR 194 112 Tumor Type:overall -0.68 -2.47 1.19 1523.63 1.00 1935 189 107 5 FALSE 0.32
non-small cell lung cancer KRAS_G12V BCOR 170 134 Tumor Type:overall 0.87 -0.03 1.72 1216.27 1.00 3401 156 120 14 FALSE 1.28
uterine cancer KRAS_G12V BCOR 56 140 Tumor Type:overall -0.83 -2.23 0.28 1124.22 1.00 884 52 136 4 FALSE 0.67
colorectal cancer KRAS_G12V CTNNB1 81 44 Metastasis -0.25 -1.16 0.55 1418.54 1.00 832 78 41 3 TRUE 0.24
colorectal cancer KRAS_G12V CTNNB1 136 119 Primary -0.15 -0.81 0.43 1354.71 1.00 1259 126 109 10 TRUE 0.20
non-small cell lung cancer KRAS_G12V CTNNB1 52 55 Metastasis -1.67 -4.40 -0.02 1248.17 1.00 1325 52 55 0 TRUE 0.82
non-small cell lung cancer KRAS_G12V CTNNB1 124 66 Primary -1.18 -3.03 0.10 1426.60 1.00 2187 122 64 2 TRUE 0.86
uterine cancer KRAS_G12V CTNNB1 19 64 Metastasis -1.04 -2.69 0.13 1239.76 1.00 317 18 63 1 TRUE 0.80
uterine cancer KRAS_G12V CTNNB1 45 79 Primary -0.78 -1.99 0.28 1374.48 1.00 649 42 76 3 TRUE 0.73
colorectal cancer KRAS_G12V CTNNB1 217 163 Tumor Type:overall -0.19 -1.18 0.77 1458.84 1.00 2091 204 150 13 TRUE 0.14
non-small cell lung cancer KRAS_G12V CTNNB1 176 121 Tumor Type:overall -1.41 -3.73 0.19 1345.09 1.00 3512 174 119 2 TRUE 0.78
uterine cancer KRAS_G12V CTNNB1 64 143 Tumor Type:overall -0.89 -2.60 0.52 1332.41 1.00 966 60 139 4 TRUE 0.59
cancer of unknown primary KRAS_G12V ARID1A 48 109 Metastasis 0.24 -0.53 0.94 1373.78 1.00 573 39 100 9 TRUE 0.28
colorectal cancer KRAS_G12V ARID1A 73 73 Metastasis -1.05 -2.43 -0.11 1303.55 1.00 756 71 71 2 TRUE 1.14
colorectal cancer KRAS_G12V ARID1A 122 242 Primary -0.57 -1.12 -0.03 1562.07 1.00 1064 108 228 14 TRUE 1.38
non-small cell lung cancer KRAS_G12V ARID1A 52 129 Metastasis 0.44 -0.39 1.18 1319.35 1.00 1224 43 120 9 TRUE 0.56
non-small cell lung cancer KRAS_G12V ARID1A 119 155 Primary -0.48 -1.54 0.32 1487.20 1.00 2039 115 151 4 TRUE 0.53
pancreatic cancer KRAS_G12V ARID1A 126 58 Metastasis -0.04 -0.59 0.60 541.86 1.00 413 112 44 14 TRUE 0.05
pancreatic cancer KRAS_G12V ARID1A 250 69 Primary -0.34 -0.90 0.17 1489.09 1.00 594 236 55 14 TRUE 0.69
uterine cancer KRAS_G12V ARID1A 22 153 Metastasis 0.76 0.10 1.47 1503.87 1.00 267 10 141 12 TRUE 1.52
uterine cancer KRAS_G12V ARID1A 46 374 Primary 0.74 0.20 1.28 1256.65 1.00 410 17 345 29 TRUE 2.05
cancer of unknown primary KRAS_G12V ARID1A 48 109 Tumor Type:overall 0.23 -3.95 4.35 1503.46 1.00 573 39 100 9 TRUE 0.04
colorectal cancer KRAS_G12V ARID1A 195 315 Tumor Type:overall -0.76 -2.16 0.65 1355.39 1.00 1820 179 299 16 TRUE 0.54
non-small cell lung cancer KRAS_G12V ARID1A 171 284 Tumor Type:overall -0.03 -1.54 1.41 1414.20 1.00 3263 158 271 13 TRUE 0.02
pancreatic cancer KRAS_G12V ARID1A 376 127 Tumor Type:overall -0.21 -1.05 0.66 1503.92 1.00 1007 348 99 28 TRUE 0.21
uterine cancer KRAS_G12V ARID1A 68 527 Tumor Type:overall 0.73 -0.12 1.71 1480.20 1.00 677 27 486 41 TRUE 0.85
colorectal cancer KRAS_G12V PIK3R1 73 27 Metastasis -0.71 -2.32 0.45 1389.62 1.00 784 72 26 1 TRUE 0.50
colorectal cancer KRAS_G12V PIK3R1 121 89 Primary -0.44 -1.38 0.35 1344.49 1.00 1150 115 83 6 TRUE 0.52
non-small cell lung cancer KRAS_G12V PIK3R1 50 12 Metastasis -0.60 -4.00 1.19 1277.44 1.00 1321 50 12 0 TRUE 0.17
non-small cell lung cancer KRAS_G12V PIK3R1 119 43 Primary 0.01 -1.50 1.15 1550.88 1.00 2140 116 40 3 TRUE 0.00
uterine cancer KRAS_G12V PIK3R1 18 81 Metastasis -0.34 -1.41 0.49 36.03 1.06 294 16 79 2 TRUE 0.32
uterine cancer KRAS_G12V PIK3R1 40 187 Primary -0.15 -0.90 0.49 43.75 1.05 497 30 177 10 TRUE 0.17
colorectal cancer KRAS_G12V PIK3R1 194 116 Tumor Type:overall -0.55 -2.16 0.87 1415.51 1.00 1934 187 109 7 TRUE 0.34
non-small cell lung cancer KRAS_G12V PIK3R1 169 55 Tumor Type:overall -0.27 -2.83 1.50 1440.88 1.00 3461 166 52 3 TRUE 0.09
uterine cancer KRAS_G12V PIK3R1 58 268 Tumor Type:overall -0.24 -1.34 0.62 134.41 1.03 791 46 256 12 TRUE 0.18
colorectal cancer KRAS_G12V IKZF1 73 24 Metastasis -2.22 -4.96 -0.25 1502.30 1.00 784 72 23 1 TRUE 1.15
colorectal cancer KRAS_G12V IKZF1 121 62 Primary -2.82 -6.08 -0.85 1390.43 1.00 1161 121 62 0 TRUE 1.31
non-small cell lung cancer KRAS_G12V IKZF1 50 36 Metastasis -2.11 -5.96 0.04 737.09 1.00 1296 50 36 0 TRUE 0.78
non-small cell lung cancer KRAS_G12V IKZF1 119 46 Primary -1.79 -5.08 0.09 573.37 1.00 2136 118 45 1 TRUE 0.79
colorectal cancer KRAS_G12V IKZF1 194 86 Tumor Type:overall -2.48 -5.36 -0.37 1468.59 1.00 1945 193 85 1 TRUE 1.24
non-small cell lung cancer KRAS_G12V IKZF1 169 82 Tumor Type:overall -1.92 -5.46 0.23 713.91 1.00 3432 168 81 1 TRUE 0.78
colorectal cancer KRAS_G12V TERT 74 27 Metastasis -0.58 -1.82 0.53 1308.43 1.00 783 72 25 2 TRUE 0.49
colorectal cancer KRAS_G12V TERT 121 71 Primary -0.71 -1.87 0.17 777.90 1.00 1159 118 68 3 TRUE 0.75
non-small cell lung cancer KRAS_G12V TERT 50 61 Metastasis -0.66 -1.91 0.38 1407.88 1.00 1277 49 60 1 TRUE 0.59
non-small cell lung cancer KRAS_G12V TERT 119 105 Primary -0.56 -1.60 0.36 1479.62 1.00 2082 115 101 4 TRUE 0.60
uterine cancer KRAS_G12V TERT 18 19 Metastasis -1.49 -4.17 0.55 686.35 1.00 342 17 18 1 TRUE 0.76
uterine cancer KRAS_G12V TERT 38 46 Primary -1.87 -4.82 -0.07 529.55 1.01 591 38 46 0 TRUE 0.89
colorectal cancer KRAS_G12V TERT 195 98 Tumor Type:overall -0.63 -2.02 0.53 1312.85 1.00 1942 190 93 5 TRUE 0.49
non-small cell lung cancer KRAS_G12V TERT 169 166 Tumor Type:overall -0.60 -1.84 0.54 1446.72 1.00 3359 164 161 5 TRUE 0.48
uterine cancer KRAS_G12V TERT 56 65 Tumor Type:overall -1.68 -4.58 0.18 737.47 1.00 933 55 64 1 TRUE 0.85
colorectal cancer KRAS_G12V FAT1 73 62 Metastasis -1.59 -3.16 -0.45 1004.65 1.00 765 72 61 1 FALSE 1.69
colorectal cancer KRAS_G12V FAT1 121 165 Primary -1.35 -2.33 -0.54 1147.47 1.00 1115 116 160 5 FALSE 2.51
non-small cell lung cancer KRAS_G12V FAT1 50 123 Metastasis -0.25 -1.12 0.62 1339.17 1.00 1221 45 118 5 FALSE 0.24
non-small cell lung cancer KRAS_G12V FAT1 119 182 Primary -0.53 -1.35 0.16 1437.15 1.00 2027 114 177 5 FALSE 0.74
uterine cancer KRAS_G12V FAT1 19 51 Metastasis -0.21 -1.34 0.77 1274.24 1.00 331 16 48 3 FALSE 0.15
uterine cancer KRAS_G12V FAT1 38 132 Primary -0.47 -1.40 0.37 694.25 1.01 568 34 128 4 FALSE 0.51
colorectal cancer KRAS_G12V FAT1 194 227 Tumor Type:overall -1.44 -2.93 -0.25 1195.03 1.00 1880 188 221 6 FALSE 1.48
non-small cell lung cancer KRAS_G12V FAT1 169 305 Tumor Type:overall -0.36 -1.38 0.75 1290.23 1.00 3248 159 295 10 FALSE 0.26
uterine cancer KRAS_G12V FAT1 57 183 Tumor Type:overall -0.34 -1.59 0.82 1057.08 1.01 899 50 176 7 FALSE 0.24
colorectal cancer KRAS_G12V FGFR4 121 46 Primary -6.23 -15.50 -1.25 1122.90 1.00 1179 121 46 0 TRUE 0.69
colorectal cancer KRAS_G12V FGFR4 121 46 Tumor Type:overall -4.51 -12.05 2.26 1134.64 1.00 1179 121 46 0 TRUE 0.69
colorectal cancer KRAS_G12V CIC 73 37 Metastasis -0.90 -2.54 0.11 1114.13 1.00 775 72 36 1 TRUE 0.75
colorectal cancer KRAS_G12V CIC 121 100 Primary -0.59 -1.46 0.22 1601.61 1.00 1149 115 94 6 TRUE 0.79
non-small cell lung cancer KRAS_G12V CIC 50 53 Metastasis -0.64 -2.37 0.66 1502.72 1.00 1289 49 52 1 TRUE 0.38
non-small cell lung cancer KRAS_G12V CIC 119 39 Primary -0.38 -2.00 0.83 1713.10 1.00 2145 117 37 2 TRUE 0.22
uterine cancer KRAS_G12V CIC 18 20 Metastasis 0.23 -1.26 1.27 1474.71 1.00 342 17 19 1 TRUE 0.14
uterine cancer KRAS_G12V CIC 39 55 Primary 0.40 -0.57 1.26 1395.92 1.00 601 34 50 5 TRUE 0.40
colorectal cancer KRAS_G12V CIC 194 137 Tumor Type:overall -0.74 -2.21 0.42 1250.10 1.00 1924 187 130 7 TRUE 0.53
non-small cell lung cancer KRAS_G12V CIC 169 92 Tumor Type:overall -0.49 -2.46 1.29 1527.14 1.00 3434 166 89 3 TRUE 0.21
uterine cancer KRAS_G12V CIC 57 75 Tumor Type:overall 0.30 -1.13 1.51 1437.36 1.00 943 51 69 6 TRUE 0.18
colorectal cancer KRAS_G12V KDM6A 73 13 Metastasis -0.91 -5.08 0.79 1413.88 1.00 793 73 13 0 FALSE 0.25
colorectal cancer KRAS_G12V KDM6A 121 49 Primary 0.34 -0.60 1.17 1336.58 1.00 1181 114 42 7 FALSE 0.34
non-small cell lung cancer KRAS_G12V KDM6A 50 23 Metastasis -0.89 -3.75 0.70 1013.88 1.00 1310 50 23 0 FALSE 0.37
non-small cell lung cancer KRAS_G12V KDM6A 119 38 Primary -0.51 -2.31 0.87 1326.86 1.00 2146 117 36 2 FALSE 0.28
pancreatic cancer KRAS_G12V KDM6A 126 24 Metastasis 0.27 -0.50 0.98 1442.52 1.00 436 120 18 6 FALSE 0.32
pancreatic cancer KRAS_G12V KDM6A 249 35 Primary 0.36 -0.27 0.95 1245.92 1.00 623 236 22 13 FALSE 0.60
uterine cancer KRAS_G12V KDM6A 18 16 Metastasis -1.24 -4.01 0.77 833.55 1.00 344 17 15 1 FALSE 0.51
uterine cancer KRAS_G12V KDM6A 38 38 Primary -1.70 -5.05 0.30 617.16 1.01 605 38 38 0 FALSE 0.66
colorectal cancer KRAS_G12V KDM6A 194 62 Tumor Type:overall -0.25 -3.00 1.58 1268.67 1.00 1974 187 55 7 FALSE 0.08
non-small cell lung cancer KRAS_G12V KDM6A 169 61 Tumor Type:overall -0.69 -2.94 0.90 1170.54 1.00 3456 167 59 2 FALSE 0.31
pancreatic cancer KRAS_G12V KDM6A 375 59 Tumor Type:overall 0.30 -0.64 1.19 1457.96 1.00 1059 356 40 19 FALSE 0.29
uterine cancer KRAS_G12V KDM6A 56 54 Tumor Type:overall -1.45 -4.48 0.67 785.20 1.00 949 55 53 1 FALSE 0.55
colorectal cancer KRAS_G12V NCOR1 73 37 Metastasis -1.66 -6.06 0.00 1261.45 1.00 772 73 37 0 FALSE 0.53
colorectal cancer KRAS_G12V NCOR1 124 98 Primary -0.36 -1.14 0.40 1061.91 1.00 1149 116 90 8 FALSE 0.45
non-small cell lung cancer KRAS_G12V NCOR1 50 52 Metastasis -2.20 -5.37 -0.10 1386.15 1.00 1288 50 52 0 FALSE 1.02
non-small cell lung cancer KRAS_G12V NCOR1 119 52 Primary -1.94 -4.60 -0.12 1411.64 1.00 2130 118 51 1 FALSE 1.09
uterine cancer KRAS_G12V NCOR1 18 23 Metastasis -5.42 -12.10 -1.08 1185.95 1.00 344 18 23 0 FALSE 1.21
uterine cancer KRAS_G12V NCOR1 38 67 Primary -5.50 -12.18 -1.26 1129.27 1.00 594 38 67 0 FALSE 1.23
colorectal cancer KRAS_G12V NCOR1 197 135 Tumor Type:overall -0.95 -3.72 0.61 1492.10 1.00 1921 189 127 8 FALSE 0.42
non-small cell lung cancer KRAS_G12V NCOR1 169 104 Tumor Type:overall -2.03 -5.02 0.06 1343.08 1.00 3418 168 103 1 FALSE 0.97
uterine cancer KRAS_G12V NCOR1 56 90 Tumor Type:overall -5.38 -11.94 -1.03 1074.51 1.00 938 56 90 0 FALSE 1.22
colorectal cancer KRAS_G12V POLE 73 28 Metastasis -2.36 -5.65 -0.43 1518.89 1.00 778 73 28 0 TRUE 1.08
colorectal cancer KRAS_G12V POLE 121 113 Primary -1.64 -3.03 -0.50 1497.63 1.00 1137 118 110 3 TRUE 1.99
non-small cell lung cancer KRAS_G12V POLE 50 59 Metastasis 0.62 -0.30 1.47 1361.00 1.00 1280 45 54 5 TRUE 0.78
non-small cell lung cancer KRAS_G12V POLE 120 77 Primary 0.36 -0.48 1.06 1376.26 1.00 2113 115 72 5 TRUE 0.42
uterine cancer KRAS_G12V POLE 18 27 Metastasis -2.45 -5.69 -0.11 1247.48 1.00 340 18 27 0 TRUE 1.07
uterine cancer KRAS_G12V POLE 38 84 Primary -2.23 -4.98 -0.45 1223.86 1.00 587 37 83 1 TRUE 1.31
colorectal cancer KRAS_G12V POLE 194 141 Tumor Type:overall -1.96 -4.36 -0.05 1380.17 1.00 1915 191 138 3 TRUE 1.12
non-small cell lung cancer KRAS_G12V POLE 170 136 Tumor Type:overall 0.51 -0.56 1.52 1557.76 1.00 3393 160 126 10 TRUE 0.46
uterine cancer KRAS_G12V POLE 56 111 Tumor Type:overall -2.31 -5.20 -0.18 1321.18 1.00 927 55 110 1 TRUE 1.13
non-small cell lung cancer KRAS_G12V CUL3 50 26 Metastasis -0.02 -1.53 1.20 1483.71 1.00 1308 49 25 1 FALSE 0.01
non-small cell lung cancer KRAS_G12V CUL3 120 51 Primary 0.02 -1.18 0.95 1451.58 1.00 2137 117 48 3 FALSE 0.01
non-small cell lung cancer KRAS_G12V CUL3 170 77 Tumor Type:overall 0.00 -1.46 1.22 1500.79 1.00 3445 166 73 4 FALSE 0.00
colorectal cancer KRAS_G12V ABL1 81 17 Metastasis -0.69 -2.22 0.54 1505.86 1.00 858 80 16 1 TRUE 0.48
colorectal cancer KRAS_G12V ABL1 136 56 Primary -0.67 -2.00 0.30 1502.39 1.00 1315 133 53 3 TRUE 0.61
colorectal cancer KRAS_G12V ABL1 217 73 Tumor Type:overall -0.68 -2.31 0.65 1587.71 1.00 2173 213 69 4 TRUE 0.41
colorectal cancer KRAS_G12V FOXP1 73 15 Metastasis -1.55 -4.89 0.32 1143.89 1.00 790 73 15 0 FALSE 0.59
colorectal cancer KRAS_G12V FOXP1 121 55 Primary -0.91 -2.44 0.21 1369.67 1.00 1173 118 52 3 FALSE 0.77
colorectal cancer KRAS_G12V FOXP1 194 70 Tumor Type:overall -1.21 -3.50 0.48 1691.70 1.00 1963 191 67 3 FALSE 0.60
colorectal cancer KRAS_G12V NOTCH2 73 18 Metastasis -2.62 -6.19 -0.45 1299.33 1.00 789 73 18 0 TRUE 1.09
colorectal cancer KRAS_G12V NOTCH2 121 55 Primary -2.32 -5.01 -0.50 1005.62 1.00 1173 120 54 1 TRUE 1.31
non-small cell lung cancer KRAS_G12V NOTCH2 50 40 Metastasis -0.77 -4.19 0.64 1191.47 1.00 1296 50 40 0 TRUE 0.28
non-small cell lung cancer KRAS_G12V NOTCH2 119 75 Primary -0.06 -1.11 0.86 1140.48 1.00 2116 114 70 5 TRUE 0.04
uterine cancer KRAS_G12V NOTCH2 18 13 Metastasis -6.12 -10.17 -0.96 3.23 1.37 346 18 13 0 TRUE 1.53
uterine cancer KRAS_G12V NOTCH2 38 41 Primary -6.18 -10.39 -1.24 3.33 1.36 603 38 41 0 TRUE 1.60
colorectal cancer KRAS_G12V NOTCH2 194 73 Tumor Type:overall -2.43 -5.46 -0.30 1022.46 1.00 1962 193 72 1 TRUE 1.15
non-small cell lung cancer KRAS_G12V NOTCH2 169 115 Tumor Type:overall -0.38 -2.42 1.06 1356.79 1.00 3412 164 110 5 TRUE 0.16
uterine cancer KRAS_G12V NOTCH2 56 54 Tumor Type:overall -6.09 -10.08 -1.11 NA 1.38 949 56 54 0 TRUE 1.54
non-small cell lung cancer KRAS_G12V DDR2 50 45 Metastasis 0.35 -0.79 1.35 1400.33 1.00 1290 47 42 3 TRUE 0.28
non-small cell lung cancer KRAS_G12V DDR2 119 53 Primary 0.15 -0.94 1.02 1518.48 1.00 2129 116 50 3 TRUE 0.12
uterine cancer KRAS_G12V DDR2 18 11 Metastasis -5.29 -12.45 -0.50 1364.96 1.00 352 18 11 0 TRUE 1.02
uterine cancer KRAS_G12V DDR2 38 46 Primary -5.40 -12.61 -0.83 927.33 1.01 601 38 46 0 TRUE 1.09
non-small cell lung cancer KRAS_G12V DDR2 169 98 Tumor Type:overall 0.23 -1.07 1.32 1498.01 1.00 3419 163 92 6 TRUE 0.15
uterine cancer KRAS_G12V DDR2 56 57 Tumor Type:overall -5.19 -12.03 -0.56 699.69 1.01 953 56 57 0 TRUE 1.04
colorectal cancer KRAS_G12V TGFBR2 73 26 Metastasis -0.53 -1.90 0.71 1415.06 1.00 781 71 24 2 TRUE 0.38
colorectal cancer KRAS_G12V TGFBR2 122 88 Primary -0.76 -1.82 0.08 1416.72 1.00 1141 118 84 4 TRUE 0.96
non-small cell lung cancer KRAS_G12V TGFBR2 50 27 Metastasis -0.89 -3.72 0.82 1168.34 1.00 1307 50 27 0 TRUE 0.33
non-small cell lung cancer KRAS_G12V TGFBR2 119 29 Primary -0.35 -2.13 1.02 1327.93 1.00 2154 117 27 2 TRUE 0.17
colorectal cancer KRAS_G12V TGFBR2 195 114 Tumor Type:overall -0.64 -2.14 0.65 1428.06 1.00 1922 189 108 6 TRUE 0.43
non-small cell lung cancer KRAS_G12V TGFBR2 169 56 Tumor Type:overall -0.60 -2.89 1.08 1384.64 1.00 3461 167 54 2 TRUE 0.25
colorectal cancer KRAS_G12V SMO 81 19 Metastasis -0.28 -1.52 0.87 1154.83 1.00 855 79 17 2 TRUE 0.19
colorectal cancer KRAS_G12V SMO 135 52 Primary -0.43 -1.55 0.58 1438.12 1.00 1320 132 49 3 TRUE 0.38
non-small cell lung cancer KRAS_G12V SMO 52 29 Metastasis -0.73 -2.75 0.79 1374.07 1.00 1352 51 28 1 TRUE 0.38
non-small cell lung cancer KRAS_G12V SMO 124 46 Primary -0.86 -2.71 0.47 1337.17 1.00 2206 123 45 1 TRUE 0.52
uterine cancer KRAS_G12V SMO 19 19 Metastasis -4.74 -11.48 -0.83 352.97 1.00 363 19 19 0 TRUE 0.97
uterine cancer KRAS_G12V SMO 45 33 Primary -4.74 -11.59 -0.85 302.61 1.00 693 45 33 0 TRUE 1.00
colorectal cancer KRAS_G12V SMO 216 71 Tumor Type:overall -0.37 -1.73 0.90 1449.24 1.00 2175 211 66 5 TRUE 0.24
non-small cell lung cancer KRAS_G12V SMO 176 75 Tumor Type:overall -0.80 -2.77 0.77 1396.33 1.00 3558 174 73 2 TRUE 0.41
uterine cancer KRAS_G12V SMO 64 52 Tumor Type:overall -4.69 -11.14 -0.85 298.96 1.00 1056 64 52 0 TRUE 1.00
colorectal cancer KRAS_G12V RPS6KA4 121 53 Primary -2.11 -5.07 -0.32 1478.22 1.00 1171 120 52 1 FALSE 1.08
colorectal cancer KRAS_G12V RPS6KA4 121 53 Tumor Type:overall -1.74 -5.85 3.36 1515.45 1.00 1171 120 52 1 FALSE 0.37
colorectal cancer KRAS_G12V KMT2A 73 37 Metastasis -1.46 -3.28 -0.13 1281.51 1.00 776 72 36 1 FALSE 1.24
colorectal cancer KRAS_G12V KMT2A 121 111 Primary -1.41 -2.68 -0.36 1136.05 1.00 1139 118 108 3 FALSE 1.80
non-small cell lung cancer KRAS_G12V KMT2A 50 53 Metastasis 0.01 -1.18 1.00 1298.25 1.00 1285 48 51 2 FALSE 0.01
non-small cell lung cancer KRAS_G12V KMT2A 119 61 Primary 0.09 -0.91 0.95 1277.58 1.00 2125 115 57 4 FALSE 0.07
uterine cancer KRAS_G12V KMT2A 18 30 Metastasis -0.82 -2.70 1.07 1199.25 1.00 338 16 28 2 FALSE 0.44
uterine cancer KRAS_G12V KMT2A 38 79 Primary -2.00 -6.01 -0.32 208.88 1.01 593 38 79 0 FALSE 0.73
colorectal cancer KRAS_G12V KMT2A 194 148 Tumor Type:overall -1.42 -3.21 0.14 1340.47 1.00 1915 190 144 4 FALSE 1.03
non-small cell lung cancer KRAS_G12V KMT2A 169 114 Tumor Type:overall 0.05 -1.18 1.17 1217.63 1.00 3410 163 108 6 FALSE 0.03
uterine cancer KRAS_G12V KMT2A 56 109 Tumor Type:overall -1.33 -3.86 0.70 1515.90 1.00 931 54 107 2 FALSE 0.61
colorectal cancer KRAS_G12V JAK3 81 22 Metastasis -2.10 -4.73 -0.25 621.37 1.00 853 80 21 1 TRUE 1.15
colorectal cancer KRAS_G12V JAK3 135 41 Primary -2.38 -5.56 -0.53 643.73 1.00 1324 135 41 0 TRUE 1.19
non-small cell lung cancer KRAS_G12V JAK3 52 23 Metastasis 0.74 -0.48 2.03 1585.71 1.00 1360 49 20 3 TRUE 0.62
non-small cell lung cancer KRAS_G12V JAK3 125 60 Primary 0.17 -1.02 1.08 1449.93 1.00 2193 122 57 3 TRUE 0.12
colorectal cancer KRAS_G12V JAK3 216 63 Tumor Type:overall -2.23 -5.02 -0.38 633.31 1.00 2177 215 62 1 TRUE 1.20
non-small cell lung cancer KRAS_G12V JAK3 177 83 Tumor Type:overall 0.43 -1.02 1.78 1204.30 1.00 3553 171 77 6 TRUE 0.26
non-small cell lung cancer KRAS_G12V PAK7 50 61 Metastasis 0.86 0.02 1.63 1467.11 1.00 1281 44 55 6 FALSE 1.44
non-small cell lung cancer KRAS_G12V PAK7 119 72 Primary 0.47 -0.41 1.19 1024.38 1.00 2118 114 67 5 FALSE 0.62
non-small cell lung cancer KRAS_G12V PAK7 169 133 Tumor Type:overall 0.66 -0.45 1.72 1364.15 1.00 3399 158 122 11 FALSE 0.64
non-small cell lung cancer KRAS_G12V STAG2 51 43 Metastasis 0.76 -0.41 1.89 1049.99 1.00 1297 46 38 5 TRUE 0.68
non-small cell lung cancer KRAS_G12V STAG2 119 59 Primary -0.46 -2.45 0.76 1321.62 1.00 2123 118 58 1 TRUE 0.23
uterine cancer KRAS_G12V STAG2 18 29 Metastasis -2.20 -5.13 -0.17 816.01 1.00 345 18 29 0 TRUE 0.96
uterine cancer KRAS_G12V STAG2 38 56 Primary -2.02 -4.42 -0.16 743.09 1.01 596 37 55 1 TRUE 1.08
non-small cell lung cancer KRAS_G12V STAG2 170 102 Tumor Type:overall 0.16 -1.75 1.80 1242.93 1.00 3420 164 96 6 TRUE 0.07
uterine cancer KRAS_G12V STAG2 56 85 Tumor Type:overall -2.10 -4.67 -0.12 769.54 1.01 941 55 84 1 TRUE 1.08
colorectal cancer KRAS_G12V BRCA2 73 48 Metastasis -0.82 -2.01 0.30 1475.23 1.00 770 70 45 3 TRUE 0.79
colorectal cancer KRAS_G12V BRCA2 121 142 Primary -1.39 -2.59 -0.50 1122.72 1.00 1134 118 139 3 TRUE 2.08
non-small cell lung cancer KRAS_G12V BRCA2 51 67 Metastasis -0.34 -1.60 0.70 1388.22 1.00 1274 49 65 2 TRUE 0.24
non-small cell lung cancer KRAS_G12V BRCA2 119 68 Primary -0.29 -1.51 0.62 1319.39 1.00 2118 116 65 3 TRUE 0.23
uterine cancer KRAS_G12V BRCA2 18 34 Metastasis -2.09 -4.83 0.20 1277.83 1.00 338 17 33 1 TRUE 0.98
uterine cancer KRAS_G12V BRCA2 38 100 Primary -2.87 -6.17 -0.84 1330.41 1.00 580 38 100 0 TRUE 1.25
colorectal cancer KRAS_G12V BRCA2 194 190 Tumor Type:overall -1.11 -2.62 0.44 1461.34 1.00 1904 188 184 6 TRUE 0.87
non-small cell lung cancer KRAS_G12V BRCA2 170 135 Tumor Type:overall -0.32 -1.85 0.94 1471.99 1.00 3392 165 130 5 TRUE 0.19
uterine cancer KRAS_G12V BRCA2 56 134 Tumor Type:overall -2.41 -5.48 -0.21 1357.54 1.00 918 55 133 1 TRUE 1.13
colorectal cancer KRAS_G12V NOTCH3 73 58 Metastasis -1.00 -2.19 -0.02 1222.65 1.00 759 71 56 2 TRUE 1.18
colorectal cancer KRAS_G12V NOTCH3 122 142 Primary -0.94 -1.83 -0.21 1057.19 1.00 1115 116 136 6 TRUE 1.66
non-small cell lung cancer KRAS_G12V NOTCH3 50 51 Metastasis 0.56 -0.51 1.57 1343.47 1.00 1288 45 46 5 TRUE 0.52
non-small cell lung cancer KRAS_G12V NOTCH3 119 77 Primary -0.26 -1.63 0.76 1074.99 1.00 2111 117 75 2 TRUE 0.17
uterine cancer KRAS_G12V NOTCH3 18 29 Metastasis -1.20 -3.09 0.33 537.31 1.00 336 17 28 1 TRUE 0.77
uterine cancer KRAS_G12V NOTCH3 38 62 Primary -1.31 -3.25 0.12 797.20 1.00 591 37 61 1 TRUE 0.95
colorectal cancer KRAS_G12V NOTCH3 195 200 Tumor Type:overall -0.96 -2.15 0.21 1283.53 1.00 1874 187 192 8 TRUE 0.95
non-small cell lung cancer KRAS_G12V NOTCH3 169 128 Tumor Type:overall 0.15 -1.30 1.56 1328.88 1.00 3399 162 121 7 TRUE 0.08
uterine cancer KRAS_G12V NOTCH3 56 91 Tumor Type:overall -1.25 -3.20 0.29 595.89 1.00 927 54 89 2 TRUE 0.81
colorectal cancer KRAS_G12V NOTCH4 73 33 Metastasis -1.21 -2.99 0.29 1353.66 1.00 775 71 31 2 TRUE 0.88
colorectal cancer KRAS_G12V NOTCH4 121 89 Primary -1.79 -3.64 -0.53 1434.48 1.00 1146 120 88 1 TRUE 1.61
non-small cell lung cancer KRAS_G12V NOTCH4 50 55 Metastasis 0.34 -0.59 1.13 1109.43 1.00 1282 47 52 3 TRUE 0.35
non-small cell lung cancer KRAS_G12V NOTCH4 119 84 Primary 0.32 -0.54 1.04 1017.37 1.00 2105 113 78 6 TRUE 0.38
uterine cancer KRAS_G12V NOTCH4 19 23 Metastasis -0.58 -2.58 1.14 900.99 1.01 342 17 21 2 TRUE 0.27
uterine cancer KRAS_G12V NOTCH4 38 42 Primary -1.30 -4.29 0.34 1167.85 1.00 603 38 42 0 TRUE 0.49
colorectal cancer KRAS_G12V NOTCH4 194 122 Tumor Type:overall -1.50 -3.40 0.18 1528.19 1.00 1921 191 119 3 TRUE 0.98
non-small cell lung cancer KRAS_G12V NOTCH4 169 139 Tumor Type:overall 0.33 -0.65 1.32 1413.75 1.00 3387 160 130 9 TRUE 0.28
uterine cancer KRAS_G12V NOTCH4 57 65 Tumor Type:overall -0.95 -3.24 0.78 855.77 1.00 945 55 63 2 TRUE 0.45
colorectal cancer KRAS_G12V FGFR3 81 14 Metastasis -1.16 -3.22 0.60 767.49 1.00 860 80 13 1 TRUE 0.62
colorectal cancer KRAS_G12V FGFR3 135 46 Primary -1.45 -3.23 -0.08 639.74 1.00 1321 134 45 1 TRUE 1.05
colorectal cancer KRAS_G12V FGFR3 216 60 Tumor Type:overall -1.31 -3.31 0.47 661.09 1.00 2181 214 58 2 TRUE 0.76
non-small cell lung cancer KRAS_G12V MAP3K13 51 23 Metastasis 1.02 -0.09 2.02 1320.99 1.00 1312 48 20 3 FALSE 1.24
non-small cell lung cancer KRAS_G12V MAP3K13 119 29 Primary 0.84 -0.26 1.77 1256.83 1.00 2153 116 26 3 FALSE 0.99
non-small cell lung cancer KRAS_G12V MAP3K13 170 52 Tumor Type:overall 0.91 -0.38 1.99 1406.10 1.00 3465 164 46 6 FALSE 0.85
colorectal cancer KRAS_G12V IGF1R 73 22 Metastasis -1.09 -2.92 0.25 1353.28 1.01 788 72 21 1 TRUE 0.77
colorectal cancer KRAS_G12V IGF1R 121 58 Primary -1.14 -2.52 0.10 1026.81 1.00 1170 119 56 2 TRUE 1.06
non-small cell lung cancer KRAS_G12V IGF1R 50 26 Metastasis -4.88 -12.25 -0.56 1169.29 1.00 1307 50 26 0 TRUE 1.01
non-small cell lung cancer KRAS_G12V IGF1R 119 28 Primary -4.86 -12.17 -0.56 1222.91 1.00 2151 119 28 0 TRUE 0.99
colorectal cancer KRAS_G12V IGF1R 194 80 Tumor Type:overall -1.11 -2.89 0.44 1197.14 1.00 1958 191 77 3 TRUE 0.76
non-small cell lung cancer KRAS_G12V IGF1R 169 54 Tumor Type:overall -4.79 -11.57 -0.65 1222.74 1.00 3458 169 54 0 TRUE 1.03
non-small cell lung cancer KRAS_G12V KEAP1 50 234 Metastasis 0.23 -0.38 0.84 1444.95 1.00 1119 38 222 12 FALSE 0.34
non-small cell lung cancer KRAS_G12V KEAP1 119 304 Primary -0.12 -0.68 0.37 1385.66 1.00 1902 106 291 13 FALSE 0.18
non-small cell lung cancer KRAS_G12V KEAP1 169 538 Tumor Type:overall 0.04 -0.98 0.99 1399.62 1.00 3021 144 513 25 FALSE 0.03
colorectal cancer KRAS_G12V KDM5C 73 14 Metastasis -2.05 -5.48 -0.03 1127.65 1.00 792 73 14 0 FALSE 0.78
colorectal cancer KRAS_G12V KDM5C 121 55 Primary -1.49 -3.43 -0.11 293.89 1.01 1178 119 53 2 FALSE 1.09
non-small cell lung cancer KRAS_G12V KDM5C 50 41 Metastasis 0.65 -0.41 1.67 1151.00 1.00 1296 46 37 4 FALSE 0.70
non-small cell lung cancer KRAS_G12V KDM5C 119 65 Primary 0.36 -0.56 1.12 1178.16 1.00 2122 115 61 4 FALSE 0.41
uterine cancer KRAS_G12V KDM5C 18 21 Metastasis -0.35 -1.93 1.00 686.15 1.00 342 17 20 1 FALSE 0.20
uterine cancer KRAS_G12V KDM5C 39 46 Primary -0.40 -1.85 0.83 793.40 1.00 607 37 44 2 FALSE 0.25
colorectal cancer KRAS_G12V KDM5C 194 69 Tumor Type:overall -1.71 -4.07 0.31 677.56 1.00 1970 192 67 2 FALSE 0.84
non-small cell lung cancer KRAS_G12V KDM5C 169 106 Tumor Type:overall 0.51 -0.64 1.61 1240.58 1.00 3418 161 98 8 FALSE 0.44
uterine cancer KRAS_G12V KDM5C 57 67 Tumor Type:overall -0.38 -2.00 1.01 769.68 1.00 949 54 64 3 FALSE 0.21
non-small cell lung cancer KRAS_G12V CDKN2A 52 92 Metastasis 0.00 -0.81 0.77 1377.26 1.00 1298 48 88 4 TRUE 0.00
non-small cell lung cancer KRAS_G12V CDKN2A 125 184 Primary -0.04 -0.72 0.55 1380.38 1.00 2084 116 175 9 TRUE 0.05
pancreatic cancer KRAS_G12V CDKN2A 129 121 Metastasis 0.24 -0.18 0.61 1521.63 1.00 388 100 92 29 TRUE 0.64
pancreatic cancer KRAS_G12V CDKN2A 261 173 Primary 0.39 0.06 0.72 1456.99 1.00 563 200 112 61 TRUE 1.75
non-small cell lung cancer KRAS_G12V CDKN2A 177 276 Tumor Type:overall -0.01 -0.96 0.88 1439.15 1.00 3382 164 263 13 TRUE 0.01
pancreatic cancer KRAS_G12V CDKN2A 390 294 Tumor Type:overall 0.31 -0.41 0.93 1454.80 1.00 951 300 204 90 TRUE 0.44
colorectal cancer KRAS_G12V EPHB1 73 25 Metastasis -1.12 -2.76 0.13 1003.93 1.00 781 72 24 1 FALSE 0.85
colorectal cancer KRAS_G12V EPHB1 121 57 Primary -1.14 -2.65 -0.05 900.16 1.00 1168 119 55 2 FALSE 1.02
non-small cell lung cancer KRAS_G12V EPHB1 50 59 Metastasis -0.61 -2.00 0.45 1418.28 1.00 1277 49 58 1 FALSE 0.50
non-small cell lung cancer KRAS_G12V EPHB1 119 99 Primary -0.50 -1.54 0.39 1349.79 1.00 2095 115 95 4 FALSE 0.50
colorectal cancer KRAS_G12V EPHB1 194 82 Tumor Type:overall -1.12 -2.80 0.21 1021.15 1.00 1949 191 79 3 FALSE 0.80
non-small cell lung cancer KRAS_G12V EPHB1 169 158 Tumor Type:overall -0.54 -1.77 0.57 1434.57 1.00 3372 164 153 5 FALSE 0.44
colorectal cancer KRAS_G12V IRS2 73 11 Metastasis -1.98 -6.02 0.33 1302.93 1.00 795 73 11 0 FALSE 0.64
colorectal cancer KRAS_G12V IRS2 122 76 Primary -1.16 -2.54 -0.04 1569.19 1.00 1154 119 73 3 FALSE 1.13
non-small cell lung cancer KRAS_G12V IRS2 50 36 Metastasis 0.39 -0.72 1.42 671.27 1.00 1301 47 33 3 FALSE 0.31
non-small cell lung cancer KRAS_G12V IRS2 119 48 Primary 0.04 -1.24 1.00 1250.11 1.00 2134 117 46 2 FALSE 0.03
uterine cancer KRAS_G12V IRS2 18 22 Metastasis -0.52 -3.42 0.84 1184.70 1.00 341 18 22 0 FALSE 0.21
uterine cancer KRAS_G12V IRS2 39 52 Primary -0.05 -1.32 1.00 734.54 1.01 597 35 48 4 FALSE 0.03
colorectal cancer KRAS_G12V IRS2 195 87 Tumor Type:overall -1.45 -4.18 0.98 1362.75 1.00 1949 192 84 3 FALSE 0.57
non-small cell lung cancer KRAS_G12V IRS2 169 84 Tumor Type:overall 0.24 -1.12 1.49 1208.82 1.00 3435 164 79 5 FALSE 0.14
uterine cancer KRAS_G12V IRS2 57 74 Tumor Type:overall -0.27 -2.30 1.03 1275.63 1.00 938 53 70 4 FALSE 0.13
colorectal cancer KRAS_G12V FANCA 73 12 Metastasis 0.04 -1.59 1.61 1389.16 1.00 797 71 10 2 TRUE 0.02
colorectal cancer KRAS_G12V FANCA 121 53 Primary -0.77 -2.22 0.33 1306.16 1.00 1173 119 51 2 TRUE 0.61
non-small cell lung cancer KRAS_G12V FANCA 50 34 Metastasis 0.39 -0.97 1.63 1258.88 1.00 1302 47 31 3 TRUE 0.26
non-small cell lung cancer KRAS_G12V FANCA 119 35 Primary -0.21 -1.88 0.97 1345.33 1.00 2147 118 34 1 TRUE 0.11
colorectal cancer KRAS_G12V FANCA 194 65 Tumor Type:overall -0.38 -2.29 1.47 1395.23 1.00 1970 190 61 4 TRUE 0.17
non-small cell lung cancer KRAS_G12V FANCA 169 69 Tumor Type:overall 0.08 -1.57 1.55 1349.33 1.00 3449 165 65 4 TRUE 0.04
non-small cell lung cancer KRAS_G12V IL7R 50 35 Metastasis -0.31 -1.77 1.02 1393.70 1.00 1299 48 33 2 FALSE 0.18
non-small cell lung cancer KRAS_G12V IL7R 119 56 Primary -0.62 -2.14 0.51 1047.57 1.00 2133 118 55 1 FALSE 0.42
non-small cell lung cancer KRAS_G12V IL7R 169 91 Tumor Type:overall -0.45 -1.95 0.96 1161.35 1.00 3432 166 88 3 FALSE 0.26
uterine cancer KRAS_G12V PPP2R1A 18 52 Metastasis 0.08 -0.88 1.01 684.00 1.00 319 14 48 4 FALSE 0.06
uterine cancer KRAS_G12V PPP2R1A 38 107 Primary -0.18 -1.13 0.61 300.51 1.01 538 34 103 4 FALSE 0.15
uterine cancer KRAS_G12V PPP2R1A 56 159 Tumor Type:overall -0.06 -1.20 0.93 676.56 1.00 857 48 151 8 FALSE 0.04
colorectal cancer KRAS_G12V PIK3CB 73 12 Metastasis -2.62 -6.17 -0.06 1347.61 1.00 796 73 12 0 FALSE 1.03
colorectal cancer KRAS_G12V PIK3CB 121 56 Primary -2.32 -4.97 -0.50 1083.65 1.00 1177 120 55 1 FALSE 1.32
colorectal cancer KRAS_G12V PIK3CB 194 68 Tumor Type:overall -2.39 -5.53 0.12 1167.96 1.00 1973 193 67 1 FALSE 1.01
colorectal cancer KRAS_G12V ERBB3 73 39 Metastasis -0.73 -1.88 0.25 1394.29 1.00 771 71 37 2 TRUE 0.75
colorectal cancer KRAS_G12V ERBB3 121 83 Primary -0.75 -1.74 0.08 1345.45 1.00 1152 117 79 4 TRUE 0.97
uterine cancer KRAS_G12V ERBB3 18 20 Metastasis -0.55 -2.38 0.92 1227.94 1.00 340 17 19 1 TRUE 0.30
uterine cancer KRAS_G12V ERBB3 38 60 Primary -0.63 -2.06 0.61 1350.55 1.00 586 36 58 2 TRUE 0.44
colorectal cancer KRAS_G12V ERBB3 194 122 Tumor Type:overall -0.74 -1.87 0.30 1347.74 1.00 1923 188 116 6 TRUE 0.73
uterine cancer KRAS_G12V ERBB3 56 80 Tumor Type:overall -0.56 -2.37 0.96 1357.79 1.00 926 53 77 3 TRUE 0.28
colorectal cancer KRAS_G12V SMAD4 81 149 Metastasis 0.41 -0.02 0.84 988.65 1.00 750 63 131 18 TRUE 1.23
colorectal cancer KRAS_G12V SMAD4 139 211 Primary 0.38 -0.03 0.75 1239.49 1.00 1196 114 186 25 TRUE 1.28
non-small cell lung cancer KRAS_G12V SMAD4 52 49 Metastasis -0.35 -1.89 0.75 1343.54 1.00 1333 51 48 1 TRUE 0.23
non-small cell lung cancer KRAS_G12V SMAD4 124 67 Primary -0.14 -1.30 0.78 1346.58 1.00 2188 120 63 4 TRUE 0.11
pancreatic cancer KRAS_G12V SMAD4 129 108 Metastasis 0.28 -0.15 0.76 1441.05 1.00 397 99 78 30 TRUE 0.65
pancreatic cancer KRAS_G12V SMAD4 257 167 Primary 0.00 -0.38 0.33 1540.35 1.00 550 213 123 44 TRUE 0.00
colorectal cancer KRAS_G12V SMAD4 220 360 Tumor Type:overall 0.39 -0.12 0.94 1114.72 1.00 1946 177 317 43 TRUE 0.79
non-small cell lung cancer KRAS_G12V SMAD4 176 116 Tumor Type:overall -0.25 -1.80 0.88 1324.62 1.00 3521 171 111 5 TRUE 0.15
pancreatic cancer KRAS_G12V SMAD4 386 275 Tumor Type:overall 0.12 -0.64 0.90 1616.78 1.00 947 312 201 74 TRUE 0.11
colorectal cancer KRAS_G12V ATM 81 71 Metastasis -0.40 -1.41 0.30 1281.62 1.00 818 78 68 3 TRUE 0.44
colorectal cancer KRAS_G12V ATM 138 160 Primary -0.01 -0.57 0.50 1504.09 1.00 1256 122 144 16 TRUE 0.01
non-small cell lung cancer KRAS_G12V ATM 53 122 Metastasis 0.67 0.04 1.29 1048.48 1.01 1279 44 113 9 TRUE 1.52
non-small cell lung cancer KRAS_G12V ATM 125 166 Primary 0.53 -0.03 1.01 1019.65 1.00 2114 112 153 13 TRUE 1.39
uterine cancer KRAS_G12V ATM 19 39 Metastasis -0.29 -1.55 0.84 1289.61 1.00 355 17 37 2 TRUE 0.20
uterine cancer KRAS_G12V ATM 46 127 Primary -0.40 -1.31 0.42 1503.23 1.00 655 41 122 5 TRUE 0.44
colorectal cancer KRAS_G12V ATM 219 231 Tumor Type:overall -0.21 -1.36 0.60 1489.30 1.00 2074 200 212 19 TRUE 0.17
non-small cell lung cancer KRAS_G12V ATM 178 288 Tumor Type:overall 0.59 -0.18 1.37 1547.50 1.00 3393 156 266 22 TRUE 0.86
uterine cancer KRAS_G12V ATM 65 166 Tumor Type:overall -0.33 -1.74 0.88 1387.87 1.00 1010 58 159 7 TRUE 0.20
colorectal cancer KRAS_G12V RB1 135 58 Primary -0.76 -2.10 0.33 1292.26 1.00 1321 132 55 3 TRUE 0.65
non-small cell lung cancer KRAS_G12V RB1 52 96 Metastasis -1.08 -2.52 0.04 1454.24 1.00 1289 50 94 2 TRUE 1.05
non-small cell lung cancer KRAS_G12V RB1 124 127 Primary -1.23 -2.53 -0.21 1561.35 1.00 2126 122 125 2 TRUE 1.44
uterine cancer KRAS_G12V RB1 19 29 Metastasis -1.52 -3.83 0.15 563.30 1.01 357 19 29 0 TRUE 0.84
uterine cancer KRAS_G12V RB1 46 65 Primary -1.29 -3.21 0.16 374.85 1.00 678 44 63 2 TRUE 0.91
colorectal cancer KRAS_G12V RB1 135 58 Tumor Type:overall -0.62 -4.58 4.03 1455.96 1.00 1321 132 55 3 TRUE 0.12
non-small cell lung cancer KRAS_G12V RB1 176 223 Tumor Type:overall -1.17 -2.53 -0.01 1570.38 1.00 3415 172 219 4 TRUE 1.11
uterine cancer KRAS_G12V RB1 65 94 Tumor Type:overall -1.38 -3.44 0.23 439.35 1.01 1035 63 92 2 TRUE 0.84
cancer of unknown primary KRAS_G12V KMT2D 45 113 Metastasis -0.61 -1.66 0.28 1111.47 1.00 568 40 108 5 FALSE 0.69
colorectal cancer KRAS_G12V KMT2D 73 82 Metastasis -1.14 -2.23 -0.20 1366.74 1.00 751 70 79 3 FALSE 1.54
colorectal cancer KRAS_G12V KMT2D 121 306 Primary -1.38 -2.17 -0.73 1477.31 1.00 1049 113 298 8 FALSE 4.04
non-small cell lung cancer KRAS_G12V KMT2D 50 125 Metastasis -0.21 -1.01 0.48 1487.80 1.00 1231 46 121 4 FALSE 0.23
non-small cell lung cancer KRAS_G12V KMT2D 119 203 Primary -0.19 -0.86 0.40 1205.74 1.00 2012 110 194 9 FALSE 0.25
pancreatic cancer KRAS_G12V KMT2D 126 34 Metastasis -0.33 -1.12 0.42 1312.32 1.00 428 120 28 6 FALSE 0.40
pancreatic cancer KRAS_G12V KMT2D 250 32 Primary -0.40 -1.15 0.29 1302.89 1.00 624 243 25 7 FALSE 0.55
uterine cancer KRAS_G12V KMT2D 18 91 Metastasis -0.61 -1.57 0.21 868.92 1.00 298 16 89 2 FALSE 0.78
uterine cancer KRAS_G12V KMT2D 38 173 Primary -0.52 -1.26 0.20 567.39 1.02 533 31 166 7 FALSE 0.80
cancer of unknown primary KRAS_G12V KMT2D 48 125 Tumor Type:overall -0.68 -2.32 0.70 1432.55 1.00 625 43 120 5 FALSE 0.45
colorectal cancer KRAS_G12V KMT2D 194 388 Tumor Type:overall -1.24 -2.74 0.21 1472.74 1.00 1800 183 377 11 FALSE 0.97
non-small cell lung cancer KRAS_G12V KMT2D 169 328 Tumor Type:overall -0.18 -0.98 0.58 1379.04 1.00 3243 156 315 13 FALSE 0.18
pancreatic cancer KRAS_G12V KMT2D 376 66 Tumor Type:overall -0.34 -1.37 0.78 1436.44 1.00 1052 363 53 13 FALSE 0.29
uterine cancer KRAS_G12V KMT2D 56 264 Tumor Type:overall -0.56 -1.41 0.24 803.64 1.01 831 47 255 9 FALSE 0.68
colorectal cancer KRAS_G12V TSC2 73 25 Metastasis -2.10 -5.78 -0.24 1310.62 1.00 784 73 25 0 TRUE 0.84
colorectal cancer KRAS_G12V TSC2 121 90 Primary -1.39 -2.84 -0.28 1564.10 1.00 1149 118 87 3 TRUE 1.49
non-small cell lung cancer KRAS_G12V TSC2 50 28 Metastasis 0.57 -0.63 1.78 1094.94 1.01 1308 47 25 3 TRUE 0.45
non-small cell lung cancer KRAS_G12V TSC2 119 44 Primary 0.17 -1.02 1.19 1181.25 1.00 2140 117 42 2 TRUE 0.12
uterine cancer KRAS_G12V TSC2 18 28 Metastasis -0.65 -2.59 1.00 919.05 1.00 339 16 26 2 TRUE 0.33
uterine cancer KRAS_G12V TSC2 38 46 Primary -1.39 -4.38 0.24 1100.23 1.00 602 38 46 0 TRUE 0.56
colorectal cancer KRAS_G12V TSC2 194 115 Tumor Type:overall -1.69 -4.31 0.23 1376.02 1.00 1933 191 112 3 TRUE 0.88
non-small cell lung cancer KRAS_G12V TSC2 169 72 Tumor Type:overall 0.36 -1.00 1.59 1211.77 1.00 3448 164 67 5 TRUE 0.22
uterine cancer KRAS_G12V TSC2 56 74 Tumor Type:overall -1.00 -3.41 0.91 1189.70 1.00 941 54 72 2 TRUE 0.46
colorectal cancer KRAS_G12V APC 107 1010 Metastasis 0.12 -0.27 0.49 1506.63 1.00 263 23 926 84 TRUE 0.26
colorectal cancer KRAS_G12V APC 194 1528 Primary 0.22 -0.09 0.54 1589.81 1.00 498 42 1376 152 TRUE 0.77
non-small cell lung cancer KRAS_G12V APC 52 65 Metastasis -1.29 -4.71 0.13 1272.18 1.00 1317 52 65 0 TRUE 0.55
non-small cell lung cancer KRAS_G12V APC 124 92 Primary -0.60 -1.74 0.37 1495.10 1.00 2167 120 88 4 TRUE 0.57
uterine cancer KRAS_G12V APC 19 47 Metastasis -1.51 -3.39 -0.13 912.39 1.00 357 18 46 1 TRUE 1.31
uterine cancer KRAS_G12V APC 45 80 Primary -1.57 -3.35 -0.31 932.76 1.00 681 44 79 1 TRUE 1.45
colorectal cancer KRAS_G12V APC 301 2538 Tumor Type:overall 0.16 -0.38 0.77 1385.50 1.00 761 65 2302 236 TRUE 0.21
non-small cell lung cancer KRAS_G12V APC 176 157 Tumor Type:overall -0.94 -3.03 0.48 1369.40 1.00 3484 172 153 4 TRUE 0.51
uterine cancer KRAS_G12V APC 64 127 Tumor Type:overall -1.54 -3.34 -0.20 838.06 1.00 1038 62 125 2 TRUE 1.40
colorectal cancer KRAS_G12V ERBB2 81 32 Metastasis -1.09 -2.48 -0.03 978.59 1.00 846 80 31 1 TRUE 1.09
colorectal cancer KRAS_G12V ERBB2 135 72 Primary -1.02 -2.28 -0.07 1083.52 1.00 1297 132 69 3 TRUE 1.15
non-small cell lung cancer KRAS_G12V ERBB2 52 46 Metastasis -2.40 -5.85 -0.34 606.87 1.01 1335 52 46 0 TRUE 1.01
non-small cell lung cancer KRAS_G12V ERBB2 124 83 Primary -2.23 -5.14 -0.46 487.90 1.00 2170 123 82 1 TRUE 1.22
uterine cancer KRAS_G12V ERBB2 19 18 Metastasis -5.00 -11.74 -0.91 296.62 1.01 363 19 18 0 TRUE 1.08
uterine cancer KRAS_G12V ERBB2 45 40 Primary -5.03 -11.73 -1.09 282.53 1.01 687 45 40 0 TRUE 1.07
colorectal cancer KRAS_G12V ERBB2 216 104 Tumor Type:overall -1.05 -2.53 0.08 1180.94 1.00 2143 212 100 4 TRUE 0.97
non-small cell lung cancer KRAS_G12V ERBB2 176 129 Tumor Type:overall -2.29 -5.41 -0.36 549.93 1.01 3505 175 128 1 TRUE 1.11
uterine cancer KRAS_G12V ERBB2 64 58 Tumor Type:overall -4.95 -11.69 -0.93 298.00 1.01 1050 64 58 0 TRUE 1.08
colorectal cancer KRAS_G12V JAK1 73 12 Metastasis -2.10 -5.50 0.20 1389.84 1.00 793 73 12 0 TRUE 0.74
colorectal cancer KRAS_G12V JAK1 121 63 Primary -1.50 -3.26 -0.19 1480.16 1.00 1173 119 61 2 TRUE 1.21
non-small cell lung cancer KRAS_G12V JAK1 50 20 Metastasis -0.78 -3.50 0.97 1382.88 1.00 1312 50 20 0 TRUE 0.29
non-small cell lung cancer KRAS_G12V JAK1 119 32 Primary -0.38 -2.25 1.04 1242.22 1.00 2152 117 30 2 TRUE 0.19
uterine cancer KRAS_G12V JAK1 18 39 Metastasis -0.37 -1.88 0.69 1209.92 1.00 331 17 38 1 TRUE 0.24
uterine cancer KRAS_G12V JAK1 39 106 Primary -0.12 -1.06 0.71 1413.34 1.00 567 33 100 6 TRUE 0.11
colorectal cancer KRAS_G12V JAK1 194 75 Tumor Type:overall -1.77 -4.51 0.54 1487.20 1.00 1966 192 73 2 TRUE 0.76
non-small cell lung cancer KRAS_G12V JAK1 169 52 Tumor Type:overall -0.55 -2.81 1.12 1270.70 1.00 3464 167 50 2 TRUE 0.23
uterine cancer KRAS_G12V JAK1 57 145 Tumor Type:overall -0.24 -1.66 0.96 1367.88 1.00 898 50 138 7 TRUE 0.15
uterine cancer KRAS_G12V CCND1 18 27 Metastasis 0.45 -0.62 1.40 935.49 1.00 335 16 25 2 TRUE 0.41
uterine cancer KRAS_G12V CCND1 38 42 Primary 0.50 -0.48 1.38 978.57 1.00 597 34 38 4 TRUE 0.53
uterine cancer KRAS_G12V CCND1 56 69 Tumor Type:overall 0.49 -0.61 1.50 1100.92 1.00 932 50 63 6 TRUE 0.44
colorectal cancer KRAS_G12V ARID2 73 31 Metastasis -0.83 -2.42 0.28 1435.56 1.00 780 72 30 1 FALSE 0.68
colorectal cancer KRAS_G12V ARID2 122 79 Primary -0.59 -1.52 0.17 1427.08 1.00 1154 117 74 5 FALSE 0.73
non-small cell lung cancer KRAS_G12V ARID2 50 74 Metastasis -0.99 -2.46 0.10 1398.50 1.00 1267 49 73 1 FALSE 0.90
non-small cell lung cancer KRAS_G12V ARID2 119 108 Primary -0.89 -2.08 0.06 1430.00 1.00 2081 116 105 3 FALSE 0.99
uterine cancer KRAS_G12V ARID2 18 27 Metastasis -1.70 -4.63 0.35 1286.34 1.00 342 17 26 1 FALSE 0.78
uterine cancer KRAS_G12V ARID2 38 44 Primary -2.00 -5.04 -0.09 1096.66 1.00 603 38 44 0 FALSE 0.91
colorectal cancer KRAS_G12V ARID2 195 110 Tumor Type:overall -0.70 -2.06 0.48 1394.78 1.00 1934 189 104 6 FALSE 0.54
non-small cell lung cancer KRAS_G12V ARID2 169 182 Tumor Type:overall -0.93 -2.34 0.19 1416.91 1.00 3348 165 178 4 FALSE 0.83
uterine cancer KRAS_G12V ARID2 56 71 Tumor Type:overall -1.84 -4.69 0.13 1215.04 1.00 945 55 70 1 FALSE 0.85
colorectal cancer KRAS_G12V SOX17 73 30 Metastasis -1.04 -2.57 0.11 959.65 1.00 779 72 29 1 FALSE 0.88
colorectal cancer KRAS_G12V SOX17 121 68 Primary -0.97 -2.28 0.08 570.02 1.00 1159 118 65 3 FALSE 0.97
non-small cell lung cancer KRAS_G12V SOX17 50 26 Metastasis 0.36 -0.95 1.52 1415.61 1.00 1308 48 24 2 FALSE 0.26
non-small cell lung cancer KRAS_G12V SOX17 119 35 Primary 0.21 -1.08 1.19 1212.06 1.00 2148 117 33 2 FALSE 0.15
uterine cancer KRAS_G12V SOX17 18 16 Metastasis -0.12 -2.93 1.21 1014.27 1.00 344 18 16 0 FALSE 0.04
uterine cancer KRAS_G12V SOX17 38 36 Primary 0.40 -0.82 1.42 1129.81 1.00 605 34 32 4 FALSE 0.31
colorectal cancer KRAS_G12V SOX17 194 98 Tumor Type:overall -1.00 -2.60 0.23 788.05 1.00 1938 190 94 4 FALSE 0.80
non-small cell lung cancer KRAS_G12V SOX17 169 61 Tumor Type:overall 0.29 -1.10 1.49 1537.34 1.00 3456 165 57 4 FALSE 0.18
uterine cancer KRAS_G12V SOX17 56 52 Tumor Type:overall 0.15 -1.74 1.48 1107.53 1.00 949 52 48 4 FALSE 0.07
colorectal cancer KRAS_G12V MTOR 73 41 Metastasis -0.10 -0.97 0.75 1487.67 1.00 772 69 37 4 TRUE 0.09
colorectal cancer KRAS_G12V MTOR 121 99 Primary -0.23 -1.01 0.44 1283.51 1.00 1145 114 92 7 TRUE 0.27
non-small cell lung cancer KRAS_G12V MTOR 50 39 Metastasis 0.00 -1.42 1.30 1427.47 1.00 1297 47 36 3 TRUE 0.00
non-small cell lung cancer KRAS_G12V MTOR 119 76 Primary -0.80 -2.51 0.33 1271.86 1.00 2106 118 75 1 TRUE 0.54
uterine cancer KRAS_G12V MTOR 19 19 Metastasis -0.06 -1.75 1.59 1399.24 1.00 343 17 17 2 TRUE 0.03
uterine cancer KRAS_G12V MTOR 38 71 Primary -1.08 -2.89 0.22 1282.29 1.00 583 37 70 1 TRUE 0.74
colorectal cancer KRAS_G12V MTOR 194 140 Tumor Type:overall -0.16 -1.21 0.81 1469.76 1.00 1917 183 129 11 TRUE 0.12
non-small cell lung cancer KRAS_G12V MTOR 169 115 Tumor Type:overall -0.41 -2.15 1.23 1451.74 1.00 3403 165 111 4 TRUE 0.20
uterine cancer KRAS_G12V MTOR 57 90 Tumor Type:overall -0.58 -2.65 1.49 1492.15 1.00 926 54 87 3 TRUE 0.24
non-small cell lung cancer KRAS_G12V RFWD2 50 22 Metastasis -4.80 -12.16 -0.48 790.50 1.00 1310 50 22 0 FALSE 0.99
non-small cell lung cancer KRAS_G12V RFWD2 119 35 Primary -4.85 -12.32 -0.66 823.22 1.00 2144 119 35 0 FALSE 1.00
non-small cell lung cancer KRAS_G12V RFWD2 169 57 Tumor Type:overall -4.75 -12.20 -0.46 811.59 1.00 3454 169 57 0 FALSE 0.99
colorectal cancer KRAS_G12V IRS1 73 19 Metastasis -0.30 -1.74 1.10 1596.03 1.00 789 71 17 2 FALSE 0.17
colorectal cancer KRAS_G12V IRS1 121 78 Primary -0.86 -2.13 0.14 1597.10 1.00 1155 118 75 3 FALSE 0.89
non-small cell lung cancer KRAS_G12V IRS1 50 30 Metastasis -0.32 -2.01 0.94 1370.96 1.00 1303 49 29 1 FALSE 0.17
non-small cell lung cancer KRAS_G12V IRS1 119 43 Primary -0.30 -1.70 0.89 1262.10 1.00 2141 117 41 2 FALSE 0.19
colorectal cancer KRAS_G12V IRS1 194 97 Tumor Type:overall -0.56 -2.30 1.17 1499.73 1.00 1944 189 92 5 FALSE 0.28
non-small cell lung cancer KRAS_G12V IRS1 169 73 Tumor Type:overall -0.31 -1.93 1.02 1310.95 1.00 3444 166 70 3 FALSE 0.16
colorectal cancer KRAS_G12V NOTCH1 81 39 Metastasis -2.05 -5.33 -0.33 1459.96 1.00 839 81 39 0 TRUE 0.90
colorectal cancer KRAS_G12V NOTCH1 136 133 Primary -0.99 -1.88 -0.20 1552.94 1.00 1270 130 127 6 TRUE 1.64
non-small cell lung cancer KRAS_G12V NOTCH1 52 52 Metastasis -0.93 -2.41 0.24 676.11 1.00 1332 51 51 1 TRUE 0.77
non-small cell lung cancer KRAS_G12V NOTCH1 124 78 Primary -0.94 -2.30 0.14 798.49 1.00 2178 122 76 2 TRUE 0.89
uterine cancer KRAS_G12V NOTCH1 19 34 Metastasis -2.25 -5.16 -0.26 831.95 1.00 352 19 34 0 TRUE 1.14
uterine cancer KRAS_G12V NOTCH1 45 56 Primary -2.12 -4.84 -0.25 704.82 1.00 686 44 55 1 TRUE 1.12
colorectal cancer KRAS_G12V NOTCH1 217 172 Tumor Type:overall -1.45 -3.61 0.18 1696.28 1.00 2109 211 166 6 TRUE 0.85
non-small cell lung cancer KRAS_G12V NOTCH1 176 130 Tumor Type:overall -0.93 -2.49 0.36 872.57 1.00 3510 173 127 3 TRUE 0.74
uterine cancer KRAS_G12V NOTCH1 64 90 Tumor Type:overall -2.17 -4.97 -0.17 719.17 1.00 1038 63 89 1 TRUE 1.07
colorectal cancer KRAS_G12V NTRK1 73 16 Metastasis -0.53 -2.14 0.77 1411.52 1.00 790 72 15 1 TRUE 0.32
colorectal cancer KRAS_G12V NTRK1 121 48 Primary -0.53 -1.82 0.48 1169.41 1.00 1178 118 45 3 TRUE 0.44
non-small cell lung cancer KRAS_G12V NTRK1 50 44 Metastasis -2.15 -5.61 0.05 1241.68 1.00 1289 50 44 0 TRUE 0.85
non-small cell lung cancer KRAS_G12V NTRK1 119 44 Primary -1.75 -4.35 0.11 1268.64 1.00 2137 118 43 1 TRUE 0.85
colorectal cancer KRAS_G12V NTRK1 194 64 Tumor Type:overall -0.53 -2.23 0.94 1356.10 1.00 1968 190 60 4 TRUE 0.30
non-small cell lung cancer KRAS_G12V NTRK1 169 88 Tumor Type:overall -1.94 -4.90 0.22 1353.51 1.00 3426 168 87 1 TRUE 0.82
non-small cell lung cancer KRAS_G12V INPP4A 50 21 Metastasis 0.03 -1.61 1.33 1372.16 1.00 1313 49 20 1 FALSE 0.01
non-small cell lung cancer KRAS_G12V INPP4A 119 32 Primary 0.04 -1.51 1.21 1460.99 1.00 2149 117 30 2 FALSE 0.02
uterine cancer KRAS_G12V INPP4A 18 20 Metastasis -1.73 -4.87 0.23 375.18 1.00 344 18 20 0 FALSE 0.73
uterine cancer KRAS_G12V INPP4A 38 42 Primary -1.58 -4.44 0.19 377.21 1.01 610 37 41 1 FALSE 0.72
non-small cell lung cancer KRAS_G12V INPP4A 169 53 Tumor Type:overall 0.02 -1.64 1.35 1469.21 1.00 3462 166 50 3 FALSE 0.01
uterine cancer KRAS_G12V INPP4A 56 62 Tumor Type:overall -1.64 -4.60 0.26 414.10 1.00 954 55 61 1 FALSE 0.73
colorectal cancer KRAS_G12V CASP8 73 17 Metastasis -5.66 -12.64 -1.18 1271.02 1.00 790 73 17 0 FALSE 1.26
colorectal cancer KRAS_G12V CASP8 121 79 Primary -5.86 -12.71 -1.87 1271.15 1.00 1153 121 79 0 FALSE 1.39
uterine cancer KRAS_G12V CASP8 18 19 Metastasis -1.66 -4.24 0.51 35.77 1.07 344 17 18 1 FALSE 0.63
uterine cancer KRAS_G12V CASP8 38 44 Primary -2.05 -5.15 0.05 60.02 1.05 601 38 44 0 FALSE 0.82
colorectal cancer KRAS_G12V CASP8 194 96 Tumor Type:overall -5.56 -12.29 -1.27 1244.11 1.00 1943 194 96 0 FALSE 1.32
uterine cancer KRAS_G12V CASP8 56 63 Tumor Type:overall -1.82 -4.45 0.35 43.78 1.06 945 55 62 1 FALSE 0.71
colorectal cancer KRAS_G12V SETD2 73 29 Metastasis -3.14 -6.61 -0.90 1292.91 1.00 781 73 29 0 FALSE 1.47
colorectal cancer KRAS_G12V SETD2 121 84 Primary -2.84 -5.33 -1.06 1465.75 1.00 1153 120 83 1 FALSE 1.94
non-small cell lung cancer KRAS_G12V SETD2 50 93 Metastasis -0.72 -2.13 0.26 1283.04 1.00 1257 49 92 1 FALSE 0.64
non-small cell lung cancer KRAS_G12V SETD2 120 132 Primary -0.40 -1.24 0.40 1167.18 1.00 2069 114 126 6 FALSE 0.46
uterine cancer KRAS_G12V SETD2 18 27 Metastasis -0.65 -2.31 0.61 672.35 1.00 339 17 26 1 FALSE 0.43
uterine cancer KRAS_G12V SETD2 38 62 Primary -0.67 -2.17 0.34 511.06 1.00 594 36 60 2 FALSE 0.52
colorectal cancer KRAS_G12V SETD2 194 113 Tumor Type:overall -2.91 -5.86 -0.90 1446.73 1.00 1934 193 112 1 FALSE 1.69
non-small cell lung cancer KRAS_G12V SETD2 170 225 Tumor Type:overall -0.56 -1.83 0.48 1402.27 1.00 3326 163 218 7 FALSE 0.45
uterine cancer KRAS_G12V SETD2 56 89 Tumor Type:overall -0.64 -2.28 0.66 680.00 1.00 933 53 86 3 FALSE 0.39
colorectal cancer KRAS_G12V PBRM1 73 15 Metastasis -2.37 -6.49 -0.10 1491.38 1.00 792 73 15 0 TRUE 0.85
colorectal cancer KRAS_G12V PBRM1 121 79 Primary -1.71 -3.45 -0.39 1589.02 1.00 1154 119 77 2 TRUE 1.53
non-small cell lung cancer KRAS_G12V PBRM1 50 54 Metastasis -0.36 -2.04 0.77 1464.97 1.00 1287 49 53 1 TRUE 0.23
non-small cell lung cancer KRAS_G12V PBRM1 121 60 Primary -0.06 -1.21 0.88 1173.42 1.00 2128 117 56 4 TRUE 0.04
colorectal cancer KRAS_G12V PBRM1 194 94 Tumor Type:overall -1.95 -4.74 0.35 1451.51 1.00 1946 192 92 2 TRUE 0.91
non-small cell lung cancer KRAS_G12V PBRM1 171 114 Tumor Type:overall -0.24 -1.69 1.02 1502.94 1.00 3415 166 109 5 TRUE 0.14
colorectal cancer KRAS_G12V EPHA3 73 34 Metastasis 0.18 -0.82 1.11 394.80 1.01 777 68 29 5 FALSE 0.15
colorectal cancer KRAS_G12V EPHA3 122 79 Primary -0.19 -1.07 0.57 609.08 1.00 1155 117 74 5 FALSE 0.18
non-small cell lung cancer KRAS_G12V EPHA3 50 83 Metastasis 0.24 -0.56 0.98 1427.22 1.00 1258 46 79 4 FALSE 0.27
non-small cell lung cancer KRAS_G12V EPHA3 119 159 Primary 0.23 -0.42 0.79 1330.47 1.00 2046 109 149 10 FALSE 0.34
uterine cancer KRAS_G12V EPHA3 18 22 Metastasis -4.68 -11.16 -1.01 36.76 1.09 344 18 22 0 FALSE 0.97
uterine cancer KRAS_G12V EPHA3 38 56 Primary -4.75 -11.19 -1.31 33.26 1.09 598 38 56 0 FALSE 1.00
colorectal cancer KRAS_G12V EPHA3 195 113 Tumor Type:overall 0.00 -1.03 1.04 701.26 1.00 1932 185 103 10 FALSE 0.00
non-small cell lung cancer KRAS_G12V EPHA3 169 242 Tumor Type:overall 0.24 -0.63 1.12 1301.31 1.00 3304 155 228 14 FALSE 0.23
uterine cancer KRAS_G12V EPHA3 56 78 Tumor Type:overall -4.62 -11.10 -1.07 38.99 1.08 942 56 78 0 FALSE 0.97
colorectal cancer KRAS_G12V KIT 81 17 Metastasis -2.24 -5.16 -0.21 233.12 1.01 856 81 17 0 TRUE 1.04
colorectal cancer KRAS_G12V KIT 135 37 Primary -2.11 -4.87 -0.29 196.49 1.01 1330 134 36 1 TRUE 1.09
non-small cell lung cancer KRAS_G12V KIT 52 30 Metastasis 0.13 -1.19 1.19 664.60 1.00 1350 51 29 1 TRUE 0.08
non-small cell lung cancer KRAS_G12V KIT 124 51 Primary 0.26 -0.79 1.13 695.27 1.00 2205 120 47 4 TRUE 0.23
colorectal cancer KRAS_G12V KIT 216 54 Tumor Type:overall -2.14 -4.86 -0.18 198.33 1.01 2186 215 53 1 TRUE 1.06
non-small cell lung cancer KRAS_G12V KIT 176 81 Tumor Type:overall 0.21 -1.16 1.39 1086.50 1.00 3555 171 76 5 TRUE 0.13
colorectal cancer KRAS_G12V KDR 81 15 Metastasis -0.87 -2.82 0.76 1568.72 1.00 859 80 14 1 TRUE 0.48
colorectal cancer KRAS_G12V KDR 135 60 Primary -1.10 -2.53 0.01 1574.52 1.00 1315 133 58 2 TRUE 0.99
non-small cell lung cancer KRAS_G12V KDR 52 51 Metastasis 0.13 -0.86 1.06 782.78 1.01 1333 49 48 3 TRUE 0.10
non-small cell lung cancer KRAS_G12V KDR 124 103 Primary -0.02 -0.90 0.69 1423.52 1.00 2157 119 98 5 TRUE 0.02
colorectal cancer KRAS_G12V KDR 216 75 Tumor Type:overall -0.95 -2.84 0.73 1683.90 1.00 2174 213 72 3 TRUE 0.53
non-small cell lung cancer KRAS_G12V KDR 176 154 Tumor Type:overall 0.05 -0.96 0.97 1286.14 1.01 3490 168 146 8 TRUE 0.04
colorectal cancer KRAS_G12V RICTOR 73 11 Metastasis -1.75 -5.59 0.40 1287.42 1.00 796 73 11 0 FALSE 0.54
colorectal cancer KRAS_G12V RICTOR 121 59 Primary -0.92 -2.41 0.21 1409.38 1.00 1173 118 56 3 FALSE 0.76
non-small cell lung cancer KRAS_G12V RICTOR 50 24 Metastasis -1.26 -3.97 0.64 109.39 1.03 1310 49 23 1 FALSE 0.50
non-small cell lung cancer KRAS_G12V RICTOR 119 40 Primary -1.69 -5.19 0.23 68.24 1.05 2141 119 40 0 FALSE 0.61
uterine cancer KRAS_G12V RICTOR 18 14 Metastasis -1.55 -4.75 0.40 222.44 1.02 346 18 14 0 FALSE 0.58
uterine cancer KRAS_G12V RICTOR 38 42 Primary -1.38 -4.11 0.30 191.82 1.02 607 37 41 1 FALSE 0.61
colorectal cancer KRAS_G12V RICTOR 194 70 Tumor Type:overall -1.30 -4.19 0.75 1311.25 1.00 1969 191 67 3 FALSE 0.53
non-small cell lung cancer KRAS_G12V RICTOR 169 64 Tumor Type:overall -1.44 -4.45 0.54 97.28 1.04 3451 168 63 1 FALSE 0.55
uterine cancer KRAS_G12V RICTOR 56 56 Tumor Type:overall -1.43 -4.31 0.46 232.85 1.02 953 55 55 1 FALSE 0.57
colorectal cancer KRAS_G12V RAD50 73 18 Metastasis -1.92 -4.85 0.03 750.13 1.01 791 72 17 1 FALSE 0.93
colorectal cancer KRAS_G12V RAD50 121 42 Primary -2.38 -5.45 -0.51 610.34 1.00 1182 121 42 0 FALSE 1.13
colorectal cancer KRAS_G12V RAD50 194 60 Tumor Type:overall -2.10 -5.01 -0.07 760.61 1.00 1973 193 59 1 FALSE 1.02
colorectal cancer KRAS_G12V CSF1R 81 18 Metastasis -1.18 -2.97 0.31 870.06 1.00 860 80 17 1 TRUE 0.78
colorectal cancer KRAS_G12V CSF1R 135 38 Primary -1.28 -3.06 0.14 806.85 1.00 1328 134 37 1 TRUE 0.90
non-small cell lung cancer KRAS_G12V CSF1R 52 31 Metastasis 0.59 -0.56 1.56 1427.40 1.00 1352 50 29 2 TRUE 0.54
non-small cell lung cancer KRAS_G12V CSF1R 124 38 Primary 0.63 -0.40 1.50 1421.25 1.00 2216 120 34 4 TRUE 0.70
colorectal cancer KRAS_G12V CSF1R 216 56 Tumor Type:overall -1.22 -3.08 0.25 841.85 1.00 2188 214 54 2 TRUE 0.79
non-small cell lung cancer KRAS_G12V CSF1R 176 69 Tumor Type:overall 0.61 -0.60 1.67 1401.18 1.00 3568 170 63 6 TRUE 0.52
non-small cell lung cancer KRAS_G12V PARK2 50 31 Metastasis -0.24 -2.00 1.09 1429.26 1.00 1302 49 30 1 FALSE 0.12
non-small cell lung cancer KRAS_G12V PARK2 119 34 Primary -0.16 -1.58 1.06 1445.72 1.00 2147 117 32 2 FALSE 0.09
non-small cell lung cancer KRAS_G12V PARK2 169 65 Tumor Type:overall -0.20 -1.89 1.19 1482.96 1.00 3449 166 62 3 FALSE 0.10
non-small cell lung cancer KRAS_G12V NTRK2 50 22 Metastasis -0.58 -3.29 0.95 1226.17 1.00 1312 50 22 0 FALSE 0.21
non-small cell lung cancer KRAS_G12V NTRK2 119 45 Primary -0.13 -1.62 0.99 1473.08 1.00 2140 116 42 3 FALSE 0.08
non-small cell lung cancer KRAS_G12V NTRK2 169 67 Tumor Type:overall -0.36 -2.57 1.08 1394.93 1.00 3452 166 64 3 FALSE 0.16
colorectal cancer KRAS_G12V PTCH1 73 38 Metastasis -1.86 -5.22 -0.34 1382.87 1.00 776 73 38 0 TRUE 0.85
colorectal cancer KRAS_G12V PTCH1 121 107 Primary -1.01 -2.02 -0.14 1479.75 1.00 1142 116 102 5 TRUE 1.45
non-small cell lung cancer KRAS_G12V PTCH1 50 27 Metastasis -0.14 -1.65 1.19 1341.59 1.00 1307 49 26 1 TRUE 0.07
non-small cell lung cancer KRAS_G12V PTCH1 119 35 Primary -0.09 -1.48 1.00 1236.95 1.00 2146 117 33 2 TRUE 0.05
uterine cancer KRAS_G12V PTCH1 18 14 Metastasis -5.36 -12.56 -0.66 1225.59 1.00 347 18 14 0 TRUE 1.13
uterine cancer KRAS_G12V PTCH1 38 55 Primary -5.47 -12.52 -1.22 1327.06 1.00 593 38 55 0 TRUE 1.24
colorectal cancer KRAS_G12V PTCH1 194 145 Tumor Type:overall -1.40 -3.75 0.14 1416.18 1.00 1918 189 140 5 TRUE 0.85
non-small cell lung cancer KRAS_G12V PTCH1 169 62 Tumor Type:overall -0.12 -1.64 1.28 1249.80 1.00 3453 166 59 3 TRUE 0.06
uterine cancer KRAS_G12V PTCH1 56 69 Tumor Type:overall -5.27 -12.06 -0.90 1305.72 1.00 940 56 69 0 TRUE 1.18
colorectal cancer KRAS_G12V TET1 73 35 Metastasis -2.78 -5.70 -0.90 801.34 1.01 779 73 35 0 FALSE 1.75
colorectal cancer KRAS_G12V TET1 121 68 Primary -2.68 -5.31 -0.89 762.66 1.00 1169 120 67 1 FALSE 1.84
non-small cell lung cancer KRAS_G12V TET1 50 58 Metastasis -0.08 -1.32 0.95 1514.19 1.00 1283 48 56 2 FALSE 0.05
non-small cell lung cancer KRAS_G12V TET1 119 68 Primary 0.01 -1.06 0.85 1127.50 1.00 2120 115 64 4 FALSE 0.01
uterine cancer KRAS_G12V TET1 18 19 Metastasis -5.43 -12.46 -1.07 1277.99 1.00 345 18 19 0 FALSE 1.20
uterine cancer KRAS_G12V TET1 38 57 Primary -5.42 -12.38 -1.13 1270.37 1.00 596 38 57 0 FALSE 1.22
colorectal cancer KRAS_G12V TET1 194 103 Tumor Type:overall -2.72 -5.48 -0.86 762.35 1.01 1948 193 102 1 FALSE 1.76
non-small cell lung cancer KRAS_G12V TET1 169 126 Tumor Type:overall -0.04 -1.44 1.14 1354.75 1.00 3403 163 120 6 FALSE 0.02
uterine cancer KRAS_G12V TET1 56 76 Tumor Type:overall -5.39 -11.97 -1.05 1233.89 1.00 941 56 76 0 FALSE 1.22
colorectal cancer KRAS_G12V FGFR2 81 19 Metastasis -1.27 -3.68 0.18 821.49 1.00 854 81 19 0 TRUE 0.70
colorectal cancer KRAS_G12V FGFR2 135 34 Primary -1.05 -2.80 0.26 1138.10 1.00 1334 133 32 2 TRUE 0.76
uterine cancer KRAS_G12V FGFR2 19 23 Metastasis -2.53 -5.62 -0.36 692.09 1.00 358 19 23 0 TRUE 1.18
uterine cancer KRAS_G12V FGFR2 45 80 Primary -2.35 -4.65 -0.43 280.63 1.01 652 44 79 1 TRUE 1.38
colorectal cancer KRAS_G12V FGFR2 216 53 Tumor Type:overall -1.16 -3.40 0.26 857.34 1.00 2188 214 51 2 TRUE 0.71
uterine cancer KRAS_G12V FGFR2 64 103 Tumor Type:overall -2.43 -5.16 -0.20 388.44 1.01 1010 63 102 1 TRUE 1.20
colorectal cancer KRAS_G12V TBX3 73 18 Metastasis -0.59 -2.09 0.63 1217.05 1.00 789 72 17 1 FALSE 0.40
colorectal cancer KRAS_G12V TBX3 121 62 Primary -0.48 -1.55 0.45 1374.56 1.00 1174 117 58 4 FALSE 0.45
non-small cell lung cancer KRAS_G12V TBX3 50 60 Metastasis 0.16 -0.91 1.22 1169.90 1.00 1282 46 56 4 FALSE 0.11
non-small cell lung cancer KRAS_G12V TBX3 119 77 Primary -0.38 -1.72 0.60 1261.26 1.00 2107 117 75 2 FALSE 0.30
uterine cancer KRAS_G12V TBX3 18 12 Metastasis -4.88 -11.52 -0.61 769.00 1.00 347 18 12 0 FALSE 1.03
uterine cancer KRAS_G12V TBX3 38 42 Primary -4.97 -11.37 -0.87 648.38 1.00 603 38 42 0 FALSE 1.08
colorectal cancer KRAS_G12V TBX3 194 80 Tumor Type:overall -0.53 -2.02 0.81 1457.23 1.00 1963 189 75 5 FALSE 0.32
non-small cell lung cancer KRAS_G12V TBX3 169 137 Tumor Type:overall -0.10 -1.59 1.23 1449.60 1.00 3389 163 131 6 FALSE 0.05
uterine cancer KRAS_G12V TBX3 56 54 Tumor Type:overall -4.83 -11.20 -0.63 646.39 1.00 950 56 54 0 FALSE 1.07
colorectal cancer KRAS_G12V HNF1A 135 43 Primary -5.98 -15.42 -1.07 789.36 1.00 1320 135 43 0 TRUE 0.87
colorectal cancer KRAS_G12V HNF1A 135 43 Tumor Type:overall -4.35 -11.21 2.62 698.57 1.00 1320 135 43 0 TRUE 0.68
colorectal cancer KRAS_G12V DICER1 73 27 Metastasis -2.51 -5.39 -0.58 956.73 1.00 783 73 27 0 TRUE 1.40
colorectal cancer KRAS_G12V DICER1 121 49 Primary -2.36 -4.88 -0.51 872.51 1.00 1181 120 48 1 TRUE 1.47
non-small cell lung cancer KRAS_G12V DICER1 50 33 Metastasis -0.50 -2.36 1.10 1175.01 1.00 1304 48 31 2 TRUE 0.25
non-small cell lung cancer KRAS_G12V DICER1 119 57 Primary -1.35 -4.87 0.08 52.66 1.03 2125 119 57 0 TRUE 0.50
uterine cancer KRAS_G12V DICER1 20 18 Metastasis 1.24 -0.33 2.64 769.58 1.00 350 16 14 4 TRUE 0.99
uterine cancer KRAS_G12V DICER1 38 63 Primary -0.88 -2.97 0.57 1516.86 1.00 592 37 62 1 TRUE 0.49
colorectal cancer KRAS_G12V DICER1 194 76 Tumor Type:overall -2.42 -5.09 -0.44 915.97 1.00 1964 193 75 1 TRUE 1.41
non-small cell lung cancer KRAS_G12V DICER1 169 90 Tumor Type:overall -0.90 -3.38 0.68 100.80 1.02 3429 167 88 2 TRUE 0.41
uterine cancer KRAS_G12V DICER1 58 81 Tumor Type:overall 0.15 -2.48 2.41 1238.67 1.00 942 53 76 5 TRUE 0.05
colorectal cancer KRAS_G12V SMAD3 74 38 Metastasis 0.50 -0.21 1.26 738.63 1.00 776 67 31 7 TRUE 0.72
colorectal cancer KRAS_G12V SMAD3 121 69 Primary 0.23 -0.52 0.82 953.79 1.00 1168 115 63 6 TRUE 0.28
colorectal cancer KRAS_G12V SMAD3 195 107 Tumor Type:overall 0.36 -0.52 1.23 962.87 1.00 1944 182 94 13 TRUE 0.35
colorectal cancer KRAS_G12V NTRK3 73 15 Metastasis -1.51 -4.92 0.38 1404.58 1.00 792 73 15 0 FALSE 0.57
colorectal cancer KRAS_G12V NTRK3 121 55 Primary -0.88 -2.25 0.24 1291.34 1.00 1174 118 52 3 FALSE 0.76
non-small cell lung cancer KRAS_G12V NTRK3 50 81 Metastasis -1.39 -4.25 -0.01 806.99 1.01 1257 50 81 0 FALSE 0.71
non-small cell lung cancer KRAS_G12V NTRK3 119 126 Primary -0.78 -1.63 0.26 17.79 1.11 2078 114 121 5 FALSE 0.94
colorectal cancer KRAS_G12V NTRK3 194 70 Tumor Type:overall -1.13 -3.40 0.70 1411.36 1.00 1966 191 67 3 FALSE 0.56
non-small cell lung cancer KRAS_G12V NTRK3 169 207 Tumor Type:overall -1.06 -2.95 0.30 1217.02 1.01 3335 164 202 5 FALSE 0.72
colorectal cancer KRAS_G12V AXIN1 73 17 Metastasis -2.04 -4.77 0.27 340.15 1.01 792 72 16 1 FALSE 0.89
colorectal cancer KRAS_G12V AXIN1 121 54 Primary -2.86 -6.29 -0.82 839.32 1.00 1172 121 54 0 FALSE 1.41
colorectal cancer KRAS_G12V AXIN1 194 71 Tumor Type:overall -2.40 -5.29 0.10 628.57 1.00 1964 193 70 1 FALSE 1.08
colorectal cancer KRAS_G12V GRIN2A 73 41 Metastasis -0.84 -1.93 0.13 1556.63 1.00 767 71 39 2 FALSE 0.94
colorectal cancer KRAS_G12V GRIN2A 121 95 Primary -0.86 -1.88 -0.04 1480.39 1.00 1142 117 91 4 FALSE 1.21
non-small cell lung cancer KRAS_G12V GRIN2A 50 80 Metastasis 0.38 -0.48 1.14 857.63 1.00 1261 45 75 5 FALSE 0.46
non-small cell lung cancer KRAS_G12V GRIN2A 119 113 Primary 0.25 -0.53 0.90 1059.47 1.00 2081 112 106 7 FALSE 0.31
uterine cancer KRAS_G12V GRIN2A 18 20 Metastasis -0.59 -2.44 0.94 61.23 1.04 345 17 19 1 FALSE 0.29
uterine cancer KRAS_G12V GRIN2A 38 57 Primary -0.65 -2.34 0.59 51.80 1.05 598 36 55 2 FALSE 0.40
colorectal cancer KRAS_G12V GRIN2A 194 136 Tumor Type:overall -0.85 -2.04 0.29 1573.64 1.00 1909 188 130 6 FALSE 0.80
non-small cell lung cancer KRAS_G12V GRIN2A 169 193 Tumor Type:overall 0.31 -0.72 1.17 1191.03 1.00 3342 157 181 12 FALSE 0.29
uterine cancer KRAS_G12V GRIN2A 56 77 Tumor Type:overall -0.63 -2.46 0.90 66.79 1.04 943 53 74 3 FALSE 0.32
colorectal cancer KRAS_G12V PALB2 121 47 Primary -6.08 -15.99 -1.19 1005.82 1.00 1177 121 47 0 TRUE 0.71
non-small cell lung cancer KRAS_G12V PALB2 50 28 Metastasis 0.13 -1.51 1.37 1482.97 1.00 1308 49 27 1 TRUE 0.07
non-small cell lung cancer KRAS_G12V PALB2 119 32 Primary 0.32 -0.92 1.39 1517.83 1.00 2150 116 29 3 TRUE 0.23
colorectal cancer KRAS_G12V PALB2 121 47 Tumor Type:overall -4.32 -11.80 2.44 1376.32 1.00 1177 121 47 0 TRUE 0.67
non-small cell lung cancer KRAS_G12V PALB2 169 60 Tumor Type:overall 0.23 -1.50 1.55 1560.54 1.00 3458 165 56 4 TRUE 0.12
colorectal cancer KRAS_G12V CTCF 73 24 Metastasis -0.92 -2.60 0.31 1495.73 1.00 786 72 23 1 FALSE 0.71
colorectal cancer KRAS_G12V CTCF 121 66 Primary -0.87 -2.22 0.15 1400.07 1.00 1166 118 63 3 FALSE 0.87
uterine cancer KRAS_G12V CTCF 18 45 Metastasis -0.18 -1.28 0.81 1433.85 1.00 317 16 43 2 FALSE 0.14
uterine cancer KRAS_G12V CTCF 38 123 Primary -0.19 -1.08 0.60 1225.32 1.00 537 32 117 6 FALSE 0.19
colorectal cancer KRAS_G12V CTCF 194 90 Tumor Type:overall -0.91 -2.45 0.33 1382.03 1.00 1952 190 86 4 FALSE 0.67
uterine cancer KRAS_G12V CTCF 56 168 Tumor Type:overall -0.19 -1.42 0.95 1461.85 1.00 854 48 160 8 FALSE 0.13
colorectal cancer KRAS_G12V CDH1 81 13 Metastasis -0.24 -1.59 1.01 158.95 1.04 863 80 12 1 TRUE 0.14
colorectal cancer KRAS_G12V CDH1 136 41 Primary -0.13 -1.07 0.85 38.16 1.09 1330 132 37 4 TRUE 0.10
colorectal cancer KRAS_G12V CDH1 217 54 Tumor Type:overall -0.15 -1.39 1.17 136.21 1.04 2193 212 49 5 TRUE 0.08
colorectal cancer KRAS_G12V CDK12 73 21 Metastasis -1.85 -5.22 -0.02 1342.94 1.00 789 73 21 0 FALSE 0.75
colorectal cancer KRAS_G12V CDK12 121 69 Primary -1.14 -2.67 -0.05 1391.79 1.00 1163 118 66 3 FALSE 1.07
non-small cell lung cancer KRAS_G12V CDK12 50 24 Metastasis -4.87 -11.23 -0.76 426.57 1.01 1308 50 24 0 FALSE 1.10
non-small cell lung cancer KRAS_G12V CDK12 119 35 Primary -4.88 -11.23 -0.76 445.01 1.01 2146 119 35 0 FALSE 1.11
colorectal cancer KRAS_G12V CDK12 194 90 Tumor Type:overall -1.48 -4.00 0.27 1314.38 1.00 1952 191 87 3 FALSE 0.81
non-small cell lung cancer KRAS_G12V CDK12 169 59 Tumor Type:overall -4.83 -10.86 -0.78 410.32 1.01 3454 169 59 0 FALSE 1.11
non-small cell lung cancer KRAS_G12V STK11 52 205 Metastasis 0.66 0.14 1.21 1398.53 1.00 1191 38 191 14 TRUE 1.87
non-small cell lung cancer KRAS_G12V STK11 126 338 Primary 0.55 0.14 0.96 996.62 1.00 1951 100 312 26 TRUE 2.11
non-small cell lung cancer KRAS_G12V STK11 178 543 Tumor Type:overall 0.59 -0.12 1.29 1167.89 1.00 3142 138 503 40 TRUE 0.92
colorectal cancer KRAS_G12V DNMT1 73 27 Metastasis -1.63 -3.56 -0.15 961.76 1.00 783 72 26 1 FALSE 1.25
colorectal cancer KRAS_G12V DNMT1 121 63 Primary -1.75 -3.47 -0.41 929.38 1.00 1164 120 62 1 FALSE 1.57
colorectal cancer KRAS_G12V DNMT1 194 90 Tumor Type:overall -1.69 -3.70 -0.14 1110.59 1.00 1947 192 88 2 FALSE 1.29
colorectal cancer KRAS_G12V BRD4 73 22 Metastasis -0.90 -2.57 0.36 1384.87 1.00 787 72 21 1 FALSE 0.62
colorectal cancer KRAS_G12V BRD4 121 66 Primary -0.84 -2.10 0.12 1401.02 1.00 1161 118 63 3 FALSE 0.85
non-small cell lung cancer KRAS_G12V BRD4 50 27 Metastasis -1.67 -5.41 0.57 929.76 1.00 1307 50 27 0 FALSE 0.52
non-small cell lung cancer KRAS_G12V BRD4 119 26 Primary -1.28 -4.24 0.64 836.59 1.00 2154 118 25 1 FALSE 0.53
uterine cancer KRAS_G12V BRD4 18 18 Metastasis -5.14 -11.51 -0.92 821.44 1.00 341 18 18 0 FALSE 1.19
uterine cancer KRAS_G12V BRD4 38 52 Primary -5.20 -11.55 -1.07 771.20 1.00 596 38 52 0 FALSE 1.23
colorectal cancer KRAS_G12V BRD4 194 88 Tumor Type:overall -0.88 -2.42 0.52 1291.65 1.00 1948 190 84 4 FALSE 0.59
non-small cell lung cancer KRAS_G12V BRD4 169 53 Tumor Type:overall -1.44 -4.71 0.83 1078.96 1.00 3461 168 52 1 FALSE 0.52
uterine cancer KRAS_G12V BRD4 56 70 Tumor Type:overall -5.09 -11.45 -1.00 858.72 1.00 937 56 70 0 FALSE 1.20
colorectal cancer KRAS_G12V ASXL1 73 34 Metastasis -0.91 -2.30 0.09 918.05 1.00 773 72 33 1 TRUE 0.83
colorectal cancer KRAS_G12V ASXL1 121 75 Primary -0.76 -1.83 0.12 998.31 1.00 1158 117 71 4 TRUE 0.87
non-small cell lung cancer KRAS_G12V ASXL1 50 44 Metastasis 0.00 -1.79 1.12 1400.30 1.00 1302 49 43 1 TRUE 0.00
non-small cell lung cancer KRAS_G12V ASXL1 119 42 Primary 0.60 -0.45 1.55 1649.65 1.00 2143 114 37 5 TRUE 0.63
uterine cancer KRAS_G12V ASXL1 18 24 Metastasis -1.47 -4.22 0.39 423.99 1.00 342 17 23 1 TRUE 0.67
uterine cancer KRAS_G12V ASXL1 38 36 Primary -1.77 -4.88 0.09 375.11 1.01 608 38 36 0 TRUE 0.73
colorectal cancer KRAS_G12V ASXL1 194 109 Tumor Type:overall -0.82 -2.07 0.25 928.45 1.00 1931 189 104 5 TRUE 0.74
non-small cell lung cancer KRAS_G12V ASXL1 169 86 Tumor Type:overall 0.33 -1.21 1.87 1476.21 1.00 3445 163 80 6 TRUE 0.17
uterine cancer KRAS_G12V ASXL1 56 60 Tumor Type:overall -1.60 -4.38 0.28 399.45 1.00 950 55 59 1 TRUE 0.71
colorectal cancer KRAS_G12V EP300 73 38 Metastasis -0.70 -1.83 0.51 985.13 1.00 776 70 35 3 TRUE 0.63
colorectal cancer KRAS_G12V EP300 121 87 Primary -1.12 -2.44 -0.20 1271.44 1.00 1153 119 85 2 TRUE 1.33
non-small cell lung cancer KRAS_G12V EP300 51 57 Metastasis -0.53 -1.97 0.77 727.30 1.00 1282 49 55 2 TRUE 0.33
non-small cell lung cancer KRAS_G12V EP300 119 51 Primary -0.86 -2.57 0.44 980.73 1.00 2134 118 50 1 TRUE 0.56
uterine cancer KRAS_G12V EP300 18 30 Metastasis -0.09 -1.31 0.97 1171.89 1.00 336 16 28 2 TRUE 0.06
uterine cancer KRAS_G12V EP300 39 73 Primary -0.24 -1.37 0.71 987.75 1.00 586 36 70 3 TRUE 0.19
colorectal cancer KRAS_G12V EP300 194 125 Tumor Type:overall -0.90 -2.34 0.43 1327.31 1.00 1929 189 120 5 TRUE 0.77
non-small cell lung cancer KRAS_G12V EP300 170 108 Tumor Type:overall -0.72 -2.52 0.77 1189.47 1.00 3416 167 105 3 TRUE 0.38
uterine cancer KRAS_G12V EP300 57 103 Tumor Type:overall -0.18 -1.44 1.02 1092.34 1.00 922 52 98 5 TRUE 0.11
colorectal cancer KRAS_G12V ERBB4 81 50 Metastasis -0.38 -1.28 0.56 953.50 1.00 830 76 45 5 TRUE 0.40
colorectal cancer KRAS_G12V ERBB4 136 88 Primary -0.65 -1.64 0.10 1192.76 1.00 1293 133 85 3 TRUE 0.87
non-small cell lung cancer KRAS_G12V ERBB4 53 88 Metastasis 0.02 -1.06 0.99 1167.33 1.00 1309 48 83 5 TRUE 0.02
non-small cell lung cancer KRAS_G12V ERBB4 124 105 Primary -0.68 -2.04 0.26 833.96 1.00 2161 122 103 2 TRUE 0.60
colorectal cancer KRAS_G12V ERBB4 217 138 Tumor Type:overall -0.53 -1.54 0.34 1285.93 1.00 2123 209 130 8 TRUE 0.55
non-small cell lung cancer KRAS_G12V ERBB4 177 193 Tumor Type:overall -0.30 -1.61 1.06 1223.28 1.00 3470 170 186 7 TRUE 0.18
colorectal cancer KRAS_G12V MDC1 73 13 Metastasis -2.60 -6.64 -0.30 1125.96 1.00 792 73 13 0 FALSE 0.94
colorectal cancer KRAS_G12V MDC1 121 52 Primary -2.29 -4.86 -0.46 1188.79 1.00 1177 120 51 1 FALSE 1.34
non-small cell lung cancer KRAS_G12V MDC1 51 60 Metastasis -0.23 -1.69 0.93 1488.16 1.00 1284 49 58 2 FALSE 0.13
non-small cell lung cancer KRAS_G12V MDC1 119 35 Primary -0.16 -1.60 1.04 1504.35 1.00 2146 117 33 2 FALSE 0.09
colorectal cancer KRAS_G12V MDC1 194 65 Tumor Type:overall -2.38 -5.68 0.07 1168.84 1.00 1969 193 64 1 FALSE 1.01
non-small cell lung cancer KRAS_G12V MDC1 170 95 Tumor Type:overall -0.18 -1.95 1.45 1401.49 1.00 3430 166 91 4 FALSE 0.08
colorectal cancer KRAS_G12V RECQL4 73 20 Metastasis -2.81 -6.03 -0.62 1156.11 1.00 788 73 20 0 TRUE 1.28
colorectal cancer KRAS_G12V RECQL4 121 61 Primary -2.52 -5.36 -0.70 1011.41 1.00 1167 120 60 1 TRUE 1.47
non-small cell lung cancer KRAS_G12V RECQL4 50 23 Metastasis -0.23 -2.15 1.45 667.12 1.00 1311 48 21 2 TRUE 0.09
non-small cell lung cancer KRAS_G12V RECQL4 119 41 Primary -1.32 -5.08 0.51 1002.86 1.00 2141 119 41 0 TRUE 0.39
colorectal cancer KRAS_G12V RECQL4 194 81 Tumor Type:overall -2.62 -5.72 -0.51 1068.09 1.00 1955 193 80 1 TRUE 1.30
non-small cell lung cancer KRAS_G12V RECQL4 169 64 Tumor Type:overall -0.72 -3.32 1.20 1388.65 1.00 3452 167 62 2 TRUE 0.26
colorectal cancer KRAS_G12V MED12 73 28 Metastasis -0.21 -1.35 0.86 1291.85 1.00 786 70 25 3 TRUE 0.15
colorectal cancer KRAS_G12V MED12 121 80 Primary -0.56 -1.62 0.25 1386.67 1.00 1153 117 76 4 TRUE 0.65
non-small cell lung cancer KRAS_G12V MED12 50 57 Metastasis -0.51 -1.76 0.61 1542.94 1.00 1281 48 55 2 TRUE 0.41
non-small cell lung cancer KRAS_G12V MED12 119 119 Primary -0.69 -1.79 0.19 1547.24 1.00 2073 116 116 3 TRUE 0.76
uterine cancer KRAS_G12V MED12 18 38 Metastasis -0.58 -1.97 0.77 1379.76 1.00 330 16 36 2 TRUE 0.42
uterine cancer KRAS_G12V MED12 38 102 Primary -0.90 -2.20 0.10 1289.88 1.00 561 36 100 2 TRUE 0.88
colorectal cancer KRAS_G12V MED12 194 108 Tumor Type:overall -0.38 -1.70 0.99 1310.82 1.00 1939 187 101 7 TRUE 0.25
non-small cell lung cancer KRAS_G12V MED12 169 176 Tumor Type:overall -0.60 -2.04 0.53 1469.60 1.00 3354 164 171 5 TRUE 0.44
uterine cancer KRAS_G12V MED12 56 140 Tumor Type:overall -0.72 -2.17 0.66 1202.31 1.00 891 52 136 4 TRUE 0.49
colorectal cancer KRAS_G12V ERCC5 73 14 Metastasis -1.22 -4.30 0.39 1248.16 1.00 792 73 14 0 TRUE 0.50
colorectal cancer KRAS_G12V ERCC5 121 44 Primary -0.69 -2.12 0.40 1120.77 1.00 1182 118 41 3 TRUE 0.55
non-small cell lung cancer KRAS_G12V ERCC5 50 30 Metastasis -5.03 -11.40 -0.76 1130.01 1.00 1303 50 30 0 TRUE 1.10
non-small cell lung cancer KRAS_G12V ERCC5 119 43 Primary -5.11 -11.75 -0.98 1145.37 1.00 2141 119 43 0 TRUE 1.12
uterine cancer KRAS_G12V ERCC5 18 15 Metastasis -1.73 -5.21 0.33 879.67 1.00 347 18 15 0 TRUE 0.66
uterine cancer KRAS_G12V ERCC5 38 37 Primary -1.51 -4.41 0.34 785.67 1.00 610 37 36 1 TRUE 0.65
colorectal cancer KRAS_G12V ERCC5 194 58 Tumor Type:overall -0.92 -3.02 0.64 1280.80 1.00 1974 191 55 3 TRUE 0.47
non-small cell lung cancer KRAS_G12V ERCC5 169 73 Tumor Type:overall -4.99 -11.37 -0.88 1118.56 1.00 3444 169 73 0 TRUE 1.10
uterine cancer KRAS_G12V ERCC5 56 52 Tumor Type:overall -1.61 -4.74 0.48 846.02 1.00 957 55 51 1 TRUE 0.62
colorectal cancer KRAS_G12V PIK3CD 73 24 Metastasis -2.12 -4.65 -0.30 345.42 1.02 785 72 23 1 FALSE 1.22
colorectal cancer KRAS_G12V PIK3CD 121 45 Primary -2.38 -5.22 -0.57 88.36 1.04 1177 121 45 0 FALSE 1.34
colorectal cancer KRAS_G12V PIK3CD 194 69 Tumor Type:overall -2.22 -5.00 -0.38 218.38 1.03 1962 193 68 1 FALSE 1.29
colorectal cancer KRAS_G12V BRCA1 73 17 Metastasis -1.36 -3.46 0.46 1386.93 1.00 789 72 16 1 TRUE 0.78
colorectal cancer KRAS_G12V BRCA1 121 62 Primary -1.75 -3.76 -0.30 1345.23 1.00 1173 120 61 1 TRUE 1.32
non-small cell lung cancer KRAS_G12V BRCA1 50 41 Metastasis -0.37 -2.04 0.84 51.00 1.08 1294 48 39 2 TRUE 0.22
non-small cell lung cancer KRAS_G12V BRCA1 119 56 Primary -0.65 -2.27 0.38 18.10 1.16 2128 118 55 1 TRUE 0.40
colorectal cancer KRAS_G12V BRCA1 194 79 Tumor Type:overall -1.51 -3.50 0.40 1350.01 1.00 1962 192 77 2 TRUE 0.86
non-small cell lung cancer KRAS_G12V BRCA1 169 97 Tumor Type:overall -0.49 -2.10 0.92 40.82 1.09 3422 166 94 3 TRUE 0.26
colorectal cancer KRAS_G12V RBM10 73 22 Metastasis -1.69 -4.02 -0.19 1230.43 1.00 783 73 22 0 FALSE 0.99
colorectal cancer KRAS_G12V RBM10 121 50 Primary -1.43 -3.31 -0.14 1184.52 1.00 1178 119 48 2 FALSE 1.10
non-small cell lung cancer KRAS_G12V RBM10 50 122 Metastasis -0.05 -0.88 0.65 1458.85 1.00 1220 46 118 4 FALSE 0.04
non-small cell lung cancer KRAS_G12V RBM10 119 261 Primary 0.10 -0.44 0.61 1587.11 1.00 1947 104 246 15 FALSE 0.14
uterine cancer KRAS_G12V RBM10 38 46 Primary -0.48 -2.33 0.97 1205.02 1.00 603 36 44 2 FALSE 0.25
colorectal cancer KRAS_G12V RBM10 194 72 Tumor Type:overall -1.53 -3.67 0.00 1308.35 1.00 1961 192 70 2 FALSE 1.04
non-small cell lung cancer KRAS_G12V RBM10 169 383 Tumor Type:overall 0.01 -0.99 0.86 1493.71 1.00 3167 150 364 19 FALSE 0.01
uterine cancer KRAS_G12V RBM10 38 46 Tumor Type:overall -0.36 -4.55 4.16 1371.91 1.00 603 36 44 2 FALSE 0.06
colorectal cancer KRAS_G12V TSC1 73 16 Metastasis -1.40 -4.38 0.22 1189.44 1.00 792 73 16 0 TRUE 0.63
colorectal cancer KRAS_G12V TSC1 121 51 Primary -0.94 -2.15 0.26 207.62 1.02 1180 118 48 3 TRUE 0.92
non-small cell lung cancer KRAS_G12V TSC1 50 25 Metastasis 0.42 -1.04 1.94 35.88 1.08 1310 47 22 3 TRUE 0.20
non-small cell lung cancer KRAS_G12V TSC1 119 32 Primary -0.98 -4.75 0.88 927.33 1.01 2148 119 32 0 TRUE 0.29
uterine cancer KRAS_G12V TSC1 18 16 Metastasis -0.23 -1.94 1.20 1416.77 1.00 349 17 15 1 TRUE 0.11
uterine cancer KRAS_G12V TSC1 38 46 Primary -0.33 -1.78 0.73 1309.34 1.00 602 36 44 2 TRUE 0.21
colorectal cancer KRAS_G12V TSC1 194 67 Tumor Type:overall -1.16 -3.23 0.43 1433.58 1.00 1972 191 64 3 TRUE 0.64
non-small cell lung cancer KRAS_G12V TSC1 169 57 Tumor Type:overall -0.22 -2.58 1.76 522.98 1.01 3458 166 54 3 TRUE 0.08
uterine cancer KRAS_G12V TSC1 56 62 Tumor Type:overall -0.28 -1.86 1.13 1416.64 1.00 951 53 59 3 TRUE 0.14
colorectal cancer KRAS_G12V FLCN 73 18 Metastasis -1.11 -3.13 0.34 883.28 1.00 791 72 17 1 TRUE 0.71
colorectal cancer KRAS_G12V FLCN 121 36 Primary -1.18 -3.12 0.18 868.32 1.00 1187 120 35 1 TRUE 0.80
colorectal cancer KRAS_G12V FLCN 194 54 Tumor Type:overall -1.14 -3.08 0.34 931.45 1.00 1978 192 52 2 TRUE 0.71
colorectal cancer KRAS_G12V NF1 73 37 Metastasis -1.32 -3.06 0.07 1156.73 1.00 776 71 35 2 TRUE 0.98
colorectal cancer KRAS_G12V NF1 121 105 Primary -1.98 -3.75 -0.70 1217.60 1.00 1145 120 104 1 TRUE 1.93
non-small cell lung cancer KRAS_G12V NF1 50 125 Metastasis -0.64 -1.68 0.18 1291.11 1.00 1227 48 123 2 TRUE 0.73
non-small cell lung cancer KRAS_G12V NF1 120 190 Primary -0.42 -1.19 0.27 1271.16 1.00 2023 112 182 8 TRUE 0.59
uterine cancer KRAS_G12V NF1 18 30 Metastasis -5.69 -12.57 -1.22 647.95 1.00 338 18 30 0 TRUE 1.30
uterine cancer KRAS_G12V NF1 38 93 Primary -5.77 -12.66 -1.48 686.54 1.00 580 38 93 0 TRUE 1.38
colorectal cancer KRAS_G12V NF1 194 142 Tumor Type:overall -1.59 -3.45 0.21 1510.23 1.00 1921 191 139 3 TRUE 1.03
non-small cell lung cancer KRAS_G12V NF1 170 315 Tumor Type:overall -0.54 -1.68 0.36 1375.16 1.00 3250 160 305 10 TRUE 0.51
uterine cancer KRAS_G12V NF1 56 123 Tumor Type:overall -5.59 -12.39 -1.29 622.09 1.00 918 56 123 0 TRUE 1.32
colorectal cancer KRAS_G12V FLT1 73 20 Metastasis -2.78 -6.29 -0.56 1096.07 1.00 788 73 20 0 FALSE 1.22
colorectal cancer KRAS_G12V FLT1 121 62 Primary -2.55 -5.40 -0.71 1038.42 1.00 1170 120 61 1 FALSE 1.45
non-small cell lung cancer KRAS_G12V FLT1 50 52 Metastasis -0.07 -1.63 0.90 1346.00 1.00 1286 49 51 1 FALSE 0.04
non-small cell lung cancer KRAS_G12V FLT1 119 84 Primary 0.27 -0.62 1.03 997.91 1.00 2109 112 77 7 FALSE 0.30
uterine cancer KRAS_G12V FLT1 18 13 Metastasis -5.01 -12.24 -0.87 246.45 1.00 348 18 13 0 FALSE 1.07
uterine cancer KRAS_G12V FLT1 38 43 Primary -5.08 -12.27 -1.06 244.56 1.00 604 38 43 0 FALSE 1.09
colorectal cancer KRAS_G12V FLT1 194 82 Tumor Type:overall -2.62 -5.58 -0.40 986.05 1.00 1958 193 81 1 FALSE 1.27
non-small cell lung cancer KRAS_G12V FLT1 169 136 Tumor Type:overall 0.09 -1.28 1.05 1139.07 1.00 3395 161 128 8 FALSE 0.05
uterine cancer KRAS_G12V FLT1 56 56 Tumor Type:overall -4.95 -12.07 -0.80 232.90 1.00 952 56 56 0 FALSE 1.09
colorectal cancer KRAS_G12V RPTOR 73 19 Metastasis -0.13 -1.53 0.88 1475.67 1.00 791 72 18 1 FALSE 0.08
colorectal cancer KRAS_G12V RPTOR 121 51 Primary 0.13 -0.71 0.92 1392.44 1.00 1177 115 45 6 FALSE 0.12
non-small cell lung cancer KRAS_G12V RPTOR 51 27 Metastasis 1.30 0.07 2.47 897.45 1.00 1310 46 22 5 FALSE 1.49
non-small cell lung cancer KRAS_G12V RPTOR 119 38 Primary -0.03 -1.87 1.25 1216.39 1.00 2143 118 37 1 FALSE 0.01
colorectal cancer KRAS_G12V RPTOR 194 70 Tumor Type:overall -0.01 -1.39 1.16 1444.39 1.00 1968 187 63 7 FALSE 0.00
non-small cell lung cancer KRAS_G12V RPTOR 170 65 Tumor Type:overall 0.63 -1.58 2.40 1492.75 1.00 3453 164 59 6 FALSE 0.29
colorectal cancer KRAS_G12V RASA1 73 17 Metastasis 0.15 -1.52 1.63 1451.95 1.00 793 70 14 3 FALSE 0.07
colorectal cancer KRAS_G12V RASA1 121 56 Primary -1.24 -3.10 0.10 1339.97 1.00 1179 120 55 1 FALSE 0.87
non-small cell lung cancer KRAS_G12V RASA1 50 38 Metastasis -0.41 -2.06 0.93 1097.13 1.00 1297 48 36 2 FALSE 0.24
non-small cell lung cancer KRAS_G12V RASA1 119 60 Primary -0.76 -2.39 0.43 1276.82 1.00 2121 118 59 1 FALSE 0.54
uterine cancer KRAS_G12V RASA1 18 21 Metastasis -1.04 -3.31 0.77 1340.07 1.00 342 17 20 1 FALSE 0.49
uterine cancer KRAS_G12V RASA1 38 84 Primary -1.51 -3.38 -0.13 1387.22 1.00 588 37 83 1 FALSE 1.15
colorectal cancer KRAS_G12V RASA1 194 73 Tumor Type:overall -0.54 -2.74 1.41 1281.83 1.00 1972 190 69 4 FALSE 0.23
non-small cell lung cancer KRAS_G12V RASA1 169 98 Tumor Type:overall -0.58 -2.28 0.85 1305.49 1.00 3418 166 95 3 FALSE 0.33
uterine cancer KRAS_G12V RASA1 56 105 Tumor Type:overall -1.25 -3.48 0.75 1407.95 1.00 930 54 103 2 FALSE 0.60
colorectal cancer KRAS_G12V EPHA5 73 43 Metastasis -0.74 -1.83 0.25 1449.13 1.00 768 70 40 3 FALSE 0.77
colorectal cancer KRAS_G12V EPHA5 121 101 Primary -1.03 -2.11 -0.19 1585.69 1.00 1144 118 98 3 FALSE 1.39
non-small cell lung cancer KRAS_G12V EPHA5 50 108 Metastasis 0.27 -0.50 0.99 1256.73 1.00 1239 44 102 6 FALSE 0.33
non-small cell lung cancer KRAS_G12V EPHA5 120 152 Primary 0.11 -0.53 0.68 1306.02 1.00 2049 112 144 8 FALSE 0.13
uterine cancer KRAS_G12V EPHA5 18 24 Metastasis -1.18 -4.28 0.44 762.49 1.01 345 18 24 0 FALSE 0.41
uterine cancer KRAS_G12V EPHA5 38 74 Primary -0.66 -2.13 0.41 1101.87 1.00 587 35 71 3 FALSE 0.52
colorectal cancer KRAS_G12V EPHA5 194 144 Tumor Type:overall -0.88 -2.05 0.27 1665.05 1.00 1912 188 138 6 FALSE 0.83
non-small cell lung cancer KRAS_G12V EPHA5 170 260 Tumor Type:overall 0.19 -0.69 1.08 1390.28 1.00 3288 156 246 14 FALSE 0.17
uterine cancer KRAS_G12V EPHA5 56 98 Tumor Type:overall -0.88 -3.01 0.73 1267.82 1.01 932 53 95 3 FALSE 0.46
colorectal cancer KRAS_G12V AR 73 21 Metastasis -0.60 -2.39 0.70 1396.24 1.00 785 72 20 1 TRUE 0.36
colorectal cancer KRAS_G12V AR 121 95 Primary -0.30 -1.12 0.44 1568.27 1.00 1144 114 88 7 TRUE 0.34
non-small cell lung cancer KRAS_G12V AR 50 39 Metastasis 0.39 -0.66 1.41 1475.44 1.00 1299 47 36 3 TRUE 0.35
non-small cell lung cancer KRAS_G12V AR 119 71 Primary 0.22 -0.69 1.01 1203.80 1.00 2118 115 67 4 TRUE 0.22
uterine cancer KRAS_G12V AR 18 17 Metastasis -0.32 -2.08 1.14 1413.13 1.00 345 17 16 1 TRUE 0.16
uterine cancer KRAS_G12V AR 39 48 Primary -0.39 -1.78 0.76 1253.90 1.00 599 37 46 2 TRUE 0.26
colorectal cancer KRAS_G12V AR 194 116 Tumor Type:overall -0.40 -2.14 1.15 1475.76 1.00 1929 186 108 8 TRUE 0.20
non-small cell lung cancer KRAS_G12V AR 169 110 Tumor Type:overall 0.29 -0.86 1.26 1515.39 1.00 3417 162 103 7 TRUE 0.23
uterine cancer KRAS_G12V AR 57 65 Tumor Type:overall -0.37 -2.00 1.01 1395.54 1.00 944 54 62 3 TRUE 0.20
colorectal cancer KRAS_G12V GNAS 81 20 Metastasis -0.24 -1.75 0.82 1432.54 1.00 853 80 19 1 TRUE 0.15
colorectal cancer KRAS_G12V GNAS 135 55 Primary 0.03 -0.88 0.81 1259.91 1.00 1318 129 49 6 TRUE 0.02
pancreatic cancer KRAS_G12V GNAS 129 15 Metastasis -0.53 -1.77 0.45 1460.60 1.00 462 127 13 2 TRUE 0.47
pancreatic cancer KRAS_G12V GNAS 257 47 Primary -0.29 -0.98 0.31 1330.99 1.00 632 246 36 11 TRUE 0.40
colorectal cancer KRAS_G12V GNAS 216 75 Tumor Type:overall -0.11 -1.41 1.07 1393.30 1.00 2171 209 68 7 TRUE 0.06
pancreatic cancer KRAS_G12V GNAS 386 62 Tumor Type:overall -0.42 -1.83 0.85 1540.52 1.00 1094 373 49 13 TRUE 0.27
colorectal cancer KRAS_G12V ASXL2 73 15 Metastasis -1.24 -3.38 0.63 1401.28 1.00 793 72 14 1 FALSE 0.67
colorectal cancer KRAS_G12V ASXL2 121 56 Primary -1.63 -3.51 -0.26 1430.86 1.00 1183 120 55 1 FALSE 1.23
non-small cell lung cancer KRAS_G12V ASXL2 50 29 Metastasis -4.76 -11.37 -0.77 445.86 1.01 1304 50 29 0 FALSE 1.03
non-small cell lung cancer KRAS_G12V ASXL2 119 34 Primary -4.82 -11.95 -0.89 639.04 1.01 2147 119 34 0 FALSE 1.03
colorectal cancer KRAS_G12V ASXL2 194 71 Tumor Type:overall -1.39 -3.56 0.59 1178.54 1.00 1976 192 69 2 FALSE 0.76
non-small cell lung cancer KRAS_G12V ASXL2 169 63 Tumor Type:overall -4.72 -11.53 -0.66 567.52 1.01 3451 169 63 0 FALSE 1.02
colorectal cancer KRAS_G12V SF3B1 73 21 Metastasis -1.43 -3.85 -0.14 31.84 1.10 793 73 21 0 TRUE 0.75
colorectal cancer KRAS_G12V SF3B1 121 49 Primary -1.21 -3.01 -0.18 26.43 1.13 1180 119 47 2 TRUE 0.93
non-small cell lung cancer KRAS_G12V SF3B1 50 33 Metastasis -0.51 -3.99 0.97 1064.02 1.00 1299 50 33 0 TRUE 0.16
non-small cell lung cancer KRAS_G12V SF3B1 119 54 Primary 0.28 -0.85 1.14 1173.31 1.00 2135 114 49 5 TRUE 0.24
colorectal cancer KRAS_G12V SF3B1 194 70 Tumor Type:overall -1.31 -3.42 -0.07 32.01 1.11 1973 192 68 2 TRUE 0.81
non-small cell lung cancer KRAS_G12V SF3B1 169 87 Tumor Type:overall -0.11 -2.53 1.25 1476.33 1.00 3434 164 82 5 TRUE 0.04
colorectal cancer KRAS_G12V MLH1 81 12 Metastasis -1.64 -4.52 0.70 1294.23 1.00 861 80 11 1 TRUE 0.65
colorectal cancer KRAS_G12V MLH1 135 44 Primary -2.60 -6.04 -0.40 1329.36 1.00 1327 135 44 0 TRUE 1.11
colorectal cancer KRAS_G12V MLH1 216 56 Tumor Type:overall -2.03 -5.02 0.46 1395.73 1.00 2188 215 55 1 TRUE 0.83
colorectal cancer KRAS_G12V ROS1 73 33 Metastasis -2.88 -5.82 -0.97 620.52 1.00 778 73 33 0 TRUE 1.65
colorectal cancer KRAS_G12V ROS1 121 70 Primary -2.71 -5.29 -0.93 504.42 1.00 1167 120 69 1 TRUE 1.76
non-small cell lung cancer KRAS_G12V ROS1 50 35 Metastasis -5.26 -11.87 -1.12 1322.17 1.00 1297 50 35 0 TRUE 1.22
non-small cell lung cancer KRAS_G12V ROS1 119 76 Primary -5.25 -11.80 -1.34 1150.30 1.00 2108 119 76 0 TRUE 1.28
uterine cancer KRAS_G12V ROS1 18 19 Metastasis -0.93 -3.08 0.92 1427.56 1.00 346 17 18 1 TRUE 0.44
uterine cancer KRAS_G12V ROS1 38 81 Primary -1.45 -3.43 0.02 1297.01 1.00 602 37 80 1 TRUE 0.99
colorectal cancer KRAS_G12V ROS1 194 103 Tumor Type:overall -2.78 -5.48 -0.83 613.65 1.00 1945 193 102 1 TRUE 1.66
non-small cell lung cancer KRAS_G12V ROS1 169 111 Tumor Type:overall -5.16 -11.31 -1.16 1247.27 1.00 3405 169 111 0 TRUE 1.25
uterine cancer KRAS_G12V ROS1 56 100 Tumor Type:overall -1.17 -3.57 0.95 1435.53 1.00 948 54 98 2 TRUE 0.56
colorectal cancer KRAS_G12V PIK3R2 121 42 Primary -0.49 -1.76 0.69 221.64 1.03 1184 118 39 3 FALSE 0.39
colorectal cancer KRAS_G12V PIK3R2 121 42 Tumor Type:overall -0.50 -4.17 3.47 1123.51 1.00 1184 118 39 3 FALSE 0.11
colorectal cancer KRAS_G12V FLT3 81 13 Metastasis -0.04 -1.42 1.32 1395.65 1.00 864 79 11 2 TRUE 0.02
colorectal cancer KRAS_G12V FLT3 135 39 Primary -0.39 -1.82 0.66 1434.55 1.00 1331 133 37 2 TRUE 0.27
non-small cell lung cancer KRAS_G12V FLT3 52 41 Metastasis 0.24 -1.06 1.46 1467.82 1.00 1345 49 38 3 TRUE 0.15
non-small cell lung cancer KRAS_G12V FLT3 124 40 Primary -0.40 -2.07 0.82 1450.03 1.00 2211 123 39 1 TRUE 0.22
uterine cancer KRAS_G12V FLT3 19 19 Metastasis -5.28 -11.34 -0.89 140.53 1.01 366 19 19 0 TRUE 1.24
uterine cancer KRAS_G12V FLT3 45 42 Primary -5.31 -11.37 -1.11 135.15 1.01 694 45 42 0 TRUE 1.27
colorectal cancer KRAS_G12V FLT3 216 52 Tumor Type:overall -0.20 -1.72 1.28 1577.34 1.00 2195 212 48 4 TRUE 0.10
non-small cell lung cancer KRAS_G12V FLT3 176 81 Tumor Type:overall -0.06 -1.72 1.38 1581.32 1.00 3556 172 77 4 TRUE 0.03
uterine cancer KRAS_G12V FLT3 64 61 Tumor Type:overall -5.26 -11.27 -1.05 125.10 1.01 1060 64 61 0 TRUE 1.26
colorectal cancer KRAS_G12V MSH2 73 22 Metastasis -0.62 -2.16 0.55 1157.19 1.00 789 72 21 1 TRUE 0.45
colorectal cancer KRAS_G12V MSH2 122 61 Primary -0.50 -1.71 0.42 905.03 1.01 1178 118 57 4 TRUE 0.45
non-small cell lung cancer KRAS_G12V MSH2 50 24 Metastasis -0.51 -2.66 0.93 900.93 1.00 1312 49 23 1 TRUE 0.25
non-small cell lung cancer KRAS_G12V MSH2 119 32 Primary -0.60 -2.60 0.82 1120.97 1.00 2149 118 31 1 TRUE 0.32
uterine cancer KRAS_G12V MSH2 18 15 Metastasis -2.06 -5.85 0.26 1030.11 1.00 347 18 15 0 TRUE 0.74
uterine cancer KRAS_G12V MSH2 38 51 Primary -1.84 -5.08 0.08 915.49 1.00 601 37 50 1 TRUE 0.84
colorectal cancer KRAS_G12V MSH2 195 83 Tumor Type:overall -0.56 -2.10 0.75 1357.66 1.00 1967 190 78 5 TRUE 0.35
non-small cell lung cancer KRAS_G12V MSH2 169 56 Tumor Type:overall -0.54 -2.57 0.94 928.56 1.00 3461 167 54 2 TRUE 0.26
uterine cancer KRAS_G12V MSH2 56 66 Tumor Type:overall -1.93 -5.42 0.34 970.26 1.00 948 55 65 1 TRUE 0.77
non-small cell lung cancer KRAS_G12V DIS3 50 27 Metastasis 0.28 -1.07 1.40 1195.18 1.00 1307 48 25 2 FALSE 0.19
non-small cell lung cancer KRAS_G12V DIS3 119 38 Primary 0.11 -1.36 1.13 1063.33 1.00 2145 117 36 2 FALSE 0.07
non-small cell lung cancer KRAS_G12V DIS3 169 65 Tumor Type:overall 0.21 -1.24 1.41 1092.46 1.00 3452 165 61 4 FALSE 0.12
colorectal cancer KRAS_G12V AXL 73 22 Metastasis -2.08 -5.02 -0.22 1203.31 1.00 787 73 22 0 FALSE 1.00
colorectal cancer KRAS_G12V AXL 121 66 Primary -1.62 -3.43 -0.26 1151.04 1.00 1166 119 64 2 FALSE 1.28
colorectal cancer KRAS_G12V AXL 194 88 Tumor Type:overall -1.85 -4.24 -0.10 1121.84 1.00 1953 192 86 2 FALSE 1.07
pancreatic cancer KRAS_G12V DAXX 126 26 Metastasis -1.76 -3.32 -0.53 1204.06 1.00 431 124 24 2 TRUE 1.85
pancreatic cancer KRAS_G12V DAXX 249 27 Primary -2.02 -3.67 -0.80 1115.03 1.00 621 248 26 1 TRUE 2.18
pancreatic cancer KRAS_G12V DAXX 375 53 Tumor Type:overall -1.86 -3.66 -0.42 1067.49 1.00 1052 372 50 3 TRUE 1.69
colorectal cancer KRAS_G12V PIK3CG 73 34 Metastasis -0.31 -1.36 0.53 1221.05 1.00 776 71 32 2 FALSE 0.28
colorectal cancer KRAS_G12V PIK3CG 121 73 Primary -0.22 -1.10 0.47 1109.22 1.00 1164 115 67 6 FALSE 0.24
non-small cell lung cancer KRAS_G12V PIK3CG 50 72 Metastasis 0.04 -0.88 0.83 1355.14 1.00 1270 47 69 3 FALSE 0.03
non-small cell lung cancer KRAS_G12V PIK3CG 119 108 Primary 0.05 -0.73 0.70 1380.43 1.00 2089 113 102 6 FALSE 0.05
uterine cancer KRAS_G12V PIK3CG 18 16 Metastasis -1.08 -4.03 0.78 60.93 1.05 349 17 15 1 FALSE 0.40
uterine cancer KRAS_G12V PIK3CG 38 35 Primary -1.47 -4.87 0.56 81.76 1.04 607 38 35 0 FALSE 0.47
colorectal cancer KRAS_G12V PIK3CG 194 107 Tumor Type:overall -0.27 -1.23 0.57 1079.42 1.00 1940 186 99 8 FALSE 0.26
non-small cell lung cancer KRAS_G12V PIK3CG 169 180 Tumor Type:overall 0.05 -1.00 0.96 1443.97 1.00 3359 160 171 9 FALSE 0.04
uterine cancer KRAS_G12V PIK3CG 56 51 Tumor Type:overall -1.24 -4.33 0.62 66.96 1.04 956 55 50 1 FALSE 0.44
colorectal cancer KRAS_G12V MAP2K4 73 24 Metastasis -1.98 -4.42 -0.27 123.72 1.03 783 72 23 1 TRUE 1.12
colorectal cancer KRAS_G12V MAP2K4 121 39 Primary -2.21 -5.08 -0.57 142.21 1.02 1182 121 39 0 TRUE 1.13
colorectal cancer KRAS_G12V MAP2K4 194 63 Tumor Type:overall -2.06 -4.59 -0.36 141.00 1.03 1965 193 62 1 TRUE 1.15
colorectal cancer KRAS_G12V EGFR 81 16 Metastasis -0.86 -2.55 0.54 1262.85 1.00 859 80 15 1 TRUE 0.54
colorectal cancer KRAS_G12V EGFR 135 50 Primary -0.92 -2.47 0.31 882.69 1.00 1319 133 48 2 TRUE 0.77
non-small cell lung cancer KRAS_G12V EGFR 52 432 Metastasis -3.41 -5.54 -1.77 322.64 1.01 1040 50 430 2 TRUE 3.77
non-small cell lung cancer KRAS_G12V EGFR 124 610 Primary -4.12 -7.20 -2.51 863.65 1.00 1735 124 610 0 TRUE 3.24
colorectal cancer KRAS_G12V EGFR 216 66 Tumor Type:overall -0.86 -2.64 0.75 1213.40 1.00 2178 213 63 3 TRUE 0.50
non-small cell lung cancer KRAS_G12V EGFR 176 1042 Tumor Type:overall -3.70 -6.04 -1.95 702.81 1.01 2775 174 1040 2 TRUE 3.51
colorectal cancer KRAS_G12V ARID1B 73 35 Metastasis -2.06 -5.72 -0.38 1207.37 1.00 775 73 35 0 TRUE 0.86
colorectal cancer KRAS_G12V ARID1B 121 105 Primary -1.24 -2.42 -0.29 1433.92 1.00 1136 117 101 4 TRUE 1.62
non-small cell lung cancer KRAS_G12V ARID1B 50 55 Metastasis 0.03 -1.15 1.01 1350.10 1.00 1283 48 53 2 TRUE 0.02
non-small cell lung cancer KRAS_G12V ARID1B 120 56 Primary 0.15 -0.86 1.02 1426.20 1.00 2128 116 52 4 TRUE 0.12
uterine cancer KRAS_G12V ARID1B 18 35 Metastasis -0.34 -1.30 0.86 22.00 1.13 331 16 33 2 TRUE 0.24
uterine cancer KRAS_G12V ARID1B 39 79 Primary -0.43 -1.41 0.54 28.98 1.11 579 36 76 3 TRUE 0.38
colorectal cancer KRAS_G12V ARID1B 194 140 Tumor Type:overall -1.58 -3.82 -0.12 1454.02 1.00 1911 190 136 4 TRUE 1.01
non-small cell lung cancer KRAS_G12V ARID1B 170 111 Tumor Type:overall 0.08 -1.18 1.29 1515.57 1.00 3411 164 105 6 TRUE 0.04
uterine cancer KRAS_G12V ARID1B 57 114 Tumor Type:overall -0.38 -1.46 0.81 33.57 1.09 910 52 109 5 TRUE 0.26
non-small cell lung cancer KRAS_G12V INSR 50 22 Metastasis -1.68 -5.33 0.53 1089.24 1.00 1310 50 22 0 FALSE 0.58
non-small cell lung cancer KRAS_G12V INSR 119 33 Primary -1.43 -4.68 0.53 1319.22 1.00 2150 118 32 1 FALSE 0.58
uterine cancer KRAS_G12V INSR 18 11 Metastasis -1.88 -5.48 0.40 1085.76 1.00 347 18 11 0 FALSE 0.61
uterine cancer KRAS_G12V INSR 38 45 Primary -1.57 -4.36 0.30 1071.15 1.00 607 37 44 1 FALSE 0.73
non-small cell lung cancer KRAS_G12V INSR 169 55 Tumor Type:overall -1.52 -4.86 0.67 1300.39 1.00 3460 168 54 1 FALSE 0.58
uterine cancer KRAS_G12V INSR 56 56 Tumor Type:overall -1.74 -4.90 0.43 1039.72 1.00 954 55 55 1 FALSE 0.69
non-small cell lung cancer KRAS_G12V NKX2-1 50 18 Metastasis 0.86 -0.89 1.99 1438.07 1.00 1317 49 17 1 TRUE 0.65
non-small cell lung cancer KRAS_G12V NKX2-1 122 57 Primary 1.28 0.57 1.91 1212.91 1.00 2137 112 47 10 TRUE 3.64
non-small cell lung cancer KRAS_G12V NKX2-1 172 75 Tumor Type:overall 1.07 -0.51 2.41 1598.24 1.00 3454 161 64 11 TRUE 0.84
colorectal cancer KRAS_G12V ARID5B 73 15 Metastasis -1.87 -4.78 0.03 1096.12 1.00 791 73 15 0 FALSE 0.93
colorectal cancer KRAS_G12V ARID5B 121 53 Primary -1.42 -3.00 -0.04 1242.27 1.00 1181 119 51 2 FALSE 1.31
uterine cancer KRAS_G12V ARID5B 18 19 Metastasis -1.47 -4.39 0.34 1231.91 1.00 344 18 19 0 FALSE 0.60
uterine cancer KRAS_G12V ARID5B 38 62 Primary -1.03 -2.78 0.30 1030.88 1.00 588 36 60 2 FALSE 0.73
colorectal cancer KRAS_G12V ARID5B 194 68 Tumor Type:overall -1.60 -3.71 0.21 1284.05 1.00 1972 192 66 2 FALSE 0.98
uterine cancer KRAS_G12V ARID5B 56 81 Tumor Type:overall -1.23 -3.51 0.49 1321.79 1.00 932 54 79 2 FALSE 0.64
non-small cell lung cancer KRAS_G12V WT1 50 28 Metastasis -0.65 -3.43 0.88 1224.23 1.00 1305 50 28 0 TRUE 0.25
non-small cell lung cancer KRAS_G12V WT1 119 42 Primary -0.14 -1.66 1.00 1264.27 1.00 2143 116 39 3 TRUE 0.08
non-small cell lung cancer KRAS_G12V WT1 169 70 Tumor Type:overall -0.40 -2.48 1.06 1272.15 1.00 3448 166 67 3 TRUE 0.18
non-small cell lung cancer KRAS_G12V MET 52 56 Metastasis -0.44 -1.80 0.58 1078.66 1.01 1329 51 55 1 TRUE 0.34
non-small cell lung cancer KRAS_G12V MET 124 109 Primary -0.30 -1.32 0.50 1041.57 1.00 2156 119 104 5 TRUE 0.29
uterine cancer KRAS_G12V MET 19 19 Metastasis -5.22 -11.66 -0.31 53.74 1.05 364 19 19 0 TRUE 1.15
uterine cancer KRAS_G12V MET 45 40 Primary -5.24 -11.68 -0.30 44.72 1.06 698 45 40 0 TRUE 1.16
non-small cell lung cancer KRAS_G12V MET 176 165 Tumor Type:overall -0.37 -1.68 0.67 1239.84 1.00 3485 170 159 6 TRUE 0.25
uterine cancer KRAS_G12V MET 64 59 Tumor Type:overall -5.17 -11.43 -0.30 45.47 1.06 1062 64 59 0 TRUE 1.14
non-small cell lung cancer KRAS_G12V PMS1 50 23 Metastasis 0.89 -0.31 1.92 1321.62 1.00 1312 48 21 2 TRUE 0.96
non-small cell lung cancer KRAS_G12V PMS1 119 29 Primary 0.94 -0.09 1.83 995.04 1.00 2154 115 25 4 TRUE 1.26
non-small cell lung cancer KRAS_G12V PMS1 169 52 Tumor Type:overall 0.90 -0.46 2.05 1130.82 1.00 3466 163 46 6 TRUE 0.83
pancreatic cancer KRAS_G12V MEN1 126 33 Metastasis -3.87 -7.21 -1.93 1237.93 1.00 421 126 33 0 TRUE 2.36
pancreatic cancer KRAS_G12V MEN1 249 44 Primary -3.65 -6.43 -1.86 1311.68 1.00 602 248 43 1 TRUE 2.69
pancreatic cancer KRAS_G12V MEN1 375 77 Tumor Type:overall -3.70 -6.75 -1.74 1333.20 1.00 1023 374 76 1 TRUE 2.37
non-small cell lung cancer KRAS_G12V PIK3C3 50 26 Metastasis -0.06 -1.72 1.15 1202.31 1.00 1307 49 25 1 FALSE 0.03
non-small cell lung cancer KRAS_G12V PIK3C3 119 50 Primary -0.01 -1.38 1.00 900.82 1.00 2134 116 47 3 FALSE 0.01
non-small cell lung cancer KRAS_G12V PIK3C3 169 76 Tumor Type:overall -0.04 -1.68 1.26 1232.86 1.00 3441 165 72 4 FALSE 0.02
colorectal cancer KRAS_G12V BRAF 81 79 Metastasis -1.69 -2.96 -0.47 546.82 1.00 799 78 76 3 TRUE 1.99
colorectal cancer KRAS_G12V BRAF 135 174 Primary -2.33 -4.00 -1.26 1210.47 1.00 1199 134 173 1 TRUE 3.13
non-small cell lung cancer KRAS_G12V BRAF 52 72 Metastasis -0.16 -1.06 0.81 713.14 1.00 1311 49 69 3 TRUE 0.13
non-small cell lung cancer KRAS_G12V BRAF 124 121 Primary -0.25 -1.05 0.55 674.65 1.00 2136 119 116 5 TRUE 0.26
colorectal cancer KRAS_G12V BRAF 216 253 Tumor Type:overall -1.96 -3.56 -0.62 1006.94 1.00 1998 212 249 4 TRUE 1.86
non-small cell lung cancer KRAS_G12V BRAF 176 193 Tumor Type:overall -0.19 -1.20 0.80 806.77 1.00 3447 168 185 8 TRUE 0.15
colorectal cancer KRAS_G12V B2M 73 15 Metastasis -2.77 -6.69 -0.22 1567.78 1.00 795 73 15 0 FALSE 1.01
colorectal cancer KRAS_G12V B2M 121 124 Primary -2.14 -3.86 -0.88 1289.83 1.00 1144 119 122 2 FALSE 2.28
colorectal cancer KRAS_G12V B2M 194 139 Tumor Type:overall -2.30 -5.16 0.40 1531.51 1.00 1939 192 137 2 FALSE 0.97
colorectal cancer KRAS_G12V TGFBR1 73 13 Metastasis -0.26 -1.84 1.01 1486.64 1.00 795 72 12 1 FALSE 0.15
colorectal cancer KRAS_G12V TGFBR1 121 38 Primary -0.24 -1.40 0.77 1356.02 1.00 1189 118 35 3 FALSE 0.17
non-small cell lung cancer KRAS_G12V TGFBR1 50 23 Metastasis -0.35 -2.36 1.15 725.03 1.01 1310 49 22 1 FALSE 0.16
non-small cell lung cancer KRAS_G12V TGFBR1 119 28 Primary -0.48 -2.28 0.88 358.06 1.01 2152 118 27 1 FALSE 0.25
colorectal cancer KRAS_G12V TGFBR1 194 51 Tumor Type:overall -0.26 -1.72 1.05 1540.91 1.00 1984 190 47 4 FALSE 0.14
non-small cell lung cancer KRAS_G12V TGFBR1 169 51 Tumor Type:overall -0.40 -2.37 1.13 545.41 1.01 3462 167 49 2 FALSE 0.18
colorectal cancer KRAS_G12V TET2 73 14 Metastasis -2.41 -6.54 -0.10 1328.23 1.00 793 73 14 0 TRUE 0.82
colorectal cancer KRAS_G12V TET2 121 77 Primary -1.71 -3.56 -0.43 1487.71 1.00 1160 119 75 2 TRUE 1.42
non-small cell lung cancer KRAS_G12V TET2 50 38 Metastasis -0.77 -2.62 0.70 1332.26 1.00 1297 49 37 1 TRUE 0.47
non-small cell lung cancer KRAS_G12V TET2 119 43 Primary -0.86 -2.77 0.41 457.12 1.01 2140 118 42 1 TRUE 0.56
uterine cancer KRAS_G12V TET2 18 25 Metastasis -1.92 -5.03 -0.01 608.28 1.01 341 18 25 0 TRUE 0.94
uterine cancer KRAS_G12V TET2 38 41 Primary -1.80 -4.36 0.03 555.57 1.01 603 37 40 1 TRUE 0.96
colorectal cancer KRAS_G12V TET2 194 91 Tumor Type:overall -1.93 -4.69 0.35 1419.40 1.00 1953 192 89 2 TRUE 0.87
non-small cell lung cancer KRAS_G12V TET2 169 81 Tumor Type:overall -0.80 -2.76 0.58 1330.60 1.01 3437 167 79 2 TRUE 0.46
uterine cancer KRAS_G12V TET2 56 66 Tumor Type:overall -1.85 -4.51 0.02 622.18 1.01 944 55 65 1 TRUE 0.94
colorectal cancer KRAS_G12V PDGFRB 121 46 Primary -1.95 -4.66 -0.17 1565.08 1.00 1175 120 45 1 TRUE 1.05
non-small cell lung cancer KRAS_G12V PDGFRB 50 37 Metastasis 0.42 -0.68 1.32 1352.83 1.00 1299 48 35 2 TRUE 0.39
non-small cell lung cancer KRAS_G12V PDGFRB 120 55 Primary 0.49 -0.42 1.25 1486.77 1.00 2135 115 50 5 TRUE 0.59
colorectal cancer KRAS_G12V PDGFRB 121 46 Tumor Type:overall -1.56 -5.81 3.57 1444.62 1.00 1175 120 45 1 TRUE 0.31
non-small cell lung cancer KRAS_G12V PDGFRB 170 92 Tumor Type:overall 0.46 -0.66 1.47 1328.66 1.00 3434 163 85 7 TRUE 0.40
colorectal cancer KRAS_G12V CARD11 73 29 Metastasis -1.08 -2.84 0.23 1561.83 1.00 780 72 28 1 FALSE 0.83
colorectal cancer KRAS_G12V CARD11 121 99 Primary -1.00 -2.12 -0.11 1447.49 1.00 1134 117 95 4 FALSE 1.27
non-small cell lung cancer KRAS_G12V CARD11 50 43 Metastasis -0.90 -2.61 0.41 1051.62 1.00 1291 49 42 1 FALSE 0.63
non-small cell lung cancer KRAS_G12V CARD11 119 87 Primary -0.92 -2.47 0.19 1073.67 1.00 2100 117 85 2 FALSE 0.78
uterine cancer KRAS_G12V CARD11 18 16 Metastasis -0.60 -2.60 0.95 1033.53 1.00 346 17 15 1 FALSE 0.31
uterine cancer KRAS_G12V CARD11 38 39 Primary -0.71 -2.72 0.67 1082.76 1.00 604 37 38 1 FALSE 0.40
colorectal cancer KRAS_G12V CARD11 194 128 Tumor Type:overall -1.04 -2.71 0.43 1377.58 1.00 1914 189 123 5 FALSE 0.74
non-small cell lung cancer KRAS_G12V CARD11 169 130 Tumor Type:overall -0.90 -2.52 0.46 984.20 1.00 3391 166 127 3 FALSE 0.60
uterine cancer KRAS_G12V CARD11 56 55 Tumor Type:overall -0.64 -2.73 0.91 1056.44 1.00 950 54 53 2 FALSE 0.32
colorectal cancer KRAS_G12V DNMT3A 73 11 Metastasis -1.70 -5.10 0.27 1502.27 1.00 794 73 11 0 TRUE 0.63
colorectal cancer KRAS_G12V DNMT3A 121 45 Primary -1.17 -3.03 0.14 1415.23 1.00 1183 119 43 2 TRUE 0.81
non-small cell lung cancer KRAS_G12V DNMT3A 50 27 Metastasis -0.35 -3.55 1.11 1007.48 1.00 1305 50 27 0 TRUE 0.11
non-small cell lung cancer KRAS_G12V DNMT3A 119 50 Primary 0.36 -0.71 1.31 887.96 1.01 2135 114 45 5 TRUE 0.31
colorectal cancer KRAS_G12V DNMT3A 194 56 Tumor Type:overall -1.39 -3.92 0.46 1428.11 1.00 1977 192 54 2 TRUE 0.66
non-small cell lung cancer KRAS_G12V DNMT3A 169 77 Tumor Type:overall 0.04 -2.26 1.39 1012.21 1.00 3440 164 72 5 TRUE 0.01
colorectal cancer KRAS_G12V MSH6 73 23 Metastasis -1.82 -4.97 -0.11 1555.07 1.00 785 73 23 0 TRUE 0.85
colorectal cancer KRAS_G12V MSH6 121 77 Primary -1.26 -2.56 -0.17 1339.78 1.00 1161 118 74 3 TRUE 1.40
uterine cancer KRAS_G12V MSH6 18 22 Metastasis -0.33 -1.92 1.05 1333.85 1.00 344 17 21 1 TRUE 0.18
uterine cancer KRAS_G12V MSH6 38 68 Primary -0.33 -1.55 0.78 1354.62 1.00 591 35 65 3 TRUE 0.23
colorectal cancer KRAS_G12V MSH6 194 100 Tumor Type:overall -1.53 -3.76 0.23 1446.44 1.00 1946 191 97 3 TRUE 0.87
uterine cancer KRAS_G12V MSH6 56 90 Tumor Type:overall -0.34 -2.02 0.98 1421.31 1.00 935 52 86 4 TRUE 0.18
non-small cell lung cancer KRAS_G12V MAX 50 16 Metastasis 0.91 -0.37 2.01 1382.23 1.00 1318 48 14 2 FALSE 0.88
non-small cell lung cancer KRAS_G12V MAX 119 39 Primary 0.80 -0.24 1.69 1292.73 1.00 2145 115 35 4 FALSE 0.99
non-small cell lung cancer KRAS_G12V MAX 169 55 Tumor Type:overall 0.85 -0.38 1.99 1247.43 1.00 3463 163 49 6 FALSE 0.76
non-small cell lung cancer KRAS_G12V INPP4B 50 53 Metastasis -0.25 -1.69 0.78 1383.10 1.00 1285 49 52 1 FALSE 0.16
non-small cell lung cancer KRAS_G12V INPP4B 119 73 Primary 0.03 -0.88 0.89 1312.68 1.00 2117 114 68 5 FALSE 0.02
non-small cell lung cancer KRAS_G12V INPP4B 169 126 Tumor Type:overall -0.12 -1.41 0.99 1407.14 1.00 3402 163 120 6 FALSE 0.07
non-small cell lung cancer KRAS_G12V NFE2L2 50 43 Metastasis -0.94 -3.88 0.45 959.60 1.00 1294 50 43 0 FALSE 0.37
non-small cell lung cancer KRAS_G12V NFE2L2 119 81 Primary -0.40 -1.58 0.55 521.57 1.01 2110 115 77 4 FALSE 0.33
non-small cell lung cancer KRAS_G12V NFE2L2 169 124 Tumor Type:overall -0.65 -2.82 0.80 945.95 1.00 3404 165 120 4 FALSE 0.33
uterine cancer KRAS_G12V SPOP 18 14 Metastasis -1.87 -5.17 0.37 1134.98 1.00 345 18 14 0 FALSE 0.71
uterine cancer KRAS_G12V SPOP 38 44 Primary -1.65 -4.41 0.27 1079.76 1.00 595 37 43 1 FALSE 0.82
uterine cancer KRAS_G12V SPOP 56 58 Tumor Type:overall -1.74 -4.66 0.45 1175.49 1.00 940 55 57 1 FALSE 0.75
colorectal cancer KRAS_G12V SOX9 73 72 Metastasis 0.37 -0.27 1.00 1470.17 1.00 748 64 63 9 FALSE 0.58
colorectal cancer KRAS_G12V SOX9 123 192 Primary 0.21 -0.27 0.68 1413.73 1.00 1064 103 172 20 FALSE 0.42
colorectal cancer KRAS_G12V SOX9 196 264 Tumor Type:overall 0.29 -0.67 1.26 1707.17 1.00 1812 167 235 29 FALSE 0.26
colorectal cancer KRAS_G12V ETV1 73 14 Metastasis -1.54 -4.00 0.25 150.34 1.02 791 73 14 0 TRUE 0.74
colorectal cancer KRAS_G12V ETV1 121 38 Primary -1.23 -2.90 0.20 52.02 1.06 1187 119 36 2 TRUE 0.78
colorectal cancer KRAS_G12V ETV1 194 52 Tumor Type:overall -1.37 -3.34 0.34 91.44 1.03 1978 192 50 2 TRUE 0.73
colorectal cancer KRAS_G12V ARAF 73 18 Metastasis -1.47 -4.09 0.12 1219.83 1.00 787 73 18 0 FALSE 0.74
colorectal cancer KRAS_G12V ARAF 122 37 Primary -1.17 -2.94 0.24 355.08 1.01 1189 120 35 2 FALSE 0.82
non-small cell lung cancer KRAS_G12V ARAF 50 30 Metastasis -1.07 -3.92 0.69 1360.79 1.00 1306 50 30 0 FALSE 0.46
non-small cell lung cancer KRAS_G12V ARAF 119 39 Primary -0.64 -2.42 0.81 1333.41 1.00 2147 117 37 2 FALSE 0.37
colorectal cancer KRAS_G12V ARAF 195 55 Tumor Type:overall -1.29 -3.34 0.21 515.32 1.00 1976 193 53 2 FALSE 0.80
non-small cell lung cancer KRAS_G12V ARAF 169 69 Tumor Type:overall -0.85 -3.12 0.88 1325.65 1.00 3453 167 67 2 FALSE 0.40
non-small cell lung cancer KRAS_G12V JAK2 52 41 Metastasis -0.17 -1.83 1.17 1484.55 1.00 1344 50 39 2 TRUE 0.09
non-small cell lung cancer KRAS_G12V JAK2 124 37 Primary -0.54 -2.29 0.72 1447.09 1.00 2213 123 36 1 TRUE 0.31
non-small cell lung cancer KRAS_G12V JAK2 176 78 Tumor Type:overall -0.35 -2.11 1.26 1333.66 1.00 3557 173 75 3 TRUE 0.16
colorectal cancer KRAS_G12V SMAD2 73 26 Metastasis 0.90 0.01 1.79 1202.45 1.00 787 67 20 6 TRUE 1.39
colorectal cancer KRAS_G12V SMAD2 122 76 Primary 0.44 -0.22 1.07 1446.83 1.00 1161 113 67 9 TRUE 0.71
colorectal cancer KRAS_G12V SMAD2 195 102 Tumor Type:overall 0.65 -0.51 1.89 1175.67 1.00 1948 180 87 15 TRUE 0.57
non-small cell lung cancer KRAS_G12V TP63 50 33 Metastasis -0.11 -1.68 1.27 1474.95 1.00 1301 48 31 2 FALSE 0.05
non-small cell lung cancer KRAS_G12V TP63 119 39 Primary -0.46 -2.36 0.81 1534.17 1.00 2143 118 38 1 FALSE 0.26
non-small cell lung cancer KRAS_G12V TP63 169 72 Tumor Type:overall -0.28 -2.07 1.25 1466.40 1.00 3444 166 69 3 FALSE 0.13
colorectal cancer KRAS_G12V JUN 73 16 Metastasis -1.95 -4.84 0.19 782.28 1.00 791 72 15 1 FALSE 0.90
colorectal cancer KRAS_G12V JUN 121 37 Primary -2.34 -5.40 -0.27 900.28 1.00 1185 121 37 0 FALSE 1.13
colorectal cancer KRAS_G12V JUN 194 53 Tumor Type:overall -2.11 -5.12 0.00 852.14 1.00 1976 193 52 1 FALSE 1.02
colorectal cancer KRAS_G12V DNMT3B 73 15 Metastasis -0.05 -1.42 1.24 1191.81 1.00 793 71 13 2 FALSE 0.02
colorectal cancer KRAS_G12V DNMT3B 122 49 Primary -0.34 -1.52 0.61 1457.24 1.00 1179 119 46 3 FALSE 0.27
colorectal cancer KRAS_G12V DNMT3B 195 64 Tumor Type:overall -0.18 -1.70 1.34 1415.30 1.00 1972 190 59 5 FALSE 0.09
non-small cell lung cancer KRAS_G12V MYOD1 50 25 Metastasis -0.38 -4.18 1.18 1130.52 1.00 1307 50 25 0 FALSE 0.10
non-small cell lung cancer KRAS_G12V MYOD1 119 33 Primary 0.51 -0.75 1.53 1467.22 1.00 2154 115 29 4 FALSE 0.42
non-small cell lung cancer KRAS_G12V MYOD1 169 58 Tumor Type:overall 0.08 -2.40 1.56 1404.76 1.00 3461 165 54 4 FALSE 0.03
colorectal cancer KRAS_G12V FGFR1 81 17 Metastasis -2.10 -5.02 -0.10 1032.89 1.00 857 81 17 0 TRUE 0.95
colorectal cancer KRAS_G12V FGFR1 135 34 Primary -1.94 -4.59 -0.13 1068.72 1.00 1333 134 33 1 TRUE 1.05
colorectal cancer KRAS_G12V FGFR1 216 51 Tumor Type:overall -2.00 -4.70 -0.09 999.62 1.00 2190 215 50 1 TRUE 0.99
colorectal cancer KRAS_G12V MITF 73 14 Metastasis -2.10 -5.42 -0.09 434.12 1.00 791 73 14 0 FALSE 0.89
colorectal cancer KRAS_G12V MITF 121 38 Primary -1.91 -4.53 -0.19 408.61 1.00 1183 120 37 1 FALSE 1.03
colorectal cancer KRAS_G12V MITF 194 52 Tumor Type:overall -1.97 -4.91 0.02 491.69 1.00 1974 193 51 1 FALSE 0.90
non-small cell lung cancer KRAS_G12V BTK 50 28 Metastasis 0.13 -1.34 1.42 1048.65 1.00 1306 48 26 2 TRUE 0.07
non-small cell lung cancer KRAS_G12V BTK 119 32 Primary -0.24 -1.86 1.02 1058.58 1.00 2149 118 31 1 TRUE 0.13
non-small cell lung cancer KRAS_G12V BTK 169 60 Tumor Type:overall -0.06 -1.73 1.33 1274.73 1.00 3455 166 57 3 TRUE 0.03
colorectal cancer KRAS_G12V SH2B3 111 46 Primary -6.27 -15.96 -1.17 905.14 1.00 1080 111 46 0 FALSE 0.57
colorectal cancer KRAS_G12V SH2B3 111 46 Tumor Type:overall -4.41 -11.68 2.60 1077.84 1.00 1080 111 46 0 FALSE 0.67
colorectal cancer KRAS_G12V GLI1 67 24 Metastasis -1.59 -3.50 0.03 1462.65 1.00 702 66 23 1 FALSE 1.13
colorectal cancer KRAS_G12V GLI1 111 63 Primary -1.78 -3.67 -0.43 1053.19 1.00 1066 110 62 1 FALSE 1.52
non-small cell lung cancer KRAS_G12V GLI1 44 37 Metastasis 0.30 -1.19 1.33 1013.81 1.00 1159 43 36 1 FALSE 0.20
non-small cell lung cancer KRAS_G12V GLI1 113 69 Primary 0.67 -0.17 1.41 1277.63 1.00 1911 105 61 8 FALSE 1.02
uterine cancer KRAS_G12V GLI1 14 13 Metastasis -1.78 -5.04 0.43 1221.65 1.00 289 14 13 0 FALSE 0.64
uterine cancer KRAS_G12V GLI1 37 40 Primary -1.60 -4.31 0.24 1021.53 1.00 558 36 39 1 FALSE 0.77
colorectal cancer KRAS_G12V GLI1 178 87 Tumor Type:overall -1.65 -3.72 0.10 1321.65 1.00 1768 176 85 2 FALSE 1.07
non-small cell lung cancer KRAS_G12V GLI1 157 106 Tumor Type:overall 0.48 -0.78 1.51 1314.10 1.00 3070 148 97 9 FALSE 0.37
uterine cancer KRAS_G12V GLI1 51 53 Tumor Type:overall -1.66 -4.48 0.41 1115.64 1.00 847 50 52 1 FALSE 0.72
colorectal cancer KRAS_G12V ZFHX3 67 52 Metastasis -2.35 -5.96 -0.54 1204.10 1.00 686 67 52 0 FALSE 0.97
colorectal cancer KRAS_G12V ZFHX3 113 174 Primary -1.12 -1.97 -0.32 1388.70 1.00 1005 106 167 7 FALSE 2.14
non-small cell lung cancer KRAS_G12V ZFHX3 45 75 Metastasis 0.74 -0.18 1.63 1350.84 1.00 1124 38 68 7 FALSE 0.95
non-small cell lung cancer KRAS_G12V ZFHX3 113 89 Primary -0.21 -1.46 0.72 967.38 1.00 1887 110 86 3 FALSE 0.15
uterine cancer KRAS_G12V ZFHX3 15 65 Metastasis -0.49 -1.53 0.39 1382.57 1.00 259 13 63 2 FALSE 0.47
uterine cancer KRAS_G12V ZFHX3 37 150 Primary -0.47 -1.38 0.31 1083.94 1.00 501 31 144 6 FALSE 0.56
colorectal cancer KRAS_G12V ZFHX3 180 226 Tumor Type:overall -1.67 -4.37 0.14 1171.24 1.00 1691 173 219 7 FALSE 0.92
non-small cell lung cancer KRAS_G12V ZFHX3 158 164 Tumor Type:overall 0.26 -1.22 1.75 1357.59 1.00 3011 148 154 10 FALSE 0.14
uterine cancer KRAS_G12V ZFHX3 52 215 Tumor Type:overall -0.48 -1.60 0.50 1292.29 1.00 760 44 207 8 FALSE 0.43
colorectal cancer KRAS_G12V MST1R 67 19 Metastasis -2.58 -5.92 -0.45 962.08 1.00 707 67 19 0 FALSE 0.90
colorectal cancer KRAS_G12V MST1R 111 54 Primary -2.32 -4.91 -0.52 1060.88 1.00 1078 110 53 1 FALSE 1.37
colorectal cancer KRAS_G12V MST1R 178 73 Tumor Type:overall -2.40 -5.44 -0.40 1135.80 1.00 1785 177 72 1 FALSE 1.22
colorectal cancer KRAS_G12V MGA 67 29 Metastasis 0.12 -0.88 1.12 1459.77 1.00 699 63 25 4 FALSE 0.08
colorectal cancer KRAS_G12V MGA 112 94 Primary -0.47 -1.37 0.31 1351.02 1.00 1046 107 89 5 FALSE 0.55
non-small cell lung cancer KRAS_G12V MGA 44 82 Metastasis 0.05 -1.30 0.89 1461.13 1.00 1128 42 80 2 FALSE 0.03
non-small cell lung cancer KRAS_G12V MGA 113 115 Primary 0.58 -0.08 1.18 1530.54 1.00 1872 101 103 12 FALSE 1.15
uterine cancer KRAS_G12V MGA 14 34 Metastasis -1.38 -3.33 0.18 705.97 1.00 280 13 33 1 FALSE 0.89
uterine cancer KRAS_G12V MGA 37 81 Primary -1.53 -3.42 -0.12 601.33 1.00 543 36 80 1 FALSE 1.14
colorectal cancer KRAS_G12V MGA 179 123 Tumor Type:overall -0.18 -1.56 1.23 1439.08 1.00 1745 170 114 9 FALSE 0.10
non-small cell lung cancer KRAS_G12V MGA 157 197 Tumor Type:overall 0.32 -0.94 1.39 1388.62 1.00 3000 143 183 14 FALSE 0.24
uterine cancer KRAS_G12V MGA 51 115 Tumor Type:overall -1.43 -3.36 0.11 709.03 1.01 823 49 113 2 FALSE 0.89
colorectal cancer KRAS_G12V TCF3 67 13 Metastasis -0.77 -2.55 0.88 1453.77 1.00 713 66 12 1 FALSE 0.42
colorectal cancer KRAS_G12V TCF3 112 55 Primary -1.01 -2.49 0.19 1337.47 1.00 1071 110 53 2 FALSE 0.85
colorectal cancer KRAS_G12V TCF3 179 68 Tumor Type:overall -0.89 -2.86 1.03 1594.75 1.00 1784 176 65 3 FALSE 0.45
colorectal cancer KRAS_G12V KMT2B 27 39 Metastasis -2.02 -5.08 -0.46 1215.25 1.00 313 27 39 0 FALSE 1.00
colorectal cancer KRAS_G12V KMT2B 71 143 Primary -1.34 -2.42 -0.47 1324.23 1.00 611 66 138 5 FALSE 2.13
non-small cell lung cancer KRAS_G12V KMT2B 21 19 Metastasis 0.37 -1.46 2.13 1327.43 1.00 639 19 17 2 FALSE 0.16
non-small cell lung cancer KRAS_G12V KMT2B 70 52 Primary -0.74 -2.56 0.63 1240.76 1.00 1085 69 51 1 FALSE 0.42
colorectal cancer KRAS_G12V KMT2B 98 182 Tumor Type:overall -1.64 -3.85 -0.02 1503.57 1.00 924 93 177 5 FALSE 1.08
non-small cell lung cancer KRAS_G12V KMT2B 91 71 Tumor Type:overall -0.21 -2.52 1.85 1284.81 1.00 1724 88 68 3 FALSE 0.07
colorectal cancer KRAS_G12V TCF7L2 68 97 Metastasis -0.17 -0.89 0.39 1421.19 1.00 639 62 91 6 FALSE 0.22
colorectal cancer KRAS_G12V TCF7L2 114 202 Primary 0.07 -0.41 0.54 1553.48 1.00 956 93 181 21 FALSE 0.11
colorectal cancer KRAS_G12V TCF7L2 182 299 Tumor Type:overall -0.07 -0.82 0.67 1453.84 1.00 1595 155 272 27 FALSE 0.06
colorectal cancer KRAS_G12V MSH3 27 18 Metastasis -2.89 -6.02 -0.68 1089.41 1.00 320 27 18 0 FALSE 1.40
colorectal cancer KRAS_G12V MSH3 69 71 Primary -2.64 -5.20 -0.88 460.00 1.00 642 68 70 1 FALSE 1.71
colorectal cancer KRAS_G12V MSH3 96 89 Tumor Type:overall -2.72 -5.60 -0.60 832.68 1.00 962 95 88 1 FALSE 1.46
colorectal cancer KRAS_G12V ANKRD11 67 36 Metastasis -1.68 -3.43 -0.22 1506.26 1.00 698 66 35 1 FALSE 1.38
colorectal cancer KRAS_G12V ANKRD11 111 110 Primary -1.79 -3.27 -0.65 1591.58 1.00 1038 109 108 2 FALSE 2.10
non-small cell lung cancer KRAS_G12V ANKRD11 44 27 Metastasis -1.08 -3.51 0.49 1427.57 1.00 1167 44 27 0 FALSE 0.52
non-small cell lung cancer KRAS_G12V ANKRD11 113 45 Primary -0.74 -2.54 0.58 1212.26 1.00 1927 111 43 2 FALSE 0.48
uterine cancer KRAS_G12V ANKRD11 14 30 Metastasis -0.20 -1.62 1.00 1173.53 1.00 281 12 28 2 FALSE 0.11
uterine cancer KRAS_G12V ANKRD11 37 60 Primary -0.39 -1.83 0.66 781.20 1.00 547 35 58 2 FALSE 0.28
colorectal cancer KRAS_G12V ANKRD11 178 146 Tumor Type:overall -1.69 -3.51 -0.16 1506.38 1.00 1736 175 143 3 FALSE 1.30
non-small cell lung cancer KRAS_G12V ANKRD11 157 72 Tumor Type:overall -0.89 -2.83 0.66 1437.23 1.00 3094 155 70 2 FALSE 0.48
uterine cancer KRAS_G12V ANKRD11 51 90 Tumor Type:overall -0.30 -1.71 0.90 1130.95 1.00 828 47 86 4 FALSE 0.18
colorectal cancer KRAS_G12V PGR 67 11 Metastasis -1.88 -5.12 0.23 1341.25 1.00 714 67 11 0 FALSE 0.72
colorectal cancer KRAS_G12V PGR 111 52 Primary -1.34 -3.07 0.03 1399.29 1.00 1075 109 50 2 FALSE 1.03
non-small cell lung cancer KRAS_G12V PGR 44 34 Metastasis -5.00 -11.40 -1.01 1170.94 1.00 1157 44 34 0 FALSE 1.22
non-small cell lung cancer KRAS_G12V PGR 113 53 Primary -5.00 -11.44 -1.07 898.50 1.00 1919 113 53 0 FALSE 1.24
uterine cancer KRAS_G12V PGR 37 48 Primary -1.57 -4.33 0.25 1447.31 1.00 547 36 47 1 FALSE 0.74
colorectal cancer KRAS_G12V PGR 178 63 Tumor Type:overall -1.54 -4.00 0.44 1490.94 1.00 1789 176 61 2 FALSE 0.77
non-small cell lung cancer KRAS_G12V PGR 157 87 Tumor Type:overall -4.93 -11.32 -1.00 985.47 1.00 3076 157 87 0 FALSE 1.22
uterine cancer KRAS_G12V PGR 37 48 Tumor Type:overall -1.26 -6.14 3.70 1277.96 1.00 547 36 47 1 FALSE 0.23
colorectal cancer KRAS_G12V PLCG2 67 22 Metastasis -2.00 -5.02 -0.35 1263.51 1.00 704 67 22 0 FALSE 0.91
colorectal cancer KRAS_G12V PLCG2 111 63 Primary -1.60 -3.36 -0.32 1202.58 1.00 1065 109 61 2 FALSE 1.40
non-small cell lung cancer KRAS_G12V PLCG2 44 24 Metastasis -1.34 -4.28 0.82 1076.73 1.00 1169 43 23 1 FALSE 0.54
non-small cell lung cancer KRAS_G12V PLCG2 113 38 Primary -1.90 -5.26 0.03 823.45 1.00 1937 113 38 0 FALSE 0.74
uterine cancer KRAS_G12V PLCG2 14 11 Metastasis -5.06 -11.81 -0.34 962.87 1.00 292 14 11 0 FALSE 1.03
uterine cancer KRAS_G12V PLCG2 37 46 Primary -5.20 -11.85 -0.79 913.91 1.00 557 37 46 0 FALSE 1.10
colorectal cancer KRAS_G12V PLCG2 178 85 Tumor Type:overall -1.78 -4.08 -0.11 1191.00 1.00 1769 176 83 2 FALSE 0.99
non-small cell lung cancer KRAS_G12V PLCG2 157 62 Tumor Type:overall -1.61 -4.63 0.57 952.14 1.00 3106 156 61 1 FALSE 0.67
uterine cancer KRAS_G12V PLCG2 51 57 Tumor Type:overall -5.03 -11.56 -0.47 926.15 1.00 849 51 57 0 FALSE 1.06
colorectal cancer KRAS_G12V POLD1 67 20 Metastasis -1.06 -2.88 0.59 1403.82 1.00 709 66 19 1 TRUE 0.65
colorectal cancer KRAS_G12V POLD1 111 92 Primary -1.19 -2.42 -0.17 1324.94 1.00 1054 108 89 3 TRUE 1.38
non-small cell lung cancer KRAS_G12V POLD1 44 25 Metastasis 0.17 -1.34 1.53 1573.80 1.00 1167 42 23 2 TRUE 0.09
non-small cell lung cancer KRAS_G12V POLD1 113 33 Primary -0.26 -1.91 1.00 1420.68 1.00 1939 112 32 1 TRUE 0.14
colorectal cancer KRAS_G12V POLD1 178 112 Tumor Type:overall -1.12 -3.06 0.70 1469.04 1.00 1763 174 108 4 TRUE 0.63
non-small cell lung cancer KRAS_G12V POLD1 157 58 Tumor Type:overall -0.04 -1.82 1.42 1223.77 1.00 3106 154 55 3 TRUE 0.02
colorectal cancer KRAS_G12V INHBA 67 20 Metastasis 0.34 -0.74 1.42 923.28 1.00 708 63 16 4 FALSE 0.28
colorectal cancer KRAS_G12V INHBA 111 34 Primary 0.02 -1.20 0.94 711.23 1.00 1089 109 32 2 FALSE 0.01
non-small cell lung cancer KRAS_G12V INHBA 44 32 Metastasis -0.90 -2.88 0.60 1300.30 1.00 1164 43 31 1 FALSE 0.51
non-small cell lung cancer KRAS_G12V INHBA 113 55 Primary -1.06 -2.90 0.34 1323.69 1.00 1917 112 54 1 FALSE 0.71
colorectal cancer KRAS_G12V INHBA 178 54 Tumor Type:overall 0.20 -1.04 1.29 915.38 1.00 1797 172 48 6 FALSE 0.13
non-small cell lung cancer KRAS_G12V INHBA 157 87 Tumor Type:overall -0.98 -2.95 0.60 1409.10 1.00 3081 155 85 2 FALSE 0.56
colorectal cancer KRAS_G12V PREX2 27 31 Metastasis -1.29 -3.67 -0.13 102.18 1.05 311 27 31 0 FALSE 0.78
colorectal cancer KRAS_G12V PREX2 69 60 Primary -1.03 -2.29 -0.06 168.35 1.03 653 66 57 3 FALSE 1.06
non-small cell lung cancer KRAS_G12V PREX2 20 42 Metastasis -1.02 -4.82 0.74 1206.16 1.00 619 20 42 0 FALSE 0.31
non-small cell lung cancer KRAS_G12V PREX2 70 63 Primary 0.05 -1.06 1.01 1453.20 1.00 1080 65 58 5 FALSE 0.03
colorectal cancer KRAS_G12V PREX2 96 91 Tumor Type:overall -1.15 -2.91 -0.09 136.43 1.04 964 93 88 3 FALSE 0.91
non-small cell lung cancer KRAS_G12V PREX2 90 105 Tumor Type:overall -0.46 -3.30 1.14 1343.61 1.00 1699 85 100 5 FALSE 0.18
colorectal cancer KRAS_G12V AMER1 73 51 Metastasis 0.46 -0.24 1.10 1467.41 1.00 763 66 44 7 FALSE 0.79
colorectal cancer KRAS_G12V AMER1 121 118 Primary 0.39 -0.18 0.89 1135.90 1.00 1127 107 104 14 FALSE 0.81
non-small cell lung cancer KRAS_G12V AMER1 50 54 Metastasis 0.24 -0.88 1.10 1208.53 1.00 1289 48 52 2 FALSE 0.19
non-small cell lung cancer KRAS_G12V AMER1 120 95 Primary 0.41 -0.35 1.10 1030.37 1.00 2103 112 87 8 FALSE 0.56
uterine cancer KRAS_G12V AMER1 18 14 Metastasis 0.20 -1.66 1.92 396.60 1.01 352 16 12 2 FALSE 0.08
uterine cancer KRAS_G12V AMER1 38 42 Primary -0.49 -2.33 0.78 666.16 1.00 607 37 41 1 FALSE 0.26
colorectal cancer KRAS_G12V AMER1 194 169 Tumor Type:overall 0.42 -0.50 1.26 1520.05 1.00 1890 173 148 21 FALSE 0.50
non-small cell lung cancer KRAS_G12V AMER1 170 149 Tumor Type:overall 0.30 -0.82 1.28 1447.05 1.00 3392 160 139 10 FALSE 0.22
uterine cancer KRAS_G12V AMER1 56 56 Tumor Type:overall -0.16 -2.06 1.71 686.18 1.00 959 53 53 3 FALSE 0.06
colorectal cancer KRAS_G12V HLA-A 111 42 Primary -1.85 -4.52 -0.04 1517.63 1.00 1086 110 41 1 FALSE 0.99
colorectal cancer KRAS_G12V HLA-A 111 42 Tumor Type:overall -1.62 -6.08 3.60 1425.92 1.00 1086 110 41 1 FALSE 0.32
colorectal cancer KRAS_G12V EPHA7 67 23 Metastasis -0.32 -1.54 0.84 922.68 1.00 703 65 21 2 FALSE 0.23
colorectal cancer KRAS_G12V EPHA7 111 67 Primary -0.42 -1.43 0.44 923.82 1.00 1068 107 63 4 FALSE 0.43
non-small cell lung cancer KRAS_G12V EPHA7 44 54 Metastasis -0.46 -1.99 0.64 1459.95 1.00 1140 43 53 1 FALSE 0.33
non-small cell lung cancer KRAS_G12V EPHA7 113 75 Primary -0.27 -1.30 0.61 1411.18 1.00 1902 109 71 4 FALSE 0.22
colorectal cancer KRAS_G12V EPHA7 178 90 Tumor Type:overall -0.37 -1.74 0.86 1027.79 1.00 1771 172 84 6 FALSE 0.24
non-small cell lung cancer KRAS_G12V EPHA7 157 129 Tumor Type:overall -0.37 -1.69 0.80 1343.42 1.00 3042 152 124 5 FALSE 0.25
colorectal cancer KRAS_G12V NCOA3 67 14 Metastasis -0.70 -2.44 0.67 1328.64 1.00 712 66 13 1 TRUE 0.44
colorectal cancer KRAS_G12V NCOA3 111 42 Primary -0.74 -2.09 0.43 1224.25 1.00 1082 109 40 2 TRUE 0.60
colorectal cancer KRAS_G12V NCOA3 178 56 Tumor Type:overall -0.69 -2.38 0.74 1343.58 1.00 1794 175 53 3 TRUE 0.41
non-small cell lung cancer KRAS_G12V DROSHA 20 19 Metastasis -0.37 -3.72 1.35 918.16 1.00 636 20 19 0 FALSE 0.08
non-small cell lung cancer KRAS_G12V DROSHA 70 35 Primary 0.43 -0.78 1.47 1145.56 1.00 1103 66 31 4 FALSE 0.35
non-small cell lung cancer KRAS_G12V DROSHA 90 54 Tumor Type:overall 0.09 -2.05 1.55 1388.55 1.00 1739 86 50 4 FALSE 0.03
colorectal cancer KRAS_G12V SLX4 27 13 Metastasis -1.40 -4.08 0.34 1444.46 1.00 324 27 13 0 FALSE 0.62
colorectal cancer KRAS_G12V SLX4 69 41 Primary -1.10 -2.96 0.33 1470.84 1.00 667 67 39 2 FALSE 0.74
colorectal cancer KRAS_G12V SLX4 96 54 Tumor Type:overall -1.25 -3.60 0.34 1508.93 1.00 991 94 52 2 FALSE 0.65
colorectal cancer KRAS_G12V INPPL1 27 15 Metastasis -0.40 -2.00 0.88 1324.85 1.00 326 26 14 1 FALSE 0.24
colorectal cancer KRAS_G12V INPPL1 70 58 Primary -0.36 -1.40 0.61 1182.72 1.00 660 66 54 4 FALSE 0.32
colorectal cancer KRAS_G12V INPPL1 97 73 Tumor Type:overall -0.37 -1.83 0.91 1503.35 1.00 986 92 68 5 FALSE 0.22
colorectal cancer KRAS_G13D SPEN 66 45 Metastasis -0.44 -1.62 0.46 264.77 1.01 778 64 43 2 FALSE 0.39
colorectal cancer KRAS_G13D SPEN 107 110 Primary -0.32 -1.12 0.41 240.31 1.01 1163 100 103 7 FALSE 0.36
colorectal cancer KRAS_G13D SPEN 173 155 Tumor Type:overall -0.38 -1.53 0.55 502.58 1.00 1941 164 146 9 FALSE 0.29
colorectal cancer KRAS_G13D KMT2C 66 49 Metastasis -0.16 -1.15 0.74 1255.71 1.00 773 63 46 3 FALSE 0.13
colorectal cancer KRAS_G13D KMT2C 109 149 Primary 0.15 -0.45 0.70 1628.85 1.00 1146 95 135 14 FALSE 0.21
colorectal cancer KRAS_G13D KMT2C 175 198 Tumor Type:overall 0.01 -1.28 1.22 1412.72 1.00 1919 158 181 17 FALSE 0.00
colorectal cancer KRAS_G13D TP53 72 701 Metastasis -0.37 -0.78 0.06 1442.79 1.00 265 25 654 47 TRUE 1.13
colorectal cancer KRAS_G13D TP53 122 1018 Primary -0.52 -0.86 -0.21 1553.12 1.00 506 59 955 63 TRUE 2.67
colorectal cancer KRAS_G13D TP53 194 1719 Tumor Type:overall -0.43 -1.02 0.27 1574.80 1.00 771 84 1609 110 TRUE 0.57
colorectal cancer KRAS_G13D ATRX 67 33 Metastasis -0.14 -1.27 0.73 1358.98 1.00 784 65 31 2 TRUE 0.11
colorectal cancer KRAS_G13D ATRX 109 86 Primary 0.06 -0.66 0.76 874.14 1.00 1170 101 78 8 TRUE 0.06
colorectal cancer KRAS_G13D ATRX 176 119 Tumor Type:overall -0.03 -1.16 0.94 1229.95 1.00 1954 166 109 10 TRUE 0.02
colorectal cancer KRAS_G13D ATR 66 30 Metastasis 0.26 -0.70 1.08 1333.78 1.00 793 63 27 3 FALSE 0.24
colorectal cancer KRAS_G13D ATR 108 84 Primary 0.33 -0.36 0.98 1378.56 1.00 1180 99 75 9 FALSE 0.48
colorectal cancer KRAS_G13D ATR 174 114 Tumor Type:overall 0.28 -0.86 1.33 1466.42 1.00 1973 162 102 12 FALSE 0.22
colorectal cancer KRAS_G13D PDGFRA 69 15 Metastasis 0.60 -0.60 1.56 1426.88 1.01 872 67 13 2 TRUE 0.56
colorectal cancer KRAS_G13D PDGFRA 119 45 Primary 0.71 -0.16 1.50 1019.26 1.00 1344 112 38 7 TRUE 1.08
colorectal cancer KRAS_G13D PDGFRA 188 60 Tumor Type:overall 0.64 -0.64 1.75 1441.28 1.00 2216 179 51 9 TRUE 0.53
colorectal cancer KRAS_G13D FBXW7 72 90 Metastasis 0.94 0.37 1.50 1415.37 1.00 818 57 75 15 TRUE 2.95
colorectal cancer KRAS_G13D FBXW7 118 249 Primary 0.71 0.28 1.13 1453.89 1.00 1193 87 218 31 TRUE 3.06
colorectal cancer KRAS_G13D FBXW7 190 339 Tumor Type:overall 0.80 -0.12 1.76 1471.32 1.00 2011 144 293 46 TRUE 1.05
colorectal cancer KRAS_G13D MAP3K1 66 30 Metastasis 0.20 -0.72 1.03 1267.89 1.00 787 63 27 3 FALSE 0.19
colorectal cancer KRAS_G13D MAP3K1 106 62 Primary 0.20 -0.57 0.89 1122.13 1.00 1187 100 56 6 FALSE 0.23
colorectal cancer KRAS_G13D MAP3K1 172 92 Tumor Type:overall 0.20 -0.76 0.97 1050.13 1.00 1974 163 83 9 FALSE 0.18
colorectal cancer KRAS_G13D NSD1 66 23 Metastasis 0.17 -1.00 1.11 1002.59 1.01 793 64 21 2 FALSE 0.13
colorectal cancer KRAS_G13D NSD1 107 63 Primary 0.31 -0.53 1.01 793.82 1.00 1189 100 56 7 FALSE 0.36
colorectal cancer KRAS_G13D NSD1 173 86 Tumor Type:overall 0.25 -0.92 1.32 1178.40 1.00 1982 164 77 9 FALSE 0.18
colorectal cancer KRAS_G13D FLT4 66 41 Metastasis -0.58 -2.18 0.40 1079.30 1.00 774 65 40 1 TRUE 0.43
colorectal cancer KRAS_G13D FLT4 105 98 Primary -0.15 -0.93 0.57 1405.90 1.00 1161 97 90 8 TRUE 0.15
colorectal cancer KRAS_G13D FLT4 171 139 Tumor Type:overall -0.37 -1.74 0.67 1266.37 1.00 1935 162 130 9 TRUE 0.26
colorectal cancer KRAS_G13D PTPRD 66 28 Metastasis -0.34 -1.58 0.64 1170.34 1.00 789 65 27 1 FALSE 0.26
colorectal cancer KRAS_G13D PTPRD 106 75 Primary -0.05 -0.72 0.76 39.53 1.06 1183 99 68 7 FALSE 0.04
colorectal cancer KRAS_G13D PTPRD 172 103 Tumor Type:overall -0.22 -1.38 0.90 430.83 1.01 1972 164 95 8 FALSE 0.14
colorectal cancer KRAS_G13D RET 70 20 Metastasis 0.44 -0.64 1.27 354.93 1.02 866 68 18 2 TRUE 0.42
colorectal cancer KRAS_G13D RET 116 45 Primary 0.52 -0.34 1.28 294.31 1.01 1344 110 39 6 TRUE 0.66
colorectal cancer KRAS_G13D RET 186 65 Tumor Type:overall 0.48 -0.61 1.34 417.82 1.01 2210 178 57 8 TRUE 0.45
colorectal cancer KRAS_G13D KDM5A 66 24 Metastasis -0.14 -1.64 0.95 1420.11 1.00 798 65 23 1 FALSE 0.08
colorectal cancer KRAS_G13D KDM5A 106 72 Primary 0.40 -0.36 1.09 1538.71 1.00 1180 97 63 9 FALSE 0.55
colorectal cancer KRAS_G13D KDM5A 172 96 Tumor Type:overall 0.15 -1.25 1.51 1560.16 1.00 1978 162 86 10 FALSE 0.08
colorectal cancer KRAS_G13D PIK3C2G 66 20 Metastasis -0.41 -1.93 0.78 1305.32 1.00 796 65 19 1 FALSE 0.26
colorectal cancer KRAS_G13D PIK3C2G 107 67 Primary -0.22 -1.22 0.61 1285.72 1.00 1183 102 62 5 FALSE 0.19
colorectal cancer KRAS_G13D PIK3C2G 173 87 Tumor Type:overall -0.33 -1.84 1.03 1504.42 1.00 1979 167 81 6 FALSE 0.19
colorectal cancer KRAS_G13D CREBBP 66 37 Metastasis 0.47 -0.48 1.34 1428.74 1.00 788 61 32 5 TRUE 0.49
colorectal cancer KRAS_G13D CREBBP 108 151 Primary 0.14 -0.47 0.70 1524.36 1.00 1132 95 138 13 TRUE 0.20
colorectal cancer KRAS_G13D CREBBP 174 188 Tumor Type:overall 0.30 -1.07 1.62 1676.73 1.00 1920 156 170 18 TRUE 0.18
colorectal cancer KRAS_G13D AXIN2 66 26 Metastasis 0.00 -1.00 0.98 141.03 1.04 790 64 24 2 TRUE 0.00
colorectal cancer KRAS_G13D AXIN2 106 89 Primary 0.14 -0.39 0.87 5.59 1.22 1170 97 80 9 TRUE 0.16
colorectal cancer KRAS_G13D AXIN2 172 115 Tumor Type:overall 0.06 -1.10 1.41 516.07 1.02 1960 161 104 11 TRUE 0.03
colorectal cancer KRAS_G13D DOT1L 66 23 Metastasis 0.06 -1.36 1.03 358.05 1.01 794 65 22 1 FALSE 0.03
colorectal cancer KRAS_G13D DOT1L 105 61 Primary 0.44 -0.38 1.13 869.64 1.00 1191 97 53 8 FALSE 0.61
colorectal cancer KRAS_G13D DOT1L 171 84 Tumor Type:overall 0.26 -1.07 1.36 513.57 1.01 1985 162 75 9 FALSE 0.18
colorectal cancer KRAS_G13D PTPRS 66 63 Metastasis 0.23 -0.53 0.95 1382.13 1.00 764 60 57 6 FALSE 0.26
colorectal cancer KRAS_G13D PTPRS 108 191 Primary 0.30 -0.20 0.78 1534.17 1.00 1101 89 172 19 FALSE 0.64
colorectal cancer KRAS_G13D PTPRS 174 254 Tumor Type:overall 0.26 -0.83 1.36 1525.27 1.00 1865 149 229 25 FALSE 0.19
colorectal cancer KRAS_G13D SMARCA4 66 40 Metastasis 0.29 -0.61 1.21 1323.65 1.00 783 61 35 5 FALSE 0.27
colorectal cancer KRAS_G13D SMARCA4 107 129 Primary -0.07 -0.78 0.55 1645.73 1.00 1145 98 120 9 FALSE 0.08
colorectal cancer KRAS_G13D SMARCA4 173 169 Tumor Type:overall 0.14 -1.05 1.59 1347.85 1.00 1928 159 155 14 FALSE 0.08
colorectal cancer KRAS_G13D PTPRT 66 58 Metastasis 0.24 -0.78 0.89 1441.06 1.00 762 62 54 4 FALSE 0.25
colorectal cancer KRAS_G13D PTPRT 109 127 Primary 0.59 0.08 1.09 1040.53 1.00 1139 91 109 18 FALSE 1.63
colorectal cancer KRAS_G13D PTPRT 175 185 Tumor Type:overall 0.41 -0.64 1.26 1549.37 1.00 1901 153 163 22 FALSE 0.40
colorectal cancer KRAS_G13D HGF 66 22 Metastasis 0.21 -0.99 1.12 103.78 1.03 791 65 21 1 FALSE 0.15
colorectal cancer KRAS_G13D HGF 105 34 Primary 0.36 -0.63 1.19 107.70 1.04 1211 100 29 5 FALSE 0.34
colorectal cancer KRAS_G13D HGF 171 56 Tumor Type:overall 0.28 -0.76 1.22 171.07 1.03 2002 165 50 6 FALSE 0.21
colorectal cancer KRAS_G13D BLM 66 14 Metastasis -0.04 -1.74 1.21 1422.23 1.00 803 65 13 1 TRUE 0.02
colorectal cancer KRAS_G13D BLM 105 56 Primary 0.26 -0.67 1.06 1430.99 1.00 1190 99 50 6 TRUE 0.26
colorectal cancer KRAS_G13D BLM 171 70 Tumor Type:overall 0.10 -1.60 1.51 1144.29 1.00 1993 164 63 7 TRUE 0.05
colorectal cancer KRAS_G13D PIK3CA 72 151 Metastasis 0.66 0.15 1.13 1458.00 1.00 757 55 134 17 TRUE 2.08
colorectal cancer KRAS_G13D PIK3CA 123 360 Primary 1.00 0.65 1.36 1441.33 1.00 1115 69 306 54 TRUE 7.52
colorectal cancer KRAS_G13D PIK3CA 195 511 Tumor Type:overall 0.84 0.01 1.69 1466.08 1.00 1872 124 440 71 TRUE 1.28
colorectal cancer KRAS_G13D ESR1 66 22 Metastasis 0.17 -1.35 1.15 812.22 1.00 791 65 21 1 TRUE 0.11
colorectal cancer KRAS_G13D ESR1 106 50 Primary 0.57 -0.29 1.32 831.69 1.00 1196 98 42 8 TRUE 0.78
colorectal cancer KRAS_G13D ESR1 172 72 Tumor Type:overall 0.36 -1.06 1.43 939.42 1.00 1987 163 63 9 TRUE 0.25
colorectal cancer KRAS_G13D ALK 69 37 Metastasis 0.91 0.32 1.64 83.39 1.03 855 62 30 7 TRUE 1.93
colorectal cancer KRAS_G13D ALK 119 78 Primary 0.84 0.32 1.35 76.82 1.02 1327 107 66 12 TRUE 2.34
colorectal cancer KRAS_G13D ALK 188 115 Tumor Type:overall 0.87 0.16 1.65 151.87 1.02 2182 169 96 19 TRUE 1.51
colorectal cancer KRAS_G13D RNF43 68 64 Metastasis 0.14 -0.61 0.85 1613.89 1.00 766 62 58 6 TRUE 0.15
colorectal cancer KRAS_G13D RNF43 109 203 Primary 0.09 -0.48 0.57 1375.73 1.00 1100 92 186 17 TRUE 0.13
colorectal cancer KRAS_G13D RNF43 177 267 Tumor Type:overall 0.11 -1.12 1.25 1520.03 1.00 1866 154 244 23 TRUE 0.07
colorectal cancer KRAS_G13D LATS1 66 15 Metastasis -0.73 -3.65 0.74 999.26 1.00 798 66 15 0 FALSE 0.26
colorectal cancer KRAS_G13D LATS1 105 40 Primary -0.11 -1.29 0.92 804.83 1.00 1205 101 36 4 FALSE 0.07
colorectal cancer KRAS_G13D LATS1 171 55 Tumor Type:overall -0.40 -2.48 1.07 1266.12 1.00 2003 167 51 4 FALSE 0.17
colorectal cancer KRAS_G13D LATS2 66 27 Metastasis -0.11 -1.25 0.87 729.70 1.00 788 63 24 3 FALSE 0.08
colorectal cancer KRAS_G13D LATS2 105 43 Primary -0.25 -1.44 0.66 725.02 1.00 1198 103 41 2 FALSE 0.19
colorectal cancer KRAS_G13D LATS2 171 70 Tumor Type:overall -0.18 -1.43 0.87 891.06 1.00 1986 166 65 5 FALSE 0.12
colorectal cancer KRAS_G13D PTEN 70 43 Metastasis 1.08 0.31 1.83 1210.17 1.00 855 61 34 9 TRUE 2.18
colorectal cancer KRAS_G13D PTEN 120 142 Primary 0.46 -0.12 0.98 1358.11 1.01 1290 105 127 15 TRUE 0.97
colorectal cancer KRAS_G13D PTEN 190 185 Tumor Type:overall 0.75 -0.66 2.09 1424.95 1.00 2145 166 161 24 TRUE 0.55
colorectal cancer KRAS_G13D BCOR 66 18 Metastasis -0.29 -2.15 1.00 1351.57 1.00 796 65 17 1 FALSE 0.14
colorectal cancer KRAS_G13D BCOR 107 94 Primary 0.16 -0.60 0.86 1470.12 1.00 1165 98 85 9 FALSE 0.17
colorectal cancer KRAS_G13D BCOR 173 112 Tumor Type:overall -0.10 -2.02 1.54 1399.86 1.00 1961 163 102 10 FALSE 0.04
colorectal cancer KRAS_G13D CTNNB1 69 44 Metastasis 0.19 -0.91 0.98 1579.37 1.00 844 66 41 3 TRUE 0.17
colorectal cancer KRAS_G13D CTNNB1 116 119 Primary 0.58 0.01 1.12 1214.83 1.00 1285 100 103 16 TRUE 1.39
colorectal cancer KRAS_G13D CTNNB1 185 163 Tumor Type:overall 0.40 -0.81 1.34 1617.11 1.00 2129 166 144 19 TRUE 0.32
colorectal cancer KRAS_G13D ARID1A 67 73 Metastasis 0.08 -0.68 0.79 1602.92 1.00 766 61 67 6 TRUE 0.09
colorectal cancer KRAS_G13D ARID1A 112 242 Primary 0.16 -0.30 0.61 1514.72 1.00 1082 90 220 22 TRUE 0.31
colorectal cancer KRAS_G13D ARID1A 179 315 Tumor Type:overall 0.13 -1.02 1.31 1506.46 1.00 1848 151 287 28 TRUE 0.09
colorectal cancer KRAS_G13D PIK3R1 66 27 Metastasis 0.22 -0.86 1.23 1477.84 1.00 793 63 24 3 TRUE 0.17
colorectal cancer KRAS_G13D PIK3R1 106 89 Primary 0.16 -0.60 0.82 1453.54 1.00 1167 98 81 8 TRUE 0.18
colorectal cancer KRAS_G13D PIK3R1 172 116 Tumor Type:overall 0.21 -1.15 1.40 1493.35 1.00 1960 161 105 11 TRUE 0.12
colorectal cancer KRAS_G13D IKZF1 66 24 Metastasis 0.01 -1.72 1.05 1304.36 1.00 791 65 23 1 TRUE 0.00
colorectal cancer KRAS_G13D IKZF1 105 62 Primary 0.54 -0.21 1.27 1357.00 1.00 1186 96 53 9 TRUE 0.80
colorectal cancer KRAS_G13D IKZF1 171 86 Tumor Type:overall 0.24 -1.24 1.33 1382.16 1.00 1977 161 76 10 TRUE 0.14
colorectal cancer KRAS_G13D TERT 66 27 Metastasis 0.20 -0.87 1.11 1309.51 1.00 792 63 24 3 TRUE 0.17
colorectal cancer KRAS_G13D TERT 105 71 Primary 0.13 -0.70 0.84 1488.75 1.00 1178 99 65 6 TRUE 0.12
colorectal cancer KRAS_G13D TERT 171 98 Tumor Type:overall 0.16 -0.99 1.12 1463.81 1.00 1970 162 89 9 TRUE 0.12
colorectal cancer KRAS_G13D FAT1 67 62 Metastasis 0.26 -0.58 0.96 1432.71 1.00 775 62 57 5 FALSE 0.30
colorectal cancer KRAS_G13D FAT1 117 165 Primary 0.70 0.26 1.17 291.50 1.01 1139 92 140 25 FALSE 2.46
colorectal cancer KRAS_G13D FAT1 184 227 Tumor Type:overall 0.50 -0.55 1.49 1565.77 1.00 1914 154 197 30 FALSE 0.49
colorectal cancer KRAS_G13D FGFR4 105 46 Primary 0.73 -0.16 1.55 1322.65 1.00 1202 98 39 7 TRUE 1.02
colorectal cancer KRAS_G13D FGFR4 105 46 Tumor Type:overall 0.64 -3.69 4.69 1487.75 1.00 1202 98 39 7 TRUE 0.13
colorectal cancer KRAS_G13D CIC 67 37 Metastasis -0.08 -1.10 0.93 539.53 1.01 784 63 33 4 TRUE 0.05
colorectal cancer KRAS_G13D CIC 105 100 Primary -0.56 -1.59 0.25 1029.58 1.00 1163 101 96 4 TRUE 0.63
colorectal cancer KRAS_G13D CIC 172 137 Tumor Type:overall -0.32 -1.62 0.94 783.39 1.01 1947 164 129 8 TRUE 0.21
colorectal cancer KRAS_G13D KDM6A 66 13 Metastasis -1.22 -4.43 0.50 914.04 1.00 800 66 13 0 FALSE 0.45
colorectal cancer KRAS_G13D KDM6A 105 49 Primary -0.60 -1.98 0.47 1050.57 1.00 1193 102 46 3 FALSE 0.47
colorectal cancer KRAS_G13D KDM6A 171 62 Tumor Type:overall -0.85 -3.06 0.89 1317.32 1.00 1993 168 59 3 FALSE 0.39
colorectal cancer KRAS_G13D NCOR1 67 37 Metastasis 0.43 -0.42 1.26 1382.41 1.00 783 62 32 5 FALSE 0.52
colorectal cancer KRAS_G13D NCOR1 106 98 Primary 0.24 -0.45 0.85 1513.08 1.00 1168 97 89 9 FALSE 0.32
colorectal cancer KRAS_G13D NCOR1 173 135 Tumor Type:overall 0.33 -0.66 1.30 1050.77 1.00 1951 159 121 14 FALSE 0.28
colorectal cancer KRAS_G13D POLE 67 28 Metastasis 0.28 -0.81 1.21 1578.45 1.00 787 64 25 3 TRUE 0.24
colorectal cancer KRAS_G13D POLE 108 113 Primary 0.44 -0.17 1.01 1419.81 1.00 1160 95 100 13 TRUE 0.86
colorectal cancer KRAS_G13D POLE 175 141 Tumor Type:overall 0.35 -0.99 1.70 1401.58 1.00 1947 159 125 16 TRUE 0.22
colorectal cancer KRAS_G13D ABL1 69 17 Metastasis -0.04 -1.71 1.09 349.33 1.01 870 68 16 1 TRUE 0.02
colorectal cancer KRAS_G13D ABL1 118 56 Primary 0.24 -0.74 1.04 231.66 1.02 1336 112 50 6 TRUE 0.22
colorectal cancer KRAS_G13D ABL1 187 73 Tumor Type:overall 0.08 -1.62 1.35 720.48 1.01 2206 180 66 7 TRUE 0.04
colorectal cancer KRAS_G13D FOXP1 66 15 Metastasis 0.08 -1.70 1.25 1499.92 1.00 798 65 14 1 FALSE 0.04
colorectal cancer KRAS_G13D FOXP1 106 55 Primary 0.44 -0.45 1.23 1332.72 1.00 1192 99 48 7 FALSE 0.54
colorectal cancer KRAS_G13D FOXP1 172 70 Tumor Type:overall 0.28 -1.24 1.59 1532.30 1.00 1990 164 62 8 FALSE 0.15
colorectal cancer KRAS_G13D NOTCH2 66 18 Metastasis 0.03 -1.52 1.11 792.30 1.00 797 65 17 1 TRUE 0.02
colorectal cancer KRAS_G13D NOTCH2 105 55 Primary 0.40 -0.46 1.17 1346.51 1.00 1195 98 48 7 TRUE 0.48
colorectal cancer KRAS_G13D NOTCH2 171 73 Tumor Type:overall 0.21 -1.25 1.43 1352.95 1.00 1992 163 65 8 TRUE 0.12
colorectal cancer KRAS_G13D TGFBR2 66 26 Metastasis 0.40 -0.61 1.28 1500.82 1.00 789 63 23 3 TRUE 0.39
colorectal cancer KRAS_G13D TGFBR2 105 88 Primary 0.52 -0.18 1.12 1274.19 1.00 1165 94 77 11 TRUE 0.93
colorectal cancer KRAS_G13D TGFBR2 171 114 Tumor Type:overall 0.44 -0.78 1.54 1519.45 1.00 1954 157 100 14 TRUE 0.34
colorectal cancer KRAS_G13D SMO 69 19 Metastasis -0.07 -1.27 1.03 1451.60 1.00 867 67 17 2 TRUE 0.04
colorectal cancer KRAS_G13D SMO 117 52 Primary -0.25 -1.34 0.64 1114.89 1.00 1338 114 49 3 TRUE 0.20
colorectal cancer KRAS_G13D SMO 186 71 Tumor Type:overall -0.16 -1.46 1.08 1509.39 1.00 2205 181 66 5 TRUE 0.09
colorectal cancer KRAS_G13D RPS6KA4 106 53 Primary 0.70 -0.18 1.45 965.18 1.00 1193 98 45 8 FALSE 1.06
colorectal cancer KRAS_G13D RPS6KA4 106 53 Tumor Type:overall 0.56 -3.83 4.43 1537.50 1.00 1193 98 45 8 FALSE 0.11
colorectal cancer KRAS_G13D KMT2A 66 37 Metastasis -1.82 -6.67 0.28 1288.27 1.00 782 66 37 0 FALSE 0.49
colorectal cancer KRAS_G13D KMT2A 110 111 Primary 0.52 -0.11 1.10 419.23 1.00 1162 95 96 15 FALSE 0.96
colorectal cancer KRAS_G13D KMT2A 176 148 Tumor Type:overall -0.60 -3.83 1.59 1565.16 1.00 1944 161 133 15 FALSE 0.19
colorectal cancer KRAS_G13D JAK3 69 22 Metastasis -0.67 -2.08 0.53 883.79 1.00 865 68 21 1 TRUE 0.51
colorectal cancer KRAS_G13D JAK3 116 41 Primary -0.65 -1.98 0.50 907.51 1.00 1345 114 39 2 TRUE 0.54
colorectal cancer KRAS_G13D JAK3 185 63 Tumor Type:overall -0.67 -2.11 0.53 1005.56 1.00 2210 182 60 3 TRUE 0.51
colorectal cancer KRAS_G13D BRCA2 67 48 Metastasis -0.02 -1.01 0.77 1621.50 1.00 776 64 45 3 TRUE 0.02
colorectal cancer KRAS_G13D BRCA2 113 142 Primary 0.39 -0.14 0.91 1547.81 1.00 1156 96 125 17 TRUE 0.83
colorectal cancer KRAS_G13D BRCA2 180 190 Tumor Type:overall 0.20 -0.90 1.32 1587.77 1.00 1932 160 170 20 TRUE 0.14
colorectal cancer KRAS_G13D NOTCH3 66 58 Metastasis 0.19 -0.59 0.86 1347.92 1.00 769 61 53 5 TRUE 0.21
colorectal cancer KRAS_G13D NOTCH3 106 142 Primary 0.32 -0.21 0.83 1309.17 1.00 1140 91 127 15 TRUE 0.63
colorectal cancer KRAS_G13D NOTCH3 172 200 Tumor Type:overall 0.24 -0.72 1.11 1472.48 1.00 1909 152 180 20 TRUE 0.23
colorectal cancer KRAS_G13D NOTCH4 66 33 Metastasis 0.25 -0.72 1.21 1433.39 1.00 784 62 29 4 TRUE 0.22
colorectal cancer KRAS_G13D NOTCH4 108 89 Primary 0.04 -0.70 0.74 1387.79 1.00 1165 101 82 7 TRUE 0.04
colorectal cancer KRAS_G13D NOTCH4 174 122 Tumor Type:overall 0.15 -0.92 1.28 1333.23 1.00 1949 163 111 11 TRUE 0.10
colorectal cancer KRAS_G13D FGFR3 69 14 Metastasis -0.56 -2.24 0.90 1487.81 1.00 872 68 13 1 TRUE 0.32
colorectal cancer KRAS_G13D FGFR3 116 46 Primary -0.68 -2.20 0.46 1335.95 1.00 1341 114 44 2 TRUE 0.50
colorectal cancer KRAS_G13D FGFR3 185 60 Tumor Type:overall -0.64 -2.48 0.83 1359.60 1.00 2213 182 57 3 TRUE 0.35
colorectal cancer KRAS_G13D IGF1R 66 22 Metastasis -0.42 -1.92 0.65 911.28 1.00 795 65 21 1 TRUE 0.27
colorectal cancer KRAS_G13D IGF1R 105 58 Primary -0.29 -1.38 0.58 535.84 1.01 1188 101 54 4 TRUE 0.24
colorectal cancer KRAS_G13D IGF1R 171 80 Tumor Type:overall -0.35 -1.72 0.71 789.79 1.00 1983 166 75 5 TRUE 0.23
colorectal cancer KRAS_G13D KDM5C 66 14 Metastasis -0.15 -1.86 1.11 1469.08 1.00 800 65 13 1 FALSE 0.08
colorectal cancer KRAS_G13D KDM5C 106 55 Primary 0.05 -0.94 0.85 1439.80 1.00 1196 101 50 5 FALSE 0.04
colorectal cancer KRAS_G13D KDM5C 172 69 Tumor Type:overall -0.05 -1.70 1.38 1671.06 1.00 1996 166 63 6 FALSE 0.02
colorectal cancer KRAS_G13D EPHB1 66 25 Metastasis -1.34 -3.52 -0.03 1420.82 1.00 787 66 25 0 FALSE 0.64
colorectal cancer KRAS_G13D EPHB1 105 57 Primary -1.02 -2.22 0.15 24.38 1.06 1185 102 54 3 FALSE 1.12
colorectal cancer KRAS_G13D EPHB1 171 82 Tumor Type:overall -1.16 -2.83 0.24 747.94 1.01 1972 168 79 3 FALSE 0.96
colorectal cancer KRAS_G13D IRS2 66 11 Metastasis -1.26 -5.61 0.86 1315.47 1.00 802 66 11 0 FALSE 0.33
colorectal cancer KRAS_G13D IRS2 105 76 Primary 0.21 -0.65 0.97 1352.60 1.00 1176 97 68 8 FALSE 0.22
colorectal cancer KRAS_G13D IRS2 171 87 Tumor Type:overall -0.53 -3.92 1.90 1426.98 1.00 1978 163 79 8 FALSE 0.15
colorectal cancer KRAS_G13D FANCA 66 12 Metastasis -0.81 -5.41 1.22 977.83 1.00 802 66 12 0 TRUE 0.17
colorectal cancer KRAS_G13D FANCA 105 53 Primary 1.06 0.30 1.78 1178.45 1.00 1198 94 42 11 TRUE 2.35
colorectal cancer KRAS_G13D FANCA 171 65 Tumor Type:overall 0.15 -2.96 2.24 1382.48 1.00 2000 160 54 11 TRUE 0.04
colorectal cancer KRAS_G13D PIK3CB 66 12 Metastasis -1.15 -5.27 0.75 1205.98 1.00 803 66 12 0 FALSE 0.33
colorectal cancer KRAS_G13D PIK3CB 107 56 Primary -0.09 -1.13 0.84 1178.59 1.00 1195 102 51 5 FALSE 0.06
colorectal cancer KRAS_G13D PIK3CB 173 68 Tumor Type:overall -0.56 -3.19 1.44 1510.93 1.00 1998 168 63 5 FALSE 0.20
colorectal cancer KRAS_G13D ERBB3 66 39 Metastasis 0.47 -0.14 1.17 40.32 1.09 781 61 34 5 TRUE 0.77
colorectal cancer KRAS_G13D ERBB3 107 83 Primary 0.46 -0.09 1.06 46.16 1.08 1172 97 73 10 TRUE 0.86
colorectal cancer KRAS_G13D ERBB3 173 122 Tumor Type:overall 0.44 -0.30 1.18 92.64 1.05 1953 158 107 15 TRUE 0.59
colorectal cancer KRAS_G13D SMAD4 70 149 Metastasis -0.21 -0.77 0.32 956.72 1.00 754 59 138 11 TRUE 0.34
colorectal cancer KRAS_G13D SMAD4 117 211 Primary -0.32 -0.88 0.16 562.22 1.01 1204 106 200 11 TRUE 0.63
colorectal cancer KRAS_G13D SMAD4 187 360 Tumor Type:overall -0.27 -0.91 0.31 1227.24 1.00 1958 165 338 22 TRUE 0.33
colorectal cancer KRAS_G13D ATM 69 71 Metastasis -0.49 -1.87 0.51 1418.93 1.00 829 67 69 2 TRUE 0.36
colorectal cancer KRAS_G13D ATM 123 160 Primary 0.55 0.02 1.03 1157.87 1.00 1277 101 138 22 TRUE 1.45
colorectal cancer KRAS_G13D ATM 192 231 Tumor Type:overall 0.03 -1.55 1.34 1432.81 1.00 2106 168 207 24 TRUE 0.02
colorectal cancer KRAS_G13D RB1 118 58 Primary -0.26 -1.43 0.75 1105.73 1.00 1339 114 54 4 TRUE 0.19
colorectal cancer KRAS_G13D RB1 118 58 Tumor Type:overall -0.24 -4.69 3.72 1439.70 1.00 1339 114 54 4 TRUE 0.04
colorectal cancer KRAS_G13D KMT2D 69 82 Metastasis 0.08 -0.69 0.77 1431.69 1.00 759 62 75 7 FALSE 0.08
colorectal cancer KRAS_G13D KMT2D 113 306 Primary 0.13 -0.36 0.57 1323.33 1.00 1075 87 280 26 FALSE 0.24
colorectal cancer KRAS_G13D KMT2D 182 388 Tumor Type:overall 0.11 -1.17 1.30 1395.38 1.00 1834 149 355 33 FALSE 0.07
colorectal cancer KRAS_G13D TSC2 67 25 Metastasis 0.15 -0.96 1.22 1417.80 1.00 793 64 22 3 TRUE 0.11
colorectal cancer KRAS_G13D TSC2 105 90 Primary -0.12 -0.98 0.64 1560.86 1.00 1168 99 84 6 TRUE 0.12
colorectal cancer KRAS_G13D TSC2 172 115 Tumor Type:overall -0.01 -1.48 1.38 1469.41 1.00 1961 163 106 9 TRUE 0.01
colorectal cancer KRAS_G13D APC 107 1010 Metastasis 0.45 0.05 0.86 1402.23 1.00 269 17 920 90 TRUE 1.60
colorectal cancer KRAS_G13D APC 173 1528 Primary 0.45 0.11 0.78 1326.17 1.00 507 33 1388 140 TRUE 2.09
colorectal cancer KRAS_G13D APC 280 2538 Tumor Type:overall 0.44 -0.08 0.96 1365.52 1.00 776 50 2308 230 TRUE 0.88
colorectal cancer KRAS_G13D ERBB2 70 32 Metastasis 1.32 0.42 2.20 843.27 1.01 865 61 23 9 TRUE 2.32
colorectal cancer KRAS_G13D ERBB2 116 72 Primary 0.33 -0.59 1.07 1188.64 1.00 1319 110 66 6 TRUE 0.35
colorectal cancer KRAS_G13D ERBB2 186 104 Tumor Type:overall 0.82 -0.62 2.30 1481.58 1.00 2184 171 89 15 TRUE 0.56
colorectal cancer KRAS_G13D JAK1 66 12 Metastasis 0.37 -1.39 1.65 1405.14 1.00 801 65 11 1 TRUE 0.19
colorectal cancer KRAS_G13D JAK1 110 63 Primary 1.10 0.44 1.74 1352.78 1.00 1195 97 50 13 TRUE 3.08
colorectal cancer KRAS_G13D JAK1 176 75 Tumor Type:overall 0.70 -1.22 2.27 1548.80 1.00 1996 162 61 14 TRUE 0.36
colorectal cancer KRAS_G13D ARID2 67 31 Metastasis 0.03 -0.94 0.91 1504.54 1.00 788 64 28 3 FALSE 0.02
colorectal cancer KRAS_G13D ARID2 105 79 Primary -0.03 -0.86 0.66 1397.36 1.00 1172 99 73 6 FALSE 0.03
colorectal cancer KRAS_G13D ARID2 172 110 Tumor Type:overall 0.00 -1.03 0.99 1406.09 1.00 1960 163 101 9 FALSE 0.00
colorectal cancer KRAS_G13D SOX17 66 30 Metastasis 0.05 -0.81 0.89 1007.38 1.00 788 63 27 3 FALSE 0.04
colorectal cancer KRAS_G13D SOX17 105 68 Primary -0.02 -0.88 0.77 1228.36 1.00 1177 100 63 5 FALSE 0.02
colorectal cancer KRAS_G13D SOX17 171 98 Tumor Type:overall 0.01 -1.00 0.93 1199.00 1.00 1965 163 90 8 FALSE 0.00
colorectal cancer KRAS_G13D MTOR 66 41 Metastasis 0.38 -0.49 1.07 1525.83 1.00 779 62 37 4 TRUE 0.47
colorectal cancer KRAS_G13D MTOR 109 99 Primary 0.53 -0.06 1.09 1431.86 1.00 1163 96 86 13 TRUE 1.12
colorectal cancer KRAS_G13D MTOR 175 140 Tumor Type:overall 0.46 -0.48 1.30 1640.52 1.00 1942 158 123 17 TRUE 0.51
colorectal cancer KRAS_G13D IRS1 66 19 Metastasis 0.36 -0.94 1.44 1621.70 1.00 796 64 17 2 FALSE 0.27
colorectal cancer KRAS_G13D IRS1 108 78 Primary 0.62 0.00 1.23 1559.05 1.00 1176 97 67 11 FALSE 1.29
colorectal cancer KRAS_G13D IRS1 174 97 Tumor Type:overall 0.48 -0.95 1.86 1512.31 1.00 1972 161 84 13 FALSE 0.31
colorectal cancer KRAS_G13D NOTCH1 71 39 Metastasis 0.30 -0.61 1.13 1590.59 1.00 853 67 35 4 TRUE 0.30
colorectal cancer KRAS_G13D NOTCH1 121 133 Primary 0.34 -0.26 0.89 1452.07 1.00 1293 107 119 14 TRUE 0.62
colorectal cancer KRAS_G13D NOTCH1 192 172 Tumor Type:overall 0.31 -0.75 1.37 1552.70 1.00 2146 174 154 18 TRUE 0.23
colorectal cancer KRAS_G13D NTRK1 66 16 Metastasis 0.62 -0.48 1.69 1368.14 1.00 799 63 13 3 TRUE 0.57
colorectal cancer KRAS_G13D NTRK1 106 48 Primary 0.39 -0.61 1.18 1425.44 1.00 1195 101 43 5 TRUE 0.41
colorectal cancer KRAS_G13D NTRK1 172 64 Tumor Type:overall 0.47 -0.90 1.63 1507.08 1.00 1994 164 56 8 TRUE 0.32
colorectal cancer KRAS_G13D CASP8 66 17 Metastasis 0.89 -0.29 1.90 1458.84 1.00 800 63 14 3 FALSE 0.96
colorectal cancer KRAS_G13D CASP8 111 79 Primary 1.11 0.53 1.67 1428.46 1.00 1179 95 63 16 FALSE 3.86
colorectal cancer KRAS_G13D CASP8 177 96 Tumor Type:overall 0.98 -0.52 2.34 1420.84 1.00 1979 158 77 19 FALSE 0.71
colorectal cancer KRAS_G13D SETD2 66 29 Metastasis 0.62 -0.27 1.48 1337.18 1.00 792 62 25 4 FALSE 0.83
colorectal cancer KRAS_G13D SETD2 110 84 Primary 0.68 0.05 1.27 1190.36 1.00 1175 98 72 12 FALSE 1.50
colorectal cancer KRAS_G13D SETD2 176 113 Tumor Type:overall 0.65 -0.32 1.62 1349.46 1.00 1967 160 97 16 FALSE 0.70
colorectal cancer KRAS_G13D PBRM1 66 15 Metastasis -1.23 -5.47 0.77 1339.48 1.00 799 66 15 0 TRUE 0.35
colorectal cancer KRAS_G13D PBRM1 108 79 Primary 0.31 -0.47 1.00 1634.68 1.00 1174 99 70 9 TRUE 0.40
colorectal cancer KRAS_G13D PBRM1 174 94 Tumor Type:overall -0.40 -3.42 1.65 1377.66 1.00 1973 165 85 9 TRUE 0.13
colorectal cancer KRAS_G13D EPHA3 66 34 Metastasis 0.55 -0.28 1.26 1203.20 1.00 784 61 29 5 FALSE 0.79
colorectal cancer KRAS_G13D EPHA3 107 79 Primary 0.46 -0.22 1.08 1115.92 1.00 1174 98 70 9 FALSE 0.82
colorectal cancer KRAS_G13D EPHA3 173 113 Tumor Type:overall 0.49 -0.51 1.34 1305.91 1.00 1958 159 99 14 FALSE 0.53
colorectal cancer KRAS_G13D KIT 69 17 Metastasis -2.15 -5.06 -0.13 199.81 1.02 868 69 17 0 TRUE 0.96
colorectal cancer KRAS_G13D KIT 116 37 Primary -2.02 -4.44 -0.12 141.31 1.02 1349 115 36 1 TRUE 1.02
colorectal cancer KRAS_G13D KIT 185 54 Tumor Type:overall -2.08 -4.66 -0.03 171.24 1.02 2217 184 53 1 TRUE 0.99
colorectal cancer KRAS_G13D KDR 70 15 Metastasis 0.56 -0.62 1.66 1474.94 1.00 871 68 13 2 TRUE 0.48
colorectal cancer KRAS_G13D KDR 120 60 Primary 0.71 0.02 1.38 1272.90 1.00 1337 111 51 9 TRUE 1.35
colorectal cancer KRAS_G13D KDR 190 75 Tumor Type:overall 0.63 -0.76 2.00 1176.70 1.00 2208 179 64 11 TRUE 0.43
colorectal cancer KRAS_G13D RICTOR 66 11 Metastasis 0.31 -1.51 1.63 1471.45 1.00 804 65 10 1 FALSE 0.16
colorectal cancer KRAS_G13D RICTOR 107 59 Primary 0.86 0.13 1.54 1757.26 1.00 1194 97 49 10 FALSE 1.75
colorectal cancer KRAS_G13D RICTOR 173 70 Tumor Type:overall 0.59 -1.34 2.33 1563.14 1.00 1998 162 59 11 FALSE 0.29
colorectal cancer KRAS_G13D RAD50 67 18 Metastasis 0.58 -0.53 1.44 604.36 1.01 798 65 16 2 FALSE 0.63
colorectal cancer KRAS_G13D RAD50 107 42 Primary 0.71 -0.12 1.45 302.06 1.00 1203 100 35 7 FALSE 1.10
colorectal cancer KRAS_G13D RAD50 174 60 Tumor Type:overall 0.65 -0.48 1.54 598.36 1.00 2001 165 51 9 FALSE 0.68
colorectal cancer KRAS_G13D CSF1R 69 18 Metastasis -0.04 -1.43 0.98 1201.03 1.00 872 68 17 1 TRUE 0.02
colorectal cancer KRAS_G13D CSF1R 116 38 Primary 0.09 -0.98 0.95 1107.10 1.00 1350 112 34 4 TRUE 0.07
colorectal cancer KRAS_G13D CSF1R 185 56 Tumor Type:overall 0.00 -1.28 1.02 1177.81 1.00 2222 180 51 5 TRUE 0.00
colorectal cancer KRAS_G13D PTCH1 67 38 Metastasis -0.01 -1.25 0.78 241.32 1.02 784 65 36 2 TRUE 0.00
colorectal cancer KRAS_G13D PTCH1 111 107 Primary 0.48 -0.10 1.04 1151.81 1.00 1161 97 93 14 TRUE 0.99
colorectal cancer KRAS_G13D PTCH1 178 145 Tumor Type:overall 0.25 -1.15 1.38 1155.59 1.00 1945 162 129 16 TRUE 0.16
colorectal cancer KRAS_G13D TET1 66 35 Metastasis 0.54 -0.23 1.25 1283.41 1.00 791 61 30 5 FALSE 0.82
colorectal cancer KRAS_G13D TET1 111 68 Primary 0.48 -0.19 1.10 1319.73 1.00 1186 103 60 8 FALSE 0.83
colorectal cancer KRAS_G13D TET1 177 103 Tumor Type:overall 0.51 -0.31 1.33 1157.60 1.00 1977 164 90 13 FALSE 0.65
colorectal cancer KRAS_G13D FGFR2 69 19 Metastasis 0.21 -1.11 1.17 1348.66 1.00 867 68 18 1 TRUE 0.14
colorectal cancer KRAS_G13D FGFR2 118 34 Primary 0.42 -0.50 1.22 1484.32 1.00 1354 113 29 5 TRUE 0.45
colorectal cancer KRAS_G13D FGFR2 187 53 Tumor Type:overall 0.31 -0.94 1.34 1431.05 1.00 2221 181 47 6 TRUE 0.23
colorectal cancer KRAS_G13D TBX3 66 18 Metastasis -0.04 -1.34 1.15 1431.62 1.00 797 64 16 2 FALSE 0.02
colorectal cancer KRAS_G13D TBX3 106 62 Primary -0.21 -1.30 0.68 1203.17 1.00 1189 102 58 4 FALSE 0.18
colorectal cancer KRAS_G13D TBX3 172 80 Tumor Type:overall -0.14 -1.77 1.32 1390.44 1.00 1986 166 74 6 FALSE 0.07
colorectal cancer KRAS_G13D HNF1A 116 43 Primary 0.09 -1.10 1.09 1517.34 1.00 1343 112 39 4 TRUE 0.05
colorectal cancer KRAS_G13D HNF1A 116 43 Tumor Type:overall 0.16 -4.05 4.44 1300.24 1.00 1343 112 39 4 TRUE 0.03
colorectal cancer KRAS_G13D DICER1 66 27 Metastasis 0.44 -0.58 1.24 1345.41 1.00 792 64 25 2 TRUE 0.46
colorectal cancer KRAS_G13D DICER1 109 49 Primary 0.61 -0.21 1.34 1333.78 1.00 1200 101 41 8 TRUE 0.96
colorectal cancer KRAS_G13D DICER1 175 76 Tumor Type:overall 0.54 -0.40 1.40 1241.87 1.00 1992 165 66 10 TRUE 0.59
colorectal cancer KRAS_G13D SMAD3 66 38 Metastasis -0.22 -1.17 0.65 963.20 1.00 780 63 35 3 TRUE 0.19
colorectal cancer KRAS_G13D SMAD3 105 69 Primary -0.28 -1.20 0.49 959.50 1.00 1182 101 65 4 TRUE 0.29
colorectal cancer KRAS_G13D SMAD3 171 107 Tumor Type:overall -0.25 -1.21 0.61 1008.12 1.00 1962 164 100 7 TRUE 0.23
colorectal cancer KRAS_G13D NTRK3 66 15 Metastasis -0.49 -2.31 0.95 1338.05 1.00 800 65 14 1 FALSE 0.27
colorectal cancer KRAS_G13D NTRK3 105 55 Primary -0.48 -1.66 0.53 1386.17 1.00 1190 102 52 3 FALSE 0.40
colorectal cancer KRAS_G13D NTRK3 171 70 Tumor Type:overall -0.46 -2.24 1.15 1438.93 1.00 1990 167 66 4 FALSE 0.24
colorectal cancer KRAS_G13D AXIN1 66 17 Metastasis -0.05 -1.68 1.09 1547.40 1.00 799 65 16 1 FALSE 0.03
colorectal cancer KRAS_G13D AXIN1 106 54 Primary 0.24 -0.73 1.06 1419.05 1.00 1193 100 48 6 FALSE 0.23
colorectal cancer KRAS_G13D AXIN1 172 71 Tumor Type:overall 0.11 -1.37 1.39 1586.73 1.00 1992 165 64 7 FALSE 0.06
colorectal cancer KRAS_G13D GRIN2A 66 41 Metastasis -0.25 -1.39 0.58 1436.10 1.00 774 64 39 2 FALSE 0.22
colorectal cancer KRAS_G13D GRIN2A 106 95 Primary -0.06 -0.82 0.62 867.52 1.00 1161 98 87 8 FALSE 0.06
colorectal cancer KRAS_G13D GRIN2A 172 136 Tumor Type:overall -0.16 -1.27 0.80 1140.70 1.00 1935 162 126 10 FALSE 0.12
colorectal cancer KRAS_G13D PALB2 107 47 Primary 1.00 0.16 1.73 1348.01 1.00 1200 98 38 9 TRUE 1.97
colorectal cancer KRAS_G13D PALB2 107 47 Tumor Type:overall 0.80 -3.89 4.98 1547.73 1.00 1200 98 38 9 TRUE 0.15
colorectal cancer KRAS_G13D CTCF 66 24 Metastasis 0.02 -1.71 1.09 1437.06 1.00 793 65 23 1 FALSE 0.01
colorectal cancer KRAS_G13D CTCF 108 66 Primary 0.70 -0.01 1.34 1118.62 1.00 1187 97 55 11 FALSE 1.40
colorectal cancer KRAS_G13D CTCF 174 90 Tumor Type:overall 0.37 -1.13 1.64 1504.93 1.00 1980 162 78 12 FALSE 0.22
colorectal cancer KRAS_G13D CDH1 69 13 Metastasis -0.17 -1.76 1.10 1430.07 1.00 875 68 12 1 TRUE 0.09
colorectal cancer KRAS_G13D CDH1 116 41 Primary -0.16 -1.39 0.86 1251.94 1.00 1349 113 38 3 TRUE 0.10
colorectal cancer KRAS_G13D CDH1 185 54 Tumor Type:overall -0.15 -1.62 1.27 1395.93 1.00 2224 181 50 4 TRUE 0.08
colorectal cancer KRAS_G13D CDK12 67 21 Metastasis -0.17 -1.45 0.97 1536.62 1.00 797 65 19 2 FALSE 0.11
colorectal cancer KRAS_G13D CDK12 105 69 Primary -0.32 -1.39 0.56 1130.04 1.00 1180 101 65 4 FALSE 0.28
colorectal cancer KRAS_G13D CDK12 172 90 Tumor Type:overall -0.24 -1.64 1.09 1238.09 1.00 1977 166 84 6 FALSE 0.14
colorectal cancer KRAS_G13D DNMT1 66 27 Metastasis -0.08 -1.54 0.88 1334.62 1.00 790 65 26 1 FALSE 0.05
colorectal cancer KRAS_G13D DNMT1 105 63 Primary 0.34 -0.46 1.09 1132.61 1.00 1187 97 55 8 FALSE 0.40
colorectal cancer KRAS_G13D DNMT1 171 90 Tumor Type:overall 0.14 -1.27 1.31 1536.93 1.00 1977 162 81 9 FALSE 0.09
colorectal cancer KRAS_G13D BRD4 66 22 Metastasis -0.56 -2.13 0.62 1520.76 1.00 794 65 21 1 FALSE 0.38
colorectal cancer KRAS_G13D BRD4 105 66 Primary -0.41 -1.45 0.47 1337.74 1.00 1178 101 62 4 FALSE 0.38
colorectal cancer KRAS_G13D BRD4 171 88 Tumor Type:overall -0.48 -2.02 0.74 1454.87 1.00 1972 166 83 5 FALSE 0.32
colorectal cancer KRAS_G13D ASXL1 66 34 Metastasis 0.30 -0.49 1.07 1225.15 1.00 783 62 30 4 TRUE 0.34
colorectal cancer KRAS_G13D ASXL1 105 75 Primary 0.24 -0.49 0.94 1242.38 1.00 1177 98 68 7 TRUE 0.29
colorectal cancer KRAS_G13D ASXL1 171 109 Tumor Type:overall 0.28 -0.67 1.21 1401.60 1.00 1960 160 98 11 TRUE 0.24
colorectal cancer KRAS_G13D EP300 66 38 Metastasis -0.38 -2.03 0.56 1332.27 1.00 781 65 37 1 TRUE 0.26
colorectal cancer KRAS_G13D EP300 108 87 Primary 0.09 -0.62 0.81 1478.91 1.00 1173 99 78 9 TRUE 0.10
colorectal cancer KRAS_G13D EP300 174 125 Tumor Type:overall -0.17 -1.75 0.86 1383.38 1.00 1954 164 115 10 TRUE 0.10
colorectal cancer KRAS_G13D ERBB4 69 50 Metastasis 0.36 -0.75 1.11 1183.54 1.00 840 66 47 3 TRUE 0.33
colorectal cancer KRAS_G13D ERBB4 122 88 Primary 0.90 0.32 1.47 1125.17 1.00 1321 105 71 17 TRUE 2.63
colorectal cancer KRAS_G13D ERBB4 191 138 Tumor Type:overall 0.64 -0.41 1.53 1554.90 1.00 2161 171 118 20 TRUE 0.67
colorectal cancer KRAS_G13D MDC1 66 13 Metastasis 0.28 -1.33 1.48 1520.11 1.00 800 65 12 1 FALSE 0.15
colorectal cancer KRAS_G13D MDC1 108 52 Primary 0.81 0.00 1.52 1360.88 1.00 1198 99 43 9 FALSE 1.46
colorectal cancer KRAS_G13D MDC1 174 65 Tumor Type:overall 0.52 -1.27 2.15 1430.49 1.00 1998 164 55 10 FALSE 0.28
colorectal cancer KRAS_G13D RECQL4 66 20 Metastasis -0.33 -1.95 0.84 1307.80 1.00 796 65 19 1 TRUE 0.20
colorectal cancer KRAS_G13D RECQL4 105 61 Primary -0.09 -1.09 0.71 1618.80 1.00 1187 100 56 5 TRUE 0.07
colorectal cancer KRAS_G13D RECQL4 171 81 Tumor Type:overall -0.21 -1.77 1.02 1312.21 1.00 1983 165 75 6 TRUE 0.11
colorectal cancer KRAS_G13D MED12 66 28 Metastasis 0.37 -0.64 1.16 1438.37 1.00 793 63 25 3 TRUE 0.37
colorectal cancer KRAS_G13D MED12 108 80 Primary 0.50 -0.19 1.12 1306.72 1.00 1172 98 70 10 TRUE 0.86
colorectal cancer KRAS_G13D MED12 174 108 Tumor Type:overall 0.43 -0.76 1.47 1189.54 1.00 1965 161 95 13 TRUE 0.34
colorectal cancer KRAS_G13D ERCC5 66 14 Metastasis -0.83 -4.09 0.81 1288.05 1.00 799 66 14 0 TRUE 0.30
colorectal cancer KRAS_G13D ERCC5 105 44 Primary -0.12 -1.34 0.89 828.88 1.00 1199 101 40 4 TRUE 0.08
colorectal cancer KRAS_G13D ERCC5 171 58 Tumor Type:overall -0.45 -2.55 1.08 1082.87 1.01 1998 167 54 4 TRUE 0.19
colorectal cancer KRAS_G13D PIK3CD 66 24 Metastasis -0.29 -1.55 0.76 874.09 1.00 792 65 23 1 FALSE 0.19
colorectal cancer KRAS_G13D PIK3CD 105 45 Primary -0.14 -1.25 0.83 1004.85 1.00 1197 101 41 4 FALSE 0.10
colorectal cancer KRAS_G13D PIK3CD 171 69 Tumor Type:overall -0.22 -1.51 0.84 1078.01 1.00 1989 166 64 5 FALSE 0.13
colorectal cancer KRAS_G13D BRCA1 66 17 Metastasis 0.97 -0.02 1.93 1430.28 1.00 798 63 14 3 TRUE 1.28
colorectal cancer KRAS_G13D BRCA1 111 62 Primary 1.15 0.50 1.77 1570.80 1.00 1195 98 49 13 TRUE 3.51
colorectal cancer KRAS_G13D BRCA1 177 79 Tumor Type:overall 1.03 -0.24 2.29 1449.87 1.00 1993 161 63 16 TRUE 0.99
colorectal cancer KRAS_G13D RBM10 66 22 Metastasis -0.55 -2.05 0.57 1150.71 1.00 791 65 21 1 FALSE 0.40
colorectal cancer KRAS_G13D RBM10 105 50 Primary -0.47 -1.67 0.54 1321.48 1.00 1195 102 47 3 FALSE 0.38
colorectal cancer KRAS_G13D RBM10 171 72 Tumor Type:overall -0.49 -1.94 0.74 1368.25 1.00 1986 167 68 4 FALSE 0.32
colorectal cancer KRAS_G13D TSC1 66 16 Metastasis 0.30 -1.31 1.38 1161.21 1.00 800 65 15 1 TRUE 0.18
colorectal cancer KRAS_G13D TSC1 106 51 Primary 0.81 0.02 1.53 1463.84 1.00 1201 97 42 9 TRUE 1.47
colorectal cancer KRAS_G13D TSC1 172 67 Tumor Type:overall 0.55 -0.90 1.81 1270.96 1.00 2001 162 57 10 TRUE 0.37
colorectal cancer KRAS_G13D FLCN 66 18 Metastasis -1.28 -3.69 0.22 1247.37 1.00 797 66 18 0 TRUE 0.67
colorectal cancer KRAS_G13D FLCN 105 36 Primary -1.01 -2.79 0.35 1154.88 1.00 1204 103 34 2 TRUE 0.68
colorectal cancer KRAS_G13D FLCN 171 54 Tumor Type:overall -1.12 -3.19 0.38 1150.07 1.00 2001 169 52 2 TRUE 0.66
colorectal cancer KRAS_G13D NF1 66 37 Metastasis -0.23 -1.39 0.64 1436.78 1.00 783 64 35 2 TRUE 0.18
colorectal cancer KRAS_G13D NF1 108 105 Primary -0.01 -0.72 0.65 1391.26 1.00 1166 99 96 9 TRUE 0.01
colorectal cancer KRAS_G13D NF1 174 142 Tumor Type:overall -0.14 -1.36 0.94 1545.42 1.00 1949 163 131 11 TRUE 0.09
colorectal cancer KRAS_G13D FLT1 66 20 Metastasis 0.40 -0.63 1.51 1174.88 1.00 798 63 17 3 FALSE 0.33
colorectal cancer KRAS_G13D FLT1 105 62 Primary 0.11 -0.86 0.85 1411.53 1.00 1190 100 57 5 FALSE 0.10
colorectal cancer KRAS_G13D FLT1 171 82 Tumor Type:overall 0.23 -1.12 1.64 1381.98 1.00 1988 163 74 8 FALSE 0.13
colorectal cancer KRAS_G13D RPTOR 68 19 Metastasis 0.58 -0.54 1.73 992.42 1.00 799 64 15 4 FALSE 0.50
colorectal cancer KRAS_G13D RPTOR 105 51 Primary -0.02 -1.21 0.87 1137.17 1.00 1190 102 48 3 FALSE 0.01
colorectal cancer KRAS_G13D RPTOR 173 70 Tumor Type:overall 0.30 -1.03 1.78 1060.06 1.00 1989 166 63 7 FALSE 0.18
colorectal cancer KRAS_G13D RASA1 66 17 Metastasis -1.03 -4.51 0.62 1323.51 1.00 797 66 17 0 FALSE 0.35
colorectal cancer KRAS_G13D RASA1 105 56 Primary -0.10 -1.18 0.75 1317.35 1.00 1199 100 51 5 FALSE 0.08
colorectal cancer KRAS_G13D RASA1 171 73 Tumor Type:overall -0.56 -2.98 0.99 1463.57 1.00 1996 166 68 5 FALSE 0.24
colorectal cancer KRAS_G13D EPHA5 66 43 Metastasis -0.72 -2.34 0.29 1443.54 1.00 773 65 42 1 FALSE 0.56
colorectal cancer KRAS_G13D EPHA5 108 101 Primary -0.37 -1.22 0.38 1337.21 1.00 1161 101 94 7 FALSE 0.44
colorectal cancer KRAS_G13D EPHA5 174 144 Tumor Type:overall -0.53 -1.90 0.57 1558.82 1.00 1934 166 136 8 FALSE 0.40
colorectal cancer KRAS_G13D AR 66 21 Metastasis -0.33 -2.08 0.84 1503.52 1.00 792 65 20 1 TRUE 0.18
colorectal cancer KRAS_G13D AR 108 95 Primary 0.23 -0.47 0.90 1302.70 1.00 1160 98 85 10 TRUE 0.29
colorectal cancer KRAS_G13D AR 174 116 Tumor Type:overall -0.02 -2.00 1.60 1453.93 1.00 1952 163 105 11 TRUE 0.01
colorectal cancer KRAS_G13D GNAS 69 20 Metastasis 0.73 -0.54 1.61 1164.23 1.00 866 67 18 2 TRUE 0.75
colorectal cancer KRAS_G13D GNAS 118 55 Primary 1.12 0.46 1.78 1367.11 1.00 1341 106 43 12 TRUE 3.16
colorectal cancer KRAS_G13D GNAS 187 75 Tumor Type:overall 0.92 -0.30 1.92 1455.31 1.00 2207 173 61 14 TRUE 0.96
colorectal cancer KRAS_G13D ASXL2 66 15 Metastasis 0.04 -1.68 1.25 1288.00 1.00 800 65 14 1 FALSE 0.02
colorectal cancer KRAS_G13D ASXL2 108 56 Primary 0.41 -0.48 1.16 1226.78 1.00 1202 101 49 7 FALSE 0.48
colorectal cancer KRAS_G13D ASXL2 174 71 Tumor Type:overall 0.21 -1.44 1.54 1327.89 1.00 2002 166 63 8 FALSE 0.11
colorectal cancer KRAS_G13D SF3B1 72 21 Metastasis 2.06 1.14 3.02 1351.82 1.00 804 62 11 10 TRUE 4.55
colorectal cancer KRAS_G13D SF3B1 107 49 Primary 1.05 0.26 1.76 1413.31 1.00 1200 99 41 8 TRUE 2.15
colorectal cancer KRAS_G13D SF3B1 179 70 Tumor Type:overall 1.53 0.04 2.96 1554.97 1.00 2004 161 52 18 TRUE 1.39
colorectal cancer KRAS_G13D MLH1 69 12 Metastasis 0.78 -0.42 1.89 1368.21 1.00 874 67 10 2 TRUE 0.76
colorectal cancer KRAS_G13D MLH1 118 44 Primary 0.82 0.04 1.52 1288.52 1.00 1351 111 37 7 TRUE 1.42
colorectal cancer KRAS_G13D MLH1 187 56 Tumor Type:overall 0.80 -0.46 2.01 1483.65 1.00 2225 178 47 9 TRUE 0.69
colorectal cancer KRAS_G13D ROS1 66 33 Metastasis -0.08 -2.09 1.01 1131.43 1.00 786 65 32 1 TRUE 0.04
colorectal cancer KRAS_G13D ROS1 111 70 Primary 0.80 0.14 1.44 1397.66 1.00 1189 98 57 13 TRUE 1.77
colorectal cancer KRAS_G13D ROS1 177 103 Tumor Type:overall 0.36 -1.35 1.59 1381.29 1.00 1975 163 89 14 TRUE 0.21
colorectal cancer KRAS_G13D PIK3R2 105 42 Primary -0.28 -1.67 0.81 1187.29 1.00 1200 102 39 3 FALSE 0.18
colorectal cancer KRAS_G13D PIK3R2 105 42 Tumor Type:overall -0.25 -4.41 3.73 1469.83 1.00 1200 102 39 3 FALSE 0.05
colorectal cancer KRAS_G13D FLT3 69 13 Metastasis -0.65 -3.93 0.84 1331.08 1.00 874 69 13 0 TRUE 0.23
colorectal cancer KRAS_G13D FLT3 117 39 Primary 0.01 -1.18 1.02 1207.40 1.00 1351 113 35 4 TRUE 0.01
colorectal cancer KRAS_G13D FLT3 186 52 Tumor Type:overall -0.27 -2.15 1.12 1292.15 1.00 2225 182 48 4 TRUE 0.13
colorectal cancer KRAS_G13D MSH2 69 22 Metastasis 0.77 -0.33 1.85 847.83 1.00 797 64 17 5 TRUE 0.75
colorectal cancer KRAS_G13D MSH2 105 61 Primary -0.19 -1.41 0.71 1199.45 1.00 1194 102 58 3 TRUE 0.14
colorectal cancer KRAS_G13D MSH2 174 83 Tumor Type:overall 0.30 -1.17 1.75 1406.91 1.00 1991 166 75 8 TRUE 0.16
colorectal cancer KRAS_G13D AXL 67 22 Metastasis 0.75 -0.27 1.61 1352.58 1.00 796 64 19 3 FALSE 0.96
colorectal cancer KRAS_G13D AXL 108 66 Primary 0.93 0.24 1.56 1324.18 1.00 1189 96 54 12 FALSE 2.33
colorectal cancer KRAS_G13D AXL 175 88 Tumor Type:overall 0.82 -0.37 1.95 1541.92 1.00 1985 160 73 15 FALSE 0.79
colorectal cancer KRAS_G13D PIK3CG 66 34 Metastasis -0.43 -1.85 0.45 154.47 1.03 782 65 33 1 FALSE 0.32
colorectal cancer KRAS_G13D PIK3CG 107 73 Primary -0.18 -1.04 0.58 309.77 1.01 1178 101 67 6 FALSE 0.17
colorectal cancer KRAS_G13D PIK3CG 173 107 Tumor Type:overall -0.32 -1.58 0.60 299.86 1.01 1960 166 100 7 FALSE 0.23
colorectal cancer KRAS_G13D MAP2K4 66 24 Metastasis 0.58 -0.30 1.47 906.24 1.00 793 62 20 4 TRUE 0.73
colorectal cancer KRAS_G13D MAP2K4 106 39 Primary 0.47 -0.41 1.21 852.81 1.00 1201 102 35 4 TRUE 0.61
colorectal cancer KRAS_G13D MAP2K4 172 63 Tumor Type:overall 0.52 -0.41 1.34 972.04 1.00 1994 164 55 8 TRUE 0.62
colorectal cancer KRAS_G13D EGFR 70 16 Metastasis 0.06 -1.20 1.29 1219.95 1.00 871 68 14 2 TRUE 0.04
colorectal cancer KRAS_G13D EGFR 116 50 Primary -0.17 -1.24 0.77 1358.86 1.00 1339 113 47 3 TRUE 0.13
colorectal cancer KRAS_G13D EGFR 186 66 Tumor Type:overall -0.05 -1.35 1.23 1513.80 1.00 2210 181 61 5 TRUE 0.03
colorectal cancer KRAS_G13D ARID1B 66 35 Metastasis -0.21 -1.32 0.71 1474.68 1.00 784 64 33 2 TRUE 0.16
colorectal cancer KRAS_G13D ARID1B 105 105 Primary 0.03 -0.70 0.70 1520.84 1.00 1157 96 96 9 TRUE 0.03
colorectal cancer KRAS_G13D ARID1B 171 140 Tumor Type:overall -0.09 -1.53 1.12 1520.67 1.00 1941 160 129 11 TRUE 0.05
colorectal cancer KRAS_G13D ARID5B 66 15 Metastasis -0.44 -2.06 0.82 1509.00 1.00 799 65 14 1 FALSE 0.25
colorectal cancer KRAS_G13D ARID5B 106 53 Primary -0.46 -1.73 0.56 1439.05 1.00 1197 103 50 3 FALSE 0.37
colorectal cancer KRAS_G13D ARID5B 172 68 Tumor Type:overall -0.42 -2.01 1.12 1503.00 1.00 1996 168 64 4 FALSE 0.22
colorectal cancer KRAS_G13D BRAF 69 79 Metastasis -1.33 -2.72 -0.40 1253.34 1.00 809 68 78 1 TRUE 1.59
colorectal cancer KRAS_G13D BRAF 116 174 Primary -0.97 -1.79 -0.27 1415.30 1.00 1224 109 167 7 TRUE 1.85
colorectal cancer KRAS_G13D BRAF 185 253 Tumor Type:overall -1.14 -2.35 -0.17 1393.14 1.00 2033 177 245 8 TRUE 1.27
colorectal cancer KRAS_G13D B2M 67 15 Metastasis 0.44 -1.11 1.65 1416.29 1.00 803 65 13 2 FALSE 0.28
colorectal cancer KRAS_G13D B2M 110 124 Primary 0.42 -0.20 0.97 1569.02 1.00 1167 96 110 14 FALSE 0.82
colorectal cancer KRAS_G13D B2M 177 139 Tumor Type:overall 0.44 -1.51 2.36 1515.91 1.00 1970 161 123 16 FALSE 0.19
colorectal cancer KRAS_G13D TGFBR1 66 13 Metastasis -0.64 -4.11 1.02 995.82 1.00 801 66 13 0 FALSE 0.17
colorectal cancer KRAS_G13D TGFBR1 106 38 Primary 0.29 -0.85 1.25 1452.15 1.00 1206 101 33 5 FALSE 0.24
colorectal cancer KRAS_G13D TGFBR1 172 51 Tumor Type:overall -0.14 -2.72 1.52 1264.24 1.00 2007 167 46 5 FALSE 0.05
colorectal cancer KRAS_G13D TET2 66 14 Metastasis -1.26 -5.61 0.94 1329.57 1.00 800 66 14 0 TRUE 0.31
colorectal cancer KRAS_G13D TET2 109 77 Primary 0.56 -0.17 1.24 1485.21 1.00 1181 98 66 11 TRUE 0.94
colorectal cancer KRAS_G13D TET2 175 91 Tumor Type:overall -0.30 -3.58 1.76 1476.93 1.00 1981 164 80 11 TRUE 0.08
colorectal cancer KRAS_G13D PDGFRB 105 46 Primary 0.30 -0.80 1.19 1369.16 1.00 1195 100 41 5 TRUE 0.25
colorectal cancer KRAS_G13D PDGFRB 105 46 Tumor Type:overall 0.26 -3.81 4.62 1358.27 1.00 1195 100 41 5 TRUE 0.05
colorectal cancer KRAS_G13D CARD11 67 29 Metastasis 0.16 -0.95 1.13 1660.10 1.00 788 64 26 3 FALSE 0.12
colorectal cancer KRAS_G13D CARD11 107 99 Primary 0.14 -0.62 0.81 1643.74 1.00 1153 98 90 9 FALSE 0.16
colorectal cancer KRAS_G13D CARD11 174 128 Tumor Type:overall 0.16 -1.22 1.45 1476.87 1.00 1941 162 116 12 FALSE 0.10
colorectal cancer KRAS_G13D DNMT3A 66 11 Metastasis 0.11 -1.58 1.42 1405.86 1.00 802 65 10 1 TRUE 0.05
colorectal cancer KRAS_G13D DNMT3A 106 45 Primary 0.30 -0.65 1.16 1444.67 1.00 1201 101 40 5 TRUE 0.28
colorectal cancer KRAS_G13D DNMT3A 172 56 Tumor Type:overall 0.21 -1.53 1.62 1444.01 1.00 2003 166 50 6 TRUE 0.10
colorectal cancer KRAS_G13D MSH6 66 23 Metastasis -1.31 -5.40 0.47 1118.38 1.00 792 66 23 0 TRUE 0.41
colorectal cancer KRAS_G13D MSH6 107 77 Primary 0.14 -0.71 0.89 1408.87 1.00 1180 99 69 8 TRUE 0.13
colorectal cancer KRAS_G13D MSH6 173 100 Tumor Type:overall -0.57 -3.32 1.42 1513.47 1.00 1972 165 92 8 TRUE 0.20
colorectal cancer KRAS_G13D SOX9 66 72 Metastasis -0.32 -1.47 0.54 1502.94 1.00 749 63 69 3 FALSE 0.27
colorectal cancer KRAS_G13D SOX9 107 192 Primary 0.76 0.28 1.21 1341.35 1.00 1088 79 164 28 FALSE 2.83
colorectal cancer KRAS_G13D SOX9 173 264 Tumor Type:overall 0.20 -1.39 1.68 1526.97 1.00 1837 142 233 31 FALSE 0.11
colorectal cancer KRAS_G13D ETV1 66 14 Metastasis 0.46 -0.93 1.47 969.05 1.00 799 65 13 1 TRUE 0.33
colorectal cancer KRAS_G13D ETV1 106 38 Primary 0.81 -0.06 1.57 887.17 1.00 1207 99 31 7 TRUE 1.27
colorectal cancer KRAS_G13D ETV1 172 52 Tumor Type:overall 0.61 -0.82 1.73 1168.07 1.00 2006 164 44 8 TRUE 0.45
colorectal cancer KRAS_G13D ARAF 66 18 Metastasis -0.35 -3.30 0.98 665.02 1.00 794 66 18 0 FALSE 0.12
colorectal cancer KRAS_G13D ARAF 106 37 Primary 0.21 -0.89 1.17 597.52 1.01 1208 101 32 5 FALSE 0.17
colorectal cancer KRAS_G13D ARAF 172 55 Tumor Type:overall -0.05 -1.93 1.20 800.99 1.00 2002 167 50 5 FALSE 0.02
colorectal cancer KRAS_G13D SMAD2 67 26 Metastasis 0.13 -0.92 1.09 35.77 1.06 789 65 24 2 TRUE 0.09
colorectal cancer KRAS_G13D SMAD2 106 76 Primary 0.39 -0.57 1.18 17.76 1.14 1178 96 66 10 TRUE 0.39
colorectal cancer KRAS_G13D SMAD2 173 102 Tumor Type:overall 0.27 -0.97 1.47 50.45 1.05 1967 161 90 12 TRUE 0.17
colorectal cancer KRAS_G13D JUN 66 16 Metastasis -0.91 -3.55 0.64 1015.68 1.00 797 66 16 0 FALSE 0.31
colorectal cancer KRAS_G13D JUN 105 37 Primary -0.42 -1.81 0.75 840.72 1.00 1204 102 34 3 FALSE 0.28
colorectal cancer KRAS_G13D JUN 171 53 Tumor Type:overall -0.66 -2.65 0.82 982.14 1.00 2001 168 50 3 FALSE 0.33
colorectal cancer KRAS_G13D DNMT3B 66 15 Metastasis -0.22 -1.67 1.04 1372.37 1.00 799 65 14 1 FALSE 0.12
colorectal cancer KRAS_G13D DNMT3B 105 49 Primary -0.08 -1.11 0.84 1527.31 1.00 1197 101 45 4 FALSE 0.06
colorectal cancer KRAS_G13D DNMT3B 171 64 Tumor Type:overall -0.17 -1.67 1.13 1415.71 1.00 1996 166 59 5 FALSE 0.09
colorectal cancer KRAS_G13D FGFR1 69 17 Metastasis -1.19 -3.62 0.41 744.73 1.01 869 69 17 0 TRUE 0.57
colorectal cancer KRAS_G13D FGFR1 116 34 Primary -0.94 -2.72 0.50 643.64 1.01 1353 114 32 2 TRUE 0.58
colorectal cancer KRAS_G13D FGFR1 185 51 Tumor Type:overall -1.04 -3.06 0.46 547.81 1.01 2222 183 49 2 TRUE 0.60
colorectal cancer KRAS_G13D MITF 66 14 Metastasis -0.70 -3.90 0.82 760.56 1.00 798 66 14 0 FALSE 0.25
colorectal cancer KRAS_G13D MITF 105 38 Primary -0.01 -1.17 0.99 937.08 1.00 1202 101 34 4 FALSE 0.01
colorectal cancer KRAS_G13D MITF 171 52 Tumor Type:overall -0.34 -2.64 1.04 879.65 1.00 2000 167 48 4 FALSE 0.15
colorectal cancer KRAS_G13D SH2B3 93 46 Primary -0.20 -1.64 0.82 115.94 1.02 1101 90 43 3 FALSE 0.13
colorectal cancer KRAS_G13D SH2B3 93 46 Tumor Type:overall -0.12 -4.12 4.05 1362.27 1.00 1101 90 43 3 FALSE 0.02
colorectal cancer KRAS_G13D GLI1 61 24 Metastasis 0.10 -1.00 0.99 879.33 1.00 709 59 22 2 FALSE 0.07
colorectal cancer KRAS_G13D GLI1 95 63 Primary 0.18 -0.67 0.91 1017.47 1.00 1087 89 57 6 FALSE 0.18
colorectal cancer KRAS_G13D GLI1 156 87 Tumor Type:overall 0.13 -0.95 1.04 1226.56 1.00 1796 148 79 8 FALSE 0.10
colorectal cancer KRAS_G13D ZFHX3 62 52 Metastasis 0.04 -0.85 0.87 1572.74 1.00 696 57 47 5 FALSE 0.03
colorectal cancer KRAS_G13D ZFHX3 97 174 Primary -0.20 -0.80 0.38 1388.29 1.00 1025 86 163 11 FALSE 0.29
colorectal cancer KRAS_G13D ZFHX3 159 226 Tumor Type:overall -0.05 -1.30 1.18 1527.31 1.00 1721 143 210 16 FALSE 0.03
colorectal cancer KRAS_G13D MST1R 61 19 Metastasis -0.18 -1.66 0.90 1236.09 1.00 714 60 18 1 FALSE 0.10
colorectal cancer KRAS_G13D MST1R 93 54 Primary 0.06 -0.96 0.93 1391.05 1.00 1100 88 49 5 FALSE 0.05
colorectal cancer KRAS_G13D MST1R 154 73 Tumor Type:overall -0.07 -1.59 1.10 1453.73 1.00 1814 148 67 6 FALSE 0.04
colorectal cancer KRAS_G13D MGA 61 29 Metastasis 0.51 -0.39 1.38 1362.78 1.00 705 57 25 4 FALSE 0.59
colorectal cancer KRAS_G13D MGA 97 94 Primary 0.49 -0.22 1.09 1229.39 1.00 1067 86 83 11 FALSE 0.85
colorectal cancer KRAS_G13D MGA 158 123 Tumor Type:overall 0.50 -0.62 1.64 1523.43 1.00 1772 143 108 15 FALSE 0.40
colorectal cancer KRAS_G13D TCF3 61 13 Metastasis 0.04 -1.62 1.32 1473.15 1.00 719 60 12 1 FALSE 0.02
colorectal cancer KRAS_G13D TCF3 93 55 Primary 0.32 -0.63 1.14 1370.33 1.00 1094 87 49 6 FALSE 0.32
colorectal cancer KRAS_G13D TCF3 154 68 Tumor Type:overall 0.16 -1.59 1.70 1494.39 1.00 1813 147 61 7 FALSE 0.07
colorectal cancer KRAS_G13D KMT2B 34 39 Metastasis 0.56 -0.22 1.31 1404.72 1.00 312 28 33 6 FALSE 0.80
colorectal cancer KRAS_G13D KMT2B 59 143 Primary 0.50 -0.06 1.05 1162.27 1.00 633 44 128 15 FALSE 1.08
colorectal cancer KRAS_G13D KMT2B 93 182 Tumor Type:overall 0.51 -0.47 1.49 1442.59 1.00 945 72 161 21 FALSE 0.48
colorectal cancer KRAS_G13D TCF7L2 63 97 Metastasis 0.22 -0.35 0.84 1366.28 1.00 649 52 86 11 FALSE 0.33
colorectal cancer KRAS_G13D TCF7L2 95 202 Primary 0.01 -0.54 0.52 1425.12 1.00 968 81 188 14 FALSE 0.01
colorectal cancer KRAS_G13D TCF7L2 158 299 Tumor Type:overall 0.11 -0.72 0.91 899.04 1.00 1617 133 274 25 FALSE 0.11
colorectal cancer KRAS_G13D MSH3 32 18 Metastasis -1.03 -4.92 0.61 1322.22 1.00 315 32 18 0 FALSE 0.35
colorectal cancer KRAS_G13D MSH3 56 71 Primary 0.11 -0.80 0.96 1483.27 1.00 661 49 64 7 FALSE 0.10
colorectal cancer KRAS_G13D MSH3 88 89 Tumor Type:overall -0.43 -2.95 1.17 1405.82 1.00 976 81 82 7 FALSE 0.17
colorectal cancer KRAS_G13D ANKRD11 61 36 Metastasis -0.53 -2.52 0.68 1516.71 1.00 704 60 35 1 FALSE 0.29
colorectal cancer KRAS_G13D ANKRD11 95 110 Primary 0.41 -0.20 1.02 1466.10 1.00 1065 82 97 13 FALSE 0.69
colorectal cancer KRAS_G13D ANKRD11 156 146 Tumor Type:overall -0.07 -2.02 1.44 1494.00 1.00 1769 142 132 14 FALSE 0.03
colorectal cancer KRAS_G13D PGR 61 11 Metastasis -1.12 -5.25 0.94 1414.32 1.00 720 61 11 0 FALSE 0.32
colorectal cancer KRAS_G13D PGR 95 52 Primary 0.02 -1.10 0.93 1501.47 1.00 1094 90 47 5 FALSE 0.01
colorectal cancer KRAS_G13D PGR 156 63 Tumor Type:overall -0.50 -3.49 1.70 1446.64 1.00 1814 151 58 5 FALSE 0.16
colorectal cancer KRAS_G13D PLCG2 62 22 Metastasis 0.28 -0.78 1.23 1353.11 1.00 712 59 19 3 FALSE 0.23
colorectal cancer KRAS_G13D PLCG2 95 63 Primary 0.10 -0.79 0.88 1408.92 1.00 1084 90 58 5 FALSE 0.08
colorectal cancer KRAS_G13D PLCG2 157 85 Tumor Type:overall 0.19 -1.00 1.31 1445.27 1.00 1796 149 77 8 FALSE 0.13
colorectal cancer KRAS_G13D POLD1 61 20 Metastasis -0.25 -1.92 1.00 1463.31 1.00 715 60 19 1 TRUE 0.13
colorectal cancer KRAS_G13D POLD1 95 92 Primary 0.34 -0.43 1.02 1428.74 1.00 1077 85 82 10 TRUE 0.45
colorectal cancer KRAS_G13D POLD1 156 112 Tumor Type:overall 0.06 -1.78 1.65 1346.62 1.00 1792 145 101 11 TRUE 0.03
colorectal cancer KRAS_G13D INHBA 61 20 Metastasis -2.09 -5.15 -0.08 950.24 1.00 710 61 20 0 FALSE 0.95
colorectal cancer KRAS_G13D INHBA 93 34 Primary -1.93 -4.64 -0.02 794.51 1.00 1106 92 33 1 FALSE 1.00
colorectal cancer KRAS_G13D INHBA 154 54 Tumor Type:overall -1.99 -4.78 0.03 909.40 1.00 1816 153 53 1 FALSE 0.97
colorectal cancer KRAS_G13D PREX2 36 31 Metastasis 0.44 -0.51 1.35 854.38 1.00 308 30 25 6 FALSE 0.43
colorectal cancer KRAS_G13D PREX2 55 60 Primary -0.03 -1.17 0.85 1029.37 1.00 667 52 57 3 FALSE 0.02
colorectal cancer KRAS_G13D PREX2 91 91 Tumor Type:overall 0.21 -1.06 1.42 1167.78 1.00 975 82 82 9 FALSE 0.14
colorectal cancer KRAS_G13D AMER1 66 51 Metastasis 0.36 -0.57 1.07 428.04 1.01 767 62 47 4 FALSE 0.39
colorectal cancer KRAS_G13D AMER1 110 118 Primary 0.70 0.07 1.21 446.10 1.01 1142 92 100 18 FALSE 1.74
colorectal cancer KRAS_G13D AMER1 176 169 Tumor Type:overall 0.52 -0.47 1.37 778.09 1.01 1909 154 147 22 FALSE 0.53
colorectal cancer KRAS_G13D HLA-A 94 42 Primary 0.42 -0.62 1.34 1418.85 1.00 1107 89 37 5 FALSE 0.39
colorectal cancer KRAS_G13D HLA-A 94 42 Tumor Type:overall 0.42 -4.28 4.51 1373.67 1.00 1107 89 37 5 FALSE 0.08
colorectal cancer KRAS_G13D EPHA7 61 23 Metastasis -0.57 -2.18 0.61 1312.54 1.00 708 60 22 1 FALSE 0.38
colorectal cancer KRAS_G13D EPHA7 94 67 Primary -0.41 -1.48 0.48 1401.62 1.00 1085 90 63 4 FALSE 0.38
colorectal cancer KRAS_G13D EPHA7 155 90 Tumor Type:overall -0.49 -1.88 0.80 1316.81 1.00 1793 150 85 5 FALSE 0.30
colorectal cancer KRAS_G13D NCOA3 61 14 Metastasis -0.81 -4.34 0.79 1087.68 1.01 717 61 14 0 TRUE 0.28
colorectal cancer KRAS_G13D NCOA3 93 42 Primary -0.07 -1.26 0.92 1121.06 1.00 1102 89 38 4 TRUE 0.05
colorectal cancer KRAS_G13D NCOA3 154 56 Tumor Type:overall -0.46 -2.99 1.08 1235.95 1.00 1819 150 52 4 TRUE 0.18
colorectal cancer KRAS_G13D SLX4 32 13 Metastasis -0.95 -3.64 0.63 1232.10 1.00 319 32 13 0 FALSE 0.35
colorectal cancer KRAS_G13D SLX4 55 41 Primary -0.44 -1.86 0.74 1514.59 1.00 682 52 38 3 FALSE 0.29
colorectal cancer KRAS_G13D SLX4 87 54 Tumor Type:overall -0.66 -2.68 0.86 1319.37 1.00 1001 84 51 3 FALSE 0.33
colorectal cancer KRAS_G13D INPPL1 32 15 Metastasis -0.90 -5.03 0.91 903.71 1.00 320 32 15 0 FALSE 0.24
colorectal cancer KRAS_G13D INPPL1 57 58 Primary 0.72 -0.17 1.51 753.84 1.00 678 48 49 9 FALSE 1.05
colorectal cancer KRAS_G13D INPPL1 89 73 Tumor Type:overall -0.09 -3.04 1.78 1323.00 1.00 998 80 64 9 FALSE 0.03
melanoma NRAS_Q61K SPEN 50 92 Metastasis -0.53 -1.69 0.25 34.74 1.08 553 46 88 4 FALSE 0.52
melanoma NRAS_Q61K SPEN 10 25 Primary -0.45 -2.05 0.80 370.13 1.02 214 9 24 1 FALSE 0.29
melanoma NRAS_Q61K SPEN 60 117 Tumor Type:overall -0.49 -2.01 0.72 127.05 1.03 767 55 112 5 FALSE 0.32
melanoma NRAS_Q61K KMT2C 51 122 Metastasis -0.52 -1.40 0.26 1428.60 1.00 524 45 116 6 FALSE 0.64
melanoma NRAS_Q61K KMT2C 10 27 Primary -0.46 -1.95 0.98 1626.74 1.00 212 9 26 1 FALSE 0.27
melanoma NRAS_Q61K KMT2C 61 149 Tumor Type:overall -0.52 -2.00 0.98 1524.28 1.00 736 54 142 7 FALSE 0.30
melanoma NRAS_Q61K TP53 53 162 Metastasis 0.34 -0.29 0.94 1186.01 1.00 499 37 146 16 TRUE 0.56
melanoma NRAS_Q61K TP53 10 48 Primary 0.14 -0.97 1.04 1445.31 1.00 197 8 46 2 TRUE 0.11
melanoma NRAS_Q61K TP53 63 210 Tumor Type:overall 0.22 -1.04 1.30 1581.95 1.00 696 45 192 18 TRUE 0.15
melanoma NRAS_Q61K ATRX 51 78 Metastasis -0.22 -1.29 0.64 779.84 1.01 562 45 72 6 TRUE 0.18
melanoma NRAS_Q61K ATRX 10 30 Primary -0.86 -3.98 0.65 1279.66 1.00 209 10 30 0 TRUE 0.30
melanoma NRAS_Q61K ATRX 61 108 Tumor Type:overall -0.51 -2.88 0.98 1163.09 1.00 771 55 102 6 TRUE 0.23
melanoma NRAS_Q61K ATR 50 49 Metastasis -0.63 -2.00 0.52 1018.09 1.00 571 48 47 2 FALSE 0.46
melanoma NRAS_Q61K ATR 10 16 Primary -0.46 -2.25 1.06 1500.85 1.00 218 9 15 1 FALSE 0.24
melanoma NRAS_Q61K ATR 60 65 Tumor Type:overall -0.56 -2.44 0.95 1269.92 1.00 789 57 62 3 FALSE 0.29
melanoma NRAS_Q61K PDGFRA 52 66 Metastasis -1.33 -3.16 -0.07 1507.71 1.00 575 50 64 2 TRUE 1.04
melanoma NRAS_Q61K PDGFRA 10 12 Primary -1.71 -5.17 0.50 1305.15 1.00 224 10 12 0 TRUE 0.62
melanoma NRAS_Q61K PDGFRA 62 78 Tumor Type:overall -1.49 -4.07 0.63 1483.54 1.00 799 60 76 2 TRUE 0.67
melanoma NRAS_Q61K NSD1 50 45 Metastasis -0.95 -2.84 0.41 873.12 1.00 577 48 43 2 FALSE 0.62
melanoma NRAS_Q61K NSD1 10 12 Primary -1.28 -4.27 0.68 1122.14 1.00 218 10 12 0 FALSE 0.51
melanoma NRAS_Q61K NSD1 60 57 Tumor Type:overall -1.09 -3.51 0.86 904.43 1.00 795 58 55 2 FALSE 0.50
melanoma NRAS_Q61K FLT4 50 74 Metastasis -1.06 -2.58 0.12 1382.12 1.00 553 48 72 2 TRUE 0.92
melanoma NRAS_Q61K FLT4 10 19 Primary -0.74 -2.55 1.02 1314.77 1.00 217 9 18 1 TRUE 0.40
melanoma NRAS_Q61K FLT4 60 93 Tumor Type:overall -0.87 -2.62 0.80 1345.31 1.00 770 57 90 3 TRUE 0.49
melanoma NRAS_Q61K PTPRD 51 204 Metastasis -1.12 -2.16 -0.28 1116.99 1.00 491 46 199 5 FALSE 1.79
melanoma NRAS_Q61K PTPRD 10 69 Primary -0.13 -1.44 1.39 994.86 1.01 190 6 65 4 FALSE 0.06
melanoma NRAS_Q61K PTPRD 61 273 Tumor Type:overall -0.62 -2.18 1.23 1397.82 1.00 681 52 264 9 FALSE 0.35
melanoma NRAS_Q61K RET 52 42 Metastasis -5.51 -12.46 -1.35 1319.64 1.00 587 52 42 0 TRUE 1.28
melanoma NRAS_Q61K RET 10 22 Primary -5.42 -12.32 -1.01 1338.90 1.00 220 10 22 0 TRUE 1.20
melanoma NRAS_Q61K RET 62 64 Tumor Type:overall -5.33 -11.96 -0.98 1327.23 1.00 807 62 64 0 TRUE 1.21
melanoma NRAS_Q61K PIK3C2G 52 150 Metastasis -0.52 -1.35 0.24 1263.78 1.00 514 45 143 7 FALSE 0.71
melanoma NRAS_Q61K PIK3C2G 10 46 Primary -0.37 -1.59 0.86 1134.12 1.00 204 8 44 2 FALSE 0.26
melanoma NRAS_Q61K PIK3C2G 62 196 Tumor Type:overall -0.42 -1.73 0.94 1365.85 1.00 718 53 187 9 FALSE 0.29
melanoma NRAS_Q61K CREBBP 50 55 Metastasis -1.17 -2.93 0.11 1374.88 1.00 570 48 53 2 TRUE 0.91
melanoma NRAS_Q61K CREBBP 10 17 Primary -1.45 -4.16 0.36 1289.23 1.00 216 10 17 0 TRUE 0.64
melanoma NRAS_Q61K CREBBP 60 72 Tumor Type:overall -1.31 -3.35 0.33 1289.01 1.00 786 58 70 2 TRUE 0.74
melanoma NRAS_Q61K DOT1L 50 42 Metastasis -1.83 -4.60 0.00 1092.39 1.00 578 49 41 1 FALSE 0.94
melanoma NRAS_Q61K DOT1L 10 15 Primary -2.04 -5.48 0.15 1105.87 1.00 218 10 15 0 FALSE 0.79
melanoma NRAS_Q61K DOT1L 60 57 Tumor Type:overall -1.88 -5.03 0.41 1105.35 1.00 796 59 56 1 FALSE 0.78
melanoma NRAS_Q61K PTPRS 50 55 Metastasis -1.13 -2.83 0.15 1169.30 1.00 567 48 53 2 FALSE 0.83
melanoma NRAS_Q61K PTPRS 10 12 Primary -1.48 -4.84 0.59 1306.43 1.00 220 10 12 0 FALSE 0.50
melanoma NRAS_Q61K PTPRS 60 67 Tumor Type:overall -1.27 -3.78 0.72 1399.72 1.00 787 58 65 2 FALSE 0.58
melanoma NRAS_Q61K SMARCA4 50 54 Metastasis -0.61 -1.95 0.56 866.47 1.00 567 47 51 3 FALSE 0.45
melanoma NRAS_Q61K SMARCA4 10 18 Primary -0.99 -3.69 0.57 969.92 1.00 216 10 18 0 FALSE 0.42
melanoma NRAS_Q61K SMARCA4 60 72 Tumor Type:overall -0.79 -2.63 0.74 996.68 1.00 783 57 69 3 FALSE 0.42
melanoma NRAS_Q61K PTPRT 55 290 Metastasis 0.36 -0.19 0.89 1524.62 1.00 455 31 266 24 FALSE 0.74
melanoma NRAS_Q61K PTPRT 11 82 Primary 0.64 -0.20 1.76 1100.48 1.00 192 5 76 6 FALSE 0.74
melanoma NRAS_Q61K PTPRT 66 372 Tumor Type:overall 0.52 -0.57 1.86 1533.16 1.00 647 36 342 30 FALSE 0.40
melanoma NRAS_Q61K HGF 50 62 Metastasis -0.66 -2.21 0.35 1146.39 1.00 564 48 60 2 FALSE 0.52
melanoma NRAS_Q61K HGF 10 21 Primary -0.03 -1.44 1.56 1275.55 1.00 215 8 19 2 FALSE 0.01
melanoma NRAS_Q61K HGF 60 83 Tumor Type:overall -0.36 -1.98 1.24 1533.38 1.00 779 56 79 4 FALSE 0.19
melanoma NRAS_Q61K ALK 53 108 Metastasis -0.48 -1.48 0.34 1573.16 1.00 546 48 103 5 TRUE 0.53
melanoma NRAS_Q61K ALK 10 20 Primary 0.28 -1.25 1.86 1362.63 1.00 219 8 18 2 TRUE 0.14
melanoma NRAS_Q61K ALK 63 128 Tumor Type:overall -0.11 -1.93 1.78 1493.07 1.00 765 56 121 7 TRUE 0.04
melanoma NRAS_Q61K BAP1 50 45 Metastasis -0.99 -2.65 0.32 1288.85 1.00 574 48 43 2 TRUE 0.73
melanoma NRAS_Q61K BAP1 10 21 Primary -1.35 -4.30 0.37 1244.61 1.00 210 10 21 0 TRUE 0.59
melanoma NRAS_Q61K BAP1 60 66 Tumor Type:overall -1.12 -3.38 0.63 1336.41 1.00 784 58 64 2 TRUE 0.59
melanoma NRAS_Q61K PTEN 52 64 Metastasis 0.03 -1.00 0.88 819.17 1.00 569 47 59 5 TRUE 0.02
melanoma NRAS_Q61K PTEN 10 15 Primary 0.07 -1.32 1.46 1215.27 1.00 220 9 14 1 TRUE 0.04
melanoma NRAS_Q61K PTEN 62 79 Tumor Type:overall 0.07 -1.45 1.54 1295.32 1.00 789 56 73 6 TRUE 0.03
melanoma NRAS_Q61K CTNNB1 52 48 Metastasis 0.29 -0.76 1.25 1278.49 1.00 584 47 43 5 TRUE 0.24
melanoma NRAS_Q61K CTNNB1 52 48 Tumor Type:overall 0.18 -4.54 4.10 1236.49 1.00 584 47 43 5 TRUE 0.03
melanoma NRAS_Q61K ARID1A 51 76 Metastasis 0.13 -0.78 0.93 1416.07 1.00 556 44 69 7 TRUE 0.12
melanoma NRAS_Q61K ARID1A 10 13 Primary -0.72 -4.42 1.09 1369.18 1.00 218 10 13 0 TRUE 0.19
melanoma NRAS_Q61K ARID1A 61 89 Tumor Type:overall -0.28 -2.84 1.65 1383.03 1.00 774 54 82 7 TRUE 0.10
melanoma NRAS_Q61K IKZF1 50 87 Metastasis -0.75 -1.95 0.20 1379.61 1.00 550 46 83 4 TRUE 0.75
melanoma NRAS_Q61K IKZF1 10 22 Primary -1.23 -3.96 0.44 1289.26 1.00 218 10 22 0 TRUE 0.54
melanoma NRAS_Q61K IKZF1 60 109 Tumor Type:overall -0.95 -3.05 0.70 1190.46 1.00 768 56 105 4 TRUE 0.49
melanoma NRAS_Q61K TERT 54 509 Metastasis 1.18 0.51 1.90 1488.13 1.00 239 8 463 46 TRUE 2.80
melanoma NRAS_Q61K TERT 10 105 Primary 1.18 0.12 2.37 1321.84 1.00 154 3 98 7 TRUE 1.39
melanoma NRAS_Q61K TERT 64 614 Tumor Type:overall 1.15 -0.33 2.73 1293.70 1.00 393 11 561 53 TRUE 0.84
melanoma NRAS_Q61K FAT1 50 121 Metastasis 0.01 -0.75 0.73 1493.80 1.00 526 41 112 9 FALSE 0.01
melanoma NRAS_Q61K FAT1 10 28 Primary -0.15 -1.66 1.03 1558.30 1.00 213 9 27 1 FALSE 0.09
melanoma NRAS_Q61K FAT1 60 149 Tumor Type:overall -0.05 -1.55 1.28 1434.12 1.00 739 50 139 10 FALSE 0.02
melanoma NRAS_Q61K CIC 50 38 Metastasis -0.32 -1.70 0.84 1054.26 1.00 584 47 35 3 TRUE 0.20
melanoma NRAS_Q61K CIC 10 16 Primary -0.79 -3.62 0.82 1419.61 1.00 215 10 16 0 TRUE 0.30
melanoma NRAS_Q61K CIC 60 54 Tumor Type:overall -0.52 -2.56 1.09 1517.87 1.00 799 57 51 3 TRUE 0.24
melanoma NRAS_Q61K KDM6A 50 22 Metastasis -0.94 -3.12 0.73 1477.00 1.00 597 49 21 1 FALSE 0.46
melanoma NRAS_Q61K KDM6A 10 49 Primary -1.00 -3.23 0.70 1415.45 1.00 224 9 48 1 FALSE 0.47
melanoma NRAS_Q61K KDM6A 60 71 Tumor Type:overall -0.90 -3.29 1.76 1499.62 1.00 821 58 69 2 FALSE 0.32
melanoma NRAS_Q61K POLE 51 58 Metastasis 0.63 -0.25 1.45 1284.01 1.00 567 44 51 7 TRUE 0.87
melanoma NRAS_Q61K POLE 11 14 Primary 0.83 -0.37 2.04 1385.49 1.00 219 9 12 2 TRUE 0.73
melanoma NRAS_Q61K POLE 62 72 Tumor Type:overall 0.71 -0.55 2.05 1446.35 1.00 786 53 63 9 TRUE 0.56
melanoma NRAS_Q61K NOTCH2 50 56 Metastasis -0.10 -1.35 0.92 239.60 1.01 572 46 52 4 TRUE 0.06
melanoma NRAS_Q61K NOTCH2 50 56 Tumor Type:overall -0.04 -4.06 4.42 1057.17 1.00 572 46 52 4 TRUE 0.01
melanoma NRAS_Q61K KMT2A 51 104 Metastasis -0.13 -0.94 0.63 1603.31 1.00 544 43 96 8 FALSE 0.12
melanoma NRAS_Q61K KMT2A 10 36 Primary -0.99 -4.51 0.47 1144.20 1.00 208 10 36 0 FALSE 0.31
melanoma NRAS_Q61K KMT2A 61 140 Tumor Type:overall -0.51 -2.96 0.94 1275.21 1.00 752 53 132 8 FALSE 0.24
melanoma NRAS_Q61K PAK7 52 174 Metastasis -0.52 -1.25 0.19 1321.41 1.00 489 43 165 9 FALSE 0.79
melanoma NRAS_Q61K PAK7 10 44 Primary -0.70 -2.32 0.57 1432.84 1.00 204 9 43 1 FALSE 0.49
melanoma NRAS_Q61K PAK7 62 218 Tumor Type:overall -0.60 -2.01 0.78 1343.15 1.00 693 52 208 10 FALSE 0.39
melanoma NRAS_Q61K BRCA2 50 70 Metastasis -0.74 -2.21 0.26 723.33 1.01 561 48 68 2 TRUE 0.63
melanoma NRAS_Q61K BRCA2 10 22 Primary -0.11 -1.59 1.60 1069.93 1.00 217 8 20 2 TRUE 0.05
melanoma NRAS_Q61K BRCA2 60 92 Tumor Type:overall -0.40 -1.96 1.26 1348.02 1.00 778 56 88 4 TRUE 0.21
melanoma NRAS_Q61K NOTCH3 51 98 Metastasis 0.00 -0.83 0.67 1225.82 1.00 543 44 91 7 TRUE 0.00
melanoma NRAS_Q61K NOTCH3 10 32 Primary 0.11 -1.03 1.33 1572.79 1.00 211 8 30 2 TRUE 0.07
melanoma NRAS_Q61K NOTCH3 61 130 Tumor Type:overall 0.07 -1.09 1.43 1488.96 1.00 754 52 121 9 TRUE 0.04
melanoma NRAS_Q61K NOTCH4 51 115 Metastasis -0.08 -0.88 0.65 1490.31 1.00 537 42 106 9 TRUE 0.08
melanoma NRAS_Q61K NOTCH4 10 33 Primary -1.01 -4.65 0.62 1327.52 1.00 205 10 33 0 TRUE 0.33
melanoma NRAS_Q61K NOTCH4 61 148 Tumor Type:overall -0.55 -2.98 0.86 1502.04 1.00 742 52 139 9 TRUE 0.24
melanoma NRAS_Q61K CDKN2A 54 112 Metastasis 0.30 -0.39 0.97 1349.52 1.00 537 43 101 11 TRUE 0.41
melanoma NRAS_Q61K CDKN2A 10 17 Primary 0.17 -1.48 1.57 1600.31 1.00 219 9 16 1 TRUE 0.08
melanoma NRAS_Q61K CDKN2A 64 129 Tumor Type:overall 0.22 -1.35 1.59 1404.97 1.00 756 52 117 12 TRUE 0.11
melanoma NRAS_Q61K EPHB1 50 45 Metastasis -0.62 -2.02 0.61 712.18 1.01 578 48 43 2 FALSE 0.45
melanoma NRAS_Q61K EPHB1 10 21 Primary -0.49 -2.10 1.05 954.50 1.00 211 9 20 1 FALSE 0.26
melanoma NRAS_Q61K EPHB1 60 66 Tumor Type:overall -0.53 -2.27 1.14 615.00 1.00 789 57 63 3 FALSE 0.27
melanoma NRAS_Q61K IL7R 50 73 Metastasis -0.91 -2.31 0.16 161.08 1.02 558 47 70 3 FALSE 0.79
melanoma NRAS_Q61K IL7R 10 21 Primary -1.26 -4.01 0.32 423.33 1.01 215 10 21 0 FALSE 0.57
melanoma NRAS_Q61K IL7R 60 94 Tumor Type:overall -1.03 -3.07 0.53 266.39 1.02 773 57 91 3 FALSE 0.59
melanoma NRAS_Q61K ATM 52 57 Metastasis -0.72 -2.20 0.40 770.52 1.00 576 49 54 3 TRUE 0.56
melanoma NRAS_Q61K ATM 10 21 Primary -1.11 -4.00 0.64 1089.38 1.00 216 10 21 0 TRUE 0.46
melanoma NRAS_Q61K ATM 62 78 Tumor Type:overall -0.87 -2.89 0.74 1150.62 1.00 792 59 75 3 TRUE 0.46
melanoma NRAS_Q61K MAP2K1 50 50 Metastasis -0.03 -1.24 0.97 1271.00 1.00 572 46 46 4 TRUE 0.02
melanoma NRAS_Q61K MAP2K1 50 50 Tumor Type:overall -0.06 -4.45 3.86 1531.75 1.00 572 46 46 4 TRUE 0.01
melanoma NRAS_Q61K RB1 52 43 Metastasis 0.45 -0.63 1.39 1410.65 1.00 595 47 38 5 TRUE 0.40
melanoma NRAS_Q61K RB1 52 43 Tumor Type:overall 0.44 -4.24 4.91 1624.77 1.00 595 47 38 5 TRUE 0.08
melanoma NRAS_Q61K KMT2D 53 175 Metastasis 0.34 -0.26 0.90 1498.24 1.00 516 37 159 16 FALSE 0.59
melanoma NRAS_Q61K KMT2D 11 43 Primary 0.14 -0.97 1.13 1204.43 1.00 203 9 41 2 FALSE 0.11
melanoma NRAS_Q61K KMT2D 64 218 Tumor Type:overall 0.21 -0.98 1.22 1297.72 1.00 719 46 200 18 FALSE 0.14
melanoma NRAS_Q61K APC 52 99 Metastasis -0.10 -0.85 0.66 192.88 1.02 562 44 91 8 TRUE 0.11
melanoma NRAS_Q61K APC 10 27 Primary -0.75 -3.66 0.66 701.79 1.01 214 10 27 0 TRUE 0.27
melanoma NRAS_Q61K APC 62 126 Tumor Type:overall -0.40 -2.53 1.02 1312.10 1.00 776 54 118 8 TRUE 0.18
melanoma NRAS_Q61K ARID2 52 107 Metastasis 0.48 -0.20 1.08 1261.60 1.00 545 40 95 12 FALSE 0.85
melanoma NRAS_Q61K ARID2 10 43 Primary 0.30 -0.88 1.29 1550.26 1.00 214 8 41 2 FALSE 0.24
melanoma NRAS_Q61K ARID2 62 150 Tumor Type:overall 0.40 -0.74 1.51 1371.93 1.00 759 48 136 14 FALSE 0.31
melanoma NRAS_Q61K MTOR 50 40 Metastasis -1.02 -3.22 0.40 1254.06 1.00 581 49 39 1 TRUE 0.57
melanoma NRAS_Q61K MTOR 10 13 Primary -0.62 -2.84 1.42 1479.28 1.00 219 9 12 1 TRUE 0.26
melanoma NRAS_Q61K MTOR 60 53 Tumor Type:overall -0.80 -3.19 1.16 1386.55 1.00 800 58 51 2 TRUE 0.34
melanoma NRAS_Q61K NOTCH1 52 50 Metastasis -0.27 -1.50 0.72 1346.67 1.00 585 49 47 3 TRUE 0.20
melanoma NRAS_Q61K NOTCH1 10 17 Primary -0.14 -1.75 1.33 1123.80 1.00 224 9 16 1 TRUE 0.07
melanoma NRAS_Q61K NOTCH1 62 67 Tumor Type:overall -0.21 -1.83 1.18 1209.30 1.00 809 58 63 4 TRUE 0.11
melanoma NRAS_Q61K NTRK1 50 46 Metastasis -1.80 -4.60 0.08 1277.24 1.00 575 49 45 1 TRUE 0.88
melanoma NRAS_Q61K NTRK1 50 46 Tumor Type:overall -1.67 -6.11 2.96 1538.57 1.00 575 49 45 1 TRUE 0.35
melanoma NRAS_Q61K SETD2 50 77 Metastasis -0.69 -2.02 0.36 1331.85 1.00 557 47 74 3 FALSE 0.61
melanoma NRAS_Q61K SETD2 10 12 Primary -0.18 -2.19 1.70 1480.12 1.00 221 9 11 1 FALSE 0.07
melanoma NRAS_Q61K SETD2 60 89 Tumor Type:overall -0.42 -2.38 1.61 1370.83 1.00 778 56 85 4 FALSE 0.17
melanoma NRAS_Q61K PBRM1 50 55 Metastasis 0.00 -1.03 0.95 1098.67 1.00 574 45 50 5 TRUE 0.00
melanoma NRAS_Q61K PBRM1 10 19 Primary -0.65 -3.79 0.99 1098.66 1.00 216 10 19 0 TRUE 0.23
melanoma NRAS_Q61K PBRM1 60 74 Tumor Type:overall -0.31 -2.44 1.23 1110.86 1.00 790 55 69 5 TRUE 0.13
melanoma NRAS_Q61K EPHA3 50 87 Metastasis 0.07 -0.78 0.84 1380.34 1.00 556 43 80 7 FALSE 0.06
melanoma NRAS_Q61K EPHA3 10 20 Primary 0.01 -1.48 1.33 1544.01 1.00 215 9 19 1 FALSE 0.00
melanoma NRAS_Q61K EPHA3 60 107 Tumor Type:overall 0.05 -1.38 1.41 1566.23 1.00 771 52 99 8 FALSE 0.02
melanoma NRAS_Q61K KIT 52 43 Metastasis -1.99 -4.80 -0.16 1260.53 1.00 589 51 42 1 TRUE 1.02
melanoma NRAS_Q61K KIT 10 22 Primary -2.22 -5.67 -0.03 1281.79 1.00 214 10 22 0 TRUE 0.90
melanoma NRAS_Q61K KIT 62 65 Tumor Type:overall -2.08 -5.09 0.05 1333.08 1.00 803 61 64 1 TRUE 0.96
melanoma NRAS_Q61K KDR 52 103 Metastasis -1.49 -3.12 -0.30 1075.64 1.00 548 50 101 2 TRUE 1.53
melanoma NRAS_Q61K KDR 10 29 Primary -1.19 -2.94 0.50 942.79 1.00 212 9 28 1 TRUE 0.77
melanoma NRAS_Q61K KDR 62 132 Tumor Type:overall -1.30 -3.10 0.39 1383.83 1.00 760 59 129 3 TRUE 0.86
melanoma NRAS_Q61K CSF1R 52 41 Metastasis 0.31 -0.69 1.23 1235.54 1.00 597 47 36 5 TRUE 0.27
melanoma NRAS_Q61K CSF1R 10 16 Primary -0.42 -3.65 1.16 1070.59 1.00 220 10 16 0 TRUE 0.13
melanoma NRAS_Q61K CSF1R 62 57 Tumor Type:overall -0.04 -2.12 1.43 1212.61 1.00 817 57 52 5 TRUE 0.02
melanoma NRAS_Q61K PTCH1 50 43 Metastasis -1.70 -4.50 0.13 1434.43 1.00 578 49 42 1 TRUE 0.83
melanoma NRAS_Q61K PTCH1 50 43 Tumor Type:overall -1.40 -5.75 3.32 1434.80 1.00 578 49 42 1 TRUE 0.27
melanoma NRAS_Q61K TET1 50 48 Metastasis 0.00 -1.21 1.02 1184.66 1.00 580 46 44 4 FALSE 0.00
melanoma NRAS_Q61K TET1 50 48 Tumor Type:overall 0.00 -4.25 3.82 1502.85 1.00 580 46 44 4 FALSE 0.00
melanoma NRAS_Q61K FGFR2 52 59 Metastasis -1.36 -3.33 -0.04 1279.21 1.00 581 50 57 2 TRUE 0.98
melanoma NRAS_Q61K FGFR2 10 26 Primary -1.69 -4.79 0.14 1202.80 1.00 215 10 26 0 TRUE 0.79
melanoma NRAS_Q61K FGFR2 62 85 Tumor Type:overall -1.47 -3.84 0.22 1343.52 1.00 796 60 83 2 TRUE 0.81
melanoma NRAS_Q61K TBX3 50 47 Metastasis -0.86 -2.68 0.48 1523.01 1.00 578 48 45 2 FALSE 0.54
melanoma NRAS_Q61K TBX3 50 47 Tumor Type:overall -0.68 -5.07 3.93 1571.14 1.00 578 48 45 2 FALSE 0.12
melanoma NRAS_Q61K DICER1 50 44 Metastasis -2.22 -4.36 -0.28 10.58 1.11 579 49 43 1 TRUE 1.45
melanoma NRAS_Q61K DICER1 10 18 Primary -2.34 -5.22 -0.05 349.84 1.03 219 10 18 0 TRUE 1.20
melanoma NRAS_Q61K DICER1 60 62 Tumor Type:overall -2.26 -4.80 0.00 25.46 1.07 798 59 61 1 TRUE 1.34
melanoma NRAS_Q61K NTRK3 50 81 Metastasis -1.07 -2.56 0.05 1067.82 1.00 552 47 78 3 FALSE 0.99
melanoma NRAS_Q61K NTRK3 10 25 Primary -1.43 -3.94 0.19 1140.86 1.00 213 10 25 0 FALSE 0.71
melanoma NRAS_Q61K NTRK3 60 106 Tumor Type:overall -1.22 -3.16 0.34 1065.99 1.00 765 57 103 3 FALSE 0.75
melanoma NRAS_Q61K GRIN2A 51 221 Metastasis -0.67 -1.46 0.04 926.63 1.00 478 43 213 8 FALSE 1.08
melanoma NRAS_Q61K GRIN2A 12 80 Primary 0.28 -0.79 1.56 891.56 1.00 194 6 74 6 FALSE 0.18
melanoma NRAS_Q61K GRIN2A 63 301 Tumor Type:overall -0.20 -1.65 1.35 1611.58 1.00 672 49 287 14 FALSE 0.10
melanoma NRAS_Q61K BRD4 50 43 Metastasis 0.32 -0.73 1.20 1069.99 1.00 583 46 39 4 FALSE 0.29
melanoma NRAS_Q61K BRD4 10 19 Primary 0.56 -0.72 1.87 1439.88 1.00 216 8 17 2 FALSE 0.41
melanoma NRAS_Q61K BRD4 60 62 Tumor Type:overall 0.44 -1.02 1.79 1235.18 1.00 799 54 56 6 FALSE 0.28
melanoma NRAS_Q61K ASXL1 50 38 Metastasis 0.13 -1.04 1.15 667.61 1.00 585 46 34 4 TRUE 0.09
melanoma NRAS_Q61K ASXL1 10 13 Primary -0.40 -3.44 1.21 1172.80 1.00 219 10 13 0 TRUE 0.13
melanoma NRAS_Q61K ASXL1 60 51 Tumor Type:overall -0.11 -2.22 1.34 1080.58 1.00 804 56 47 4 TRUE 0.04
melanoma NRAS_Q61K EP300 50 46 Metastasis -2.50 -6.37 -0.28 1406.79 1.00 575 50 46 0 TRUE 0.95
melanoma NRAS_Q61K EP300 10 23 Primary -1.62 -4.52 0.94 1113.28 1.00 219 9 22 1 TRUE 0.61
melanoma NRAS_Q61K EP300 60 69 Tumor Type:overall -2.04 -5.45 0.42 1426.64 1.00 794 59 68 1 TRUE 0.78
melanoma NRAS_Q61K ERBB4 52 152 Metastasis -1.15 -2.19 -0.27 1276.88 1.00 521 47 147 5 TRUE 1.75
melanoma NRAS_Q61K ERBB4 10 41 Primary -1.68 -4.58 -0.18 1408.01 1.00 207 10 41 0 TRUE 0.91
melanoma NRAS_Q61K ERBB4 62 193 Tumor Type:overall -1.37 -3.29 0.15 1354.90 1.00 728 57 188 5 TRUE 0.91
melanoma NRAS_Q61K MDC1 50 73 Metastasis -0.46 -1.63 0.53 1224.88 1.00 561 46 69 4 FALSE 0.40
melanoma NRAS_Q61K MDC1 50 73 Tumor Type:overall -0.33 -4.08 4.25 1563.69 1.00 561 46 69 4 FALSE 0.06
melanoma NRAS_Q61K GNAQ 52 43 Metastasis -0.97 -2.77 0.50 952.03 1.00 587 50 41 2 TRUE 0.61
melanoma NRAS_Q61K GNAQ 10 16 Primary -1.29 -4.30 0.61 1117.76 1.00 218 10 16 0 TRUE 0.50
melanoma NRAS_Q61K GNAQ 62 59 Tumor Type:overall -1.09 -3.33 0.79 990.38 1.00 805 60 57 2 TRUE 0.52
melanoma NRAS_Q61K MED12 50 44 Metastasis -0.79 -2.68 0.57 1294.26 1.00 583 48 42 2 TRUE 0.47
melanoma NRAS_Q61K MED12 50 44 Tumor Type:overall -0.65 -4.87 4.12 1464.32 1.00 583 48 42 2 TRUE 0.12
melanoma NRAS_Q61K NF1 50 230 Metastasis -2.81 -4.60 -1.47 1371.83 1.00 462 48 228 2 TRUE 3.24
melanoma NRAS_Q61K NF1 10 67 Primary -3.12 -5.81 -1.29 1487.01 1.00 186 10 67 0 TRUE 1.87
melanoma NRAS_Q61K NF1 60 297 Tumor Type:overall -2.88 -5.03 -1.18 1402.96 1.00 648 58 295 2 TRUE 2.40
melanoma NRAS_Q61K FLT1 50 96 Metastasis -1.22 -2.69 -0.11 1251.40 1.00 540 47 93 3 FALSE 1.22
melanoma NRAS_Q61K FLT1 10 26 Primary -1.69 -4.95 0.10 1256.11 1.00 214 10 26 0 FALSE 0.75
melanoma NRAS_Q61K FLT1 60 122 Tumor Type:overall -1.43 -3.73 0.41 1316.74 1.00 754 57 119 3 FALSE 0.76
melanoma NRAS_Q61K RPTOR 50 37 Metastasis 0.03 -1.17 1.03 735.74 1.01 583 47 34 3 FALSE 0.02
melanoma NRAS_Q61K RPTOR 10 14 Primary 0.08 -1.53 1.48 1108.13 1.00 218 9 13 1 FALSE 0.04
melanoma NRAS_Q61K RPTOR 60 51 Tumor Type:overall 0.03 -1.49 1.39 1068.72 1.00 801 56 47 4 FALSE 0.01
melanoma NRAS_Q61K SF3B1 50 53 Metastasis -2.31 -5.12 -0.40 1447.86 1.00 564 49 52 1 TRUE 1.28
melanoma NRAS_Q61K SF3B1 10 39 Primary -2.72 -6.42 -0.40 1485.57 1.00 191 10 39 0 TRUE 1.11
melanoma NRAS_Q61K SF3B1 60 92 Tumor Type:overall -2.44 -5.50 -0.17 1569.00 1.00 755 59 91 1 TRUE 1.16
melanoma NRAS_Q61K ROS1 50 199 Metastasis -1.11 -2.00 -0.28 1291.94 1.00 486 44 193 6 TRUE 1.91
melanoma NRAS_Q61K ROS1 10 55 Primary -1.14 -2.62 0.08 1476.16 1.00 201 9 54 1 TRUE 0.99
melanoma NRAS_Q61K ROS1 60 254 Tumor Type:overall -1.12 -2.65 0.38 1576.55 1.00 687 53 247 7 TRUE 0.82
melanoma NRAS_Q61K FLT3 52 66 Metastasis -0.15 -1.26 0.76 1388.91 1.00 570 48 62 4 TRUE 0.11
melanoma NRAS_Q61K FLT3 10 14 Primary 0.60 -0.95 2.24 1460.42 1.00 224 8 12 2 TRUE 0.34
melanoma NRAS_Q61K FLT3 62 80 Tumor Type:overall 0.23 -1.41 2.13 1583.44 1.00 794 56 74 6 TRUE 0.10
melanoma NRAS_Q61K AXL 51 49 Metastasis 0.32 -0.64 1.23 1314.67 1.00 578 46 44 5 FALSE 0.30
melanoma NRAS_Q61K AXL 10 14 Primary 0.32 -1.16 1.64 1233.44 1.00 218 9 13 1 FALSE 0.18
melanoma NRAS_Q61K AXL 61 63 Tumor Type:overall 0.31 -1.03 1.61 1250.99 1.00 796 55 57 6 FALSE 0.19
melanoma NRAS_Q61K PIK3CG 50 81 Metastasis -1.69 -3.20 -0.32 335.25 1.02 556 48 79 2 FALSE 1.67
melanoma NRAS_Q61K PIK3CG 10 25 Primary -1.88 -4.20 -0.15 1025.33 1.00 213 10 25 0 FALSE 1.18
melanoma NRAS_Q61K PIK3CG 60 106 Tumor Type:overall -1.76 -3.72 -0.07 909.90 1.00 769 58 104 2 FALSE 1.19
melanoma NRAS_Q61K EGFR 52 54 Metastasis -0.30 -1.44 0.74 296.23 1.03 585 48 50 4 TRUE 0.23
melanoma NRAS_Q61K EGFR 10 13 Primary -0.72 -3.42 0.99 1107.73 1.00 221 10 13 0 TRUE 0.26
melanoma NRAS_Q61K EGFR 62 67 Tumor Type:overall -0.48 -2.60 1.08 1424.45 1.00 806 58 63 4 TRUE 0.22
melanoma NRAS_Q61K ARID1B 50 55 Metastasis -2.10 -4.95 -0.32 1155.10 1.00 569 49 54 1 TRUE 1.15
melanoma NRAS_Q61K ARID1B 10 20 Primary -2.28 -5.45 -0.10 1265.72 1.00 220 10 20 0 TRUE 0.97
melanoma NRAS_Q61K ARID1B 60 75 Tumor Type:overall -2.16 -5.15 -0.06 1341.35 1.00 789 59 74 1 TRUE 0.99
melanoma NRAS_Q61K GNA11 52 34 Metastasis -5.19 -12.15 -0.90 1192.19 1.00 594 52 34 0 TRUE 1.09
melanoma NRAS_Q61K GNA11 10 20 Primary -5.12 -12.51 -0.78 1216.46 1.00 214 10 20 0 TRUE 1.06
melanoma NRAS_Q61K GNA11 62 54 Tumor Type:overall -5.01 -11.97 -0.81 1154.98 1.00 808 62 54 0 TRUE 1.07
melanoma NRAS_Q61K INSR 50 54 Metastasis -0.59 -2.05 0.54 1440.84 1.00 579 47 51 3 FALSE 0.44
melanoma NRAS_Q61K INSR 10 13 Primary -0.97 -4.02 0.81 1338.92 1.00 217 10 13 0 FALSE 0.37
melanoma NRAS_Q61K INSR 60 67 Tumor Type:overall -0.75 -2.83 0.91 1466.58 1.00 796 57 64 3 FALSE 0.35
melanoma NRAS_Q61K ERG 50 39 Metastasis -0.29 -1.65 0.82 1386.48 1.00 585 47 36 3 FALSE 0.18
melanoma NRAS_Q61K ERG 10 14 Primary -0.74 -3.53 0.86 1298.19 1.00 219 10 14 0 FALSE 0.26
melanoma NRAS_Q61K ERG 60 53 Tumor Type:overall -0.52 -2.76 0.96 1294.50 1.00 804 57 50 3 FALSE 0.24
melanoma NRAS_Q61K MET 52 63 Metastasis -0.47 -1.18 0.58 4.20 1.23 574 48 59 4 TRUE 0.47
melanoma NRAS_Q61K MET 10 22 Primary -0.48 -1.47 0.96 5.95 1.16 216 9 21 1 TRUE 0.35
melanoma NRAS_Q61K MET 62 85 Tumor Type:overall -0.46 -1.37 1.03 6.06 1.16 790 57 80 5 TRUE 0.33
melanoma NRAS_Q61K BRAF 55 245 Metastasis -1.18 -1.97 -0.46 1408.23 1.00 407 46 236 9 TRUE 2.74
melanoma NRAS_Q61K BRAF 10 54 Primary -2.14 -6.04 -0.26 1255.96 1.00 182 10 54 0 TRUE 0.84
melanoma NRAS_Q61K BRAF 65 299 Tumor Type:overall -1.56 -3.87 0.19 1154.92 1.00 589 56 290 9 TRUE 0.92
melanoma NRAS_Q61K TET2 50 67 Metastasis -0.97 -2.40 0.07 959.80 1.00 559 48 65 2 TRUE 0.89
melanoma NRAS_Q61K TET2 10 25 Primary -0.81 -2.53 0.76 1270.32 1.00 213 9 24 1 TRUE 0.49
melanoma NRAS_Q61K TET2 60 92 Tumor Type:overall -0.89 -2.61 0.53 1184.68 1.00 772 57 89 3 TRUE 0.56
melanoma NRAS_Q61K PDGFRB 50 55 Metastasis -0.57 -1.92 0.52 1357.90 1.00 578 47 52 3 TRUE 0.44
melanoma NRAS_Q61K PDGFRB 10 11 Primary -1.00 -4.27 0.95 1008.27 1.00 221 10 11 0 TRUE 0.35
melanoma NRAS_Q61K PDGFRB 60 66 Tumor Type:overall -0.76 -2.98 1.06 1500.26 1.00 799 57 63 3 TRUE 0.34
melanoma NRAS_Q61K CARD11 51 91 Metastasis -0.37 -1.32 0.50 1303.52 1.00 546 46 86 5 FALSE 0.37
melanoma NRAS_Q61K CARD11 10 21 Primary -0.27 -1.78 1.21 1580.98 1.00 215 9 20 1 FALSE 0.14
melanoma NRAS_Q61K CARD11 61 112 Tumor Type:overall -0.33 -1.81 1.10 1498.54 1.00 761 55 106 6 FALSE 0.18
melanoma NRAS_Q61K CBL 50 64 Metastasis -0.91 -2.35 0.28 1381.86 1.00 560 48 62 2 TRUE 0.77
melanoma NRAS_Q61K CBL 10 19 Primary -0.66 -2.36 0.95 1441.63 1.00 214 9 18 1 TRUE 0.36
melanoma NRAS_Q61K CBL 60 83 Tumor Type:overall -0.75 -2.37 0.91 1498.05 1.00 774 57 80 3 TRUE 0.44
melanoma NRAS_Q61K TP63 52 134 Metastasis 0.14 -0.57 0.79 1336.89 1.00 516 41 123 11 FALSE 0.17
melanoma NRAS_Q61K TP63 10 37 Primary 0.16 -0.94 1.24 1385.53 1.00 208 8 35 2 FALSE 0.11
melanoma NRAS_Q61K TP63 62 171 Tumor Type:overall 0.14 -1.11 1.25 1131.72 1.00 724 49 158 13 FALSE 0.08
melanoma NRAS_Q61K GLI1 47 57 Metastasis -0.56 -1.93 0.58 1069.36 1.00 534 44 54 3 FALSE 0.41
melanoma NRAS_Q61K GLI1 47 57 Tumor Type:overall -0.55 -4.67 3.66 1563.83 1.00 534 44 54 3 FALSE 0.11
melanoma NRAS_Q61K ZFHX3 47 83 Metastasis -2.85 -7.13 -0.73 1144.31 1.00 512 47 83 0 FALSE 1.11
melanoma NRAS_Q61K ZFHX3 10 62 Primary -1.12 -3.35 0.61 1534.32 1.00 199 8 60 2 FALSE 0.58
melanoma NRAS_Q61K ZFHX3 57 145 Tumor Type:overall -1.88 -4.74 0.52 1433.70 1.00 711 55 143 2 FALSE 0.78
melanoma NRAS_Q61K MGA 47 73 Metastasis 0.25 -0.55 1.00 1127.96 1.00 526 40 66 7 FALSE 0.27
melanoma NRAS_Q61K MGA 10 23 Primary 0.12 -1.22 1.23 1324.01 1.00 200 9 22 1 FALSE 0.07
melanoma NRAS_Q61K MGA 57 96 Tumor Type:overall 0.16 -1.32 1.26 1245.19 1.00 726 49 88 8 FALSE 0.10
melanoma NRAS_Q61K ANKRD11 47 57 Metastasis -1.24 -3.11 0.10 666.60 1.01 537 45 55 2 FALSE 0.95
melanoma NRAS_Q61K ANKRD11 10 19 Primary -1.50 -3.92 0.23 649.75 1.01 202 10 19 0 FALSE 0.77
melanoma NRAS_Q61K ANKRD11 57 76 Tumor Type:overall -1.35 -3.39 0.33 946.35 1.00 739 55 74 2 FALSE 0.81
melanoma NRAS_Q61K PGR 47 44 Metastasis -0.95 -2.73 0.42 952.77 1.00 543 45 42 2 FALSE 0.61
melanoma NRAS_Q61K PGR 10 12 Primary -1.26 -4.08 0.54 1074.43 1.00 205 10 12 0 FALSE 0.52
melanoma NRAS_Q61K PGR 57 56 Tumor Type:overall -1.06 -3.25 0.60 950.70 1.00 748 55 54 2 FALSE 0.52
melanoma NRAS_Q61K PLCG2 47 47 Metastasis -1.94 -4.75 -0.05 858.66 1.00 539 46 46 1 FALSE 1.02
melanoma NRAS_Q61K PLCG2 10 16 Primary -2.09 -5.37 0.27 1003.35 1.00 203 10 16 0 FALSE 0.89
melanoma NRAS_Q61K PLCG2 57 63 Tumor Type:overall -2.01 -4.92 0.07 1048.83 1.00 742 56 62 1 FALSE 0.92
melanoma NRAS_Q61K EPHA7 48 125 Metastasis 0.11 -0.66 0.80 511.92 1.00 495 37 114 11 FALSE 0.11
melanoma NRAS_Q61K EPHA7 10 34 Primary -0.91 -4.59 0.69 1039.04 1.00 193 10 34 0 FALSE 0.29
melanoma NRAS_Q61K EPHA7 58 159 Tumor Type:overall -0.40 -2.64 0.88 1232.70 1.00 688 47 148 11 FALSE 0.18
melanoma NRAS_Q61R SPEN 69 92 Metastasis -0.87 -1.93 -0.01 1541.45 1.00 534 65 88 4 FALSE 1.10
melanoma NRAS_Q61R SPEN 9 25 Primary 0.10 -1.64 1.86 1267.97 1.00 216 7 23 2 FALSE 0.04
melanoma NRAS_Q61R SPEN 78 117 Tumor Type:overall -0.41 -2.34 1.60 1428.22 1.00 750 72 111 6 FALSE 0.16
melanoma NRAS_Q61R KMT2C 70 122 Metastasis -0.41 -1.17 0.27 1533.66 1.00 508 61 113 9 FALSE 0.58
melanoma NRAS_Q61R KMT2C 9 27 Primary -0.38 -2.22 1.24 1532.42 1.00 213 8 26 1 FALSE 0.18
melanoma NRAS_Q61R KMT2C 79 149 Tumor Type:overall -0.37 -2.21 1.56 1453.60 1.00 721 69 139 10 FALSE 0.16
melanoma NRAS_Q61R TP53 70 162 Metastasis -0.50 -1.19 0.13 1496.40 1.00 478 58 150 12 TRUE 0.87
melanoma NRAS_Q61R TP53 9 48 Primary -1.73 -5.87 0.11 1359.24 1.00 196 9 48 0 TRUE 0.56
thyroid cancer NRAS_Q61R TP53 32 32 Metastasis 0.16 -0.72 1.00 699.53 1.01 202 27 27 5 TRUE 0.14
thyroid cancer NRAS_Q61R TP53 32 45 Primary 0.14 -0.73 0.90 1096.43 1.00 147 25 38 7 TRUE 0.13
melanoma NRAS_Q61R TP53 79 210 Tumor Type:overall -1.06 -3.76 0.77 1356.17 1.00 674 67 198 12 TRUE 0.47
thyroid cancer NRAS_Q61R TP53 64 77 Tumor Type:overall 0.15 -0.92 1.27 1289.28 1.00 349 52 65 12 TRUE 0.10
melanoma NRAS_Q61R ATRX 70 78 Metastasis -0.61 -1.64 0.22 1345.17 1.00 542 65 73 5 TRUE 0.69
melanoma NRAS_Q61R ATRX 9 30 Primary -0.52 -2.08 0.97 1347.44 1.00 211 8 29 1 TRUE 0.29
melanoma NRAS_Q61R ATRX 79 108 Tumor Type:overall -0.56 -2.21 1.11 1274.79 1.00 753 73 102 6 TRUE 0.31
melanoma NRAS_Q61R ATR 69 49 Metastasis -0.48 -1.77 0.51 1310.74 1.00 553 66 46 3 FALSE 0.39
melanoma NRAS_Q61R ATR 10 16 Primary 0.49 -1.34 2.21 1387.24 1.00 219 8 14 2 FALSE 0.24
melanoma NRAS_Q61R ATR 79 65 Tumor Type:overall 0.02 -1.84 2.04 1505.28 1.00 772 74 60 5 FALSE 0.01
melanoma NRAS_Q61R PDGFRA 70 66 Metastasis -2.59 -5.22 -0.84 1555.68 1.00 556 69 65 1 TRUE 1.65
melanoma NRAS_Q61R PDGFRA 9 12 Primary -2.79 -6.96 0.17 1462.10 1.00 225 9 12 0 TRUE 0.90
melanoma NRAS_Q61R PDGFRA 79 78 Tumor Type:overall -2.60 -5.71 0.08 1543.37 1.00 781 78 77 1 TRUE 1.12
melanoma NRAS_Q61R NSD1 69 45 Metastasis -0.44 -1.65 0.56 1543.09 1.00 559 66 42 3 FALSE 0.36
melanoma NRAS_Q61R NSD1 9 12 Primary 0.02 -2.00 1.86 1339.63 1.00 220 8 11 1 FALSE 0.01
melanoma NRAS_Q61R NSD1 78 57 Tumor Type:overall -0.22 -2.31 1.62 1207.08 1.00 779 74 53 4 FALSE 0.08
melanoma NRAS_Q61R FLT4 69 74 Metastasis 0.04 -0.74 0.76 1284.14 1.00 540 61 66 8 TRUE 0.04
melanoma NRAS_Q61R FLT4 9 19 Primary 0.02 -1.86 1.50 1601.69 1.00 218 8 18 1 TRUE 0.01
melanoma NRAS_Q61R FLT4 78 93 Tumor Type:overall 0.04 -1.65 1.80 1466.87 1.00 758 69 84 9 TRUE 0.01
melanoma NRAS_Q61R PTPRD 73 204 Metastasis -0.34 -0.95 0.25 1230.09 1.00 479 58 189 15 FALSE 0.54
melanoma NRAS_Q61R PTPRD 13 69 Primary 1.15 -0.04 2.44 1424.47 1.00 191 5 61 8 FALSE 1.16
melanoma NRAS_Q61R PTPRD 86 273 Tumor Type:overall 0.40 -1.62 2.62 1474.53 1.00 670 63 250 23 FALSE 0.15
melanoma NRAS_Q61R RET 70 42 Metastasis -1.54 -3.66 0.03 1614.05 1.00 570 69 41 1 TRUE 1.01
melanoma NRAS_Q61R RET 9 22 Primary -0.90 -3.34 1.16 1501.10 1.00 222 8 21 1 TRUE 0.37
melanoma NRAS_Q61R RET 79 64 Tumor Type:overall -1.21 -3.43 0.95 1448.07 1.00 792 77 62 2 TRUE 0.54
melanoma NRAS_Q61R PIK3C2G 70 150 Metastasis 0.00 -0.64 0.60 1601.64 1.00 503 56 136 14 FALSE 0.00
melanoma NRAS_Q61R PIK3C2G 10 46 Primary 0.67 -0.52 1.97 1390.79 1.00 206 6 42 4 FALSE 0.54
melanoma NRAS_Q61R PIK3C2G 80 196 Tumor Type:overall 0.32 -1.19 1.99 1555.94 1.00 709 62 178 18 FALSE 0.16
melanoma NRAS_Q61R CREBBP 69 55 Metastasis -0.41 -1.49 0.52 1439.75 1.00 553 65 51 4 TRUE 0.37
melanoma NRAS_Q61R CREBBP 9 17 Primary -0.14 -2.02 1.55 1536.21 1.00 218 8 16 1 TRUE 0.06
melanoma NRAS_Q61R CREBBP 78 72 Tumor Type:overall -0.32 -2.17 1.41 1386.60 1.00 771 73 67 5 TRUE 0.14
melanoma NRAS_Q61R DOT1L 69 42 Metastasis -0.29 -1.50 0.68 1472.48 1.00 561 66 39 3 FALSE 0.22
melanoma NRAS_Q61R DOT1L 9 15 Primary 0.72 -1.09 2.42 1512.40 1.00 221 7 13 2 FALSE 0.38
melanoma NRAS_Q61R DOT1L 78 57 Tumor Type:overall 0.19 -1.81 2.27 1522.25 1.00 782 73 52 5 FALSE 0.07
melanoma NRAS_Q61R PTPRS 69 55 Metastasis -0.26 -1.34 0.61 1395.16 1.00 551 64 50 5 FALSE 0.22
melanoma NRAS_Q61R PTPRS 9 12 Primary -1.01 -4.82 1.00 1452.66 1.00 221 9 12 0 FALSE 0.29
melanoma NRAS_Q61R PTPRS 78 67 Tumor Type:overall -0.58 -3.14 1.29 1588.93 1.00 772 73 62 5 FALSE 0.21
melanoma NRAS_Q61R SMARCA4 69 54 Metastasis 0.25 -0.66 0.96 1549.09 1.00 552 62 47 7 FALSE 0.26
melanoma NRAS_Q61R SMARCA4 9 18 Primary 0.17 -1.42 1.58 1638.53 1.00 218 8 17 1 FALSE 0.08
melanoma NRAS_Q61R SMARCA4 78 72 Tumor Type:overall 0.20 -1.51 1.57 1652.51 1.00 770 70 64 8 FALSE 0.10
melanoma NRAS_Q61R PTPRT 73 290 Metastasis -0.21 -0.74 0.28 1393.32 1.00 436 50 267 23 FALSE 0.38
melanoma NRAS_Q61R PTPRT 12 82 Primary 0.44 -0.51 1.54 1476.83 1.00 191 6 76 6 FALSE 0.38
melanoma NRAS_Q61R PTPRT 85 372 Tumor Type:overall 0.13 -1.34 1.98 1429.66 1.00 627 56 343 29 FALSE 0.06
melanoma NRAS_Q61R HGF 69 62 Metastasis -0.75 -1.94 0.25 1371.64 1.00 547 65 58 4 FALSE 0.74
melanoma NRAS_Q61R HGF 9 21 Primary -1.36 -4.87 0.62 1451.14 1.00 214 9 21 0 FALSE 0.50
melanoma NRAS_Q61R HGF 78 83 Tumor Type:overall -1.02 -3.34 0.84 1427.33 1.00 761 74 79 4 FALSE 0.50
melanoma NRAS_Q61R ALK 70 108 Metastasis 0.08 -0.58 0.71 1459.48 1.00 536 58 96 12 TRUE 0.10
melanoma NRAS_Q61R ALK 9 20 Primary -1.09 -5.25 0.84 1350.29 1.00 218 9 20 0 TRUE 0.32
melanoma NRAS_Q61R ALK 79 128 Tumor Type:overall -0.42 -3.13 1.64 1581.11 1.00 754 67 116 12 TRUE 0.14
melanoma NRAS_Q61R BAP1 69 45 Metastasis -2.19 -4.72 -0.47 407.21 1.01 554 68 44 1 TRUE 1.28
melanoma NRAS_Q61R BAP1 9 21 Primary -2.46 -6.10 0.05 371.44 1.01 211 9 21 0 TRUE 0.88
melanoma NRAS_Q61R BAP1 78 66 Tumor Type:overall -2.27 -5.30 0.16 580.91 1.00 765 77 65 1 TRUE 0.98
melanoma NRAS_Q61R PTEN 70 64 Metastasis -0.26 -1.24 0.63 1503.15 1.00 551 65 59 5 TRUE 0.23
melanoma NRAS_Q61R PTEN 9 15 Primary 0.70 -0.97 2.32 1557.47 1.00 222 7 13 2 TRUE 0.38
melanoma NRAS_Q61R PTEN 79 79 Tumor Type:overall 0.24 -1.53 2.41 1658.94 1.00 773 72 72 7 TRUE 0.09
melanoma NRAS_Q61R CTNNB1 70 48 Metastasis -0.09 -1.16 0.83 1409.26 1.00 566 65 43 5 TRUE 0.07
melanoma NRAS_Q61R CTNNB1 70 48 Tumor Type:overall -0.06 -4.29 4.56 1516.71 1.00 566 65 43 5 TRUE 0.01
melanoma NRAS_Q61R ARID1A 69 76 Metastasis -0.77 -1.88 0.10 1254.86 1.00 535 65 72 4 TRUE 0.85
melanoma NRAS_Q61R ARID1A 9 13 Primary -0.17 -2.13 1.81 1336.67 1.00 220 8 12 1 TRUE 0.06
melanoma NRAS_Q61R ARID1A 78 89 Tumor Type:overall -0.47 -2.63 1.56 1489.79 1.00 755 73 84 5 TRUE 0.19
melanoma NRAS_Q61R IKZF1 69 87 Metastasis -1.97 -3.81 -0.66 1571.59 1.00 529 67 85 2 TRUE 1.94
melanoma NRAS_Q61R IKZF1 9 22 Primary -2.31 -5.47 0.07 1388.73 1.00 219 9 22 0 TRUE 0.96
melanoma NRAS_Q61R IKZF1 78 109 Tumor Type:overall -2.08 -4.66 0.21 1358.84 1.00 748 76 107 2 TRUE 1.06
melanoma NRAS_Q61R TERT 73 509 Metastasis 0.92 0.33 1.56 1439.02 1.00 233 14 450 59 TRUE 2.48
melanoma NRAS_Q61R TERT 14 105 Primary 1.86 0.70 3.36 1410.67 1.00 155 2 93 12 TRUE 2.29
thyroid cancer NRAS_Q61R TERT 31 142 Metastasis 0.54 -0.09 1.16 662.63 1.00 97 9 120 22 TRUE 1.01
thyroid cancer NRAS_Q61R TERT 26 114 Primary 0.50 -0.17 1.11 656.52 1.00 70 9 97 17 TRUE 0.87
melanoma NRAS_Q61R TERT 87 614 Tumor Type:overall 1.33 -0.57 3.49 1405.18 1.00 388 16 543 71 TRUE 0.76
thyroid cancer NRAS_Q61R TERT 57 256 Tumor Type:overall 0.51 -0.18 1.20 868.50 1.00 167 18 217 39 TRUE 0.71
melanoma NRAS_Q61R FAT1 70 121 Metastasis -0.32 -1.09 0.35 1414.49 1.00 506 61 112 9 FALSE 0.41
melanoma NRAS_Q61R FAT1 10 28 Primary 1.21 -0.25 2.57 1091.74 1.00 216 6 24 4 FALSE 1.03
melanoma NRAS_Q61R FAT1 80 149 Tumor Type:overall 0.44 -1.59 2.63 1499.65 1.00 722 67 136 13 FALSE 0.17
melanoma NRAS_Q61R CIC 69 38 Metastasis -2.09 -4.88 -0.22 1328.80 1.00 563 68 37 1 TRUE 1.11
melanoma NRAS_Q61R CIC 9 16 Primary -2.41 -6.51 0.18 1405.74 1.00 216 9 16 0 TRUE 0.73
melanoma NRAS_Q61R CIC 78 54 Tumor Type:overall -2.17 -5.37 0.32 1433.43 1.00 779 77 53 1 TRUE 0.84
melanoma NRAS_Q61R KDM6A 69 22 Metastasis -0.66 -2.50 0.79 1530.64 1.00 579 67 20 2 FALSE 0.35
melanoma NRAS_Q61R KDM6A 9 49 Primary -2.50 -7.31 0.09 1497.48 1.00 224 9 49 0 FALSE 0.68
melanoma NRAS_Q61R KDM6A 78 71 Tumor Type:overall -1.44 -4.99 1.28 1413.53 1.00 803 76 69 2 FALSE 0.43
melanoma NRAS_Q61R POLE 69 58 Metastasis -0.01 -0.94 0.78 1590.07 1.00 548 63 52 6 TRUE 0.00
melanoma NRAS_Q61R POLE 9 14 Primary 0.12 -1.84 1.69 1413.83 1.00 220 8 13 1 TRUE 0.05
melanoma NRAS_Q61R POLE 78 72 Tumor Type:overall 0.04 -1.92 1.72 1471.11 1.00 768 71 65 7 TRUE 0.01
melanoma NRAS_Q61R NOTCH2 69 56 Metastasis -2.32 -4.97 -0.43 1297.97 1.00 550 68 55 1 TRUE 1.29
melanoma NRAS_Q61R NOTCH2 69 56 Tumor Type:overall -2.02 -6.38 3.03 1445.26 1.00 550 68 55 1 TRUE 0.43
melanoma NRAS_Q61R KMT2A 70 104 Metastasis 0.10 -0.59 0.75 401.66 1.00 529 58 92 12 FALSE 0.11
melanoma NRAS_Q61R KMT2A 9 36 Primary -0.24 -1.95 1.05 1385.85 1.00 210 8 35 1 FALSE 0.13
melanoma NRAS_Q61R KMT2A 79 140 Tumor Type:overall -0.05 -1.68 1.49 1487.96 1.00 739 66 127 13 FALSE 0.02
melanoma NRAS_Q61R PAK7 71 174 Metastasis -0.34 -1.02 0.24 1385.31 1.00 474 58 161 13 FALSE 0.54
melanoma NRAS_Q61R PAK7 9 44 Primary 0.86 -0.52 2.25 1432.35 1.00 208 5 40 4 FALSE 0.65
melanoma NRAS_Q61R PAK7 80 218 Tumor Type:overall 0.22 -1.66 2.37 1442.15 1.00 682 63 201 17 FALSE 0.09
melanoma NRAS_Q61R BRCA2 70 70 Metastasis -0.45 -1.47 0.42 1532.68 1.00 544 65 65 5 TRUE 0.47
melanoma NRAS_Q61R BRCA2 9 22 Primary -0.31 -2.18 1.27 1593.43 1.00 217 8 21 1 TRUE 0.14
melanoma NRAS_Q61R BRCA2 79 92 Tumor Type:overall -0.41 -2.32 1.21 1444.72 1.00 761 73 86 6 TRUE 0.19
melanoma NRAS_Q61R NOTCH3 69 98 Metastasis -1.28 -2.43 -0.33 1451.94 1.00 522 65 94 4 TRUE 1.72
melanoma NRAS_Q61R NOTCH3 9 32 Primary -1.91 -5.43 -0.02 1316.59 1.00 210 9 32 0 TRUE 0.78
melanoma NRAS_Q61R NOTCH3 78 130 Tumor Type:overall -1.54 -3.80 0.32 1587.28 1.00 732 74 126 4 TRUE 0.85
melanoma NRAS_Q61R NOTCH4 70 115 Metastasis -0.22 -0.95 0.45 1360.20 1.00 519 60 105 10 TRUE 0.27
melanoma NRAS_Q61R NOTCH4 9 33 Primary -0.40 -2.02 0.93 1279.98 1.00 207 8 32 1 TRUE 0.23
melanoma NRAS_Q61R NOTCH4 79 148 Tumor Type:overall -0.28 -1.91 1.40 1590.78 1.00 726 68 137 11 TRUE 0.14
melanoma NRAS_Q61R CDKN2A 70 112 Metastasis -1.16 -2.28 -0.23 1386.66 1.00 514 66 108 4 TRUE 1.57
melanoma NRAS_Q61R CDKN2A 9 17 Primary 0.54 -1.50 2.42 1537.39 1.00 221 7 15 2 TRUE 0.23
melanoma NRAS_Q61R CDKN2A 79 129 Tumor Type:overall -0.25 -2.56 2.33 1399.92 1.00 735 73 123 6 TRUE 0.08
melanoma NRAS_Q61R EPHB1 69 45 Metastasis -0.09 -1.20 0.84 1462.29 1.00 561 65 41 4 FALSE 0.07
melanoma NRAS_Q61R EPHB1 9 21 Primary 0.46 -1.03 2.05 1491.13 1.00 213 7 19 2 FALSE 0.26
melanoma NRAS_Q61R EPHB1 78 66 Tumor Type:overall 0.18 -1.59 1.92 1509.77 1.00 774 72 60 6 FALSE 0.08
melanoma NRAS_Q61R IL7R 69 73 Metastasis -0.48 -1.47 0.36 1430.86 1.00 541 64 68 5 FALSE 0.49
melanoma NRAS_Q61R IL7R 9 21 Primary -0.30 -2.05 1.30 1425.86 1.00 217 8 20 1 FALSE 0.14
melanoma NRAS_Q61R IL7R 78 94 Tumor Type:overall -0.39 -2.22 1.36 1209.41 1.00 758 72 88 6 FALSE 0.18
melanoma NRAS_Q61R ATM 71 57 Metastasis -0.02 -0.93 0.80 1433.45 1.00 560 65 51 6 TRUE 0.02
melanoma NRAS_Q61R ATM 9 21 Primary -0.03 -1.71 1.48 1466.84 1.00 218 8 20 1 TRUE 0.01
melanoma NRAS_Q61R ATM 80 78 Tumor Type:overall -0.04 -1.76 1.68 1502.26 1.00 778 73 71 7 TRUE 0.02
melanoma NRAS_Q61R MAP2K1 69 50 Metastasis -1.28 -3.08 0.18 849.06 1.00 551 67 48 2 TRUE 0.89
melanoma NRAS_Q61R MAP2K1 69 50 Tumor Type:overall -1.04 -5.27 3.94 1445.61 1.00 551 67 48 2 TRUE 0.20
melanoma NRAS_Q61R RB1 71 43 Metastasis 0.84 0.03 1.58 992.12 1.00 580 62 34 9 TRUE 1.48
melanoma NRAS_Q61R RB1 71 43 Tumor Type:overall 0.70 -4.14 5.43 1445.00 1.00 580 62 34 9 TRUE 0.13
melanoma NRAS_Q61R KMT2D 72 175 Metastasis -0.33 -0.96 0.30 1515.82 1.00 494 59 162 13 FALSE 0.53
melanoma NRAS_Q61R KMT2D 11 43 Primary 0.56 -0.64 1.85 1444.51 1.00 205 7 39 4 FALSE 0.41
melanoma NRAS_Q61R KMT2D 83 218 Tumor Type:overall 0.10 -1.50 1.94 1304.13 1.00 699 66 201 17 FALSE 0.04
melanoma NRAS_Q61R APC 71 99 Metastasis -1.09 -2.19 -0.20 1327.62 1.00 539 67 95 4 TRUE 1.55
melanoma NRAS_Q61R APC 9 27 Primary -0.80 -2.67 0.99 1420.97 1.00 216 8 26 1 TRUE 0.43
melanoma NRAS_Q61R APC 80 126 Tumor Type:overall -0.92 -2.67 0.88 1288.73 1.00 755 75 121 5 TRUE 0.53
melanoma NRAS_Q61R ARID2 72 107 Metastasis -0.31 -1.06 0.34 1443.85 1.00 521 64 99 8 FALSE 0.40
melanoma NRAS_Q61R ARID2 11 43 Primary 0.51 -0.66 1.75 1415.41 1.00 215 7 39 4 FALSE 0.39
melanoma NRAS_Q61R ARID2 83 150 Tumor Type:overall 0.11 -1.43 1.83 1532.21 1.00 736 71 138 12 FALSE 0.05
melanoma NRAS_Q61R MTOR 69 40 Metastasis -0.24 -1.45 0.72 536.81 1.00 565 65 36 4 TRUE 0.17
melanoma NRAS_Q61R MTOR 9 13 Primary -0.94 -4.54 0.99 831.58 1.00 219 9 13 0 TRUE 0.28
melanoma NRAS_Q61R MTOR 78 53 Tumor Type:overall -0.58 -3.25 1.13 867.10 1.00 784 74 49 4 TRUE 0.21
melanoma NRAS_Q61R NOTCH1 70 50 Metastasis -1.60 -3.74 -0.23 1496.43 1.00 565 69 49 1 TRUE 1.11
melanoma NRAS_Q61R NOTCH1 9 17 Primary -0.82 -3.16 1.32 1495.15 1.00 225 8 16 1 TRUE 0.32
melanoma NRAS_Q61R NOTCH1 79 67 Tumor Type:overall -1.21 -3.73 1.07 1488.23 1.00 790 77 65 2 TRUE 0.51
melanoma NRAS_Q61R NTRK1 69 46 Metastasis -0.67 -2.09 0.47 1456.60 1.00 558 66 43 3 TRUE 0.53
melanoma NRAS_Q61R NTRK1 69 46 Tumor Type:overall -0.52 -4.61 4.10 1287.93 1.00 558 66 43 3 TRUE 0.10
melanoma NRAS_Q61R SETD2 69 77 Metastasis -0.34 -1.27 0.47 1489.86 1.00 541 63 71 6 FALSE 0.34
melanoma NRAS_Q61R SETD2 9 12 Primary 0.10 -2.02 1.93 1365.41 1.00 222 8 11 1 FALSE 0.04
melanoma NRAS_Q61R SETD2 78 89 Tumor Type:overall -0.10 -2.01 1.90 1438.28 1.00 763 71 82 7 FALSE 0.04
melanoma NRAS_Q61R PBRM1 69 55 Metastasis -0.74 -1.91 0.28 1433.17 1.00 553 66 52 3 TRUE 0.69
melanoma NRAS_Q61R PBRM1 9 19 Primary -0.41 -2.33 1.29 1481.97 1.00 218 8 18 1 TRUE 0.18
melanoma NRAS_Q61R PBRM1 78 74 Tumor Type:overall -0.55 -2.41 1.30 1498.79 1.00 771 74 70 4 TRUE 0.25
melanoma NRAS_Q61R EPHA3 70 87 Metastasis 0.06 -0.71 0.76 1261.84 1.00 539 60 77 10 FALSE 0.06
melanoma NRAS_Q61R EPHA3 9 20 Primary -1.01 -4.62 0.94 1464.39 1.00 215 9 20 0 FALSE 0.31
melanoma NRAS_Q61R EPHA3 79 107 Tumor Type:overall -0.47 -3.33 1.54 1402.55 1.00 754 69 97 10 FALSE 0.16
melanoma NRAS_Q61R KIT 70 43 Metastasis -2.18 -4.84 -0.26 1366.74 1.00 571 69 42 1 TRUE 1.20
melanoma NRAS_Q61R KIT 9 22 Primary -2.52 -6.26 0.12 1303.96 1.00 215 9 22 0 TRUE 0.83
melanoma NRAS_Q61R KIT 79 65 Tumor Type:overall -2.29 -5.45 0.19 1342.19 1.00 786 78 64 1 TRUE 0.90
melanoma NRAS_Q61R KDR 70 103 Metastasis -0.59 -1.48 0.21 1367.85 1.00 534 64 97 6 TRUE 0.73
melanoma NRAS_Q61R KDR 10 29 Primary 2.21 0.75 3.65 1327.67 1.00 217 4 23 6 TRUE 2.70
melanoma NRAS_Q61R KDR 80 132 Tumor Type:overall 0.73 -2.15 3.43 1379.96 1.00 751 68 120 12 TRUE 0.23
melanoma NRAS_Q61R CSF1R 70 41 Metastasis -0.69 -2.14 0.47 1472.90 1.00 577 67 38 3 TRUE 0.52
melanoma NRAS_Q61R CSF1R 9 16 Primary -1.29 -4.63 0.77 1444.01 1.00 221 9 16 0 TRUE 0.45
melanoma NRAS_Q61R CSF1R 79 57 Tumor Type:overall -0.95 -3.42 1.00 1587.42 1.00 798 76 54 3 TRUE 0.40
melanoma NRAS_Q61R PTCH1 69 43 Metastasis -1.10 -2.86 0.30 1132.31 1.00 560 67 41 2 TRUE 0.75
melanoma NRAS_Q61R PTCH1 69 43 Tumor Type:overall -0.92 -5.28 4.16 1408.42 1.00 560 67 41 2 TRUE 0.17
melanoma NRAS_Q61R TET1 69 48 Metastasis -0.39 -1.56 0.63 459.03 1.00 561 65 44 4 FALSE 0.30
melanoma NRAS_Q61R TET1 69 48 Tumor Type:overall -0.31 -4.44 4.53 1425.72 1.00 561 65 44 4 FALSE 0.05
melanoma NRAS_Q61R FGFR2 70 59 Metastasis -0.41 -1.45 0.47 1438.57 1.00 566 65 54 5 TRUE 0.39
melanoma NRAS_Q61R FGFR2 9 26 Primary -1.26 -5.01 0.55 1138.22 1.00 216 9 26 0 TRUE 0.41
melanoma NRAS_Q61R FGFR2 79 85 Tumor Type:overall -0.81 -3.40 1.04 1189.18 1.00 782 74 80 5 TRUE 0.33
melanoma NRAS_Q61R TBX3 69 47 Metastasis -2.14 -4.86 -0.30 1281.65 1.00 558 68 46 1 FALSE 1.16
melanoma NRAS_Q61R TBX3 69 47 Tumor Type:overall -1.83 -6.26 3.42 1425.79 1.00 558 68 46 1 FALSE 0.37
melanoma NRAS_Q61R DICER1 71 44 Metastasis 0.84 -0.04 1.56 551.04 1.01 566 62 35 9 TRUE 1.41
melanoma NRAS_Q61R DICER1 9 18 Primary 0.99 -0.47 2.30 799.97 1.00 222 7 16 2 TRUE 0.80
melanoma NRAS_Q61R DICER1 80 62 Tumor Type:overall 0.89 -0.65 2.51 861.32 1.00 788 69 51 11 TRUE 0.58
melanoma NRAS_Q61R NTRK3 70 81 Metastasis -0.35 -1.23 0.43 1422.74 1.00 536 63 74 7 FALSE 0.38
melanoma NRAS_Q61R NTRK3 9 25 Primary -1.31 -5.31 0.55 1416.48 1.00 214 9 25 0 FALSE 0.41
melanoma NRAS_Q61R NTRK3 79 106 Tumor Type:overall -0.77 -3.56 1.05 1412.99 1.00 750 72 99 7 FALSE 0.32
melanoma NRAS_Q61R GRIN2A 73 221 Metastasis -0.31 -0.88 0.23 1354.72 1.00 466 55 203 18 FALSE 0.58
melanoma NRAS_Q61R GRIN2A 10 80 Primary -0.55 -1.88 0.58 1385.12 1.00 192 8 78 2 FALSE 0.45
melanoma NRAS_Q61R GRIN2A 83 301 Tumor Type:overall -0.42 -1.88 0.92 1492.39 1.00 658 63 281 20 FALSE 0.26
melanoma NRAS_Q61R BRD4 69 43 Metastasis -0.89 -2.40 0.30 1565.89 1.00 562 67 41 2 FALSE 0.71
melanoma NRAS_Q61R BRD4 9 19 Primary -0.51 -2.48 1.30 1369.81 1.00 216 8 18 1 FALSE 0.23
melanoma NRAS_Q61R BRD4 78 62 Tumor Type:overall -0.68 -2.76 1.21 1566.32 1.00 778 75 59 3 FALSE 0.31
melanoma NRAS_Q61R ASXL1 69 38 Metastasis -2.01 -4.79 -0.17 1409.76 1.00 563 68 37 1 TRUE 1.06
melanoma NRAS_Q61R ASXL1 9 13 Primary -2.32 -6.58 0.29 1349.51 1.00 220 9 13 0 TRUE 0.71
melanoma NRAS_Q61R ASXL1 78 51 Tumor Type:overall -2.11 -5.47 0.32 1488.21 1.00 783 77 50 1 TRUE 0.79
melanoma NRAS_Q61R EP300 70 46 Metastasis -0.82 -2.22 0.26 1438.83 1.00 558 67 43 3 TRUE 0.69
melanoma NRAS_Q61R EP300 9 23 Primary -1.61 -5.08 0.45 1438.05 1.00 219 9 23 0 TRUE 0.59
melanoma NRAS_Q61R EP300 79 69 Tumor Type:overall -1.19 -3.74 0.82 1476.54 1.00 777 76 66 3 TRUE 0.54
melanoma NRAS_Q61R ERBB4 73 152 Metastasis -0.32 -1.04 0.29 1558.07 1.00 507 61 140 12 TRUE 0.48
melanoma NRAS_Q61R ERBB4 9 41 Primary -0.03 -1.38 1.36 1424.43 1.00 210 7 39 2 TRUE 0.02
melanoma NRAS_Q61R ERBB4 82 193 Tumor Type:overall -0.20 -1.95 1.47 1488.18 1.00 717 68 179 14 TRUE 0.09
melanoma NRAS_Q61R MDC1 69 73 Metastasis -0.57 -1.64 0.30 1305.98 1.00 543 64 68 5 FALSE 0.63
melanoma NRAS_Q61R MDC1 69 73 Tumor Type:overall -0.49 -4.49 3.50 1615.15 1.00 543 64 68 5 FALSE 0.10
melanoma NRAS_Q61R GNAQ 70 43 Metastasis -5.60 -12.63 -1.43 1359.41 1.00 567 70 43 0 TRUE 1.30
melanoma NRAS_Q61R GNAQ 9 16 Primary -5.45 -12.43 -0.94 1364.43 1.00 219 9 16 0 TRUE 1.16
melanoma NRAS_Q61R GNAQ 79 59 Tumor Type:overall -5.35 -12.16 -1.06 1406.79 1.00 786 79 59 0 TRUE 1.23
melanoma NRAS_Q61R MED12 72 44 Metastasis 0.43 -0.50 1.29 1052.95 1.00 566 65 37 7 TRUE 0.48
melanoma NRAS_Q61R MED12 72 44 Tumor Type:overall 0.41 -4.18 4.32 1594.45 1.00 566 65 37 7 TRUE 0.08
melanoma NRAS_Q61R NF1 69 230 Metastasis -1.56 -2.47 -0.80 1377.41 1.00 447 63 224 6 TRUE 3.61
melanoma NRAS_Q61R NF1 10 67 Primary -0.47 -1.97 1.00 1409.10 1.00 189 7 64 3 TRUE 0.26
melanoma NRAS_Q61R NF1 79 297 Tumor Type:overall -1.02 -2.75 0.91 1458.18 1.00 636 70 288 9 TRUE 0.57
melanoma NRAS_Q61R FLT1 71 96 Metastasis 0.03 -0.68 0.70 1461.60 1.00 526 61 86 10 FALSE 0.03
melanoma NRAS_Q61R FLT1 10 26 Primary 0.31 -1.07 1.64 1636.82 1.00 216 8 24 2 FALSE 0.18
melanoma NRAS_Q61R FLT1 81 122 Tumor Type:overall 0.16 -1.33 1.94 1288.07 1.00 742 69 110 12 FALSE 0.08
melanoma NRAS_Q61R RPTOR 69 37 Metastasis -1.07 -2.80 0.30 1531.32 1.00 563 67 35 2 FALSE 0.73
melanoma NRAS_Q61R RPTOR 9 14 Primary -1.63 -5.31 0.62 1336.27 1.00 218 9 14 0 FALSE 0.54
melanoma NRAS_Q61R RPTOR 78 51 Tumor Type:overall -1.30 -3.98 0.96 1537.13 1.00 781 76 49 2 FALSE 0.54
melanoma NRAS_Q61R SF3B1 69 53 Metastasis -0.16 -1.13 0.69 1389.33 1.00 549 64 48 5 TRUE 0.14
melanoma NRAS_Q61R SF3B1 9 39 Primary 0.03 -1.47 1.35 1560.23 1.00 194 7 37 2 TRUE 0.02
melanoma NRAS_Q61R SF3B1 78 92 Tumor Type:overall -0.09 -1.87 1.69 1587.87 1.00 743 71 85 7 TRUE 0.04
melanoma NRAS_Q61R ROS1 71 199 Metastasis -0.50 -1.14 0.06 1475.38 1.00 472 58 186 13 TRUE 0.97
melanoma NRAS_Q61R ROS1 10 55 Primary -0.02 -1.26 1.32 1350.81 1.00 203 7 52 3 TRUE 0.01
melanoma NRAS_Q61R ROS1 81 254 Tumor Type:overall -0.27 -1.84 1.44 1490.18 1.00 675 65 238 16 TRUE 0.14
melanoma NRAS_Q61R FLT3 70 66 Metastasis 0.02 -0.82 0.75 1507.43 1.00 555 63 59 7 TRUE 0.02
melanoma NRAS_Q61R FLT3 9 14 Primary 0.14 -1.66 1.74 1206.67 1.00 224 8 13 1 TRUE 0.06
melanoma NRAS_Q61R FLT3 79 80 Tumor Type:overall 0.05 -1.73 1.78 1384.38 1.00 779 71 72 8 TRUE 0.02
melanoma NRAS_Q61R AXL 69 49 Metastasis -1.58 -3.59 -0.08 1542.59 1.00 556 68 48 1 FALSE 1.11
melanoma NRAS_Q61R AXL 9 14 Primary -0.71 -3.13 1.56 1406.68 1.00 219 8 13 1 FALSE 0.26
melanoma NRAS_Q61R AXL 78 63 Tumor Type:overall -1.11 -3.44 1.18 1518.54 1.00 775 76 61 2 FALSE 0.47
melanoma NRAS_Q61R PIK3CG 69 81 Metastasis -0.85 -2.01 0.08 1332.61 1.00 539 65 77 4 FALSE 0.99
melanoma NRAS_Q61R PIK3CG 9 25 Primary -0.59 -2.41 1.11 1445.26 1.00 215 8 24 1 FALSE 0.29
melanoma NRAS_Q61R PIK3CG 78 106 Tumor Type:overall -0.70 -2.68 1.22 1494.92 1.00 754 73 101 5 FALSE 0.35
melanoma NRAS_Q61R EGFR 70 54 Metastasis -0.69 -2.00 0.37 1377.30 1.00 566 67 51 3 TRUE 0.60
melanoma NRAS_Q61R EGFR 9 13 Primary -0.21 -2.22 1.74 1347.90 1.00 223 8 12 1 TRUE 0.08
melanoma NRAS_Q61R EGFR 79 67 Tumor Type:overall -0.45 -2.52 1.52 1547.40 1.00 789 75 63 4 TRUE 0.19
melanoma NRAS_Q61R ARID1B 69 55 Metastasis 0.03 -0.89 0.84 1264.44 1.00 555 63 49 6 TRUE 0.03
melanoma NRAS_Q61R ARID1B 9 20 Primary 0.03 -1.78 1.50 1609.65 1.00 222 8 19 1 TRUE 0.01
melanoma NRAS_Q61R ARID1B 78 75 Tumor Type:overall 0.04 -1.63 1.64 1607.77 1.00 777 71 68 7 TRUE 0.02
melanoma NRAS_Q61R GNA11 70 34 Metastasis -1.93 -4.64 -0.15 1299.09 1.00 577 69 33 1 TRUE 1.06
melanoma NRAS_Q61R GNA11 9 20 Primary -2.27 -6.16 0.19 1321.50 1.00 215 9 20 0 TRUE 0.80
melanoma NRAS_Q61R GNA11 79 54 Tumor Type:overall -2.04 -5.35 0.40 1375.34 1.00 792 78 53 1 TRUE 0.80
melanoma NRAS_Q61R INSR 69 54 Metastasis 0.12 -0.80 0.90 1306.59 1.00 563 63 48 6 FALSE 0.10
melanoma NRAS_Q61R INSR 9 13 Primary 0.26 -1.47 1.77 1472.88 1.00 219 8 12 1 FALSE 0.13
melanoma NRAS_Q61R INSR 78 67 Tumor Type:overall 0.20 -1.56 1.97 1433.15 1.00 782 71 60 7 FALSE 0.09
melanoma NRAS_Q61R ERG 69 39 Metastasis -2.14 -4.92 -0.25 864.90 1.00 564 68 38 1 FALSE 1.11
melanoma NRAS_Q61R ERG 9 14 Primary -2.41 -6.16 0.30 1330.55 1.00 220 9 14 0 FALSE 0.77
melanoma NRAS_Q61R ERG 78 53 Tumor Type:overall -2.20 -5.41 0.33 1031.13 1.00 784 77 52 1 FALSE 0.88
melanoma NRAS_Q61R MET 70 63 Metastasis -0.76 -1.96 0.19 1400.46 1.00 555 67 60 3 TRUE 0.75
melanoma NRAS_Q61R MET 9 22 Primary 0.21 -1.49 1.88 1168.95 1.00 218 7 20 2 TRUE 0.09
melanoma NRAS_Q61R MET 79 85 Tumor Type:overall -0.29 -2.28 1.67 1211.29 1.00 773 74 80 5 TRUE 0.11
melanoma NRAS_Q61R BRAF 70 245 Metastasis -2.83 -4.21 -1.78 1410.73 1.00 386 67 242 3 TRUE 5.36
melanoma NRAS_Q61R BRAF 9 54 Primary -3.35 -7.03 -0.90 1335.55 1.00 183 9 54 0 TRUE 1.45
thyroid cancer NRAS_Q61R BRAF 32 107 Metastasis -4.41 -7.42 -2.40 1000.13 1.01 124 32 107 0 TRUE 3.33
thyroid cancer NRAS_Q61R BRAF 31 66 Primary -4.04 -6.52 -2.09 217.46 1.02 116 30 65 1 TRUE 3.46
melanoma NRAS_Q61R BRAF 79 299 Tumor Type:overall -2.97 -5.63 -0.56 1387.65 1.00 569 76 296 3 TRUE 1.68
thyroid cancer NRAS_Q61R BRAF 63 173 Tumor Type:overall -4.19 -6.75 -2.16 664.06 1.01 240 62 172 1 TRUE 3.49
melanoma NRAS_Q61R TET2 69 67 Metastasis -0.53 -1.61 0.37 1326.10 1.00 542 65 63 4 TRUE 0.52
melanoma NRAS_Q61R TET2 9 25 Primary 0.20 -1.33 1.79 1513.75 1.00 215 7 23 2 TRUE 0.10
melanoma NRAS_Q61R TET2 78 92 Tumor Type:overall -0.16 -1.89 1.55 1442.48 1.00 757 72 86 6 TRUE 0.07
melanoma NRAS_Q61R PDGFRB 69 55 Metastasis -1.43 -3.18 -0.14 1281.91 1.00 558 67 53 2 TRUE 1.16
melanoma NRAS_Q61R PDGFRB 9 11 Primary -1.91 -5.64 0.62 1125.09 1.00 222 9 11 0 TRUE 0.61
melanoma NRAS_Q61R PDGFRB 78 66 Tumor Type:overall -1.58 -4.09 0.81 1228.95 1.00 780 76 64 2 TRUE 0.67
melanoma NRAS_Q61R CARD11 69 91 Metastasis -1.15 -2.47 -0.14 1344.22 1.00 527 65 87 4 FALSE 1.43
melanoma NRAS_Q61R CARD11 9 21 Primary -1.73 -5.28 0.32 1352.20 1.00 215 9 21 0 FALSE 0.67
melanoma NRAS_Q61R CARD11 78 112 Tumor Type:overall -1.40 -3.69 0.39 1346.96 1.00 742 74 108 4 FALSE 0.72
melanoma NRAS_Q61R CBL 69 64 Metastasis -0.63 -1.79 0.32 1445.31 1.00 543 65 60 4 TRUE 0.61
melanoma NRAS_Q61R CBL 9 19 Primary -0.38 -2.23 1.40 1510.19 1.00 215 8 18 1 TRUE 0.17
melanoma NRAS_Q61R CBL 78 83 Tumor Type:overall -0.49 -2.27 1.21 1370.08 1.00 758 73 78 5 TRUE 0.24
melanoma NRAS_Q61R TP63 70 134 Metastasis -0.21 -0.87 0.43 1406.81 1.00 498 59 123 11 FALSE 0.27
melanoma NRAS_Q61R TP63 11 37 Primary 1.15 -0.12 2.44 1406.59 1.00 210 6 32 5 FALSE 1.05
melanoma NRAS_Q61R TP63 81 171 Tumor Type:overall 0.48 -1.32 2.66 1363.79 1.00 708 65 155 16 FALSE 0.20
melanoma NRAS_Q61R GLI1 67 57 Metastasis -0.91 -2.32 0.18 1215.00 1.00 514 64 54 3 FALSE 0.82
melanoma NRAS_Q61R GLI1 67 57 Tumor Type:overall -0.84 -4.96 3.53 1395.18 1.00 514 64 54 3 FALSE 0.17
melanoma NRAS_Q61R ZFHX3 68 83 Metastasis -0.25 -1.07 0.51 1470.36 1.00 499 60 75 8 FALSE 0.27
melanoma NRAS_Q61R ZFHX3 9 62 Primary -0.78 -2.57 0.51 1463.71 1.00 199 8 61 1 FALSE 0.47
melanoma NRAS_Q61R ZFHX3 77 145 Tumor Type:overall -0.49 -2.36 1.28 1362.34 1.00 698 68 136 9 FALSE 0.23
melanoma NRAS_Q61R MGA 67 73 Metastasis -1.34 -2.76 -0.24 1235.54 1.00 502 64 70 3 FALSE 1.40
melanoma NRAS_Q61R MGA 9 23 Primary -1.88 -5.14 0.22 1164.19 1.00 200 9 23 0 FALSE 0.70
melanoma NRAS_Q61R MGA 76 96 Tumor Type:overall -1.54 -3.98 0.48 1388.67 1.00 702 73 93 3 FALSE 0.73
melanoma NRAS_Q61R KMT2B 42 65 Metastasis -0.26 -1.20 0.52 624.06 1.00 261 35 58 7 FALSE 0.25
melanoma NRAS_Q61R KMT2B 7 30 Primary -1.38 -5.37 0.39 467.57 1.01 117 7 30 0 FALSE 0.42
melanoma NRAS_Q61R KMT2B 49 95 Tumor Type:overall -0.76 -3.38 0.95 1014.91 1.01 378 42 88 7 FALSE 0.30
melanoma NRAS_Q61R ANKRD11 67 57 Metastasis -0.80 -2.06 0.25 1382.94 1.00 518 64 54 3 FALSE 0.74
melanoma NRAS_Q61R ANKRD11 9 19 Primary -0.49 -2.22 1.35 1547.12 1.00 204 8 18 1 FALSE 0.23
melanoma NRAS_Q61R ANKRD11 76 76 Tumor Type:overall -0.64 -2.40 1.34 1613.14 1.00 722 72 72 4 FALSE 0.31
melanoma NRAS_Q61R PGR 67 44 Metastasis -2.95 -7.24 -0.56 1327.46 1.00 521 67 44 0 FALSE 0.99
melanoma NRAS_Q61R PGR 9 12 Primary -0.94 -4.21 1.71 1311.41 1.00 207 8 11 1 FALSE 0.28
melanoma NRAS_Q61R PGR 76 56 Tumor Type:overall -1.82 -5.18 0.98 1278.90 1.00 728 75 55 1 FALSE 0.63
melanoma NRAS_Q61R PLCG2 67 47 Metastasis -0.42 -1.62 0.53 1402.22 1.00 521 64 44 3 FALSE 0.35
melanoma NRAS_Q61R PLCG2 9 16 Primary 0.50 -1.27 2.20 1430.61 1.00 206 7 14 2 FALSE 0.24
melanoma NRAS_Q61R PLCG2 76 63 Tumor Type:overall 0.03 -1.86 2.10 1603.60 1.00 727 71 58 5 FALSE 0.01
melanoma NRAS_Q61R PREX2 41 124 Metastasis -0.54 -1.38 0.21 478.27 1.00 235 33 116 8 FALSE 0.73
melanoma NRAS_Q61R PREX2 8 52 Primary 0.60 -0.73 2.09 1166.09 1.00 110 3 47 5 FALSE 0.37
melanoma NRAS_Q61R PREX2 49 176 Tumor Type:overall 0.06 -1.74 1.99 1433.45 1.00 345 36 163 13 FALSE 0.02
melanoma NRAS_Q61R EPHA7 67 125 Metastasis -1.40 -2.54 -0.49 1517.38 1.00 469 63 121 4 FALSE 2.15
melanoma NRAS_Q61R EPHA7 9 34 Primary -1.10 -2.84 0.63 1188.57 1.00 195 8 33 1 FALSE 0.65
melanoma NRAS_Q61R EPHA7 76 159 Tumor Type:overall -1.25 -3.14 0.63 1274.89 1.00 664 71 154 5 FALSE 0.72
pancreatic cancer KRAS_G12R TP53 71 379 Metastasis 0.69 0.30 1.14 117.00 1.02 207 19 327 52 TRUE 2.81
pancreatic cancer KRAS_G12R TP53 100 567 Primary 0.71 0.33 1.18 103.81 1.03 337 24 491 76 TRUE 3.15
pancreatic cancer KRAS_G12R TP53 171 946 Tumor Type:overall 0.71 0.23 1.18 261.76 1.01 544 43 818 128 TRUE 1.60
pancreatic cancer KRAS_G12R RNF43 67 28 Metastasis -0.07 -0.96 0.72 610.46 1.00 489 64 25 3 TRUE 0.06
pancreatic cancer KRAS_G12R RNF43 96 52 Primary -0.04 -0.86 0.68 571.25 1.00 755 90 46 6 TRUE 0.04
pancreatic cancer KRAS_G12R RNF43 163 80 Tumor Type:overall -0.06 -1.04 0.76 634.30 1.00 1244 154 71 9 TRUE 0.05
pancreatic cancer KRAS_G12R ARID1A 67 58 Metastasis -1.31 -2.44 -0.38 930.76 1.00 460 65 56 2 TRUE 1.82
pancreatic cancer KRAS_G12R ARID1A 96 69 Primary -1.26 -2.41 -0.29 801.51 1.00 737 93 66 3 TRUE 1.78
pancreatic cancer KRAS_G12R ARID1A 163 127 Tumor Type:overall -1.28 -2.49 -0.22 936.01 1.00 1197 158 122 5 TRUE 1.53
pancreatic cancer KRAS_G12R KDM6A 67 24 Metastasis -0.23 -1.38 0.64 1044.01 1.00 491 65 22 2 FALSE 0.18
pancreatic cancer KRAS_G12R KDM6A 96 35 Primary -0.16 -1.19 0.73 945.83 1.00 767 92 31 4 FALSE 0.13
pancreatic cancer KRAS_G12R KDM6A 163 59 Tumor Type:overall -0.20 -1.41 0.80 1035.37 1.00 1258 157 53 6 FALSE 0.14
pancreatic cancer KRAS_G12R CDKN2A 72 121 Metastasis 0.26 -0.43 0.76 1096.71 1.00 430 58 107 14 TRUE 0.42
pancreatic cancer KRAS_G12R CDKN2A 102 173 Primary 0.62 0.16 1.08 376.53 1.01 693 70 141 32 TRUE 1.92
pancreatic cancer KRAS_G12R CDKN2A 174 294 Tumor Type:overall 0.45 -0.39 1.22 1420.87 1.00 1123 128 248 46 TRUE 0.53
pancreatic cancer KRAS_G12R SMAD4 71 108 Metastasis 0.73 0.29 1.12 1044.19 1.00 445 51 88 20 TRUE 3.28
pancreatic cancer KRAS_G12R SMAD4 102 167 Primary 0.76 0.37 1.14 876.14 1.00 692 71 136 31 TRUE 4.03
pancreatic cancer KRAS_G12R SMAD4 173 275 Tumor Type:overall 0.74 0.28 1.19 1119.63 1.00 1137 122 224 51 TRUE 2.62
pancreatic cancer KRAS_G12R KMT2D 68 34 Metastasis -0.24 -1.34 0.84 135.01 1.04 485 63 29 5 FALSE 0.17
pancreatic cancer KRAS_G12R KMT2D 96 32 Primary -1.56 -5.42 0.08 541.12 1.01 771 96 32 0 FALSE 0.53
pancreatic cancer KRAS_G12R KMT2D 164 66 Tumor Type:overall -0.85 -3.43 0.79 1312.09 1.00 1256 159 61 5 FALSE 0.39
pancreatic cancer KRAS_G12R GNAS 71 15 Metastasis -1.37 -6.29 0.40 1246.83 1.00 518 71 15 0 TRUE 0.40
pancreatic cancer KRAS_G12R GNAS 100 47 Primary -0.07 -1.07 0.85 1012.07 1.00 784 94 41 6 TRUE 0.05
pancreatic cancer KRAS_G12R GNAS 171 62 Tumor Type:overall -0.68 -3.51 1.00 1266.27 1.00 1302 165 56 6 TRUE 0.25
pancreatic cancer KRAS_G12R DAXX 67 26 Metastasis -5.51 -12.37 -1.51 718.76 1.00 488 67 26 0 TRUE 1.37
pancreatic cancer KRAS_G12R DAXX 96 27 Primary -5.52 -12.35 -1.50 786.74 1.00 773 96 27 0 TRUE 1.37
pancreatic cancer KRAS_G12R DAXX 163 53 Tumor Type:overall -5.41 -11.90 -1.31 735.33 1.00 1261 163 53 0 TRUE 1.35
pancreatic cancer KRAS_G12R MEN1 67 33 Metastasis -6.09 -12.31 -2.04 174.27 1.02 480 67 33 0 TRUE 1.56
pancreatic cancer KRAS_G12R MEN1 96 44 Primary -6.08 -12.24 -1.97 167.69 1.02 754 96 44 0 TRUE 1.58
pancreatic cancer KRAS_G12R MEN1 163 77 Tumor Type:overall -6.03 -12.31 -1.99 168.40 1.02 1234 163 77 0 TRUE 1.56
pancreatic cancer KRAS_Q61H TP53 12 379 Metastasis 0.14 -0.90 1.10 1483.26 1.00 221 5 372 7 TRUE 0.11
pancreatic cancer KRAS_Q61H TP53 48 567 Primary 0.86 0.25 1.55 1496.69 1.00 351 10 529 38 TRUE 1.96
pancreatic cancer KRAS_Q61H TP53 60 946 Tumor Type:overall 0.48 -0.97 1.86 1428.30 1.00 572 15 901 45 TRUE 0.30
pancreatic cancer KRAS_Q61H RNF43 12 28 Metastasis -1.09 -4.02 1.38 1400.77 1.00 542 11 27 1 TRUE 0.37
pancreatic cancer KRAS_Q61H RNF43 46 52 Primary -2.29 -6.12 -0.01 1434.54 1.00 799 46 52 0 TRUE 0.86
pancreatic cancer KRAS_Q61H RNF43 58 80 Tumor Type:overall -1.65 -5.05 1.16 1402.55 1.00 1341 57 79 1 TRUE 0.54
pancreatic cancer KRAS_Q61H ARID1A 12 58 Metastasis -1.14 -6.23 0.85 1304.52 1.00 513 12 58 0 TRUE 0.30
pancreatic cancer KRAS_Q61H ARID1A 47 69 Primary 0.39 -0.57 1.22 1456.74 1.00 789 41 63 6 TRUE 0.39
pancreatic cancer KRAS_Q61H ARID1A 59 127 Tumor Type:overall -0.38 -3.37 1.52 1341.91 1.00 1302 53 121 6 TRUE 0.12
pancreatic cancer KRAS_Q61H KDM6A 12 24 Metastasis -0.94 -4.73 1.15 1386.03 1.00 544 12 24 0 FALSE 0.27
pancreatic cancer KRAS_Q61H KDM6A 46 35 Primary -0.34 -2.27 1.01 1415.74 1.00 815 44 33 2 FALSE 0.17
pancreatic cancer KRAS_Q61H KDM6A 58 59 Tumor Type:overall -0.61 -3.28 1.55 1478.18 1.00 1359 56 57 2 FALSE 0.22
pancreatic cancer KRAS_Q61H CDKN2A 12 121 Metastasis 0.18 -0.87 1.43 687.46 1.00 480 8 117 4 TRUE 0.12
pancreatic cancer KRAS_Q61H CDKN2A 47 173 Primary -0.37 -1.21 0.39 1429.31 1.00 722 41 167 6 TRUE 0.44
pancreatic cancer KRAS_Q61H CDKN2A 59 294 Tumor Type:overall -0.09 -1.46 1.54 1517.20 1.00 1202 49 284 10 TRUE 0.04
pancreatic cancer KRAS_Q61H SMAD4 12 108 Metastasis -1.62 -6.37 0.37 1367.16 1.00 484 12 108 0 TRUE 0.47
pancreatic cancer KRAS_Q61H SMAD4 48 167 Primary 0.45 -0.24 1.10 1128.05 1.00 728 35 154 13 TRUE 0.70
pancreatic cancer KRAS_Q61H SMAD4 60 275 Tumor Type:overall -0.54 -3.73 1.79 1327.81 1.00 1212 47 262 13 TRUE 0.16
pancreatic cancer KRAS_Q61H KMT2D 12 34 Metastasis -1.75 -5.63 0.59 1115.77 1.00 536 12 34 0 FALSE 0.56
pancreatic cancer KRAS_Q61H KMT2D 46 32 Primary -1.30 -3.97 0.58 1166.92 1.00 822 45 31 1 FALSE 0.57
pancreatic cancer KRAS_Q61H KMT2D 58 66 Tumor Type:overall -1.47 -4.73 0.88 1207.87 1.00 1358 57 65 1 FALSE 0.53
pancreatic cancer KRAS_Q61H GNAS 12 15 Metastasis 1.22 -0.95 3.07 1417.26 1.00 579 10 13 2 TRUE 0.64
pancreatic cancer KRAS_Q61H GNAS 47 47 Primary -0.63 -2.67 0.72 1241.98 1.00 832 46 46 1 TRUE 0.32
pancreatic cancer KRAS_Q61H GNAS 59 62 Tumor Type:overall 0.31 -2.21 2.76 1443.86 1.00 1411 56 59 3 TRUE 0.10
pancreatic cancer KRAS_Q61H DAXX 12 26 Metastasis -4.89 -12.51 -0.22 872.75 1.00 543 12 26 0 TRUE 0.89
pancreatic cancer KRAS_Q61H DAXX 46 27 Primary -4.87 -12.47 -0.22 1064.81 1.00 823 46 27 0 TRUE 0.93
pancreatic cancer KRAS_Q61H DAXX 58 53 Tumor Type:overall -4.68 -12.49 -0.06 947.24 1.00 1366 58 53 0 TRUE 0.88
pancreatic cancer KRAS_Q61H MEN1 12 33 Metastasis -5.17 -12.63 -0.59 883.99 1.01 535 12 33 0 TRUE 1.00
pancreatic cancer KRAS_Q61H MEN1 46 44 Primary -5.24 -12.45 -0.72 760.61 1.00 804 46 44 0 TRUE 1.06
pancreatic cancer KRAS_Q61H MEN1 58 77 Tumor Type:overall -5.02 -12.06 -0.30 761.86 1.00 1339 58 77 0 TRUE 1.00
colorectal cancer KRAS_G12S APC 19 1010 Metastasis 0.16 -0.78 0.97 1186.14 1.00 281 5 996 14 TRUE 0.14
colorectal cancer KRAS_G12S APC 48 1528 Primary 0.58 -0.08 1.31 1486.04 1.00 533 7 1487 41 TRUE 0.98
colorectal cancer KRAS_G12S APC 67 2538 Tumor Type:overall 0.35 -0.74 1.35 1462.41 1.00 814 12 2483 55 TRUE 0.29
 

R version 3.6.1 (2019-07-05)
Platform: x86_64-apple-darwin15.6.0 (64-bit)
Running under: macOS High Sierra 10.13.4

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/3.6/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/3.6/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] here_1.0.1      gt_0.6.0        forcats_0.5.1   stringr_1.4.0  
 [5] dplyr_1.0.9     purrr_0.3.4     readr_2.1.2     tidyr_1.2.0    
 [9] tibble_3.1.7    ggplot2_3.3.6   tidyverse_1.3.1 magrittr_2.0.3 
[13] workflowr_1.7.0

loaded via a namespace (and not attached):
 [1] Rcpp_1.0.8.3     lubridate_1.8.0  getPass_0.2-2    ps_1.7.0        
 [5] assertthat_0.2.1 rprojroot_2.0.3  digest_0.6.29    utf8_1.2.2      
 [9] R6_2.5.1         cellranger_1.1.0 backports_1.4.1  reprex_2.0.1    
[13] evaluate_0.15    httr_1.4.3       pillar_1.7.0     rlang_1.0.2     
[17] readxl_1.4.0     rstudioapi_0.13  whisker_0.4      callr_3.7.0     
[21] jquerylib_0.1.4  checkmate_2.1.0  rmarkdown_2.14   bit_4.0.4       
[25] munsell_0.5.0    broom_0.8.0      compiler_3.6.1   httpuv_1.6.5    
[29] modelr_0.1.8     xfun_0.31        pkgconfig_2.0.3  htmltools_0.5.2 
[33] tidyselect_1.1.2 fansi_1.0.3      withr_2.5.0      crayon_1.5.1    
[37] tzdb_0.3.0       dbplyr_2.2.0     later_1.3.0      rappdirs_0.3.3  
[41] grid_3.6.1       jsonlite_1.8.0   gtable_0.3.0     lifecycle_1.0.1 
[45] DBI_1.1.2        git2r_0.30.1     scales_1.2.0     vroom_1.5.7     
[49] cli_3.3.0        stringi_1.7.6    fs_1.5.2         promises_1.2.0.1
[53] xml2_1.3.3       bslib_0.3.1      ellipsis_0.3.2   generics_0.1.2  
[57] vctrs_0.4.1      tools_3.6.1      bit64_4.0.5      glue_1.6.2      
[61] hms_1.1.1        parallel_3.6.1   processx_3.5.3   fastmap_1.1.0   
[65] yaml_2.3.5       colorspace_2.0-3 rvest_1.0.2      knitr_1.39      
[69] haven_2.5.0      sass_0.4.1